CN104351774A - Healthcare composition and preparation method thereof - Google Patents
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- CN104351774A CN104351774A CN201410579123.5A CN201410579123A CN104351774A CN 104351774 A CN104351774 A CN 104351774A CN 201410579123 A CN201410579123 A CN 201410579123A CN 104351774 A CN104351774 A CN 104351774A
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- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 230000000242 pagocytic effect Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 229930184989 physalin Natural products 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000009781 safety test method Methods 0.000 description 1
- 239000012266 salt solution Substances 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 239000000932 sedative agent Substances 0.000 description 1
- 230000001624 sedative effect Effects 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- JAJWGJBVLPIOOH-IZYKLYLVSA-M sodium taurocholate Chemical compound [Na+].C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(=O)NCCS([O-])(=O)=O)C)[C@@]2(C)[C@@H](O)C1 JAJWGJBVLPIOOH-IZYKLYLVSA-M 0.000 description 1
- 239000011122 softwood Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000007619 statistical method Methods 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 239000004575 stone Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000041 toxicology testing Toxicity 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 230000002936 tranquilizing effect Effects 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 238000002562 urinalysis Methods 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- NCYCYZXNIZJOKI-UHFFFAOYSA-N vitamin A aldehyde Natural products O=CC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C NCYCYZXNIZJOKI-UHFFFAOYSA-N 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
- 230000002618 waking effect Effects 0.000 description 1
- XACHQDDXHDTRLX-HZXCUAKRSA-N zeaxanthin dipalmitate Chemical compound CC1(C)CC(OC(=O)CCCCCCCCCCCCCCC)CC(C)=C1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CC(OC(=O)CCCCCCCCCCCCCCC)CC1(C)C XACHQDDXHDTRLX-HZXCUAKRSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/30—Dietetic or nutritional methods, e.g. for losing weight
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L11/00—Pulses, i.e. fruits of leguminous plants, for production of food; Products from legumes; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
- A23L19/10—Products from fruits or vegetables; Preparation or treatment thereof of tuberous or like starch containing root crops
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L25/00—Food consisting mainly of nutmeat or seeds; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L7/00—Cereal-derived products; Malt products; Preparation or treatment thereof
- A23L7/10—Cereal-derived products
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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Abstract
The invention discloses a healthcare composition and a preparation method thereof. The healthcare composition comprises the following raw materials in parts by weight: 800-1,200 parts of poria cocos, 800-1,200 parts of adenophora stricta, 800-1,200 parts of radix polygonati officinalis, 800-1,200 parts of lilies, 800-1,200 parts of yams, 800-1,200 parts of black sesame, 800-1,200 parts of hyacinth beans, 400-600 parts of pine nuts, 400-600 parts of medlar and 400-600 parts of walnuts. The healthcare composition has the effects of consolidating basis, nourishing yin, reinforcing the kidney and improving vision, is rich in nutrition, can be separately eaten as breakfast, also can serve as a noodle food, a rice food, a drink, capsules, tablets or granules, has a very good conditioning effect on hypertension and diabetes, is prepared from pure natural raw materials, does not have toxic or side effects, and is suitable for people with fire excess from yin deficiency, deficiency of both vital energy and yin and weak constitution and people with hypertension, chronic pharyngitis, dizziness, diabetes and instable blood sugar.
Description
Technical field
The present invention relates to a kind of health food, especially a kind of health care composition with various health care functions formulated by medicine-food two-purpose article, belongs to nutrition and health care technical field.
Background technology
Modern is busy with one's work, pressure is large, towards nine evenings five, diet is irregular, particularly breakfast skipping or using subalimentation food as biscuit, instant noodles or fry as deep-fried twisted dough sticks etc. are general as breakfast phenomenon, breakfast is a most important meal among one day, for darg provides mental muscle power to support,, easily there is the symptoms such as blood sugar is unstable, dizzy in breakfast nutritious deficiency.On the other hand, along with the improvement of quality of life, it is high that fat content taken in by middle dinner diet, causes blood in human body in fat to form and change; Add that live and work pressure is large, run duration is few, and abnormal work and rest custom, cause modern's physique to decline, capacity of self-regulation also reduces, and easily occurs the symptoms such as hyperlipidemia and hypertension diabetes.
In recent years, because expanding economy living standards of the people improve constantly, long-term to take in dietetic nutrition unbalance, easily causes inferior health or cardiovascular and cerebrovascular disease, and people are to the larger more requirement that had the food demand of food therapy health effect to have.
" integration of drinking and medicinal herbs " is to one of contribution of mankind's most worthy among Chinese original medical science, the traditional Chinese medical science is always emphasized " medication is not as dietotherapy ", be that medicine has following several large outstanding advantage with food: one, Long-Time Service medicine therapy often produces various side effect and dependence, but also may impact the health of human body; And dietotherapy is effectively comparatively safe, toxic and side effect is little; What two, dietotherapy used is all food common in our daily life, and cheap, let us just can reach the object of conditioning in daily dining, and this is that expensive medical fee is incomparable; Three, food is the advantage that medicine also has no pain, allows people dispel slight illness in the process enjoying cuisines, avoids and have an injection, take medicine, even pain of surgery.
Under the enlightenment of motherland's traditional medicine, market also emerges a lot of dietotherapy class health food, but quality and effect uneven, a kind of multielement health care composition disclosed in patent 02131226.5, become to be grouped into by brown rice, scented rice, white sesameseed black soya bean etc. 26, each composition is expanded by bulking machine, far infrared baking, pulverize after high temperature flash distillation and microwave disinfection and make, and has raw material types many, adopts inconvenient.Technique simple coarse, can not preserve the shortcomings such as the original taste of each raw material.Patent 200910135828.7 discloses a kind of production method reducing health care's composition of after-dinner blood sugar of diabetes patients, and it is single that health care's composition that the method is produced has effect, can not nurse one's health the shortcoming of health comprehensively.
Summary of the invention
The object of the present invention is to provide a kind of safe and effective, toxic and side effect is little, take common food as primary raw material, cheap, the acceptable a kind of integration of drinking and medicinal herbs class of people reports physique person the health care's composition eaten for special.
Particularly, the present invention is realized by following technical scheme:
A kind of health care's composition, by weight, be made up of following raw material: Poria cocos 800-1200 part, the root of straight ladybell 800-1200 part, radix polygonati officinalis 800-1200 part, lily 800-1200 part, Chinese yam 800-1200 part, Semen sesami nigrum 800-1200 part, French beans 800-1200 part, pinenut 400-600 part, matrimony vine 400-600 part, walnut 400-600 part.
Preferably, a kind of health care's composition of the present invention, be made up of following raw material: Poria cocos 900-1100 part, the root of straight ladybell 900-1100 part, radix polygonati officinalis 900-1100 part, lily 900-1100 part, Chinese yam 900-1100 part, Semen sesami nigrum 900-1100 part, French beans 900-1100 part, pinenut 450-550 part, matrimony vine 450-550 part, walnut 450-550 part.
Preferably, a kind of health care's composition of the present invention, be made up of following raw material: Poria cocos 950-1050 part, the root of straight ladybell 950-1050 part, radix polygonati officinalis 950-1050 part, lily 950-1050 part, Chinese yam 950-1050 part, Semen sesami nigrum 950-1050 part, French beans 950-1050 part, pinenut 475-525 part, matrimony vine 475-525 part, walnut 475-525 part.
More preferably, a kind of health care's composition of the present invention, be made up of following raw material: 1000 parts, Poria cocos, the root of straight ladybell 1000 parts, radix polygonati officinalis 1000 parts, lily 1000 parts, Chinese yam 1000 parts, Semen sesami nigrum 1000 parts, 1000 parts, French beans, pinenut 500 parts, matrimony vine 500 parts, walnut 500 parts.
French beans of the present invention are Semen Lablab Album.
The preparation method of a kind of health care's composition of the present invention comprises the following steps:
1), get Poria cocos, the root of straight ladybell, radix polygonati officinalis, add 5-8 times amount soak by water 2-3 time, collecting decoction, filter, when filtrate being concentrated into 80 DEG C, relative density is 1.05 ~ 1.30, dry, pulverize, and obtains dried cream powder.
2), Semen Lablab Album is soaked in water 8-12h, and add 5-8 times amount soak by water 2-3h, at temperature 40 DEG C, forced air drying is≤5% to moisture, pulverizes as granule size is 90 object meal;
3), by yam slices, digestion 3-5min in boiling water, at temperature 40 DEG C, forced air drying to moisture is≤5%, pulverizes, obtains meal;
4), lily, Semen sesami nigrum, pinenut, matrimony vine, walnut coarse crushing under 0-(-4) DEG C condition, at temperature 40 DEG C, forced air drying to moisture is≤5%, at temperature 25 DEG C composition broken for granule size be 90 object meal;
5), by step 1) to 3) powder of gained and dried cream powder, use low temperature shock grinding machine, under-10 DEG C of conditions, vibrate 10min, being crushed to granule size is 800 object Ultramicro-powders; After mixing under 40 DEG C of conditions microwave disinfection 2h, add corresponding auxiliary material and be prepared as required product or direct packaging and get final product.
Step 2) in Semen Lablab Album soak before need to stir-fry at 70-80 DEG C 15 minutes cold removings.
Described health care's composition can make health care's wheaten food or rice eats food or drink.
The preparation that described health care's composition is made is capsule, tablet, granule.
The application of described health care's composition in the health food or medicine of prevention conditioning hypertension, diabetes conditions.
Technical solution of the present invention has following beneficial effect: first, the present invention selects has nourishing ingredients walnut, Semen sesami nigrum, pinenut and Chinese yam etc., be aided with multiple medicinal herb components lily, the root of straight ladybell, radix polygonati officinalis, the fruit of Chinese wolfberry, there is reinvigoration, enriching yin, reinforce the kidney, effect of improving eyesight, nutritious, the nutritional need of human body can be met, it can be eaten as breakfast separately, to hypertensive diabetes, there is good conditioning effect simultaneously, the raw material of the pure natural that the present invention adopts, bad side effect can not be produced, be applicable to fire excess from yin deficiency, deficiency of both qi and yin, void is not by complement matter personage and suffer from hypertension, chronic pharyngitis, time see dizziness, dim eyesight and diabetes glucose instability person.
Secondly, the present invention, according to the principle of chinese tradition medical science integration of drinking and medicinal herbs, selects medicinal material Poria cocos nature and flavor sweet, light, flat, has the function of clearing damp and promoting diuresis, beneficial spleen and stomach, antitoxic heart-soothing and sedative.Modern medicine study shows: Poria cocos has diuretic antihypertensive, hypoglycemic blood fat, can enhanced machine body immunity function, and polysaccharide has significantly antitumor and protect the liver dirty effect; Sweet, the micro-hardship of the root of straight ladybell cold nature, taste, there are nourishiing yin to clear away the lung-heat, expelling phlegm and arresting coughing effect, modern pharmacological research shows, its chemical composition contains radix glehniae sugar, bergaptene, the element of kidney tonifying, psoralen, cumarin and alkaloid etc., energy suppressor T cell, B cell hyperplasia, strengthen immunologic function, there is analgesia, fall hot phlegm-dispelling functions; Radix polygonati officinalis nature and flavor are sweet flat, have nourishing yin to moisten dryness, a function of cough-relieving of promoting the production of body fluid, and can be used for the cards such as heart failure, diabetes, high fat of blood, dryness of the mouth and throat, the few phlegm of dry cough, it contains sealwort spiral shell sterol, radix polygonati officinalis glucosides, sealwort furan steroline, flavones, anthraquinone, amino acid etc.There are hypoglycemic, blood pressure, blood fat, atherosclerotic plaque can be alleviated and formed, develop immunitypty, improve the effects such as serum hemolysin; Lily has effect of Yin nourishing and lung moistening, clearing away the heart fire and tranquillizing, containing lily glycosides, B Solanum aviculare Forst limit alkali, the compositions such as phenolic acid glyceride, propanoate ester derivatives and multiple sugar, there is cough-relieving, eliminate the phlegm, relieving asthma, the effects such as energy antifatigue, anti anoxia, enhancing hormone control function, Promote immunity function and enzyme system; Chinese yam nature and flavor are sweet flat, there is the function of strengtheninging the spleen and tonifying the lung, reinforcing the kidney benefit essence, it contains multiple batatasins, polysaccharide, mannocarolose, dopamine, hydrochloric acid Chinese yam alkali and multiple sterol and the composition such as amino acid, polyphenol oxidase, have and reduce blood sugar effect, can prevent and reduce diabetes, the motion of adjustment stomach, promote and recover gastric secretion, antitumor, promotion serum hemolysin production, promote macrophage phagocytic, promote lymphocyte transformation rate, develop immunitypty, anti-oxidant, anti-ageing function of waiting for a long time; Semen sesami nigrum nature and flavor are sweet flat, have nourishing liver and kidney, benefiting essence-blood, the breast that relaxes bowel, leads to function, for senile diabetes, anaemia and thrombocytopenic purpura, dizzy etc.; Matrimony vine has function that is nourishing liver and kidney, benefiting shrewd head.Containing LBP-X, palmitic acid, oleic acid, carotene, betaine, physalin, vitamin, amino acid and various trace elements etc., there is the change promoting and improve immunologic function, reduce lipid in transaminase and liver, promote that liver cell is newborn, there is hepatoprotective effect, hemangiectasis, effect such as reduction cholesterol, blood sugar etc.Walnut has kidney tonifying, ease constipation function, and main component has linoleic acid, oleic acid, leukotrienes, glycerine glycosides etc., has anti-oxidant, the anti-ageing effect of waiting for a long time; The function that Semen Lablab Album has invigorating the spleenization and relieves summer heat, containing compositions such as palmitic acid, linoleic acid, oleic acid, stearic acid, arachidic acid, stigmast acids; SEMEN PINI KORAIENSIS can be controlled dizzy a, moisturizing viscera, allays one's hunger, by chill miasma, qi-restoratives body, skin care.
The cooperation experiment of the above-mentioned 10 taste Chinese medicines in the present invention, wherein Poria cocos, radix polygonati officinalis, matrimony vine have hypoglycemic, blood pressure effect, Chinese yam, pinenut, lily, the root of straight ladybell, walnut and Semen sesami nigrum have benefiting action in addition, human body constitution can be strengthened, recover collective's capacity of self-regulation, promote the absorption of active ingredient and the performance of effect in Poria cocos, matrimony vine, radix polygonati officinalis.
Detailed description of the invention
Embodiment 1
Raw material: Poria cocos 800g, the root of straight ladybell 800g, radix polygonati officinalis 800g, lily 800g, Chinese yam 800g, Semen sesami nigrum 800g, French beans 800g, pinenut 600g, matrimony vine 600g, walnut 600g.
Preparation method:
1, get Poria cocos, the root of straight ladybell, radix polygonati officinalis, add 8 times amount soak by water 2 times, collecting decoction, filter, when filtrate being concentrated into 80 DEG C, relative density is 1.05, dry, pulverize, and obtains dried cream powder;
2, Semen Lablab Album stir-fries 15 minutes cold removings at 70 DEG C, soaks 8h, adds 5 times amount soak by water 2h, dry and pulverize as granule size is 90 object meal;
3, be cut at the thick yam slice of 3mm by the fresh Chinese yam washed, complete after section 3min in boiling water, and then at temperature 40 DEG C, forced air drying is 5% to moisture immediately, obtains dry yam slice; Pulverize as granule size is 90 object meal at temperature 25 DEG C;
4, lily, Semen sesami nigrum, pinenut, matrimony vine, walnut coarse crushing under-4 DEG C of conditions, be then dried to the meal that moisture is 5% under 40 DEG C of conditions, at temperature 25 DEG C composition broken for granule size be 90 object coarse yam powder;
5, by step 1 to the powder of 4 gained and dried cream powder, adopt low temperature shock grinding machine, under-10 DEG C of conditions, vibrate 10min, being crushed to granule size is 800 object Ultramicro-powders; Adopt microwave disinfection 2h under 40 DEG C of conditions after mixing, be prepared into corresponding product according to following technique:
1), by Ultramicro-powder after sterilization load in vacuum packaging bag, use multi-functional film sealing machine sealer to pack, brew with boiling hot boiling water, be used as the part of breakfast.
2) Ultramicro-powder 10% is got, by weight, rice flour 22%; Corn flour 20%, carry out and face after uniform mixing, the warm water that every part of coarse cereals face adds 0.4%35 DEG C carries out and face, 2 grams of yeast are added by Weight computation per kilogram coarse cereals face, dry coarse cereals face with during face, be 30-40 DEG C of bottom fermentation 30-40 minute in temperature, face time of waking up is 40-60 minute, awake intact steamed bun be put into steamer steams 15-20 minute after eat.
3), Ultramicro-powder of the present invention 80% ethanol makes softwood, crosses 14 mesh sieves, granulates, in about 60 DEG C dryings, and whole grain, encapsulated, every capsules 0.35g.
Usage and dosage: 3 times on the one, each 3.
Embodiment 2
Raw material: Poria cocos 1200g, the root of straight ladybell 1200g, radix polygonati officinalis 1200g, lily 1200g, Chinese yam 1200g, Semen sesami nigrum 1200g, French beans 1200g, pinenut 400g, matrimony vine 400g, walnut 400g.
Preparation method:
1, get Poria cocos, the root of straight ladybell, radix polygonati officinalis, add 8 times amount soak by water 3 times, collecting decoction, filter, when filtrate being concentrated into 80 DEG C, relative density is 1.30, dry, pulverize, and obtains dried cream powder;
2, Semen Lablab Album stir-fries 15 minutes cold removings at 80 DEG C, and be soaked in water 8h, adds 5 times amount soak by water 3h, dries and pulverize as granule size is 90 object meal;
3, be cut at the thick yam slice of 3mm by the fresh Chinese yam washed, complete after section 3min in boiling water, and then at temperature 40 DEG C, forced air drying is 5% to moisture immediately, obtains dry yam slice; Pulverize as granule size is 90 object coarse yam powder at temperature 25 DEG C;
4, lily, Semen sesami nigrum, pinenut, matrimony vine, walnut coarse crushing under-4 DEG C of conditions, be then dried to the meal that moisture is 5% under 40 DEG C of conditions, pulverizes as granule size is 90 object meal at temperature 25 DEG C;
5, by step 1 to the powder of 4 gained and dried cream powder, adopt low temperature shock grinding machine, under-10 DEG C of conditions, vibrate 10min, being crushed to granule size is 800 object Ultramicro-powders; Adopt microwave disinfection 2h under 40 DEG C of conditions after mixing, be prepared into corresponding product according to following technique:
1), by Ultramicro-powder after sterilization load in vacuum packaging bag, use multi-functional film sealing machine sealer to pack, brew with boiling hot boiling water, be used as the part of breakfast.
2), Ultramicro-powder 6%, flour 78%, salt 1.52%, water 13.3%, dietary alkali 1.18%, first be uniformly mixed with water, Ultramicro-powder and flour, add salt and dietary alkali and face again, raw material is fully mixed, becomes and there is plasticity, viscoelasticity and ductile graininess wetted surface group; Through placement slaking after an hour, by flaking machine, dough is rolled into certain thickness wearing, rip cutting becomes the noodles of one fixed width, noodles customized cut-off, passes through again the operations such as suspension is air-dry, cut-out, metering, packaging, namely goes out health care's noodles finished product.
3), Ultramicro-powder mixing after granulate, with the whole grain of 16 mesh sieve, adding 1% dolomol is lubricant, and add microcrystalline cellulose, amylum pregelatinisatum fully mixes, tabletted, and every sheet 0.35g, film coating, to obtain final product.
Usage and dosage: 3 times on the one, each 3.
Embodiment 3
Raw material: Poria cocos 1000g, the root of straight ladybell 1000g, radix polygonati officinalis 1000g, lily 1000g, Chinese yam 1000g, Semen sesami nigrum 1000g, Semen Lablab Album 1000g, pinenut 500g, matrimony vine 500g, walnut 500g.
Preparation method:
1, get Poria cocos, the root of straight ladybell, radix polygonati officinalis, add 6 times amount soak by water 2 times, collecting decoction, filter, when filtrate being concentrated into 80 DEG C, relative density is 1.20, dry, pulverize, and obtains dried cream powder;
2, Semen Lablab Album stir-fries 15 minutes cold removings at 70-80 DEG C, and be soaked in water 10h, adds 6 times amount soak by water 3h, dries and pulverize as granule size is 90 object meal;
3, be cut at the thick yam slice of 3mm by the fresh Chinese yam washed, complete after section 3min in boiling water, and then at temperature 40 DEG C, forced air drying is 5% to moisture immediately, obtains dry yam slice; Pulverize as granule size is 90 object meal at temperature 25 DEG C;
4, lily, Semen sesami nigrum, pinenut, matrimony vine, walnut coarse crushing under-4 DEG C of conditions, be then dried to the meal that moisture is 5% under 40 DEG C of conditions, pulverizes as granule size is 90 object coarse yam powder at temperature 25 DEG C;
5, by step 1 to the powder of 4 gained and dried cream powder, adopt low temperature shock grinding machine, under-10 DEG C of conditions, vibrate 10min, being crushed to granule size is 800 object Ultramicro-powders; Adopt microwave disinfection 2h under 40 DEG C of conditions after mixing, be prepared into corresponding product according to following technique:
1), by Ultramicro-powder after sterilization load in vacuum packaging bag, use multi-functional film sealing machine sealer to pack, brew with boiling hot boiling water, be used as the part of breakfast.
2), Ultramicro-powder 10%, flour 74%, salt 1.52%, water 13.3%, dietary alkali 1.18%, first be uniformly mixed with water, Ultramicro-powder and flour, add salt and dietary alkali and face again, raw material is fully mixed, becomes and there is plasticity, viscoelasticity and ductile graininess wetted surface group; Through placement slaking after an hour, by flaking machine, dough is rolled into certain thickness wearing, rip cutting becomes the noodles of one fixed width, noodles customized cut-off, passes through again the operations such as suspension is air-dry, cut-out, metering, packaging, namely goes out health care's noodles finished product.
3), add Ultramicro-powder 5% dextrin, pulverize, mixing, granulate, dry, whole grain, packs to obtain often bag of 1g.
Usage and dosage: 3 times on the one, each 1 bag.
Embodiment 4
Experimental example one, the hypoglycemic experiment of animal
(1) experiment material
1, given the test agent: the health care's composition made according to method described in the embodiment of the present invention 1.
2, animal: male mice, body weight 20 ± 2g, is provided by Guiyang Medical College Animal Experimental Study center.Indoor temperature 22 DEG C ~ 25 DEG C, raise under relative humidity 50% ~ 60% condition, be provided with feed, freely drink water.
3, high thermal energy fodder: lard 10%, sucrose 15%, yolk composition 15%, casein 5%, cholesterol 1.2%, sodium taurocholate 0.2%, calcium bicarbonate 0.6%, stone composition 0.4%, mouse maintain material 52.6%.
(2) experimental technique carries out with reference to the auxiliary hyperglycemic function method of inspection in " health food inspection and assessment technical specification " and operational procedure.
1, intact animal hypoglycemic experiment
Select healthy adult mouse, by the grouping of the fasting blood sugar level of 4 hours, select 1 control group and 1 dosage group at random.Control group gives the distilled water of same volume, and dosage group gives health care's composition of the present invention, continuous 30 days, surveys fasting blood sugar (fasting is with before experiment), compares two treated animal blood glucose values.
2, hyperglycemia model hypoglycemic experiment
2.1 modeling method
Select healthy adult mouse, adapt to after 1 day, get 15 animal fasting 4 hours at random, survey fasting blood-glucose, as this batch of animal basal plasma glucose value.Animal fasting subsequently 24 hours (freely drinking water), injection alloxan (using front Fresh) modeling, mouse 46mg/kg BW.iv.Animal fasting 4 hours after 5 days, surveys blood sugar, and blood glucose value 10-25mmol/L is hyperglycemia model success animal.
2.2 hyperglycemia model animal hypoglycemic experiments
Select hyperglycemia model animal by the grouping of the fasting blood sugar level of 4 hours, select 1 model control group and 3 dosage groups at random.Dosage group gives the embodiment of the present invention 1-3 health care composition, and model control group gives the distilled water of same volume, continuous 30 days, surveys fasting blood sugar (fasting is with before experiment), more each treated animal blood glucose value and blood sugar decline percentage.
(3) experimental result
1, the present invention is on the impact of normal mouse fasting blood-glucose: have no significant effect (P > 0.05) normal mouse fasting blood-glucose, experimental result is in table 1.
Table 1 the present invention is on the impact (s) of normal mouse fasting blood-glucose
Group | Blood glucose value mmol/L |
Control group | 5.0460.760 |
Dosage group | 5.110±1.080 |
2, hyperglycemia model hypoglycemic experiment
The result of 2.1 observation modelings: experimental result shows, the blood glucose value of model group mouse is 18.101 ± 3.280, is hyperglycemia model success animal, the results are shown in Table 2 between 10-25mmol/L.
Table 2 alloxan induced diabetes mouse model result (s)
Group | Blood glucose value mmol/L |
Model group | 18.101±3.280 |
2.2 hyperglycemia model animal hypoglycemic experiments: as shown in Table 3, the present invention's 3 groups of blood glucose values and blood sugar decline percentage all reduce, and compare with model group and have significant statistical significance (P < 0.01), experimental result is in table 3.
Table 3 the present invention is on the impact (s) of blood glucose in diabetic mice
Note: compare with model group, * * * P < 0.01
2.3 hyperglycemia model animal sugar tolerances experiments: dosage grouping and given the test agent give the time and test with hyperglycemia model animal hypoglycemic.Each treated animal fasting 4 hours, measure to glucose (namely 0 hour) blood glucose value, dosage group gives embodiment of the present invention product, model control group gives same volume solvent, each group oral administration of glucose 2.0g/kgBW after 15-20 minute, measure to each group blood glucose value of 0.5,2 hour after glucose, result shows that dosage group compares with model control group, and after giving glucose, 0.5,2 hour arbitrary time point blood sugar declines significant difference (P < 0.05).
Experimental example two, the hypotensive experiment of animal
(1) experiment material
1, animal used as test: regular grade SD rat, male and female half and half, body weight 200g ± 10g, is provided by Guiyang Medical College Experimental Animal Center by 60.
2, experimental drug: pure water, sodium chloride is analyzed pure, and health care's composition of the present invention, depressor contrasts medicinal kendir pressure-reducing sheet.
(2) experimental technique
1, group technology
Body weight randomized blocks are divided into groups, and are divided into 4 groups: blank group, model group, the embodiment of the present invention 2 groups, positive controls.15/group.
2, modeling method
Adopt high salt administration by gavage, the high level salt solution 1ml/ pcs/day of model group gavage every day 20%.Gavage 30 days.Blood pressure has statistical significance to be considered as modeling success with blank group than friendship.
3, experimental procedure
Interference method is in advance taked in 3.1 experiments.Of the present invention group every day gavage health care composition, positive controls gavage kendir pressure-reducing sheet suspension, blank group and model group gavage equal volume pure water, gavage 30 days, surveys body weight and amount of drinking water every day and observes urine volume.Each week measuring blood pressure 1 time.
3.2 from the 31st day, all the other respectively group beginning modelings except blank group.Survey body weight and amount of drinking water every day and observe urine volume.Each week measuring blood pressure 1 time.Until model group modeling success (compare with before modeling or compare blood pressure with blank group and raise and have statistical significance), contrast the difference of blood pressure between each group.
4, blood pressure detecting method
Non-invasivetesting instrument tail cover measuring blood pressure method.
5, statistical method
Data result represents with mean ± standard deviation (s), adopts the process of SPSS13.0 software statistics, adopts paired-samples T-test.
(3) experimental result
1, the comparative result of each treated animal patients before and after intervention blood pressure is in table 1:
The comparison (s) of table 1 each treated animal patients before and after intervention blood pressure
Group | n | Before administration (systolic pressure mmhg) | After administration (systolic pressure mmhg) | T value |
Blank group | 15 | 97.04±5.68 | 97.68±6.80 | -0.05 |
Model group | 15 | 97.64±5.78 | 98.72±5.14 | -0.11 |
Of the present invention group | 15 | 97.46±6.01 | 97.36±5.48 | -0.07 |
Positive controls | 15 | 97.43±5.29 | 97.45±6.82 | 0.06 |
As shown in table 1, after administration, difference of blood pressure not statistically significant between each group, illustrates medicine itself to animal used as test without impact.
2, before and after each treated animal modeling the comparative result of blood pressure in table 2:
The comparison (s) of blood pressure before and after each treated animal modeling of table 2
Group | n | Before modeling (systolic pressure mmhg) | After modeling (systolic pressure mmhg) | T value |
Blank group | 15 | 97.70±5.20 | 97.47±5.39 | 0.08 |
Model group | 15 | 96.08±5.40 | 135.20±8.43+++*** | 10.44 |
Of the present invention group | 15 | 97.60±5.61 | 118.47±7.87+++***### | 9.18 |
Positive controls | 15 | 97.65±5.75 | 120.37±9.62+++***### | 9.49 |
(+++: compare p < 0.001, * * * with before modeling and compare p < 0.001 with blank group; ### compares p < 0.001 with model group)
Shown in table 2, after modeling compared with before modeling, blank group blood pressure is without significant change, and there were significant differences for model group, of the present invention group and positive controls, and p < 0.001, illustrates that modeling successfully; Compare with blank group, all there were significant differences for model group, of the present invention group and positive control, p < 0.001, further illustrates modeling success; Compare with model group, all there were significant differences for of the present invention group and positive control, and p < 0.001, the effect that the present invention and kendir pressure-reducing sheet all have preventing hypertension to fall ill is described.
(4) experiment conclusion
Description of test the present invention significantly can control blood pressure and raise, and can fall ill by preventing hypertension, can be used for the health products preparing preventing hypertension.
Experimental example three safety testing
Acute toxicity test in mice: the feed adopting the product of embodiment of the present invention 1-3 to substitute mouse is completely fed, Continuous Observation 20 days, duration of test has no dead and undue toxicity reaction, off-test, Dissection test mouse, observe liver,kidney,spleen, stomach, the heart, lung and intestines, be showed no abnormal change.By standard of acute toxicity, this sample belongs to nontoxic level.
Chronic toxicity test: the feed adopting the product of embodiment of the present invention 1-3 to substitute mouse is completely fed, feed continuously 100 days, result shows: the mouse fur of the product of the embodiment of the present invention 1-3 that feeds is smooth, behavioral activity is normal, and drinking-water of ingesting is normal, and Normal-weight increases, blood parameters and hematology all fluctuate in normal range (NR), routine urinalysis and marrow index all fluctuate in normal range (NR), organize internal organs no abnormality seen, generally speaking have no toxicity reaction.
From testing above, product of the present invention is safe, nontoxic.
Be only specific embodiments of the invention above, but the present invention is not limited thereto, the changes that any person skilled in the art can think of, all should drops within protection scope of the present invention.
Claims (10)
1. health care's composition, it is characterized in that: by weight, be made up of following raw material: Poria cocos 800-1200 part, the root of straight ladybell 800-1200 part, radix polygonati officinalis 800-1200 part, lily 800-1200 part, Chinese yam 800-1200 part, Semen sesami nigrum 800-1200 part, French beans 800-1200 part, pinenut 400-600 part, matrimony vine 400-600 part, walnut 400-600 part.
2. a kind of health care's composition according to claim 1, it is characterized in that, be made up of following raw material: Poria cocos 900-1100 part, the root of straight ladybell 900-1100 part, radix polygonati officinalis 900-1100 part, lily 900-1100 part, Chinese yam 900-1100 part, Semen sesami nigrum 900-1100 part, French beans 900-1100 part, pinenut 450-550 part, matrimony vine 450-550 part, walnut 450-550 part.
3. a kind of health care's composition according to claim 1, it is characterized in that, be made up of following raw material: Poria cocos 950-1050 part, the root of straight ladybell 950-1050 part, radix polygonati officinalis 950-1050 part, lily 950-1050 part, Chinese yam 950-1050 part, Semen sesami nigrum 950-1050 part, French beans 950-1050 part, pinenut 475-525 part, matrimony vine 475-525 part, walnut 475-525 part.
4. a kind of health care's composition according to claim 1, it is characterized in that, be made up of following raw material: 1000 parts, Poria cocos, the root of straight ladybell 1000 parts, radix polygonati officinalis 1000 parts, lily 1000 parts, Chinese yam 1000 parts, Semen sesami nigrum 1000 parts, 1000 parts, French beans, pinenut 500 parts, matrimony vine 500 parts, walnut 500 parts.
5. a kind of health care's composition according to any one of claim 1-3, is characterized in that: described French beans are Semen Lablab Album.
6. a kind of health care's composition according to any one of claim 1-4, it is characterized in that, preparation method comprises the following steps:
1), get Poria cocos, the root of straight ladybell, radix polygonati officinalis, add 5-8 times amount soak by water 2-3 time, collecting decoction, filter, when filtrate being concentrated into 80 DEG C, relative density is 1.05 ~ 1.30, dry, pulverize, and obtains dried cream powder.
2), Semen Lablab Album is soaked in water 8-12h, and add 5-8 times amount soak by water 2-3h, at temperature 40 DEG C, forced air drying is≤5% to moisture, pulverizes as granule size is 90 object meal;
3), by yam slices, digestion 3-5min in boiling water, at temperature 40 DEG C, forced air drying to moisture is≤5%, pulverizes, obtains meal;
4), lily, Semen sesami nigrum, pinenut, matrimony vine, walnut coarse crushing under 0-(-4) DEG C condition, at temperature 40 DEG C, forced air drying to moisture is≤5%, at temperature 25 DEG C composition broken for granule size be 90 object meal;
5), by step 1) to 4) powder of gained and dried cream powder, use low temperature shock grinding machine, under-10 DEG C of conditions, vibrate 10min, being crushed to granule size is 800 object Ultramicro-powders; After mixing under 40 DEG C of conditions microwave disinfection 2h, add corresponding auxiliary material and be prepared as required product or direct packaging and get final product.
7. a kind of health care's composition according to claim 6, is characterized in that, step 2) in Semen Lablab Album soak before need to stir-fry at 70-80 DEG C 15 minutes cold removings.
8. a kind of health care's composition according to any one of claim 1-4, is characterized in that: described health care's composition can make health care's wheaten food or rice eats food or drink.
9. a kind of health care's composition according to any one of claim 1-4, is characterized in that: the preparation that described health care's composition is made is capsule, tablet, granule.
10. a kind of health care's composition according to any one of claim 1-4, is characterized in that: the application of described health care's composition in the health food or medicine of prevention conditioning hypertension, diabetes conditions.
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CN106261429A (en) * | 2016-08-31 | 2017-01-04 | 陈桂玲 | A kind of clear and rich beverage composition and preparation method thereof |
CN108522934A (en) * | 2018-05-09 | 2018-09-14 | 哈尔滨工业大学 | A kind of formula of the special Korean pine benevolence compound fatigue-resistant solid beverage of emergency disaster relief personnel |
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CN102845751A (en) * | 2012-09-21 | 2013-01-02 | 薛红云 | Food suitable for diabetic patients |
CN103251037A (en) * | 2012-02-15 | 2013-08-21 | 上海稻胜和实业发展有限公司 | Five-cereal nutritional powder able to reduce hyperlipemia, hypertension and hyperglycemia |
CN103504305A (en) * | 2013-10-28 | 2014-01-15 | 王伏春 | Health product with blood sugar reduction function and preparation method thereof |
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Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN103251037A (en) * | 2012-02-15 | 2013-08-21 | 上海稻胜和实业发展有限公司 | Five-cereal nutritional powder able to reduce hyperlipemia, hypertension and hyperglycemia |
CN102845751A (en) * | 2012-09-21 | 2013-01-02 | 薛红云 | Food suitable for diabetic patients |
CN103504305A (en) * | 2013-10-28 | 2014-01-15 | 王伏春 | Health product with blood sugar reduction function and preparation method thereof |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN106261429A (en) * | 2016-08-31 | 2017-01-04 | 陈桂玲 | A kind of clear and rich beverage composition and preparation method thereof |
CN108522934A (en) * | 2018-05-09 | 2018-09-14 | 哈尔滨工业大学 | A kind of formula of the special Korean pine benevolence compound fatigue-resistant solid beverage of emergency disaster relief personnel |
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