CN104491779A - Application of traditional Chinese medicine preparation in preparing medicine for treating qi-blood deficiency type alopecia areata - Google Patents

Application of traditional Chinese medicine preparation in preparing medicine for treating qi-blood deficiency type alopecia areata Download PDF

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CN104491779A
CN104491779A CN201410731291.1A CN201410731291A CN104491779A CN 104491779 A CN104491779 A CN 104491779A CN 201410731291 A CN201410731291 A CN 201410731291A CN 104491779 A CN104491779 A CN 104491779A
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radix
chinese medicine
medicine preparation
alopecia areata
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邓凤桂
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GUANGDONG JUZHICHENG TECHNOLOGY Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296Epimedium
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
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    • A61K36/80Scrophulariaceae (Figwort family)
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Abstract

The invention belongs to the technical field of medicines, and relates to application of a traditional Chinese medicine preparation in preparing a medicine for treating qi-blood deficiency type alopecia areata. The traditional Chinese medicine preparation comprises the following components: ginger, prepared polygonum multiflorum, ginkgo leaves, rehmannia glutinosa, cacumen biotae, salvia miltiorrhiza, astragalus membranaceus, cortex albiziae, caulis spatholobi, schisandra chinensis, herba epimedii and kudzu vine roots. The traditional Chinese medicine preparation provided by the invention has the effects of tonifying the liver and the kidney, nourishing the blood and promoting blood circulation, invigorating splenic yang and tonifying qi as well as regulating qi activity, is definite in treatment effect and safe and reliable when used for treating alopecia areata, and can be used as an effective method for treating alopecia areata.

Description

A kind of Chinese medicine preparation is for the preparation of the purposes in treatment QIXUELIANGXU type alopecia areata medicine
Technical field
The invention belongs to medical art, relate to a kind of Chinese medicine preparation for the preparation of the purposes in treatment QIXUELIANGXU type alopecia areata medicine.
Background technology
Modern society, people's operating pressure is large, diet is irregular, often surf the Net, and stay up late, a lot of people's age just starts the puzzlement enduring alopecia to the fullest extent gently.Although depilation phenomenon is given, people's bring what painful constitutionally, and its generation often increases spiritual invisible pressure to people, has a strong impact on work and life.
Alopecia areata is the patchy alopecia trichopathy of a kind of locality suddenly occurred.From name of disease, alopecia areata is similar to the alopecia areata that Chinese medicine is said, mainly relevant with QI and blood deficiency, deficiency of the liver and kindey, qi depression to blood stasis, stagnation of QI due to depression of the liver, blood-deficiency and wind-dry, blood hot air wind producing from etiology and pathogenesis; The multiplex hormone medicine of current western medical treatment, toxic and side effects is large, has certain damage to human body.
The treatment of the traditional Chinese medical science to primary disease have accumulated rich experience, in external treatment, treatment is wiped outward to external Chinese medicine decoction fumigation and wash method with tincture, ointment, ointment, and Oleum Cocois, Rhizoma Zingiberis Recens, the treatment of Chinese medicine patch etc., but consider from curative effect and application comfort level, many application tinctures and Rhizoma Zingiberis Recens wipe treatment outward clinically.In internal treatment, apply traditional ancient prescription plus-minus and use from plan side's plus-minus, also having and use Chinese patent medicine and single medicinal material to treat, but being on the basis of ancient prescription, carry out plus-minus treatment according to etiology and pathogenesis mostly.Such as treat that blood deficiency, blood are tired, blood-heat type all carries out plus-minus treatment by SIWU TANG, to patients with alopecia areata also conventional TONGQIAOHUOXUE Decoction and the Buyang Huanwu Decoction of the tired resistance of blood, the multiplex Qibao Meiran Dan of deficiency of both the liver and kidney and LIUWEI DIHUANG WAN, ERZHI WAN, the multiplex XIAOYAO POWDER plus-minus treatment of stagnation of QI due to depression of the liver, blood-deficiency and wind-dry type should support very red plus-minus with god, the multiplex RENSHEN YANGRONG TANG of QI and blood deficiency person and decoction of ten powerful tonics plus-minus.
Clinically, because the alopecia areata state of an illness is complicated, so multiplex multiple therapy methods, carry out, to reach the effect of Synergistic treatment simultaneously.And Chinese traditional treatment alopecia areata toxic and side effects is little, increasing patient selects traditional Chinese medical herbal treatment primary disease, therefore, strengthens the exploration of primary disease in Chinese medicine, dialectically treats, and is more of value to healing alopecia areata.
Summary of the invention
The invention provides a kind of Chinese medicine preparation for the preparation of the purposes in treatment QIXUELIANGXU type alopecia areata medicine, this Chinese medicine preparation medical material is easy to get, with low cost, determined curative effect, toxic and side effects is little, and it is obtained by following raw material: Rhizoma Zingiberis Recens, Radix Polygoni Multiflori Preparata, Folium Ginkgo, Radix Rehmanniae Preparata, Cacumen Platycladi, Radix Salviae Miltiorrhizae, the Radix Astragali, Cortex Albiziae, Caulis Spatholobi, Fructus Schisandrae Chinensis, Herba Epimedii, Radix Puerariae.
Chinese medicine preparation of the present invention, described Rhizoma Zingiberis Recens, pungent, tepor.Return lung, spleen, stomach warp.Induce sweat cold expelling, warming middle-JIAO to arrest vomiting, preventing phlegm from forming and stopping coughing.For anemofrigid cold, gastrofrigid vomiting, cold-phlegm is coughed.
Radix Polygoni Multiflori Preparata, bitter, sweet, puckery, temperature.Return liver, the heart, kidney channel.Invigorating the liver and kidney, benefiting essence-blood, black beard and hair, bone and muscle strengthening.For blood deficiency and yellow complexion, vertigo and tinnitus, early whitening of beard and hair, soreness of the waist and knees, numb limbs and tense tendons, bleeding not during menses, chronic malaria body is empty; Hyperlipidemia.
Folium Ginkgo is sweet, bitter, puckery, flat.GUIXIN, lung meridian.Astringe the lung, relieving asthma, blood circulation promoting and blood stasis dispelling, pain relieving.For cough and asthma due to lung deficiency; Coronary heart disease, angina pectoris, hyperlipidemia.
Radix Rehmanniae Preparata, sweet, temperature.Return liver, kidney channel.Enrich blood moist, beneficial essence fills out marrow.For soreness of the waist and knees, hepatic and renal YIN deficiency, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, and blurred vision is failed to understand, early whitening of beard and hair.
Cacumen Platycladi, bitter, puckery, cold.Return lung, liver, spleen channel.Cooling blood for hemostasis, growing and blacking hair.For hematemesis and epistaxis, spitting of blood, has blood in stool, metrostaxis, heat in blood alopecia, early whitening of beard and hair.
Radix Salviae Miltiorrhizae, bitter, be slightly cold.GUIXIN, Liver Channel.Stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness.For menoxenia, amenorrhea dysmenorrhea , lumps in the chest and abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.
The Radix Astragali, sweet, temperature.Return lung, spleen channel.Invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst;
Cortex Albiziae, sweet, flat.GUIXIN, liver, lung meridian.Resolving stagnation for tranquilization, promoting blood circulation and detumescence.For irritability, melancholy insomnia, lung abscess skin ulcer swells, and falls and flutters the pain of injury.
Caulis Spatholobi, sweet, bitter, temperature.Return liver, kidney channel.Enrich blood and invigorate blood circulation, dredging collateral, relaxing muscles and tendons to promote blood circulation.For blood deficiency and yellow complexion, menoxenia, amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.
Fructus Schisandrae Chinensis, sweet, acid, temperature.Return kidney, lung meridian.Nourishing kidney, astringes the lung, and promotes the production of body fluid, bone and muscle strengthening, arresting seminal emission.For impotence and seminal emission, few abdomen cold type of pain, chronic diarrhea chronic dysentery, muscles and bones flaccidity is soft, and the deficiency of the lung is breathed with cough.
Herba Epimedii, acrid, sweet, warm.Return liver, kidney channel.Kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.For impotence and seminal emission, muscles and bones flaccidity is soft, rheumatic arthralgia, numbness contracture; Climacteric hypertension.
Radix Puerariae, sweet, pungent, cool.Return spleen, stomach warp.Expelling pathogenic factors from muscles for reducing heat, promotes the production of body fluid, rash, yang invigorating antidiarrheal.For fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, has loose bowels; Hypertension neck pain.
In Chinese medicine preparation of the present invention, wherein the Radix Astragali has effect of tonifying Qi and lifting yang; Cortex Albiziae and Caulis Spatholobi have the effect of enriching blood, nourishing blood; Cacumen Platycladi removing heat from blood is moisturized, growing and blacking hair; Radix Polygoni Multiflori Preparata, Fructus Schisandrae Chinensis, Herba Epimedii and Radix Rehmanniae Preparata can the liver and the kidney tonifying, and make smart sufficient blood prosperous, hair growth promoting is active; Radix Salviae Miltiorrhizae and Folium Ginkgo have blood circulation promoting and blood stasis dispelling; Radix Puerariae and Rhizoma Zingiberis Recens can increase the blood circulation of local, harmonizing the functional activities of vital QI.The present invention is pure Chinese medicinal preparation, follows strengthening vital QI to eliminate pathogenic factors, the Therapeutic Principle for the treatment of both the principal and secondary aspects of a disease, and all medicines share, and plays effect of the liver and the kidney tonifying, nourshing blood and promoting blood circulation, ascending YANG and invigorating QI and harmonizing the functional activities of vital QI altogether.
The technical scheme adopted for solving its technical problem is that described Chinese medicine preparation is made up of the medicine material of following weight: Rhizoma Zingiberis Recens 2-10 part, Radix Polygoni Multiflori Preparata 5-13 part, Folium Ginkgo 8-13 part, Radix Rehmanniae Preparata 5-13 part, Cacumen Platycladi 5-13 part, Radix Salviae Miltiorrhizae 8-14 part, Radix Astragali 8-31 part, Cortex Albiziae 5-13 part, Caulis Spatholobi 5-13 part, Fructus Schisandrae Chinensis 5-13 part, Herba Epimedii 2-10 part, Radix Puerariae 2-10 part for the preparation of the purposes in treatment QIXUELIANGXU type alopecia areata medicine.
The preferred technical solution of the present invention is, described Chinese medicine preparation is obtained by the raw material of following weight portion: 6 parts, Rhizoma Zingiberis Recens, Radix Polygoni Multiflori Preparata 9 parts, Folium Ginkgo 11 parts, 9 parts, Radix Rehmanniae Preparata, Cacumen Platycladi 9 parts, Radix Salviae Miltiorrhizae 12 parts, the Radix Astragali 20 parts, Cortex Albiziae 9 parts, Caulis Spatholobi 9 parts, Fructus Schisandrae Chinensis 9 parts, Herba Epimedii 6 parts, Radix Puerariae 6 parts.
Present invention also offers the preparation method of the Chinese medicine preparation of described purposes, specific as follows: the dry medicine raw material getting ingredients in prescription, removing impurity, cleaning, drying, decoct twice, filtering medicinal residues extracting juice, for subsequent use after mixing twice filtrate cooling.This basis adds adjuvant conventional formulation technique and can obtain various dosage forms conventional clinically.Those skilled in the art directly can be used as medicine on obtained active constituents of medicine basis of the present invention to take or add on pharmaceutics acceptable adjuvant routinely technique be prepared into required preparation.As the oral drugs of the solid dosage form such as conventional tablet (dispersible tablet, effervescent tablet, oral cavity disintegration tablet, buccal tablet, chewable tablet, effervescent tablet), capsule (hard capsule, soft capsule), granule, pill (drop pill), powder can be made, the oral drugs of the liquid forms such as syrup, oral liquid, water preparation, mixture, decoction also can be made.Therefore, in this Chinese medicine preparation except effective ingredient, pharmaceutically acceptable adjuvant can also be contained.In prepared decoction, every milliliter of medicinal liquid containing crude drug amount 0.1g, 1 dose/day, when being used for the treatment of alopecia areata, sooner or later ante cibum each decoction being taken warmly 1 time, each 150mL.
The present invention also asks to protect the purposes of above-mentioned Chinese medicine preparation in preparation treatment QIXUELIANGXU type alopecia areata medicine.After by the safety evaluatio of Chinese medicine preparation of the present invention, clinical case is selected to observe in 120 known treated routine QIXUELIANGXU type patients with alopecia areatas, the treatment total effective rate for the treatment of group is 98.33%, matched group is 75.00%, visible, the treatment total effective rate for the treatment of group is apparently higher than matched group, and P<0.05, has statistical significance.Result shows, Chinese medicine preparation of the present invention has extremely significant curative effect to treatment QIXUELIANGXU type patients with alopecia areata.Treatment group follows up a case by regular visits to 1 year, and no case was recurrence, treatments period has no adverse reaction.Chinese medicine preparation each side of the present invention medicine conbined usage has the effects such as the liver and the kidney tonifying, nourshing blood and promoting blood circulation, ascending YANG and invigorating QI and harmonizing the functional activities of vital QI, remarkable improvement result is played to the blood circulation of local, the growth of remarkable promotion hair, serves the remarkable result that treatment alopecia areata particularly treats QIXUELIANGXU type alopecia areata after Chinese medicine preparation prescription of the present invention.
The preparation technology of Chinese medicine preparation of the present invention medicine simple to operation, former is easy to get, with low cost, follow the prescriptions principle of the traditional Chinese medical science, untoward reaction and side effect significantly reduce, safety coefficient is high, through clinical practice checking, its determined curative effect, mild in medicine property and, there is not toxic and side effects and serious adverse reaction, alopecia areata particularly QIXUELIANGXU type alopecia areata can be treated preferably.
Detailed description of the invention
Further describe the present invention below by way of specific embodiment, but the present invention is not limited only to following specific embodiment.Within the scope of the invention or not departing from content of the present invention, spirit and scope, the change carried out the present invention, combination or replacement, be apparent for a person skilled in the art, and be included within the scope of the present invention.
embodiment 1,prescription 1
The each raw material of the present invention is taken: 3 parts, Rhizoma Zingiberis Recens, Radix Polygoni Multiflori Preparata 6 parts, Folium Ginkgo 9 parts, 6 parts, Radix Rehmanniae Preparata, Cacumen Platycladi 6 parts, Radix Salviae Miltiorrhizae 9 parts, the Radix Astragali 9 parts, Cortex Albiziae 6 parts, Caulis Spatholobi 6 parts, Fructus Schisandrae Chinensis 6 parts, Herba Epimedii 3 parts, Radix Puerariae 3 parts by following weight portion.
embodiment 2,prescription 2
The each raw material of the present invention is taken: 9 parts, Rhizoma Zingiberis Recens, Radix Polygoni Multiflori Preparata 12 parts, Folium Ginkgo 12 parts, 12 parts, Radix Rehmanniae Preparata, Cacumen Platycladi 12 parts, Radix Salviae Miltiorrhizae 15 parts, the Radix Astragali 30 parts, Cortex Albiziae 12 parts, Caulis Spatholobi 12 parts, Fructus Schisandrae Chinensis 12 parts, Herba Epimedii 9 parts, Radix Puerariae 9 parts by following weight portion.
embodiment 3,prescription 3
The each raw material of the present invention is taken: 3 parts, Rhizoma Zingiberis Recens, Radix Polygoni Multiflori Preparata 6 parts, Folium Ginkgo 12 parts, 6 parts, Radix Rehmanniae Preparata, Cacumen Platycladi 12 parts, Radix Salviae Miltiorrhizae 9 parts, the Radix Astragali 30 parts, Cortex Albiziae 6 parts, Caulis Spatholobi 12 parts, Fructus Schisandrae Chinensis 6 parts, Herba Epimedii 9 parts, Radix Puerariae 3 parts by following weight portion.
embodiment 4,prescription 4
The each raw material of the present invention is taken: 9 parts, Rhizoma Zingiberis Recens, Radix Polygoni Multiflori Preparata 12 parts, Folium Ginkgo 9 parts, 12 parts, Radix Rehmanniae Preparata, Cacumen Platycladi 6 parts, Radix Salviae Miltiorrhizae 15 parts, the Radix Astragali 9 parts, Cortex Albiziae 12 parts, Caulis Spatholobi 6 parts, Fructus Schisandrae Chinensis 12 parts, Herba Epimedii 3 parts, Radix Puerariae 9 parts by following weight portion.
embodiment 5,prescription 5
The each raw material of the present invention is taken: 6 parts, Rhizoma Zingiberis Recens, Radix Polygoni Multiflori Preparata 9 parts, Folium Ginkgo 11 parts, 9 parts, Radix Rehmanniae Preparata, Cacumen Platycladi 9 parts, Radix Salviae Miltiorrhizae 12 parts, the Radix Astragali 20 parts, Cortex Albiziae 9 parts, Caulis Spatholobi 9 parts, Fructus Schisandrae Chinensis 9 parts, Herba Epimedii 6 parts, Radix Puerariae 6 parts by following weight portion.
Preparation technology: the dry medicine raw material getting ingredients in prescription, removing impurity, cleaning, drying, decoct twice, filtering medicinal residues extracting juice, mixes twice filtrate, namely obtains decoction after cooling, and every milliliter of medicinal liquid is containing crude drug amount 0.1g, 1 dose/day, when being used for the treatment of alopecia areata, each decoction being taken warmly 1 time sooner or later, each 150mL.Those skilled in the art can also add or not add adjuvant conventional formulation technique on this basis can obtain the conventional oral formulations such as decoction, tablet, capsule, granule or powder.
embodiment 6the present invention is for the preparation of the clinical data of the purposes in treatment QIXUELIANGXU type alopecia areata medicine
One, case-data: patient, as object of study, with table of random number, is divided into treatment group and matched group by the 120 routine QIXUELIANGXU type patients with alopecia areatas meeting Screening Diagnosis standard at random that choose hospital's Dermatology and outpatient service.Treatment group 60 example, man 40 example, female 20 example, age 23-58 year, the mean age (34.3 ± 5.44) year, the course of disease 2 months-9 months, average course of disease (4.7 ± 0.27) moon.Matched group 60 example, man 44 example, female 16 example, year 21-59 year, the mean age (33.1 ± 5.34) year, the course of disease 1 month-9 months, average course of disease (4.5 ± 0.28) moon.Patient all shows as the alopecia district that scalp catches sight of circle or ellipse, diameter l-8cm, and the many persons of number can be fused into irregular patch, skin smooth NIP, mostly without obvious subjective symptoms.Two groups of patient's physical data no significant differences.
Two, case selection:
1, diagnostic criteria:
1) according to the Western medicine diagnose standard formulation about alopecia areata in " new Chinese medicine guideline of clinical investigations the 3rd volume ":
(1) suddenly or hair flaking in a short time, single-shot or multiple, the even whole alopecia of hair (alopecia totalis), eyebrow, armpit hair, pubes, beard and fine hair on birds or animals hair come off (alopecia universalis);
(2) alopecia district color of the leather is normal, without obvious inflammatory reaction.
2) formulate with reference to the deficiency of both QI and blood in alopecia areata in " Surgery of Chinese Medicine ":
How after being ill or puerperal hair be that speckle shape comes off, and increase the weight of in gradual, scope mountain is little and large, and hypotrichosis is withered, and touch easily takes off; Companion's lip is white, cardiopalmus, lazy speech of breathing hard, fatigue and weakness; Light red tongue, thready and weak pulse.
2, inclusive criteria:
(1) the diagnostic criteria person of the traditional Chinese medical science and doctor trained in Western medicine is met;
(2) age is between 18-65 year;
Without any therapist within (3) 2 weeks.
3. exclusion standard
(1) the severe primary disease Huo Jing Zhong patients such as cardiovascular, cerebrovascular, liver, kidney and hemopoietic system are associated with.
(2) gestation or women breast-feeding their children.
(3) known allergic constitution or those who are allergic to this drug.
(4) congenital alopecia: acomia or see the bad and rare person of hair development wholly or in part for genetic reasons.
(5) posteriority alopecia: endocrine dysfunction disease, serious acute infectious disease, chronic disease is as tuberculosis, and dermatosis is as syphilis, leprosy etc. and because of causers such as medicines.
(6) Cicatricial baldness: infective factors is as tinea favosa, healthy hair folliculitis etc., some non-infectious dermatosis is as liquor-saturated in flat tongue, local scleroderma, DLE etc., vegetation is as sebaceous nevus, basal cell carcinoma etc., and other are as machinery, wound, radioactivity reason causer.
(7) do not meet inclusive criteria, not by regulation medication, cannot curative effect be judged, or data is not congruent affects the treatment or safety judgement person.
Three, usage and dosage:
Treatment group: crude drug prepared by Example 5, decoct twice, filtering medicinal residues extracting juice, mixes twice filtrate, and after cooling, extracting juice 300ml(every milliliter of medicinal liquid is containing crude drug amount 0.1g) be 1 dose, 1 dose/day, early, each decoction being taken warmly 1 time before supper, each 150ml.Within 30 days, be a course for the treatment of, treat 2 courses for the treatment of continuously.
The oral Tianma shouwu capsules of matched group (the accurate word Z20050819 of traditional Chinese medicines) 6 tablets/time, 3 times/day, the course for the treatment of is 60 days.
Treatments period, irritating shampoo is forbidden in two groups of affected parts, forbids overheated or excessively cool washing head.Rule of life simultaneously, fasting or few edible oil explode, pungent irritating food.
Four, efficacy assessment standard:
With reference to " Chinese medical disease Standardization of diagnosis and curative effect ".
Cure: patient's alopecia position stops alopecia, and all grow hair, do not have relapse indications and newborn alopecia situation, hair quality is denser.
Effective: what patient's alopecia position grew newly sends out >=70%, and skin lesion symptom appears slightly coming off in newborn hair.
Effective: patient's alopecia position grows new of 30% ~ 69%, and skin lesion symptom appears significantly coming off in newborn hair.
Invalid: the new < 30% that patient's alopecia position grows, there is repeatedly coming off skin lesion symptom in newborn hair.
Five, therapeutic effect:
Without coming off case in therapeutic process, all complete clinical observation.The treatment total effective rate for the treatment of group is 98.33%, and matched group is 75.00%, visible, and the treatment total effective rate for the treatment of group is apparently higher than matched group, and P<0.05, has statistical significance, and in therapeutic process, two groups all do not occur serious untoward reaction.Concrete outcome, in table 1, shows that using Chinese medicine preparation of the present invention to treat alopecia areata particularly treats the alopecia areata determined curative effect belonging to QI and blood deficiency disease, safe and reliable, can be used as the effective ways for the treatment of QI and blood deficiency alopecia areata, is worth of widely use in clinical.
The comparitive study of table 1. treatment group and matched group
Group Recovery from illness Effective Effectively Invalid Total effective (rate)
Treatment group 20 34 5 1 59(98.33%)
Matched group 7 26 12 15 45(75.00%)

Claims (5)

1. a Chinese medicine preparation is for the preparation of the purposes in treatment QIXUELIANGXU type alopecia areata medicine, it is characterized in that, described Chinese medicine preparation is obtained by following raw material: Rhizoma Zingiberis Recens, Radix Polygoni Multiflori Preparata, Folium Ginkgo, Radix Rehmanniae Preparata, Cacumen Platycladi, Radix Salviae Miltiorrhizae, the Radix Astragali, Cortex Albiziae, Caulis Spatholobi, Fructus Schisandrae Chinensis, Herba Epimedii, Radix Puerariae.
2. purposes as claimed in claim 1, it is characterized in that, described Chinese medicine preparation is obtained by the raw material of following weight portion: Rhizoma Zingiberis Recens 2-10 part, Radix Polygoni Multiflori Preparata 5-13 part, Folium Ginkgo 8-13 part, Radix Rehmanniae Preparata 5-13 part, Cacumen Platycladi 5-13 part, Radix Salviae Miltiorrhizae 8-14 part, Radix Astragali 8-31 part, Cortex Albiziae 5-13 part, Caulis Spatholobi 5-13 part, Fructus Schisandrae Chinensis 5-13 part, Herba Epimedii 2-10 part, Radix Puerariae 2-10 part.
3. purposes as claimed in claim 2, it is characterized in that, described Chinese medicine preparation is obtained by the raw material of following weight portion: 6 parts, Rhizoma Zingiberis Recens, Radix Polygoni Multiflori Preparata 9 parts, Folium Ginkgo 11 parts, 9 parts, Radix Rehmanniae Preparata, Cacumen Platycladi 9 parts, Radix Salviae Miltiorrhizae 12 parts, the Radix Astragali 20 parts, Cortex Albiziae 9 parts, Caulis Spatholobi 9 parts, Fructus Schisandrae Chinensis 9 parts, Herba Epimedii 6 parts, Radix Puerariae 6 parts.
4. the purposes as described in as arbitrary in claim 1-3, it is characterized in that, described Chinese medicine preparation is oral formulations.
5. purposes as claimed in claim 4, it is characterized in that, described oral formulations is capsule, tablet, powder, decoction.
CN201410731291.1A 2014-12-05 2014-12-05 Application of traditional Chinese medicine preparation in preparing medicine for treating qi-blood deficiency type alopecia areata Pending CN104491779A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1089850A (en) * 1993-01-14 1994-07-27 冯纯礼 Alopecia pill
WO1996010387A2 (en) * 1994-09-30 1996-04-11 The Boots Company Plc Hair stimulant composition

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1089850A (en) * 1993-01-14 1994-07-27 冯纯礼 Alopecia pill
WO1996010387A2 (en) * 1994-09-30 1996-04-11 The Boots Company Plc Hair stimulant composition

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Title
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***等: "《皮肤性病科顽症金方》", 31 January 2007, 科学技术文献出版社 *
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Application publication date: 20150408