CN104341315A - 一种阿戈美拉汀晶型i的制备方法 - Google Patents
一种阿戈美拉汀晶型i的制备方法 Download PDFInfo
- Publication number
- CN104341315A CN104341315A CN201310345234.5A CN201310345234A CN104341315A CN 104341315 A CN104341315 A CN 104341315A CN 201310345234 A CN201310345234 A CN 201310345234A CN 104341315 A CN104341315 A CN 104341315A
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- CN
- China
- Prior art keywords
- organic solvent
- agomelatine
- aqueous solution
- ether
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- YJYPHIXNFHFHND-UHFFFAOYSA-N CC(NCCc1c(cc(cc2)OC)c2ccc1)=O Chemical compound CC(NCCc1c(cc(cc2)OC)c2ccc1)=O YJYPHIXNFHFHND-UHFFFAOYSA-N 0.000 description 1
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- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Battery Electrode And Active Subsutance (AREA)
Abstract
Description
2θ° | 相对强度[%] |
10.9 | 7.2 |
11.3 | 9.6 |
12.0 | 41.0 |
17.6 | 30.2 |
18.5 | 21.6 |
18.7 | 15.9 |
19.6 | 67.6 |
19.9 | 100.0 |
20.6 | 18.6 |
21.3 | 10.6 |
21.9 | 23.0 |
22.8 | 13.7 |
23.1 | 20.5 |
24.1 | 8.3 |
24.7 | 11.4 |
25.5 | 25.8 |
26.5 | 5.2 |
27.2 | 6.5 |
27.4 | 8.6 |
27.8 | 4.2 |
30.2 | 5.9 |
31.7 | 5.9 |
32.1 | 10.9 |
Claims (10)
Priority Applications (1)
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CN201310345234.5A CN104341315A (zh) | 2013-08-08 | 2013-08-08 | 一种阿戈美拉汀晶型i的制备方法 |
Applications Claiming Priority (1)
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CN201310345234.5A CN104341315A (zh) | 2013-08-08 | 2013-08-08 | 一种阿戈美拉汀晶型i的制备方法 |
Publications (1)
Publication Number | Publication Date |
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CN104341315A true CN104341315A (zh) | 2015-02-11 |
Family
ID=52497848
Family Applications (1)
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CN201310345234.5A Pending CN104341315A (zh) | 2013-08-08 | 2013-08-08 | 一种阿戈美拉汀晶型i的制备方法 |
Country Status (1)
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CN (1) | CN104341315A (zh) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102050755A (zh) * | 2009-10-29 | 2011-05-11 | 重庆医药工业研究院有限责任公司 | 阿戈美拉汀的新晶型及其制备方法 |
WO2011128413A1 (en) * | 2010-04-15 | 2011-10-20 | Ratiopharm Gmbh | Process for the production of polymorph form i of agomelatine |
CN102531942A (zh) * | 2011-11-17 | 2012-07-04 | 成都欣捷高新技术开发有限公司 | 一种阿戈美拉汀ⅰ晶型的制备方法 |
-
2013
- 2013-08-08 CN CN201310345234.5A patent/CN104341315A/zh active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102050755A (zh) * | 2009-10-29 | 2011-05-11 | 重庆医药工业研究院有限责任公司 | 阿戈美拉汀的新晶型及其制备方法 |
WO2011128413A1 (en) * | 2010-04-15 | 2011-10-20 | Ratiopharm Gmbh | Process for the production of polymorph form i of agomelatine |
CN102531942A (zh) * | 2011-11-17 | 2012-07-04 | 成都欣捷高新技术开发有限公司 | 一种阿戈美拉汀ⅰ晶型的制备方法 |
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CB03 | Change of inventor or designer information |
Inventor after: Fang Gan Inventor after: Wang Jubo Inventor after: Si Yongxing Inventor after: Xu Wei Inventor after: Gu Hong Inventor before: Fang Gan Inventor before: Wang Jubo Inventor before: Si Yongxing Inventor before: Xu Wei Inventor before: Wu Wenju Inventor before: Zhang Xini |
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Application publication date: 20150211 |
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RJ01 | Rejection of invention patent application after publication |