CN104306040B - Left atrial appendage plugging device - Google Patents

Left atrial appendage plugging device Download PDF

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Publication number
CN104306040B
CN104306040B CN201410528043.7A CN201410528043A CN104306040B CN 104306040 B CN104306040 B CN 104306040B CN 201410528043 A CN201410528043 A CN 201410528043A CN 104306040 B CN104306040 B CN 104306040B
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CN
China
Prior art keywords
support
left auricle
occluder
support frame
left atrial
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Application number
CN201410528043.7A
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Chinese (zh)
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CN104306040A (en
Inventor
王超
杨永森
陈娟
周而辰
罗鹏
李博
李超
蒲忠杰
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Shanghai Shape Memory Alloy Material Co Ltd
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Shanghai Shape Memory Alloy Material Co Ltd
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Priority to CN201410528043.7A priority Critical patent/CN104306040B/en
Publication of CN104306040A publication Critical patent/CN104306040A/en
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/12168Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A61B17/12122Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder within the heart
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/12168Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure
    • A61B17/12172Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure having a pre-set deployed three-dimensional shape
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/12168Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure
    • A61B17/12177Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure comprising additional materials, e.g. thrombogenic, having filaments, having fibers or being coated

Abstract

The invention provides a left atrial appendage plugging device, which comprises a netlike support frame, wherein a shape memory silk yarn is used for weaving into the netlike support frame; the support frame is of a sphere structure; the support frame is provided with a flow chocking membrane; the shape memory silk yarn forms nodes at two ends of the support frame; at least one node is provided with an attachment joint; preferably, each of the nodes is provided with an attachment joint; the maximum periphery of the support frame is provided with a plurality of thorns of which the tip ends face the attachment joint at one end of the support frame; the two attachment joints are symmetrical about the circumferential surface where the maximum periphery is positioned. The body of the left atrial appendage plugging device adopts the sphere structure, the shape formed by unfolding of the sphere can well meet the requirements of the inner shapes of different left atrial appendages, and the adaptability during plugging is greatly increased; the left atrial appendage plugging device is also provided with structures, such as the thorns and support arms, the device can be well positioned in the left atrial appendage, and the plugging effect is good. The left atrial appendage plugging device disclosed by the invention has the advantages of being simple in whole structure and low in cost.

Description

Occluder for left auricle
Technical field
The present invention relates to a kind of medical apparatus and instruments, more particularly to a kind of occluder for left auricle for left atrial appendage occlusion art.
Background technology
At present, just there is 1 people to suffer from apoplexy during the whole world is per 6 people, just had a people to die from apoplexy per 6 seconds;Ministry of Public Health is also Disclose Chinese dead because of apoplexy every year and account for the 22.45% of all death tolls.The apoplexy of 15%-20% is drawn by atrial fibrillation Rise, and have more than 90% thrombosis to be formed in left auricle in patients with atrial fibrillation, Left atrial appendage is formed increases by 3 times of apoplexy danger Danger.In cardiac dysrhythmia, thrombosiss are 10%- in the case of left auricle (Left Atrial Appendage) 20%.Oral anticoagulation thing can reduce atrial fibrillation or the probability of apoplexy occurs, but because anticoagulant can greatly increase intracranial The probability of bleeding so that having the patient of contraindication to anticoagulant cannot adopt in this way.
With the development of Interventional cardiology, there is the patients with atrial fibrillation of contraindication to anticoagulant therapy, interventional method can be closed Left auricle and then prevention embolic complication and apoplexy, interventional method utilizes special medical apparatus --- occluder for left auricle, Left auricle is blocked by occluder for left auricle can be prevented atrial fibrillation and then reduce the risk of apoplexy, and its action principle is:Zuo Xin Polymeric film in ear stopper can close the left atrium entrance of left auricle, isolation left auricle and left atrium, prevent blood flow phase It is logical;Occluder for left auricle is inserted after left auricle, and left atrium endotheliocyte can be climbed in polymer film surface and covered, new after a period of time Endothelial tissue cover, left atrium is closed after endothelialization, and then prevents thrombosiss.The implantation of occluder for left auricle is general There are two methods:The first is by the atrial septal puncture sheath of intervention particular design and then by conduit implantation release left atrial appendage occlusion Device, this method is referred to as atrial septal puncture implantation or the implantation of abbreviation left atrium;Its two by surgery directly from left auricle external puncture Implantation occluder for left auricle, this method is commonly referred to as the implantation of left auricle outside.Actual feelings of the above two method according to patient The experience of condition and doctor is selected.Because two methods belong to different technological means, its use device and left auricle Stopper there is also certain difference, and existing occluder for left auricle is not very perfect yet, still exist it is easy to fall off and because Cause to stop the situation of blood effect on driving birds is not good to position unstable, so how to solve above-mentioned deficiency is those skilled in the art Technical problem urgently to be resolved hurrily.
The content of the invention
The technical problem to be solved in the present invention is to provide a kind of simple structure, effectively can fit with left auricle inwall and play The occluder for left auricle of plugging action, to overcome the drawbacks described above of prior art.
In order to solve above-mentioned technical problem, the present invention is adopted the following technical scheme that:A kind of occluder for left auricle, including shape The network of memory silk thread braiding, the support is a sphere structure, and the support is provided with choked flow film, the shape memory Silk thread collects to form node at the two ends of support, and at least one node is provided with jointing.
Preferably, jointing is respectively equipped with described two nodes, the largest circumference of the support is provided with multiple points The anchor towards support one end jointing is held to pierce, the periphery that described two jointing relative maximum circumference are located is symmetrical.
Further, the material of the anchor thorn and shape memory silk thread is nitinol alloy wire.
Preferably, wherein a node side forms a tapered protrusion to the support, and the jointing is in cone In the raised cone of shape.
Further, the tapered protrusion is provided with multiple support arms that can be bent, and one end of the support arm is fixed In tapered protrusion, the other end is supported on left auricle inwall.
Preferably, the internal stent, is provided between the two nodes the elastic component for providing pulling force.
Further, the elastic component is extension spring.
Preferably, the two ends of the support are planar end surface, and the jointing is in the centre position of planar end surface.
As described above, occluder for left auricle of the present invention, has the advantages that:
Occluder for left auricle of the present invention utilizes nitinol alloy wire braided design, after main body adopts sphere structure, spheroid to strut Shape can be good at meeting the needs of different left atrial appendage forms, considerably increase adaptability of closure when using, and And because this device while designing using sphere structure, is additionally provided with the structures such as anchor thorn, support arm, so its with left auricle in The fitting area of wall is bigger, laminating stability is more preferable, and plugging effect is also just more preferably.
Overall structure of the present invention is simple, and cost is relatively low, and this device is provided with two jointings, it is possible to while full Sufficient left atrium implantation and left auricle outside are implanted into the needs of both operation methods, substantially increase motility during operation, cure Life can adopt different operation methods according to the practical situation of patient, therefore this device possesses very big use value and development Prospect.
Description of the drawings
Fig. 1 is the first structure chart of the present invention.
Fig. 2 is the schematic perspective view of Fig. 1.
Fig. 3 is a kind of set-up mode schematic diagram of choked flow film in the present invention.
Fig. 4 is second structure chart of the present invention.
Fig. 5 is the third structure chart of the present invention.
Fig. 6 is the preferred implementation of Fig. 5.
Fig. 7 is the 4th kind of structure chart of the present invention.
In figure:The tapered protrusion of 1 support 11
The jointing of 2 choked flow film 3
4 anchors pierce 6 support arms
5 elastic components
Specific embodiment
Structure, ratio, size depicted in Figure of description etc., only to coordinate the content disclosed in description, with Understand and read for those skilled in the art, be not limited to enforceable qualificationss of the invention, therefore do not have technically Essential meaning, the modification of any structure, the change of proportionate relationship or the adjustment of size can be generated the present invention is not being affected Under effect and the purpose to be reached, all should still fall in the range of disclosed technology contents to be covered.Meanwhile, In this specification it is cited such as " on ", D score, "front", "rear", " centre " term, be merely convenient to describe understands, and It is not used to limit enforceable scope of the invention, its relativeness is altered or modified, under without essence change technology contents, when Also it is considered as enforceable category of the invention.
It is as Figure 1-Figure 2 a kind of occluder for left auricle of invention, including the network 1 of shape memory silk thread braiding, The support 1 is a sphere structure, and the support 1 is provided with choked flow film 2, and the shape memory silk thread is on the two ends of support 1 Collect to form node, at least one node is provided with jointing 3, the jointing 3 is used for and the instrument for conveying this device It is engaged.Because this device is sphere structure, by jointing 3, this device can be using left atrium implantation and the left heart Any one mode in the implantation of ear outside is performed the operation.Choked flow film 2 described in this device is sewn on support 1 by suture, choked flow Film 2 is the materials such as politef or polyethylene terephthalate, and the set-up mode of the choked flow film 2 has various, for example As shown in figure 1, one layer of choked flow film 2 is sewn on the section of support 1, the relatively described section of two nodes is symmetrical, the choked flow film 2 According to needing to be also provided with multilamellar;As shown in figure 3, choked flow film 2 can also be the form being coated on the outer surface of support 1, it can To coat completely, it is also possible to which part coats, and through verification experimental verification, the hemisphere of the covered stent 1 of choked flow film 2 just can be reached well Plugging effect, and do not affect overall performance;In addition, choked flow film 2 can also be sewn on the inner surface of support 1. In the present embodiment, inside the support 1, the elastic component 5 of pulling force is provided between the two nodes, the elastic component 5 is played and furthered The effect at this device two ends, makes the centre position of this device because pressure at two ends is subject to and forms outside tension force, and then more Left auricle inwall is firmly abutted in, further, the elastic component 5 in the present embodiment is extension spring.
In the present embodiment, jointing 3 is respectively equipped with described two nodes, is set in the largest circumference of the support 1 There are multiple tips to pierce 4 towards the anchor of one end jointing 3 of support 1, the circle that the relative maximum circumference of described two jointings 3 is located Side face is symmetrical.Further, the anchor thorn 4 was uniformly arranged on the maximum week of support 1, it is ensured that support locating effect.Pass through The effect of anchor thorn 4 can allow positioning of this device in left auricle more firm.After in this device implantation left auricle, anchor thorn 4 Tip towards left atrium side, and then prevent this device from shedding in left atrium;In order to ensure left atrium implantation and the left heart The implantation of ear outside can be carried out, and on two nodes jointing 3 is respectively provided with.Heretofore described anchor pierces 4 and shape Memory silk thread is nitinol alloy wire.In addition, in order to allow anchor thorn 4 to have bigger deformation quantity, can have more in release Big adaptability, the anchor thorn 4 is U-shaped, i.e., in bending, and then reserved bigger deformation surplus.
As shown in figure 4, the support 1 wherein node side forms a tapered protrusion 11, it is described to connect 3 in the cone of tapered protrusion 11.In the present embodiment preferably, the jointing 3 is provided with two, and one of them is in cone In the cone of shape projection 11, another causes the present invention to plant from left auricle outside on the node of the other end of support 1 Enter left auricle, can be implanted in left auricle from left atrium again.Because left auricle inner chamber is irregular, inner chamber and left atrium communicate one Side is larger, and opposite side is less, and the part of tapered protrusion 11 can preferably adapt to the less side of left auricle, is easy to this device with a left side Auricle inwall support sticker is leaned on.
As shown in figure 5, the tapered protrusion 11 is provided with multiple support arms 6 that can be bent, one end of the support arm 6 It is fixed in tapered protrusion 11, the other end is supported on left auricle inwall, further, the support arm 6 is evenly distributed in On one circumference, so as to playing positioning and the heart being acted on.So-called is exactly to prevent support 1 from offseting, reversing to the heart, it is to avoid because skew Or reverse and can not play a part of to stop blood, because support arm 6 is evenly distributed on a circumference, it is possible to adjust The pressure that inwall is produced to it in left auricle, the pressure for allowing each support arm 6 to be subject to is as far as possible equal, further ensures that this device Supporting & stablizing in left auricle.
As shown in fig. 6, for the preferred implementation of Fig. 5, U-shaped structures of the anchor thorn 4 to put upside down therein, because anchor thorn 4 is Nickel-titanium alloy material, so there is good bending property, and U-shaped structure is even more and makes its elastic performance be further enhanced, Therefore, anchor thorn 4 being designed to into U-shaped structure can not only reach the effect that is supported on left auricle inwall, while anchor thorn 4 can be avoided Tip directly withstands on left auricle inwall.The tip of anchor thorn 4 does not directly withstand on left auricle inwall can just reduce endothelialization speed, have Operation when taking out stopper is needed beneficial to the later stage.The anchor thorn 4 of U-shaped structure is improved because of elastic performance, it is possible to having Overall stress of the effect control present invention in left auricle, prevents unbalance stress from causing skew, affects plugging effect.
Another embodiment of the invention is illustrated in figure 7, the two ends of shown support 1 are planar end surface, and the connection connects 3 in the centre position of planar end surface, can so reduce this device and the volume in left atrium and left auricle be taken and is affected.
The present invention is identical with the occluder for left auricle of routine in the using method of operation, is all to be implanted into the left heart by sheath Ear, is then pushed out discharging, being supported on the inwall of left auricle by means of delivery.
In sum, occluder for left auricle of the present invention, can solve the problem that occluder for left auricle of the prior art positioning it is unstable, Stop the problem of blood effect on driving birds is not good.So, the present invention effectively overcomes some practical problems of the prior art so as to have very High value and use meaning.
The principle and its effect of the above-mentioned embodiment only illustrative present invention, it is of the invention not for limiting.This It is bright to also have many aspects to be improved on the premise of without prejudice to overall thought, for those skilled in the art all can be Without prejudice under the spirit and the scope of the present invention, modifications and changes can be carried out to above-described embodiment.Therefore, art such as All equivalent modifications that middle tool usually intellectual is completed under without departing from disclosed spirit and technological thought or Change, should be covered by the claim of the present invention.

Claims (5)

1. a kind of occluder for left auricle, it is characterised in that:Including the network (1) of shape memory silk thread braiding, the support (1) it is a sphere structure, the support (1) is provided with choked flow film (2), the shape memory silk thread converges at the two ends of support (1) Collection forms node, and jointing (3) is respectively equipped with described two nodes, and the largest circumference of the support (1) is provided with multiple (4) are pierced in tip towards the anchor of support (1) one end jointing (3), and anchor thorn (4) is U-shaped, described two jointings (3) The periphery that relative maximum circumference is located is symmetrical, and wherein a node side forms a tapered protrusion to the support (1) (11), the jointing (3) is in the cone of tapered protrusion (11), and the tapered protrusion (11) is provided with and multiple can bend Support arm (6), support arm (6) to tapered protrusion (11) curving, one end of the support arm (6) are fixed on tapered protrusion (11) on, the other end is supported on left auricle inwall.
2. occluder for left auricle according to claim 1, it is characterised in that:Anchor thorn (4) and shape memory silk thread Material is nitinol alloy wire.
3. occluder for left auricle according to claim 1, it is characterised in that:The support (1) is internal, two nodes it Between be provided with provide pulling force elastic component (5).
4. occluder for left auricle according to claim 3, it is characterised in that:The elastic component (5) is extension spring.
5. occluder for left auricle according to claim 1, it is characterised in that:The two ends of the support (1) be planar end surface, institute Jointing (3) is stated in the centre position of planar end surface.
CN201410528043.7A 2014-10-09 2014-10-09 Left atrial appendage plugging device Active CN104306040B (en)

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CN104306040B true CN104306040B (en) 2017-04-26

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CN104905840B (en) * 2015-06-12 2018-03-30 上海申淇医疗科技有限公司 A kind of occluder for left auricle skeleton
CN106344082B (en) * 2016-09-28 2019-01-25 宁波迪创医疗科技有限公司 A kind of left ventricle capacity-reduction device
CN107595347B (en) 2017-09-25 2019-11-26 潘湘斌 A kind of the left atrial appendage occlusion device assembly and its interventional method of repeatable folding and unfolding
DE102019100530B4 (en) * 2019-01-10 2021-05-06 Qatna Medical GmbH Occluder and system for introducing an occluder
CN214387792U (en) * 2019-09-20 2021-10-15 杭州启明医疗器械股份有限公司 Closure film article for interventional devices
CN110720961B (en) * 2019-10-28 2021-01-22 西安交通大学医学院第一附属医院 Left auricle plugging device

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