CN104383286A - Paste for treating burns and scalds and preparation method of paste - Google Patents
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- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
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- A61K35/56—Materials from animals other than mammals
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- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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Abstract
The invention discloses a paste for treating burns and scalds and a preparation method of the paste. The paste is prepared from the following components in parts by weight: 0.5-2 parts of peltate yam rhizome extract, 15 parts of common bletilla tuber extract, 15 parts of angelica root extract, 2.5 parts of safflower extract, 5 parts of cape jasmine extract, 2-6 parts of berberine hydrochloride, 10 parts of borneol, 1 part of quick lime, 160 parts of tea oil and 160 parts of beewax. The preparation method of the paste comprises the following steps: firstly, according to the parts by weight of the components, heating the tea oil, and adding the beewax to the heated tea oil so that the beewax is melted in the tea oil; secondly, blending the quick lime with water to obtain lime milk; thirdly, while heating with slow fire and stirring at a low speed, orderly and slowly adding the berberine hydrochloride, the common bletilla tuber extract, the angelica root extract, the safflower extract, the cape jasmine extract, the Peltate Yam Rhizome extract, the borneol and the lime milk to the obtained tea oil-beewax solution, further stirring for 30 minutes after the medicinal materials are completely added, and then cooling until the temperature reaches a room temperature, thereby obtaining the paste for treating burns and scalds. The paste has remarkable effects of quickly pain stopping, anti-inflammation and anti-infection, tissue regeneration promoting, and the like, and is high in recovery speed, and no scars are left after the burns and the scalds are cured.
Description
Technical field
The invention belongs to medical art, be specifically related to a kind of unguentum for the treatment of empyrosis and preparation method thereof.
Background technology
Burn and scald are all the damages that human body is caused by corrosive substance, radiant heat source etc. such as flame, high temperature material, strong acid-bases, its degree of injury is different to the length of the action time of body with these source of damage, but all human body is damaged, have a strong impact on the orthobiosis of people.The existing medicine of much treating burn, scalding at present, but treatment speed is slow, price is high problem that these medicine ubiquities, very large financial burden is caused to injured medication person, and although the medicine had allows wound healing, but leave cicatrix after treatment, leave serious shade again to wounded body's body and mind.
Summary of the invention
An object of the present invention is unguentum that provide a kind of healing rate fast, cheap, that be applicable to treat III degree empyrosis.This ointment is applicable to below III degree and III degree various burn, scald, the various wounds such as chemical burn, gunpowder burns and boiled water burn.This ointment has the remarkable results such as pain relieving is rapid, antiinflammatory infection, granulation promoting, and recovery from illness speed is fast, and preventing from scar after recovery from illness.
The unguentum for the treatment of empyrosis of the present invention, comprise the component of following content: the Rhizoma Dioscoreae Zingiberensis extract of 0.5-2 weight portion, the bletilla striata extract of 15 weight portions, the Radix Angelicae Dahuricae extract of 15 weight portions, the Flos Carthami extract of 2.5 weight portions, the Fructus Gardeniae extract of 5 weight portions, the berberine hydrochloride of 2-6 weight portion, the Borneolum Syntheticum of 10 weight portions, the quicklime of 1 weight portion, the Oleum Camelliae of 160 weight portions, the Cera Flava of 160 weight portions.
Two of object of the present invention is the preparation method of the unguentum providing above-mentioned treatment empyrosis, and the method comprises the steps:
(1) Oleum Camelliae of 160 weight portions is heated, the Cera Flava of 160 weight portions is added wherein, makes Cera Flava be melted in Oleum Camelliae;
(2) by the quicklime of 1 weight portion suitable quantity of water furnishing lime cream;
(3) with under the heating of slow fire limit, limit low rate mixing, successively the lime cream that the Rhizoma Dioscoreae Zingiberensis extract of the Fructus Gardeniae extract of the Flos Carthami extract of the Radix Angelicae Dahuricae extract of the bletilla striata extract of the berberine hydrochloride of 2-6 weight portion, 15 weight portions, 15 weight portions, 2.5 weight portions, 5 weight portions, 0.5-2 weight portion, the Borneolum Syntheticum of 10 weight portions and step (2) are obtained is slowly joined in the obtained Oleum Camelliae-Cera Flava liquid of step (1), after medicine adds, stir 30min again, then dry in the air to room temperature, obtain product.
The pharmacological property of each component of the present invention is as follows:
Rhizoma Dioscoreae Zingiberensis extract is dioscin system mixture, has pain relieving, detumescence, antiinflammatory, analgesia, antibacterial, the effect such as antitumor and granulation promoting.Clinically with among the people be commonly used to treatment lung-heat, cough, damp and hot, drench pain, carbuncle, malignant boil, traumatic injury, sprain, mosquito bites and rheumatism etc.
The Pseudobulbus Bletillae (Rhizoma Bletillae) has effect of astringing to arrest bleeding, detumescence and promoting granulation, anti-inflammation, pain relieving; The Radix Angelicae Dahuricae has effect of dredging collateral, detumescence and apocenosis, granulation promoting, removing the necrotic tissue, anti-inflammatory analgetic; Flos Carthami has effect of promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain; Fructus Gardeniae has effect of calmness, hemostasis, heat-clearing and toxic substances removing, acceleration wound healing.They are all be used for the treatment of the parts of generic medicinal plants burning wound.
Berberine is extract from the Chinese crude drug such as Rhizoma Coptidis, Radix Berberidis, a kind of broad spectrum antimicrobicide, and to multiple pathogenic bacteria as Hemolytic streptococcus, staphylococcus aureus etc. have strong inhibitory action.In addition, berberine also has calm, analgesic activity.
Borneolum Syntheticum is mainly containing Borneolum Syntheticum (59.78% ~ 58.93%), isoborneol (38.98% ~ 37.52%) and Camphora (2.70% ~ 2.09%), and it has antibacterial, antiinflammatory action.Meanwhile, Borneolum Syntheticum can make skin produce refrigerant sense, eliminates causalgia sense.
Quicklime, after water-soluble, with Ca (OH)
2form exists, and calcium ion has astriction, has and promotes incrustation and wound healing; Meanwhile, Ca (OH)
2alkalescence, can in and the fatty acid of Oleum Camelliae Emulsion hydrolysis, regulate the pH effect of medicinal liquid.
Containing flavone and abundant natural Vitamin E in Oleum Camelliae, there is fine moisturizing, antiinflammatory, antibacterial, analgesic effect.
The using method of unguentum of the present invention is, by paste application in affected part.
Of the present invention have following features:
(1) the present invention's Chinese medicine material used is its abstract, and effective ingredient concentration is high, more easily play curative effect.
(2) the present invention uses Chinese medicine extract, is easy to quality standard and formulates and control of product quality.
(3) the invention provides ointment for treating burn and scald, be applicable to various burn, scald, pain relieving is rapid, the Be very effective such as antiinflammatory infection, granulation promoting, and recovery from illness speed is fast, and preventing from scar after recovery from illness.
(4) ointment for treating burn and scald cost of the present invention is low, price is low, and preparation is simple, scalds burn medicine for common people provide the external that a kind of house is standing, price is suitable, effective.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is made a more detailed description.Described each component raw material commercially all has off-the-shelf to sell, and device therefor is also conventional equipment.
Embodiment 1:
Component and the content of the agent of the present embodiment ointment are: 0.5g Rhizoma Dioscoreae Zingiberensis extract, 15g bletilla striata extract, 15g Radix Angelicae Dahuricae extract, 2.5g Flos Carthami extract, 5g Fructus Gardeniae extract, 6g berberine hydrochloride, 10g Borneolum Syntheticum, 1g quicklime, 160g Oleum Camelliae, 160g Cera Flava.
The preparation process of the present embodiment ointment agent is as follows:
Step one, get Oleum Camelliae 160g and heat, 160g Cera Flava is added wherein, Cera Flava is melted in Oleum Camelliae.
Step 2, by 1g quicklime suitable quantity of water furnishing lime cream.
3rd step, with the heating of slow fire limit, under the low rate mixing of limit, successively the quicklime of 6g berberine hydrochloride, 15g bletilla striata extract, 15g Radix Angelicae Dahuricae extract, 2.5g Flos Carthami extract, 5g Fructus Gardeniae extract, 0.5g Rhizoma Dioscoreae Zingiberensis extract, 10g Borneolum Syntheticum and step 2 breast is slowly joined in the Oleum Camelliae-Cera Flava liquid of step one, after medicine adds, stir 30min again, then dry in the air to room temperature, namely complete the preparation of burn and scald ointment.
Embodiment 2:
Component and the content of the burn and scald drug unguentum of the present embodiment are: 1.0g Rhizoma Dioscoreae Zingiberensis extract, 15g bletilla striata extract, 15g Radix Angelicae Dahuricae extract, 2.5g Flos Carthami extract, 5g Fructus Gardeniae extract, 4g berberine hydrochloride, 10g Borneolum Syntheticum, 1g quicklime, 160g Oleum Camelliae, 160g Cera Flava.
The preparation process sequence of the burn and scald drug unguentum of the present embodiment is as follows:
Step one, get Oleum Camelliae 160g and heat, 160g Cera Flava is added wherein, Cera Flava is melted in Oleum Camelliae.
Step 2, by 1g quicklime suitable quantity of water furnishing lime cream.
3rd step, with the heating of slow fire limit, under the low rate mixing of limit, successively the quicklime of 4g berberine hydrochloride, 15g bletilla striata extract, 15g Radix Angelicae Dahuricae extract, 2.5g Flos Carthami extract, 5g Fructus Gardeniae extract, 1.0g Rhizoma Dioscoreae Zingiberensis extract, 10g Borneolum Syntheticum and step 2 breast is slowly joined in the Oleum Camelliae-Cera Flava liquid of step one, after medicine adds, stir 30min again, then dry in the air to room temperature, namely complete the preparation of burn and scald ointment.
Embodiment 3:
Component and the content of the burn and scald drug unguentum of the present embodiment are: 1.5g Rhizoma Dioscoreae Zingiberensis extract, 15g bletilla striata extract, 15g Radix Angelicae Dahuricae extract, 2.5g Flos Carthami extract, 5g Fructus Gardeniae extract, 4g berberine hydrochloride, 10g Borneolum Syntheticum, 1g quicklime, 160g Oleum Camelliae, 160g Cera Flava.
The preparation process sequence of the burn and scald drug unguentum of the present embodiment is as follows:
Step one, get Oleum Camelliae 160g and heat, 160g Cera Flava is added wherein, Cera Flava is melted in Oleum Camelliae.
Step 2, by 1g quicklime suitable quantity of water furnishing lime cream.
3rd step, with the heating of slow fire limit, under the low rate mixing of limit, successively the quicklime of 4g berberine hydrochloride, 15g bletilla striata extract, 15g Radix Angelicae Dahuricae extract, 2.5g Flos Carthami extract, 5g Fructus Gardeniae extract, 1.5g Rhizoma Dioscoreae Zingiberensis extract, 10g Borneolum Syntheticum and step 2 breast is slowly joined in the Oleum Camelliae-Cera Flava liquid of step one, after medicine adds, stir 30min again, then dry in the air to room temperature, namely complete the preparation of burn and scald ointment.
Embodiment 4:
Component and the content of the burn and scald drug unguentum of the present embodiment are: 2g Rhizoma Dioscoreae Zingiberensis extract, 15g bletilla striata extract, 15g Radix Angelicae Dahuricae extract, 2.5g Flos Carthami extract, 5g Fructus Gardeniae extract, 2g berberine hydrochloride, 10g Borneolum Syntheticum, 1g quicklime, 160g Oleum Camelliae, 160g Cera Flava.
The preparation process sequence of the burn and scald drug unguentum of the present embodiment is as follows:
Step one, get Oleum Camelliae 160g and heat, 160g Cera Flava is added wherein, Cera Flava is melted in Oleum Camelliae.
Step 2, by 1g quicklime suitable quantity of water furnishing lime cream.
3rd step, with the heating of slow fire limit, under the low rate mixing of limit, successively the quicklime of 2g berberine hydrochloride, 15g bletilla striata extract, 15g Radix Angelicae Dahuricae extract, 2.5g Flos Carthami extract, 5g Fructus Gardeniae extract, 2g Rhizoma Dioscoreae Zingiberensis extract, 10g Borneolum Syntheticum and step 2 breast is slowly joined in the Oleum Camelliae-Cera Flava liquid of step one, after medicine adds, stir 30min again, then dry in the air to room temperature, namely complete the preparation of burn and scald ointment.
Embodiment 5:
Component and the content of the burn and scald drug unguentum of the present embodiment are: 2g Rhizoma Dioscoreae Zingiberensis extract, 15g bletilla striata extract, 15g Radix Angelicae Dahuricae extract, 2.5g Flos Carthami extract, 5g Fructus Gardeniae extract, 6g berberine hydrochloride, 10g Borneolum Syntheticum, 1g quicklime, 160g Oleum Camelliae, 160g Cera Flava.
The preparation process sequence of the burn and scald drug unguentum of the present embodiment is as follows:
Step one, get Oleum Camelliae 160g and heat, 160g Cera Flava is added wherein, Cera Flava is melted in Oleum Camelliae.
Step 2, by 1g quicklime suitable quantity of water furnishing lime cream.
3rd step, with the heating of slow fire limit, under the low rate mixing of limit, successively the quicklime of 6g berberine hydrochloride, 15g bletilla striata extract, 15g Radix Angelicae Dahuricae extract, 2.5g Flos Carthami extract, 5g Fructus Gardeniae extract, 2g Rhizoma Dioscoreae Zingiberensis extract, 10g Borneolum Syntheticum and step 2 breast is slowly joined in the Oleum Camelliae-Cera Flava liquid of step one, after medicine adds, stir 30min again, then dry in the air to room temperature, namely complete the preparation of burn and scald ointment.
Embodiment 6:
Component and the content of the burn and scald drug unguentum of the present embodiment are: 0.5g Rhizoma Dioscoreae Zingiberensis extract, 15g bletilla striata extract, 15g Radix Angelicae Dahuricae extract, 2.5g Flos Carthami extract, 5g Fructus Gardeniae extract, 2g berberine hydrochloride, 10g Borneolum Syntheticum, 1g quicklime, 160g Oleum Camelliae, 160g Cera Flava.
The preparation process sequence of the burn and scald drug unguentum of the present embodiment is as follows:
Step one, get Oleum Camelliae 160g and heat, 160g Cera Flava is added wherein, Cera Flava is melted in Oleum Camelliae.
Step 2, by 1g quicklime suitable quantity of water furnishing lime cream.
3rd step, with the heating of slow fire limit, under the low rate mixing of limit, successively the quicklime of 2g berberine hydrochloride, 15g bletilla striata extract, 15g Radix Angelicae Dahuricae extract, 2.5g Flos Carthami extract, 5g Fructus Gardeniae extract, 0.5g Rhizoma Dioscoreae Zingiberensis extract, 10g Borneolum Syntheticum and step 2 breast is slowly joined in the Oleum Camelliae-Cera Flava liquid of step one, after medicine adds, stir 30min again, then dry in the air to room temperature, namely complete the preparation of burn and scald ointment.
Embodiment 7:
Component and the content of the burn and scald drug unguentum of the present embodiment are: 1.25g Rhizoma Dioscoreae Zingiberensis extract, 15g bletilla striata extract, 15g Radix Angelicae Dahuricae extract, 2.5g Flos Carthami extract, 5g Fructus Gardeniae extract, 4g berberine hydrochloride, 10g Borneolum Syntheticum, 1g quicklime, 160g Oleum Camelliae, 160g Cera Flava.
The preparation process sequence of the burn and scald drug unguentum of the present embodiment is as follows:
Step one, get Oleum Camelliae 160g and heat, 160g Cera Flava is added wherein, Cera Flava is melted in Oleum Camelliae.
Step 2, by 1g quicklime suitable quantity of water furnishing lime cream.
3rd step, with the heating of slow fire limit, under the low rate mixing of limit, successively the quicklime of 4g berberine hydrochloride, 15g bletilla striata extract, 15g Radix Angelicae Dahuricae extract, 2.5g Flos Carthami extract, 5g Fructus Gardeniae extract, 1.25g Rhizoma Dioscoreae Zingiberensis extract, 10g Borneolum Syntheticum and step 2 breast is slowly joined in the Oleum Camelliae-Cera Flava liquid of step one, after medicine adds, stir 30min again, then dry in the air to room temperature, namely complete the preparation of burn and scald ointment.
Here is the Clinic Case of unguentum of the present invention:
Case one: Ma, female, 22 years old, to be burnt right lower limb and instep portion by concentrated sulphuric acid, gross area 110cm
2.Burn degree is minor burn and II degree burn, local deep ii degree burn (certain hospital diagnosis).Wound surface applies the ointment of embodiment 3 after treatment, at once pain relieving.The healing in 3 days of minor burn wound surface; Severe burn wound surface covers and starts decrustation with this medicine after 8 days, within 32 days, cures, and scalds position without cicatrix.
Case two: Zhao so-and-so, man, 4 years old, out of doors by fire burn.Mainly burn in being positioned at two upper limb and the right hand palm, upper extremity pain is severe; Right hand burn of palm is serious, and patient, to its analgesia sense, is III degree burn.The ointment of the embodiment of the present invention 2 is used to apply, pain relieving at once.2nd day, the wound surface color of two upper limb turned shallow, is coated with and uses this medicine, and recovery from illness in 7 days, without cicatrix.Through using this ointment, the right hand starts decrustation after slapping 12 days, and recovery from illness in 39 days, functional rehabilitation is normal, without cicatrix.
Case three: Liu so-and-so, man, 19 years old, right lower limb and instep were scalded by boiled water, and wound surface is red and swollen, has many blisters, has an intense pain.Use the ointment of the embodiment of the present invention 2 to apply wound surface, recovery from illness in 6 days, wound surface does not stay cicatrix.
Claims (2)
1. treat the unguentum of empyrosis for one kind, it is characterized in that the component comprising following content: the Rhizoma Dioscoreae Zingiberensis extract of 0.5-2 weight portion, the bletilla striata extract of 15 weight portions, the Radix Angelicae Dahuricae extract of 15 weight portions, the Flos Carthami extract of 2.5 weight portions, the Fructus Gardeniae extract of 5 weight portions, the berberine hydrochloride of 2-6 weight portion, the Borneolum Syntheticum of 10 weight portions, the quicklime of 1 weight portion, the Oleum Camelliae of 160 weight portions, the Cera Flava of 160 weight portions.
2. treat a preparation method for the unguentum of empyrosis as claimed in claim 1, it is characterized in that comprising the steps:
(1) Oleum Camelliae of 160 weight portions is heated, the Cera Flava of 160 weight portions is added wherein, makes Cera Flava be melted in Oleum Camelliae;
(2) by the quicklime of 1 weight portion suitable quantity of water furnishing lime cream;
(3) with under the heating of slow fire limit, limit low rate mixing, successively the lime cream that the Rhizoma Dioscoreae Zingiberensis extract of the Fructus Gardeniae extract of the Flos Carthami extract of the Radix Angelicae Dahuricae extract of the bletilla striata extract of the berberine hydrochloride of 2-6 weight portion, 15 weight portions, 15 weight portions, 2.5 weight portions, 5 weight portions, 0.5-2 weight portion, the Borneolum Syntheticum of 10 weight portions and step (2) are obtained is slowly joined in the obtained Oleum Camelliae-Cera Flava liquid of step (1), after medicine adds, stir 30min again, then dry in the air to room temperature, obtain product.
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN105343332A (en) * | 2015-11-23 | 2016-02-24 | 湖南科技大学 | Herba artemisiae capillariae rhizoma polygoni cuspidati ointment, and preparation method thereof |
CN109172583A (en) * | 2018-08-27 | 2019-01-11 | 康宗华 | A kind of pharmaceutical composition for burn and scald knife wound and preparation method thereof and purposes |
CN110251547A (en) * | 2019-06-05 | 2019-09-20 | 赣南医学院 | A kind of safflower tea oil emulsifiable paste and preparation method thereof |
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CN105343332A (en) * | 2015-11-23 | 2016-02-24 | 湖南科技大学 | Herba artemisiae capillariae rhizoma polygoni cuspidati ointment, and preparation method thereof |
CN109172583A (en) * | 2018-08-27 | 2019-01-11 | 康宗华 | A kind of pharmaceutical composition for burn and scald knife wound and preparation method thereof and purposes |
CN110251547A (en) * | 2019-06-05 | 2019-09-20 | 赣南医学院 | A kind of safflower tea oil emulsifiable paste and preparation method thereof |
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