CN104491626A - Chinese patent medicine preparation used for treating pediatric adenoidal hypertrophy - Google Patents

Chinese patent medicine preparation used for treating pediatric adenoidal hypertrophy Download PDF

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CN104491626A
CN104491626A CN201510026300.1A CN201510026300A CN104491626A CN 104491626 A CN104491626 A CN 104491626A CN 201510026300 A CN201510026300 A CN 201510026300A CN 104491626 A CN104491626 A CN 104491626A
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王静
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    • A—HUMAN NECESSITIES
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Abstract

The invention belongs to the technical field of traditional Chinese medicine preparations, and relates to a Chinese patent medicine preparation used for treating pediatric adenoidal hypertrophy. The Chinese patent medicine preparation comprises, by weight, 15 parts to 30 parts of honeysuckle, 10 parts to 20 parts of fructus forsythiae, 10 parts to 20 parts of fritillaria thunbergii miq, 10 parts to 15 parts of radix paeoniae rubra, 10 parts to 20 parts of poria cocos, 30 parts to 40 parts of pearl barley, 9 parts to 15 parts of spina gleditsiae, 6 parts to 12 parts of trigone, 6 parts to 12 parts of hedgehog hide, 3 parts to 15 parts of concretio silicea bambusae, 9 parts to 15 parts of turtle shells, 10 parts to 20 parts of rhizoma dioscoreae sheets and 5 parts of 10 parts of folium mori. The components are manufactured into the granular or honey-bolus-shaped or paste preparation through an existing Chinese patent medicine preparation process according to the ratios, and the Chinese patent medicine preparation is used for treating pediatric adenoidal hypertrophy and is good in curative effect, scientific in ratio, convenient to use, beneficial to children patient medicine taking and free of toxic and side effects.

Description

A kind of Chinese patent medicine preparation for the treatment of children's's adenoid vegetation
Technical field:
The invention belongs to Chinese drug preparation technique field, relate to a kind of Chinese patent medicine preparation for the treatment of children's's adenoid vegetation.
Background technology:
Adenoid vegetation is Common Pediatric Diseases, and proventriculus type (adenoids) is also pharyngeal tonsil (pharyngeal tonsils), is the tonsil of a group lymphoid tissue, similar palate, is attached to the rear wall of nasopharynx, and surface is in Fructus Citri tangerinae lobe sample.Child, in the process of normal development, can have tonsil, proventriculus type physiological hypertrophy.Proventriculus type is molecular marker for increased proliferation period when children's 4-6 year, and adolescence is atrophy gradually later.Adenoid vegetation often with snoring, feel suffocated, the symptom such as mouth breathing, and the disease such as intractable rhinitis, sinusitis, secretory otitis media, more seriously may cause maxillofacial development obstacle and, intelligence physical growth hypoevolutism, meanwhile, adenoid vegetation is also one of pediatric obstructive sleep apnea low syndrome (OSAHS) modal cause of disease.Nasal cavity Microendoscopic proventriculus type usually blocks Choanal more than 2/3, even oppresses pharyngeal opening of auditory tube.Nuclear mangetic resonance-CT (MR) nasopharynx part median sagittal plane image is measured proventriculus type maximum gauge with from hard palate upper limb to the ratio of distances constant (A/N than) of the Sphenooccipital cartilage joint portion of basis cranii and air flue gap (pharyngeal airway space afterwards, PAS) width (soft palate surface and proventriculus type surperficial between effective chimney width), A/N is than >=0.71, PAS≤3mm is pathologic hypertrophy standard and surgical indication.Along with increasing gradually of children's's adenoid vegetation case, the harm that this disease causes receives the concern of pediatrician more and more.
At present, for the Adenoidal western medical treatment of children's mainly expectant treatment and operative treatment, expectant treatment is only only limitted to improve BITONG gas, preventing cold, enhancing immunity, wish to increase proventriculus type atrophy and the state of an illness may be alleviated gradually with the age, but often effect of conservative treatment is not good for the infant serious for adenoid vegetation, finally selects operative treatment.About there is in North America the infant of 30% to excise tonsil and proventriculus type, but only have the infant of 1% to meet Operation indication.Proventriculus type has immune defense function, therefore can cause part infant hypoimmunity after excision, excise proventriculus type is a kind of invasive surgery simultaneously, and operative site is close to basis cranii, easily cause the danger of the complication such as wound surface is hemorrhage, the Adenoidal infant of partial surgical resection still has the probability of recurrence.
Adenoid vegetation belongs to " sucutaneous nodule " category in motherland's medical science, and " danxi's experiential therapy " is called: " have tuberculosis in ordinary person's women's head-ornaments, neck cheek, body, bitterly not red, the person that do not do pus, all expectorant note also." how to be formed by phlegm-damp oozing in the body, proventriculus type is positioned at nasopharynx part, lung opening at nose, swallows the door into lung, and children's's lungs are tender and lovely, weakened defensive QI, controls joint and haves no right, and water Tianjin is lost in defeated cloth, and lime set becomes expectorant; The spleen tending to insufficiency usually, transporting mistake department, gather and wet into expectorant, above store in lung, therefore primary disease diseased region is mainly at lung spleen, pathogenesis key is that lung-heat is flourishing, dysfunction of the spleen in transportation, and pyretic toxicity stops up lung, fluid transformed into phlegm by fire; Dysfunction of the spleen in transportation, stops in turbid damp, condenses into expectorant, and heat-phlegm stagnates, and venation numbness hinders, therefore the expectorant stasis of blood main pathological product that is it, pyretic toxicity runs through whole pathological process, is the Fundamentals that disease occurs, develops and lapse to, legislation removing heat-phlegm, detoxification and removing stasis.Although current Children Treated with Chinese Traditional Drugs adenoid vegetation search time is shorter, but its few side effects, the effect not easily advantage such as repeatedly lastingly, more and more paid attention to, but inquiry document finds, there is no specification patent medicine so far, and all based on Chinese medicine decoction, infant is difficult to accept, medication is inconvenient, is unfavorable for life-time service, have impact on applying of tcm therapy.
Summary of the invention:
The object of the invention is to the shortcoming overcoming prior art existence, for the deficiency that the Chinese and western medicine medicine of existing treatment children's adenoid vegetation exists, provide that a kind of therapeutic effect is good, easy to use, the Chinese patent medicine preparation of infant more acceptant treatment children's adenoid vegetation.
In the Chinese patent medicine preparation of the treatment children's adenoid vegetation that the present invention relates to, the weight proportion of each component is:
Adopt existing Chinese patent medicine preparation technology to make graininess, honeyed pill shape or ointment preparation according to said ratio, be used for the treatment of children's's adenoid vegetation.
Yam slice of the present invention adopts fresh Chinese yam to make, put into saline after fresh Chinese yam is cleaned peeling and soak 3-15 minute, again the Rhizoma Dioscoreae after saline soak is put into boiling water and boil 1-5 minute, then taken out by Rhizoma Dioscoreae and put into the thin slice being cut into 3-5mm after cold water is cooled to room temperature, at 50-60 DEG C, constant temperature drying makes yam slice.
Folium Mori of the present invention adopt the new fresh mulberry leaf after frost occurs, and the hot water putting into 70-80 DEG C after being cleaned by the new fresh mulberry leaf after frost occurs soaks 3-5 minute, then constant temperature drying makes dry Folium Mori at 40-50 DEG C.
The present invention, according to the pathogeny of the children's's adenoid vegetation with inflammation-related and symptomes complice, adopts the rule for the treatment of preparation of heat-clearing and toxic substances removing, invigorating the spleen to clear away damp pathogen, dissipating phlegm and removing blood stasis; Flos Lonicerae has heat-clearing and toxic substances removing, effect of removing heat from blood, and pharmacological experiment proves, Flos Lonicerae has stronger broad-spectrum antibacterial action, to carbuncle furuncle, and septicemia, upper sense tonsillitis has good effect; Fructus Forsythiae has heat-clearing and toxic substances removing, broad-spectrum antibacterial action, with Flos Lonicerae 5 with increasing antiphlogistic effects; Radix Paeoniae Rubra has effect of clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, Bulbus Fritillariae Thunbergii removing heat-phlegm, mass dissipating and swelling eliminating; Poria eliminating dampness and diuresis, is realized by strong activating the spleen pulmonary function; Semen Coicis, invigorating spleen to remove dampness, clearing away heat and discharging pus, have facilitation to cellular immunization and humoral immunization, have antiinflammatory action; Spina Gleditsiae is also known as Spina Gleditsiae, Fructus Gleditsia acupuncture, and its effect is mainly dispeled the wind and drawn out pus by applying a plaster to the affected part, and for sore and toxic, non-ulceration person has the effect of drawing out pus by applying a plaster to the affected part preferably; The circulation of qi promoting of Rhizoma Sparganii removing blood stasis, removing food stagnancy pain relieving, for the lump in the abdomen mass in the abdomen that stagnation of QI and blood, pyretic toxicity pent up; Corium Erinacei Seu Hemiechianus blood-activating analgetic; Carapax Trionycis hard masses softening and resolving, hold concurrently clearind deficient heat and nourishing YIN and clearing away heat, Concretio Silicea Bambusae removing heat-phlegm, just to the phlegm and blood stasis pathogenesis place of adenoid vegetation.The light pulvis refrigerans of Folium Mori, clear dredge wind and heat in the lung meridian again can liver heat removing through excess-heat, control the standard card of children's's adenoid vegetation heat; The gas of the flat spleen reinforcing of Rhizoma Dioscoreae is cloudy, controls again the assertive evidence that children's's adenoid vegetation insufficiency of the spleen humidogene expectorant is poly-.
Compared with prior art, the Chinese patent medicine preparation therapeutic effect made is good, proportioning science in the present invention, and medication is convenient, is beneficial to infant and takes medicine, have no side effect.
Detailed description of the invention:
Below by embodiment, the invention will be further described.
Embodiment 1:
The present embodiment extracting honeysuckle 15 grams, Fructus Forsythiae 15 grams, Bulbus Fritillariae Thunbergii 12 grams, Radix Paeoniae Rubra 12 grams, 12 grams, Poria, Semen Coicis 30 grams, Spina Gleditsiae 9 grams, Rhizoma Sparganii 6 grams, Corium Erinacei Seu Hemiechianus 6 grams, Concretio Silicea Bambusae 9 grams, Carapax Trionycis 12 grams, yam slice 15 grams and 5 grams, Folium Mori, remove the impurity in each raw material, clean and dry rear common grinding and processing becomes the fine powder of more than 100 orders, by ozone sterilization after fine powder mix homogeneously 20 minutes, prior art is adopted to make granular formulations again, granular formulations is distributed into bag, 15 grams every bag, each serving one bag, warm water delivery service, one day 3 times, continuous 5 days weekly, it within 4 weeks, is a course for the treatment of.
Embodiment 2:
The present embodiment extracting honeysuckle 30 grams, Fructus Forsythiae 20 grams, Bulbus Fritillariae Thunbergii 15 grams, Radix Paeoniae Rubra 12 grams, 15 grams, Poria, Semen Coicis 30 grams, Spina Gleditsiae 12 grams, Rhizoma Sparganii 9 grams, Corium Erinacei Seu Hemiechianus 9 grams, Concretio Silicea Bambusae 6 grams, Carapax Trionycis 9 grams, yam slice 20 grams and 7 grams, Folium Mori, remove the impurity in each raw material, clean and dry rear common grinding and processing becomes the fine powder of more than 100 orders, by ozone sterilization after fine powder mix homogeneously 20 minutes, prior art is adopted to make granular formulations again, granular formulations is distributed into bag, 15 grams every bag, each serving one bag, warm water delivery service, one day 3 times, continuous 5 days weekly, it within 4 weeks, is a course for the treatment of.
Embodiment 3:
The present embodiment extracting honeysuckle 15 grams, Fructus Forsythiae 15 grams, Bulbus Fritillariae Thunbergii 12 grams, Radix Paeoniae Rubra 12 grams, 12 grams, Poria, Semen Coicis 30 grams, Spina Gleditsiae 9 grams, Rhizoma Sparganii 6 grams, Corium Erinacei Seu Hemiechianus 6 grams, Concretio Silicea Bambusae 3 grams, Carapax Trionycis 12 grams, yam slice 20 grams and 9 grams, Folium Mori, remove the impurity in each raw material, clean and dry rear common grinding and processing becomes the fine powder of more than 100 orders, by ozone sterilization after fine powder mix homogeneously 20 minutes, add 100 grams of Mel again to mix well, technology is processed into sweet pellet-formulation routinely, every sweet pill 0.5 gram, one day 3 times, each 4-6 grain, warm water delivery service, continuous 5 days weekly, it within 4 weeks, is a course for the treatment of.
Embodiment 4:
The present embodiment extracting honeysuckle 30 grams, Fructus Forsythiae 20 grams, Bulbus Fritillariae Thunbergii 15 grams, Radix Paeoniae Rubra 12 grams, 15 grams, Poria, Semen Coicis 30 grams, Spina Gleditsiae 12 grams, Rhizoma Sparganii 9 grams, Corium Erinacei Seu Hemiechianus 12 grams, Concretio Silicea Bambusae 3 grams, Carapax Trionycis 10 grams, yam slice 18 grams and 10 grams, Folium Mori, remove the impurity in each raw material, clean and dry rear common grinding and processing becomes the fine powder of more than 100 orders, by ozone sterilization after fine powder mix homogeneously 20 minutes, add 120 grams of Mel again to mix well, technology is processed into sweet pellet-formulation routinely, every pill 0.5 gram, one day 3 times, each 4-6 grain, warm water delivery service, continuous 5 days weekly, it within 4 weeks, is a course for the treatment of.
Embodiment 5:
The present embodiment extracting honeysuckle 25 grams, Fructus Forsythiae 15 grams, Bulbus Fritillariae Thunbergii 15 grams, Radix Paeoniae Rubra 15 grams, 10 grams, Poria, Semen Coicis 25 grams, Spina Gleditsiae 10 grams, Rhizoma Sparganii 9 grams, Corium Erinacei Seu Hemiechianus 12 grams, Concretio Silicea Bambusae 3 grams, Carapax Trionycis 12 grams, yam slice 20 grams and 8 grams, Folium Mori, first remove the impurity in each raw material, clean and dry, adopt prior art each raw material to be put into water again and decoct rear filtration, the filtrate obtained is adopted common process carry out concentrated after add Mel or ointment preparation made by sugar, within one day, take 3 times, each soupspoon, continuous 5 days weekly 4 weeks is a course for the treatment of.
Embodiment 6:
The present embodiment extracting honeysuckle 25 grams, Fructus Forsythiae 15 grams, Bulbus Fritillariae Thunbergii 15 grams, Radix Paeoniae Rubra 15 grams, 10 grams, Poria, Semen Coicis 25 grams, Spina Gleditsiae 10 grams, Rhizoma Sparganii 9 grams, Corium Erinacei Seu Hemiechianus 12 grams, Concretio Silicea Bambusae 3 grams, Carapax Trionycis 12 grams, yam slice 20 grams and 6 grams, Folium Mori, first remove the impurity in each raw material, clean and dry, adopt prior art each raw material to be put into water again and decoct rear filtration, the filtrate obtained is adopted common process carry out concentrated after add Mel or ointment preparation made by sugar, within one day, take 3 times, each soupspoon, continuous 5 days weekly 4 weeks is a course for the treatment of.
Embodiment 7:
The present embodiment to 180 3-10 year children's's adenoid vegetation patient carry out observation treatment, average (3.5 ± 2.5) year; The course of disease the shortest January, the longest 2 years; Patient is divided into six groups, takes Chinese patent medicine preparation prepared by embodiment 1-6 respectively, check after treating 3 courses for the treatment of, its therapeutic outcome is as shown in table 1.
Table 1:
1st group 2nd group 3rd group 4th group 5th group 6th group
Effective 15 16 14 12 13 14
Effectively 13 12 14 15 15 13
Invalid 2 2 2 3 2 3
Wherein effective finger clinical symptoms disappears substantially, and pharyngorhinoscopy recovers obviously; Effective finger clinical symptom relief, pharyngorhinoscopy takes a turn for the better or to some extent without significant change; Invalid finger clinical symptoms is not improved, and pharyngorhinoscopy is unchanged or increase the weight of, and as can be seen from Table 1, Chinese patent medicine preparation obvious effective rate prepared by the present embodiment is 46.67%, and effective percentage is 45,56%, and therapeutic effect is obvious.

Claims (3)

1. treat a Chinese patent medicine preparation for children's's adenoid vegetation, it is characterized in that the weight proportion of each component is:
Adopt existing Chinese patent medicine preparation technology to make graininess, honeyed pill shape or ointment preparation according to said ratio, be used for the treatment of children's's adenoid vegetation.
2. treat the Chinese patent medicine preparation of children's's adenoid vegetation according to claim 1, it is characterized in that described yam slice adopts fresh Chinese yam to make, put into saline after fresh Chinese yam is cleaned peeling and soak 3-15 minute, again the Rhizoma Dioscoreae after saline soak is put into boiling water and boil 1-5 minute, then taken out by Rhizoma Dioscoreae and put into the thin slice being cut into 3-5mm after cold water is cooled to room temperature, at 50-60 DEG C, constant temperature drying makes yam slice.
3. treat the Chinese patent medicine preparation of children's's adenoid vegetation according to claim 1, it is characterized in that described Folium Mori adopt the new fresh mulberry leaf after frost occurs, the hot water putting into 70-80 DEG C after being cleaned by new fresh mulberry leaf after frost occurs soaks 3-5 minute, then constant temperature drying makes dry Folium Mori at 40-50 DEG C.
CN201510026300.1A 2015-01-20 2015-01-20 Chinese patent medicine preparation used for treating pediatric adenoidal hypertrophy Pending CN104491626A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102138977A (en) * 2011-03-16 2011-08-03 于海燕 Baizhi Xiner decoction for adenoid vegetation
CN103800580A (en) * 2013-12-27 2014-05-21 芜湖乐锐思信息咨询有限公司 Traditional Chinese medicinal prescription for treating adenoidal hypertrophy and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102138977A (en) * 2011-03-16 2011-08-03 于海燕 Baizhi Xiner decoction for adenoid vegetation
CN103800580A (en) * 2013-12-27 2014-05-21 芜湖乐锐思信息咨询有限公司 Traditional Chinese medicinal prescription for treating adenoidal hypertrophy and preparation method thereof

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冯兵勇等: "中医药治疗小儿腺样体肥大的体会", 《中医儿科杂志》 *
马晋彤: "保守治疗儿童鼾症30例临床观察", 《长春中医药大学学报》 *

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Application publication date: 20150408