CN104306761A - Granules for treating cold and preparation method thereof - Google Patents
Granules for treating cold and preparation method thereof Download PDFInfo
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- CN104306761A CN104306761A CN201410521462.8A CN201410521462A CN104306761A CN 104306761 A CN104306761 A CN 104306761A CN 201410521462 A CN201410521462 A CN 201410521462A CN 104306761 A CN104306761 A CN 104306761A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/413—Gall bladder; Bile
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
- A61K36/8888—Pinellia
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Abstract
The invention discloses granules for treating cold and a preparation method thereof. The granules for treating cold are prepared from the following raw materials in parts by weight: 30-40 parts of lemongrass, 12-18 parts of liquorice, 5-10 parts of honeysuckle, 10-18 parts of dried tangerine or orange peel, 6-9 parts of bezoar and 5-10 parts of pinellia ternate. The preparation method comprises the following steps: 1, washing and cleaning fresh lemongrass, liquorice, honeysuckle and pinellia ternate and carrying out fixation treatment; 2, separately mechanically grinding lemongrass, liquorice, honeysuckle, dried tangerine or orange peel, bezoar and pinellia ternate and sieving, then weighing according to the requirement and homogenizing to obtain a mixture; and 3, sterilizing the mixture and subpackaging to obtain the granules for treating cold. The preparation method is simple and low in cost; the prepared granules have a remarkable treatment effect on cold, are stable in efficacy and are suitable for mass production.
Description
Technical field
The present invention relates to coldrex field, be specifically related to a kind of GANMAO CHONGJI and preparation method thereof.
Background technology
Flu is a kind of commonly encountered diseases, is divided into common cold and influenza generally.Common cold, the traditional Chinese medical science claims " cold ", how to be caused by Respirovirus, and be wherein main virus with coronavirus and rhinovirus, clinical manifestation is its feature mainly with nasal obstruction, watery nasal discharge, cough, headache, aversion to cold etc., all can fall ill the whole year, especially common with spring.Influenza is the Acute respiratory infectious disease caused by influenza virus.In addition, flu is a kind of self-healing property disease, and the course of disease is generally seven days, and therefore, the quality of coldrex curative effect, is embodied in its onset speed to a great extent.
The medicine of present treatment flu mostly is Western medicine, cures the symptoms, not the disease, and the limited efficiency for the treatment of, and after drug administration, have lethargy, the side effect such as listless, irritated, and price is more expensive.
A lot of research shows that Chinese medicine is in treatment viral disease than Western medicine advantageously, and theory of Chinese medical science is thought: catch a cold caused by being invaded by exogenous pathogen, the disease being located in the exterior, belongs to the sign of the traditional Chinese medical science, treats appropriate to the occasionly to disperse its table, it is generally acknowledged disease Shang Biao person, should relieving the exterior syndrome by diaphoresis eliminating evil.The Chinese medicine cold-treating preparation that current pharmaceutical factory produces, mostly be cool cold medicine, based on heat-clearing and toxic substances removing, this Chinese medicine cold-treating preparation is only applicable to the middle and advanced stage of anemopyretic cold or anemofrigid cold and has entered other diseases that inner heat-transformation becomes raw, its onset is slow, in body, good and evil hand over the time of striving long, and after healing, vapour losses is many, namely immunity, resistance decline, cause physical weakness, easily infect other disease, still lack Chinese medicine cold-treating preparation that is effective, rapid-action, that have no side effect in the market.
Application number be 201210572734.8 China application discloses that a kind of Chinese medicine preparation for the treatment of flu, this Chinese medicine preparation is mixed by Flos Lonicerae, Radix Bupleuri, artificial Calculus Bovis, Radix Puerariae, Radix Glycyrrhizae, Fructus Arctii, the Radix Astragali, Pheretima, Herba Houttuyniae, Folium Perillae, Herba Asari, Flos Magnoliae, Herba Menthae and Gypsum Fibrosum.Application number be 201110167907.3 China application discloses that a kind of instant particles as Chinese medicine for the treatment of flu, this instant particles as Chinese medicine is mixed by Folium Perillae, Semen Armeniacae Amarum, Radix Peucedani, Pericarpium Citri Reticulatae, Rhizoma Atractylodis, Radix Glycyrrhizae, Calculus Bovis and Fructus Forsythiae.Although these two inventions all select taste of Chinese medicine raw material to prepare GANMAO CHONGJI, Chinese medicine kind is more, has certain zest to infant, in addition, these two kinds of electuary onset times are longer, and taste is partially bitter, adult takes and is difficult to accept, to child's medicine feed trouble especially.
Summary of the invention
For the deficiencies in the prior art, the object of the present invention is to provide a kind of GANMAO CHONGJI and preparation method thereof, its instant effect, cost is low.
A kind of GANMAO CHONGJI, comprises the following raw material counted by weight: Herba Cymbopogonis Citrari 30-40 part, Radix Glycyrrhizae 12-18 part, Flos Lonicerae 5-10 part, Pericarpium Citri Reticulatae 10-18 part, Calculus Bovis 6-9 part, Rhizoma Pinelliae 5-10 part.
As preferably, above-mentioned GANMAO CHONGJI, comprises the following raw material counted by weight: Herba Cymbopogonis Citrari 34-38 part, Radix Glycyrrhizae 14-16 part, Flos Lonicerae 7-8 part, Pericarpium Citri Reticulatae 15-18 part, Calculus Bovis 7-8 part, Rhizoma Pinelliae 6-8 part.
As preferably, above-mentioned GANMAO CHONGJI, Herba Cymbopogonis Citrari 35 parts, 15 parts, Radix Glycyrrhizae, Flos Lonicerae 8 parts, Pericarpium Citri Reticulatae 16 parts, Calculus Bovis 7 parts, the Rhizoma Pinelliae 8 parts.
The preparation method of above-mentioned GANMAO CHONGJI, comprises the following steps:
Step one, get fresh Herba Cymbopogonis Citrari, Radix Glycyrrhizae, Flos Lonicerae and the Rhizoma Pinelliae and clean, complete process;
Step 2, grinds Herba Cymbopogonis Citrari, Radix Glycyrrhizae, Flos Lonicerae, Pericarpium Citri Reticulatae, Calculus Bovis and the Rhizoma Pinelliae with machinery respectively and sieves, take required weight, obtains mixture after homogenizing process;
Step 3, obtains GANMAO CHONGJI by subpackage after mixture sterilization.
As preferably, in the preparation method of above-mentioned GANMAO CHONGJI, the treatment temperature that completes of step one is 105 DEG C.
As preferably, in the preparation method of above-mentioned GANMAO CHONGJI, the Herba Cymbopogonis Citrari of step 2, Radix Glycyrrhizae, Flos Lonicerae, Pericarpium Citri Reticulatae, Calculus Bovis and Rhizoma Pinelliae machinery grind the order number sieved and are 400 orders.
As preferably, in the preparation method of above-mentioned GANMAO CHONGJI, the sterilization of step 3 adopts pasteurization.
As preferably, in the preparation method of above-mentioned GANMAO CHONGJI, the subpackage specification of step 3 is 25g/ bag.
Pharmacology of the present invention is as follows:
Herba Cymbopogonis Citrari: chemical composition is that herb contains acid saponins, tannin, protein, phlegmatic temperament, amaroid, saccharide and phenolic substance.Fresh grass is containing volatile oil 0.7-1.O%, and leaf is containing volatile oil about 1.8%, and floral axis about 0.5%, stem is less than 0.05%.Containing piperitone 40-50%, carene-4 20%, Geraniol 10%, Mang Ethylgeranate 10% in volatile oil, still there are Mang geranial, limonene etc.Also containing anisaldehyde and alpha-terpineol, 2R-(2 α, 4a β, 8 α, 8a α)-decahydro-8 Alpha-hydroxy-α, α, 4a, 8-tetramethyl-2-naphthalene methanol, there is relieving cough and asthma, antibacterial effect.
Radix Glycyrrhizae: sweet, flat, invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
Flos Lonicerae: sweet, cold, return lung, the heart, stomach warp, there is heat-clearing and toxic substances removing, effect of wind-heat dissipating, sore throat, erysipelas, toxic-heat and blood stasis, flu, epidemic febrile disease heating etc. can be treated.
Pericarpium Citri Reticulatae: regulating qi-flowing for strengthening spleen, in tune, dampness, reduces phlegm.Cure mainly distension and fullness in the abdomen or pain, the dyspepsia of stagnation of QI in spleen and stomach.Abdominal distention uncomfortable in chest in turbid damp resistance, indigestion and loss of appetite loose stool.
Calculus Bovis: bitter cold, has heat-clearing and toxic substances removing, the function of dispelling phlegm and relieving sore-throat, is usually used in the symptoms such as calentura heating, laryngopharynx swelling and pain.
The Rhizoma Pinelliae: Araeceae Pinellia Tenore is a kind of, herbaceos perennial.The Rhizoma Pinelliae cry again water beautiful, literary composition and aunt, evil field, show aunt, the sheep eye Rhizoma Pinelliae, the pearl Rhizoma Pinelliae, numb taro fruit, three step jumpings, general stone, old shaven head, crow head, Fructus Crotonis, be not in the mood for dish root, corbie eye, Thunder God, Canis familiaris L. Fructus Colocasiae Esculentae.Herbaceos perennial, high 15 ~ 30 centimetres.5 ~ July of florescence.Fruit phase 8 ~ JIUYUE.In the wild thick grass dark and damp in hillside, small stream limit or sylvan life, leaf has long handle, opens yellow green flower early summer.Underground adularescent tubercle, can be used as medicine.There is distribution in most of China area, has effect of antitussive and expectorant.
beneficial effect
Compared with prior art, the present invention adopts Herba Cymbopogonis Citrari and the Rhizoma Pinelliae to be Chinese medicine GANMAO CHONGJI prepared by raw material, has removing heat from blood sore-throat relieving, heat-clearing and toxic substances removing, relieving cough and resolving phlegm, and the onset for the treatment of flu is rapid, evident in efficacy, Herba Cymbopogonis Citrari cheap, greatly reduces the cost of electuary.In addition, Herba Cymbopogonis Citrari has dense lemon, the electuary made does not need to add any essence, hides and the taste of other medical materials, is conducive to the resisting psychology eliminating patient consumes, is especially applicable to infant taking.
Detailed description of the invention
The following examples can make the present invention of those skilled in the art comprehend, but do not limit the present invention in any way.
Embodiment 1
A kind of GANMAO CHONGJI, comprises the following raw material counted by weight: Herba Cymbopogonis Citrari 30 parts, 12 parts, Radix Glycyrrhizae, Flos Lonicerae 5 parts, Pericarpium Citri Reticulatae 10 parts, Calculus Bovis 6 parts, the Rhizoma Pinelliae 5 parts.
The preparation method of above-mentioned GANMAO CHONGJI, comprises the following steps:
Step one, gets fresh Herba Cymbopogonis Citrari, Radix Glycyrrhizae, Flos Lonicerae and the Rhizoma Pinelliae and cleans, 105 DEG C of process that complete;
Step 2, uses milled 400 mesh sieves of machinery respectively, takes required weight, obtain mixture after homogenizing process by Herba Cymbopogonis Citrari, Radix Glycyrrhizae, Flos Lonicerae, Pericarpium Citri Reticulatae, Calculus Bovis and the Rhizoma Pinelliae;
Step 3, obtains GANMAO CHONGJI according to the specification subpackage of 25g/ bag after being sterilized by mixture pasteurization.
Embodiment 2
A kind of GANMAO CHONGJI, comprises the following raw material counted by weight: Herba Cymbopogonis Citrari 32 parts, 14 parts, Radix Glycyrrhizae, Flos Lonicerae 7 parts, Pericarpium Citri Reticulatae 12 parts, Calculus Bovis 7 parts, the Rhizoma Pinelliae 6 parts.
The preparation method of above-mentioned GANMAO CHONGJI, comprises the following steps:
Step one, gets fresh Herba Cymbopogonis Citrari, Radix Glycyrrhizae, Flos Lonicerae and the Rhizoma Pinelliae and cleans, 105 DEG C of process that complete;
Step 2, uses milled 200 mesh sieves of machinery respectively, takes required weight, obtain mixture after homogenizing process by Herba Cymbopogonis Citrari, Radix Glycyrrhizae, Flos Lonicerae, Pericarpium Citri Reticulatae, Calculus Bovis and the Rhizoma Pinelliae;
Step 3, obtains GANMAO CHONGJI according to 20g/ bag subpackage after being sterilized by mixture pasteurization.
Embodiment 3
A kind of GANMAO CHONGJI, comprises the following raw material counted by weight: Herba Cymbopogonis Citrari 35 parts, 15 parts, Radix Glycyrrhizae, Flos Lonicerae 8 parts, Pericarpium Citri Reticulatae 16 parts, Calculus Bovis 7 parts, the Rhizoma Pinelliae 8 parts.
The preparation method of above-mentioned GANMAO CHONGJI, comprises the following steps:
Step one, gets fresh Herba Cymbopogonis Citrari, Radix Glycyrrhizae, Flos Lonicerae and the Rhizoma Pinelliae and cleans, 105 DEG C of process that complete;
Step 2, uses milled 400 mesh sieves of machinery respectively, takes required weight, obtain mixture after homogenizing process by Herba Cymbopogonis Citrari, Radix Glycyrrhizae, Flos Lonicerae, Pericarpium Citri Reticulatae, Calculus Bovis and the Rhizoma Pinelliae;
Step 3, obtains GANMAO CHONGJI according to the specification subpackage of 25g/ bag after being sterilized by mixture pasteurization.
Embodiment 4
A kind of GANMAO CHONGJI, comprises the following raw material counted by weight: Herba Cymbopogonis Citrari 38 parts, 16 parts, Radix Glycyrrhizae, Flos Lonicerae 9 parts, Pericarpium Citri Reticulatae 16 parts, Calculus Bovis 8 parts, the Rhizoma Pinelliae 8 parts.
The preparation method of above-mentioned GANMAO CHONGJI, comprises the following steps:
Step one, gets fresh Herba Cymbopogonis Citrari, Radix Glycyrrhizae, Flos Lonicerae and the Rhizoma Pinelliae and cleans, 105 DEG C of process that complete;
Step 2, uses milled 300 mesh sieves of machinery respectively, takes required weight, obtain mixture after homogenizing process by Herba Cymbopogonis Citrari, Radix Glycyrrhizae, Flos Lonicerae, Pericarpium Citri Reticulatae, Calculus Bovis and the Rhizoma Pinelliae;
Step 3, obtains GANMAO CHONGJI according to 25g/ bag subpackage after being sterilized by mixture pasteurization.
Embodiment 5
A kind of GANMAO CHONGJI, comprises the following raw material counted by weight: Herba Cymbopogonis Citrari 40 parts, 18 parts, Radix Glycyrrhizae, Flos Lonicerae 0 part, Pericarpium Citri Reticulatae 18 parts, Calculus Bovis 9 parts, the Rhizoma Pinelliae 10 parts.
The preparation method of above-mentioned GANMAO CHONGJI, comprises the following steps:
Step one, gets fresh Herba Cymbopogonis Citrari, Radix Glycyrrhizae, Flos Lonicerae and the Rhizoma Pinelliae and cleans, 105 DEG C of process that complete;
Step 2, uses milled 400 mesh sieves of machinery respectively, takes required weight, obtain mixture after homogenizing process by Herba Cymbopogonis Citrari, Radix Glycyrrhizae, Flos Lonicerae, Pericarpium Citri Reticulatae, Calculus Bovis and the Rhizoma Pinelliae;
Step 3, obtains GANMAO CHONGJI according to the specification subpackage of 25g/ bag after being sterilized by mixture pasteurization.
Choose 600 cold patients for tested object, be divided into 2 groups, often group comprises male, women and child and accounts for 100, by the GANMAO CHONGJI prepared with the present invention with now use GANMAO CHONGJI (as a comparison case) to treat, records cure time as shown in table 1.
Table 1 patient fully recovers situation catalog
From the results shown in Table 1, GANMAO CHONGJI of the present invention, rapid-action, patient acceptance is high, and especially in cough-relieving, curative effect is more obviously good, reduces because cough other complication brought.
Claims (8)
1. a GANMAO CHONGJI, is characterized in that, comprises the following raw material counted by weight: Herba Cymbopogonis Citrari 30-40 part, Radix Glycyrrhizae 12-18 part, Flos Lonicerae 5-10 part, Pericarpium Citri Reticulatae 10-18 part, Calculus Bovis 6-9 part, Rhizoma Pinelliae 5-10 part.
2. GANMAO CHONGJI according to claim 1, is characterized in that, comprises the following raw material counted by weight: Herba Cymbopogonis Citrari 34-38 part, Radix Glycyrrhizae 14-16 part, Flos Lonicerae 7-8 part, Pericarpium Citri Reticulatae 15-18 part, Calculus Bovis 7-8 part, Rhizoma Pinelliae 6-8 part.
3. GANMAO CHONGJI according to claim 1, is characterized in that, comprises the following raw material counted by weight: Herba Cymbopogonis Citrari 35 parts, 15 parts, Radix Glycyrrhizae, Flos Lonicerae 8 parts, Pericarpium Citri Reticulatae 16 parts, Calculus Bovis 7 parts, the Rhizoma Pinelliae 8 parts.
4. the preparation method of GANMAO CHONGJI according to claim 1, is characterized in that, comprises the following steps:
Step one, get fresh Herba Cymbopogonis Citrari, Radix Glycyrrhizae, Flos Lonicerae and the Rhizoma Pinelliae and clean, complete process;
Step 2, grinds Herba Cymbopogonis Citrari, Radix Glycyrrhizae, Flos Lonicerae, Pericarpium Citri Reticulatae, Calculus Bovis and the Rhizoma Pinelliae with machinery respectively and sieves, take required weight, obtains mixture after homogenizing process;
Step 3, obtains GANMAO CHONGJI by subpackage after mixture sterilization.
5. the preparation method of GANMAO CHONGJI according to claim 4, is characterized in that: the treatment temperature that completes of step one is 105 DEG C.
6. the preparation method of GANMAO CHONGJI according to claim 4, is characterized in that: the Herba Cymbopogonis Citrari of step 2, Radix Glycyrrhizae, Flos Lonicerae, Pericarpium Citri Reticulatae, Calculus Bovis and Rhizoma Pinelliae machinery grind the order number sieved and is 400 orders.
7. the preparation method of GANMAO CHONGJI according to claim 4, is characterized in that: the sterilization of step 3 adopts pasteurization.
8. the preparation method of GANMAO CHONGJI according to claim 4, is characterized in that: the subpackage specification of step 3 is 25g/ bag.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201410521462.8A CN104306761A (en) | 2014-09-30 | 2014-09-30 | Granules for treating cold and preparation method thereof |
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| CN201410521462.8A CN104306761A (en) | 2014-09-30 | 2014-09-30 | Granules for treating cold and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107495046A (en) * | 2017-10-09 | 2017-12-22 | 南京图艾生物医药科技有限公司 | A kind of wheat germ polypeptide health care drink |
| CN107929461A (en) * | 2017-12-15 | 2018-04-20 | 苏州科技城医院 | Treat Chinese medicine preparation, oral liquid of children's pyretic cold and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102430107A (en) * | 2011-12-14 | 2012-05-02 | 钟跃平 | Medicinal granules for treating cold and preparation method thereof |
| WO2014063282A1 (en) * | 2012-10-22 | 2014-05-01 | Jiang Tingyi | Chinese medicine for treatment of common cold and preparation method |
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2014
- 2014-09-30 CN CN201410521462.8A patent/CN104306761A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102430107A (en) * | 2011-12-14 | 2012-05-02 | 钟跃平 | Medicinal granules for treating cold and preparation method thereof |
| WO2014063282A1 (en) * | 2012-10-22 | 2014-05-01 | Jiang Tingyi | Chinese medicine for treatment of common cold and preparation method |
Non-Patent Citations (2)
| Title |
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| 段金廒等: "药材初加工"杀青"环节与药材品质形成的探讨", 《中药材》 * |
| 詹文涛: "《临床常用中草药》", 31 October 1996, 云南科技出版社 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107495046A (en) * | 2017-10-09 | 2017-12-22 | 南京图艾生物医药科技有限公司 | A kind of wheat germ polypeptide health care drink |
| CN107929461A (en) * | 2017-12-15 | 2018-04-20 | 苏州科技城医院 | Treat Chinese medicine preparation, oral liquid of children's pyretic cold and preparation method thereof |
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