CN104288459A - Medicine for treating erectile dysfunction and preparation method thereof - Google Patents

Medicine for treating erectile dysfunction and preparation method thereof Download PDF

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Publication number
CN104288459A
CN104288459A CN201410523703.2A CN201410523703A CN104288459A CN 104288459 A CN104288459 A CN 104288459A CN 201410523703 A CN201410523703 A CN 201410523703A CN 104288459 A CN104288459 A CN 104288459A
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CN
China
Prior art keywords
medicine
radix
herba epimedii
cortex moutan
achyranthis bidentatae
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Pending
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CN201410523703.2A
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Chinese (zh)
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张旭
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Individual
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Individual
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Priority to CN201410523703.2A priority Critical patent/CN104288459A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296Epimedium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/344Codonopsis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8962Allium, e.g. garden onion, leek, garlic or chives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2068Compounds of unknown constitution, e.g. material from plants or animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Botany (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a medicine for treating erectile dysfunction. The preparation method mainly comprises the following steps: by taking herba epimedii, prepared rehmannia root, semen allii tuberose, codonopsis pilosula, Lycium barbarum, radix achyranthis bidentatae, cortex moutan and liquorice as raw materials, repeatedly decocting by using slow fire, and concentrating the liquid medicine into thick paste; adding the obtained thick paste into the conventional auxiliary materials, drying, grinding and preparing powder; and packaging, thereby obtaining a finished product. The medicine disclosed by the invention has the effects of invigorating the kidney and strengthening Yang and reinforcing the kidney and controlling noctural emission and can be used for treating various types of erectile dysfunction.

Description

A kind of medicine for the treatment of sexual impotence and preparation method thereof
Technical field
The present invention relates to a kind of medicine for the treatment of sexual impotence, being related specifically to a kind of take Chinese herbal medicine as the medicine for the treatment of sexual impotence prepared by raw material, the invention still further relates to the preparation method of this medicine.
Background technology
Along with continuing to increase of man's life stress, increasing man has suffered from the disease of sexual impotence, sexual impotence mainly refers to when there being libido to require, penis anorthosis or erect not hard, although or have erection and have hardness to a certain degree, the enough time of sexual intercourse can not be kept, thus hinder sexual intercourse maybe can not complete sexual intercourse, have a strong impact on goodwill as between spouses, even threaten the stable of marriage.At present, the Western medicine for the treatment of sexual impotence is a lot, and such as viagra etc., cardinal principle is blood vessel dilating, makes penis normal erection, but this type of medicine has the shortcomings such as treatment cost is high, side effect is large.In addition, also have the Chinese medicine of a lot for the treatment of sexual impotence, but great majority have the shortcomings such as the low and treatment cycle of therapeutic effect difference, cure rate is long.
Summary of the invention
The present invention aims to provide the medicine of the treatment sexual impotence that a kind of cure rate is high, cost is low, have no side effect.
The preparation method of this medicine is provided to be another goal of the invention of the present invention.
Medicine of the present invention is made up of the raw material of following mass ratio:
Herba Epimedii 10-16 Radix Rehmanniae Preparata 10-20
Semen Allii Tuberosi 5-16 Radix Codonopsis 7-15
Fructus Lycii 6-18 Radix Achyranthis Bidentatae 6-15
Cortex Moutan 8-25 Radix Glycyrrhizae 6-20
Specifically be made up of the raw material of following mass ratio:
Herba Epimedii 12 Radix Rehmanniae Preparata 15
Semen Allii Tuberosi 13 Radix Codonopsis 10
Fructus Lycii 13 Radix Achyranthis Bidentatae 11
Cortex Moutan 15 Radix Glycyrrhizae 12
The preparation method of medicine of the present invention is:
Herba Epimedii, Radix Rehmanniae Preparata, Semen Allii Tuberosi, Radix Codonopsis, Fructus Lycii, Radix Achyranthis Bidentatae, Cortex Moutan and Radix Glycyrrhizae are added the clear water of 60-120 weight portions, 0.5-1.5 hours at a simmer, after repeatedly decocting 3 times, take out medicinal residues, marmite is put in 3 medicinal liquid mixing and decocts 2-4 hours, concentration of liquid medicine is become paste, then adds customary adjuvant, make the tablet of clinical acceptance, capsule, pill, granule, powder, injection or unguentum.
Have between each medicine in prescription of the present invention and be added complementary and synergism, kidney invigorating and YANG supporting, reinforcing the kindey to control nocturnal emission, effectively can treat sexual impotence.
The present invention is that inventor is through repeatedly studying, progressively improve, last successful a kind of curative effect treats the medicine of sexual impotence preferably, for showing the therapeutic effect of medicine of the present invention to sexual impotence, the present invention has carried out clinical observation to the impotence patient that 260 examples take this medicine, and selection has impotence patient 259 example of comparability as a control group.Treatment group patient takes medicine twice of the present invention every day, and sooner or later respectively once, once take 5 grams of medicines, matched group patient takes the oral drugs of conventional therapy sexual impotence.Treat after one month, therapeutic outcome is in table 1
Table 1 treatment group and treatment of control group result synopsis
? Cure Effectively Cure rate Effective percentage
Treatment group 201 examples 229 examples 77.31% 88.08%
Matched group 164 examples 177 examples 63.32% 68.34%
Treatment group is compared matched group and is had higher cure rate and effective percentage, thinks thus, and Drug therapy sexual impotence of the present invention has good effect, and through the Ureteral Calculus of month, takes medicine of the present invention and do not occur any toxic and side effects.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail, but does not form any limitation of the invention.
Embodiment 1
Raw material (kg) is prepared according to following weight:
Herba Epimedii 1.5, Radix Rehmanniae Preparata 1.7, Semen Allii Tuberosi 1.1, Radix Codonopsis 1.1, Fructus Lycii 1.3, Radix Achyranthis Bidentatae 0.8, Cortex Moutan 1.2 and Radix Glycyrrhizae 0.8.
Above-mentioned 9.5kg Chinese herbal medicine is put into marmite, adds the clear water of 10.0kg, 1.5 hours at a simmer, after repeatedly decocting 3 times, take out medicinal residues, marmite is put in 3 medicinal liquid mixing again and decocts 3.5 hours, concentration of liquid medicine is become paste, then adds refined honey, mix homogeneously, makes big honeyed pills, obtains finished product after packaging.
Embodiment 2
Raw material (kg) is prepared according to following weight:
Herba Epimedii 1.2, Radix Rehmanniae Preparata 1.5, Semen Allii Tuberosi 1.3, Radix Codonopsis 1.0, Fructus Lycii 1.3, Radix Achyranthis Bidentatae 1.1, Cortex Moutan 1.5 and Radix Glycyrrhizae 1.2.
Above-mentioned 10.1kg Chinese herbal medicine is put into marmite, add the clear water of 11kg, 1.5 hours at a simmer, after repeatedly decocting 3 times, take out medicinal residues, marmite is put in 3 medicinal liquid mixing again and decocts 3.5 hours, concentration of liquid medicine is become paste, then the paste medicine of gained dried, grind, encapsulated, after packaging finished product.

Claims (3)

1. treat a medicine for sexual impotence, it is characterized in that described medicine is made up of the raw material of following mass ratio:
Herba Epimedii 10-16 Radix Rehmanniae Preparata 10-20
Semen Allii Tuberosi 5-16 Radix Codonopsis 7-15
Fructus Lycii 6-18 Radix Achyranthis Bidentatae 6-15
Cortex Moutan 8-25 Radix Glycyrrhizae 6-20.
2. the medicine for the treatment of sexual impotence according to claim 1, is characterized in that described medicine is made up of the raw material of following mass ratio:
Herba Epimedii 12 Radix Rehmanniae Preparata 15
Semen Allii Tuberosi 13 Radix Codonopsis 10
Fructus Lycii 13 Radix Achyranthis Bidentatae 11
Cortex Moutan 15 Radix Glycyrrhizae 12.
3. the preparation method of the medicine for the treatment of sexual impotence according to claim 1, it is characterized in that Herba Epimedii, Radix Rehmanniae Preparata, Semen Allii Tuberosi, Radix Codonopsis, Fructus Lycii, Radix Achyranthis Bidentatae, Cortex Moutan and Radix Glycyrrhizae are added the clear water of 70-130 weight portions by the method, 0.5-1.5 hours at a simmer, after repeatedly decocting 3 times, take out medicinal residues, marmite is put in 3 medicinal liquid mixing and decocts 2-4 hours, concentration of liquid medicine is become paste, then add customary adjuvant, make the tablet of clinical acceptance, capsule, pill, granule, powder, injection or unguentum.
CN201410523703.2A 2014-10-08 2014-10-08 Medicine for treating erectile dysfunction and preparation method thereof Pending CN104288459A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201410523703.2A CN104288459A (en) 2014-10-08 2014-10-08 Medicine for treating erectile dysfunction and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201410523703.2A CN104288459A (en) 2014-10-08 2014-10-08 Medicine for treating erectile dysfunction and preparation method thereof

Publications (1)

Publication Number Publication Date
CN104288459A true CN104288459A (en) 2015-01-21

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CN201410523703.2A Pending CN104288459A (en) 2014-10-08 2014-10-08 Medicine for treating erectile dysfunction and preparation method thereof

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100686951B1 (en) * 2006-05-26 2007-03-02 주식회사 케이엠에스아이 A composition having antioxidation effect for preventing or treating impotence
CN101045125A (en) * 2007-04-16 2007-10-03 张晓辉 Traditional Chinese medicine for treating sexual disorders and its preparing method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100686951B1 (en) * 2006-05-26 2007-03-02 주식회사 케이엠에스아이 A composition having antioxidation effect for preventing or treating impotence
CN101045125A (en) * 2007-04-16 2007-10-03 张晓辉 Traditional Chinese medicine for treating sexual disorders and its preparing method

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
姜玉石: "《***与健康》", 31 December 2006, 黑龙江人民出版社 *
江西药科学校革命委员会: "《草药手册》", 31 January 1970, 江西新华印刷厂 *

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Application publication date: 20150121