CN104248674A - Traditional Chinese medicine for treating burns and scalds - Google Patents

Abstract

The invention relates to a medicament for treating burns and scalds, and in particular relates to a traditional Chinese medicine in which plant Chinese herbs serve as raw materials. The traditional Chinese medicine is characterized by consisting of the following traditional Chinese medicinal raw materials by weight: 13-19 g of angelica sinensis, 13-19 g of red paeonia, 5-15 g of radix angelicae tuhuo, 5-15 g of golden cypress, 13-19 g of cape jasmine, 13-19 g of honeysuckles and 3-9 g of raw liquorice. All the components of the traditional Chinese medicine are natural traditional Chinese medicinal raw materials and are easy to mix; the medicinal herb resources are readily available, and the cost is low. Under the pharmacological function of the traditional Chinese medicines, the traditional Chinese medicine has the effects of clearing away heat and toxin, cooling and activating blood, tonifying spleen, benefiting qi, stopping ache, discharging pus and the like, and can effectively treat burns and scalds by clearing away heat and toxin and performing antiseptic bacteriostasis and defervesce and eliminating steam.

Description

A kind of Chinese medicine for the treatment of burn and scald

Technical field

The present invention relates to the medicine for the treatment of burn and scald, especially a kind of take vegetable Chinese herbal medicine as the Chinese medicine that raw material is made.

Background technology

Burn and scald is the skin acute traumatic disease that thermodynamic activity causes in human body.Primary disease sprinkles burn etc. also known as burn due to hot liquid or fire, fire burn, soup.Be characterized in it being the lighter's only skin and flesh damage, severe one, not only skin and flesh damage, and fire-toxin is flourishing, injures cloudy liquid in body, or invades nutrient blood, inside fire attack internal organs, so that internal organs are become estranged, imbalance between YIN and YANG, deteriorated case is a lot of, very then threat to life.Burn and scald, by the degree of depth, is generally divided into three degree: once burn and scald only injured epidermal area, injured skin rubefaction, swelling, feels smartly bitterly, but anhydrous bubbling out shows; Two degree of burn and scald injure skin corium, and local is red and swollen, heating, and hurt like hell, has obvious blister; Three degree of burn and scald full thickness skin fat, bone and muscle comprised below skin are all subject to imitative evil, and skin is burned black, downright bad, and at this moment pain is inviolent on the contrary, because many nerves are also damaged all together;

At present, the Therapeutic Method of burn and scald is mainly treated according to the degree of burn, as the second degree burn of small size, the complete person of blister, povidone iodine etc. can be coated with on surface, then liquid in sucking-off bubble, wrapped up, the second degree burn of larger area, blister is complete, or the broken person of the blister of small size, cut off blister epidermis, then ointment for external application for curing burn, or with the Chinese medicine and western medicine medicinal liquid of other bacterium processed, make drug adhesion in wound surface with monolayer paraffin oil gauze or medicinal liquid gauze, wound surface exposure or wrapping etc., these Therapeutic Method can only take stopgap measures, and can not effect a permanent cure, often do not reach effect as scheduled.

Summary of the invention

In order to overcome in prior art the deficiency for the treatment of burn and scald and existing, the invention provides a kind ofly to prepare conveniently, medicine source is wide, cost is low, the Chinese medicine of the treatment burn and scald of evident in efficacy, reliable effect, preventing from scar.

The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine for the treatment of burn and scald, it is characterized in that: its raw material of Chinese medicine and weight proportion are: Radix Angelicae Sinensis 13-19 gram, Radix Paeoniae Rubra 13-19 gram, Radix Angelicae Pubescentis 5-15 gram, Cortex Phellodendri 5-15 gram, Fructus Gardeniae 13-19 gram, Flos Lonicerae 13-19 gram, Radix Glycyrrhizae 3-9 gram.

Pharmacological action

Radix Angelicae Sinensis: sweet in the mouth, pungent, bitter, warm in nature.Return liver, the heart, spleen channel.Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, injury from falling down, ulcer sores etc.Radix Angelicae Sinensis has antiinflammatory and bacteriostatic functions, and body can be helped to reduce capillary permeability, suppresses synthesis or the release of PGE2; Radix Angelicae Sinensis also has cosmetology effect, enriches blood and invigorates blood circulation, anti-hypoxia, conditioner body immunity function, promotes that impaired skin better recovers.

Radix Paeoniae Rubra: bitter in the mouth, is slightly cold.Return Liver Channel.Clearing away heat and cooling blood; Blood circulation promoting and blood stasis dispelling.Cure mainly maculae caused by violent heat pathogen, injury from falling down, carbuncle skin infection is seen, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI etc.

Radix Angelicae Pubescentis: acrid in the mouth, hardship, slightly warm in nature.Return liver, kidney, urinary bladder channel.Expelling wind and dampness, dispersing cold for relieving pain.For anemofrigid-damp arthralgia; Lumbocrural pain; Few cloudy volt wind headache, headache toothache etc.Radix Angelicae Pubescentis has analgesia, calmness, the effect of antimicrobial antiphlogistic.

Cortex Phellodendri: bitter in the mouth, cold in nature.Return kidney, bladder, large intestine channel.Heat clearing and damp drying, eliminating fire and detoxication.Control hematodiarrhoea, have loose bowels, quench one's thirst, jaundice ， flaccidity of feet with lamenness, nocturnal emission, stranguria with turbid discharge, hemorrhoid, have blood in stool, also under leucorrhea, and hectic fever due to YIN-deficiency consumptive fever, conjunctival congestion and swelling pain, aphtha of the mouth and tongue, sore swollen toxin etc.Cortex Phellodendri can the breathing of anti-bacteria and the synthesis of RNA, good inhibitory action is all had to antibacterials such as staphylococcus aureus, clostridium tetani, Streptococcus viridanss, and Cortex Phellodendri can improve the cytophagous function of body, effective inflammation-inhibiting effect, can resist the inflammatory reaction caused by many factors, regulates and improves body microcirculation, promote angiogenesis, diminish inflammation edema, and improve body's immunity, helps body better to recover because of the infringement suffered by burn and scald.

Fructus Gardeniae: bitter in the mouth, cold in nature.GUIXIN, lung, tri-jiao channel.Heat clearing away, pathogenic fire purging, removing heat from blood.Control calentura restlessness of asrhenia type and insomnia, jaundice, gonorrhea, quench one's thirst, conjunctival congestion, pharyngalgia, pathopyretic ulcer, sprain and swell and ache.Fructus Gardeniae decoct has inhibitory action to the antibacterial such as staphylococcus aureus, Bacillus typhi, also has inhibitory action in various degree to various skin fungus.Gardenoside contained by Fructus Gardeniae and hydrolyzate genipin thereof have analgesic activity to body, and Fructus Gardeniae antiinflammatory is antibacterial, and gram help treatment soft tissue injury, helps body to the soft tissue quickly-healing by burn and scald.

Flos Lonicerae: cold in nature, sweet in the mouth, enters lung, the heart, stomach warp, has heat-clearing and toxic substances removing, antiinflammatory, tonify deficiency treat effect of wind, cures mainly disease under distension, epidemic febrile disease heating, the diseases such as pyretic toxicity carbuncle and ulcer and tumor.Flos Lonicerae contains the pharmacological component such as chlorogenic acid, luteolin glycosides, have stronger restraint to the various pathogens such as Hemolytic streptococcus, staphylococcus aureus and upper respiratory tract infection Causative virus etc., in addition also can enhancing immunity, hepatoprotective, antiinflammatory, antipyretic, hemostasis (blood coagulation) etc.

Radix Glycyrrhizae: sweet in the mouth, property is put down.GUIXIN, lung, spleen, stomach warp.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.

The invention has the beneficial effects as follows, each component of Chinese medicine of the present invention all adopts natural raw material of Chinese medicine, and its configuration is simple, and medicine source is wide, cost is low.This herbal medicine efficacy synergism, has heat-clearing and toxic substances removing, cooling blood for hemostasis, invigorating the spleen and replenishing QI, relieving spasm to stop pain, the effects such as evacuation of pus, and by the heat-clearing and toxic substances removing to burn and scald, bactericidal, bringing down a fever except steaming, effectively treating burn and scald.

Pharmacodynamics test

Burn and scald model: choose 30 SD rats, after employing 1% pentobarbital sodium (30mg/kg) intraperitoneal injection of anesthesia, takes off back wool, and scalds 8s in 80 DEG C of water-baths, and the dark II degree circle forming diameter 3cm at SD rat back scalds region.

Therapeutic modality: above-mentioned 30 SD rats are divided into three groups, often organizes 10, with gauze wrapping also sub-cage rearing after medicine-feeding, wherein: experimental group, namely takes Chinese medicine of the present invention; Matched group, takes vitamin AD; Blank group, is left intact.

Administration frequency: 1 day/time; Administration time: 4 weeks.

Observation index:

Wound healing percentage rate=[before (before administration after wound surface area-administration wound surface area)/administration wound surface area] * 100%;

Wound surface area: measure wound surface lengthwise A and grow crosswise B diameter, calculating according to π * A*B/4;

Incrustation natural law and decrustation natural law.

Data analysis:

Table 1: medicine to scald SD rat skin different time healing percentage rate ( ± S, n=10);

Table 2: medicine on the impact of After Scalding In Rat skin healing ( ± S, n=10).

table 1

Table 2

Note: P is experimental group data value of " two sample difference in means other T inspection " compared with matched group, wherein, , S, n be T test variable parameter, for mean, S is standard deviation, and n is test samples number.

Interpretation of result: as seen from Table 1, experimental group has significant difference (P<0.01) compared with blank group; Compared with matched group, do not have significant difference (P>0.05) at the 5th day, other times all have significant difference (P<0.01).As seen from the above, for after-stage in burn and scald treatment, Chinese medicine of the present invention has obvious advantage, and speed of wound healing is very fast, and not easily stays cicatrix.

As seen from Table 2, experimental group is compared with blank group and is had significant difference (P<0.01); Compared with matched group, incrustation natural law does not have significant difference (P>0.05), and decrustation natural law has significant difference (P<0.01).As seen from the above, Chinese medicine of the present invention, in the process for the treatment of burn and scald, can be accelerated the decrustation of wound, and can eliminate swollen tissue, alleviating pain, promotes wound healing.

Clinical data

Physical data: burned patient 265 example, is divided into treatment group and matched group at random.Treatment group 132 example, wherein, man 68 example, female 64 example, age 3-75 year, average 40.5 ± 1.4 years old, I degree burn and scald 42 example, shallow II degree burn and scald 30 example, dark II degree burn and scald 31 example, III degree 29 example; Matched group 133 example, wherein, man 69 example, female 64 example, age 2-66 year, average 40.1 ± 1.6 years old, I degree burn and scald 31 example, shallow II degree burn and scald 34 example, dark II degree burn and scald 40 example, III degree 28 example.Two groups of comparing differences are without significance (P>0.05).

Diagnostic criteria: determine diagnosis according to the diagnostic criteria of burn in " Chinese medical disease Standardization of diagnosis and curative effect " that State Administration of Traditional Chinese Medicine issues.

Therapeutic Method: treatment group takes Chinese medicine of the present invention, every day potion, part is sooner or later taken for twice, within 7 days, is a course for the treatment of; Matched group takes three sub-granules, and Inner Mongol Kai Meng pharmaceutcal corporation, Ltd produces, and one time one bag, three times on the one 7 days is a course for the treatment of.

Curative effect determinate standard: cure, symptom and skin lesion all disappear; Effectively, symptom obviously alleviates the >30% that to go down with skin lesion; Invalid, symptom alleviates or skin lesion disappears <30%.

Therapeutic outcome

Table 3: two groups treat 1 course for the treatment of after wound surface situation compare;

Table 4: treat comparitive study after 1 course for the treatment of for two groups.

table 3

table 4

From table 3, treatment group, at the healing days of dietetic therapy burn and scald, is all better than matched group (P<0.01 or P<0.05) in use moist expose burn ointment; From table 4, the cure rate for the treatment of group and matched group, total effective rate have significant difference (P<0.05).

Clinic Case

Lee, man, 18 years old.Accidentally scalded both feet by boiled water, bubble, decortication, hurt like hell, cannot walk.Go each large out-patient treatment to have no improvement, after take Chinese medicine of the present invention, after 2 days, pain subtracts greatly, and within 7 days, obviously recover afterwards, recover completely after 3 week, both feet have no obvious cicatrix.

Zhang, female, 39 years old.Cooking is accidentally scalded by boiled water, and area reaches 20% of whole body, does not all heal in various big hospital treatment.After take Chinese medicine of the present invention, non-hurt like hell in taking medicine, wound surface all healed after 3 week.Follow up a case by regular visits to half a year, have no scar hyperplasia, skin function recovers good.

Detailed description of the invention

In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.

Embodiment 1

Take Radix Angelicae Sinensis 19 grams, Radix Paeoniae Rubra 19 grams, Radix Angelicae Pubescentis 15 grams, Cortex Phellodendri 15 grams, Fructus Gardeniae 19 grams, Flos Lonicerae 19 grams, Radix Glycyrrhizae 9 grams.Conventionally make Chinese medicine decoction.

Embodiment 2

Preferably take Radix Angelicae Sinensis 16 grams, Radix Paeoniae Rubra 16 grams, Radix Angelicae Pubescentis 10 grams, Cortex Phellodendri 10 grams, Fructus Gardeniae 15 grams, Flos Lonicerae 16 grams, Radix Glycyrrhizae 8 grams.Conventionally make Chinese medicine decoction.

Embodiment 3

Preferably take Radix Angelicae Sinensis 13 grams further, Radix Paeoniae Rubra 13 grams, Radix Angelicae Pubescentis 6 grams, Cortex Phellodendri 6 grams, Fructus Gardeniae 13 grams, Flos Lonicerae 13 grams, Radix Glycyrrhizae 4 grams.Conventionally make Chinese medicine decoction.

After first medicine being washed, with cold water soak 15-20 minute, then medicine is placed in the vessel of marmite, pottery or crock and so on and (cannot iron pan and aluminum pot be used), add water to and do not have powder 5 cm, carry out first time decoction, after boiling with big fire, use instead little fire decoct 20-30 minute all right, medicine soup is poured in vessel, then decocts second time, the method decocting second time is the same with first pass, just boils rear little fire and decocts 15-20 minute.After having decocted, twice decoction is removed slag extracting juice 300-400ml.

Usage: one day potion, is decocted in water for oral dose, patient one natural gift are early, evening takes for twice, for the patient of the difficulty that takes traditional Chinese medicine, can sub-service repeatedly on a small quantity.Within 7 days, be a course for the treatment of, also can join medicine for external use and use.

Claims (4)

1. treat a Chinese medicine for burn and scald, it is characterized in that, its raw material of Chinese medicine and weight proportion are: Radix Angelicae Sinensis 13-19 gram, Radix Paeoniae Rubra 13-19 gram, Radix Angelicae Pubescentis 5-15 gram, Cortex Phellodendri 5-15 gram, Fructus Gardeniae 13-19 gram, Flos Lonicerae 13-19 gram, Radix Glycyrrhizae 3-9 gram.

2. treat the Chinese medicine of burn and scald according to claim 1, it is characterized in that, its raw material of Chinese medicine and weight proportion are: Radix Angelicae Sinensis 19 grams, Radix Paeoniae Rubra 19 grams, Radix Angelicae Pubescentis 15 grams, Cortex Phellodendri 15 grams, Fructus Gardeniae 19 grams, Flos Lonicerae 19 grams, Radix Glycyrrhizae 9 grams.

3. treat the Chinese medicine of burn and scald according to claim 1, it is characterized in that, its raw material of Chinese medicine and weight proportion are: Radix Angelicae Sinensis 16 grams, Radix Paeoniae Rubra 16 grams, Radix Angelicae Pubescentis 10 grams, Cortex Phellodendri 10 grams, Fructus Gardeniae 15 grams, Flos Lonicerae 16 grams, Radix Glycyrrhizae 8 grams.

4. treat the Chinese medicine of burn and scald according to claim 1, it is characterized in that, its raw material of Chinese medicine and weight proportion are: Radix Angelicae Sinensis 13 grams, Radix Paeoniae Rubra 13 grams, Radix Angelicae Pubescentis 6 grams, Cortex Phellodendri 6 grams, Fructus Gardeniae 13 grams, Flos Lonicerae 13 grams, Radix Glycyrrhizae 4 grams.