CN1044758A - Intrauterine contraceptive device - Google Patents
Intrauterine contraceptive device Download PDFInfo
- Publication number
- CN1044758A CN1044758A CN90100193A CN90100193A CN1044758A CN 1044758 A CN1044758 A CN 1044758A CN 90100193 A CN90100193 A CN 90100193A CN 90100193 A CN90100193 A CN 90100193A CN 1044758 A CN1044758 A CN 1044758A
- Authority
- CN
- China
- Prior art keywords
- main body
- active main
- metal
- intrauterine
- contraceptive
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
- A61F6/06—Contraceptive devices; Pessaries; Applicators therefor for use by females
- A61F6/14—Contraceptive devices; Pessaries; Applicators therefor for use by females intra-uterine type
- A61F6/142—Wirelike structures, e.g. loops, rings, spirals
- A61F6/144—Wirelike structures, e.g. loops, rings, spirals with T-configuration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
- A61F6/06—Contraceptive devices; Pessaries; Applicators therefor for use by females
- A61F6/14—Contraceptive devices; Pessaries; Applicators therefor for use by females intra-uterine type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0039—Devices retained in the uterus for a prolonged period, e.g. intrauterine devices for contraception
Landscapes
- Health & Medical Sciences (AREA)
- Reproductive Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention relates to a kind of intrauterine contraceptive device, it comprises an active main body (2) with the active metallics of contraception, is supported in the carrying device (1) of this active main body of intrauterine (2).Essence of the present invention is to be formed at intrauterine device by two kinds of metal active main body (2) at least a kind of battery of complexity within the border.
Description
The present invention relates to a kind of intrauterine contraceptive device, it comprises by having the carrying device that the active metallics of contraception active main body that constitutes and the biologically inert material that is supported in the domestic active main body of intrauterine device are made, wherein carrying device normally is made of plastics, and is linking an indicatrix.
For many years, known the contraceptive effect of some intrauterine device (IUD).Used the intrauterine device (IUD) of making by suitable plastic from the end of the sixties.When intrauterine device (IUD) can be used, rise and in wide scope, select difformity, configuration and material.
The evolution of intrauterine contraceptive device can be divided into three periods: be to be sign (referring to US-PS3,937,217) to use the suitable plastic goods their first period; Be perfect period second period by steroid class h substance; It is characterized in that introducing the copper that is used to prepare active main body the 3rd period.Intrauterine device (IUD) based on copper comprises the carrying device of normally being made the T type by plastics (as: polyethylene) material, and active main body is made the copper coil that contacts with carrying device, and is fixed on indicatrix on the carrying device.Most applications, active main body are that a coil-like element and indicatrix are the line of the flexibility of plastics (as: polyamide) system.
The known contraceptive effect that comprises the intrauterine contraceptive device of copper coil be much higher than need not any active substance preparation device.This understanding is to be based upon on the investigation basis of different systems.One in them is in Orvosi Hetilap(Hungary medicine weekly 2237,129., 1988 Hungary by I.Batar) report.Intrauterine contraceptive device (Maltioad Cu 250 model) with copper coil system relatively is effectively with those intrauterine contraceptive device without any active substance (be referred to as the Szontagh's device, Hungary produces), rather than invalid.By calculating C.Tietze and S, Lewit(Stud, in Fam.Plann., 35,4. that, 1973) quote and put into practice received so-called netto accumulation terminal rate (netto cumulative terminaion rates) in the world and analyze quantitative data: this effectiveness is based on that 100 numbers with this intrauterine contraceptive device pregnant woman in the cycle in 1 year measure.Its corresponding data are that Multiload Cu250 device is 2.2, and the Szontagh's device is 3.9, and first kind of device provides higher contraception safety than second device.In the article of I.Batar, can find not analyze the advantage of the technical characterictic of this device.
In the above-mentioned article of mentioning, also reported continuous about 10 years cycle of clinical observation.Comprise that the intrauterine contraceptive device with the active main body of copper coil system is used to 1446 women, so-called cumulative pregnancy rate is 6.9.Because in 88 women's pregnancies of viewing duration, its ineffectivity is up to 6.1%.Other data in literature (drawing freely: population report, volume X, 4., B103 to B135,1985, Baltimore USA) shows similar ineffectivity.Investigate some Latin American countries and to draw following characteristic: adopting women's pregnancy rate of the intrauterine contraceptive device that comprises copper is 5%; Adopting the women of oral contraception Chinese medicine usually is 8%; Women in adopting mechanism's contraception (condom) is 18%, and risk women is 40%.
1987, U.S. department of obstetrics and gynecology expert S.G.Kaal proposition had become the imagination (Dobbs Ferry, New York USA) that sperm lost efficacy as everyone knows by the effect of weak current in uterus.
These investigation have drawn nonvolatil evidence: promptly the contraception effectiveness of the known intrauterine contraceptive device of the active main body that forms with copper coil is 94 to 95%, and this level 100% relatively is lower level with what be perfectly safe.Therefore, improving its effectiveness extremely needs.
The further shortcoming of known intrauterine contraceptive device is the slowly dissolving of copper product of active main body, and final splinter during being placed in the human body, and the copper coil of this fracture may endanger tissue, and shortens life cycle.For avoiding the influence of these shortcomings, United States Patent (USP) 4351326 suggestions prepare active main body the copper coil form that has by the metal core more valuable than copper.Schering AG(FRG) company has produced such intrauterine contraceptive device, called after NOVA T, and the fuse of copper band wherein is made from silver.By this way, the required smooth time than fine copper circle of the surface of intrauterine contraceptive device maintenance is long.
Comprise copper intrauterine contraceptive device contraceptive effect by owing to since copper cause.The course of dissolution of copper, that is: the speed of contraception device generation copper ion is uneven, therefore, known devices is to the physiological process of human body (that is: the change of the activity of enzyme process, glycogen metabolism, estrogenic absorption, uterus muscle, fluid component etc.), the implantation of germ cell, has unsettled influence to preventing conceived mechanism.
The present invention plans to create a kind of intrauterine contraceptive device of the high contraception efficient (reaching 99% at least) based on metallics.Intrauterine contraceptive device provided by the invention can keep its original form and guarantee evenly to discharge the ion with contraceptive effect between the whole operating period.
The present invention is based on following understanding, that is: the active main body of intrauterine contraceptive device should be made a kind of metal and another kind of metal forms a kind of battery within the border at intrauterine device by the suitable metal composites that contains two kinds of metals at least.
Based on above-mentioned cognition, a kind of intrauterine contraceptive device is just invented, it comprises that this active main body is to be formed in the battery that forms a complexity in the environment of uterus by the metallics that comprises at least two kinds of metals according to the present invention by having the carrying device of the active main body formed of the active metallics of contraception with the biologically inert material system that is used to be supported in the domestic active main body of intrauterine device.The advantage of this active main body is that the alloy that is at least at least two kinds of metals makes.
These battery great majority are made up of copper-Jin or copper-zinc-silver alloy.Certainly, other alloy also can adopt, and especially prepares needed active main body from copper and at least a higher electropositive metal, when the negative electrode of copper formation battery, and other metal, for example: gold or silver just constitute its anode.Some other metal composites is: nickel and gold; Copper, silver and zinc; Silver and cadmium; Silver and palladium.
The principal advantages of intrauterine contraceptive device of the present invention be this active main body comprise one little, in most cases atomic battery, the ion of negative electrode there, ordinary circumstance are that copper ion can be more dissolved than the higher concentration of the intrauterine contraceptive device of Known designs.
The active main body of intrauterine contraceptive device provided by the invention can preferably be made the shape of the circle of the mixture composition that comprises multiple metal (as: copper and zinc, silver), and described mixture also can constitute alloy as required.In this situation, multiple metal can exist with ionic species with in the quantity that controls, thereby the potential difference between the battery electrode progressively increases, and based on making the deactivated contraception effectiveness of sperm also along with increase.
Another preferred embodiment of active main body wherein can be used with one or more tube elements for making tubular shape, and under the situation of a plurality of tube elements, they can be separated by loop member.
The further superiority of intrauterine contraceptive device of the present invention and characteristics will also be described in more detail in conjunction with the accompanying drawings by some preferable specific embodiments of this device.Accompanying drawing is as follows:
Fig. 1 is the sketch map of contraceptive device with cast active main body,
Fig. 2 is the sketch map of intrauterine contraceptive device that comprises the active main body of the pipe shape of being made by Alloy Foil,
Fig. 3 is the sketch map of the intrauterine contraceptive device of the active main body of two tubular shape having and three cyclic elements.
Intrauterine contraceptive device of the present invention shown in Fig. 1,2 and 3 comprises the carrying device 1 that plastics are made, bring into play required activity (that is: make the domestic sperm inactivation of intrauterine device) active main body 2 and with carrying device 1 banded indicatrix 3.
The active main body 2 of intrauterine contraceptive device of the present invention is looped around carrying device 2(Fig. 1 by producing coil 4 usually) two bars 10 on.Coil 4 also can be made bifilar helix from a wires by known mechanical technique.Simple coil or bifilar helix; That is: can provide high surf zone by single line around other bifilar helix of single line preparation from a wires.
Fig. 2 illustrates the another kind of probability that active main body 2 is shaped, and wherein active main body 2 comprises around two bars 10 and 11 from encircling 10 pipes 5 until arm 12 and 13 starting ends.This pipe 5 can form tubular unit and airtight production by metal forming, that is: by the connecting line to another side welds generation along one side of metal forming.
Can also see further preferable probability in Fig. 3, wherein active main body 2 can be divided into all many parts: bar 10 and 11 partly is set at tube element 7 and 6 encirclements of ring wherein.Further, ring 8 places the free end of corresponding arm 12 and 13.This scheme comprises having the heteropical surface layer paper tinsel of wanting that has that comprises the small or little battery that two kinds of metals form at least required for the present invention and the element of metal wire class is particularly advantageous to solving active main body 2.Two kinds or multiple metal composites be for coil 4 and pipe 5, at whole volume or also be necessary on the outer surface at least two kinds of metals at least.
In general, active main body 2 comprise copper and at least a higher electropositive other metal as: golden or silver-colored.These metals not only can form mixture but also can be a kind of alloy.Also can adopt the third and other metals, in this case, use the battery of different voltage series.In the following a series of embodiment that provide, listed other preferable selection of preparation active main body 2, yet these embodiment limit the scope of the invention.
In the environment of uterus, contraceptive device of the present invention forms the battery of the complexity with electrode in active main body.This electrolyte is the biofluid in uterus.If this active main body is to be to be in by first kind of metal such as copper formed " island " (isles) and negative electrode is the part that constitutes at noble metal such as gold by first kind of given metal as the rule indication anode of: the electrochemical corrosion that copper and more valuable metals like gold are made.Course of dissolution causes first kind of metal to move from active main body 2, and in fact negative electrode does not have to change still in their origin-location, and their cracking can not be observed.In battery, first metal ion species promptly: the concentration of copper ion is higher than the concentration in environment of known intrauterine contraceptive device.
Because adopt the mixture or the alloy that comprise at least two kinds of metals, the active ion dispose procedure of contraception of assurance apparatus of the present invention becomes can be controlled, negative electrode or anode " island " have guaranteed that active main body 2 keeps original shape, thereby have avoided active main body cracked of known devices and cause problem coarse, that the outer surface that breaks is relevant.The mixture of active main body 2 or the composition of alloy can be selected more widely.
Intrauterine contraceptive device of the present invention is used according to following method; Little or the small battery that metal component by active main body 2 produces not only can discharge needed active ion in the environment of uterus, and can produce an electric field.Therefore, the contraception activity based on chemical effect can improve greatly by electric field.Know that sperm has electricity to be changed, according to their variation, this just causes them to move to the negative electrode and the anode of battery separately.Therefore the inactivation of sperm demonstrates more effective than known contraceptive device.
The further advantage of intrauterine contraceptive device of the present invention is, be accompanied by the stimulation of sexual intercourse process, when human body temperature surpassed normal level, the ionic intensity that discharges in the battery had increased, and this is especially required to cause the active raising of intrauterine contraceptive device of the present invention.
The active main body 2 of intrauterine contraceptive device of the present invention is coil 4(Fig. 1), it is made up of 85 parts of copper and 15 parts of gold.This coil 4 is by a lead coiled, and is looped around on the carrying device 1 that polyethylene makes.This carrying device 1 is linking polyamide thread 3.
The active main body 2 of intrauterine contraceptive device of the present invention is coil 4(Fig. 1), it is by the alloy composition that comprises 30 parts of zinc and 70 parts of copper.This coil 4 is by a lead coiled, and is looped around on the carrying device 1 that polyethylene makes.This carrying device 1 is linking polyamide thread 3.
The active main body 2 of intrauterine contraceptive device of the present invention is coil 4(Fig. 1), it is by the alloy composition that comprises 40 parts of palladiums and 70 parts of silver.This coil 4 is to be become by a wire-wound, and is looped around on the carrying device 1 that polyethylene makes.This carrying device 1 is linking polyamide thread 3.
Embodiment 4
The active main body 2 of intrauterine contraceptive device of the present invention is coil 4(Fig. 1), it is by the alloy composition that comprises 18 parts of nickel and 82 parts of gold.This coil 4 is by a lead coiled, and is looped around on the carrying device 1 that polyethylene makes.This carrying device 1 is linking polyamide thread 3.
Active main body 2 pipe 5(Fig. 2 of intrauterine contraceptive device of the present invention) for making by the alloy of 40 parts of copper, 25 parts of silver and 35 parts of zinc.Pipe 5 is to be made by welding by metal forming.The carrying device 5 that plastics are made is linking polyamide thread 3.
Embodiment 6
The active main body 2 of intrauterine contraceptive device of the present invention is for by copper cash with have the Copper Foil that comprises gold and silver-colored blended surface layer and make.This copper cash is made the shape of ring 6 and 8, and this Copper Foil sealing constitutes tube element 7(Fig. 3).The carrying device 1 that plastics are made is linking the line 3 of flexiplast.
The serve as reasons lead and the paper tinsel that comprise 10 parts of cadmic alloys of 90 parts of silver of the active main body 2 of intrauterine contraceptive device of the present invention made.This lead is made the shape of ring 6 and 8, and this paper tinsel sealing constitutes tube element (7) (Fig. 3).The carrying device 1 that plastics are made is linking the line 3 of flexiplast.
Intrauterine contraceptive device of the present invention tests under near physiological condition, and according to the observation, its useful life surpasses 20 years, and contraception validity is at least up to 99%. This device can use with the method for all fours of known devices.
Claims (14)
1, a kind of intrauterine contraceptive device, comprise the active main body that (a) a kind of active metallics of practising contraception is made, (b) carrying device of the described active main body in uterus of support is characterized in that described active main body (2) is formed in the battery that described intrauterine device forms a kind of complexity within the border by two kinds of metals at least.
2, contraceptive device as claimed in claim 1 is characterized in that described active main body (2) contains the alloy of being made up of two kinds of metals at least at least in part.
3, contraceptive device as claimed in claim 1 or 2 is characterized in that described active main body (2) is to be selected from zinc, copper, nickel, silver and cadmic group a kind of metal and mixture and/or the alloy composition of making than at least a more precious metal of the metal that is selected from known group by comprising at least.
4, contraceptive device as claimed in claim 3 is characterized in that described more valuable metal is to be selected to comprise silver, gold and palladic group.
5,, it is characterized in that described mixture and/or alloy comprise zinc as claim 3 or 4 described contraceptive devices.
6,, it is characterized in that described active main body (2) makes the form (4) of circle on described carrying device (1) as each described each contraceptive device of claim 1 to 5.
7,, it is characterized in that described active main body (2) makes the form (5,7) of tube element at least in part and prolong the bar (10,11) of described carrying device (1) and be provided with as each described contraceptive device of claim 1 to 6.
8, contraceptive device as claimed in claim 7 is characterized in that described active main body (2) comprises at least two pipe single-pieces (7), is looped around on the described carrying device (1).
9, contraceptive device as claimed in claim 8, it is characterized in that described active main body (2) comprises two tube elements (6) and three rings (6,8), one of them ring is arranged on the described bar (10 of described carrying device (1), 11) and two rings place on the arm (12,13) of carrying device (1).
10, a kind of intrauterine contraceptive device, comprise that (a) has the active main body that a kind of active metallics of practising contraception is made, and the carrying device that (b) is supported in intrauterine described active main body, described carrying device is made of plastics, it is characterized in that described active main body (2) is to be selected to comprise zinc, copper, cadmium, a kind of metal of the group of nickel and silver and at least a current potential are higher than from the metallic element of the described group of metal of selecting to be made, described metal forms mixture and/or alloy, and the described mixture of wherein said metal and/or alloy are at the domestic battery that constitutes a kind of complexity of intrauterine device.
11, contraceptive device as claimed in claim 10 is characterized in that described metallic element comprises at least a metal that is selected from the group of silver, palladium and gold.
12, as claim 10 or 11 described contraceptive devices, the described metal that it is characterized in that being selected from described group is a copper, and described hardware is to make with other the metal that electropositive is lower than copper, and described further metal is a zinc.
13,, it is characterized in that described active main body (2) is circle (4) and/or at least a pipe single-piece (5,7) at claim 11 or 12 described contraceptive devices.
14, contraceptive device as claimed in claim 13 is characterized in that described active main body (2) comprises the ring (6,8) that is looped around described carrying device (1) at least.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU89569A HU200905B (en) | 1989-02-07 | 1989-02-07 | Electrochemical contraceptive device |
HU569/89 | 1989-02-07 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1044758A true CN1044758A (en) | 1990-08-22 |
CN1018521B CN1018521B (en) | 1992-10-07 |
Family
ID=10950196
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN90100193A Expired CN1018521B (en) | 1989-02-07 | 1990-01-08 | Intrauterine contraceptive device |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0462110A1 (en) |
KR (1) | KR910700032A (en) |
CN (1) | CN1018521B (en) |
AU (1) | AU4941590A (en) |
BR (1) | BR9007098A (en) |
CS (1) | CS30890A2 (en) |
DD (1) | DD291243A5 (en) |
DE (1) | DE4090201T (en) |
FI (1) | FI913721A0 (en) |
HU (1) | HU200905B (en) |
PL (1) | PL162833B1 (en) |
RO (1) | RO107542B1 (en) |
WO (1) | WO1990009158A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112999433A (en) * | 2021-02-23 | 2021-06-22 | 吴江永元生物科技有限公司 | Cu-Zn composite material intrauterine device and preparation method thereof |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4311812A1 (en) * | 1993-04-13 | 1995-01-26 | Christian Kossack | Device for the electrolytic inactivation of sperm for use in men |
DE19542386A1 (en) * | 1995-11-01 | 1997-05-15 | Hamann Bernd Dr Med Habil | Intrauterine pessary |
US7073504B2 (en) | 1996-12-18 | 2006-07-11 | Ams Research Corporation | Contraceptive system and method of use |
BE1011714A3 (en) * | 1998-01-20 | 1999-12-07 | Wildemeersch Dirk | Increased efficacy intra-uterine device |
AU2005209844B2 (en) | 2004-02-02 | 2010-07-08 | Bayer Essure, Inc. | Contraceptive with permeable and impermeable components |
AU2005209871B2 (en) * | 2004-02-02 | 2010-06-17 | Conceptus, Inc. | Enhancing tissue ingrowth for contraception |
FI123188B (en) * | 2005-04-05 | 2012-12-14 | Bayer Oy | Ultrasonically detectable intrauterine system |
WO2010112095A1 (en) * | 2009-04-03 | 2010-10-07 | Bio Material Systems Nv/Sa | Improvement to intrauterine copper contraceptive devices |
ITBO20110229A1 (en) * | 2011-04-28 | 2012-10-29 | Alberto Mazzanti | INTRAUTERINO DISCUSSION (IUD) |
US9265652B2 (en) | 2012-08-14 | 2016-02-23 | Contramed, Llc | Intrauterine contraceptive device |
US9089418B2 (en) | 2012-08-14 | 2015-07-28 | Contramed, Llc | Intrauterine contraceptive device |
DK2945580T3 (en) * | 2013-01-17 | 2020-07-27 | Pat&Co Bvba | COPPER RELEASE HYBRID INTRAUTERIN DEVICE WITH HOLDING ARM RELATED TO FRAMELESS BODY |
US10918516B2 (en) | 2013-10-14 | 2021-02-16 | Sebela Vlc Limited | Intrauterine device with controlled copper ion elution |
US10188546B2 (en) | 2013-10-14 | 2019-01-29 | Sebela Vlc Limited | Intrauterine device with controlled copper ion elution |
US9180040B2 (en) | 2013-10-18 | 2015-11-10 | Contramed, Llc | Intrauterine device with retrieval thread |
SI24779A (en) * | 2014-08-28 | 2016-02-29 | CABALLUS CARNIOLUS & AMSTERDAMUS, veterinarsko tehnološki center in trgovina, uvoz - izvoz d.o.o. | Intrauterine device for humans and animals and the process for producing the same |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2758037A1 (en) * | 1977-12-24 | 1979-06-28 | Kurt Dr Med Herten | Pessary and applicator - with application rod coupled by claw clips to pessary stem ring |
ES239677Y (en) * | 1978-11-23 | 1979-06-16 | Sopena Quesada Angel | INTRAUTERINE SPERM |
FI59720C (en) * | 1980-04-02 | 1981-10-12 | Outokumpu Oy | COUPLING FOER LIVMODERINLAEGG SAMT FOERFARANDE FOER FRAMSTAELLNING AV DENSAMMA |
FR2536987B1 (en) * | 1982-07-19 | 1985-10-31 | Serimed | ENDO-UTERINE STERILET FOR ANIMALS SUCH AS DOGS |
-
1989
- 1989-02-07 HU HU89569A patent/HU200905B/en not_active IP Right Cessation
- 1989-12-29 DD DD89336761A patent/DD291243A5/en not_active IP Right Cessation
-
1990
- 1990-01-08 CN CN90100193A patent/CN1018521B/en not_active Expired
- 1990-01-22 CS CS90308A patent/CS30890A2/en unknown
- 1990-01-23 RO RO148177A patent/RO107542B1/en unknown
- 1990-01-23 WO PCT/HU1990/000009 patent/WO1990009158A1/en not_active Application Discontinuation
- 1990-01-23 AU AU49415/90A patent/AU4941590A/en not_active Abandoned
- 1990-01-23 BR BR909007098A patent/BR9007098A/en unknown
- 1990-01-23 EP EP90901868A patent/EP0462110A1/en not_active Withdrawn
- 1990-01-23 KR KR1019900702017A patent/KR910700032A/en not_active Application Discontinuation
- 1990-01-23 DE DE19904090201 patent/DE4090201T/de not_active Withdrawn
- 1990-02-07 PL PL28366890A patent/PL162833B1/en unknown
-
1991
- 1991-08-05 FI FI913721A patent/FI913721A0/en not_active Application Discontinuation
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112999433A (en) * | 2021-02-23 | 2021-06-22 | 吴江永元生物科技有限公司 | Cu-Zn composite material intrauterine device and preparation method thereof |
CN112999433B (en) * | 2021-02-23 | 2022-07-05 | 吴江永元生物科技有限公司 | Cu-Zn composite material intrauterine device and preparation method thereof |
Also Published As
Publication number | Publication date |
---|---|
DD291243A5 (en) | 1991-06-27 |
KR910700032A (en) | 1991-09-12 |
DE4090201T (en) | 1992-03-12 |
HU200905B (en) | 1990-09-28 |
RO107542B1 (en) | 1993-12-30 |
BR9007098A (en) | 1991-11-05 |
CN1018521B (en) | 1992-10-07 |
FI913721A0 (en) | 1991-08-05 |
CS30890A2 (en) | 1991-06-11 |
PL162833B1 (en) | 1994-01-31 |
EP0462110A1 (en) | 1991-12-27 |
WO1990009158A1 (en) | 1990-08-23 |
AU4941590A (en) | 1990-09-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN1044758A (en) | Intrauterine contraceptive device | |
US3563235A (en) | Intrauterine contraceptive method | |
CN101702923B (en) | Magnesium-based alloy | |
EP2079413B1 (en) | Intrauterine contraceptive device | |
CN108721707B (en) | Degradable lead and preparation method thereof | |
US20150101613A1 (en) | Intrauterine device with controlled copper ion elution | |
SI8310259A8 (en) | Process for the manufacture of a copper wire for an interuterine birth control device | |
WO2009142780A1 (en) | Implantable medical devices composed of a radiopaque alloy and method making the alloy | |
CN1919161A (en) | Reparable fallopian tube contraception equipment | |
CN114686726B (en) | Degradable Zn-X biomedical material and processing technology thereof | |
Batar | State-of-the-art of intrauterine contraception | |
Sikov et al. | Studies of duplex (Copper-coated) wires for use in intrauterine devices | |
USRE28399E (en) | Intrauterine contraceptive method | |
Edelman et al. | Duration of use of copper releasing IUDs and the incidence of copper wire breakage | |
Zipper et al. | Studies of the physiological activity of IUDs containing copper | |
Apelo et al. | A 3-year evaluation of the TCu380Ag and the Cu-7 | |
Zipper et al. | An overview of IUD research and implications for the future | |
Gal‐Or et al. | Corrosion of a new copper gold or copper platinum intrauterine device | |
Gonen et al. | A copper-based intrauterine device with gold or platinum core: in vitro and in vivo studies | |
Sadovsky et al. | Report on the use of the New Anderson-Ansell “Latex Leaf” IUD containing copper and zinc | |
HU225878B1 (en) | Intra-uterine contraceptive | |
Trimmer | When your patients ask about contraception for the middle years | |
HU212696B (en) | Intrauterine spermicide | |
Ibekwe | Allaying the fears in the use of intrauterine devices |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C13 | Decision | ||
GR02 | Examined patent application | ||
AD01 | Patent right deemed abandoned | ||
C20 | Patent right or utility model deemed to be abandoned or is abandoned |