CN104387684A - Medical PS (Poly Styrene) antibacterial film and preparation method thereof - Google Patents

Abstract

The invention discloses a medical PS (Poly Styrene) antibacterial film and a preparation method thereof. The preparation method comprises the following steps: weighting the following components in parts by weight: PS, CPE (Chlorinated Polyethylene), a nanometer zirconium phosphate silver-loaded antibacterial agent, nanometer LDPE (Low-Density Polyethylene), a styrene-butadiene block copolymer, SEBS (Styrene-Ethylene/Butylene-Styrene), a surface treatment agent, LDPE, dicumyl peroxide, POE (Polyolefin Elastomer), an ultraviolet absorber, N,N-diethylethanolamine, aluminum trichloride, zinc stearate and carbon tetrachloride, evenly mixing and extruding and granulating. At 0 DEG C, the product has longitudinal elongation of 5-45% and tensile strength of 45-65MPa, longitudinal heat shrinkage of 25-45%, transverse shrinkage ratio of 20-40% and tear strength of 10-12kN/m; the antibacterial rate on escherichia coli is 95.9-99.9% and the antibacterial rate on staphylococcus aureus is 97.5-99.5%.

Description

A kind of medical PS antibacterial film and preparation method thereof

Technical field

The application belongs to medical new material technology field, particularly relates to a kind of medical PS antibacterial film and preparation method thereof.

Background technology

Biomedical material refers to a class and has property, features, for artificial organs, surgical repair, physiotherapy and rehabilitation, diagnosis, treatment illness, and can not produce dysgenic material to tissue.Present various synthetic materials and natural macromolecular material, metal and alloy material, pottery and carbon materials and various matrix material, it is made product and has been widely used in clinical and scientific research.The research of Chinese medical macromolecular material starts to walk comparatively early, development is very fast.About You50Duo Ge unit is engaged in the research of this respect at present, existing medical macromolecular materials kind more than 60, and goods reach more than 400 and plant, and the polymethylmethacrylate for medical treatment reaches 300 t every year.But the research of Chinese medical macromolecular material is still in experience and semiempirical stage [5] at present, does not also have can be based upon on the basis of molecular designing.Therefore, should with the structure and theory of material, the chemical constitution of material, the pass between surface properties and the consistency of life entity tissue are according to researching and developing novel material.Along with the development of biotechnology, the scientist of different subject has carried out broad co-operation, thus the artificial organs making manufacture have complete biological function shows fine prospect.The reparation in tissue and device palace, will fixedly develop into regeneration from simply utilizing appliance mechanisms and rebuild lived tissue and device palace; Permanent reparation and replacement is developed to from the reparation of short-life tissue and organ.This Medical Revolution (particularly surgery), proposes many demands to the development of the related disciplines such as life profit and material, creates important promoter action to the development of biomedical material.The suggestion bio-medical material bio-medical material of developing china biomedical material is the important branch of Materials Science and Engineering, and its maximum feature is that subject crossing is extensive, application potential is huge, challenge is strong.Along with novel material, new technology, the continuing to bring out of new opplication, attract many scientists to throw the research in this field of people, become current materialogy and study one of most active field.In China, although the research of biomedical material obtains the achievement that some attract people's attention, integral level is not high, and follow-up study is many, and source treatment is few.In industrialization, biomedical material and goods thereof account for the share of world market less than 2%, mainly rely on import, and product technology structure and level are in the junior stage substantially.In conjunction with China's actual conditions and discipline development trend, according to the principle of " doing something more important by leaving the others undone, key breakthrough ", we advise, should carry out primary study in five.One is the design of biological structure and biological function and builds principle research.Study emphatically the design of the base materials such as bone, cartilage and the tendon with inducing tissue regeneration and skeleton construction and bionical assembling thereof; Two is the interaction mechanism research of surface/interface process-between material and body.From cell and molecular level further investigation material and specific cells, organize between surface/interface effect, announcement affects factor and the essence of biocompatibility.Three is controlled release study mechanism of bio-guide and biologically active substance.Study design and the bio-guide principle of the material of the specific bioactive materials such as self controllable or Targeting delivery albumen, gene; For the design of the semi-permeable polymeric film of histocyte and gene therapy, self-assembly and specific cell packing technique; Four be biological degradation/absorption regulatory mechanism research.The impact that the molecular structure of research biological degradation/absorbing material and coenocorrelation are degraded on it, the regulation and control of degraded/absorption rate, degraded/absorption and metabolism mechanism, and degraded product is on the impact of body.Its target is for the having of one's own of engineered artificial organs biomaterial and drug release material, method of modifying are provided fundamental basis, and realizes the object that material participates in vital process and builds vital tissues.Five is preparation method and the quality control system research of material.The computer aided design (CAD) of main research bio-medical material and dummy; By carrying out of above-mentioned research, will the research level of Chinese biological material be improved a lot, for solid basis is established in the development of Chinese biological medical material science and industry thereof.Bio-medical material has made major contribution for saving life and improving people ' s health level, is currently faced with important breakthrough.After China's entry into the WTO, bio-medical material industry will face more challenges and more opportunity, and biomaterial scientific worker shoulder heavy responsibilities.We believe, under the support energetically of country, trans-departmental, interdiscipline is worked in concert, by walking to rely on one's own efforts the development combined with technology introduction, in, molecular designing, human simulation, intelligent medicine controlled releasing etc. engineered at biomaterial, emphasis throws people, bio-medical material will be the standard of living comprehensively improving people, promotes the well-being of mankind and makes larger contribution.

Medical macromolecular materials are the polymer materialss manufacturing human body viscera, vitro in organ, pharmaceutical dosage form and medicine equipment.Over 20 years, the macromolecular material for this respect has polyvinyl chloride, natural rubber, polyethylene, polymeric amide, polypropylene, polystyrene, silicon rubber, polyester, tetrafluoroethylene, polymethylmethacrylate and urethane etc.Mainly contain artificial organs, medicine equipment and pharmaceutical dosage form three types.Artificial organs, comprises internal organ and device outside.Internal organ: have substitute blood vessels, artificial heart, heart valve prosthesis, cardiac repair, artificial esophagus, artificial choledochus, artificial urethra, artificial peritonaeum, hernia supporting material, artificial bone and joint prosthesis, artificial blood plasma, artificial tendon, artificial skin, lift face material and schrittmacher etc.2. vitro in organ and device: have heart lung machine, artificial lung, kidney machine, artificial liver, artificial spleen, paralysis limb stimulator, electronics artificial limb, pseudodont, artificial eye, wig, false ear, do evil through another person, pseudopod etc.Medicine equipment, general curative and nurse apparatus, as eye band, casing flusher, entry needle, stethoscope, rectoscope, eye lotion dropper, abdominal belt and connecting piece etc.; Anesthesia and operating room furniture, as suction pump, suture, pharynx mirror, intravascular injection apparatus etc.; Check and inspection chamber apparatus, as the electrode, developmental tube, culture dish etc. of heparin tube, blood collecting bottle, electrocardiogram(ECG.Pharmaceutical dosage form, the auxiliary agent of medicine: macromolecular material itself is inertia, does not participate in the effect of medicine, only plays the effects such as thickening, surfactivity, disintegration, bonding, figuration, lubrication and packaging, or in human body, play " Drug Storage " effect, drug slow is released and prolong drug action time.Polymeric medicine: by low-molecule drug, makes molecular vehicle with inertia water-soluble polymers, the low molecular compound with the property of medicine, is connected, makes polymeric medicine by covalent linkage or ionic linkage with the side base of carrier.

Antibiotic plastic be a class in environment for use itself to stain bacterium on plastics, mould, the female bacterium of alcohol, algae even virus etc. rise and suppress or the plastics of killing action, keep itself clean by suppressing the breeding of microorganism.At present, antibiotic plastic obtains mainly through the method for adding a small amount of antiseptic-germicide in common plastics.First antibiotic plastic will meet the exclusive requirement to performances such as its physics, chemistry, machineries when plastics use as basic material in using, will consider to possess the requirement of this specific function antibacterial and consequent additional factor simultaneously.The research of Chinese medical macromolecular material starts to walk comparatively early, development is very fast.About You50Duo Ge unit is engaged in the research of this respect at present, existing medical macromolecular materials kind more than 60, and goods reach more than 400 and plant, and the poly-methyl PS acid methyl esters for medical treatment reaches 300t every year.But the research of Chinese medical macromolecular material is still in experience and semiempirical stage at present, does not also have can be based upon on the basis of molecular designing.Therefore, should with the structure and theory of material, the chemical constitution of material, the pass between surface properties and the consistency of life entity tissue are according to researching and developing novel material.Medical macromolecular materials will be applied to organism must will meet the strict requirement such as biological functionality, biocompatibility, chemical stability and workability simultaneously.Development trend, research and development meet biocompatibility and blood compatibility material, attach most importance to polyolefine, polysiloxane, fluorocarbon polymer and urethane; Exploitation Drug controlled release, artificial organ, medicine equipment and control fertility material therefor.Development of small-scale, Portable belt, in the artificial organs device of the type such as burying.

Polystyrene (Polystyrene, abbreviation PS) refers to the polymkeric substance synthesized through free radical polymerization by styrene monomer, and japanese name is Port リ ス チ レ Application.It is a kind of water white thermoplastics, has the glass transition temp higher than 100 DEG C, is therefore often used to make the various one-trip container needing to bear the temperature of boiling water, and disposable foam food boxes etc.Polystyrene (PS) comprises ordinary polystyrene, polystyrene foamed (EPS), high-impact polystyrene (HIPS) and syndiotactic polystyrene (SPS).Ordinary polystyrene resin is nontoxic, odorless, colourless transparent grain, like glassy hard brittle material, its goods have high transparency, and transmittance can reach more than 90%, and electrical insulation capability is good, easy coloring, processing fluidity is good, good rigidly and chemical resistance good etc.The being property of weak point of ordinary polystyrene is crisp, and shock strength is low, easily occurs stress cracking, poor heat resistance and not resistance to boiling water etc.Ordinary polystyrene resin belongs to amorphous macromolecule polymkeric substance, the side base of polystyrene macromolecular chain is phenyl ring, large volume side base is the physicochemical property that the random arrangement of phenyl ring determines polystyrene, as transparency is high. and rigidity is large. and second-order transition temperature is high, and property is crisp.Expandable Polystyrene (EPS) is made for flooding lower boiling pneumatogen in ordinary polystyrene, by heat foamable in the course of processing, is exclusively used in making foam article.High-impact polystyrene is the multipolymer of vinylbenzene and divinyl, and divinyl is disperse phase, improve the shock strength of material, but product is opaque.Syndiotactic polystyrene is isostructure, and adopt metallocene catalyst to produce, the polystyrene new variety of development, performance is good, belongs to engineering plastics.It is by multiple isolation technique by plastic raw materials or plastics that plastics detect, high-tech analytical instrument is utilized to detect, the result then detected by plastics, by the reverse derivation through technician, finally carries out process that is qualitative, rational judgment to the non-principal component of complete paired samples.Technician is except relying on sophisticated equipment support in this process, also must have abundant domain knowledge and knowwhy simultaneously.

Polystyrene (PS) is a kind of thermoplastic resin, due to its cheap and easy machine-shaping, is therefore able to widespread use.Polystyrene have homopolymer (transparent pellet) or toughness reinforcing graft copolymer or with elastomeric mixture (High Impact Polystyrene (HIPS) IPS) form.Polystyrene copolymer increases than homopolymer in physicals and thermal characteristics.This few class polystyrene has multiple grade, as standard I PS and standard transparent grade, environmental stress crack resistance grade (ESCR), UV resistant level.The high flexible grade of flame retardant grade, wear-resisting level, lightweight product processed, the grade that can foam, super elementary and low residual volatiles grade etc.Polystyrene resin is for the manufacture of the disposable tableware in daily life, trolley part, wrapping material, toy, material of construction, electrical equipment and household supplies etc.Greatly develop the production of Materials Styrene, thoroughly solve the problem that polystyrene raw material lacks.Insufficient raw material constrains the development that polystyrene is produced, and therefore solving raw material problem is one of key of development polystyrene production.According to prediction, by 2005, domestic polystyrene throughput will reach 2,200,000 tons, within 2010, will reach 3,000,000 tons, very large to cinnamic demand, and the production of styrene ability of planning still can not be satisfied the demand.Polystyrene provides the good opportunity of development production of styrene to oil and company of petrochemical industry two large group to cinnamic huge demand, two companies of large group are domestic important production of styrene business, expand cinnamic throughput as possible both to furnish ample material for the production of domestic polystyrene, can take advantage of the occasion again to dominate the market, obtain good economic benefit.Seize the opportunity, actively capture domestic market.Country sternly cracks down on smuggling in recent years, specification import, for the consideration reduced costs, the user of more domestic original use imported raw material starts to find the domestic vendors that can replace imported product, and this brings capital chance to domestic polystyrene manufacturing enterprise.Domestic polystyrene manufacturing enterprise should seize the opportunity, and makes great efforts to enhance product performance and quality, strives import substitutes in maximum range.In a word, as long as take appropriate measures, domestic polystyrene is produced can obtain good development completely.The attitude abandoned easily is taked to be worthless.China's homemade goods Performance and quality is poor.The quality and performance that can not meet the requirement Chinese Polystyrene product in market is poor, except foreign capitals and joint venture product, the product majority of domestic manufacturers can not meet the requirement of the users such as electron trade to product performance and quality, is difficult to enter this huge market.In electronics/electrical apparatus industry that polystyrene has the call, imported product has comparative advantage, and domestic resin only has a small amount of application, and can only be used for low grade products.Domestic well-known appliance manufacturers, in order to ensure its quality product, all uses the product of imported raw material or foreign capitals joint venture, and the polystyrene foamed be used in conjunction in shockproof outer packaging also uses the product of imported product or joint venture usually.Unit scale is less than normal, lacks competitiveness.Domestic at present have nearly 40 of polystyrene factory, and most of ability, below 30,000 tons/year, also has many scales at the packaged unit of about 10,000 tons/year.The factory that ability reaches 100,000 tons/year only has 5.Dingus not only quality product can not be compared with the large production equipment of advanced person, and production cost is also higher, is in a disadvantageous position in market competition.Starving, device working rate is low.The high speed development produced with polystyrene is incompatible, and its Materials Styrene production development is relatively slow, and the raw material sources of polystyrene devices are restricted, and working rate is affected.1999, Chinese production of styrene ability was 84.6 ten thousand tons/year, output 60.2 ten thousand tons, even if all also only can meet 43% of domestic polystyrene need of production for the production of polystyrene.The deficiency of raw material supply is the one of the main reasons causing device working rate lower.1999, Chinese Polystyrene output about 940,000 tons, the average working rate of device was only 67%, and throughput is left unused in a large number, further increases the degree of dependence of China to import polystyrene.And popularizing along with humanity concept, and the formation of novel harmonious society, design high medical PS antibacterial film of a kind of intestinal bacteria antibiotic rate, streptococcus aureus antibiotic rate, percent thermal shrinkage and elongation and preparation method thereof and be very important.

Summary of the invention

the technical problem solved:

The application, for above-mentioned technical problem, provides a kind of medical PS antibacterial film and preparation method thereof, solves the technical problems such as existing medical novel material intestinal bacteria antibiotic rate, streptococcus aureus antibiotic rate, percent thermal shrinkage and elongation are low.

technical scheme:

A kind of medical PS antibacterial film, the raw materials by weight portion proportioning of described medical PS antibacterial film is as follows: PS100 part; CPE10-30 part; Nanometer silver-zirconium phosphate antimicrobial 1-5 part; Nanometer LDPE5-25 part; Styrene-butadiene block copolymer 20-40 part; SEBS10-30 part; Surface treatment agent 1.5-5.5 part; LDPE20-40 part; Methylene dichloride 40-80 part; POE is 15-35 part; UV light absorber 0.1-0.5 part; N, N-diethylethanolamine is 1-3 part; Aluminum chloride 10-30 part; Zinic stearas is 2-8 part; Tetracol phenixin is 40-60 part.

As a preferred technical solution of the present invention: the raw materials by weight portion proportioning of described medical PS antibacterial film is as follows: PS100 part; CPE15-25 part; Nanometer silver-zirconium phosphate antimicrobial 2-4 part; Nanometer LDPE10-20 part; Styrene-butadiene block copolymer 25-35 part; SEBS15-25 part; Surface treatment agent 2.5-4.5 part; LDPE25-35 part; Methylene dichloride 50-70 part; POE is 20-30 part; UV light absorber 0.2-0.4 part; N, N-diethylethanolamine is 1.5-2.5 part; Aluminum chloride 15-25 part; Zinic stearas is 4-6 part; Tetracol phenixin is 45-55 part.

As a preferred technical solution of the present invention: the raw materials by weight portion proportioning of described medical PS antibacterial film is as follows: PS100 part; CPE20 part; Nanometer silver-zirconium phosphate antimicrobial 3 parts; Nanometer LDPE15 part; Styrene-butadiene block copolymer 30 parts; SEBS20 part; Surface treatment agent 3.5 parts; LDPE30 part; Methylene dichloride 60 parts; POE is 25 parts; UV light absorber 0.3 part; N, N-diethylethanolamine is 2 parts; Aluminum chloride 20 parts; Zinic stearas is 5 parts; Tetracol phenixin is 50 parts.

As a preferred technical solution of the present invention: described surface treatment agent adopts silane surface treatment agent or boric acid ester surface treatment agent.

As a preferred technical solution of the present invention: described UV light absorber adopts UV-P or ESCALOL 567.

As a preferred technical solution of the present invention: the preparation method of described medical PS antibacterial film, comprises the steps:

The first step: take PS, CPE, nanometer silver-zirconium phosphate antimicrobial, nanometer LDPE, styrene-butadiene block copolymer, SEBS, surface treatment agent, LDPE, dicumyl peroxide, POE, UV light absorber, N, N-diethylethanolamine, aluminum chloride, Zinic stearas and tetracol phenixin according to parts by weight proportioning;

Second step: PS, CPE, nanometer silver-zirconium phosphate antimicrobial, nanometer LDPE and POE are dropped in reactor and is heated to 65-85 DEG C, stir 20-40min, stirring velocity 400-600 rev/min;

3rd step: then add surplus stock, be warming up to 95-135 DEG C, stirs 10-30min, stirring velocity 600-1000 rev/min;

4th step: mixed material is dropped into extruding pelletization in twin screw extruder, barrel temperature 120 DEG C, 130 DEG C, 140 DEG C, 150 DEG C, 155 DEG C, 160 DEG C, 165 DEG C and 170 DEG C, screw speed 55-75 rev/min, rolling press rolling temperature 175-185 DEG C, expander temperature 150-170 DEG C, packs after batching.

beneficial effect:

One of the present invention medical PS antibacterial film and preparation method thereof adopts above technical scheme compared with prior art, has following technique effect: 1, product 0 DEG C of longitudinal tensile strain rate 5-45%, tensile strength 45-65MPa; 2, intestinal bacteria antibiotic rate 95.9-99.9%, streptococcus aureus antibiotic rate 97.5-99.5%; 3, longitudinal thermal contraction 25-45%, lateral shrinkage is 20-40%; 4, tear strength 10-12kN/m, the widespread production not division of history into periods can replace current material.

Embodiment

embodiment 1:

PS100 part is taken according to parts by weight proportioning; CPE10 part; Nanometer silver-zirconium phosphate antimicrobial 1 part; Nanometer LDPE5 part; Styrene-butadiene block copolymer 20 parts; SEBS10 part; Boric acid ester surface treatment agent 1.5 parts; LDPE20 part; Methylene dichloride 40 parts; POE is 15 parts; ESCALOL 567 0.1 part; N, N-diethylethanolamine is 1 part; Aluminum chloride 10 parts; Zinic stearas is 2 parts; Tetracol phenixin is 40 parts.

PS, CPE, nanometer silver-zirconium phosphate antimicrobial, nanometer LDPE and POE are dropped in reactor and be heated to 65 DEG C, stir 20min, stirring velocity 400 revs/min, then adds surplus stock, is warming up to 95 DEG C, stirs 10min, stirring velocity 600 revs/min.

Mixed material is dropped into extruding pelletization in twin screw extruder, barrel temperature 120 DEG C, 130 DEG C, 140 DEG C, 150 DEG C, 155 DEG C, 160 DEG C, 165 DEG C and 170 DEG C, screw speed 55 revs/min, rolling press rolling temperature 175 DEG C, expander temperature 150 DEG C, packs after batching.

Product 0 DEG C of longitudinal tensile strain rate 5%, tensile strength 45MPa; Intestinal bacteria antibiotic rate 95.9%, streptococcus aureus antibiotic rate 97.5%; Longitudinal thermal contraction 25%, lateral shrinkage is 20%; Tear strength 10kN/m.

embodiment 2:

PS100 part is taken according to parts by weight proportioning; CPE30 part; Nanometer silver-zirconium phosphate antimicrobial 5 parts; Nanometer LDPE25 part; Styrene-butadiene block copolymer 40 parts; SEBS30 part; Boric acid ester surface treatment agent 5.5 parts; LDPE40 part; Methylene dichloride 80 parts; POE is 35 parts; ESCALOL 567 0.5 part; N, N-diethylethanolamine is 3 parts; Aluminum chloride 30 parts; Zinic stearas is 8 parts; Tetracol phenixin is 60 parts.

PS, CPE, nanometer silver-zirconium phosphate antimicrobial, nanometer LDPE and POE are dropped in reactor and be heated to 85 DEG C, stir 40min, stirring velocity 600 revs/min, then adds surplus stock, is warming up to 135 DEG C, stirs 30min, stirring velocity 1000 revs/min.

Mixed material is dropped into extruding pelletization in twin screw extruder, barrel temperature 120 DEG C, 130 DEG C, 140 DEG C, 150 DEG C, 155 DEG C, 160 DEG C, 165 DEG C and 170 DEG C, screw speed 75 revs/min, rolling press rolling temperature 185 DEG C, expander temperature 170 DEG C, packs after batching.

Product 0 DEG C of longitudinal tensile strain rate 15%, tensile strength 50MPa; Intestinal bacteria antibiotic rate 96.9%, streptococcus aureus antibiotic rate 98%; Longitudinal thermal contraction 30%, lateral shrinkage is 25%; Tear strength 10.5kN/m.

embodiment 3:

PS100 part is taken according to parts by weight proportioning; CPE15 part; Nanometer silver-zirconium phosphate antimicrobial 2 parts; Nanometer LDPE10 part; Styrene-butadiene block copolymer 25 parts; SEBS15 part; Silane surface treatment agent 2.5 parts; LDPE25 part; Methylene dichloride 50 parts; POE is 20 parts; ESCALOL 567 0.2 part; N, N-diethylethanolamine is 1.5 parts; Aluminum chloride 15 parts; Zinic stearas is 4 parts; Tetracol phenixin is 45 parts.

PS, CPE, nanometer silver-zirconium phosphate antimicrobial, nanometer LDPE and POE are dropped in reactor and be heated to 70 DEG C, stir 25min, stirring velocity 450 revs/min, then adds surplus stock, is warming up to 105 DEG C, stirs 15min, stirring velocity 700 revs/min.

Mixed material is dropped into extruding pelletization in twin screw extruder, barrel temperature 120 DEG C, 130 DEG C, 140 DEG C, 150 DEG C, 155 DEG C, 160 DEG C, 165 DEG C and 170 DEG C, screw speed 55-75 rev/min, rolling press rolling temperature 177 DEG C, expander temperature 155 DEG C, packs after batching.

Product 0 DEG C of longitudinal tensile strain rate 25%, tensile strength 55MPa; Intestinal bacteria antibiotic rate 97.9%, streptococcus aureus antibiotic rate 98.5%; Longitudinal thermal contraction 35%, lateral shrinkage is 30%; Tear strength 11kN/m.

embodiment 4:

PS100 part is taken according to parts by weight proportioning; CPE25 part; Nanometer silver-zirconium phosphate antimicrobial 4 parts; Nanometer LDPE20 part; Styrene-butadiene block copolymer 35 parts; SEBS25 part; Silane surface treatment agent 4.5 parts; LDPE35 part; Methylene dichloride 70 parts; POE is 30 parts; UV-P0.4 part; N, N-diethylethanolamine is 2.5 parts; Aluminum chloride 25 parts; Zinic stearas is 6 parts; Tetracol phenixin is 55 parts.

PS, CPE, nanometer silver-zirconium phosphate antimicrobial, nanometer LDPE and POE are dropped in reactor and be heated to 80 DEG C, stir 35min, stirring velocity 550 revs/min, then adds surplus stock, is warming up to 125 DEG C, stirs 25min, stirring velocity 900 revs/min.

Mixed material is dropped into extruding pelletization in twin screw extruder, barrel temperature 120 DEG C, 130 DEG C, 140 DEG C, 150 DEG C, 155 DEG C, 160 DEG C, 165 DEG C and 170 DEG C, screw speed 70 revs/min, rolling press rolling temperature 183 DEG C, expander temperature 165 DEG C, packs after batching.

Product 0 DEG C of longitudinal tensile strain rate 35%, tensile strength 60MPa; Intestinal bacteria antibiotic rate 98.9%, streptococcus aureus antibiotic rate 99%; Longitudinal thermal contraction 40%, lateral shrinkage is 35%; Tear strength 11.5kN/m.

embodiment 5:

PS100 part is taken according to parts by weight proportioning; CPE20 part; Nanometer silver-zirconium phosphate antimicrobial 3 parts; Nanometer LDPE15 part; Styrene-butadiene block copolymer 30 parts; SEBS20 part; Silane surface treatment agent 3.5 parts; LDPE30 part; Methylene dichloride 60 parts; POE is 25 parts; UV-P0.3 part; N, N-diethylethanolamine is 2 parts; Aluminum chloride 20 parts; Zinic stearas is 5 parts; Tetracol phenixin is 50 parts.

PS, CPE, nanometer silver-zirconium phosphate antimicrobial, nanometer LDPE and POE are dropped in reactor and be heated to 75 DEG C, stir 30min, stirring velocity 500 revs/min, then adds surplus stock, is warming up to 115 DEG C, stirs 20min, stirring velocity 800 revs/min.

Mixed material is dropped into extruding pelletization in twin screw extruder, barrel temperature 120 DEG C, 130 DEG C, 140 DEG C, 150 DEG C, 155 DEG C, 160 DEG C, 165 DEG C and 170 DEG C, screw speed 65 revs/min, rolling press rolling temperature 180 DEG C, expander temperature 160 DEG C, packs after batching.

Product 0 DEG C of longitudinal tensile strain rate 45%, tensile strength 65MPa; Intestinal bacteria antibiotic rate 99.9%, streptococcus aureus antibiotic rate 99.5%; Longitudinal thermal contraction 45%, lateral shrinkage is 40%; Tear strength 12kN/m.

Composition all components in above embodiment all can business be bought.

Above-described embodiment is just for setting forth content of the present invention, instead of restriction, and any change therefore in the implication suitable with claims of the present invention and scope, all should think to be included in the scope of claims.

Claims (6)

1. a medical PS antibacterial film, is characterized in that the raw materials by weight portion proportioning of described medical PS antibacterial film is as follows: PS100 part; CPE10-30 part; Nanometer silver-zirconium phosphate antimicrobial 1-5 part; Nanometer LDPE5-25 part; Styrene-butadiene block copolymer 20-40 part; SEBS10-30 part; Surface treatment agent 1.5-5.5 part; LDPE20-40 part; Methylene dichloride 40-80 part; POE is 15-35 part; UV light absorber 0.1-0.5 part; N, N-diethylethanolamine is 1-3 part; Aluminum chloride 10-30 part; Zinic stearas is 2-8 part; Tetracol phenixin is 40-60 part.

2. the medical PS antibacterial film of one according to claim 1, is characterized in that described medical PS antibacterial film raw materials by weight portion proportioning is as follows: PS100 part; CPE15-25 part; Nanometer silver-zirconium phosphate antimicrobial 2-4 part; Nanometer LDPE10-20 part; Styrene-butadiene block copolymer 25-35 part; SEBS15-25 part; Surface treatment agent 2.5-4.5 part; LDPE25-35 part; Methylene dichloride 50-70 part; POE is 20-30 part; UV light absorber 0.2-0.4 part; N, N-diethylethanolamine is 1.5-2.5 part; Aluminum chloride 15-25 part; Zinic stearas is 4-6 part; Tetracol phenixin is 45-55 part.

3. the medical PS antibacterial film of one according to claim 1, is characterized in that the raw materials by weight portion proportioning of described medical PS antibacterial film is as follows: PS100 part; CPE20 part; Nanometer silver-zirconium phosphate antimicrobial 3 parts; Nanometer LDPE15 part; Styrene-butadiene block copolymer 30 parts; SEBS20 part; Surface treatment agent 3.5 parts; LDPE30 part; Methylene dichloride 60 parts; POE is 25 parts; UV light absorber 0.3 part; N, N-diethylethanolamine is 2 parts; Aluminum chloride 20 parts; Zinic stearas is 5 parts; Tetracol phenixin is 50 parts.

4. the medical PS antibacterial film of one according to claim 1, is characterized in that: described surface treatment agent adopts silane surface treatment agent or boric acid ester surface treatment agent.

5. the medical PS antibacterial film of one according to claim 1, is characterized in that: described UV light absorber adopts UV-P or ESCALOL 567.

6. a preparation method for medical PS antibacterial film described in claim 1, is characterized in that, comprise the steps:

The first step: take PS, CPE, nanometer silver-zirconium phosphate antimicrobial, nanometer LDPE, styrene-butadiene block copolymer, SEBS, surface treatment agent, LDPE, dicumyl peroxide, POE, UV light absorber, N, N-diethylethanolamine, aluminum chloride, Zinic stearas and tetracol phenixin according to parts by weight proportioning;

Second step: PS, CPE, nanometer silver-zirconium phosphate antimicrobial, nanometer LDPE and POE are dropped in reactor and is heated to 65-85 DEG C, stir 20-40min, stirring velocity 400-600 rev/min;

3rd step: then add surplus stock, be warming up to 95-135 DEG C, stirs 10-30min, stirring velocity 600-1000 rev/min;

4th step: mixed material is dropped into extruding pelletization in twin screw extruder, barrel temperature 120 DEG C, 130 DEG C, 140 DEG C, 150 DEG C, 155 DEG C, 160 DEG C, 165 DEG C and 170 DEG C, screw speed 55-75 rev/min, rolling press rolling temperature 175-185 DEG C, expander temperature 150-170 DEG C, packs after batching.