CN104491278A - Traditional Chinese medicinal composition for treating leucoderma due to qi stagnation and blood stasis - Google Patents
Traditional Chinese medicinal composition for treating leucoderma due to qi stagnation and blood stasis Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/37—Celastraceae (Staff-tree or Bittersweet family), e.g. tripterygium or spindletree
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A61K36/88—Liliopsida (monocotyledons)
- A61K36/89—Cyperaceae (Sedge family)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
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- A61K9/00—Medicinal preparations characterised by special physical form
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- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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Abstract
The invention discloses an oral traditional Chinese medicinal composition for treating leucoderma due to qi stagnation and blood stasis. The oral traditional Chinese medicinal composition is formed by combining seven medicines including fiveleaf akebia fruit, rose, Cyperus Rotundus L, native copper (calcined), campsis grandiflora, radix paeoniae rubrathe and Ligusticum wallichii, etc. according to a certain weight ratio, has effects of soothing the liver, rectifying qi and promoting blood circulation to remove blood stasis, and has excellent clinical effects of treating leucoderma due to qi stagnation and blood stasis. The invention also discloses an external traditional Chinese medicinal composition for treating leucoderma due to qi stagnation and blood stasis. The external traditional Chinese medicinal composition is composed of two medicines, including ginger and ramulus euonyrni, etc., is made into medicinal liquor for external use, and has a good effect when used along with the oral traditional Chinese medicinal composition.
Description
Technical field
The present invention relates to the leukodermic Chinese medicine composition of one treatment qi stagnation and blood stasis type.
Background technology
Vitiligo is acquired skin pigment depigmentation disease a kind of common day after tomorrow, show as skin limitation or general property depigmentation speckle, be tryrosinase system in the melanin due to illing skin and hair follicle hypofunction caused by, modern medicine due to etiology unknown so easily examine and refractory.Although this disease does not bring sensual misery to patient, but the skin lesion due to primary disease directly affects the outward appearance appearance of people, great stress and psychological burden is brought to patient, many negative factors are brought to the aspect such as life, work, social activity of patient, thus have impact on the quality of life of patient.But, to the treatment of primary disease, there is no definite effective Therapeutic Method up to now
The etiology and pathogenesis of Chinese medicine to primary disease has suitable research.Clear Wang Qingren errors in Medicine Corrected speech: " vitiligo, blood stasis is in flesh side ", and intend TONGQIAOHUOXUE Decoction and control it, full side is made up of Radix Paeoniae Rubra, Rhizoma Chuanxiong, Semen Persicae, Fructus Jujubae, Flos Carthami, old Herba Alii fistulosi, fresh ginger, Moschus." taking three, five pairs can not be careless and sloppy, then takes 30 pairs and can fully recover from an illness." clearly propose one of leukodermic pattern of syndrome: qi stagnation and blood stasis type.
Summary of the invention
In order to solve the problem, the present invention proposes one and treats the leukodermic Chinese medicine composition of qi stagnation and blood stasis type, is made up of for oral administration and external two kinds of compositionss.Described internal composition is made up of the crude drug of following weight portion:
Fructus Akebiae 6 ~ 24 parts, Flos Rosae Rugosae 3 ~ 12 parts, Rhizoma Cyperi 6 ~ 24 parts, Pyritum (forging) 10 ~ 30 parts, Flos Campsis 3 ~ 20 parts, Radix Paeoniae Rubra 1 ~ 30 part, Rhizoma Chuanxiong 3 ~ 20 parts;
Described topical composition is made up of the crude drug of following weight portion:
3 ~ 20 parts, Rhizoma Zingiberis Recens, Ramulus Euonymi 4.5 ~ 18 parts.
The each amounts of components of part for oral administration in following weight parts scope can also be: Fructus Akebiae 9 ~ 18 parts, Flos Rosae Rugosae 6 ~ 10 parts, Rhizoma Cyperi 9 ~ 18 parts, Pyritum (forging) 12 ~ 15 parts, Flos Campsis 6 ~ 18 parts, Radix Paeoniae Rubra 3 ~ 25 parts, Rhizoma Chuanxiong 6 ~ 18 parts.。
Be preferably: Fructus Akebiae 12 parts, Flos Rosae Rugosae 9 parts, Rhizoma Cyperi 12 parts, Pyritum (forging) 15 parts, Flos Campsis 10 parts, Radix Paeoniae Rubra 15 parts, Rhizoma Chuanxiong 10 parts.
The each amounts of components of external part in following weight parts scope can also be: 6 ~ 18 parts, Rhizoma Zingiberis Recens, Ramulus Euonymi 6 ~ 15 parts.
Be preferably: 10 parts, Rhizoma Zingiberis Recens, Ramulus Euonymi 9 parts.
The present invention is for oral administration selects 7 herbal medicines such as Fructus Akebiae, Flos Rosae Rugosae, Rhizoma Cyperi, Pyritum (forging), Flos Campsis, Radix Paeoniae Rubra, Rhizoma Chuanxiong to carry out prescription according to the principle of differentiation of tcm.Fructus Akebiae hardship is flat, returns liver stomach warp, depressed liver-energy dispersing and QI regulating eliminating stagnation; The sweet micro-bitter temperature of Flos Rosae Rugosae, returns liver spleen channel, promoting QI circulation for relieving depression, and blood dissipating blood stasis; The pungent micro-hardship of Rhizoma Cyperi is micro-sweet flat, returns liver tri-jiao channel, depressed liver-energy dispersing and QI regulating, menstruction regulating and pain relieving; Pyritum is pungent flat, and return Liver Channel, eliminating stasis to stop pain, synthetism are cured the wound; Flos Campsis is pungent to be slightly cold, and returns liver pericardium channel, promoting blood circulation and breaking stagnation, cooling blood, expelling wind; Radix Paeoniae Rubra hardship is slightly cold, and returns Liver Channel, clearing away heat and cooling blood, stasis-dispelling and pain-killing; The pungent temperature of Rhizoma Chuanxiong, returns liver and gall pericardium channel, blood-activating and qi-promoting, wind-expelling pain-stopping.All medicines share, and gather effect of depressed liver-energy dispersing and QI regulating, blood circulation promoting and blood stasis dispelling altogether.
Topical composition, comprises Rhizoma Zingiberis Recens, Ramulus Euonymi two herbal medicine.The pungent temperature of Rhizoma Zingiberis Recens, enters liver and gall lung meridian, has the merit of soothing the liver removing blood stasis; Ramulus Euonymi bitter cold, enters Liver Channel, the effect that the removing blood stasis that can gather stimulates the menstrual flow
,two medicines are harmonious, and make medicated wine external, gather effect of eliminating blood stasis and removing ecchymoses altogether.
Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional oral preparations, such as: decoction, medicinal tea, powder, pill, tablet, oral liquid, unguentum, capsule etc., the present invention preferably selects powder.
The present invention selects natural drug to be raw material, and each component meets pharmaceutical control law regulation.Utilize the comprehensive function treatment vitiligo of each taste Chinese medicine, without chemical addition agent, harmless to human non-toxic.
Detailed description of the invention
The present embodiment is described as follows:
Internal composition takes raw material (kilogram) by following proportioning
1, Fructus Akebiae 6, Flos Rosae Rugosae 3, Rhizoma Cyperi 6, Pyritum (forging) 10, Flos Campsis 3, Radix Paeoniae Rubra 1, Rhizoma Chuanxiong 3;
2, Fructus Akebiae 24, Flos Rosae Rugosae 12, Rhizoma Cyperi 24, Pyritum (forging) 30, Flos Campsis 20, Radix Paeoniae Rubra 30, Rhizoma Chuanxiong 20;
3, Fructus Akebiae 9, Flos Rosae Rugosae 6, Rhizoma Cyperi 9, Pyritum (forging) 12, Flos Campsis 6, Radix Paeoniae Rubra 3, Rhizoma Chuanxiong 6;
4, Fructus Akebiae 18, Flos Rosae Rugosae 10, Rhizoma Cyperi 18, Pyritum (forging) 15, Flos Campsis 18, Radix Paeoniae Rubra 25, Rhizoma Chuanxiong 18;
5, Fructus Akebiae 12, Flos Rosae Rugosae 9, Rhizoma Cyperi 12, Pyritum (forging) 15, Flos Campsis 10, Radix Paeoniae Rubra 15, Rhizoma Chuanxiong 10.
Production method is as follows: pulverized respectively by each herbal medicine, and after crossing 80-120 mesh sieve, all medicines mix by weight ratio and can obtain.
Topical composition takes raw material (gram) by following proportioning
6, Rhizoma Zingiberis Recens 3, Ramulus Euonymi 4.5;
7, Rhizoma Zingiberis Recens 20, Ramulus Euonymi 18;
8, Rhizoma Zingiberis Recens 6, Ramulus Euonymi 6;
9, Rhizoma Zingiberis Recens 18, Ramulus Euonymi 15;
10, Rhizoma Zingiberis Recens 10, Ramulus Euonymi 9.
Production method is as follows: got it filled by above weight proportion by two herbal medicines, be placed in bronze, brass or copper ware, with the appropriate amount of ethanol lixiviate of 70%.Get leachate 100ml and get final product, Rhizoma Zingiberis Recens is continued to employ.
Using method: dip in leachate affected part of exterior coating with Rhizoma Zingiberis Recens in side, repeatedly wipe examination, to affected part micro-red.Every day 3 times, after medicine, affected part irradiates 15 minutes in the sunlight
For showing that Chinese medicine of the present invention is to the leukodermic therapeutic effect of qi stagnation and blood stasis type, the present invention have passed through 60 routine system clinical observations: patient 60 example, wherein man 24 example, female 36 example; 18 ~ 65 years old age, wherein less than 20 years old person 4 example, 26 examples between 21 ~ 30 years old, 12 examples between 31 ~ 40 years old, 10 examples between 41 ~ 50 years old, 8 examples between 51 ~ 65 years old.Patients is: white macula differs in size, and is speckle or lamellar, clear-cut margin, and color and luster is sometimes bright sometimes dark, often passes through change with feelings and aggravates, without fixing predilection site.With pass belch uncomfortable in chest, distending pain in the chest and hypochondrium, the impetuous irritability of disposition, purplish tongue, has petechia ecchymosis, and tongue is white, stringy pulse or puckery.For the effect of ruling together inside and outside verifying, during clinical observation, 60 routine patients are divided into three groups at random, first group of 20 people only takes oral medicine, and second group of 20 people only uses medicine for external use, and the 3rd group of 20 people are for oral administration to carry out with external simultaneously.
Instructions of taking: internal composition adopts the Chinese medicine in embodiment 5, and make powder, twice daily, each 9 grams three months is a course for the treatment of.Topical composition adopts the Chinese medicine in embodiment 10 to make medicated wine, dips in wine and is coated with outward, day three times with the Rhizoma Zingiberis Recens in medicated wine, Exposure to Sunlight 15 minutes after being coated with.
Curative effect determinate standard
According to " vitiligo Clinical typing and the criterion of therapeutical effect " of Dermatology Professional Committee of CAIM (Chinese Association Of Integrative Medicine) pigment disease group in combination of Chinese and Western medicine skin pigment disease investigation club of in December, 2003 China revision.Recovery from illness: white macula disappears completely, recovers normal skin tone.Effective: white macula reduces, recover normal skin tone more than 50%.Effective: white macula reduces, recover normal skin tone 10% ~ 49%.Invalid: white macula reduces, recover normal skin tone less than 10%.
Result
After the course for the treatment of, in first group of 20 routine patient, effective 7 examples, effective 8 examples, invalid 5 examples, total effective rate 75%; In the second routine patient in composition portion 20, effective 6 examples, effective 8 examples, invalid 6 examples, total effective rate 70%; In the 3rd routine patient in composition portion 20, effective 9 examples, effective 9 examples, invalid 2 examples, total effective rate 90%.
Claims (4)
1. treat the leukodermic Chinese medicine composition of qi stagnation and blood stasis type, it is characterized in that: be made up of for oral administration and external two kinds of compositionss,
Described internal composition is made up of the crude drug of following weight portion:
Fructus Akebiae 6 ~ 24 parts, Flos Rosae Rugosae 3 ~ 12 parts, Rhizoma Cyperi 6 ~ 24 parts, Pyritum (forging) 10 ~ 30 parts, Flos Campsis 3 ~ 20 parts, Radix Paeoniae Rubra 1 ~ 30 part, Rhizoma Chuanxiong 3 ~ 20 parts;
Described topical composition is made up of the crude drug of following weight portion:
3 ~ 20 parts, Rhizoma Zingiberis Recens, Ramulus Euonymi 4.5 ~ 18 parts.
2. the leukodermic Chinese medicine composition for the treatment of qi stagnation and blood stasis type according to claim 1, is characterized in that described internal composition is made up of the crude drug of following weight portion:
Fructus Akebiae 9 ~ 18 parts, Flos Rosae Rugosae 6 ~ 10 parts, Rhizoma Cyperi 9 ~ 18 parts, Pyritum (forging) 12 ~ 15 parts, Flos Campsis 6 ~ 18 parts, Radix Paeoniae Rubra 3 ~ 25 parts, Rhizoma Chuanxiong 6 ~ 18 parts;
Described topical composition is mainly made up of the crude drug of following weight portion: 6 ~ 18 parts, Rhizoma Zingiberis Recens, Ramulus Euonymi 6 ~ 15 parts.
3. the leukodermic Chinese medicine composition for the treatment of qi stagnation and blood stasis type according to claim 1, is characterized in that described internal composition is made up of the crude drug of following weight portion:
Fructus Akebiae 12 parts, Flos Rosae Rugosae 9 parts, Rhizoma Cyperi 12 parts, Pyritum (forging) 15 parts, Flos Campsis 10 parts, Radix Paeoniae Rubra 15 parts, Rhizoma Chuanxiong 10 parts;
Described topical composition is made up of the crude drug of following weight portion:
10 parts, Rhizoma Zingiberis Recens, Ramulus Euonymi 9 parts.
4. the leukodermic Chinese medicine composition for the treatment of qi stagnation and blood stasis type according to claim 1,2 or 3, is characterized in that the dosage form of described internal composition is powder, and the dosage form of described medicine for external use is medicated wine.
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106344687A (en) * | 2016-11-09 | 2017-01-25 | 徐峰 | White spot repair liquid |
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CN102038819A (en) * | 2009-10-15 | 2011-05-04 | 吴翠萍 | Decoction medicine for treating vitligo |
CN102366468A (en) * | 2011-09-04 | 2012-03-07 | 成都绿迪科技有限公司 | Traditional Chinese medicine for treating vitiligo |
CN103381264A (en) * | 2012-05-06 | 2013-11-06 | 田荣侠 | Leucoderma oral medicament and preparation method thereof |
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2014
- 2014-11-23 CN CN201410677618.1A patent/CN104491278A/en active Pending
Patent Citations (3)
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CN102038819A (en) * | 2009-10-15 | 2011-05-04 | 吴翠萍 | Decoction medicine for treating vitligo |
CN102366468A (en) * | 2011-09-04 | 2012-03-07 | 成都绿迪科技有限公司 | Traditional Chinese medicine for treating vitiligo |
CN103381264A (en) * | 2012-05-06 | 2013-11-06 | 田荣侠 | Leucoderma oral medicament and preparation method thereof |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN106344687A (en) * | 2016-11-09 | 2017-01-25 | 徐峰 | White spot repair liquid |
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