CN104367862A - 一种治疗尿道结石的中药组合物 - Google Patents
一种治疗尿道结石的中药组合物 Download PDFInfo
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Abstract
本发明涉及一种治疗尿道结石的中药组合物，它是由下列重量配比的原料药物组成的：王不留行15-35g，海金沙10-30g，滑石10-30g，皂刺10-30g，扁蓄5-25g，猪苓5-25g，泽漆5-25g，木通5-25g，石韦5-25g，瞿麦5-25g，车前子5-25g，荷梗5-25g，炒栀子5-20g，甘草5-20g，金丝草5-20g，竹叶10-20g，灯芯草5-20g。本发明的中药组合物均采用天然的中药原料，其配制简便、药源广、成本低，疗效显著，药性平和，具有清热利湿，活血化瘀、通调气血，祛淤热、通阻滞，补益肾气，行气利尿，排石通淋的功效，有效率达96.67％，治愈率达76.67％。
Description
技术领域
本发明涉及一种传统草药的未确定结构的医用配制品，具体地说是一种治疗尿道结石的中药组合物。
背景技术
尿道结石是泌尿***的常见病，引起尿道结石的原因很多。尿道结石分原发性和继发性结石两类。原发性尿道结石少见，多在尿道已有尿道狭窄、尿道憩室和尿道异物等症状的基础上发生；绝大多数继发性尿道结石是膀胱结石或上***排出过程中经过尿道时被阻所形成。目前，临床上对尿道结石无特殊良药，大多采用排石类药为主，并且易对药物产生依赖性，停药后易复发。
中医认为，尿道结石形成，主要是湿热蕴结于下焦。克悠饮食不当，恣食膏粱厚味、辛辣湿热之品所致，或由肝气郁结，累及膀胱气化，或由房劳过度导致脾肾两亏。表现为排尿困难，排尿费力，可呈滴沥状，有时出现尿流中断及尿潴留。
根据中医理论，针对尿道结石的发病机理，以清热利湿，活血化瘀、通调气血，补益肾气，行气利尿，排石通淋为治疗原则，以达到标本兼治的目的
发明内容
本发明的目的就是为了克服上述现有的技术不足，根据中医理论，通过数年的药物筛选和反复临床验证，提供一种配伍合理，药源广，成本低，疗效显著的治疗尿道结石的中药组合物。
本发明解决其技术问题所采用的技术方案是：一种治疗尿道结石的中药组合物，其特征在于它是由下列重量配比的原料药物组成的：王不留行15-35g，海金沙10-30g，滑石10-30g，皂刺10-30g，扁蓄5-25g，猪苓5-25g，泽漆5-25g，木通5-25g，石韦5-25g，瞿麦5-25g，车前子5-25g，荷梗5-25g，炒栀子5-20g，甘草5-20g，金丝草5-20g，竹叶10-20g，灯芯草5-20g。
本发明的优选技术方案是：一种治疗尿道结石的中药组合物，其特征在于它是由下列重量配比的原料药物组成的：王不留行25g，海金沙20g，滑石20g，皂刺20g，扁蓄15g，猪苓15g，泽漆15g，木通15g，石韦15g，瞿麦15g，车前子15g，荷梗15g，炒栀子10g，甘草10g，金丝草10g，竹叶15g，灯芯草10g。
本发明中药组合物是在传统中医理论和临床经验指导下，精选药物组方，其原料成本低，治疗尿道结石病疗效高，无毒副作用。本发明中药组合物中：王不留行【性味】苦，平；【归经】归肝，胃经；【功能主治】有活血通经，下乳的功效，用于痛经，闭经，乳汁不下，乳痈。海金沙【性味】甘，寒；【归经】归小肠，膀胱经；【功能主治】有利水通淋的功效，用于热淋，石淋，全身肿满。滑石【性味】甘，淡，寒；【归经】归胃，膀胱经；【功能主治】有利水通淋，清解暑热的功效，用于小便不利，淋沥涩痛，暑热烦渴，湿温胸闷，湿热泄泻，湿疹，痱子。皂刺【性味】辛，温；【归经】肝，肺经；【功能主治】有消毒透脓，搜风、杀虫的功效，用于痈疽肿毒，瘰疬，疮疹顽癣，产后缺乳，胎衣不下，疠风。萹蓄【性味】苦，微寒；【归经】归膀胱经；【功能主治】有利水通淋的功效；用于热淋，血淋，皮肤湿疹，***湿疹。猪苓【性味】平，甘，淡；【归经】肾，膀胱经；【功能主治】有利水渗湿的功效，用于小便不利，水肿，泄泻，淋浊，带下。泽漆【性味】辛苦，凉，有毒；【归经】归大，小肠，脾；【功能主治】有行水，消痰，杀虫，解毒的功效，用于水气肿满，痰饮喘咳，疟疾，菌痢，瘰疬，癣疮，结核性痿管，骨髓炎。木通【性味】苦，寒；【归经】归心，小肠，膀胱经；【功能主治】有利水通淋，泄热下乳的功效，用于小便不利，淋沥涩痛，口舌生疮，乳汁不多，湿热痹症。石韦【性味】苦，甘，微寒【归经】归肺，膀胱经；【功能主治】有利水通淋，化痰止咳的功效，用于热淋，石淋，血淋，水肿，肺热咳嗽。瞿麦【性味】苦，寒；【归经】归心，小肠，膀胱经；【功能主治】有利水通淋的功效，用于热淋，血淋，小便不利。车前子【性味】甘，寒；【归经】归肾，肝，肺经；【功能主治】有利水通淋，利湿止泻，清肝明目，清肺化痰，用于小便不利，水肿，淋证，暑湿泄泻，肝热目赤肺热咳嗽。荷梗【功能主治】有清热解暑，通气行水的作用。炒栀子【性味】苦，寒；【归经】入心，肺，胃，三焦经；【功能主治】有清热利水，祛火除烦，凉血解毒的功效，用于治疗热病引起的心烦，不安以及肝胆湿热所致的黄疸，发热。甘草【性味】甘，平；【归经】归心，脾，肺，胃经；【功能主治】有补脾益气，润肺止咳，清热解毒，缓解止痛，缓和药性的功效。金丝草【性味】性凉，味平淡；【功能主治】有清热，利水，通淋的功效。竹叶【性味】甘淡，寒；【归经】归心，肺，胆，胃经；【功能主治】有清热除烦，生津利尿的功效，用于治热病烦渴，小儿惊痫，面赤，小便短亦，口糜舌疮。灯芯草【性味】微寒，甘，淡；【归经】归心，肺小肠经；【功能主治】有利水通淋，清心除烦的功效，用于小便不利，淋沥涩痛，心热烦躁，小儿夜啼。本发明具有清热利湿，活血化瘀、通调气血，祛淤热、通阻滞，补益肾气，行气利尿，排石通淋的功效，对尿道结石达到标本兼治的目的。
本发明组合物的组分均采用天然的中药原料，其配制简便、药源广、成本低。其遵循中医的处方用药原则，各种组分药物采用水煎服用。经临床应用验证，其疗效显著，作用可靠，药性平和，未出现毒副作用，总有效率96.67％，治愈率达76.67％。
具体实施方式：
实施例1：一种治疗尿道结石的中药组合物，其特征在于它是由下列重量配比的中药原料组成的：王不留行15g，海金沙10g，滑石10g，皂刺10g，扁蓄5g，猪苓5g，泽漆5g，木通5g，石韦5g，瞿麦5g，车前子5g，荷梗5g，炒栀子5g，甘草5g，金丝草5g，竹叶10g，灯芯草5g。
实施例2：一种治疗尿道结石的中药组合物，其特征在于它是由下列重量配比的中药原料组成的：王不留行20g，海金沙15g，滑石15g，皂刺20g，扁蓄10g，猪苓10g，泽漆10g，木通10g，石韦10g，瞿麦10g，车前子10g，荷梗10g，炒栀子6g，甘草8g，金丝草8g，竹叶10g，灯芯草6g。
实施例3：一种治疗尿道结石的中药组合物，其特征在于它是由下列重量配比的中药原料组成的：王不留行20g，海金沙20g，滑石15g，皂刺15g，扁蓄15g，猪苓15g，泽漆10g，木通10g，石韦12g，瞿麦12g，车前子10g，荷梗15g，炒栀子8g，甘草8g，金丝草10g，竹叶10g，灯芯草10g。
实施例4：一种治疗尿道结石的中药组合物，其特征在于它是由下列重量配比的中药原料组成的：王不留行30g，海金沙18g，滑石25g，皂刺20g，扁蓄25g，猪苓12g，泽漆12g，木通15g，石韦25g，瞿麦12g，车前子15g，荷梗12g，炒栀子20g，甘草15g，金丝草10g，竹叶16g，灯芯草8g。
实施例5：一种治疗尿道结石的中药组合物，其特征在于它是由下列重量配比的中药原料组成的：王不留行35g，海金沙30g，滑石25g，皂刺25g，扁蓄25g，猪苓20g，泽漆25g，木通25g，石韦15g，瞿麦12g，车前子15g，荷梗15g，炒栀子10g，甘草20g，，金丝草20g，竹叶20g，，灯芯草20g。
本发明实施例中的中药组合物按常规的水煎法制取药剂。具体方法如下：取本发明组方的中药原料药物放入容器中，先加水浸泡，加冷水漫过药面，浸泡60分钟，再加水没过药面约10厘米，进行第一次煎煮，先用武火煎煮，煮沸后用文火煎煮20～30分钟，滤出取药液汁200ml；第二煎煮，加水没过药面约6厘米，水沸后煎煮15～20分钟，滤出取药液汁200ml。两次煎煮取得药液汁合并。
一种治疗尿道结石的中药组合物临床疗效总结：
一、一般性资料：本中药组合物应用于临床观察病60例，其中男48例，女12例，年龄40～72岁。病程最短者6个月，最长者达10年。
二、诊断标准：
(1)排尿困难，尿流滴沥或尿潴留；
(2)B超检查，可以发现0.2mm以上的结石。
三、用法用量：临床应用时，组合物中的组分、用量根据患者的体重、年龄及症状酌情增减。10剂为一疗程，一天一剂，水煎两遍取汁约400ml，分早、晚两次饭前半小时温热服用。
四、疗效标准：
(1)治愈：临床主要症状及体征消失，结石量明显减少；
(2)有效：主要症状明显减轻，结石量有所减少；
(3)无效；主要症状无变化，也未恶化。
五、治疗效果：临床观察病例中，服药2-6个疗程，治愈46例，有效12例，无效2例。治疗期间未发生毒副作用。
六、典型病例：
病例1：狄某，男，37岁，平时生活作息混乱，排尿困难3月余，服用本发明的中药组合物制备的药剂2个疗程，正常作息，症状基本消失，经B超检查证实，排尿正常。
病例2：李某，女，62岁，6年前，在医院做过碎石术。近期发现只要稍微劳累，腹部便反复性疼痛，还伴有恶心的症状，在医院检查后，发现尿道里又出现了两颗结石。服用本发明的中药组合物制备的药剂4个疗程，疼痛，恶心的症状明显减轻，经B超检查证实，结石消失。
Claims (2)
1.一种治疗尿道结石的中药组合物，其特征在于它是由下列重量配比的原料药物组成的：王不留行15-35g，海金沙10-30g，滑石10-30g，皂刺10-30g，扁蓄5-25g，猪苓5-25g，泽漆5-25g，木通5-25g，石韦5-25g，瞿麦5-25g，车前子5-25g，荷梗5-25g，炒栀子5-20g，甘草5-20g，金丝草5-20g，竹叶10-20g，灯芯草5-20g。
2.根据权利要求1所述的一种治疗尿道结石的中药组合物，其特征在于它是由下列重量配比的原料药物组成的：王不留行25g，海金沙20g，滑石20g，皂刺20g，扁蓄15g，猪苓15g，泽漆15g，木通15g，石韦15g，瞿麦15g，车前子15g，荷梗15g，炒栀子10g，甘草10g，金丝草10g，竹叶15g，灯芯草10g。
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