CN104280704B - Gradient pulse wave design method and device are detected in movement for magnetic resonance - Google Patents
Gradient pulse wave design method and device are detected in movement for magnetic resonance Download PDFInfo
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Abstract
The invention discloses the movements for magnetic resonance to detect gradient pulse wave design method and device.The method comprising the steps of: b value and the duration of gradient pulse are detected in setting movement；And determine that the waveform of gradient pulse is detected in movement according to the b value of setting and duration, so that the corresponding movement gradient probe pulse of the waveform is less than in the average amplitude within the corresponding half duration for returning poly- pulse far from the average amplitude in corresponding the other half duration for returning poly- pulse.The b value of the MPG pulse of technical solution of the present invention design and MPG pulsion phase in the prior art are same, current strength needed for required current strength is less than generation MPG pulse in the prior art.
Description
Technical field
The present invention relates to technical field of medical equipment, in particular to the gradient pulse technical field of magnetic resonance.
Background technique
In the various imaging techniques of magnetic resonance, Diffusion-Weighted MR Imaging (Diffusion Weighted Imaging, DWI)
It is one kind of new development, is imaged using the tissue contrast that diffusion coefficient difference between tissue generates, is a kind of be different from often
The method for advising magnetic resonance imaging can carry out non-invasive inspection in institutional framework and functional status of the molecular level to organism
It looks into.
When being diffused weighted imaging, need to select in gradient, phase encoding gradient and readout gradient in lamella
On at least one, apply diffusion gradient (diffusion gradient) pulse train, gradient (Motion is detected in also referred to as movement
Probing Gradient, MPG) pulse train.
Generally reflect the influence size of MPG pulse with b value (b-factor) in the prior art, γ is constant, and TE is back
Wave time, G (t) are the function for indicating the waveform of the MPG pulse.
B value is higher, and the picture quality of obtained Diffusion-Weighted MR Imaging is better.But to generate the MPG arteries and veins of high b value
Punching, needs very big output power.And the output power that existing power amplifier can generate has a upper limit, it may be assumed that
Output power cannot be improved ad infinitum.
The method of existing design MPG impulse waveform is all to try to so that the waveform of the MPG pulse designed is close to rectangle,
And meet some other requirement, and such as: the time interval etc. between b value, pulse duration, MPG pulse and time poly- pulse.
Fig. 1 schematically shows a kind of MPG impulse wave figure of existing method design.Horizontal axis in Fig. 1 indicates the time, indulges
The amplitude of axis expression pulse.Apply the time of MPG pulse train after excitation pulse 101.MPG pulse train is only applied
On phase encoding gradient GP.It returns poly- pulse 103 and only has one.If for the time sequencing for applying these MPG pulses,
First MPG pulse 102 and second MPG pulse 104 in MPG pulse train can be applied to back in couples poly- pulse 103
Two sides, it may be assumed that the application time of first MPG pulse 102 return poly- pulse 103 application time before, second MPG pulse
Application time return poly- pulse 103 application time after.The waveform of MPG pulse 102 and 104 can be about time poly- pulse
103 is symmetrical.
Fig. 2 schematically shows another MPG impulse wave figures of existing method design.Horizontal axis in Fig. 2 indicates the time,
The amplitude of longitudinal axis expression pulse.Apply the time of MPG pulse train after excitation pulse 201.MPG pulse train is applied in
Lamella selects on gradient G S, phase encoding gradient GP and readout gradient GR.It returns there are two poly- pulses 203 and 206 altogether.To apply
For the MPG pulse train on lamella selection gradient G S, first MPG pulse 202 in MPG pulse train and second
MPG pulse 204 can be applied to first two sides for returning poly- pulse 203 in couples, it may be assumed that when the application of first MPG pulse 202
Between before first is returned the application time of poly- pulse 203, the application time of second MPG pulse 204 returns poly- arteries and veins at first
After the application time of punching 203.Equally, the third MPG pulse 205 in MPG pulse train and the 4th 207 meeting of MPG pulse
It is applied to second two sides for returning poly- pulse 206 in couples, it may be assumed that the application time of third MPG pulse 205 is returned at second
Before the application time of poly- pulse 206, the application time of the 4th MPG pulse 207 is in second application for returning poly- pulse 206
Between after.The waveform of MPG pulse 202 and 207 can be symmetrical about its center time point, and the waveform of MPG pulse 204 and 205
It can be symmetrical about its center time point.The position of the MPG pulse train applied in other two gradients and lamella select gradient G S
On MPG pulse train position it is identical.
The method of existing design MPG impulse wave is when designing the waveform of MPG pulse it can be seen from Fig. 1 and Fig. 2, all
It is the pulse for selecting very close rectangle, waveform symmetry, it may be assumed that for each MPG pulse, all have one and be parallel to the longitudinal axis
Symmetry axis so that the MPG pulse is about the axis from symmetrical.The slope value of the rising edge of such pulse and failing edge it is very big and
It is equal, flat-top area also only one.Also, how the introduction about MPG Pulse Design in the prior art is all concerned only with by MPG
The Waveform Design of pulse is at as far as possible close to rectangle.
Such MPG pulse, although very big b value can be generated, its required power is very big.Therefore, how
While generating high b value, the power of needs can reduce, in other words, generate higher b value with identical power, be this
The field technical issues that need to address.
Summary of the invention
The main purpose of the present invention is to provide the movements for magnetic resonance to detect gradient pulse wave design method and device,
To solve the above problem of the existing technology, in which:
According to the first aspect of the invention, it provides and detects gradient pulse wave design method for the movement of magnetic resonance, wrap
Include step: setting is described to move b value and the duration for detecting gradient pulse；And it is true according to the b value of setting and duration
The waveform of gradient pulse is detected in movement calmly, is gathered so that gradient pulse is detected in the corresponding movement of the waveform close to corresponding returning
Average amplitude in the half duration of pulse is less than to return in the other half duration of poly- pulse far from corresponding
Average amplitude.
According to the second aspect of the invention, it provides and detects gradient pulse wave design device, packet for the movement of magnetic resonance
Include: parameter setting module detects b value and the duration of gradient pulse for setting the movement；Waveform determining module, is used for
Determine that the waveform of gradient pulse is detected in movement according to the b value of setting and duration, so that ladder is detected in the corresponding movement of the waveform
Pulse is spent to be less than in the average amplitude within the corresponding half duration for returning poly- pulse far from corresponding
Return the average amplitude in the other half duration of poly- pulse.
Compared with prior art, the b value of the MPG pulse of technical solution of the present invention design and MPG arteries and veins in the prior art
Rush identical, current strength needed for required current strength (that is: power) is less than generation MPG pulse in the prior art.
Detailed description of the invention
The drawings described herein are used to provide a further understanding of the present invention, constitutes a part of the invention, this hair
Bright illustrative embodiments and their description are used to explain the present invention, and are not constituted improper limitations of the present invention.In the accompanying drawings:
Fig. 1 schematically shows a kind of MPG impulse wave figure of existing method design；
Fig. 2 schematically shows another MPG impulse wave figures of existing method design；
Fig. 3 schematically shows the movement proposed by the present invention for magnetic resonance and detects gradient pulse wave design method
Flow chart；
Fig. 4 schematically shows the waveform diagrams of the MPG pulse designed according to the proposed method；
Fig. 5 schematically shows the waveform diagram of the MPG pulse designed according to the proposed method；
Fig. 6 schematically shows the waveform diagram of the MPG pulse designed according to the proposed method；
Fig. 7 schematically shows the waveform diagram of the MPG pulse designed according to the proposed method；
Fig. 8 schematically shows the waveform diagram of the MPG pulse designed according to the proposed method；
Fig. 9 schematically shows the movement proposed by the present invention for magnetic resonance and detects gradient pulse wave design device
Block diagram.
In the drawings, the same or similar part is indicated using identical reference label.
Specific embodiment
To make the object, technical solutions and advantages of the present invention clearer, below in conjunction with drawings and the specific embodiments, to this
Invention is described in further detail.
For the sake of simplicity, some technical features known to those skilled in the art are omitted in being described below.
The invention proposes a kind of movements for magnetic resonance to detect gradient pulse wave design method.Fig. 3 schematically shows
The flow chart that gradient pulse wave design method 300 is detected in the movement proposed by the present invention for magnetic resonance is gone out.Method 300 includes
Following steps 301 to 302.
In step 301, b value and the duration of gradient pulse are detected in setting movement.An implementation according to the present invention
Example, can set b value and duration to the general requirement of technical indicator according to magnetic resonance machine.
In step 302, determine that the waveform of gradient pulse is detected in movement according to the b value of setting and duration, so that should
The corresponding movement of waveform detects gradient pulse in the average amplitude within the corresponding half duration for returning poly- pulse
Less than far from the average amplitude in corresponding the other half duration for returning poly- pulse.
According to one embodiment of present invention, the MPG impulse waveform that can be met the requirements in all b values and duration
In, it finds out any one and is less than in the close average amplitude in the half duration of corresponding time poly- pulse of the MPG pulse
Separate with a MPG pulse of the average amplitude in the other half duration of corresponding time poly- pulse of the MPG pulse, by it
Waveform is determined as the waveform of MPG pulse.
It according to one embodiment of present invention, can also be by b value, the restrictive condition of duration and some other pair of pulse
(such as: the rising edge of pulse, the slope of failing edge, the number in flat-top area, number of subpulse etc.) combine, meeting this
In the waveform for the MPG pulse that a little conditions require, a MPG impulse waveform is selected, so that the MPG pulse is close to corresponding
The average amplitude returned in the half duration of poly- pulse be less than far from it is corresponding return poly- pulse it is another semi-continuous when
Interior average amplitude.It according to one embodiment of present invention, can applying MPG pulse after the waveform for determining MPG pulse
It is determined after the application time of excitation pulse between added-time.According to one embodiment of present invention, excitation pulse can be non-empty
Between spectral selectivity pulse.According to another embodiment of the invention, returning poly- pulse can be spatial spectrum selective pulse
(Spatial Spectral Selective Pulse)。
Fig. 4 schematically shows the waveform diagrams of the MPG pulse designed according to the proposed method.As shown in figure 4,
Horizontal axis indicates the time, and the longitudinal axis indicates the amplitude in arteries and veins.The duration of MPG pulse 400 be t2-t1, return poly- pulse 401 be with
400 corresponding times poly- pulses of MPG pulse.The axis 402 for being parallel to the longitudinal axis being represented by dashed line is located at time point (t2-t1)/2
Place, it may be assumed that the midpoint of the duration of MPG pulse 400.The b value of rectangular pulse 403 in Fig. 4 and the b value phase of MPG pulse 400
Deng, the duration of rectangular pulse 403 and the duration of MPG pulse 400 are equal, rectangular pulse 403 with return poly- pulse 401
Interval time and MPG pulse 400 are equal with the interval time of poly- pulse 401 is returned.
As seen from Figure 4, MPG pulse 400 is small in the average amplitude within the half duration for returning poly- pulse 401
In far from the average amplitude in the other half duration for returning poly- pulse 401.That is, MPG pulse 400 from t1 to
(t2-t1)/2 the average amplitude in the period is less than from (t2-t1)/2 to the average amplitude in the t2 period.
Using the MPG pulse 400 of waveform shown in Fig. 4, can produce out with existing rectangle or close to the MPG pulse of rectangle
400 identical b values, at the same can reduce generate MPG pulse needed for average current intensity, also just reduce need to consume it is flat
Equal power.
Fig. 5 schematically shows the waveform diagram of the MPG pulse designed according to the proposed method.As shown in figure 5,
Horizontal axis indicates the time, and the longitudinal axis indicates the amplitude of pulse.The duration of MPG pulse 500 be t2-t1, return poly- pulse 501 be with
500 corresponding times poly- pulses of MPG pulse.The axis 502 for being parallel to the longitudinal axis being represented by dashed line is located at time point (t2-t1)/2
Place, it may be assumed that the midpoint of the duration of MPG pulse 400.The b value of rectangular pulse 503 in Fig. 5 and the b value phase of MPG pulse 500
Deng, the duration of rectangular pulse 503 and the duration of MPG pulse 500 are equal, rectangular pulse 503 with return poly- pulse 501
Interval time and MPG pulse 500 are equal with the interval time of poly- pulse 501 is returned.
As seen from Figure 5, MPG pulse 500 is small in the average amplitude within the half duration for returning poly- pulse 501
In far from the average amplitude in the other half duration for returning poly- pulse 501.That is, MPG pulse 500 from t1 to
(t2-t1)/2 the average amplitude in the period is less than from (t2-t1)/2 to the average amplitude in the t2 period.
MPG pulse 500 shown in fig. 5 contains two subpulses 504 and 505.Time of the two subpulses in application
On can adjoin each other together, it may be assumed that between two subpulses can not have time interval, can also be with having time interval.Fig. 5 shows
Out be the case where subpulse 504 and 505 adjoins each other.The duration of two subpulses can be equal, can not also wait.
It should be noted that Fig. 5 merely illustrates the case where MPG pulse 500 contains two subpulses 504 and 505, it is practical
On, MPG pulse of the invention may include more subpulses.
Using the MPG pulse 500 of waveform shown in Fig. 5, can produce out with existing rectangle or close to the MPG pulse of rectangle
500 identical b values, at the same also can reduce generate MPG pulse needed for average current intensity, also just reduce and need to consume
Mean power.
Fig. 6 schematically shows the waveform diagram of the MPG pulse designed according to the proposed method.It is shown in fig. 6
The rising edge and failing edge of MPG pulse 600 have different slopes.
As shown in fig. 6, horizontal axis indicates the time, the longitudinal axis indicates the amplitude of pulse.The duration of MPG pulse 600 is t2-
T1, returning poly- pulse 601 is corresponding with MPG pulse 600 time poly- pulse.602, the axis for being parallel to the longitudinal axis be represented by dashed line
At time point (t2-t1)/2, it may be assumed that the midpoint of the duration of MPG pulse 600.The b value of rectangular pulse 603 in Fig. 6 and
The b value of MPG pulse 600 is equal, and the duration of rectangular pulse 603 and the duration of MPG pulse 600 are equal, rectangular pulse
603 is equal with the interval time of poly- pulse 601 is returned with the interval time and MPG pulse 600 for returning poly- pulse 601.
As seen from Figure 6, MPG pulse 600 is small in the average amplitude within the half duration for returning poly- pulse 601
In far from the average amplitude in the other half duration for returning poly- pulse 601.That is, MPG pulse 600 from t1 to
(t2-t1)/2 the average amplitude in the period is less than from (t2-t1)/2 to the average amplitude in the t2 period.
Using the MPG pulse 600 of waveform shown in Fig. 6, also can produce out with existing rectangle or close to the MPG arteries and veins of rectangle
Rush 600 identical b values, at the same can reduce generate MPG pulse needed for average current intensity, also just reduce and need to consume
Mean power.
Fig. 7 schematically shows the waveform diagram of the MPG pulse designed according to the proposed method.It is shown in Fig. 7
There are two flat-top areas 704 and 705 for MPG pulse 700.So-called flat-top area refers to that the range value of pulse stablizes constant region.
As shown in fig. 7, horizontal axis indicates the time, the longitudinal axis indicates the amplitude of pulse.The duration of MPG pulse 700 is t2-
T1, returning poly- pulse 701 is corresponding with MPG pulse 700 time poly- pulse.702, the axis for being parallel to the longitudinal axis be represented by dashed line
At time point (t2-t1)/2, it may be assumed that the midpoint of the duration of MPG pulse 700.The b value of rectangular pulse 703 in Fig. 7 and
The b value of MPG pulse 700 is equal, and the duration of rectangular pulse 703 and the duration of MPG pulse 700 are equal, rectangular pulse
703 is equal with the interval time of poly- pulse 701 is returned with the interval time and MPG pulse 700 for returning poly- pulse 701.
As seen from Figure 7, MPG pulse 700 is small in the average amplitude within the half duration for returning poly- pulse 701
In far from the average amplitude in the other half duration for returning poly- pulse 701.That is, MPG pulse 700 is from (t2-
T1)/2 it is less than to the average amplitude in the t2 period from t1 to the average amplitude in (t2-t1)/2 period.
Using the MPG pulse 700 of waveform shown in Fig. 7, also can produce out with existing rectangle or close to the MPG arteries and veins of rectangle
Rush 700 identical b values, at the same can reduce generate MPG pulse needed for equal current strength, also just reduce need to consume it is flat
Equal power.
Fig. 8 schematically shows the waveform diagram of the MPG pulse designed according to the proposed method.It is shown in Fig. 8
There are two different slope Ks 1 and K2 for the rising edge of MPG pulse 800.
As shown in figure 8, horizontal axis indicates the time, the longitudinal axis indicates the amplitude of pulse.The duration of MPG pulse 800 is t2-
T1, returning poly- pulse 801 is corresponding with MPG pulse 800 time poly- pulse.802, the axis for being parallel to the longitudinal axis be represented by dashed line
At time point (t2-t1)/2, it may be assumed that the midpoint of the duration of MPG pulse 800.The b value of rectangular pulse 803 in Fig. 8 and
The b value of MPG pulse 800 is equal, and the duration of rectangular pulse 803 and the duration of MPG pulse 800 are equal, rectangular pulse
803 is equal with the interval time of poly- pulse 801 is returned with the interval time and MPG pulse 800 for returning poly- pulse 801.
As seen from Figure 8, MPG pulse 800 is small in the average amplitude within the half duration for returning poly- pulse 801
In far from the average amplitude in the other half duration for returning poly- pulse 801.That is, MPG pulse 800 is from (t2-
T1)/2 it is less than to the average amplitude in the t2 period from t1 to the average amplitude in (t2-t1)/2 period.
The case where there are two different slopes it should be pointed out that Fig. 8 merely illustrates the rising edge of MPG pulse 800, it is practical
On, the rising edge of MPG pulse can be there are two above Different Slope, and equally, failing edge also can have two or two
Above different slopes.In addition, the rising edge and failing edge of MPG pulse can have simultaneously it is two or more tiltedly
Rate, can also be with only one of which along with two or more slopes.
Using the MPG pulse 800 of waveform shown in Fig. 8, also can produce out with existing rectangle or close to the MPG arteries and veins of rectangle
Rush 800 identical b values, at the same can reduce generate MPG pulse needed for average current intensity, also just reduce and need to consume
Mean power.
From the above, it can be seen that MPG impulse wave design method proposed by the present invention, in the waveform for determining pulse,
The prior art has been selected not adopt used some asymmetrical impulse waveforms in MPG pulse.These asymmetrical waveforms pair
The MPG pulse answered, the b value for enabling to it to generate remain unchanged, while reducing electric current required for generating MPG pulse, also
Reduce power consumption.
The invention also provides the movements for magnetic resonance to detect gradient pulse waveforms design device.Fig. 9 schematically shows
The block diagram that gradient pulse waveforms design device 900 is detected in the movement proposed by the present invention for magnetic resonance is gone out.Device 900 can be with
Include: parameter setting module 901, b value and the duration of gradient pulse are detected for setting movement；And waveform determining module
902, for determining that the waveform of gradient pulse is detected in movement according to the b value of setting and duration, so that movement gradient detects arteries and veins
The average amplitude being punched in the close corresponding half duration for returning poly- pulse is less than to be gathered far from corresponding returning
Average amplitude in the other half duration of pulse.
According to one embodiment of present invention, returning poly- arteries and veins can be spatial spectrum selective pulse.
The above description is only an embodiment of the present invention, is not intended to restrict the invention, for those skilled in the art
For member, the invention may be variously modified and varied.All within the spirits and principles of the present invention, it is made it is any modification,
Equivalent replacement, improvement etc., should be included within scope of the presently claimed invention.
Claims (10)
1. gradient pulse wave design method is detected in the movement for magnetic resonance, it is characterized in that: comprising steps of the setting movement is visited
Look into b value and the duration of gradient pulse；And
Determine that the waveform of gradient pulse is detected in movement according to the b value of setting and duration, so that the corresponding movement of the waveform is visited
Gradient pulse is looked into be less than in the average amplitude within the corresponding half duration for returning poly- pulse separate right with it
The average amplitude in the other half duration for returning poly- pulse answered.
2. according to the method described in claim 1, it is characterized in that: it includes at least two sub- arteries and veins that gradient pulse is detected in the movement
Punching.
3. according to the method described in claim 1, it is characterized in that: the slope for detecting the rising edge of gradient pulse that moves is under
The slope for dropping edge is different.
4. according to the method described in claim 1, it is characterized in that: the movement detects gradient pulse and has at least two flat-top areas.
5. according to the method described in claim 1, it is characterized in that: the rising edge for detecting gradient pulse or failing edge of moving has
At least two different slopes.
6. according to the method described in claim 1, it is characterized in that: comprising steps of the movement to be detected to the application of gradient pulse
Time determines after the application time of excitation pulse.
7. according to the method described in claim 6, it is characterized in that: the excitation pulse is the pulse of non-space spectral selectivity.
8. according to the method described in claim 1, it is characterized in that: described time poly- pulse is spatial spectrum selective pulse.
9. gradient pulse wave design device is detected in the movement for magnetic resonance, it is characterized in that: including:
Parameter setting module detects b value and the duration of gradient pulse for setting the movement；And
Waveform determining module, for determining that the waveform of gradient pulse is detected in movement according to the b value of setting and duration, so that should
The corresponding movement of waveform detects gradient pulse in the average amplitude within the corresponding half duration for returning poly- pulse
Less than far from the average amplitude in corresponding the other half duration for returning poly- pulse.
10. device according to claim 9, it is characterized in that: described time poly- pulse is spatial spectrum selective pulse.
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| CN1499218A (en) * | 2002-10-31 | 2004-05-26 | 西门子公司 | Method of determining ADC coefficient using steady sequency in diffusion weighted magnetic resonance imaging |
| CN1961826A (en) * | 2005-11-08 | 2007-05-16 | 西门子公司 | Method for obtaining a diffusion-weighted image |
| CN101143093A (en) * | 2006-09-11 | 2008-03-19 | 西门子（中国）有限公司 | Magnetic resonance diffusion imaging method |
| CN101711671A (en) * | 2008-09-29 | 2010-05-26 | 株式会社东芝 | Magnetic resonance diagnostic apparatus and magnetic resonance diagnostic method |
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Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4889127A (en) * | 1986-04-11 | 1989-12-26 | Hitachi, Ltd. | Nuclear magnetic resonance imaging apparatus |
| CN1499218A (en) * | 2002-10-31 | 2004-05-26 | 西门子公司 | Method of determining ADC coefficient using steady sequency in diffusion weighted magnetic resonance imaging |
| CN1961826A (en) * | 2005-11-08 | 2007-05-16 | 西门子公司 | Method for obtaining a diffusion-weighted image |
| CN101143093A (en) * | 2006-09-11 | 2008-03-19 | 西门子（中国）有限公司 | Magnetic resonance diffusion imaging method |
| CN101711671A (en) * | 2008-09-29 | 2010-05-26 | 株式会社东芝 | Magnetic resonance diagnostic apparatus and magnetic resonance diagnostic method |
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