CN104383225A - Traditional Chinese medicine granules for controlling heatstroke of laying hens and preparation method thereof - Google Patents

Traditional Chinese medicine granules for controlling heatstroke of laying hens and preparation method thereof Download PDF

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Publication number
CN104383225A
CN104383225A CN201410743011.9A CN201410743011A CN104383225A CN 104383225 A CN104383225 A CN 104383225A CN 201410743011 A CN201410743011 A CN 201410743011A CN 104383225 A CN104383225 A CN 104383225A
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chinese medicine
medicine granules
heatstroke
traditional chinese
preparation
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CN201410743011.9A
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Chinese (zh)
Inventor
刘鼎阔
王立红
赵云英
赵晶晶
张俊霞
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Dingzheng Animal Pharmaceutical Tianjin Co Ltd
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Dingzheng Animal Pharmaceutical Tianjin Co Ltd
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Priority to CN201410743011.9A priority Critical patent/CN104383225A/en
Publication of CN104383225A publication Critical patent/CN104383225A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268Asarum (wild ginger)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/344Codonopsis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8964Anemarrhena
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Inorganic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)
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Abstract

The invention relates to traditional Chinese medicine granules for controlling heatstroke of laying hens. The traditional Chinese medicine granules comprise gypsum, rhizoma anemarrhenae, burdock, honeysuckle, fructus forsythiae, asarum and codonopsis pilosula. The preparation method of the traditional Chinese medicine granules comprises the following steps: weighing the components according to the ratio, adding water to decoct twice, merging the filtrate, standing, concentrating, drying, grinding, adding cane sugar, granulating, screening, drying, and screening again, thereby obtaining the finished product. During use, the traditional Chinese medicine granules are mixed with the feed at a certain ratio, the mixture is eaten by sick chicken, and after the medicine is taken for a period of time, the feed intake of the sick chicken is increased, the water consumption is reduced, the spirit and action capacities are restored, the body temperature restores to be normal, the growth and development and laying rate after healing are normal, the preparation and administration are convenient, the storage and transport are also convenient, and the traditional Chinese medicine granules do not have any residue or any toxic or side effect after drug administration.

Description

A kind of Chinese medicine granules for preventing and treating laying hen heatstroke and preparation method thereof
Technical field
The invention belongs to laying hen heatstroke treatment technology field, especially a kind of Chinese medicine granules for preventing and treating laying hen heatstroke and preparation method thereof.
Background technology
Laying hen heatstroke is also known as heat exhaustion, be come from sunlight direct irradiation and come from the too high general name of ambient temperature, it is the commonly encountered diseases of heat laying hen in season, according to surveying and determination, the ambient temperature becoming chicken desirable is 18 ~ 22 DEG C, and in this temperature range, chicken growth is the fastest, efficiency of feed utilization is also the highest, and too high ambient temperature will produce very adverse influence to chicken.During the broiling summer, when temperature reaches more than 32 DEG C, will cause chicken physiology and spiritual a series of untoward reaction, now, chicken just there will be heatstroke phenomenon.Time one is long, and gently then impact grows and lays eggs, and heatstroke can be caused rapidly time serious dead.Therefore, summer strengthens the prevention to chicken heatstroke, and it is very necessary that generation heatstroke is treated in time.
At present, common prevention and controls is artificial spraying, water is spread to reduce the heat of hen house in ground, strengthen ventilation and heat in addition, also can use some additives or cooling feedstuff, some anti-stress class medicaments also can be used after laying hen heatstroke, but these pharmaceutical treatment effects are deteriorated gradually, be badly in need of the medicament of summer-heat disease chicken in a kind of can efficiently treatment.
Summary of the invention
The object of the invention is to overcome the deficiencies in the prior art, a kind of Chinese medicine granules for preventing and treating laying hen heatstroke that scientific matching, therapeutic effect are good, have no side effect is provided.
The technical scheme that the present invention takes is:
For preventing and treating a Chinese medicine granules for laying hen heatstroke, it is characterized in that: comprise the following component mixed by weight:
And, comprise the following component mixed by weight:
Another object of the present invention is to provide a kind of preparation method of the Chinese medicine granules for preventing and treating laying hen heatstroke, it is characterized in that: comprise the following steps:
(1) take Gypsum Fibrosum, the Rhizoma Anemarrhenae, Fructus Arctii, Flos Lonicerae, Fructus Forsythiae, Herba Asari, Radix Codonopsis by metering, add in the clear water of 10 times of weight, then decoct twice;
(2) first time decocted after 2 hours, and filtrate is for subsequent use, and the clear water that medicinal residues add 10 times of weight carries out second time decoction, and the time is 1.5 hours, and filtrate is for subsequent use;
(3) the filtrate of twice merged, leave standstill 24 hours, get supernatant, when being concentrated into 80 degrees Celsius, relative density is 1.28;
(4) pulverize after step product (3) being dried at 60 ~ 70 degrees Celsius, add sucrose, stir;
(5) step product is (4) added granulator granulation, granule crosses 70 degrees Celsius of oven dry again after 80 mesh sieves, obtains finished product after 80 mesh sieves.
Another object of the present invention is to provide a kind of using method of the Chinese medicine granules for preventing and treating laying hen heatstroke, it is characterized in that: mixed by weight 1:400 with feedstuff by the medicament of claim 1 or 2, for sick chicken food, and continuous use 5 days.
Advantage of the present invention and good effect are:
In the present invention, take Gypsum Fibrosum, the Rhizoma Anemarrhenae, Fructus Arctii, Flos Lonicerae, Fructus Forsythiae, Herba Asari, Radix Codonopsis, decoct with water twice by metering, leave standstill after merging filtrate, concentrated, pulverize after drying, add sucrose, pelletize is sieved post-drying, and sieve obtained finished product again.Mix with feedstuff by a certain percentage during use, then for sick chicken food, after continuous use a period of time, the feed intake of sick chicken rises, and amount of drinking water declines, spirit and mobility are recovered, body temperature also recovers normal, and after curing, growth promoter and laying rate are all very normal, preparation and medication all very convenient, storage, convenient transportation, noresidue after medication, have no side effect.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further described, and following embodiment is illustrative, is not determinate, can not limit protection scope of the present invention with following embodiment.
For preventing and treating a Chinese medicine granules for laying hen heatstroke, innovation of the present invention is: comprise the following component mixed by weight:
Preferred scheme is: comprise the following component mixed by weight:
Each Chinese medicine all meets " Chinese veterinary pharmacopoeia " version two ministerial standard in 2010.Gypsum Fibrosum clearing away heat-fire in medicine of the present invention, relieving restlessness is quenched the thirst; Rhizoma Anemarrhenae clearing away heat-fire; Fructus Arctii dispelling wind and heat pathogens, Flos Lonicerae heat-clearing and toxic substances removing, dispelling wind and heat pathogens; Fructus Forsythiae heat-clearing and toxic substances removing, dispelling wind and heat pathogens; Herba Asari Herba Asari is sensible, warming the lung to resolve fluid-retention; Radix Codonopsis spleen reinforcing lung qi, enriches blood, promotes the production of body fluid; All medicines share, and play heat clearing away altogether, dispelling wind and heat pathogens, effect of removing dampness.
Embodiment 1
For preventing and treating the Chinese medicine granules of laying hen heatstroke, be made up of following component: 11 parts, Gypsum Fibrosum, the Rhizoma Anemarrhenae 12 parts, Fructus Arctii 10 parts, Flos Lonicerae 10 parts, Fructus Forsythiae 10 parts, Herba Asari 7 parts, Radix Codonopsis 7 parts.
(1) take Gypsum Fibrosum, the Rhizoma Anemarrhenae, Fructus Arctii, Flos Lonicerae, Fructus Forsythiae, Herba Asari, Radix Codonopsis by metering, add in the clear water of 10 times of weight, then decoct twice;
(2) first time decocted after 2 hours, and filtrate is for subsequent use, and the clear water that medicinal residues add 10 times of weight carries out second time decoction, and the time is 1.5 hours, and filtrate is for subsequent use;
(3) the filtrate of twice merged, leave standstill 24 hours, get supernatant, when being concentrated into 80 degrees Celsius, relative density is 1.28;
(4) pulverize after step product (3) being dried at 60 ~ 70 degrees Celsius, add sucrose, stir;
(5) step product is (4) added granulator granulation, granule crosses 70 degrees Celsius of oven dry again after 80 mesh sieves (180 μm ± 7.6 μm), obtains finished product after 80 mesh sieves (180 μm ± 7.6 μm).
Embodiment 2
For preventing and treating the Chinese medicine granules of laying hen heatstroke, be made up of following component: 15 parts, Gypsum Fibrosum, the Rhizoma Anemarrhenae 12 parts, Fructus Arctii 12 parts, Flos Lonicerae 11 parts, Fructus Forsythiae 11 parts, Herba Asari 10 parts, Radix Codonopsis 9 parts.
Above-mentioned compound Chinese medicinal preparation its preparation method, is undertaken by embodiment 1.
Embodiment 3
For preventing and treating the Chinese medicine granules of laying hen heatstroke, be made up of following component: 15 parts, Gypsum Fibrosum, the Rhizoma Anemarrhenae 10 parts, Fructus Arctii 10 parts, Flos Lonicerae 9 parts, Fructus Forsythiae 9 parts, Herba Asari 8 parts, Radix Codonopsis 8 parts.
Above-mentioned compound Chinese medicinal preparation its preparation method, is undertaken by embodiment 1.
Embodiment 4
For preventing and treating the Chinese medicine granules of laying hen heatstroke, be made up of following component: 15 parts, Gypsum Fibrosum, the Rhizoma Anemarrhenae 13 parts, Fructus Arctii 12 parts, Flos Lonicerae 10 parts, Fructus Forsythiae 10 parts, Herba Asari 10 parts, Radix Codonopsis 8 parts.
Above-mentioned compound Chinese medicinal preparation its preparation method, is undertaken by embodiment 1.
Clinical trial:
Administering mode: drinking water administration, 2.5g, every 1kg feedstuff, uses 3 ~ 5 days continuously.
Such as: in July, 2011, there is mouth breathing in certain plant 5500 laying hens, and dyspnea, sends obvious snore in part chicken larynx; Feed intake declines, and part chicken is gone on a hunger strike, and drinking-water significantly increases; Lethargy, movable minimizing, part chicken crouches at the bottom of cage; Cockscomb cyanosis, body temperature is up to more than 45 DEG C, and poor growth, laying rate reduces, and occurs dead.Cut open the visible muscle of the dead chicken of inspection pale, soft, in sample outward appearance of cooking meat; Blood is atropurpureus, solidifies bad, liver matter is crisp, enlargement, aubergine, cardiac muscle expansion, pulmonary congestion, hemorrhage and edema, some intestinals have catarrhal inflammation; Cloaca mucosa is congested, hemorrhage.Be diagnosed as laying hen heatstroke, then use embodiment 3 medicine, medication is after 3 ~ 5 days, and do not carry out compared with medication therapy groups, and have no mouth breathing, snore hour, feed intake increases, and temperature recovery is normal, laying rate apparently higher than non-administered group, and without dead chicken.
In the present invention, take Gypsum Fibrosum, the Rhizoma Anemarrhenae, Fructus Arctii, Flos Lonicerae, Fructus Forsythiae, Herba Asari, Radix Codonopsis, decoct with water twice by metering, leave standstill after merging filtrate, concentrated, pulverize after drying, add sucrose, pelletize is sieved post-drying, and sieve obtained finished product again.Mix with feedstuff by a certain percentage during use, then for sick chicken food, after continuous use a period of time, the feed intake of sick chicken rises, and amount of drinking water declines, spirit and mobility are recovered, body temperature also recovers normal, and after curing, growth promoter and laying rate are all very normal, preparation and medication all very convenient, storage, convenient transportation, noresidue after medication, have no side effect.

Claims (4)

1. for preventing and treating a Chinese medicine granules for laying hen heatstroke, it is characterized in that: comprise the following component mixed by weight:
2. a kind of Chinese medicine granules for preventing and treating laying hen heatstroke according to claim 1, is characterized in that: comprise the following component mixed by weight:
3. the preparation method of a kind of Chinese medicine granules for preventing and treating laying hen heatstroke according to claim 1 and 2, is characterized in that: comprise the following steps:
(1) take Gypsum Fibrosum, the Rhizoma Anemarrhenae, Fructus Arctii, Flos Lonicerae, Fructus Forsythiae, Herba Asari, Radix Codonopsis by metering, add in the clear water of 10 times of weight, then decoct twice;
(2) first time decocted after 2 hours, and filtrate is for subsequent use, and the clear water that medicinal residues add 10 times of weight carries out second time decoction, and the time is 1.5 hours, and filtrate is for subsequent use;
(3) the filtrate of twice merged, leave standstill 24 hours, get supernatant, when being concentrated into 80 degrees Celsius, relative density is 1.28;
(4) pulverize after step product (3) being dried at 60 ~ 70 degrees Celsius, add sucrose, stir;
(5) step product is (4) added granulator granulation, granule crosses 70 degrees Celsius of oven dry again after 80 mesh sieves, obtains finished product after 80 mesh sieves.
4. for preventing and treating a using method for the Chinese medicine granules of laying hen heatstroke, it is characterized in that: the medicament of claim 1 or 2 is mixed by weight 1:400 with feedstuff, for sick chicken food, continuous use 5 days.
CN201410743011.9A 2014-12-08 2014-12-08 Traditional Chinese medicine granules for controlling heatstroke of laying hens and preparation method thereof Pending CN104383225A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104938842A (en) * 2015-06-19 2015-09-30 安徽牧翔禽业有限公司 Spotted-brown chicken feed additive capable of preventing heatstroke
CN105233049A (en) * 2015-11-05 2016-01-13 农鑫高科(北京)科技开发有限公司 Traditional Chinese medicinal composition used for preventing and treating summer heat injury of chickens, and prevention and treatment method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104938842A (en) * 2015-06-19 2015-09-30 安徽牧翔禽业有限公司 Spotted-brown chicken feed additive capable of preventing heatstroke
CN105233049A (en) * 2015-11-05 2016-01-13 农鑫高科(北京)科技开发有限公司 Traditional Chinese medicinal composition used for preventing and treating summer heat injury of chickens, and prevention and treatment method thereof

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Application publication date: 20150304