CN104435243A - Traditional Chinese medicine composition for treating jaundice - Google Patents
Traditional Chinese medicine composition for treating jaundice Download PDFInfo
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- CN104435243A CN104435243A CN201410810420.6A CN201410810420A CN104435243A CN 104435243 A CN104435243 A CN 104435243A CN 201410810420 A CN201410810420 A CN 201410810420A CN 104435243 A CN104435243 A CN 104435243A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/68—Plantaginaceae (Plantain Family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/744—Gardenia
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Abstract
The invention relates to a traditional Chinese medicine composition for treating jaundice. The traditional Chinese medicine composition for treating jaundice is prepared from the following medicinal raw materials: the root of Chinese pulsatilla, ramulus mori, oriental wormwood, cape jasmine, white atractylodes rhizome, plantain herb and cortex dictamni in the mass ratio of (1-3):(1-1.5):(1-3):(1-2):1:(1-2):(1-2). According to the invention, damp heat stasis toxin is used as the main pathogenesis and the starting point of jaundice; the traditional Chinese medicine composition has the effects of detoxifying, removing jaundice, clearing depression and removing dampness; the traditional Chinese medicine composition disclosed by the invention can be used in manners of medicated bath, fuming and washing; the treatment purpose can also be achieved through foot bath and wet packing; the traditional Chinese medicine composition is unnecessary to be taken orally; therefore, burden of liver and kidney is avoided; and the traditional Chinese medicine composition is also widely applied to neonatal jaundice and jaundice patients caused by other various reasons.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine composition being used for the treatment of jaundice.
Background technology
Jaundice a kind ofly raises the sings and symptoms causing skin, mucosa and sclera to turn to be yellow due to serum mesobilirubin, is mostly the dispersivity inflammation of liver parenchymal cell.Clinical signs is that sclera, mucosa, skin and hetero-organization thereof are dyed to yellow.Comparatively general with hepatocellular jaundice and obstructive jaundice in China adult, be common in viral hepatitis, toxic hepatitis, drug-induced liver disease, various liver cirrhosis, former with secondary liver cancer and cholelithiasis etc.Current Western medicine there is no the medicine carrying out effectively treatment for jaundice.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition of effective treatment jaundice.
Technical scheme of the present invention is: a kind of Chinese medicine composition being used for the treatment of jaundice, is prepared from by the crude drug comprising following mass ratio: the Radix Pulsatillae: Ramulus Mori: Herba Artemisiae Scopariae: Fructus Gardeniae: the Rhizoma Atractylodis Macrocephalae: Herba Plantaginis: Cortex Dictamni=(1 ~ 3): (1 ~ 1.5): (1 ~ 3): (1 ~ 2): 1:(1 ~ 2): (1 ~ 2).
The preferred Radix Pulsatillae: Ramulus Mori: Herba Artemisiae Scopariae: Fructus Gardeniae: the Rhizoma Atractylodis Macrocephalae: Herba Plantaginis: Cortex Dictamni=3:1:3:1:1:2:1.5 or 3:1:3:2:1:2:1.
Above-mentioned composition also comprises acceptable adjuvant in pharmacy, and preparation is granule or mixture.Said composition is external.
Said composition is decocted with water by described crude drug, filter and make.Or filtrate is concentrated into paste, add adjuvant and make granule.
The each crude drug effect of the present composition is respectively:
The Radix Pulsatillae: heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery, removing dampness and killing parasites, pharmacological research shows to have antibacterial, antiviral effect;
Ramulus Mori: wind-damp dispelling, the meridian dredging, row aqueous vapor, pharmacological research shows to improve lymhocyte transformation rate, and the Ramulus Mori patient low to lymhocyte transformation rate has certain therapeutical effect;
Herba Artemisiae Scopariae: the effect with clearing away damp-heat, jaundice eliminating subcutaneous ulcer, especially obvious to the effect of infectious jaundice type hepatitis, clinical pharmacology research shows that Herba Artemisiae Scopariae can promote the excretion of bile, alleviate biliary is smouldered, and promotes bilirubinic discharge, protection hepatocyte, promote liver cell regeneration, strengthen the functions of expelling toxin of liver;
Fructus Gardeniae: there is clearing away heat-damp and promoting diuresis, effect that removing pathogenic heat from blood and toxic substance from the body, function of gallbladder promoting protect the liver, Fructus Gardeniae can promote bile secretion, has effect of anti-hyperbilirubinemia;
The Rhizoma Atractylodis Macrocephalae: there is the effect such as invigorating the spleen and benefiting QI, dampness diuretic, modern pharmacological research shows that Rhizoma Atractylodis polysaccharide has the effect improving immunity of organisms and antioxidation, alleviate viral hepatic injury, has benefit during full side is rushed down, eliminating evil and just do not hinder;
Herba Plantaginis: there is clearing away heat and promoting diuresis, effect of removing pathogenic heat from blood and toxic substance from the body, modern pharmacological research confirms, the ursolic acid contained in Herba Plantaginis and cupreol have anti-inflammation and antineoplastic effect;
Cortex Dictamni: heat clearing and damp drying, removing toxic substances of dispeling the wind, has antibacterial, anticancer effect.
The present invention, using hot and humid ecchymosis as the topmost pathogenesis of jaundice and starting point, has removing toxic substances jaundice eliminating, effect of clear strongly fragrant dehumidifying.The lotion of said composition uses Chinese medicinal granule preparation, and its main route of administration is external treatment percutaneous dosing, and skin area is large, and pore is many, apart from outside barrier action, also has the effects such as excretion and Transdermal absorption.Medicine absorbs by transhipments such as mucocutaneous, sweat gland, hair follicle, horny layer, cell and gaps thereof.Administrated method of the present invention can be Traditional Chinese medicine medicated bath, Chinese medicine fumigation and washing, also can reach therapeutic purposes by foot bath and stain of becoming soaked with sweat, without the need to oral, avoid Liver and kidney to bear, now be widely used in neonatal jaundice and the Patients with Jaundice caused by other a variety of causes.
Detailed description of the invention
Embodiment 1
By weight: the Radix Pulsatillae 1 part, Ramulus Mori 1 part, Herba Artemisiae Scopariae 1 part, Fructus Gardeniae 1 part, the Rhizoma Atractylodis Macrocephalae 1 part, Herba Plantaginis 1 part, Cortex Dictamni 1 part.
Embodiment 2
By weight: the Radix Pulsatillae 2 parts, Ramulus Mori 1 part, Herba Artemisiae Scopariae 2 parts, Fructus Gardeniae 1 part, the Rhizoma Atractylodis Macrocephalae 1 part, Herba Plantaginis 1 part, Cortex Dictamni 1 part.
Embodiment 3
By weight: the Radix Pulsatillae 3 parts, Ramulus Mori 1 part, Herba Artemisiae Scopariae 3 parts, Fructus Gardeniae 2 parts, the Rhizoma Atractylodis Macrocephalae 1 part, Herba Plantaginis 2 parts, Cortex Dictamni 2 parts.
Embodiment 4
By weight: the Radix Pulsatillae 3 parts, Ramulus Mori 1.5 parts, Herba Artemisiae Scopariae 3 parts, Fructus Gardeniae 2 parts, the Rhizoma Atractylodis Macrocephalae 1 part, Herba Plantaginis 2 parts, Cortex Dictamni 2 parts.
Embodiment 5
By weight: the Radix Pulsatillae 3 parts, Ramulus Mori 1 part, Herba Artemisiae Scopariae 3 parts, Fructus Gardeniae 1 part, the Rhizoma Atractylodis Macrocephalae 1 part, Herba Plantaginis 2 parts, Cortex Dictamni 1.5 parts.
Embodiment 6
By weight: the Radix Pulsatillae 3 parts, Ramulus Mori 1 part, Herba Artemisiae Scopariae 3 parts, Fructus Gardeniae 2 parts, the Rhizoma Atractylodis Macrocephalae 1 part, Herba Plantaginis 2 parts, Cortex Dictamni 1 part.
Said medicine can be made granule or mixture.Concrete preparation method, for said medicine to be decocted with water, is filtered, is made mixture.Filtrate can be concentrated into paste, add dextrin, granule made by sucrose.Administrated method of the present invention is: dipping; Or Chinese medicine fumigation and washing; Or foot bath; Or stain of becoming soaked with sweat.
Clinical case:
Certain patient, women, 65 years old, on May 13rd, 2012 because of carcinoma of gallbladder recurrence in postoperative 6 months, Intrahepatic metastasis occurred that jaundice was examined over 7 days, see when being admitted to hospital that yellowish body, yellow sclera are obvious; yellow urine brown, liver function test: total bilirubin 104.1 μm of ol/L, bilirubin direct 78.4 μm of ol/L; glutamate pyruvate transaminase 519U/L, GOT2 92U/L.Western medicine diagnose is carcinoma of gallbladder late period, hepatic metastases, liver failure.Infused, Supporting Therapy of suiting the medicine to the illness, by embodiment 5, every part is 10g, decocting 1500ml medicinal liquid, and whole skin is cleaned, every day 1 time.Liver function is checked, total bilirubin 44.7 μm of ol/L, bilirubin direct 28.9 μm of ol/L, glutamate pyruvate transaminase 209U/L, glutamic oxaloacetic transaminase, GOT 97U/L after 7 days.Icteric index declines, and Hepatic function improvement is obvious.
Observe neonate 120 example of obstetrics' birth, all at second day of birth, conventional application is according to embodiment 6 weight ratio, and the Compatible Granule made, specification 29 grams/bag, warm water 3000ml, is dissolved into medicinal liquid, bathing whole body, every day 1 time, each 10 minutes.Controlled observation does not use the neonate of this Chinese medicine, compares 3 days, and after finding this lotion of application, Transcutaneous bilirubin, meconium turn the yellow time than the neonate not having to use rapidly, prove that said preparation can reduce neonatal jaundice.
Claims (7)
1. being used for the treatment of a Chinese medicine composition for jaundice, it is characterized in that the crude drug by comprising following mass ratio is prepared from: the Radix Pulsatillae: Ramulus Mori: Herba Artemisiae Scopariae: Fructus Gardeniae: the Rhizoma Atractylodis Macrocephalae: Herba Plantaginis: Cortex Dictamni=(1 ~ 3): (1 ~ 1.5): (1 ~ 3): (1 ~ 2): 1:(1 ~ 2): (1 ~ 2).
2. the Chinese medicine composition being used for the treatment of jaundice according to claim 1, is characterized in that the Radix Pulsatillae: Ramulus Mori: Herba Artemisiae Scopariae: Fructus Gardeniae: the Rhizoma Atractylodis Macrocephalae: Herba Plantaginis: Cortex Dictamni=3:1:3:1:1:2:1.5 or 3:1:3:2:1:2:1.
3. the Chinese medicine composition being used for the treatment of jaundice according to claim 1 and 2, characterized by further comprising acceptable adjuvant in pharmacy.
4. the Chinese medicine composition being used for the treatment of jaundice according to claim 3, is characterized in that preparation is granule or mixture.
5. the Chinese medicine composition being used for the treatment of jaundice according to claim 1 and 2, is characterized in that said composition is external.
6. the Chinese medicine composition being used for the treatment of jaundice according to claim 1 and 2, is characterized in that said composition is decocted with water by described crude drug, filters and make.
7. the Chinese medicine composition being used for the treatment of jaundice according to claim 6, is characterized in that filtrate to be concentrated into paste, adds adjuvant and make granule.
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| CN201410810420.6A CN104435243B (en) | 2014-12-24 | 2014-12-24 | A kind of Chinese medicine composition being used for the treatment of jaundice |
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| CN201410810420.6A CN104435243B (en) | 2014-12-24 | 2014-12-24 | A kind of Chinese medicine composition being used for the treatment of jaundice |
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| CN104435243B CN104435243B (en) | 2015-12-09 |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105287955A (en) * | 2015-11-09 | 2016-02-03 | 张健 | Traditional Chinese medicine preparation used for treating jaundice and preparation method |
| CN105749060A (en) * | 2016-03-30 | 2016-07-13 | 郑州市中医院 | Traditional Chinese medicine composition for treating fetal jaundice |
| CN105944032A (en) * | 2016-06-27 | 2016-09-21 | 上海长海医院 | Traditional Chinese medicine composition for treating intrahepatic cholestatic jaundice diseases and application thereof |
| CN106344730A (en) * | 2016-08-30 | 2017-01-25 | 济南市儿童医院 | Traditional Chinese medicine composition for treating neonatal jaundice and preparation method thereof |
| CN110538237A (en) * | 2019-09-10 | 2019-12-06 | 杨环宇 | Chinese herbal medicine bath and preparation method thereof |
| CN114130058A (en) * | 2021-11-19 | 2022-03-04 | 云南鸿翔圣琪儿科技有限公司 | Traditional Chinese medicine composition for treating jaundice, preparation method and preparation equipment thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102048869A (en) * | 2009-10-28 | 2011-05-11 | 王宝凤 | TCM prescription for treating jaundice of newborn |
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2014
- 2014-12-24 CN CN201410810420.6A patent/CN104435243B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102048869A (en) * | 2009-10-28 | 2011-05-11 | 王宝凤 | TCM prescription for treating jaundice of newborn |
Non-Patent Citations (1)
| Title |
|---|
| 银羽: "茵陈汤治疗新生儿黄疸疗效观察", 《邯郸医学高等专科学校学报》 * |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105287955A (en) * | 2015-11-09 | 2016-02-03 | 张健 | Traditional Chinese medicine preparation used for treating jaundice and preparation method |
| CN105749060A (en) * | 2016-03-30 | 2016-07-13 | 郑州市中医院 | Traditional Chinese medicine composition for treating fetal jaundice |
| CN105944032A (en) * | 2016-06-27 | 2016-09-21 | 上海长海医院 | Traditional Chinese medicine composition for treating intrahepatic cholestatic jaundice diseases and application thereof |
| CN105944032B (en) * | 2016-06-27 | 2020-09-08 | 上海长海医院 | Traditional Chinese medicine composition for treating intrahepatic cholestatic jaundice diseases and application thereof |
| CN106344730A (en) * | 2016-08-30 | 2017-01-25 | 济南市儿童医院 | Traditional Chinese medicine composition for treating neonatal jaundice and preparation method thereof |
| CN110538237A (en) * | 2019-09-10 | 2019-12-06 | 杨环宇 | Chinese herbal medicine bath and preparation method thereof |
| CN114130058A (en) * | 2021-11-19 | 2022-03-04 | 云南鸿翔圣琪儿科技有限公司 | Traditional Chinese medicine composition for treating jaundice, preparation method and preparation equipment thereof |
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| CN104435243B (en) | 2015-12-09 |
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