CN104274750B - A kind of Chinese medicine composition for treating acute bronchitis, the infection of the upper respiratory tract - Google Patents
A kind of Chinese medicine composition for treating acute bronchitis, the infection of the upper respiratory tract Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/27—Asclepiadaceae (Milkweed family), e.g. hoya
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/535—Perilla (beefsteak plant)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
- A61K36/634—Forsythia
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/744—Gardenia
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8966—Fritillaria, e.g. checker lily or mission bells
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/904—Stemonaceae (Stemona family), e.g. croomia
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
Abstract
The present invention provides a kind of Chinese medicine composition for treating acute bronchitis, the infection of the upper respiratory tract, bulk drug is counted by weight and is：30 90 parts of mulberry leaf, 30 90 parts of semen armeniacae amarae, 30 90 parts of balloonflower root, 30 90 parts of fritillaria thunbergii, 30 90 parts of radix glehniae, 30 90 parts of Cynanchum glaucescens, 30 90 parts of the capsule of weeping forsythia, 30 60 parts of Oroxylum indicum, 30 60 parts of stiff silkworm, 30 90 parts of perilla seed, 30 90 parts of the root bark of white mulberry, 30 90 parts of the tuber of stemona, 30 90 parts of tussilago, 30 90 parts of cape jasmine.According to clinical verification, the Chinese medicine composition that prepared by the present invention can declare clearly scorching, moisten the lung and relieve the cough, resolving sputum and relieving asthma.For treating the cough caused by dryness evil hinders lung, heating is uncomfortable in chest, headache, thirsty, dry throat nasal cavity dryness；Acute bronchitis, the infection of the upper respiratory tract are shown in above-mentioned disease person.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for treating acute bronchitis, the infection of the upper respiratory tract.
Background technology
Acute bronchitis, the infection of the upper respiratory tract belong to traditional Chinese medicine " cough " category, traditional Chinese medical science cough be divided into exogenous cough with it is interior
Wound cough, exogenous cough the heresy of the six external factors which cause diseases or enters to defend outer functional disturbance from mouth and nose, or is received from fur.Enemy intrusion or invasion loses in lung, lung
" a surname respectful " then Lung Qi upward reversal and be to cough.
Find that Xinjiang region acute bronchitis, infection of the upper respiratory tract patient hinder lung type as more special with dryness evil by studying
Point.To find out its cause, may be relevant with the factor such as geography, weather, the diet in Xinjiang.Xinjiang is located at Asia continent center, and landforms are special
It is " three mountain Jia Liang basins " to levy, generally in arid climate area；Latitude is higher, and the long summer in winter is short, and temperature is relatively low, based on cold,
Often Siberia cold current attacks；Away from ocean, extensively, vegetation sparse belongs to typical continental climate, day and night temperature for Desert of Gobi
It is larger.A variety of causes causes acute bronchitis, to hinder lung type with dryness evil be many to the Syndrome Differentiation of Traditional Chinese Medicine of the infection of the upper respiratory tract.
The content of the invention
The invention provides a kind of Chinese medicine composition for treating acute bronchitis, the infection of the upper respiratory tract, can be very
Good treatment dryness evil hinders the cough and expectoration caused by lung.
The present invention provides a kind of Chinese medicine composition for treating acute bronchitis, the infection of the upper respiratory tract, by weight
Number counts bulk drug：Mulberry leaf 30-90 parts, semen armeniacae amarae 30-90 parts, balloonflower root 30-90 parts, fritillaria thunbergii 30-90 parts, radix glehniae 30-90
Part, Cynanchum glaucescens 30-90 parts, capsule of weeping forsythia 30-90 parts, Oroxylum indicum 30-60 parts, stiff silkworm 30-60 parts, perilla seed 30-90 parts, root bark of white mulberry 30-
90 parts, tuber of stemona 30-90 parts, tussilago 30-90 parts, cape jasmine 30-90 parts.
Preferably, meter bulk drug by weight is：Mulberry leaf 60-90 parts, semen armeniacae amarae 60-90 parts, balloonflower root 60-90 parts, Zhejiang
Fritillaria 60-90 parts, radix glehniae 60-90 parts, Cynanchum glaucescens 60-90 parts, capsule of weeping forsythia 60-90 parts, Oroxylum indicum 30-50 parts, stiff silkworm 30-50 parts,
Perilla seed 60-90 parts, root bark of white mulberry 60-90 parts, tuber of stemona 60-90 parts, tussilago 60-90 parts, cape jasmine 60-90 parts.
Further, meter bulk drug by weight is：75 parts of mulberry leaf, 75 parts of semen armeniacae amarae, 75 parts of balloonflower root, fritillaria thunbergii 75
Part, 75 parts of radix glehniae, 75 parts of Cynanchum glaucescens, 75 parts of the capsule of weeping forsythia, 50 parts of Oroxylum indicum, 50 parts of stiff silkworm, 75 parts of perilla seed, 75 parts of the root bark of white mulberry, hundred
75 parts of portion, 75 parts of tussilago, 75 parts of cape jasmine.
The present invention is also claimed the Chinese medicine preparation being made using above-mentioned Chinese medicine composition.
Further, the Chinese medicine preparation is powder.
The present invention is also claimed the preparation method of above-mentioned Chinese medicine preparation, is to be ground into carefully each taste Chinese medicine of formula ratio
Powder, crosses No. 5 sieves, then through ultramicro grinding, crosses No. 6 sieves, medicinal powder is well mixed and is obtained final product.
The present invention is also claimed above-mentioned Chinese medicine composition and is preparing the medicine for the treatment of acute bronchitis, the infection of the upper respiratory tract
Application in thing.
The present invention is also claimed above-mentioned Chinese medicine preparation and is preparing the medicine for the treatment of acute bronchitis, the infection of the upper respiratory tract
In application.
Chinese medicine composition of the invention is on the basis of ancient prescription sangxing decoction, with reference to clinical treatment acute bronchus for many years
The prescription that the scorching, experience of the infection of the upper respiratory tract is drafted.With theory of traditional Chinese medical science cube, treatment acute bronchitis, upper respiratory tract sense
The diseases such as dye.Complete square totally ten four traditional Chinese medicine, is made powder, with original decoction with traditional handicraft（Prescription is in prepared slices of Chinese crude drugs form
Compatibility, the form of Chinese drug taken is boiled with water）It is fast compared to absorbing, be easy to carry, day dose it is relatively low the advantages of.
Mulberry leaf contain flavonoids, alkaloids, polysaccharide, phytosterol, volatile oil, amino acid, vitamin and micro-
The various active chemical composition such as secondary element.Flavone compound in mulberry leaf is natural antioxidant, can remove in human body and surpass
The free radical of oxonium ion, increases and suppresses the effect of atherogenesis with suppression serum lipids；Mulberry leaf polysaccharide composition
Complexity, with obvious hypoglycemic and blood coagulation resisting function；Volatile oil have certain antibechic, antibacterial, sterilization, it is antimicrobial, refresh oneself,
Hypnosis, calmness etc. are acted on.
Semen armeniacae amarae bitter, it is warm in nature, it is apt to sending down abnormally ascending, its antiasthmatic-antitussive effect reliability.Amarogentin is in traditional Chinese medicine semen armeniacae amarae
One of active ingredient, be conventional expelling phlegm and arresting coughing agent, complementary anticarcinogen, it is fine with antiatherosclerosis, anti-renal interstitial
The medicines such as dimensionization, pulmonary fibrosis resistant, anti-hyperoxia induction injury of lungs, immunosupress, immunological regulation, antitumor, anti-inflammatory and antiulcer
Reason is acted on.
Balloonflower root is relieving cough and reducing sputum one of the Chinese medicine of relievining asthma commonly used on tcm clinical practice, and balloonflower root nature and flavor toil is put down, and has facilitaing lung, profit
The effect of pharynx, eliminating the phlegm, apocenosis.For treating coughing with a lot of sputum, abscess of throat, lung carbuncle is spat, and breathes heavily the diseases such as anxious fullness sensation in chest, dysentery stomachache.
Modern study shows that balloonflower root and its principle active component platycodin have anti-inflammatory analgesic, kobadrin, anti-oxidant, liver protection, town
Quiet, hypoglycemic, improvement Insulin Resistance, reducing blood lipid, cholinolytic, expansion of blood vessels, Spermicide in vitro, antitumor and immunological regulation
The multiple pharmacological effects such as activity, promotion cholic acid are secreted, antiallergy.
Radix glehniae has antipyretic, analgesia, antibechic, eliminating the phlegm, anti-oxidant, cardiac stimulant, anti-mutation, anti-promoting and antitumor, antibacterial
And antimycotic, tyrosinase inhibitory action, regulation immune system, the generation of suppression thromboxane A2 and promotion prostacyclin generation
Etc. multiple pharmacological effect, the active component of the plant mainly has the compositions such as cumarin, carbene, glycosides, polysaccharide, organic acid
The pharmacological action of Cynanchum glaucescens mainly has：Antibechic, eliminating the phlegm and antiinflammatory action：The alcohol extract of rhizoma et radix cynanchi stauntoni and leaves of Daphne genkwa Cynanchum glaucescens
And ether extract has obvious antitussive effect to the mouse cough that concentrated ammonia liquor induces, leaves of Daphne genkwa Cynanchum glaucescens water extract also has antibechic to make
With；Both have phlegm-dispelling functions at alcohol extract, water extract and rhizoma et radix cynanchi stauntoni ether extract.Cynanchum glaucescens in the present invention is rhizoma et radix cynanchi stauntoni and Yuan
One or two in floral leaf Cynanchum glaucescens.
The pharmacological activity of the capsule of weeping forsythia mainly has：It is anti-oxidant（Damaged such as effect of scavenging radical, oxidation-resisting and caducity effect, to oxidation
The protective effect of wound, suppression LDL oxidation effect）, reducing blood lipid, fat-reducing, liver protection, anti-inflammatory, antibacterial, it is antipyretic, removing toxic substances,
Suppress Nasopharyngeal neoplasms and blood vessel source nucleus formation, suppression antiviral, to elastoser, suppress platelet activating factor
Activity, the effect for suppressing di-phosphate ester enzyme activity（Experiment in vitro shows that benzyl carbinol glycoside and lignanoids in the capsule of weeping forsythia have suppression
The effect of cAMP di-phosphate esters enzyme activity processed）And the influence to cardiovascular system.
Oroxylum indicum has antibechic and phlegm-dispelling functions, cure mainly with cough for the infection of the upper respiratory tract of primary symptom, acute bronchitis,
The diseases such as chronic pharyngitis, pneumonia later stage, modern medicine study show Oroxylum indicum have analgesia, anti-inflammatory, antibacterial, anti-mutagenesis, it is anti-oxidant,
Suppress the multiple pharmacological effects such as virus and tumour growth.Its seed also contains scutelloside and Chrysin, and scutelloside has heat-clearing
The pharmacological actions such as removing toxic substances, antibacterial anti-inflammatory, chelating metal ion, step-down, antiallergic action and removing superoxide anion.Oroxylum indicum is planted
Thing has antibacterial activity, and it is to hay bacillus, staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, aspergillus fumigatus, aspergillus flavus etc.
The all active inhibitory action of various bacteria and fungi.
Stiff silkworm it is main by protein, it is enzyme, ammonium oxalate, fat, organic acid, toxin, pigment, volatile oil, vitamin, micro
Element and a small amount of nucleic acid composition, the ammonium oxalate that wherein surface is contained is its main pharmacological components, and the albumen in stiff silkworm is stiff silkworm
Main constituents, have the adrenocortical effect of stimulation.Quercetin in stiff silkworm has preferable eliminating the phlegm, antitussive action,
And have certain antiasthmatic effect, in addition with the capillary resistance that reduces blood pressure, strengthens, reduce capillary fragility, drop blood
Fat, coronary artery dilator, increase the effect such as CF；Ammonium oxalate in stiff silkworm is the generation after muscardine infected silkworm larva
Thank to product, with anticonvulsion and blood coagulation resisting function, endogenous, extrinsic coagulation process are started stiff silkworm and fibrin ferment all has suppression
Make and use, with the effect similar to low molecular weight heparin.
The chemical composition of perilla seed is mainly fat oil, amino acid, trace element etc..Perilla seed have certain antibechic,
Eliminating the phlegm and antiasthmatic effect, its antibechic composition relatively disperse.Perilla seed water extract, alcohol extract show that degree is different with ether extract
Antitussive effect.The small dose group of perilla seed and roasted perilla fruit water extract has good phlegm-dispelling functions.Roasted perilla fruit water extract and
The small dose group of ether extract all shows significant antiasthmatic effect, and the water solubility of composition of relievining asthma is big.It is present in the flat of roasted perilla fruit
Composition its polarity relatively dispersion is breathed heavily, had both been present in the big part of polarity and has been existed in the small part of polarity.Pharmacological research shows purple perilla
Son has reducing blood lipid, promotes the effect such as ability of learning and memory, anti-aging, relieving cough and asthma, antiallergy.
Root bark of white mulberry main chemical compositions are flavone compound, mulberry color furans, umbelliferone, Scopoletin, mulberry glucoproteid
The compositions such as the acetylcholine analog of A, chitin, shitosan and tool antihypertensive effect.The root bark of white mulberry is that clinically conventional cough-relieving is put down
Chinese medicine is breathed heavily, with removing heat from lung and relieving asthma, inducing diuresis for removing edema function, for dyspnea and cough due to lung-heat, oedema turgor oliguria, appearance skin edema.Sang Bai
The volatile oil of skin has activated lymphocyte, improves the effect of body's immunity；Root bark of white mulberry flavonoids have town
Cough, eliminating the phlegm and antiasthmatic effect, antidiabetic effect, antivirus action, antiinflammatory action, also there is anticancer, anti-arachidonic in addition
The effect such as acid, hypotensive, antibacterial, anti-oxidant, analgesia；Scopolactone is relievingd asthma for the root bark of white mulberry, diuresis active ingredient；Root bark of white mulberry first
The butanol component of alcohol extracting thing shows weak antitussive effect to Thiopental Anesthesia guinea pig intraperitoneal injection.
Pharmacological research shows that Stemona alkaloids have extraordinary antibacterial, treating tuberculosis, lax bronchial smooth muscle and desinsection
Effect of activity and expelling phlegm and arresting coughing.
Tussilago have moistening lung, it is relieving cough and reducing sputum the effects such as, have obvious bronchus spasmolysis, central excitation, respiratory stimulant and
Anti-inflammatory etc. act on, play the role of in addition to cardiovascular system, anti-platelet activating factor, anti-oxidant, analgesia, anti-inflammatory, it is antitumor,
It is relieving cough and reducing sputum, to eye and pupil and the effect to digestive system.Flavonols have obvious pharmacology to cardiovascular system
Effect, is its effective component.Its decoction and ethanol extract have antitussive effect, and vinyl alcohol extract has phlegm-dispelling functions, and ether is carried
Take thing and slightly have bronchiectatic activity in a small amount, alcohol, ether extract have respiratory stimulant to act on, ether extract and decoction have liter blood pressure to make
With；Other ether extract can suppress gastrointestinal smooth muscle, there is spasmolysis；Extract and tussilago have antiplatelet activity factor
Effect.
Pharmaceutical research shows, cape jasmine have to liver, brain tissue, pancreatic cell protective effect, bile can be promoted
Secretion, regulation stomach function, increase SBF, repair orthopedic soft tissues and damage, and anti-inflammatory and antalgic, antipyretic, lidan liver,
It is antiviral, antibacterial, antitumor, radiation protection, antiallergy, anti-oxidant, reducing blood lipid, calmness, step-down, antiatherosclerosis, anti-
Asthma, cooling blood and hemostasis etc. are acted on.Cape jasmine health product and various processed products have preferable refrigeration function, and processing is better than with health product effect
Product；Cape jasmine has moderate strength to staphylococcus aureus, hemolytic streptococcus, micrococcus catarrhalis, corynebacterium diphtheriae, tubercle bacillus etc.
Antibacterial action.
Fritillaria thunbergii principle active component is alkaloid and saponin(e, and various western black false hellebore alkaline sterols are contained in Bulbs of Fritillaria thunbergii Miq
Alkaloid：Peimine, Dihydroverticinone, verticinone, Peimine glycosides, Peimine nitrogen oxides, verticinone nitrogen oxygen
Compound, shellfish establish alkali, different Bei Moding alkali, fritillaria piperazine, Zhebeinine etc..Content peimine higher, dehydrogenation Zhejiang shellfish in fritillaria thunbergii
Female alkali, Zhebeinine etc. with kobadrin, are relievingd asthma, calm, analgesia, excited uterus muscle, shunk into belonging to different steroid alkaloid
The effects such as myenteron, suppression heart, hypotensive, blood glucose increasing.
Chinese medicine composition of the invention is ventilatingd the lung and resolving phlegm to treat big method with clearing heat and detoxicating.Fang Zhongyong mulberry leaf relieving the exterior syndromes with drugs pungent in flavor and cool in property, dredge
Dissipate wind-heat, clearing away the lungheat and moisturizing；The bitter gentle drop of almond, moistens the lung and relieve the cough, and two medicines collaboration dispelling wind moistens the lung and relieve the cough and is combined into monarch drug in a prescription.The pungent scattered hardship of balloonflower root
Let out, specially enter lung channel, there is the title of " all medicine ships ", can carry that medicine is up, there is balloonflower root special targeting to act on to PUD D,
There are out facilitaing lung gas, the work(of preventing phlegm from forming and stopping coughing；Fritillaria thunbergii clearing and dissipating phlegm-heat, principal drug assistance moistens the lung and relieve the cough；Radix glehniae is moistened the lung and relieve the cough, heat-clearing life
Tianjin；The sharp lung qi of Cynanchum glaucescens a surname, preventing phlegm from forming and stopping coughing；The capsule of weeping forsythia is clearing heat and detoxicating, and saturating table is dissipated clearly；Oroxylum indicum, stiff silkworm dispelling wind and heat from the body, reducing phlegm and resolving masses,
Removing toxic substances relieving sore-throat；Perilla seed, root bark of white mulberry removing heat from lung and relieving asthma；The tuber of stemona moistens the lung and relieve the cough；Tussilago moistening lung gas, relieving cough and reducing sputum, all medicines of the above
It is altogether ministerial drug to be shared, and lung qi is let out to drop, relieving cough and asthma；The clear purging the lung of pathogenic fire heat of cape jasmine is adjutant, and all medicine compatibilities, the scorching of lung gold is able to clearly
Profit, the superinverse of lung qi is able to respectful drop, and viscid thick phlegm is dissolved, then all diseases of dry-heat impairing lung play moistening for dryness and clearing away heat, resolving sputum altogether from removing
Dissolving stasis, relieving cough and asthma work(.
Chinese medicine composition of the invention is according to traditional Chinese medical theory prescription, using traditional handicraft --- powder is prepared, in system
Agent process for preparation does not have to make a medicine material base change that disease is treated in former prescription, and this preparation original prescription --- soup
Agent is applied up to more than 5 years in our hospital, with good curative effect.Early stage we to Clinical practice Chinese medicine composition of the invention
（Powder）Patient carried out clinical observation, patients with clinical manifestations is the few phlegm of dry cough, and phlegm is difficult to bring up, Se Bai or Huang, pharynx itch or
There is the sense of discomfort, or have uncomfortable in chest losing heart.Chinese medicine composition of the invention by oral administration（Powder）Treatment, cures 30, accounts for 78.9%；
Take a turn for the better 6, account for 15.8%；Not more 2, account for 5.3%.Total effective rate is 94.7%.
According to clinical verification, the Chinese medicine composition that prepared by the present invention can declare clearly scorching, moisten the lung and relieve the cough, resolving sputum and relieving asthma.For
Treatment dryness evil hinders the cough caused by lung, and heating is uncomfortable in chest, headache, thirsty, dry throat nasal cavity dryness；Acute bronchitis, the infection of the upper respiratory tract
See above-mentioned disease person.The instructions of taking of powder is：Boiling water is taken after mixing it with water, a 6~9g, 2~3 times on the one.
Specific embodiment
Following embodiment facilitates a better understanding of the present invention, but does not limit the present invention.Experiment in following embodiments
Method, unless otherwise specified, is conventional method.
Embodiment 1
Provided by the present invention for treating the Chinese medicine composition of acute bronchitis, the infection of the upper respiratory tract by following weight portion
Each bulk drug composition：
40 parts of mulberry leaf, 40 parts of semen armeniacae amarae, 50 parts of balloonflower root, 50 parts of fritillaria thunbergii, 50 parts of radix glehniae, 30 parts of Cynanchum glaucescens, 30 parts of the capsule of weeping forsythia,
30 parts of Oroxylum indicum, 30 parts of stiff silkworm, 30 parts of perilla seed, 50 parts of the root bark of white mulberry, 50 parts of the tuber of stemona, 50 parts of tussilago, 50 parts of cape jasmine.
The taste Chinese medicine of the above 14 is ground into fine powder, crosses No. 5 sieves, then through ultramicro grinding, crosses No. 6 sieves, and medicinal powder is well mixed,
Load Medicinal composite film, per packed 9g, be made powder.
Embodiment 2
Provided by the present invention for treating the Chinese medicine composition of acute bronchitis, the infection of the upper respiratory tract by following weight portion
Each bulk drug composition：
90 parts of mulberry leaf, 60 parts of semen armeniacae amarae, 90 parts of balloonflower root, 90 parts of fritillaria thunbergii, 60 parts of radix glehniae, 90 parts of Cynanchum glaucescens, 60 parts of the capsule of weeping forsythia,
60 parts of Oroxylum indicum, 40 parts of stiff silkworm, 40 parts of perilla seed, 40 parts of the root bark of white mulberry, 40 parts of the tuber of stemona, 40 parts of tussilago, 40 parts of cape jasmine.
The taste Chinese medicine of the above 14 is ground into fine powder, crosses No. 5 sieves, then through ultramicro grinding, crosses No. 6 sieves, and medicinal powder is well mixed,
Load Medicinal composite film, per packed 9g, be made powder.
Embodiment 3
Provided by the present invention for treating the Chinese medicine composition of acute bronchitis, the infection of the upper respiratory tract by following weight portion
Each bulk drug composition：
60 parts of mulberry leaf, 90 parts of semen armeniacae amarae, 40 parts of balloonflower root, 30 parts of fritillaria thunbergii, 90 parts of radix glehniae, 60 parts of Cynanchum glaucescens, 90 parts of the capsule of weeping forsythia,
50 parts of Oroxylum indicum, 60 parts of stiff silkworm, 90 parts of perilla seed, 90 parts of the root bark of white mulberry, 90 parts of the tuber of stemona, 90 parts of tussilago, 90 parts of cape jasmine.
The taste Chinese medicine of the above 14 is ground into fine powder, crosses No. 5 sieves, then through ultramicro grinding, crosses No. 6 sieves, and medicinal powder is well mixed,
Load Medicinal composite film, per packed 9g, be made powder.
Through experiment, any Chinese medicine preparation cure rates for preparing of Application Example 1-3 account for 55.4%, and improvement accounts for 25.6%,
21% more is not accounted for, total effective rate is 79%.
Embodiment 4
Provided by the present invention for treating the Chinese medicine composition of acute bronchitis, the infection of the upper respiratory tract by following weight portion
Each bulk drug composition：
60 parts of mulberry leaf, 60 parts of semen armeniacae amarae, 60 parts of balloonflower root, 60 parts of fritillaria thunbergii, 60 parts of radix glehniae, 60 parts of Cynanchum glaucescens, 60 parts of the capsule of weeping forsythia,
35 parts of Oroxylum indicum, 35 parts of stiff silkworm, 60 parts of perilla seed, 70 parts of the root bark of white mulberry, 70 parts of the tuber of stemona, 70 parts of tussilago, 70 parts of cape jasmine.
The taste Chinese medicine of the above 14 is ground into fine powder, crosses No. 5 sieves, then through ultramicro grinding, crosses No. 6 sieves, and medicinal powder is well mixed,
Load Medicinal composite film, per packed 9g, be made powder.
Embodiment 5
Provided by the present invention for treating the Chinese medicine composition of acute bronchitis, the infection of the upper respiratory tract by following weight portion
Each bulk drug composition：
90 parts of mulberry leaf, 90 parts of semen armeniacae amarae, 90 parts of balloonflower root, 80 parts of fritillaria thunbergii, 80 parts of radix glehniae, 80 parts of Cynanchum glaucescens, 80 parts of the capsule of weeping forsythia,
50 parts of Oroxylum indicum, 50 parts of stiff silkworm, 90 parts of perilla seed, 70 parts of the root bark of white mulberry, 70 parts of the tuber of stemona, 70 parts of tussilago, 70 parts of cape jasmine.
The taste Chinese medicine of the above 14 is ground into fine powder, crosses No. 5 sieves, then through ultramicro grinding, crosses No. 6 sieves, and medicinal powder is well mixed,
Load Medicinal composite film, per packed 9g, be made powder.
Embodiment 6
Provided by the present invention for treating the Chinese medicine composition of acute bronchitis, the infection of the upper respiratory tract by following weight portion
Each bulk drug composition：
70 parts of mulberry leaf, 60 parts of semen armeniacae amarae, 70 parts of balloonflower root, 70 parts of fritillaria thunbergii, 70 parts of radix glehniae, 70 parts of Cynanchum glaucescens, 60 parts of the capsule of weeping forsythia,
30 parts of Oroxylum indicum, 30 parts of stiff silkworm, 60 parts of perilla seed, 60 parts of the root bark of white mulberry, 60 parts of the tuber of stemona, 60 parts of tussilago, 60 parts of cape jasmine.
The taste Chinese medicine of the above 14 is ground into fine powder, crosses No. 5 sieves, then through ultramicro grinding, crosses No. 6 sieves, and medicinal powder is well mixed,
Load Medicinal composite film, per packed 9g, be made powder.
Through experiment, any Chinese medicine preparation cure rates for preparing of Application Example 4-6 account for 58.5%, and improvement accounts for 26%, not
More 15.5% is accounted for, total effective rate is 84.5%.
Embodiment 7
Provided by the present invention for treating the Chinese medicine composition of acute bronchitis, the infection of the upper respiratory tract by following weight portion
Each bulk drug composition：
Mulberry leaf 75g, semen armeniacae amarae 75g, balloonflower root 75g, fritillaria thunbergii 75g, radix glehniae 75g, Cynanchum glaucescens 75g, capsule of weeping forsythia 75g, Oroxylum indicum
50g, stiff silkworm 50g, perilla seed 75g, root bark of white mulberry 75g, tuber of stemona 75g, tussilago 75g, cape jasmine 75g.
The taste Chinese medicine of the above 14 is ground into fine powder, crosses No. 5 sieves, then through ultramicro grinding, crosses No. 6 sieves, and medicinal powder is well mixed,
Load Medicinal composite film, per packed 9g, be made powder.
Through experiment, the Chinese medicine preparation cure rate that Application Example 7 is prepared accounts for 68.9%, and improvement accounts for 15.8%, does not more account for
15.3%, total effective rate is 84.7%.
The applicant hinders the more card type characteristic distributions of pulmonary type by studying checking Xinjiang region cough patients with dryness evil, passes through
Clinical experience develops Chinese medicine preparation of the invention for many years, for treating acute bronchitis, upper respiratory tract infection.Entirely
Fang Gongshi four traditional Chinese medicines, powder is made with traditional handicraft, the powder compared with original decoction（The Chinese medicinal decoction used with being decocted in water for oral dose
Agent）It is fast with absorbing, be easy to carry, day dose it is relatively low the advantages of.Decoction started in clinical practice in 2001, with definite
Clinical efficacy：The cough and expectoration caused by dryness evil hinders lung can be treated, effective percentage is 80%.For Chinese medicine composition of the invention
（Powder）Clinical efficacy, carried out randomized control study, by outpatient service by the secondary cough of acute upper respiratory infection, without phlegm or
A small amount of white phlegm is coughed, the cough course of disease patient of 3-8 weeks is randomly assigned to treatment group and control group, and treatment group gives Chinese medicine of the invention
Composition（Powder）Treated, control group gives cetirizine piece and treated, the cough of patient is observed in medication after 10 days
Shape is integrated and Chinese medicine syndrome integral, as a result referring to Tables 1 and 2.
It is below using the treatment case of Chinese medicine composition of the invention：
1. there is cough, expectoration, pharynx and itches, dry throat, from morning coughs obvious in patient Wang, man after flu of suffering from cold accidentally, look into pair
Pulmonary respiration sound is thick, swallows red tonsillotome less, and rabat prompting is normal, normal pulmonary function, after taking Chinese medicine preparation of the invention 1 week,
Patient's cough and expectoration mitigates earlier above, swallows dry throat mitigation of itching.
2., there is shortness of breath uncomfortable in chest after being suffered from cold accidentally before 2 days in patient Lee, man, cough, dry cough without phlegm, and dry throat pharynx is itched, and is swallowed
Bitterly, without heating, the red tonsillotome of pharynx is looked into less, double pulmonary respiration sounds are thick, and rabat shows no obvious abnormalities, and takes Chinese medicine preparation of the invention
After one week, patient's dry throat pharyngalgia symptom mitigation, cough mitigates earlier above.
3., there is cough before 3 days without obvious inducement in patient Ma, man, coughed the viscous phlegm of yellow, and amount is few, and matter is viscous to be difficult to bring up, pharynx
Dry pain, without heating, sees the red tonsillotome of pharynx less, and double pulmonary respiration sounds are thick, and rabat shows no obvious abnormalities, and blood routine is normal, gives
After oral 5 days, patient's cough, expectoration mitigates Chinese medicine preparation of the invention earlier above, swallows pharyngalgia of itching and alleviates earlier above.
4. there is cough in patient Deng, female, patient after being suffered from cold accidentally before 3 days, expectoration, amount is few, and color is yellow, and matter is glued, and is difficult to cough up
Go out, dry throat bitterly, without heating, sees the red tonsillotome of pharynx less, and double pulmonary respiration sounds are thick, and rabat shows no obvious abnormalities, and blood routine is normal,
After giving Chinese medicine preparation of the invention oral one week, patient's cough, expectoration mitigates earlier above, swallows pharyngalgia of itching and alleviates earlier above.
5. patient Xu certain, female, patient's nearly January coughs, expectoration, and amount is few, in paroxysmal, dry throat, without heating, occasionally there is blood
Silk, looks into the red tonsillotome of pharynx less, and double pulmonary respiration sounds are slightly thick, and rabat shows no obvious abnormalities, and blood routine is normal, and PFT is pointed out just
Often, after giving Chinese medicine preparation of the invention oral one week, patient's cough, expectoration mitigates earlier above, swallows pharyngalgia of itching and alleviates earlier above.
6. patient Wang, male, and the nearly half a year paroxysmal cough of patient, dry cough without phlegm occasionally has shortness of breath uncomfortable in chest, can delay after rest
Solution, dry throat, without heating, looks into the red tonsillotome of pharynx less, and double pulmonary respiration sounds are slightly thick, and rabat shows no obvious abnormalities, and blood routine is normal, lung
Function prompt obstructive pulmonary dysfunction of ventilation, provocative test is positive, after giving Chinese medicine preparation of the invention oral two weeks, patient's cough
Mitigate, shortness of breath uncomfortable in chest has alleviation, swallow dry throat of itching and alleviate earlier above.
7. patient poplar, male, and cough and expectoration more than ten years of recurrent exerbation uncomfortable in chest, patient carrys out exacerbation of symptoms for nearly one week, phlegm of coughing
It is few, occasionally there is shortness of breath uncomfortable in chest, without heating, look into the red tonsillotome of pharynx less, double pulmonary respiration sounds are thick, and rabat prompting chronic bronchial inflammatory changes
Become, blood routine is normal, PFT prompting obstructive pulmonary dysfunction of ventilation, provocative test is negative, gives Chinese medicine preparation mouthful of the invention
After taking two weeks, patient's cough mitigates, and shortness of breath uncomfortable in chest has alleviation, swallows dry throat of itching and alleviates earlier above.
8. patient Luo, female, occur that cough and expectoration is uncomfortable in chest after being suffered from cold before 1 day, cough phlegm is few, and without heating, pharynx is itched dry throat,
Without pharyngalgia, the red tonsillotome of pharynx is looked into less, double pulmonary respiration sounds are thick, rabat prompting shows no obvious abnormalities, and gives Chinese medicine system of the invention
After oral two weeks of agent, patient's cough mitigates, and swallows dry throat of itching and alleviates earlier above.
9. patient Zhang, female, the nearly January tactical deployment of troops cough of patient, swallow to itch and cough, and cough phlegm is few, occasionally has shortness of breath uncomfortable in chest, not
Can alleviate after breath, symptom is aggravated more than night, without heating, look into the red tonsillotome of pharynx less, double pulmonary respiration sounds are slightly thick, and rabat has no bright
Aobvious abnormal, PFT prompting is normal, and after giving Chinese medicine preparation of the invention oral one week, patient's cough mitigates, and shortness of breath uncomfortable in chest has
Alleviate, swallow dry throat of itching and alleviate earlier above.
10. there is pharynx and itches cough to meet after penetrating odor in patient Wei, man, nearly one week of patient, in paroxysmal, dry cough
Without phlegm, dry throat is felt, occasionally there is uncomfortable in chest, without heating, look into the red tonsillotome of pharynx less, double pulmonary respiration sounds are slightly thick, and rabat has no substantially different
Often, blood routine prompting eosinophil increases, and PFT prompting ventilatory function is normal, and provocative test is positive, gives the present invention
Chinese medicine preparation after oral a week, patient's cough mitigates earlier above, and pharynx dry throat of itching is alleviated earlier above, and symptom uncomfortable in chest has alleviation.
Finally it should be noted that：The preferred embodiments of the present invention are the foregoing is only, are not intended to limit the invention,
Although being described in detail to the present invention with reference to the foregoing embodiments, for a person skilled in the art, it still may be used
Modified with to the technical scheme described in foregoing embodiments, or equivalent is carried out to which part technical characteristic.
All any modification, equivalent substitution and improvements within the spirit and principles in the present invention, made etc., should be included in of the invention
Within protection domain.
Claims (8)
1. a kind of Chinese medicine composition for treating acute bronchitis, the infection of the upper respiratory tract, it is characterised in that：By weight
Counting bulk drug is：Mulberry leaf 30-90 parts, semen armeniacae amarae 30-90 parts, balloonflower root 30-90 parts, fritillaria thunbergii 30-90 parts, radix glehniae 30-90 parts,
Cynanchum glaucescens 30-90 parts, capsule of weeping forsythia 30-90 parts, Oroxylum indicum 30-60 parts, stiff silkworm 30-60 parts, perilla seed 30-90 parts, root bark of white mulberry 30-90
Part, tuber of stemona 30-90 parts, tussilago 30-90 parts, cape jasmine 30-90 parts.
2. Chinese medicine composition according to claim 1, it is characterised in that：Counting bulk drug by weight is：Mulberry leaf 60-90
Part, semen armeniacae amarae 60-90 parts, balloonflower root 60-90 parts, fritillaria thunbergii 60-90 parts, radix glehniae 60-90 parts, Cynanchum glaucescens 60-90 parts, capsule of weeping forsythia 60-
90 parts, Oroxylum indicum 30-50 parts, stiff silkworm 30-50 parts, perilla seed 60-90 parts, root bark of white mulberry 60-90 parts, tuber of stemona 60-90 parts, tussilago
60-90 parts, cape jasmine 60-90 parts.
3. Chinese medicine composition according to claim 2, it is characterised in that：Counting bulk drug by weight is：75 parts of mulberry leaf,
75 parts of semen armeniacae amarae, 75 parts of balloonflower root, 75 parts of fritillaria thunbergii, 75 parts of radix glehniae, 75 parts of Cynanchum glaucescens, 75 parts of the capsule of weeping forsythia, 50 parts of Oroxylum indicum, stiff silkworm 50
Part, 75 parts of perilla seed, 75 parts of the root bark of white mulberry, 75 parts of the tuber of stemona, 75 parts of tussilago, 75 parts of cape jasmine.
4. the Chinese medicine preparation being made using any described Chinese medicine compositions of claim 1-3.
5. Chinese medicine preparation according to claim 4, it is characterised in that：The Chinese medicine preparation is powder.
6. the preparation method of the Chinese medicine preparation described in claim 5, it is characterised in that：Each taste Chinese medicine of formula ratio is ground into carefully
Powder, crosses No. 5 sieves, then through ultramicro grinding, crosses No. 6 sieves, medicinal powder is well mixed and is obtained final product.
7. any described Chinese medicine compositions of claim 1-3 are preparing the medicine for the treatment of acute bronchitis, the infection of the upper respiratory tract
Application in thing.
8. the Chinese medicine preparation described in claim 4 or 5 is in treatment acute bronchitis, the medicine of the infection of the upper respiratory tract is prepared
Using.
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| CN102018843A (en) * | 2010-11-24 | 2011-04-20 | 荣成市新技术应用研究所 | Chinese medicinal composition for treating cough |
| CN103272022A (en) * | 2013-04-25 | 2013-09-04 | 孙胜波 | Traditional Chinese medicine composition for treating cough |
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| CN102018843A (en) * | 2010-11-24 | 2011-04-20 | 荣成市新技术应用研究所 | Chinese medicinal composition for treating cough |
| CN103272022A (en) * | 2013-04-25 | 2013-09-04 | 孙胜波 | Traditional Chinese medicine composition for treating cough |
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| 咳嗽重在治痰临床体会;叶华英;《实用中医药杂志》;20080229;第24卷(第2期);第125页 * |
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