CN104323768B - A kind of parameter calibrating method of cardiac output continuous monitoring - Google Patents
A kind of parameter calibrating method of cardiac output continuous monitoring Download PDFInfo
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- CN104323768B CN104323768B CN201410550302.6A CN201410550302A CN104323768B CN 104323768 B CN104323768 B CN 104323768B CN 201410550302 A CN201410550302 A CN 201410550302A CN 104323768 B CN104323768 B CN 104323768B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/026—Measuring blood flow
- A61B5/029—Measuring or recording blood output from the heart, e.g. minute volume
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/026—Measuring blood flow
- A61B5/0275—Measuring blood flow using tracers, e.g. dye dilution
- A61B5/028—Measuring blood flow using tracers, e.g. dye dilution by thermo-dilution
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Abstract
The present invention relates to medical detection technology, and in particular to a kind of parameter calibrating method of cardiac output continuous monitoring.The present invention includes：Pulse wave data signal is measured by luminescent device；Meanwhile, the blood vessel of measured target, measurement standard cardiac output are accessed by conduit；Pulse wave data signal is calculated, RBF is obtained；And physiological models are set up according to the mapping relations；After physiological models are set up, the conduit connected with the blood vessel of measured target is withdrawn from, and the optical signal of two-way different wave length is continuously launched to the blood vessel of measured target by luminescent device, until obtaining continuous pulse wave data signal；Continuous pulse wave data signal is adjusted according to physiological models；The present invention need not it is long-term by catheter retention in patient body, therefore reduce the operation complexity of medical personnel, and reduce the pain of patient and potential injury.
Description
Technical field
The present invention relates to the technical field of medical treatment detection and parametric calibration, and in particular to a kind of cardiac output continuous monitoring
Parameter calibrating method.
Background technology
Cardiac output refers to the total blood volume that side ventricle per minute is projected, and is the product of heart rate and stroke output, is
The key clinical index of description cardiovascular system state.In clinic, especially intervene in operating room, ICU, heart or blood vessel
In treatment, cardiac output or stroke output can help medical personnel to know the heart body of patient, and to cardiac output
The continuous monitoring of change contribute to obtaining instant kinemic change, therefore to cardiac output or stroke output
Continuous monitoring is just particularly important with quick response.It is presently used for kinemic method for continuous measuring a lot, but it is existing
There is measuring method easily to be disturbed by various factors, the degree of accuracy is low, complex operation.
The content of the invention
To overcome drawbacks described above, the purpose of the present invention is to provide a kind of parametric calibration side of cardiac output continuous monitoring
Method.
The purpose of the present invention is achieved through the following technical solutions：
A kind of parameter calibrating method of kinemic continuous monitoring of the present invention, including：
The optical signal of two-way different wave length is launched by luminescent device to the blood vessel of measured target, is received through the blood vessel
Two ways of optical signals afterwards；Meanwhile, measurement standard cardiac output；The two ways of optical signals is converted to into corresponding electric signal, and is divided
Be not amplified two-way pulse wave data signal is obtained with process；
Two-way pulse wave data signal is calculated, the RBF of a cycle is obtained；
The mapping relations being calculated between standard cardiac output and RBF, and life is set up according to the mapping relations
Reason model；
After physiological models are set up, luminescent device is continued through continuously to the blood vessel transmitting two-way difference ripple of measured target
Long optical signal, until obtaining continuous pulse wave data signal.
Further, the mapping relations being calculated between standard cardiac output and RBF, and reflected according to this
The relation of penetrating sets up physiological models also to be included：
Mapping relations between calculating standard cardiac output and RBF, set up physiology mould according to the mapping relations
Type, and the physiological models are stored；
Judge whether to need to calculate mapping relations again, if desired calculate again, be then again introduced into the output of the measurement standard heart
The two ways of optical signals of amount and reception after the blood vessel；If need not calculate again, by all stored physiological models
Carry out averagely, and physiological models are updated according to average result.
Further, the luminescent device that continues through continuously launches the light of two-way different wave length to the blood vessel of measured target
Signal, includes after obtaining continuous pulse wave data signal：
The pulse frequency value obtained from continuous pulse wave data signal, and to adjustment after continuous pulse wave data signal
Calculate, obtain continuous RBF；
Continuous RBF is combined with physiological models, continuous stroke output is calculated；
Calculated with pulse frequency value using continuous stroke output, obtained continuous cardiac output.
Further, it is described obtain continuous cardiac output after include：
Continuous cardiac output is shown and/or is printed and/or stored.
Further, it is described obtain continuous cardiac output after include：
Judge continuous cardiac output whether within a predetermined range, it is if not within the predefined range, defeated to the continuous heart
Output is marked.
Further, the optical signal of the two-way different wave length includes：Red signal light and infrared signal.
The method of the present invention is, during kinemic continuous monitoring, to carry out school to the intermediate parameters of monitoring process
Accurate method；Standard cardiac output is measured, and RBF is gathered using photoelectric sensor, and it is defeated according to the standard heart
Mapping relations between output and RBF set up accurate physiological models, to realize the calibration of parameter so that the present invention
It is more accurate to kinemic monitoring result.
Description of the drawings
For ease of explanation, the present invention is described in detail by following preferred embodiments and accompanying drawing.
Fig. 1 is the workflow diagram of the parameter calibrating method of the kinemic continuous monitoring of the present invention；
Fig. 2 is the workflow continuously monitored using the parameter calibrating method of the kinemic continuous monitoring of the present invention
Cheng Tu；
Fig. 3 is the principle schematic diagram. of the kinemic continuous monitor system of the present invention.
Specific embodiment
In order that the objects, technical solutions and advantages of the present invention become more apparent, it is below in conjunction with drawings and Examples, right
The present invention is further elaborated.It should be appreciated that specific embodiment described herein is only to explain the present invention, and
It is not used in the restriction present invention.
Refer to Fig. 1, a kind of parameter calibrating method of kinemic continuous monitoring of the present invention, including：
101. connect photosignal
The optical signal of two-way different wave length is launched by luminescent device to the blood vessel of measured target, is received through the blood vessel
Two ways of optical signals afterwards, and the two ways of optical signals is converted to into corresponding electric signal I1、I2；
102. measurement standard cardiac outputs
103. obtain pulse wave data signal
Respectively electric signal is amplified two-way pulse wave data signal is obtained with process；
104. obtain RBF
Two-way pulse wave data signal is calculated, the RBF Q in a cardiac cycle is obtained；
105. set up physiological models
The mapping relations being calculated between standard cardiac output and RBF, and life is set up according to the mapping relations
Reason model；It is according to the present invention to be determined using mapping relations H through the arterial vascular RBF Q, i.e. Q=H
(I1、I2)；And due to there is corresponding relation between RBF Q and stroke output SV, therefore, it can obtain I1, I2With
Mapping relations J between SV, i.e.,：SV=J (I1、I2, μ), due to I1With I2The not only relevant information containing pulse wave, while
Also include the information of artery saturation degree, and therefore include total hemoglobin concentration and blood vessel diameter etc. information.In model
Calibration factor μ, between the RBF Q and stroke output SV in the arteries comprising privileged site ratio letter
Breath, while containing the ratio letter between the light path and arteries diameter caused when the diastole of arteries periodicity and contraction
Breath.For different patients, the concrete numerical value of μ is different, therefore, the factor mu in different patient models can be by calibration
Method obtain.Therefore, μ still can be calculated with RBF Q by standard cardiac output CO, to set up accurate physiology
Model.
106. continue continuous measurement pulse wave data signal
And the optical signal of two-way different wave length is continuously launched to the blood vessel of measured target by luminescent device, until obtaining
Continuous pulse wave data signal.
Fig. 2 is referred to, as a kind of extended mode, using the parametric calibration of the kinemic continuous monitoring of the present invention
Method carries out kinemic continuous monitoring, specifically includes：
201. connect photosignal
The optical signal of two-way different wave length is launched by luminescent device to the blood vessel of measured target, is received through the blood vessel
Two ways of optical signals afterwards, and the two ways of optical signals is converted to into corresponding electric signal；The optical signal of two-way different wave length is passed through
Generation two-way transmission or reflection optical signal after the blood vessel, blood vessel in the present invention are referred to and sufficiently close to human aortic
Artery, for example：Arteria carotis, axillary artery or femoral artery etc..As the arteries at these positions is not easy the shadow of the factors such as temperature
Ring and the change of generation vessel retraction or expansion.In physiological models according to the present invention, the arteries of selection is the closer to actively
Arteries and veins, the corresponding relation between its RBF and stroke output are more stable, and measurement result is more accurate.Due to physiological models
Relevant parameter is determined by calibration, therefore the privileged site pointed by the present invention, can be not limited to a certain fixed position,
Operator can select measuring point according to actual needs, increased the flexibility of operation so that operation is more easy.
In an embodiment of the present invention, arteria carotis is selected as the position for obtaining blood oxygen pulse wave signal.The position
It is nearer apart from sustainer, and the diastole shrinkage degree of blood vessel is more stable.
Wherein, the optical signal of two-way different wave length includes：Red signal light and infrared signal；
202. measurement standard cardiac outputs
Due to the individual difference of measured target, each not phase of the relevant parameter in the kinemic physiological models of continuous measurement
Together, therefore before continuously cardiac output is measured, need by accurate standard cardiac output measurement result at least one times
To calculate relevant parameter in the physiological models；
And as the kinemic method of existing measurement is varied, therefore the measurement standard heart pointed by the present invention is defeated
Output, can be not limited to the kinemic method of a certain particular measurement, and operator can according to actual needs and field condition
Proper calibration method is selected, the flexibility of operation is increased so that operation is more easy.
203. obtain pulse wave data signal
Respectively electric signal is amplified two-way pulse wave data signal is obtained with process；
204. obtain RBF
Two-way pulse wave data signal is calculated, the RBF 0 in a cardiac cycle is obtained；
205. set up physiological models
Mapping relations between calculating standard cardiac output and RBF, set up physiology mould according to the mapping relations
Type, and the physiological models are stored；
206. judge whether to need to calculate again
Judge whether to need to calculate mapping relations again, if desired calculate again, be then again introduced into the output of the measurement standard heart
The two ways of optical signals of amount and reception after the blood vessel；
207. update physiological models
If all stored physiological models are carried out averagely by judged result to calculate again, and according to flat
Equal result updates physiological models；
208. continue continuous measurement pulse wave data signal
And the optical signal of two-way different wave length is continuously launched to the blood vessel of measured target by luminescent device, until obtaining
Continuous pulse wave data signal；
The 209. pulse frequency values for obtaining
The pulse frequency value rule obtained from continuous pulse wave data signal,
210. obtain continuous RBF
To continuous pulse wave data signal of change, the RBF Q of continuous cycles is obtained；
211 calculate stroke output
Continuous RBF Q is combined with physiological models, continuous stroke output SV is calculated；
212. calculate continuous cardiac output
Calculated with pulse frequency value HR using continuous stroke output SV, obtained continuous cardiac output still, i.e. CO=
SV*HR；
The continuous cardiac output of 213. outputs
After continuous cardiac output CO is obtained, continuous cardiac output CO is shown and/or is printed and/or deposited
Storage；
The continuous cardiac output of 214. marks
After continuous cardiac output is obtained still, still whether within a predetermined range continuous cardiac output is judged, if not
Within a predetermined range, then mark is still provided for the continuous cardiac output.
Refer to Fig. 3, a kind of kinemic continuous monitor system of the present invention, including：
Photosignal sending and receiving module 301, the photosignal sending and receiving module 301 are attached on the blood vessel of measured target, are used
In the optical signal for launching two-way different wave length by luminescent device to the blood vessel of measured target, and receive after the blood vessel
The two ways of optical signals is converted to corresponding electric signal by two ways of optical signals；
Standard cardiac output measurement module 302, the standard cardiac output measurement module 302 are used to gather the output of the standard heart
Amount information, then standard cardiac output is calculated by standard cardiac output computer；And set up physiological models；
Pulse wave signal modular converter 303, the pulse wave signal modular converter 303 and photosignal sending and receiving module 301
Connection, for entering to two-way respectively, horizontal electrical signal amplifies and process obtains two-way pulse wave data signal；
RBF's computing module 304, RBF's computing module 304 and pulse wave signal modular converter
303 connections, for calculating to two-way pulse wave data signal, obtain RBF；
Physiological models creation module 305, the physiological models creation module 305 respectively with RBF's computing module
304 and standard cardiac output measurement module 302 connect, for according to RBF and standard cardiac output, calculating its mapping
Relation, and physiological models are set up according to the mapping relations；
Pulse frequency value acquisition module 307, the pulse frequency value acquisition module 307 are connected with pulse wave signal modular converter 303, are used
In the pulse frequency value obtained from pulse wave data signal；
Stroke output computing module 308, the stroke output computing module 308 and RBF's computing module
304 and physiological models creation module 305 connect, it is continuous for according to RBF after adjustment and physiological models, being calculated
Stroke output；
Continuous cardiac output computing module 306, the Continuous cardiac output computing module 306 calculate mould with stroke output
Block 308 and pulse frequency value acquisition module 307 connect, and for calculating with pulse frequency value to continuous stroke output, obtain continuous
Cardiac output.
Further, a kind of kinemic continuous monitor system of the present invention also includes：
Cardiac output display module, the cardiac output display module are connected with Continuous cardiac output computing module, are used for
Continuous cardiac output is shown；
Cardiac output print module, the cardiac output print module are connected with Continuous cardiac output computing module, are used for
Continuous cardiac output is printed；
Cardiac output memory module, the cardiac output memory module are connected with Continuous cardiac output computing module, are used for
Continuous cardiac output is stored；
Alarm module, the alarm module are connected with Continuous cardiac output computing module, for judging Continuous cardiac output
Whether within a predetermined range, if not within the predefined range, the continuous cardiac output is marked and alarm is carried out.
Further, the photosignal sending and receiving module includes：Red signal light receiving-transmitting device and infrared signal receiving-transmitting device.
Presently preferred embodiments of the present invention is the foregoing is only, not to limit the present invention, all essences in the present invention
Any modification, equivalent and improvement made within god and principle etc., should be included within the scope of the present invention.
Claims (5)
1. a kind of parameter calibrating method of cardiac output continuous monitoring, it is characterised in that include：
The optical signal of two-way different wave length is launched by luminescent device to the blood vessel of measured target, is received after the blood vessel
Two ways of optical signals；Measurement standard cardiac output；The two ways of optical signals is converted to into corresponding electric signal, and is amplified respectively
Two-way pulse wave data signal is obtained with process；
Two-way pulse wave data signal is calculated, the RBF of a cycle is obtained；
The mapping relations being calculated between standard cardiac output and RBF, and physiology mould is set up according to the mapping relations
Type；
After physiological models are set up, continue through luminescent device and continuously launch two-way different wave length to the blood vessel of measured target
Optical signal, until obtaining continuous pulse wave data signal；
The mapping relations being calculated between standard cardiac output and RBF, and life is set up according to the mapping relations
Reason model also includes：
Mapping relations between calculating standard cardiac output and RBF, set up physiological models according to the mapping relations, and
The physiological models are stored；
Judge whether to need to calculate mapping relations again, if desired calculate again, then be again introduced into measurement standard cardiac output and
Receive the two ways of optical signals after the blood vessel；If need not calculate again, all stored physiological models are carried out
Averagely, and according to average result physiological models are updated.
2. the parameter calibrating method of cardiac output continuous monitoring according to claim 1, it is characterised in that the continuation is led to
Cross luminescent device and continuously launch the optical signal of two-way different wave length to the blood vessel of measured target, until obtaining continuous pulse wave
Include after data-signal：
The pulse frequency value obtained from continuous pulse wave data signal, and to continuous pulse wave data signal of change, connected
The RBF in continuous cycle；
The RBF of continuous cycles is combined with physiological models, continuous stroke output is calculated；
Calculated with pulse frequency value using continuous stroke output, obtained continuous cardiac output.
3. the parameter calibrating method of cardiac output continuous monitoring according to claim 2, it is characterised in that described to be connected
Include after continuous cardiac output：
Continuous cardiac output is shown and/or is printed and/or stored.
4. the parameter calibrating method of cardiac output continuous monitoring according to claim 2, it is characterised in that described to be connected
Include after continuous cardiac output：
Judge continuous cardiac output whether within a predetermined range, if not within the predefined range, to the continuous cardiac output
It is marked.
5. the parameter calibrating method of the cardiac output continuous monitoring according to claim 3 or 4, it is characterised in that described two
The optical signal of road different wave length includes：Red signal light and infrared signal.
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| CN201410550302.6A CN104323768B (en) | 2012-11-20 | 2012-11-20 | A kind of parameter calibrating method of cardiac output continuous monitoring |
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|---|---|---|---|
| CN201410550302.6A CN104323768B (en) | 2012-11-20 | 2012-11-20 | A kind of parameter calibrating method of cardiac output continuous monitoring |
| CN201210471322.5A CN102908134B (en) | 2012-11-20 | 2012-11-20 | Parameter calibration method and parameter calibration system for continuously monitoring cardiac output |
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| CN201210471322.5A Division CN102908134B (en) | 2012-11-20 | 2012-11-20 | Parameter calibration method and parameter calibration system for continuously monitoring cardiac output |
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| CN104323768B true CN104323768B (en) | 2017-03-29 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105433936B (en) * | 2016-01-29 | 2018-06-05 | 北京心量科技有限公司 | Cardiac output preparation method and device |
| CN111493855B (en) * | 2020-04-21 | 2023-01-06 | 重庆理工大学 | System and method for non-invasive measurement of individualized cardiac output |
| CN116098601B (en) * | 2023-02-09 | 2023-09-19 | 山东埃尔法智慧医疗科技有限公司 | Verification method and equipment for noninvasive cardiac output parameters |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1231162A (en) * | 1998-03-31 | 1999-10-13 | 普尔松医疗***管理股份有限两合公司 | Device for in-vivo determination of compliance function and systemic blood flow of living being |
| US6736782B2 (en) * | 2001-03-01 | 2004-05-18 | Pulsion Medical Systems Ag | Apparatus, computer program, central venous catheter assembly and method for hemodynamic monitoring |
| EP2281504A1 (en) * | 2009-08-04 | 2011-02-09 | Pulsion Medical Systems AG | Apparatus and method for determining a physiological parameter |
| CN102008300A (en) * | 2010-12-10 | 2011-04-13 | 吉林大学 | Wearable multiple physiological parameter recording device |
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1231162A (en) * | 1998-03-31 | 1999-10-13 | 普尔松医疗***管理股份有限两合公司 | Device for in-vivo determination of compliance function and systemic blood flow of living being |
| US6736782B2 (en) * | 2001-03-01 | 2004-05-18 | Pulsion Medical Systems Ag | Apparatus, computer program, central venous catheter assembly and method for hemodynamic monitoring |
| EP2281504A1 (en) * | 2009-08-04 | 2011-02-09 | Pulsion Medical Systems AG | Apparatus and method for determining a physiological parameter |
| CN102008300A (en) * | 2010-12-10 | 2011-04-13 | 吉林大学 | Wearable multiple physiological parameter recording device |
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