CN104306166A - Salicylic acid microcapsule, preparation method and skin-protecting cream thereof - Google Patents
Salicylic acid microcapsule, preparation method and skin-protecting cream thereof Download PDFInfo
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- CN104306166A CN104306166A CN201410563809.5A CN201410563809A CN104306166A CN 104306166 A CN104306166 A CN 104306166A CN 201410563809 A CN201410563809 A CN 201410563809A CN 104306166 A CN104306166 A CN 104306166A
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- salicylic acid
- microcapsule
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Abstract
The invention discloses a salicylic acid microcapsule, a preparation method and skin-protecting cream thereof. The salicylic acid microcapsule is prepared from a core material and a wall material in a mass ratio of (10:1)-(5:2). The skin-protecting cream is capable of effectively playing effects of salicylic acid in removing cutin, controlling oil, inhibiting bacteria, protecting skin and reducing intense irritation of salicylic acid on skin, so that the effect of sustainably releasing salicylic acid can be achieved, and the safety stability of salicylic acid can be improved.
Description
Technical field
The invention belongs to cosmetic field, specifically, relate to a kind of salicylic acid microcapsule and preparation method thereof and cold cream frost.
Background technology
Salicylic acid is beta-hydroxy acid (Beta Hydroxy Acid), also known as the soft skin fruit acid of BHA, B, is present in natural bark of willow, Gaultheria leaf and sweet birch tree.Salicylic acid has and dissolves the excess oil of facial pores and always dead and impaired horn cell, the effect of suppression sebum secretion and bacteria breed, the effect such as aging can also desalinated pigmented spots, reduce pore, remove fine wrinkles and improve that Exposure to Sunlight causes.But salicylic acid is insoluble in water and has comparatively strong and stimulating, thus its application is very limited.And the salicylic acid adopting microcapsule technology to wrap up, the original zest of salicylic acid can be reduced, make it while performance effect, effect milder.
Summary of the invention
The object of the invention is to overcome the deficiencies in the prior art, while providing a kind of three kinds of bacterium that can effectively suppress to cause acne to occur to produce, reduce salicylic acid to the salicylic acid microcapsule of skin intense stimulus and cold cream frost thereof.
To achieve these goals, present invention employs following technical scheme:
A kind of salicylic acid microcapsule, be made up of wall material and core, its mass ratio is 10:1 ~ 5:2.
In above-mentioned salicylic acid microcapsule, the mass ratio of described wall material and core is preferably 5:1.
In above-mentioned salicylic acid microcapsule, described core is salicylic acid; Described wall material is made up of the component of following weight portion: starch sodium octenyl succinate 30-60 part, beta cyclodextrin 30-60 part, maltodextrin 5-40 part.
In above-mentioned salicylic acid microcapsule, described wall material is preferably made up of the component of following weight portion: starch sodium octenyl succinate 40-45 part, beta cyclodextrin 40-45 part, maltodextrin 15-20 part.
The preparation method of above-mentioned salicylic acid microcapsule, comprises the steps: wall material and core to carry out to mix, stirs, homogenizing, forms through spraying dry.
A cold cream frost, be made up of salicylic acid microcapsule and adjuvant, the percetage by weight of salicylic acid microcapsule and substrate adjuvant is respectively 1-8%, 92-99%.According to the change of cream frost substrate adjunct ingredient, and the difference of salicylic acid microcapsule addition, cold cream frost comprises: exfoliation frost, acne eliminating cream, massage cream, Whelk-eliminating paste etc.
Compared with prior art, the present invention has following beneficial effect: salicylic acid microcapsule prepared by the present invention, can reduce the original zest of salicylic acid, makes it while performance effect, effect milder.Cold cream frost of the present invention reduces salicylic acid to skin strong impulse while effectively suppressing the three kinds of bacterium causing acne to occur to produce, and reaches salicylic slow release effect and improves salicylic acid stability.
Detailed description of the invention
Below by way of specific embodiment, the present invention is further illustrated, but these embodiments are just in order to illustrate, are not limitations of the present invention.
Embodiment 1 exfoliation frost
Get salicylic acid 40g and wall material 100g (by starch sodium octenyl succinate 60g, beta cyclodextrin 30g and maltodextrin 10g forms wall material).Salicylic acid and wall material carried out mix, stir, homogenizing, through spraying dry salicylic acid microcapsule.
Stearic acid 14.0; Lanoline 4.0; Mineral oil 28.0; Aluminosilicate magnesium 5.0; Triethanolamine 3.0; Glycerol 5.0; Salicylic acid microcapsule 2.0; Essence antiseptic 2.0; Water surplus; Obtained exfoliation frost.(each material % by weight, summation is 100%).
Embodiment 2 acne eliminating cream
Get salicylic acid 30g and wall material 100g (by starch sodium octenyl succinate 50g, beta cyclodextrin 35g and maltodextrin 15g forms wall material).Salicylic acid and wall material carried out mix, stir, homogenizing, through spraying dry salicylic acid microcapsule.
Polyoxyethylene hydrogenated Oleum Ricini 3.0; Stearic acid monoglycerides 3.0; Olive oil 1.0; Methyl parahydroxybenzoate 0.2; Stearic acid 3.0; Myristic acid 3.0; Salicylic acid microcapsule 4.0; Essence 2.0; Water surplus; Obtained acne eliminating cream (each material % by weight, summation is 100%).
Embodiment 3 massage cream
Get salicylic acid 20g and wall material 100g (by starch sodium octenyl succinate 40g, beta cyclodextrin 40g and maltodextrin 20g forms wall material).Salicylic acid and wall material carried out mix, stir, homogenizing, through spraying dry salicylic acid microcapsule.
Lanoline 3.0; Squalane 8.0; Ester 2.0 gone alone by stearic acid; Hexadeca-octadecyl alcohol ether 1.0; Stearic acid 2.5; Octyl hydroxystearate; Hexadeca-octadecyl alcohol 2.0; Glycerol 3.0; Carbopol 940 0.24; Triethanolamine (regulating pH to 6.5 ~ 7.0); Salicylic acid microcapsule 6.0; Water surplus; Obtained massage cream (each material % by weight, summation is 100%).
Embodiment 4 Whelk-eliminating paste
Get salicylic acid 10g and wall material 100g (by starch sodium octenyl succinate 30g, beta cyclodextrin 55g and maltodextrin 15g forms wall material).Salicylic acid and wall material carried out mix, stir, homogenizing, through spraying dry salicylic acid microcapsule.
Stearic acid 4.0; White mineral oil 5.0; Ester 1.0 gone alone by stearic acid; Glycerol monohydroxy stearate 2.0; Hexadeca-octadecyl alcohol 3.0; Hexadecanol caprylate 10.0; Glycerol 3.0; 2% card ripple 94110.0; Triethanolamine 1.5; Salicylic acid microcapsule 8.0; Essence antiseptic 2.0; Water surplus; Obtained Whelk-eliminating paste (each material % by weight, summation is 100%).
Embodiment 5 cold cream frost bacteriostatic experiment
To be used for staphylococcus aureus containing salicylic acid microcapsule acne eliminating cream, the bacteriostatic experiment of staphylococcus epidermidis and propionibacterium acnes three kinds of pathogenic bacterias, experimental result is in table 1.
Salicylic acid, salicylic acid microcapsule and the bacteriostatic test containing salicylic acid microcapsule cream frost the results are shown in Table 1.As seen from the table, salicylic acid itself has biocidal property, and salicylic acid microcapsule joins in cream still has biocidal property to three kinds of antibacterials.
Table 1. salicylic acid microcapsule acne eliminating cream is to the inhibition zone result of 3 kinds of acne pathogenic bacterium
Note: "-" represents insensitive, antibacterial circle diameter < 7mm; "+" represents responsive, antibacterial circle diameter 7 ~ 10mm; " ++ " represents responsive, antibacterial circle diameter 10 ~ 15mm..
Claims (6)
1. a salicylic acid microcapsule, is made up of wall material and core, and its mass ratio is 10:1 ~ 5:2.
2. salicylic acid microcapsule as claimed in claim 1, it is characterized in that, the mass ratio of described wall material and core is 5:1.
3. salicylic acid microcapsule as claimed in claim 1, it is characterized in that, described core is salicylic acid; Described wall material is made up of the component of following weight portion: starch sodium octenyl succinate 30-60 part, beta cyclodextrin 30-60 part, maltodextrin 5-40 part.
4. salicylic acid microcapsule as claimed in claim 3, it is characterized in that, described wall material is made up of the component of following weight portion: starch sodium octenyl succinate 40-45 part, beta cyclodextrin 40-45 part, maltodextrin 15-20 part.
5. the preparation method of salicylic acid microcapsule described in claim 1, is characterized in that comprising the steps: wall material and core being carried out mixing, stirs, homogenizing, forms through spraying dry.
6. a cold cream frost, it is characterized in that being made up of salicylic acid microcapsule and substrate adjuvant, the percetage by weight of salicylic acid microcapsule and adjuvant is respectively 1-8%, 92-99%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410563809.5A CN104306166B (en) | 2014-10-21 | 2014-10-21 | A kind of salicylic acid microcapsules and preparation method thereof and skin care cream |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410563809.5A CN104306166B (en) | 2014-10-21 | 2014-10-21 | A kind of salicylic acid microcapsules and preparation method thereof and skin care cream |
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| CN104306166A true CN104306166A (en) | 2015-01-28 |
| CN104306166B CN104306166B (en) | 2018-01-26 |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106913471A (en) * | 2017-03-10 | 2017-07-04 | 佛山市禅香新材料有限公司 | A kind of salicylic acid solid microcapsules and preparation method thereof |
| CN107595655A (en) * | 2017-10-10 | 2018-01-19 | 上海格兰化妆品有限公司 | A kind of salicylic drug-loading system and its preparation method and application |
| CN108210346A (en) * | 2018-01-10 | 2018-06-29 | 上海应用技术大学 | It is a kind of to load salicylic compound wall materials microcapsules and preparation method thereof |
| CN108652009A (en) * | 2018-05-18 | 2018-10-16 | 南昌大学 | A kind of preparation method of sustained release digestion fish oil micro-capsule |
| CN108852913A (en) * | 2018-09-27 | 2018-11-23 | 上海应用技术大学 | A kind of facial cleanser and preparation method thereof comprising salicylic acid microcapsules |
| CN109054000A (en) * | 2018-07-24 | 2018-12-21 | 中山大学 | A kind of nanometer medicine-carried system and its preparation method and application based on polysalicylates acid |
| CN111150674A (en) * | 2020-03-02 | 2020-05-15 | 上海新高姿化妆品有限公司 | Acne removing composition with mild oil control function and preparation method thereof |
| CN113101375A (en) * | 2021-05-08 | 2021-07-13 | 惠州市绿亚生物材料有限公司 | Chitosan grafted salicylic acid microcapsule and preparation method thereof |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106913471A (en) * | 2017-03-10 | 2017-07-04 | 佛山市禅香新材料有限公司 | A kind of salicylic acid solid microcapsules and preparation method thereof |
| CN107595655A (en) * | 2017-10-10 | 2018-01-19 | 上海格兰化妆品有限公司 | A kind of salicylic drug-loading system and its preparation method and application |
| CN108210346A (en) * | 2018-01-10 | 2018-06-29 | 上海应用技术大学 | It is a kind of to load salicylic compound wall materials microcapsules and preparation method thereof |
| CN108210346B (en) * | 2018-01-10 | 2020-06-23 | 上海应用技术大学 | Composite wall material microcapsule loaded with salicylic acid and preparation method thereof |
| CN108652009A (en) * | 2018-05-18 | 2018-10-16 | 南昌大学 | A kind of preparation method of sustained release digestion fish oil micro-capsule |
| CN109054000A (en) * | 2018-07-24 | 2018-12-21 | 中山大学 | A kind of nanometer medicine-carried system and its preparation method and application based on polysalicylates acid |
| CN108852913A (en) * | 2018-09-27 | 2018-11-23 | 上海应用技术大学 | A kind of facial cleanser and preparation method thereof comprising salicylic acid microcapsules |
| CN111150674A (en) * | 2020-03-02 | 2020-05-15 | 上海新高姿化妆品有限公司 | Acne removing composition with mild oil control function and preparation method thereof |
| CN113101375A (en) * | 2021-05-08 | 2021-07-13 | 惠州市绿亚生物材料有限公司 | Chitosan grafted salicylic acid microcapsule and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104306166B (en) | 2018-01-26 |
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