CN104383408A

CN104383408A - Special cream for bone spur proliferation

Info

Publication number: CN104383408A
Application number: CN201410726923.5A
Authority: CN
Inventors: 李满才; 文建军
Original assignee: JIAHE COUNTY JINSEN AGRICULTURAL SCIENCE AND TECHNOLOGY DEVELOPMENT Co Ltd
Current assignee: Wen Jianjun
Priority date: 2014-12-05
Filing date: 2014-12-05
Publication date: 2015-03-04
Anticipated expiration: 2034-12-05
Also published as: CN104383408B

Abstract

The invention relates to a special cream for bone spur proliferation. The special cream is subjected to screening optimization and clinic verification for a long period of time. The traditional Chinese medicines for strengthening muscles and bones and regulating internal secretion, such as radix achyranthis bidentatae and dried radix rehmanniae, are selected as monarch drugs in a prescription aiming at the source of bone spur proliferation; the traditional Chinese medicines for activating blood circulation to dissipate stasis, reducing swelling and relieving pain, such as shortleaf kyllinga herb and root of kongpo monkshood, are selected as ministerial drugs; the traditional Chinese medicines for promoting the circulation of qi, such as szechuan lovage rhizome and loosestrife, are selected as assistant drugs; and the reconciling traditional Chinese medicines, namely divaricate saposhnikovia root and nidus vespae are selected as conductant drugs. The special cream prepared according to a certain dosage is capable of strongly penetrating periosteum, decomposing and extracting bone toxins, simulating the skeleton to generate more lubricating fluid, repairing injured cartilage and periosteum, dissolving bone spurs, improving the bone tissue activity, exchanging an old bone into a new bone, and thoroughly curing the old bone spurs over the years; and the special cream is suitable for treatment of cervical spondylosis, protrusion of lumbar intervertebral disc and lumbar bone hyperplasia.

Description

Bony spur hypertrophy specially good effect cream

Technical field

The present invention relates to a kind of external used medicine for the treatment of hyperosteogeny and prolapse of lumbar intervertebral disc, hyperosteogeny of cervical vertebra, specifically a kind of bony spur hypertrophy specially good effect cream, the invention still further relates to the preparation method of this specially good effect cream.

Background technology

Bony spur hypertrophy belongs to " arthromyodynia " category of the traditional Chinese medical science, also known as " rheumatism involving the bone ".The traditional Chinese medical science thinks that primary disease is relevant with wound, strain, obstruction of collaterals by blood stasis, the damp that is affected by the cold, phlegm resistance, the caused by liver and kidney deficiency hyperosteogeny cause of disease etc.Understand by different subject and mainly contain: 1, pathology, irregular cartilage lesions, in Subchondral bone sclerosis, the cyst in heavy burden region, edge osteophytosis, the increase of metaphysis blood flow and synovitis in various degree.2, histology, early stage cartilage surface is cracked, the proliferation of chondrocytes, cartilage surface longitudinally split, crystallization deposition, there is repair of cartilage, osteophytosis simultaneously; There is the thorough destruction of cartilage late period, show as cartilage sclerosis, cartilage disappear and cartilage under focal osteonecrosis.3, biomechanics, the extensibility of articular cartilage, compressive resistance, anti-shearing force and cartilage permeability reduce.Cartilage moisture increases, excessive swelling, Subchondral bone sclerosis.4, biochemical change, the content of Dan Baiduotang proteoglycan PG or the decline of concentration, its molecular size and concentration class change, and synthesis and the degraded of the size of collagen fiber, arrangement and Matrix protein all occur abnormal change.5, threpsology, the basic reason of bony spur is calcium deficiency, is the result of stress response.Different for bony spur lesions position, the traditional Chinese medical science takes Chinese herb medicine, traction and massaging, acupuncture acupuncture, the external application of Chinese medicine, Chinese medicine fumigation and washing, naturopathy as the treatment of the method such as mineral bath, exercise therapy usually, and effect is different.Wherein oral Chinese medicine is due to comparatively large to the gastrointestinal irritability of people, and not easy for patients to accept, other therapies all exists the defect of curative effect instability.

On October 08th, 2003, Chinese invention patent application publication number CN1446558A discloses a kind of plaster for the treatment of rheumatic arthritis, and this plaster is made with the raw material of Chinese medicine of following consumption proportion and adjuvant: the Radix Aucklandiae; Radix Achyranthis Bidentatae; Rhizoma Chuanxiong; The Radix Rehmanniae; Herba Asari; The Radix Angelicae Dahuricae; Fructus Aurantii; Radix Gentianae Macrophyllae; Radix Angelicae Pubescentis; Radix Saposhnikoviae; Radix Angelicae Sinensis; Semen Hydnocarpi; Radix Scutellariae; Rhizoma Et Radix Notopterygii; Rhizoma Arisaematis; The Rhizoma Pinelliae; Radix Paeoniae Rubra; Bulbus Fritillariae Uninbracteatae; Semen Armeniacae Amarum; Semen Ricini; Rhizoma Atractylodis; Folium Artemisiae Argyi; Bai Huan; Radix Aconiti; Cortex Cinnamomi; Radix Dipsaci; Rhizoma Anemones Raddeanae; Fructus Forsythiae; Radix Glycyrrhizae; Rhizoma Ligustici; Flos Caryophylli; Pericarpium Citri Reticulatae Viride; Herba Pogostemonis; The Radix Linderae; Herba Schizonepetae; Lignum Sappan; Radix Scrophulariae; Bombyx Batryticatus; Semen Persicae; Semen Pittospori Glabrati; Flos Carthami; Fructus Gleditsiae Abnormalis; Radix Clematidis; Radix Sophorae Flavescentis; Flos Hierochloes adoratae; Wen Ha; Periostracum Cicadae; Radix Aconiti Kusnezoffii; Nidus Vespae; Carapax Trionycis; Scorpio; Flos Lonicerae; Herba Ephedrae; The Pseudobulbus Bletillae (Rhizoma Bletillae); Radix Et Rhizoma Rhei; Blue or green maple rattan; Scolopendra; Periostracum Serpentis; Squama Manis; Cortex Acanthopancis; True Lignum Dalbergiae Odoriferae; Rhizoma Drynariae; Fructus Xanthii; Colophonium; Oleum Sesami; Tao Dan; In prescription of the present invention, monarch drug selects the Chinese medicine of the remove rheumatism such as Radix Achyranthis Bidentatae, Radix Angelicae Pubescentis, Radix Gentianae Macrophyllae, Radix Clematidis; The Chinese medicine of the activating blood circulation to dissipate blood stasis such as Rhizoma Chuanxiong, Flos Carthami, Radix Paeoniae Rubra, Radix Scrophulariae selected by ministerial drug; The circulation of qi promoting class Chinese medicines such as the Radix Aucklandiae, Folium Artemisiae Argyi, Pericarpium Citri Reticulatae Viride, Flos Lonicerae selected by adjuvant drug; Medicine is made to select the mediation class Chinese medicines such as Radix Glycyrrhizae; Colophonium, Oleum Sesami, Tao Danwei cream adjuvant.This plaster is applicable to the treatment of the arthritis such as gonarthritis, anconitis, scapulohumeral periarthritis, sciatica and rheumatic arthritis through clinical trial, but not remarkable for hyperosteogeny curative effects such as cervical spondylosis, prolapse of lumbar intervertebral disc, lumbar vertebra hyperosteogeny, knee joint hyperosteogenys.

Summary of the invention

For effectively overcoming the defect of above-mentioned Therapeutic Method, the present invention is on the basis of summing up forefathers' experience, through drug screening chronically, prescription optimization and thousands of routine clinical verification, propose a kind of specially for the bony spur hypertrophy specially good effect cream that hyperosteogeny and prolapse of lumbar intervertebral disc, cervical spine bone hyperplasia are evident in efficacy.

The technical solution adopted for the present invention to solve the technical problems is: a kind of bony spur hypertrophy specially good effect cream, adds adjuvant with the raw material of Chinese medicine of following masses proportioning and make mastic:

The Radix Aucklandiae 1.6%, Radix Achyranthis Bidentatae 1.6%, Rhizoma Chuanxiong 1.6%, the Radix Rehmanniae 1.6%, Herba Asari 1.6%, the Radix Angelicae Dahuricae 1.6%, Fructus Aurantii 1.6%, Radix Gentianae Macrophyllae 1.6%, Radix Angelicae Pubescentis 1.6%, Radix Saposhnikoviae 1.6%, Radix Angelicae Sinensis 1.6%, Semen Hydnocarpi 1.6%, Radix Scutellariae 1.6%, Rhizoma Et Radix Notopterygii 1.6%, Rhizoma Arisaematis 1.6%, the Rhizoma Pinelliae 1.6%, Radix Paeoniae Rubra 1.6%, Bulbus Fritillariae Uninbracteatae 1.6%, Semen Armeniacae Amarum 1.6%, Semen Ricini 1.6%, the Rhizoma Atractylodis Macrocephalae 1.6%, Rhizoma Atractylodis 1.6%, Folium Artemisiae Argyi 1.6%, Radix Aconiti 1.6%, Cortex Cinnamomi 1.6%, Rhizoma Alpiniae Officinarum 1.6%, Radix Dipsaci 1.6%, Rhizoma Anemones Raddeanae 1.6%, Fructus Forsythiae 1.6%, Radix Glycyrrhizae uralensis 1.6%, western rhizome of chuanxiong 1.6%, Flos Caryophylli 1.6%, Pericarpium Citri Reticulatae Viride 1.6%, Herba Pogostemonis 1.6%, the Radix Linderae 1.6%, Herba Schizonepetae 1.6%, Lignum Sappan 1.6%, Radix Scrophulariae 1.6%, Bombyx Batryticatus 1.6%, Semen Persicae 1.6%, SHANZHIZI 1.6%, Flos Carthami 1.6%, Fructus Gleditsiae Abnormalis 1.6%, Radix Clematidis 1.6%, Radix Sophorae Flavescentis 1.6%, literary composition breathes out 1.6%, Periostracum Cicadae 1.6%, Radix Aconiti Kusnezoffii 1.6%, Nidus Vespae 1.6%, Carapax Trionycis 1.6%, Scorpio 1.6%, Flos Lonicerae 1.6%, Herba Ephedrae 1.6%, the Pseudobulbus Bletillae (Rhizoma Bletillae) 1.6%, Radix Et Rhizoma Rhei 1.6%, blue or green maple rattan 1.6%, Scolopendra 1.2%, Squama Manis 0.8%, bitter refining skin 0.8%, Cortex Acanthopancis 0.8%, true Lignum Dalbergiae Odoriferae 0.8%, Rhizoma Drynariae 0.8%, Fructus Xanthii 0.8%, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 0.8%, Herba Kyllingae 0.8%, Radix aconiti kongboensis 0.8%, Semen Strychni 0.8%, Periostracum Serpentis 1.2%, Cortex Ulmi Parvifoliae 0.8%,

Be sheet medical material by above-mentioned each component slices, soak with Oleum Sesami; The soak time of Oleum Sesami, summer is 3 days, and spring is 5 days, and autumn is 5 days, and winter is 10 days, and Oleum Sesami consumption is 2-3 times of raw material of Chinese medicine gross mass; After immersion completes, by soaked medical material with soak Oleum Sesami together intense fire heat; Slowly heat, until medical material is dark brown when using slow fire instead after the boiling of immersion Oleum Sesami; The medicine taking advantage of hot moulding to get in filter bag and gauze bag medical material is oily, waste; With slow fire refining medicine oil to dripping into pearl, slowly adding Colophonium, continue stirring and heat under stirring, until white cigarette becomes blue or green cigarette, the addition of Colophonium is 0.1-0.12 times of raw material of Chinese medicine gross mass; Now medicine oil is in Gold production paste, and pull mastic becomes filament length 100mm continuous; Get mastic and make plaster.

In prescription of the present invention, monarch drug selects Radix Achyranthis Bidentatae, the Radix Rehmanniae, Radix Gentianae Macrophyllae, Semen Hydnocarpi, Radix Dipsaci, Radix Sophorae Flavescentis, the bone and muscle strengthening such as Periostracum Cicadae, Scorpio, true Lignum Dalbergiae Odoriferae, Rhizoma Drynariae, the Chinese medicine of endocrine regulation; The Chinese medicine of the activating blood circulation to dissipate blood stasis such as Herba Asari, the Radix Angelicae Dahuricae, Radix Angelicae Pubescentis, Rhizoma Arisaematis, the Rhizoma Pinelliae, Rhizoma Chuanxiong, Flos Carthami, Radix Paeoniae Rubra, Radix Scrophulariae, Semen Ricini, Radix Aconiti, Cortex Cinnamomi, Rhizoma Alpiniae Officinarum, Fructus Forsythiae, Radix Glycyrrhizae uralensis, Lignum Sappan, Bombyx Batryticatus, Semen Persicae, SHANZHIZI, Fructus Gleditsiae Abnormalis, Radix Clematidis, Radix Aconiti Kusnezoffii, Carapax Trionycis, Herba Ephedrae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Et Rhizoma Rhei, blue or green maple rattan, Scolopendra, Squama Manis, Herba Kyllingae, Radix aconiti kongboensis, Semen Strychni, Periostracum Serpentis, Cortex Ulmi Parvifoliae, detumescence and pain relieving selected by ministerial drug; Adjuvant drug selects circulation of qi promoting, the cold removing such as the Radix Aucklandiae, Fructus Aurantii, Radix Scutellariae, Rhizoma Et Radix Notopterygii, Bulbus Fritillariae Uninbracteatae, Folium Artemisiae Argyi, Pericarpium Citri Reticulatae Viride, Flos Lonicerae, the Rhizoma Atractylodis Macrocephalae, Rhizoma Atractylodis, Rhizoma Anemones Raddeanae, western rhizome of chuanxiong, Flos Caryophylli, Herba Pogostemonis, the Radix Linderae, Herba Schizonepetae, bitter refining skin, Cortex Acanthopancis, Fructus Xanthii, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) to wet and sharp joint type Chinese medicine; Medicine is made to select the mediation class Chinese medicines such as Radix Saposhnikoviae, Nidus Vespae, literary composition Kazakhstan; Colophonium, Oleum Sesami are cream adjuvant processed.Compared with the prior art, the present invention does not use white joyous, Rhizoma Ligustici, Radix Glycyrrhizae, Flos Hierochloes adoratae and Tao Dan; Prescription of the present invention uses meridian tropism principle, use medicine coordinate mutually into usefulness, the large compound recipe of composition multi-flavor medicine, to play the good result of medicine.Prescription of the present invention adds ministerial drug Rhizoma Alpiniae Officinarum, Radix Glycyrrhizae uralensis, Herba Kyllingae, Radix aconiti kongboensis, Cortex Ulmi Parvifoliae; The increase of these components, can make the endocrine regulation effective ingredient in monarch drug change, and creates and stimulates medullary cell hemopoietic, improves the function treating bone self-healing ability.Prescription of the present invention also add the adjuvant drug Rhizoma Atractylodis Macrocephalae, western rhizome of chuanxiong, bitter refining skin and Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis), the bone and muscle strengthening composition in monarch drug can be assisted to penetrate into skeleton smoothly, and strengthen nutrition and the regeneration capacity of skeleton, what make pathological changes organizes work again, reach the molten bony spur that disappears, the effect of dredging bone marrow core.Make medicine Radix Saposhnikoviae, Nidus Vespae, the literary composition of prescription of the present invention are breathed out and are used hail water treatment separately, and collection natural essence China, lead group medicine, the capable stagnant through sick institute of relieving accumulation of pathogens, creates the technique effect of hypersynchronous.

Therefore, the present invention can penetrate skin and produce antiinflammatory, and pain relieving, activating blood circulation to dissipate blood stasis, stimulate the menstrual flow away network, effects such as deep, expelling wind and cold of having one's ideas straightened out.Plaster stimulates the synovial fluid produced between bone and bone, and nutrition cartilage surface reduces the friction between bone, strengthens nutrition and the regeneration capacity of skeleton; Composition hypersynchronous, stimulates medullary cell hemopoietic, improves and treats bone self-healing ability, pathological changes organize work again, disappear molten bony spur, dredging bone marrow core.A course for the treatment of of the lighter, 3 to 4 courses for the treatment of of severe one, just can cure.Add up from more than 120 cases, cure rate of the present invention reaches more than 90%.

The effect that the present invention possesses and advantage are: effective ingredient brute force of the present invention penetrates periosteum, sclerotin, bone marrow, toxin is decomposed and pulls out; Plaster stimulates the synovial fluid produced between bone and bone, and nutrition cartilage surface reduces the friction between bone, strengthens nutrition and the regeneration capacity of skeleton; Composition hypersynchronous, stimulates medullary cell hemopoietic, improves and treats bone self-healing ability, pathological changes organize work again, disappear molten bony spur, dredging bone marrow core.Mastic of the present invention can make plaster, easy to use, stable curative effect, and thorough treatment is without any side effects.

Detailed description of the invention

Following examples further illustrate of the present invention, instead of limitation of the present invention.

The present embodiment treatment burn and scald medicine and method, the medicine used is made up of the component of following weight:

Radix Aucklandiae 16g, Radix Achyranthis Bidentatae 16g, Rhizoma Chuanxiong 16g, Radix Rehmanniae 16g, Herba Asari 16g, Radix Angelicae Dahuricae 16g, Fructus Aurantii 16g, Radix Gentianae Macrophyllae 16g, Radix Angelicae Pubescentis 16g, Radix Saposhnikoviae 16g, Radix Angelicae Sinensis 16g, Semen Hydnocarpi 16g, Radix Scutellariae 16g, Rhizoma Et Radix Notopterygii 16g, Rhizoma Arisaematis 16g, Rhizoma Pinelliae 16g, Radix Paeoniae Rubra 16g, Bulbus Fritillariae Uninbracteatae 16g, Semen Armeniacae Amarum 16g, Semen Ricini 16g, Rhizoma Atractylodis Macrocephalae 16g, Rhizoma Atractylodis 16g, Folium Artemisiae Argyi 16g, Radix Aconiti 16g, Cortex Cinnamomi 16g, Rhizoma Alpiniae Officinarum 16g, Radix Dipsaci 16g, Rhizoma Anemones Raddeanae 16g, Fructus Forsythiae 16g, Radix Glycyrrhizae uralensis 16g, western rhizome of chuanxiong 16g, Flos Caryophylli 16g, Pericarpium Citri Reticulatae Viride 16g, Herba Pogostemonis 16g, Radix Linderae 16g, Herba Schizonepetae 16g, Lignum Sappan 16g, Radix Scrophulariae 16g, Bombyx Batryticatus 16g, Semen Persicae 16g, SHANZHIZI 16g, Flos Carthami 16g, Fructus Gleditsiae Abnormalis 16g, Radix Clematidis 16g, Radix Sophorae Flavescentis 16g, 16g breathed out in literary composition, Periostracum Cicadae 16g, Radix Aconiti Kusnezoffii 16g, Nidus Vespae 16g, Carapax Trionycis 16g, Scorpio 16g, Flos Lonicerae 16g, Herba Ephedrae 16g, Pseudobulbus Bletillae (Rhizoma Bletillae) 16g, Radix Et Rhizoma Rhei 16g, blue or green maple rattan 16g, Scolopendra 12g, Squama Manis 8g, bitter refining skin 8g, Cortex Acanthopancis 8g, true Lignum Dalbergiae Odoriferae 8g, Rhizoma Drynariae 8g, Fructus Xanthii 8g, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 8g, Herba Kyllingae 8g, Radix aconiti kongboensis 8g, Semen Strychni 8g, Periostracum Serpentis 12g, Cortex Ulmi Parvifoliae 8g,

Be sheet medical material by above-mentioned each component slices, first that Radix Saposhnikoviae, Nidus Vespae, Wen Hasan taste medical material hail blister is soft, then pick Bombyx Batryticatus, Periostracum Cicadae, Carapax Trionycis, Scorpio, Scolopendra, Squama Manis, the Radix Saposhnikoviae of Periostracum Serpentis and above-mentioned maceration, Nidus Vespae, literary composition breathe out mixing and fill same gauze bag; All the other sheet medical materials and gauze bag one are reinstated Oleum Sesami and are soaked; The soak time of Oleum Sesami, summer is 3 days, and spring is 5 days, and autumn is 5 days, and winter is 10 days, and Oleum Sesami consumption is the 2000g of raw material of Chinese medicine gross mass; After immersion completes, by soaked tablet of medical material and gauze bag and immersion Oleum Sesami together intense fire heat; Slowly heat when using slow fire instead after the boiling of immersion Oleum Sesami, and constantly roll sheet medical material and gauze bag, until sheet medical material is dark brown; Pulling sheet medical material out is placed in filter bag; The medicine taking advantage of hot moulding to get in filter bag and gauze bag medical material is oily, mixing medicine oil, waste; With slow fire refining medicine oil to dripping into pearl, slowly add Colophonium under stirring, continue stirring and heat, until white cigarette becomes blue or green cigarette, the addition of Colophonium is the 110g of raw material of Chinese medicine gross mass; Now medicine oil is in Gold production paste, and pull mastic becomes filament length 100mm continuous; Get mastic and make plaster.

During use, plaster of the present invention is affixed on outside, affected part, within every 3-5 days, changes once, according to state of an illness weight, continuous use 10-30 days.

Clinical practice of the present invention is summarized as follows:

The routine patient of clinical Stochastic choice 50: male patient 30 example, wherein lumbar intervertebral disc hyperosteogeny patient 15 example, patients with lumbar disc herniation 10 example, hyperosteogeny of cervical vertebra 5 example; Female patient 20 example, wherein lumbar intervertebral disc hyperosteogeny patient 10 example, patients with lumbar disc herniation 5 example, hyperosteogeny of cervical vertebra 5 example.

Clinical criteria: lumbar intervertebral disc hyperosteogeny patient waist local pain or ache, send out cool, movable time pain increase the weight of, some local are red and swollen, and lab testing Hemolytic streptococcus is positive; Patients with lumbar disc herniation pain in the lumbar region, the soreness of waist, sometimes cause two numbnesss of lower limbs, the Anular disruption around the visible spinal column of X-ray examination, Nucleus pulposus; Hyperosteogeny of cervical vertebra patient local pain, active receiving limit.

Therapeutic process: plaster of the present invention is affixed on outside, affected part, changes once for every 3-5 days, to lumbar intervertebral disc hyperosteogeny patient, and medication 10-20 days; To patients with lumbar disc herniation, medication 20-30 days.To hyperosteogeny of cervical vertebra patient, medication 10-15 days;

Outcome measure: " healing " refers to through treatment, patient surface's symptom (as pain, active receiving restriction, redness etc.) disappears, and lab testing Hemolytic streptococcus is negative; " effectively " refers to that patient surface's transference cure, lab testing Hemolytic streptococcus is negative through treatment.

Therapeutic effect: hyperosteogeny of cervical vertebra patient is after use one anticipatory remark invention plaster, and namely surface symptoms fades away; Patients with lumbar disc herniation and lumbar intervertebral disc hyperosteogeny patient are after use two anticipatory remark invention plaster, and namely surface symptoms fades away, and cure rate is 90%.

Model case 1: Mr. Li, man, 45 years old, conscious head left-right rotation is limited, and arm string pain; Go examination in hospital to be diagnosed as flu to fall neck, accept hospital transfusion to treat and do not take effect for more than 3 day, after be diagnosed as cervical spondylosis by hospital again, within more than 10 day, do not take effect at hospital's traction therapeutic again, so go to certain acupuncture therapy clinic voluntarily to see the doctor for treatment, treat do not take effect for more than 20 day by acupuncture, massage, cup, health promoting pillow.Finally forward here to see the doctor for treatment, be used alone plaster local and treat, inform after 3 days that symptom has alleviated and much almost disappear, no more side effects continues treatment of forcing on, and within 15 days, accuses more, after treatment 10 days again.Follow up a case by regular visits to and have no a recurrence in.Can conclude that the curative effect of plaster is higher than other therapies thus.

Model case 2: Mrs Tang, age: 62 years old, retired professor, suffers from prolapse of lumbar intervertebral disc 2 years, bad during fashion, specifically because the overworked state of an illness is aggravated, dare not lower limb be stepped on foot, go to bed and dare not stand up, treat and have no an improvement in month just entering clinic acupuncture, massage, come here upon somebody's introduction and force on.Therapeutic outcome is: after 3 days, further consultation says it is much betterly dared to walk, not getting a lift of coming of oneself walking 2 li during further consultation after 10 days, has used two to force on to feel symptom to eliminate completely, and after half a year, meeting has no recurrence.

Claims

1. a bony spur hypertrophy specially good effect cream, is characterized in that: add adjuvant with the raw material of Chinese medicine of following masses proportioning and make mastic: