CN104431170A - Marine bioactive polysaccharide or oligosaccharide granular tea drink for improving metabolic syndrome (six highs and one lipid) - Google Patents
Marine bioactive polysaccharide or oligosaccharide granular tea drink for improving metabolic syndrome (six highs and one lipid) Download PDFInfo
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Abstract
The invention provides a marine bioactive polysaccharide or oligosaccharide granular tea drink for improving metabolic syndrome (six highs and one lipid, namely high blood pressure, high blood lipid, high blood sugar, high uricemia, high insulinemia, high body weight and high fatty liver). The marine bioactive polysaccharide or oligosaccharide granular tea drink is prepared by using as a dominant raw material, and blending 0.5-3.0 parts of marine bioactive polysaccharide or oligosaccharide with 0.5-4.0 parts of algae powder, 0.5-1.5 parts of cordyceps militaris, 0.05-0.5 part of bamboo leaves, 0.5-1.5 parts of burdock and 0.5-2.0 parts of corn stigma in parts by weight, wherein the components are uniformly mixed to keep powdery, or granulated and pelleted into the granular tea drink or into tea bags which are brewed or soaked in boiled water for use.
Description
Technical field
The invention belongs to tea-drinking field, be specifically related to marine bioactivity polysaccharide or oligosaccharides particle tea-drinking that one improves metabolic syndrome " a six high fat ".
Background technology
Metabolic syndrome is also often colloquially referred to as " a six high fat ", i.e. hypertension, high fat of blood, hyperglycaemia, hyperuricemia, hyperinsulinemia, high body weight and higher fatty acid liver.This " six high fat " in fact all belongs to endocrine system disease.They are associated with each other, juxtaposition, reciprocal causation, cause vicious circle.Intervene this " seven sword " be suspended on the middle aged number of people if do not attract great attention early and will bring the serious consequences such as diabetes, coronary heart disease, headstroke, gout, cirrhosis, thus patients ' life quality is declined, life expectancy shortens, and case fatality rate raises.
In the U.S. more than 17 years old adult, the metabolic syndrome incidence of disease is 42%, accounts for the whole America population 1/3.China has 1/8 people to suffer from metabolic syndrome in being approximately grown up, and within more than 60 years old, prevalence reaches 30%.
In various crowd, obesity, hypertension, high fat of blood, artery sclerosis, diabetes, gout, fatty liver etc., often to some extent superposition be present in it same person, they are associated with each other, juxtaposition, reciprocal causation, cause vicious circle.This is undisputable fact.
According to data: investigate the relation between dyslipidemia, hyperuricemia, diabetes, hypertension and obesity and FPI exception from 15800 general populations, find there is obvious dependency relation between these factors, its degree of correlation is followed successively by high triglyceride (triglyceride) and low hdl, high triglyceride (triglyceride) and diabetes, hyperuricemia and hypertension, hypertension and low hdl, diabetes and hyperuricemia.These superimposed factors, accelerate the quick aggravation of atherosclerotic, cardiovascular and cerebrovascular disease.
According to the investigation of Japanese health ministry, hypertension, hyperglycaemia, high fat of blood, hyperuricemia, fat five hazards, not possess the people of above-mentioned five hazards completely, when heart disease rate is 1, then have hazards, its heart disease rate increases by 5.1 times, has 2 hazards, and its heart disease rate increases by 15.8 times, have 3-4 hazards, its cardiopathic incidence of disease is up to 35.8 times, and gather around by 5 hazards, its heart disease rate is up to 120 times.Metabolic syndrome is the most fearful, even each hazards are mild state, as long as there is more than 1 factor to exist simultaneously, will cause major diseases such as suffering from life-threatening heart disease, headstroke, gouty nephropathy.
The diversity of marine bioactivity polysaccharide or oligosaccharides and effect popularity, for comprehensively improving human endocrine disease, have positive meaning.Be not only simple reduction blood fat, steadily blood sugar.To adjustment blood pressure, improve Uric Acid excretion, suppress uric acid to generate, promote to lose weight, all have good effect.Regulating action multi-faceted so just, has for improving metabolic syndrome (" six high fat) advantage that other animals and plants products are larger.And marine polysaccharide or oligosaccharides have proved to have various physiological regulation function, some is for improving the comprehensive physique of body, comprehensive human body can be regulated, multi-facetedly improve hypertension, high fat of blood, hyperglycaemia, hyperuricemia, hyperinsulinemia, high body weight and height, fatty liver, have good preventive and therapeutic effect to metabolic syndrome.
Marine resources are immeasurable huge precious deposits, sp act composition contained in marine organisms, for capturing of some difficult and complicated cases provides more possibility.Marine organisms are in the so special enclosed environment of seawater for a long time, create the metabolic system different from terrestrial life and body defending system during evolution, therefore contain many functions in marine organisms.The physiological activator that some are special, structure is special, in high salt, high pressure, anoxic, unglazed special ecological environment, marine bioactivity polysaccharide or oligosaccharides will carry important physiological function, are the important active materials of a class.Marine polysaccharide or oligosaccharides have proved to have various physiological regulation function, and some has important function for improving the comprehensive physique of body.Therefore utilizing marine bioactivity polysaccharide or oligosaccharides scientifically and rationally, to improving body condition, there is positive effect.
" integration of drinking and medicinal herbs, take good care of with tea " is the method for preventing and curing diseases that Ancient Times in China passes on tool distinct Chinese characteristics.Therefore take tea-drinking method, be not only the succession of " integration of drinking and medicinal herbs ", and in the mode that tea is taken good care of, it meets the feature of metabolic syndrome crowd physiological metabolism circulation, is improve the approach that metabolic syndrome " a six high fat " is a science practicality.
At present, the product that raw material taken as the leading factor by food source property marine bioactivity polysaccharide or oligosaccharides belongs to the stage at the early-stage, only has with land animals and plants for the medicinal tea of formula or based on the special dietary seafood of marine organisms activity polysaccharide through inquiry in patent document and non-patent literature.Not yet find that effectively " " plant specializes in the record of metabolic syndrome particle tea-drinking drunk by people to integration of drinking and medicinal herbs in tea-drinking mode for primary raw material preparation land with marine bioactivity polysaccharide or oligosaccharides.
Summary of the invention
The object of the invention is for Metabolic Syndrome Patients physilogical characteristics, take good care of requirement, provide a kind of improve Metabolic Syndrome Patients special containing food source property marine bioactivity polysaccharide or oligosaccharides tea-drinking, have and improve body nutrition condition, realize regulating health acid-base balance, help body, conditioning engine body metabolic function, voltage stabilizing, stabilizing blood sugar level, lipopenicillinase, deacidification, dissolving gout calculus, entirety to improve the effects such as life quality.
For reaching above-mentioned purpose, the marine bioactivity polysaccharide of one provided by the invention is improved " a six high fat " metabolic syndrome or oligosaccharides particle tea-drinking, be take raw material as the leading factor with marine bioactivity polysaccharide or oligosaccharides, be equipped with seawood meal, Cordyceps militaris, the leaf of bamboo, burdock, corn stigma be mixed with and form.
The weight of marine bioactivity polysaccharide or oligosaccharides granular tea kitchenware body that the present invention improves metabolic syndrome " a six high fat " is:
Material component comprises: marine bioactivity polysaccharide or oligosaccharides, seawood meal, Cordyceps militaris, burdock, the leaf of bamboo, corn stigma, and each component is prepared by weight ratio: marine bioactivity polysaccharide or oligosaccharides 0.5 ~ 3.0, seawood meal 0.5 ~ 4.0, Cordyceps militaris 0.5 ~ 1.5, burdock 0.5 ~ 1.5, the leaf of bamboo 0.05 ~ 0.5, corn stigma 0.5 ~ 2.0; Described marine bioactivity polysaccharide or oligosaccharides, comprise marine bioactivity polysaccharide or marine bioactivity oligosaccharides.
Further improvement is, described marine bioactivity polysaccharide or oligosaccharides are any one in algal polysaccharides, alga oligosaccharides, ocean shell class polysaccharide, ocean shell class oligosaccharides, marine animal and microbial polysaccharide and marine animal and microbial oligosaccharide, several or whole;
Described algal polysaccharides or oligosaccharides are any one in algal polysaccharides, alga oligosaccharides, sodium alginate, fucoidin and agar, several or whole;
Described ocean shell class polysaccharide or oligosaccharides, in chitosan, chitin oligo saccharide, sea urchin shell polysaccharide, pearl powder, nacreous layer powder, shitosan, chitosan oligosaccharide and ammonia sugar any one, several or whole;
Described marine animal and microbial polysaccharide or oligosaccharides are any one in marine microalgae polysaccharide or oligosaccharides, glycosaminoglycan, sea cucumber polysaccharide, several or whole;
Further improvement is, selects powdery alga oligosaccharides, chitosan oligosaccharide, kelp powder, Cordyceps militaris, the leaf of bamboo, burdock, corn stigma, presses row weight proportion and be prepared:
(1) marine bioactivity polysaccharide or oligosaccharides: alga oligosaccharides 0.3g, chitosan oligosaccharide 0.2g;
(2) seawood meal: kelp powder 0.5g;
(3) Cordyceps militaris: 0.5g;
(4) leaf of bamboo: 0.05g;
(5) burdock: 0.5g;
(6) corn stigma: 0.5g.
Further improvement is, selects powdery alga oligosaccharides, ammonia sugar, kelp powder, Cordyceps militaris, the leaf of bamboo, burdock, corn stigma, presses row weight proportion and be prepared:
(1) marine bioactivity polysaccharide or oligosaccharides: alga oligosaccharides 0.5g, ammonia sugar 0.5g;
(2) seawood meal: kelp powder 0.3g;
(3) Cordyceps militaris: 0.65g;
(4) leaf of bamboo: 0.05g;
(5) burdock: 1g;
(6) corn stigma: 1g.
Further improvement is, selects powdery chitosan, agar, kelp powder, Cordyceps militaris, the leaf of bamboo, burdock, corn stigma, presses row weight proportion and be prepared:
(1) marine bioactivity polysaccharide or oligosaccharides: chitosan 1g, agar 1g;
(2) seawood meal: kelp powder 0.3g;
(3) Cordyceps militaris: 0.65g;
(4) leaf of bamboo: 0.05g;
(5) burdock: 0.5g;
(6) corn stigma: 0.5g.
Further improvement is, selects powdery chitosan oligosaccharide, kelp powder, Cordyceps militaris, the leaf of bamboo, burdock, corn stigma, presses row weight proportion and be prepared:
(1) marine bioactivity polysaccharide or oligosaccharides: chitosan oligosaccharide 1g;
(2) seawood meal: kelp powder 0.3g;
(3) Cordyceps militaris: 0.65g;
(4) leaf of bamboo: 0.05g;
(5) burdock: 1g;
(6) corn stigma: 1g.
Further improvement is, selects powdery alga oligosaccharides, kelp powder, Cordyceps militaris, the leaf of bamboo, burdock, corn stigma, presses row weight proportion and be prepared:
(1) marine bioactivity polysaccharide or oligosaccharides: alga oligosaccharides 1g;
(2) seawood meal: kelp powder 0.3g;
(3) Cordyceps militaris: 0.65g;
(4) leaf of bamboo: 0.05g;
(5) burdock: 1g;
(6) corn stigma: 1g.
Further improvement is, selects powdery algal polysaccharides, kelp powder, Cordyceps militaris, the leaf of bamboo, burdock, corn stigma, presses row weight proportion and be prepared:
(1) marine bioactivity polysaccharide or oligosaccharides: algal polysaccharides 3g;
(2) seawood meal: kelp powder 4g;
(3) Cordyceps militaris: 1.5g;
(4) leaf of bamboo: 0.5g;
(5) burdock: 1.5g;
(6) corn stigma: 2.0g.
Further improvement is, each material component mix keep its powdery or through granulation, press grain, make graininess or make tea in bag, with boiling water Instant Drinks or bubble drink.
Marine bioactivity polysaccharide:
There is many natural activity polysaccharide in marine organisms, can three major types be divided into, marine bioactivity polysaccharide, ocean shell class polysaccharide and marine animal and microbial polysaccharide according to its source difference.Marine polysaccharide aboundresources, they often have special chemical constitution, and with the active group of uniqueness, such as chitin is with amino etc., thus make marine polysaccharide show certain physiologically active.
Marine bioactivity oligosaccharides:
Marine bioactivity oligosaccharides obtains from marine animal, algae and microbial polysaccharide mainly through method degradeds such as chemistry and biological enzymes.Oligosaccharides, also known as compound sugar, is the glycan molecule that two or more monosaccharide units are connected to form.
Due to the structure that marine active polysaccharide molecular weight is larger and special, cause the solubility of polysaccharide lower, solution viscosity is comparatively large, restriction polysaccharide function and application.
Take marine polysaccharide as raw material, the oligosaccharides prepared by degradation pathway not only dissolubility is better, and shows the stronger physiologically active of relative polysaccharide.People have done a lot of research in marine organisms oligosaccharides application aspect, and the algal polysaccharides that the algin such as contained from kelp extracts prepares brown alga oligose after degraded, and its effect is extensive, acts on stronger.The effect such as propagation beneficial bacteria of intestinal tract, external application moisturizing whitening, antitumor, Immune-enhancing effect, antibacterial anti-inflammatory, adjustment human acid-base balance can be played.Alginate in addition in such as bulk kelp, rock algae is according to polysaccharide and have antitumor action and cytotoxicity, also may have certain reaction to humoral immunity.Can allevating angina pectoris.Reduction cholesterol, hypertension improve arteriosclerosis; Tracheitis; Asthma etc.
Marine bioactivity polysaccharide of the present invention or oligosaccharides are one in algal polysaccharides or oligosaccharides, ocean shell class polysaccharide or oligosaccharides and marine animal and microbial polysaccharide or oligosaccharides, several or whole.
Described algal polysaccharides or oligosaccharides are one in algal polysaccharides, alga oligosaccharides, sodium alginate, fucoidin, agar, several or whole.
Described ocean shell class polysaccharide or oligosaccharides are one in chitosan, chitin oligo saccharide, sea urchin shell polysaccharide, pearl powder, nacreous layer powder, shitosan, chitosan oligosaccharide and ammonia sugar, several or whole.
Described marine animal and microbial polysaccharide or oligosaccharides are one in marine microalgae polysaccharide or oligosaccharides, glycosaminoglycan, sea cucumber polysaccharide, several or whole.
Described algal polysaccharides or oligosaccharides are one in algal polysaccharides, alga oligosaccharides, sodium alginate, fucoidin, agar, several or whole.
Algal polysaccharides or oligosaccharides: algal polysaccharides is mainly from marine algas such as sea-tangle, deer's tail dish (sargassum fusifome), bulk kelp, yellow tang, bladder-wracks.Algal polysaccharides mainly comprises algin, fucoidin and laminaran.The algin, fucoidin and the laminaran that obtain is separated from sea-tangle.The purified sodium alginate obtained.
Algal polysaccharides is a kind of edible and don't by the macromolecular polysaccharide of human consumption, and it has the effects such as water imbibition, adsorptivity, cationic exchange and gel filtration in stomach and intestine.Have following functions: hypoglycemic, hypotensive, reducing blood lipid, reduce cholesterol, prevention fatty liver, repairs kidney injury, reduces uric acid, gets rid of uric acid crystal in body; Hinder the absorption of radioactive element, contribute to getting rid of heavy metal of body; Increase satiety, health slimming; Accelerate enterogastric peristalsis, Constipation.
The alga oligosaccharides prepared by algal polysaccharides by biodegradationpathway system not only dissolubility is better, and shows the stronger physiologically active of relative polysaccharide.Alga oligosaccharides such as through Small molecular has stronger biologically active, has obvious health-care effect: the effects such as the adjustable and preventing hypertension of brown alga oligose, retarding cardiovascular be old and feeble, improve microcirculation, regulate human acid-base balance, have more hypoglycemic, reducing blood lipid, immunity moderation; Micromolecular sodium alginate can reducing blood lipid; Small molecular calcium alginate is the novel calcium source of supplementary calcium food, is easy to absorb; Small molecular alginic acid zinc can brain tonic and intelligence development and prevention dementia of middle-and old aged man; Small molecular ferric alginate can be mended iron, enrich blood; Low molecule alginic acid magnesium can Prevention and Curation coronary heart disease.Potassium alginate oligosaccharides can purify the blood, maintenance blood vessel.By regulating the rising of free calcium ion concentration in VSMC slurry, thus the synthesis reducing its DNA and protein suppresses the propagation of VSMC, suppresses thickening of vascular wall.This treatment for various cardiovascular and cerebrovascular disease and prevention have great meaning and fundamentally can prevent the generation of various cardiovascular and cerebrovascular disease.
Fucoidin: fucoidin is also known as fucoidin, algal polysaccharide sulfate, it is specific marine active polysaccharide in brown algae sea-plant (sea-tangle etc.), rare sulfuric ester ionic natural polysaccharide is belonged at occurring in nature, prove through a large amount of scientific research, there is bidirectional modulation immunity, scavenging free radicals, anti-ageing, anticoagulation and antithrombotic, antitumor viral with HIV, elimination gastronintestinal system is disorderly, antiallergy, strengthen liver function, reduce high fat of blood and hypertension, stabilizing blood sugar level, and there is the regeneration of promotion skin, the physiological function more than more than 20 such as skin moisture-keeping.
Agar: be by agar or river hedge (belonging to red algae) after being heated to dissolve, in addition the marine alga elite of cooled and solidified.Agar contains abundant dietary fiber (content is 80.9%), and protein content is high, and heat is low, and have toxin-expelling and face nourishing, purging intense heat, ease constipation, hypotensive, hypoglycemic and protective effect on cancer risk, food and agricultural organization of united state confirms as 21 century healthy food.Agar can absorb moisture in enteron aisle, and intestinal contents is expanded, and increases stool amount, stimulates intestines wall, helps improve constipation.Certain preventive and therapeutic effect is had to hypertension, high fat of blood.Can clearing lung and eliminating phlegm, clearing heat and expelling damp, nourishing Yin and falling fire, cooling blood and hemostasis.
Sodium alginate: have another name called sodium alginate, seaweed gel, algin, alginates is by the natural polysaccharide carbohydrate extracted in sea-tangle.A kind of safe food additives are not only by sodium alginate, and can be used as the base material of bionic foods or remedy diet, because it is actually a kind of native cellulose, the absorption of fat sugar and cholate can be slowed down, have reduce serum cholesterol, the effect of triglycerides and blood sugar in blood, can the modern disease such as preventing hypertension, diabetes, obesity.It can suppress poisonous metal as the accumulation in vivo such as strontium, cadmium, lead in enteron aisle, exactly because these important function of sodium alginate, is at home and abroad day by day valued by the people.Japanese calls the food being rich in sodium alginate " life prolonging food ".
Described ocean shell class polysaccharide or oligosaccharides are one in chitosan, chitin oligo saccharide, sea urchin shell polysaccharide, pearl powder, nacreous layer powder, shitosan, chitosan oligosaccharide and ammonia sugar, several or whole.
Chitosan: chitosan has reinforced immunological function, have inhibitory action to cancer, suppress aging, reduce cholesterol, hypotensive activity, strengthening liver function, to the regulating action of neural, internal system, improve have a pain in the back, harmful substance be excluded in external in adsorbent.
Chitin oligo saccharide: chitosan is obtained chitin oligo saccharide through special biological enzyme technology process, have water-soluble better, the feature of function is large, biologically active is high small-molecular-weight.Research proves: chitin oligo saccharide has raising immunity, suppress cancerous swelling Growth of Cells, promote that liver spleen antibody is formed, promote the absorption of calcium and mineral matter, profitable strain such as human body such as propagation Bifidobacterium, lactic acid bacteria etc., reducing blood lipid, hypotensive, hypoglycemic, adjustment cholesterol, fat-reducing, the functions such as prevention AD.
Sea urchin shell polysaccharide: there is significantly antibacterial and antioxidation activity.Inhibitory action in various degree is all had to lung adenocarcinoma cell, breast cancer cell and cervical cancer cell.
Pearl powder: pearl powder contains 18 seed amino acids, wherein 7 kinds is the calcium carbonate of essential amino acid, aragonite structure, 20 various trace elements and Cobastab.The Pharmacopoeia of the People's Republic of China and " Chinese medicine voluminous dictionary " all indicate: pearl has arresting convulsion of calming the nerves, the effect such as screen, detoxify and promote granulation is gone in improving eyesight, and modern study also shows that pearl powder is improving body immunity, delays senility, all having unique effect in freckle removing and whitening, supplement calcium etc.Develop immunitypty, supplement calcium, Bao Chunyan decline, improving water flood, treatment ulcer, nourish the liver to improve visual acuity, secondary buck.
Nacreous layer powder: have and calm the nerves, heat-clearing, the effect of removing toxic substances.Can be used for neurasthenia, pharyngitis, control dispute outward and swell and ache.Nacreous layer powder also has flush coat nti-freckle, it is allergic to treat, remove the multi-efficiency such as acne, moisturizing.
Shitosan: shitosan is a kind of natural material, has powerful Anion-adsorption power, is applicable to reduce cholesterol and be free from side effects.Shitosan passes through the suction-operated between the chlorion of self and ammonia radical ion, excretion chlorion.Therefore, shitosan reduces angiotensin II.It contributes to preventing hypertension, particularly the crowd of those Excess free enthalpy salt.A remarkable characteristic of shitosan is adsorption capacity.Many low-molecular-weight materials, such as metal ion, cholesterol, triglycerides, cholic acid and organic mercury etc., can be adsorbed by shitosan.Particularly shitosan not only can adsorb magnesium, potassium, and can adsorb zinc, calcium, mercury and uranium.The adsorption activity of shitosan can play a role selectively.These metal ions concentration in human body is too high is harmful.Shitosan has the series of biologic effect of activating machine system, mediation airframe systems, improves cytophagous systemic-function.Macrophage Surface also exists the acceptor of bacterial polysaccharides, and shitosan is as the analog of bacterial polysaccharides, can activate by stimulating expression of macrophage, produce following reaction: promote its phagocytic function, strengthen its cooperative effect in other immune response, thus realize the adjustment of body to T cell, NK cell and B cell, the cellullar immunologic response of mediation body and HI.Therefore, shitosan has the immunoregulation effect to body.
Chitosan oligosaccharide: chitosan oligosaccharide is also Chitosan poly oligosaccharide, also claims chitin oligo saccharide, is a kind of brand-new product obtained through special biological enzyme technology process by shitosan, be water-soluble better, function is large, biologically active is high low molecular weight product.It has the unexistent higher solubility of shitosan and easily by the function of many uniquenesses such as organism absorbs, it act as 14 times of shitosan.
Chitosan oligosaccharide has: immunological regulation, regulate health pH value, regulate hormone, reducing blood lipid, hypoglycemic, hypotensive, row's cholesterol, re-scheduling metal ion, toxin expelling element, the transfer of inhibition cancer cell, inhibition cancer cell, suppresses the function of carcinomycin.Chitosan oligosaccharide also has good antibacterial action: prevention or treatment are by bacterial Animal diseases such as staphylococcus aureus, Escherichia coli, Actinobacillus, streptococcus mutanses.Can the disease resistance of inducing plant, immunity and killing action are produced to multiple fungi, bacterium and virus.At anti-oxidation method, chitosan oligosaccharide can eliminate human body oxygen radical, and activation equipment body cell, delays senility, and suppress skin surface harmful bacteria to grow, performance of keeping humidity is excellent.And have promotion union: impel osteoblastic activity to increase, make bone morphogenetic protein (BMP) strengthen at repair of fractured bones early expression, expression time in advance, thus promote repair of fractured bones simultaneously.Improve gut flora: chitosan oligosaccharide promotes growth of probiotics as prebiotics in enteron aisle, the beneficial bacterium such as lactic acid bacteria, Bifidobacterium in body can be made to breed in a large number, suppress the growth of the harmful bacterias such as Escherichia coli, Salmonella, staphylococcus aureus, Tiny ecosystem in body is made to reach natural equilibrium, to improve GI normal physiological function.
Ammonia sugar: marine organisms ammonia sugar obtains mainly through chitin acidolysis, and the full name of ammonia sugar is D-Glucosamine, can be divided into D-Glucosamine Hydrochloride and D-aminoglucose sulfate.Ammonia sugar is the important component part of the extremely strong proteoglycan of hydrophily, and its can collagen in synthesized human, is very easily absorbed by the body.Ammonia sugar is widely used as the nutritious supplementary pharmaceutical of articular cartilage, be American-European medical circle uniquely approve to the medicative nutrient and healthcare products of bone and joint diseases tool.
Described marine animal and microbial polysaccharide or oligosaccharides are the one in marine microalgae polysaccharide or oligosaccharides, glycosaminoglycan, several or whole.
Marine microalgae polysaccharide: be to work in coordination with through ultrasonication through marine chlorella, P latymonas subcordifomis and Isochrysis galbana that distilled water extracts, sephadex column purification obtains a kind of smart polysaccharide respectively.Marine microalgae polysaccharide has antiviral, antitumor, anti-ageing, radioresistance and hypoglycemic isoreactivity effect,
Glycosaminoglycan: isolate various glycosaminoglycan after extracting from the marine animals such as stichopus japonicus, sea cucumber, starfish, shark, cuttlefish, scallop, crustacean pteria martensii, it has the various active such as anticoagulation, antitumor, reducing blood lipid, raising immunity.
Algal polysaccharides of the present invention or oligosaccharides, refer to that from marine alga, extract alginic acid is combined with various mineral matter element, then drying pulverizes the flour be prepared from.
Ocean of the present invention shell class polysaccharide or oligosaccharides, refer to flour pearl or mother pearl shellfish are prepared from by physical method; Chitosan, chitin oligo saccharide and ammonia sugar are by chitin by biochemical technology or biological enzymolysis technology, then drying pulverizes the flour be prepared from.
Marine animal of the present invention and microbial polysaccharide or oligosaccharides, refer to by sea mollusk, shellfish, fish-bone through enzymolysis, filtering albumen and purifying, then the flour prepared through Vacuum Concentration or spraying dry.
Seawood meal: food source property marine algae is rich in algin, sweet mellow wine, vitamin and multi mineral prime element as trace elements such as potassium, iron, calcium, phosphorus, iodine, selenium, cobalts, also containing crude protein 10%-40%, crude fat 0.30%-50%, carbohydrate 30%-60%.Scientific research shows, seawood meal can regulate the metabolic function of human body, develop immunitypty, health care, benefit brain and enhancing intelligence, anti-ageing, can prevent Thyroid Gland Swell, ephrosis, strengthening skin gloss and elasticity, softening blood vessel, reduction cholesterol, is a kind of cosmetic good merchantable brand; All right lipopenicillinase, step-down, prevent obesity, hypertension, cardiovascular disease etc.
Seawood meal of the present invention is one in chlorella powder, Dunaliella peircei powder, ulva lactuca powder, Kelp Powder, skirt dish powder, laver powder, kelp powder, Algemin, pelvetia silquosa powder and Eucheuma powder, several or whole.
Seawood meal of the present invention, refers to and is cleaned by marine alga, except raw meat, filter are assorted, dry, pulverizes and the flour of preparation.
Cordyceps militaris: Cordyceps militaris is Ascomycotina, ergot Zoopagales, the type sepecies of Clavicipitaceae, Cordyceps.Have another name called northern Chinese caterpillar Fungus, northern Cordyceps militaris, Chinese caterpillar fungus etc.Worldwide distribution natural resources quantity is little.The traditional Chinese medical science is thought, Chinese caterpillar fungus enters lung kidney two warp, can tonifying lung cloudy, again can kidney-replenishing, cure mainly and suffer from a deficiency of the kidney, impotence and seminal emission, soreness of waist and knee joint, weak after being ill, chronic cough is weak, and phthisical cough phlegm blood, spontaneous sweating etc. are unique a kind of Chinese medicine that can balance simultaneously, regulate negative and positive.Cordyceps militaris medical value is the most remarkable.Cordycepic acid (sweet mellow wine) can fall low intracranial pressure significantly, promotes body metabolism, thus makes cerebral hemorrhage and cerebral thrombosis disease be eased.Cordycepin is a kind of nucleosides material with antibacterial activity, has very strong inhibitory action to core poly A polymerase.MRNA dysmaturity is made, the growth of inhibition cancer cell in DNA transcript mRNA process.And have hypoglycemic effect.Cordyceps sinensis polysaccharide is a kind of galactomannans of height branch, and it can promote lymphocyte transformation, improves the antibody content of serum IgG and the immunologic function of body, strengthens the anticancer ability pressing down cancer of body self.SOD (superoxide dismutase) can eliminate superoxide radical in body, has anti-ageing, the anticancer effect pressing down cancer.In addition; Cordyceps militaris is also containing abundant selenium (Se); this trace element by acknowledged be the trace element of needed by human; it is the activated centre of glutathione peroxidase; be connected on the peptide chain of zymoprotein with the form of selenocystein; the normal permeability of the stability of Cell protection film, and the generation of immune stimulatory globulin and antibody, strengthen immunity of organism and oxidation resistance.Meanwhile, a large amount of scientific practice proves that selenium can the growth of inhibition cancer cell significantly.
Cordyceps militaris Cordyceps militaris of the present invention is the abbreviation of northern CORDYCEPS, also cry Cordyceps militaris or pupa grass or golden Chinese caterpillar fungus or cordyceps militaris sporocarp etc.
Cordyceps militaris powder of the present invention, refer to Cordyceps militaris is cleaned, filter assorted, dry, pulverize and preparation flour.
The leaf of bamboo: Effective Components from Bamboo Leaves comprises flavones, phenolic ketone, anthraquinone, lactone, polysaccharide, amino acid, trace element etc., has excellent Green Tea Extract, anti-oxidant, anti-ageing, antifatigue, reducing blood lipid, prevention cardiovascular and cerebrovascular disease, protection liver, expansion capillary, dredging microcirculation, activation brain, promotes memory, improving water flood, anticancer, beautifies the effects such as skin.According to research reports, in " the international natural meeting of Second Committee ", domestic and international multidigit scholar reports the impact of bone marrow toxicity and the immunological function repression risen anticancer efficacy-enhancing ingredient about natural biological flavones, on the impact of patients with coronary heart disease microcirculation, platelet function and the hemorrhage improvement of cardiac muscle.The leaf of bamboo is the heat-clearing and detoxifying drug that the traditional Chinese medical science is traditional simply.There is clearing heat and relieving fidgetness, the effect of diuresis of promoting the production of body fluid.Can control pyreticosis polydipsia, children's shies hysteria, coughs against telling nosebleed, flushing, scanty drak urine, aphthous stomatitis tongue boil etc.
The leaf of bamboo of the present invention is ten of grass henon bamboo.Specifically refer to the leaf of bamboo is cleaned, water extraction, concentrated, spraying dry and the flour prepared.
Burdock: the fiber of burdock can promote intestinal peristalsis, helps defecation, reduces body inner cholesterol, and minimizing toxin, refuse accumulate in vivo, reaches prevention of stroke and the effect of preventing and treating cancer of the stomach, the cancer of the uterus.There is chemical reaction in burdock, can produce more than 30 kinds materials in vivo, and wherein " volume folic acid " can prevent human body cell from bad change occurring, and prevents cancer cell from producing.Meanwhile, burdock promotes the propagation of cells in vivo, and strengthening and enhancing white blood cell, " blood platelet ", makes T cell with the speed increment of 3 times, reinforced immunological power, promote anticancer effect.Doctor trained in Western medicine thinks burdock except having diuresis, it is long-pending to disappear, eliminate the phlegm except the pharmacological actions such as stopping leak, also for the dietotherapy of constipation, hypertension, high-cholesterol disease.Research shows, burdock has significantly hypoglycemic, reducing blood lipid, hypotensive, tonifying kidney and strengthening yang, relax bowel and inhibition cancer cell grows, spreads and move the effect of abandoning heavy metal in water, is ideal natural health care.Burdock also may clear up blood rubbish, impels the metabolism of cells in vivo, prevents aging, makes skin beauty careful, can eliminate color spot, dark brown spot.
Burdock another name of the present invention is ox dish, Great Burdock Achene, and dislike real, great burdock achene, bat is stung, Japan radish, Fructus Arctii, pizzle dish.
Burdock of the present invention, refer to burdock raw material cleaned, dry up, cut into slices, secondary dries up, airing or people's bake oven is baked, cooling of coming out of the stove, pulverize and the flour of preparation.
Corn stigma: corn stigma is the zeistic style of grass and column cap.Have another name called maize palpus, corn stigma taste is sweet, light, and property is put down; Return kidney, liver, gallbladder channel; Light weight oozes and falls.There is inducing diuresis to reduce edema, effect of flat liver cholagogic.Cure mainly oedema, dribbling urination, jaundice, cholecystitis, gall stone, high blood pressure, diabetes, alactation.Correlative study shows: corn stigma has effect for the treatment of chronic nephritis.Work and be mainly manifested in diuresis, renal function improves, and edema disappears or alleviates, the aspects such as Urine proteins disappearance or attenuating.In corn stigma, contained Maize silk flavones can remove superoxide anion.Meanwhile, it also has the effect of suppression uric acid, proves that corn stigma has antigout effect.
Corn stigma of the present invention is for being the zeistic style of grass and column cap.Have another name called maize palpus.
Corn stigma of the present invention, refer to corn stigma raw material is cleaned, airing or people's bake oven are baked, pulverize and the flour prepared.
Above-mentioned various raw material mixes, and can keep its powdery, or through granulation, press grain, make powdery or graininess, directly to drink or boiling water brews the particle tea-drinking drunk.
Marine bioactivity polysaccharide or the oligosaccharides particle tea-drinking improving metabolic syndrome " a six high fat " provided by the invention, has no side effect, edible safety.With reference to the achievement in research of marine biology and marine life science, the theory that the achievement in research of modern nutriology and traditional methods to keep in good health kept healthy combines and is equipped with land " integration of drinking and medicinal herbs " plant, takes in tea-drinking mode.Drink for a long time and realize regulating health acid-base balance, help body, conditioning engine body metabolic function, voltage stabilizing, stabilizing blood sugar level, lipopenicillinase, deacidification, dissolving gout calculus, entirety to improve the effects such as life quality.Its characteristic and the following aspects is mainly manifested in the effect of body:
1, overall coordination improves six high fat comprehensively
Marine active polysaccharide in this formula or oligosaccharides and corn stigma, burdock all have regulate blood pressure, blood fat, blood sugar, lose weight, effect that decorporation uric acid, softening blood vessel, reduction cholesterol etc. are many.And cooperatively interact, nurse one's health, to metabolic syndrome, crowd improves comprehensively comprehensively.Improve life quality.
2, kidney injury is repaired
Marine bioactivity polysaccharide or oligosaccharides and Cordyceps militaris and corn stigma effectively reduce Urine proteins and blood inosine, uric acid, urea nitrogen; and the renal cells of damaged can be made to be repaired; thus improve Status of Anemia, protect kidney, improve renal function, help impaired kidney restore funcitons.
3, blood acid-base balance is improved
Marine bioactivity polysaccharide or oligosaccharides can improve body inner acidic environment, make the body fluid of people (mainly blood) maintain healthy alkalescence state all the time.PH Zhi Approximately is 7.3 to 7.5) in; And the normal circulation that metabolic function regulates blood and tissue fluid can be increased, dissolve nutrient, make it easily and absorb and transport, help discarded object in excretion body, also can improve the sour environment of urine simultaneously.
4, develop immunitypty
Marine active polysaccharide in the present invention's formula or oligosaccharides, physiological activator wherein has effect, seawood meal, Cordyceps militaris, the burdock of building up resistance also can improve immunity of organisms.The factor of the many aspects such as the synergy of marine active polysaccharide or oligosaccharide kind material and the several functions factor, obviously can strengthen the resistivity of body, reduces the generation of the complication such as infection.
5, absorption is easy to more scientific
Utilize formula of the present invention to make particle tea-drinking, it meets the feature of metabolic syndrome " a six high fat " crowd's physiological metabolism circulation, in isotonic state after a certain amount of water-soluble solution, can arrive small intestine, absorb fast, enter blood, better effects if quickly through stomach!
Detailed description of the invention
Following examples are only for setting forth the present invention, and protection scope of the present invention is not only confined to following the implementation of Formulation Example.The those of ordinary skill of described technical field, according to above content disclosed by the invention and scope that each parameter is got, all can realize object of the present invention.
Embodiment 1
Preparation improves marine bioactivity polysaccharide or the oligosaccharides particle tea-drinking of metabolic syndrome " a six high fat ".
The present embodiment selects powdery alga oligosaccharides, chitosan oligosaccharide, kelp powder, Cordyceps militaris, the leaf of bamboo, burdock, corn stigma, presses row weight proportion and is prepared:
(1) marine bioactivity polysaccharide or oligosaccharides: alga oligosaccharides 0.3g, chitosan oligosaccharide 0.2g;
(2) seawood meal: kelp powder 0.5g;
(3) Cordyceps militaris: 0.5g;
(4) leaf of bamboo: 0.05g;
(5) burdock: 0.5g;
(6) corn stigma: 0.5g.
Mixed by above-mentioned raw materials, uniform stirring, cross granulation, drying, whole grain, makes graininess.After dissolving with 200m1 ~ 500ml, steep to 2 ~ 10 minutes, directly drink.
Embodiment 2
Preparation improves marine bioactivity polysaccharide or the oligosaccharides particle tea-drinking of metabolic syndrome " a six high fat ".
The present embodiment selects powdery alga oligosaccharides, kelp powder, Cordyceps militaris, the leaf of bamboo, burdock, corn stigma, presses row weight proportion and is prepared:
(1) marine bioactivity polysaccharide or oligosaccharides: alga oligosaccharides 1g;
(2) seawood meal: kelp powder 0.3g;
(3) Cordyceps militaris: 0.65g;
(4) leaf of bamboo: 0.05g;
(5) burdock: 1g;
(6) corn stigma: 1g.
Above-mentioned raw materials is mixed, stirs, through granulation, granulate.Be distributed into tea in bag.Brew 2 ~ 10 minutes with 200ml ~ 500ml, repeatedly can add bubble drink.
Embodiment 3
Preparation improves marine bioactivity polysaccharide or the oligosaccharides particle tea-drinking of metabolic syndrome " a six high fat ".
The present embodiment selects powdery alga oligosaccharides, ammonia sugar, kelp powder, Cordyceps militaris, the leaf of bamboo, burdock, corn stigma, presses row weight proportion and is prepared:
(1) marine bioactivity polysaccharide or oligosaccharides: alga oligosaccharides 0.5g, ammonia sugar 0.5g;
(2) seawood meal: kelp powder 0.3g;
(3) Cordyceps militaris: 0.65g;
(4) leaf of bamboo: 0.05g;
(5) burdock: 1g;
(6) corn stigma: 1g.
Mixed by above-mentioned raw materials, uniform stirring, cross granulation, drying, whole grain, makes graininess.After dissolving with 200ml ~ 500ml, steep to 2 ~ 10 minutes, directly drink.
Embodiment 4
Preparation improves marine bioactivity polysaccharide or the oligosaccharides particle tea-drinking of metabolic syndrome " a six high fat ".
The chitosan of the present embodiment selection powdery, agar, kelp powder, Cordyceps militaris, the leaf of bamboo, burdock, corn stigma, press row weight proportion and be prepared:
(1) marine bioactivity polysaccharide or oligosaccharides: chitosan 1g, agar 1g;
(2) seawood meal: kelp powder 0.3g;
(3) Cordyceps militaris: 0.65g;
(4) leaf of bamboo: 0.05g;
(5) burdock: 0.5g;
(6) corn stigma: 0.5g.
Mixed by above-mentioned raw materials, uniform stirring, cross granulation, drying, whole grain, makes graininess.After dissolving with 200ml ~ 500ml, steep to 2 ~ 10 minutes, directly drink.
Embodiment 5
Preparation improves marine bioactivity polysaccharide or the oligosaccharides particle tea-drinking of metabolic syndrome " a six high fat ".
The present embodiment selects powdery chitosan oligosaccharide, kelp powder, Cordyceps militaris, the leaf of bamboo, burdock, corn stigma, presses row weight proportion and is prepared:
(1) marine bioactivity polysaccharide or oligosaccharides: chitosan oligosaccharide 1g;
(2) seawood meal: kelp powder 0.3g;
(3) Cordyceps militaris: 0.65g;
(4) leaf of bamboo: 0.05g;
(5) burdock: 1g;
(6) corn stigma: 1g.
Mixed by above-mentioned raw materials, uniform stirring, cross granulation, drying, whole grain, makes graininess.After dissolving with 200ml ~ 500ml, steep to 2 ~ 10 minutes, directly drink.
Embodiment 6
Preparation improves marine bioactivity polysaccharide or the oligosaccharides particle tea-drinking of metabolic syndrome " a six high fat ".
The present embodiment selects powdery algal polysaccharides, kelp powder, Cordyceps militaris, the leaf of bamboo, burdock, corn stigma, presses row weight proportion and is prepared:
(1) marine bioactivity polysaccharide or oligosaccharides: algal polysaccharides 3g;
(2) seawood meal: kelp powder 4g;
(3) Cordyceps militaris: 1.5g;
(4) leaf of bamboo: 0.5g;
(5) burdock: 1.5g;
(6) corn stigma: 2.0g.
Mixed by above-mentioned raw materials, uniform stirring, cross granulation, drying, whole grain, makes graininess.After dissolving with 200ml ~ 500ml, steep to 2 ~ 10 minutes, directly drink.
Claims (10)
1. for improving marine bioactivity polysaccharide or the oligosaccharides particle tea-drinking of metabolic syndrome " a six high fat ", it is characterized in that, its material component comprises: marine bioactivity polysaccharide or oligosaccharides, seawood meal, Cordyceps militaris, burdock, the leaf of bamboo, corn stigma, and each material component is prepared by weight ratio: marine bioactivity polysaccharide or oligosaccharides 0.5 ~ 3.0, seawood meal 0.5 ~ 4.0, Cordyceps militaris 0.5 ~ 1.5, burdock 0.5 ~ 1.5, the leaf of bamboo 0.05 ~ 0.5, corn stigma 0.5 ~ 2.0; Described marine bioactivity polysaccharide or oligosaccharides, comprise marine bioactivity polysaccharide or marine bioactivity oligosaccharides.
2. tea-drinking as claimed in claim 1, it is characterized in that, described marine bioactivity polysaccharide or oligosaccharides are any one in algal polysaccharides, alga oligosaccharides, ocean shell class polysaccharide, ocean shell class oligosaccharides, marine animal and microbial polysaccharide and marine animal and microbial oligosaccharide, several or whole;
Described algal polysaccharides or oligosaccharides are any one in algal polysaccharides, alga oligosaccharides, sodium alginate, fucoidin and agar, several or whole;
Described ocean shell class polysaccharide or oligosaccharides, in chitosan, chitin oligo saccharide, sea urchin shell polysaccharide, pearl powder, nacreous layer powder, shitosan, chitosan oligosaccharide and ammonia sugar any one, several or whole;
Described marine animal and microbial polysaccharide or oligosaccharides are any one in marine microalgae polysaccharide or oligosaccharides, glycosaminoglycan, sea cucumber polysaccharide, several or whole.
3. tea-drinking as claimed in claim 1, it is characterized in that, described seawood meal comprises: in chlorella powder, Dunaliella peircei powder, ulva lactuca powder, Kelp Powder, skirt dish powder, laver powder, kelp powder, Algemin, pelvetia silquosa powder and Eucheuma powder any one, several or whole.
4. the tea-drinking as described in claim 1,2 or 3, is characterized in that, selects powdery alga oligosaccharides, chitosan oligosaccharide, kelp powder, Cordyceps militaris, the leaf of bamboo, burdock, corn stigma, presses row weight proportion and be prepared:
(1) marine bioactivity polysaccharide or oligosaccharides: alga oligosaccharides 0.3g, chitosan oligosaccharide 0.2g;
(2) seawood meal: kelp powder 0.5g;
(3) Cordyceps militaris: 0.5g;
(4) leaf of bamboo: 0.05g;
(5) burdock: 0.5g;
(6) corn stigma: 0.5g.
5. the tea-drinking as described in claim 1,2 or 3, is characterized in that, selects powdery alga oligosaccharides, kelp powder, Cordyceps militaris, the leaf of bamboo, burdock, corn stigma, presses row weight proportion and be prepared:
(1) marine bioactivity polysaccharide or oligosaccharides: alga oligosaccharides 1g;
(2) seawood meal: kelp powder 0.3g;
(3) Cordyceps militaris: 0.65g;
(4) leaf of bamboo: 0.05g;
(5) burdock: 1g;
(6) corn stigma: 1g.
6. the tea-drinking as described in claim 1,2 or 3, is characterized in that, selects powdery alga oligosaccharides, ammonia sugar, kelp powder, Cordyceps militaris, the leaf of bamboo, burdock, corn stigma, presses row weight proportion and be prepared:
(1) marine bioactivity polysaccharide or oligosaccharides: alga oligosaccharides 0.5g, ammonia sugar 0.5g;
(2) seawood meal: kelp powder 0.3g;
(3) Cordyceps militaris: 0.65g;
(4) leaf of bamboo: 0.05g;
(5) burdock: 1g;
(6) corn stigma: 1g.
7. the tea-drinking as described in claim 1,2 or 3, is characterized in that, selects the chitosan of powdery, agar, kelp powder, Cordyceps militaris, the leaf of bamboo, burdock, corn stigma, presses row weight proportion and be prepared:
(1) marine bioactivity polysaccharide or oligosaccharides: chitosan 1g, agar 1g;
(2) seawood meal: kelp powder 0.3g;
(3) Cordyceps militaris: 0.65g;
(4) leaf of bamboo: 0.05g;
(5) burdock: 0.5g;
(6) corn stigma: 0.5g.
8. the tea-drinking as described in claim 1,2 or 3, is characterized in that, selects powdery chitosan oligosaccharide, kelp powder, Cordyceps militaris, the leaf of bamboo, burdock, corn stigma, presses row weight proportion and be prepared:
(1) marine bioactivity polysaccharide or oligosaccharides: chitosan oligosaccharide 1g;
(2) seawood meal: kelp powder 0.3g;
(3) Cordyceps militaris: 0.65g;
(4) leaf of bamboo: 0.05g;
(5) burdock: 1g;
(6) corn stigma: 1g.
9. the tea-drinking as described in claim 1,2 or 3, is characterized in that, selects powdery algal polysaccharides, kelp powder, Cordyceps militaris, the leaf of bamboo, burdock, corn stigma, presses row weight proportion and be prepared:
1) marine bioactivity polysaccharide or oligosaccharides: algal polysaccharides 3g;
(2) seawood meal: kelp powder 4g;
(3) Cordyceps militaris: 1.5g;
(4) leaf of bamboo: 0.5g;
(5) burdock: 1.5g;
(6) corn stigma: 2.0g.
10. as claim 1 ~ 9 arbitrary as described in tea-drinking, it is characterized in that, each material component mix keep its powdery or through granulation, press grain, make graininess or make tea in bag, with boiling water Instant Drinks or bubble drink.
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