CN104248691A - Medicament for the treatment of prurigo nodularis - Google Patents

Abstract

The invention belongs to the technical field of traditional Chinese medicine, and provides a medicament for the treatment of prurigo nodularis in order to solve the problem of the treatment of prurigo nodularis. The medicament is prepared from Schizonepeta, radix sileris, fructus tribuli, spina gleditsiae, Radix Sophorae Flavescentis, cortex dictam, plantago seed, Rhizoma alismatis, safflower, Chinese angelica, radix paeoniae rubrathe root of common peony, honeysuckle, forsythia and eupolyphaga according to a certain proportion. The above medicines are mixed and decocted with 800 ml of water to obtain a first dosage of 200 ml, and 700 ml of water is added and decocted with the drugs to obtain a second dosage of 200 ml. The medicament should be taken with empty stomach twice a day in the morning and in the evening. Among the above medicines, plantago seed, Rhizoma alismatis, honeysuckle flower and forsythia dehumidify and detoxify; safflower, Chinese angelica, radix paeoniae rubrathe root of common peony and eupolyphaga activate blood circulation to dissipate stasis; Schizonepeta, radix sileris, fructus tribuli, spina gleditsiae, Radix Sophorae Flavescentis and cortex dictam dispell wind and relieve itching; and the above medicines in compatibility play a good synergic effect in the treatment of prurigo nodularis.

Description

A kind of medicine being used for the treatment of prurigo nodularis

Technical field

the present invention relates to a kind of medicine (belonging to technical field of Chinese medicines), particularly relate to a kind of medicine being used for the treatment of prurigo nodularis.

background technology:

prurigo nodularis is the infringement of chronic excipuliform nodositas, betides extremity, stretches side for many with shank.Similar with " prurigo ", " accumulation of intractable damp " of the traditional Chinese medical science.Primary disease is many because accumulateing wet, diseases caused by exogenous pathogenic factor pathogenic wind toxic in body, or sting, and damp pathogenic wind toxic, coalescent skin forms.Primary disease is more common in female middle-aged, and erythra is excipuliform infringement, and acute pruritus, the course of disease is slow, and lingering, the person of disappearing has pigment to leave over.Controlling should based on removing dampness and detoxicating, dispelling wind for relieving itching.

clinical treatment prurigo nodularis is comparatively thorny, and general treatment external skin class unguentum or oral hormone class medicine, cure the symptoms, not the disease, do not reach the object for the treatment of.

summary of the invention:

the present invention, in order to solve the problem for the treatment of prurigo nodularis, provides a kind of medicine being used for the treatment of prurigo nodularis.

technical scheme of the present invention is a kind of medicine for the treatment of prurigo nodularis, is be that raw material is prepared from proportion by the Chinese medicine of following weight:

herba Schizonepetae 10 parts, Radix Saposhnikoviae 10 parts, Fructus Atriplicis Sibiricae 10 parts, Spina Gleditsiae 10 parts, Radix Sophorae Flavescentis 10 parts, Cortex Dictamni 10 parts, Semen Plantaginis 12 parts, Rhizoma Alismatis 10 parts,

6 parts, Flos Carthami, Radix Angelicae Sinensis 10 parts, Radix Paeoniae Rubra 10 parts, Flos Lonicerae 15 parts, Fructus Forsythiae 15 parts, eupolyphaga 10 parts, above-mentioned every part be 1 gram.

can any one made on pharmaceutics take said medicine orally dosage form, the preferred dosage form of the present invention is decoction.

said medicine is mixed latter first dose to add 800 milliliters of decoctings to 200 milliliter by the present invention, and second dose adds 700 milliliters of decoctings to 200 milliliter.

using method is the decoction oral that will decoct, every day twice, sooner or later empty clothes.

the traditional Chinese medical science thinks that treatment prurigo nodularis should be antipruritic for Therapeutic Principle with removing dampness and detoxicating, activating blood circulation to dissipate blood stasis, dispelling wind.Semen Plantaginis, Rhizoma Alismatis, Flos Lonicerae, Fructus Forsythiae removing dampness and detoxicating in side of the present invention; Flos Carthami, Radix Angelicae Sinensis, Radix Paeoniae Rubra, eupolyphaga activating blood circulation to dissipate blood stasis; Herba Schizonepetae, Radix Saposhnikoviae, Fructus Atriplicis Sibiricae, Spina Gleditsiae, Radix Sophorae Flavescentis, Cortex Dictamni dispelling wind are antipruritic; Said medicine compatibility uses, synergism, thus the object reaching treatment.

medicine instant effect of the present invention, good effect, has good therapeutic effect to prurigo nodularis.

for proving clinical efficacy and the safety of medicine of the present invention further.69 routine patients are selected to carry out clinical observation to medicine of the present invention.

in example patient, within 15 days, be a course for the treatment of, one the course for the treatment of cured person 20 example, two the course for the treatment of cured person 21 example, two courses for the treatment of above cured person 26 example, invalid 2 examples.Whole use the present invention treats, every day potion, every day twice, sooner or later empty clothes.

criterion of therapeutical effect: effective: chronic excipuliform nodositas infringement, acute pruritus transference cure; Effective: chronic excipuliform nodositas infringement, acute pruritus symptom alleviate or disappear; Invalid: without significant change.

rear curative effect statistical result treated by table 1

Patient	Number of cases	Effective (%)	Effectively (%)	Invalid (%)	Total effective rate (%)
						One the course for the treatment of cured person	20	18(90)	2(10)	0(0)	20(100)
Two the course for the treatment of cured person	21	15(71.4)	6(29.6)	0(0)	21(100)
						Two the course for the treatment of above cured person	28	12(42.3)	14(50)	2(7.7)	26(92.3)
Amount to	69	45(65.2)	22(31.9)	2(2.9)	67(97.1)

model case:

beam, man, 59 years old, the first visit on the 16th of calendar year 2001 JIUYUE.Repeatedly play erythra over nearly 1 year, play is itched, and once examines as " prurigo nodularis " in certain hospital, the multiple hormones ointment of oral antipruritic medicament external, all without obvious curative effects, touchingly not to heal.

indagation: extremity are stretched side and are dispersed in excipuliform Semen Glycines greater tubercle, in bronzing, most of tuberosity top exfoliation, perinodal skin pruritus has lichen sample to change.Dark tongue quality, white and thin fur.

western medicine diagnose: prurigo nodularis.

tcm diagnosis: accumulation of intractable damp.

dialectical treatment: removing dampness and detoxicating, activating blood circulation to dissipate blood stasis, dispelling wind are antipruritic.

herba Schizonepetae 10 parts, Radix Saposhnikoviae 10 parts, Fructus Atriplicis Sibiricae 10 parts, Spina Gleditsiae 10 parts, Radix Sophorae Flavescentis 10 parts, Cortex Dictamni 10 parts, Semen Plantaginis 12 parts, Rhizoma Alismatis 10 parts,

6 parts, Flos Carthami, Radix Angelicae Sinensis 10 parts, Radix Paeoniae Rubra 10 parts, Flos Lonicerae 15 parts, Fructus Forsythiae 15 parts, eupolyphaga 10 parts, above-mentioned every part be 1 gram.

the present invention be said medicine is mixed rear first dose with 800 milliliters of decoctings to 200 milliliter, second dose with 700 milliliters of decoctings to 200 milliliter, every day twice, sooner or later empty clothes.

take 15 doses.

two examine: 15 doses, clothes top, pruritus obviously alleviates, and continues to take medicine.

herba Schizonepetae 10 parts, Radix Saposhnikoviae 10 parts, Fructus Atriplicis Sibiricae 10 parts, Spina Gleditsiae 10 parts, Radix Sophorae Flavescentis 10 parts, Cortex Dictamni 10 parts, Semen Plantaginis 12 parts, Rhizoma Alismatis 10 parts,

6 parts, Flos Carthami, Radix Angelicae Sinensis 10 parts, Radix Paeoniae Rubra 10 parts, Flos Lonicerae 15 parts, Fructus Forsythiae 15 parts, eupolyphaga 10 parts, above-mentioned every part be 1 gram.

the present invention be said medicine is mixed rear first dose with 800 milliliters of decoctings to 200 milliliter, second dose with 700 milliliters of decoctings to 200 milliliter, every day twice, sooner or later empty clothes.

take 15 doses.

three examine: 15 doses, clothes top, most of tuberosity disappears, and does not substantially itch.Continue to take medicine.

herba Schizonepetae 10 parts, Radix Saposhnikoviae 10 parts, Fructus Atriplicis Sibiricae 10 parts, Spina Gleditsiae 10 parts, Radix Sophorae Flavescentis 10 parts, Cortex Dictamni 10 parts, Semen Plantaginis 12 parts, Rhizoma Alismatis 10 parts,

6 parts, Flos Carthami, Radix Angelicae Sinensis 10 parts, Radix Paeoniae Rubra 10 parts, Flos Lonicerae 15 parts, Fructus Forsythiae 15 parts, eupolyphaga 10 parts, above-mentioned every part be 1 gram.

the present invention be said medicine is mixed rear first dose with 800 milliliters of decoctings to 200 milliliter, second dose with 700 milliliters of decoctings to 200 milliliter, every day twice, sooner or later empty clothes.

take 15 doses.

the four diagnostic methods: 15 doses, clothes top, erythra disappears entirely, clinical cure.

detailed description of the invention:

herba Schizonepetae 10 parts, Radix Saposhnikoviae 10 parts, Fructus Atriplicis Sibiricae 10 parts, Spina Gleditsiae 10 parts, Radix Sophorae Flavescentis 10 parts, Cortex Dictamni 10 parts, Semen Plantaginis 12 parts, Rhizoma Alismatis 10 parts,

6 parts, Flos Carthami, Radix Angelicae Sinensis 10 parts, Radix Paeoniae Rubra 10 parts, Flos Lonicerae 15 parts, Fructus Forsythiae 15 parts, eupolyphaga 10 parts, above-mentioned every part be 1 gram.

the present invention be said medicine is mixed rear first dose with 800 milliliters of decoctings to 200 milliliter, second dose with 700 milliliters of decoctings to 200 milliliter, every day twice, sooner or later empty clothes.

Claims (2)

1. being used for the treatment of a medicine for prurigo nodularis, it is characterized in that, is be made up of the medicine of following weight:

Herba Schizonepetae 10 parts, Radix Saposhnikoviae 10 parts, Fructus Atriplicis Sibiricae 10 parts, Spina Gleditsiae 10 parts, Radix Sophorae Flavescentis 10 parts, Cortex Dictamni 10 parts, Semen Plantaginis 12 parts, Rhizoma Alismatis 10 parts,

6 parts, Flos Carthami, Radix Angelicae Sinensis 10 parts, Radix Paeoniae Rubra 10 parts, Flos Lonicerae 15 parts, Fructus Forsythiae 15 parts, eupolyphaga 10 parts, above-mentioned every part be 1 gram.

2. a kind of medicine being used for the treatment of prurigo nodularis according to claim 1, is characterized in that decocting into decoction oral by after described medicament mixed.