CN104399003A - 一种治疗肺气肿的中药 - Google Patents
一种治疗肺气肿的中药 Download PDFInfo
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Abstract
本发明公开了一种治疗肺气肿的中药,属于中药技术领域,由下述原料制备而成:麦冬,厚朴,白芥子,陈皮,贝母,菖蒲,郁金,泽泻,桂枝,苍术,白术,知母,败酱草,丹皮,黄芪,党参,沙参,桃仁,鱼腥草,益母草,五味子,当归。本发明药物组合后,药物具有协同作用,具有柔肝熄风、清热解毒、肃肺平喘、化痰通络之功能,能提高机体的免疫力,增强人体抗病能力,疗效确切,见效快,疗程短、愈后不复发。
Description
技术领域
本发明涉及一种治疗肺气肿的中药,属中药领域。
背景技术
肺气肿是指终末细支气管远端(呼吸细支气管、肺泡管、肺泡囊和肺泡)的气腔弹性减退,过度膨胀、充气和肺容积增大。由于支气管慢性炎症,气道阻力增加,终末细支气管远端气腔过度膨胀伴有气腔壁的破坏,逐步形成慢性肺气肿,进而影响通气和气体交换的功能。诱发肺气肿的原因很多,包括感染、吸烟、大气污染、职业性粉尘和有害气体的长期吸入、过敏等。肺气肿主要表现为咳嗽、痰多、气急、胸闷、呼吸困难,并随肺气肿程度的逐渐发展而呈进行性加重。晚期常因合并感染而使病情迅速恶化,发生呼吸衰竭或心力衰竭而危及生命。
目前肺气肿的治疗主要依靠西医,常用青霉素类、氨基糖苷类、喹诺酮类及头孢菌素类抗生素类药,和氨茶碱、β2受体***等舒张支气管的药物,病情严重的加以激素药,这些药物可以快速改善症状,但治标不治本,往往导致患者终身服药,而这些药物普遍毒副作用大,长期服用会严重损害患者的肝、肾功能,导致患者病情一年比一年加重。服用中药治疗,能达到痊愈之目的,不过现有的组方存在疗效不明显,疗程相对过长等问题。
发明内容
本发明的目的在于克服现有治疗的不足,而提供一种治疗肺气肿的中药,该中药组合物治疗肺气肿治愈率高、见效快,且毒副作用少。
本发明解决技术问题所采取的技术方案是:一种治疗肺气肿的中药,其特征是,由以下重量的中药制成:
麦冬10-20克,厚朴10-20克,白芥子10-20克,陈皮10-20克,贝母10-20克,菖蒲10-20克,郁金10-20克,泽泻10-20克,桂枝10-20克,苍术10-20克,白术10-20克,知母10-20克,败酱草10-20克,丹皮10-20克,黄芪10-20克,党参10-20克,沙参10-20克,桃仁10-20克,鱼腥草15-25克,益母草15-25克,五味子3-8克,当归3-8克。
优选的,由以下重量的中药制成:
麦冬10克,厚朴10克,白芥子10克,陈皮10克,贝母10克,菖蒲10克,郁金10克,泽泻10克,桂枝10克,苍术15克,白术15克,知母15克,败酱草15克,丹皮15克,黄芪15克,党参15克,沙参15克,桃仁15克,鱼腥草20克,益母草20克,五味子6克,当归6克。
配制及服用方法:
制备及服用方法:水煎煮,分两次早晚服用。1个月为1个疗程。
各中药的药理作用:
麦冬:甘,微苦,微寒。归心、肺、胃经。养阴生津,润肺清心。用于肺燥干咳,虚痨咳嗽,津伤口渴,心烦失眠,内热消渴,肠燥便秘,咽白喉。
厚朴:苦辛,温。入脾、胃、大肠经。有化湿导滞、行气平喘、驱风镇痛的功效。
白芥子:辛、温,归肺经。温肺散结,通经止痛。本品辛温气锐。咳豁痰延,利气机,胸痛,通经络,凡痰阻气滞,咳逆胁痛或痰滞经络,肢体疼痛等证,均可配伍应用。
陈皮:性温,味苦、辛。理气健脾,燥湿化痰。用于胸脘胀满、食少吐泻、咳嗽多痰。
贝母:味大苦,性寒。入手太阴、少阳,足阳明、厥阴。清热化痰,散结解毒。治风热咳嗽,肺痈喉痹,瘰疬,疮疡肿毒。
菖蒲:辛、温、无毒。治癫阐风疾,喉痹肿痛。食积,气积,肺损吐血,赤白带下,产后流血不止,病后耳聋,痈疸,热毒湿疮。
郁金:辛苦,凉。入心、肺、肝经。行气解郁,凉血破瘀,治胸腹胁肋诸痛,失心癫狂,热病神昏.吐血,黄疸。
泽泻:甘,寒。入肾、膀胱经。利水,渗湿,泄热。治小便不利,水肿胀满,呕吐,泻痢,痰饮,脚气,淋病,尿血。
桂枝:辛甘,温。入膀胱、心、肺经。发汗解肌,温经通脉。治风寒表证,肩背肢节酸疼,胸痹痰饮,经闭癥瘕。
苍术:辛苦,温。入脾、胃经。健脾,燥湿,解郁,辟秽。治湿盛困脾,倦怠嗜卧,脘痞腹胀,食欲不振,呕吐,泄泻,痢疾,疟疾,痰饮,水肿,时气感冒,风寒湿痹,足痿,夜盲。
白术:苦甘,温。入脾、胃经。补脾,益胃,燥湿,和中,安胎。治脾胃气弱,不思饮食,倦怠少气,虚胀,泄泻,痰饮,水肿,黄疸,湿痹,小便不利,头晕,自汗,胎气不安。
知母:苦,寒。入肺、胃、肾经。滋阴降火,润燥滑肠。治烦热消渴,骨蒸劳热,肺热咳嗽,大便燥结,小便不利。
败酱草:性味性凉,味辛、苦。清热解毒,祛瘀排脓。用于阑尾炎、痢疾、肠炎、肝炎、眼结膜炎、产后瘀血腹痛、痈肿疔疮。
丹皮:清热,凉血,和血,消瘀。治热入血分,发斑,惊痫,吐、衄、便血,骨蒸劳热,经闭,癥瘕,痈疡,扑损。
黄芪:性温,味甘。补气升阳,益卫固表、托毒生肌、利水退肿。主治脾胃虚弱,食少倦怠,气虚血脱,表虚自汗、盗汗。
党参:甘,平。入手、足太阴经气分。补中益气,生津,养血。用于中气不足的体虚倦怠,脾胃虚弱,气血两亏,治体倦无力,肺气亏虚。治食少,口渴,久泻,脱肛。及气血双亏的面色萎黄,头晕心悸等。
沙参:苦、微寒、无毒。主治肺热咳嗽。突然发疝,小腹及阴中绞痛,妇女白带。
桃仁:苦甘,平。入心、肝、大肠经。破血行瘀,润燥滑肠。治经闭,癥瘕,热病蓄血,风痹,疟疾,跌打损伤,瘀血肿痛,血燥便秘。
鱼腥草:辛,寒。入肝、肺二经。清热解毒,利尿消肿。治肺炎,肺脓疡,热痢,疟疾,水肿,淋病,白带,痈肿,痔疮,脱肛,湿疹,秃疮,疥癣。
益母草:辛苦,凉。入心包、肝经。活血,祛瘀,调经,消水。治***,胎漏难产,胞衣不下,产后血晕,瘀血腹痛,崩中漏下,尿血,泻血,痈肿疮疡。
五味子:酸,温。入肺、肾经,敛肺,滋肾,生津,收汗,涩精。治肺虚喘咳,口干作渴,自汗,盗汗,劳伤羸瘦,梦遗滑精,久泻久痢。
当归:甘辛,温。入心、肝、脾经。补血和血,调经止痛,润燥滑肠。治***,经闭腹痛,癥瘕结聚,崩漏;血虚头痛,眩晕,痿痹;肠燥便难,赤痢后重;痈疽疮窃,跌扑损伤。
中医学将慢性阻塞性肺气肿归为“肺胀”的范畴。中医辨证认为该病多由中气衰弱,形体羸弱,本元虚弱,加之痰热、血瘀、水饮及外邪等影响导致患者发病。所以中医认为慢性阻塞性肺气肿属于本虚标实证。该病的病位在肺,进而对脾、肾产生影响,甚至会影响到心及其它脏腑。
本发明药物组合后,药物具有协同作用,具有柔肝熄风、清热解毒、肃肺平喘、化痰通络之功能,能提高机体的免疫力,增强人体抗病能力,疗效确切,见效快,疗程短、愈后不复发。
以下结合临床资料及典型病例对本发明的有益效果进一步说明。
一、临床观察
1、临床资料
选取2012年4月至2013年5月期间,某医院收治的肺气肿患者60例,其中男29例,女31例;年龄32-81岁,平均为(58±1.5)岁;病程1~16年。将60例患者按治疗方法分为两组,治疗组30例,对照组30例。治疗组年龄32-78岁,平均为(55±2岁);对照组年龄35-81岁,平均为(59±2岁)。同时对患者生活环境、临床症状、病情等基本生活资料进行研究分析,将患者的一般资料进行统计学分析,P=0.063>0.05,无显著统计学差异,具有可比性。
2、诊断标准:
①咳嗽、咳痰:患者多有咳嗽频繁,痰多,严重者常年不断;
②呼吸困难,病情迁延:慢性阻塞性肺气肿患者在咳嗽咳痰的基础上多伴有呼吸困难且逐渐加重,甚至会导致呼吸衰竭;
体征:肺气肿患者早期无明显体征。随病情发展可出现桶状胸,叩诊呈过清音,心浊时界缩小。引发肺部感染时可出现紫绀;
辅助检查:呼吸功能检查,X线检查,血液气体分析等对于慢性阻塞性肺气肿有重要的诊断价值。
3、治疗方法:
治疗组:服用本发明药物,水煎煮,分两次早晚服用。1个月为1个疗程。
对照组:吸入异丙托溴胺,40μg/次,3次/日;同时口服复方氨茶碱,1粒/次,1次/日。1个月为1个疗程。
根据患者病情连续治疗1-2个疗程后进行疗效评价。
4、疗效标准:
痊愈:患者咳嗽、气喘等症状消失,听诊肺部的哕音消失;
有效:患者咳嗽、气喘等症状明显减轻,听诊肺部哕音减轻,但仍有部分症状未消失;
无效:患者咳嗽、气喘等临床症状无明显改善甚至加重。听诊肺部哕音无明显改变。
5、治疗结果:见对照表1。
表1两组临床疗效对照表
组别 | 病例(人) | 临床痊愈 | 有效 | 无效 | 总有效率(%) |
治疗组 | 30 | 24 | 5 | 1 | 96.7 |
对照组 | 30 | 11 | 12 | 7 | 76.7 |
6、结论:对比两组患者治疗效果,观察组患者总有效率为96.7%,效果明显优于对照组的76.7%,结果表明,本发明药物治疗肺气肿疗效显著,且未发现有毒副作用。
二、典型病例:
病例1,成某某,男,61岁。患者因严重气促,端坐呼吸不能平卧,频繁干咳,近日咳嗽加剧伴发热,口服抗生素无效,去医院治疗,在医院被诊断为肺气肿。服用本方一个疗程后,病人的危机症状得到了缓解,又服药一个疗程,所有不适症状消失,至今情况良好。
病例2,仲某某,女,55岁。患者患有多年的气管炎,最近常痉挛性咳嗽、咳嗽喘憋、呼吸困难,在当地医院被诊断为患上肺气肿。服用该种治疗肺气肿的药物2疗程,咳嗽喘憋症状减轻,继续服药2个疗程,病人呼吸困难、咳嗽症状消失,又经1个疗程的治疗后痊愈。
具体实施方式
实施例1:一种治疗肺气肿的中药,由以下重量的中药制成:
麦冬10克,厚朴10克,白芥子10克,陈皮10克,贝母10克,菖蒲10克,郁金10克,泽泻10克,桂枝10克,苍术15克,白术15克,知母15克,败酱草15克,丹皮15克,黄芪15克,党参15克,沙参15克,桃仁15克,鱼腥草20克,益母草20克,五味子6克,当归6克。
配制及服用方法:
制备及服用方法:水煎煮,分两次早晚服用。1个月为1个疗程。
实施例2:一种治疗肺气肿的中药,由以下重量的中药制成:
麦冬10克,厚朴10克,白芥子10克,陈皮10克,贝母10克,菖蒲10克,郁金10克,泽泻12克,桂枝12克,苍术12克,白术12克,知母12克,败酱草12克,丹皮15克,黄芪15克,党参15克,沙参15克,桃仁15克,鱼腥草20克,益母草20克,五味子6克,当归6克。
配制及服用方法:同例1。
实施例3:一种治疗肺气肿的中药,由以下重量份的中药制成:
麦冬10克,厚朴10克,白芥子10克,陈皮10克,贝母10克,菖蒲10克,郁金10克,泽泻10克,桂枝10克,苍术10克,白术10克,知母10克,败酱草15克,丹皮15克,黄芪20克,党参20克,沙参15克,桃仁15克,鱼腥草20克,益母草20克,五味子5克,当归3克。
配制及服用方法:同例1。
Claims (2)
1.一种治疗肺气肿的中药,其特征是,由以下重量的中药制成:
麦冬10-20克,厚朴10-20克,白芥子10-20克,陈皮10-20克,贝母10-20克,菖蒲10-20克,郁金10-20克,泽泻10-20克,桂枝10-20克,苍术10-20克,白术10-20克,知母10-20克,败酱草10-20克,丹皮10-20克,黄芪10-20克,党参10-20克,沙参10-20克,桃仁10-20克,鱼腥草15-25克,益母草15-25克,五味子3-8克,当归3-8克。
2.根据权利要求1所述的治疗肺气肿的中药,其特征是,由以下重量份的中药制成:
麦冬10克,厚朴10克,白芥子10克,陈皮10克,贝母10克,菖蒲10克,郁金10克,泽泻10克,桂枝10克,苍术15克,白术15克,知母15克,败酱草15克,丹皮15克,黄芪15克,党参15克,沙参15克,桃仁15克,鱼腥草20克,益母草20克,五味子6克,当归6克。
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