CN104435959A - Traditional Chinese medicine composition for treating myopia and preparation method of traditional Chinese medicine composition - Google Patents

Traditional Chinese medicine composition for treating myopia and preparation method of traditional Chinese medicine composition Download PDF

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Publication number
CN104435959A
CN104435959A CN201410670993.3A CN201410670993A CN104435959A CN 104435959 A CN104435959 A CN 104435959A CN 201410670993 A CN201410670993 A CN 201410670993A CN 104435959 A CN104435959 A CN 104435959A
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chinese medicine
medicine composition
traditional chinese
magnetitum
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郭亚萍
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/26Iron; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/69Polygalaceae (Milkwort family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9062Alpinia, e.g. red ginger or galangal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a traditional Chinese medicine composition for treating myopia. The composition is prepared from the following medicinal raw materials in parts by weight: 10-30 parts of mulberry leaves, 10-25 parts of feather cockscomb seed, 10-15 parts of polygala tenuifolia, 5-15 parts of alpinia oxyphylla, 5-25 parts of safflower carthamus, 10-30 parts of platycodon grandiflorum, 20-35 parts of cynomorium songaricum and 10-30 parts of magnet. The invention further provides a preparation method of the traditional Chinese medicine composition for treating myopia. The composition can be used for effectively treating the problem of myopia, has a cure rate of 96 percent, has the advantages of scientific formula and no rebound effect, and can be used for improving the content of effective ingredients in products. Clinical application proves that the traditional Chinese medicine composition has a remarkable curative effect, and can be used for remarkably treating the problem of myopia.

Description

One treats bathomorphic Chinese medicine composition and preparation method thereof
Technical field
The present invention relates to field of traditional Chinese medicine technology, be specifically related to one and treat bathomorphic Chinese medicine composition and preparation method thereof.
Background technology
For myopia, although its cause is related to a lot of aspect, mainly internal organs imbalance of YIN and YANG and QI and blood dysfunction.Should show in conjunction with the disease of whole body and eye, determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs.The TCM Ophthalmology expert such as had, uses the rule that treats of differentiation of symptoms and signs for classification of syndrome, myopia is divided and makes following four types: (1) deficiency of the liver and kindey type: should liver and kidney tonifying; (2) the empty type of spleen kidney two: should strengthening spleen, tonifying kidney; (3) insufficiency of heart-QI weak type: should heart tonifying and tranquilizing; (4) liver qi stagnation type.
The method of current treatment myopia is it is preferred that laser therapy, but laser therapy side effect is very large, and very large to human injury, and easily rebounds.
Summary of the invention
Goal of the invention: the first object of the present invention is to overcome the deficiencies in the prior art, provide a kind of safety, toxic and side effects little, do not have rebound can treat bathomorphic Chinese medicine composition.The second object of the present invention is to provide a kind of above-mentioned preparation method being used for the treatment of bathomorphic Chinese medicine composition.
Technical scheme: in order to solve the problems of the technologies described above, the technical solution adopted in the present invention is: one treats bathomorphic Chinese medicine composition, comprises the crude drug of following parts by weight: Folium Mori 10-30 part, Semen Celosiae 10-25 part, Radix Polygalae 10-15 part, Fructus Alpiniae Oxyphyllae 5-15 part, Flos Carthami 5-25 part, Radix Platycodonis 10-30 part, Herba Cynomorii 20-35 part, Magnetitum 10-30 part.
Preferably, the crude drug of following parts by weight is comprised: Folium Mori 20-30 part, Semen Celosiae 15-25 part, Radix Polygalae 13-15 part, Fructus Alpiniae Oxyphyllae 10-15 part, Flos Carthami 15-25 part, Radix Platycodonis 20-30 part, Herba Cynomorii 30-35 part, Magnetitum 20-30 part.
Above-mentioned a kind of preparation method for the treatment of bathomorphic Chinese medicine composition, the method comprises the steps:
(1) according to following parts by weight weighting raw materials: Folium Mori 10-30 part, Semen Celosiae 10-25 part, Radix Polygalae 10-15 part, Fructus Alpiniae Oxyphyllae 5-15 part, Flos Carthami 5-25 part, Radix Platycodonis 10-30 part, Herba Cynomorii 20-35 part, Magnetitum 10-30 part; For subsequent use;
(2) add the soak by water 3 hours of ten times after first getting Folium Mori processed, Semen Celosiae, Radix Polygalae, Fructus Alpiniae Oxyphyllae mixing, filter, leave and take medicinal liquid, medicinal residues are stand-by; To add the soak by water 1 hour of octuple after Flos Carthami, Radix Platycodonis, Herba Cynomorii, Magnetitum mixing again, filter, leave and take medicinal liquid, medicinal residues are stand-by; Medicinal residues in above-mentioned mix, and add the water of five times of its gross weight, decoct 1 hour, filter, leave and take medicinal liquid, are mixed by medicinal liquid, obtain the bathomorphic Chinese medicine composition of described treatment.
Beneficial effect: compared with prior art, advantage of the present invention is: the present invention can effectively treat myopia problem, cure rate is up to 90%, and scientific formulation of the present invention, not easily rebound, effective ingredient amount in product can be improved, prove through Clinical practice, medicine evident in efficacy, can obviously treat bathomorphic problem.
Detailed description of the invention
According to following embodiment, the present invention may be better understood.But those skilled in the art will readily understand, the concrete technology path described by embodiment and result thereof only for illustration of the present invention, and should can not limit the present invention described in detail in claims yet.
Embodiment 1:
One treats bathomorphic Chinese medicine composition, comprises the crude drug of following parts by weight: 10 parts, Folium Mori, Semen Celosiae 10 parts, Radix Polygalae 10 parts, Fructus Alpiniae Oxyphyllae 5 parts, 5 parts, Flos Carthami, Radix Platycodonis 10 parts, Herba Cynomorii 20 parts, Magnetitum 10 parts.
Treat a preparation method for bathomorphic Chinese medicine composition, the method comprises the steps:
(1) according to following parts by weight weighting raw materials: 10 parts, Folium Mori, Semen Celosiae 10 parts, Radix Polygalae 10 parts, Fructus Alpiniae Oxyphyllae 5 parts, 5 parts, Flos Carthami, Radix Platycodonis 10 parts, Herba Cynomorii 20 parts, Magnetitum 10 parts; For subsequent use;
(2) add the soak by water 3 hours of ten times after first getting Folium Mori processed, Semen Celosiae, Radix Polygalae, Fructus Alpiniae Oxyphyllae mixing, filter, leave and take medicinal liquid, medicinal residues are stand-by; To add the soak by water 1 hour of octuple after Flos Carthami, Radix Platycodonis, Herba Cynomorii, Magnetitum mixing again, filter, leave and take medicinal liquid, medicinal residues are stand-by; Medicinal residues in above-mentioned mix, and add the water of five times of its gross weight, decoct 1 hour, filter, leave and take medicinal liquid, are mixed by medicinal liquid, obtain the bathomorphic Chinese medicine composition of described treatment.
Embodiment 2:
One treats bathomorphic Chinese medicine composition, comprises the crude drug of following parts by weight: 30 parts, Folium Mori, Semen Celosiae 25 parts, Radix Polygalae 15 parts, Fructus Alpiniae Oxyphyllae 15 parts, 25 parts, Flos Carthami, Radix Platycodonis 30 parts, Herba Cynomorii 35 parts, Magnetitum 30 parts.
Above-mentioned a kind of preparation method for the treatment of bathomorphic Chinese medicine composition, the method comprises the steps:
(1) according to following parts by weight weighting raw materials: 30 parts, Folium Mori, Semen Celosiae 25 parts, Radix Polygalae 15 parts, Fructus Alpiniae Oxyphyllae 15 parts, 25 parts, Flos Carthami, Radix Platycodonis 30 parts, Herba Cynomorii 35 parts, Magnetitum 30 parts; For subsequent use;
(2) add the soak by water 3 hours of ten times after first getting Folium Mori processed, Semen Celosiae, Radix Polygalae, Fructus Alpiniae Oxyphyllae mixing, filter, leave and take medicinal liquid, medicinal residues are stand-by; To add the soak by water 1 hour of octuple after Flos Carthami, Radix Platycodonis, Herba Cynomorii, Magnetitum mixing again, filter, leave and take medicinal liquid, medicinal residues are stand-by; Medicinal residues in above-mentioned mix, and add the water of five times of its gross weight, decoct 1 hour, filter, leave and take medicinal liquid, are mixed by medicinal liquid, obtain the bathomorphic Chinese medicine composition of described treatment.
Embodiment 3:
One treats bathomorphic Chinese medicine composition, comprises the crude drug of following parts by weight: 20 parts, Folium Mori, Semen Celosiae 15 parts, Radix Polygalae 13 parts, Fructus Alpiniae Oxyphyllae 10 parts, 15 parts, Flos Carthami, Radix Platycodonis 20 parts, Herba Cynomorii 30 parts, Magnetitum 20 parts.
Above-mentioned a kind of preparation method for the treatment of bathomorphic Chinese medicine composition, the method comprises the steps:
(1) according to following parts by weight weighting raw materials: 20 parts, Folium Mori, Semen Celosiae 15 parts, Radix Polygalae 13 parts, Fructus Alpiniae Oxyphyllae 10 parts, 15 parts, Flos Carthami, Radix Platycodonis 20 parts, Herba Cynomorii 30 parts, Magnetitum 20 parts; For subsequent use;
(2) add the soak by water 3 hours of ten times after first getting Folium Mori processed, Semen Celosiae, Radix Polygalae, Fructus Alpiniae Oxyphyllae mixing, filter, leave and take medicinal liquid, medicinal residues are stand-by; To add the soak by water 1 hour of octuple after Flos Carthami, Radix Platycodonis, Herba Cynomorii, Magnetitum mixing again, filter, leave and take medicinal liquid, medicinal residues are stand-by; Medicinal residues in above-mentioned mix, and add the water of five times of its gross weight, decoct 1 hour, filter, leave and take medicinal liquid, are mixed by medicinal liquid, obtain the bathomorphic Chinese medicine composition of described treatment.
Beneficial effect of the present invention is set forth further below by clinical trial.
Select 100 myopias to carry out system clinical observation according to conditions of patients, patient is divided into test group and matched group at random, often organizes 50 people, test group is treated according to the prescription in embodiment 1 or experimental example 2; Matched group takes the bathomorphic Western medicine fluticasone propionate treatment of commercially available current therapies;
Usage and dosage: be decocted in water for oral dose, 2 times on the one.Within 15 days, be a course for the treatment of, totally 3 courses for the treatment of.
The curative effect of test group and matched group clinical trial is as shown in the table:
Group Case load Effective Effectively Invalid Total effective rate %
Test group 50 25 23 5 96%
Matched group 50 2 28 20 60%
Test data statistics in upper table shows, take the patient of this medicine, what have significant curative effect accounts for 50%, and matched group has a significant curative effect accounts for 4%, it can thus be appreciated that test group has the matched group that is far longer than of significant curative effect, has the value of clinical expansion.

Claims (3)

1. the bathomorphic Chinese medicine composition for the treatment of, it is characterized in that, comprise the crude drug of following parts by weight: Folium Mori 10-30 part, Semen Celosiae 10-25 part, Radix Polygalae 10-15 part, Fructus Alpiniae Oxyphyllae 5-15 part, Flos Carthami 5-25 part, Radix Platycodonis 10-30 part, Herba Cynomorii 20-35 part, Magnetitum 10-30 part.
2. one according to claim 1 treats bathomorphic Chinese medicine composition, it is characterized in that, comprise the crude drug of following parts by weight: Folium Mori 20-30 part, Semen Celosiae 15-25 part, Radix Polygalae 13-15 part, Fructus Alpiniae Oxyphyllae 10-15 part, Flos Carthami 15-25 part, Radix Platycodonis 20-30 part, Herba Cynomorii 30-35 part, Magnetitum 20-30 part.
3. a kind of preparation method for the treatment of bathomorphic Chinese medicine composition according to claim 1, it is characterized in that, the method comprises the steps:
(1) according to following parts by weight weighting raw materials: Folium Mori 10-30 part, Semen Celosiae 10-25 part, Radix Polygalae 10-15 part, Fructus Alpiniae Oxyphyllae 5-15 part, Flos Carthami 5-25 part, Radix Platycodonis 10-30 part, Herba Cynomorii 20-35 part, Magnetitum 10-30 part; For subsequent use;
(2) add the soak by water 3 hours of ten times after first getting Folium Mori processed, Semen Celosiae, Radix Polygalae, Fructus Alpiniae Oxyphyllae mixing, filter, leave and take medicinal liquid, medicinal residues are stand-by; To add the soak by water 1 hour of octuple after Flos Carthami, Radix Platycodonis, Herba Cynomorii, Magnetitum mixing again, filter, leave and take medicinal liquid, medicinal residues are stand-by; Medicinal residues in above-mentioned mix, and add the water of five times of its gross weight, decoct 1 hour, filter, leave and take medicinal liquid, are mixed by medicinal liquid, obtain the bathomorphic Chinese medicine composition of described treatment.
CN201410670993.3A 2014-11-21 2014-11-21 Traditional Chinese medicine composition for treating myopia and preparation method of traditional Chinese medicine composition Withdrawn CN104435959A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104740150A (en) * 2015-04-02 2015-07-01 黄文鹏 Fermented ointment helpful for preventing and treating myopia and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104740150A (en) * 2015-04-02 2015-07-01 黄文鹏 Fermented ointment helpful for preventing and treating myopia and preparation method thereof

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Application publication date: 20150325