CN104225387A - Traditional Chinese medicine composition for treating damp-heat blocked type diabetes feet - Google Patents
Traditional Chinese medicine composition for treating damp-heat blocked type diabetes feet Download PDFInfo
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- CN104225387A CN104225387A CN201410460045.7A CN201410460045A CN104225387A CN 104225387 A CN104225387 A CN 104225387A CN 201410460045 A CN201410460045 A CN 201410460045A CN 104225387 A CN104225387 A CN 104225387A
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Abstract
The invention discloses a traditional Chinese medicine composition for treating damp-heat blocked type diabetes feet. The traditional Chinese medicine composition for treating damp-heat blocked type diabetes feet is prepared from the following traditional Chinese medicine raw materials in parts by weight: 10-18 parts of rhizoma atractylodis, 10-18 parts of cortex phellodendri, 10-18 parts of radix achyranthis bidentatae, 22-31 parts of rhizoma smilacis glabrae, 10-18 parts of fructus forsythia, 10-18 parts of manyleaf paris rhizome, 10-18 parts of oriental wormwood, 22-31 parts of phaseolus calcaratus, 22-31 parts of raw pearl barley, 10-18 parts of radix paeoniae rubra, 10-18 parts of angelica sinensis and 22-31 parts of herba lycopi. Most of the raw materials of the traditional Chinese medicine composition have the functions of eliminating dampness and heat, promoting blood circulation and detoxication; the total effective rate is 90.47%; the clinical symptoms can be improved; the treatment course can be shortened.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition and application thereof for the treatment of diabetic foot, particularly relate to a kind of Chinese medicine composition for the treatment of damp and hot accumulation type diabetic foot.
Background technology
Diabetic foot (DF) is one of chronic complicating diseases of diabetes, destroy to Lower Distal Extremities dysautonomia and peripheral angiopathy is relevant in various degree foot ulcers, infection and (or) deep tissues, the lighter show as foot deformity, xerosis cutis and send out cool, callus, foot ulcers, gangrene can be there is in severe one, be the main cause causing diabetics limbs maimed person, drastically influence the quality of life of patient.
Diabetic foot, also known as diabetic gangrene, belongs to the traditional Chinese medical science " necrosis " category together with thromboangiitis obliterans, atherosclerotic occlusive disease.Chinese medicine thinks that this disease is mainly deficiency of both QI and YIN, obstruction of collaterals by blood stasis, and QI and blood can not caused by sensible extremity.But chemical drugs does not also have the special medicine for diabetic foot, general treatment method is conservative symptomatic treatment, and simultaneously conventional chemicals has obvious side effect, and diabetics needs lifelong medication, and long-term prescription can exert an adverse impact to health.
Summary of the invention
For above-mentioned prior art, the invention provides a kind of Chinese medicine composition for the treatment of damp and hot accumulation type diabetic foot, this Chinese medicine composition has eliminating damp-heat, effect of promoting blood circulation and detoxication, and easy to operation.
The present invention is achieved by the following technical solutions:
Treat a Chinese medicine composition for damp and hot accumulation type diabetic foot, be made up of the raw material of Chinese medicine of following weight:
Rhizoma Atractylodis 10 ~ 18 parts, Cortex Phellodendri 10 ~ 18 parts, Radix Achyranthis Bidentatae 10 ~ 18 parts, Rhizoma Smilacis Glabrae 22 ~ 31 parts, Fructus Forsythiae 10 ~ 18 parts, Rhizoma Paridis 10 ~ 18 parts, Herba Artemisiae Scopariae 10 ~ 18 parts, Semen Phaseoli 22 ~ 31 parts, raw Semen Coicis 22 ~ 31 parts, Radix Paeoniae Rubra 10 ~ 18 parts, Radix Angelicae Sinensis 10 ~ 18 parts, Herba Lycopi 22 ~ 31 parts.
Preferably, be made up of the raw material of Chinese medicine of following weight:
Rhizoma Atractylodis 12 parts, Cortex Phellodendri 12 parts, Radix Achyranthis Bidentatae 12 parts, Rhizoma Smilacis Glabrae 26 parts, Fructus Forsythiae 12 parts, Rhizoma Paridis 12 parts, Herba Artemisiae Scopariae 12 parts, Semen Phaseoli 26 parts, raw Semen Coicis 26 parts, Radix Paeoniae Rubra 12 parts, Radix Angelicae Sinensis 12 parts, Herba Lycopi 26 parts.
More preferably, be made up of the raw material of Chinese medicine of following weight:
Rhizoma Atractylodis 15 parts, Cortex Phellodendri 15 parts, Radix Achyranthis Bidentatae 15 parts, Rhizoma Smilacis Glabrae 30 parts, Fructus Forsythiae 15 parts, Rhizoma Paridis 15 parts, Herba Artemisiae Scopariae 15 parts, Semen Phaseoli 30 parts, raw Semen Coicis 30 parts, Radix Paeoniae Rubra 15 parts, Radix Angelicae Sinensis 15 parts, Herba Lycopi 30 parts.
Above-mentioned medical material is put into marmite, adds the water soaking 2 hours of 4 times of dose weight multiples, decoct 1 hour, filter to obtain medicinal liquid and medicinal residues, in medicinal residues, add the water of 2 times of doses again, decoct 0.5 hour, filter to obtain medicinal liquid, merge the medicinal liquid of twice, to obtain final product.
Diabetic foot is one of chronic complicating diseases of diabetes, should belong to the traditional Chinese medical science " arthromyodynia " category according to its clinical manifestation.Damp and hot accumulation type diabetes infect fully or ulcer occurs, local congestion and swelling pain, and the rotten stiff of pus, can accompany low grade fever.White and greasy fur or yellow greasy, slippery and rapid pulse.Be more common in infectious limitation person.Skin ulceration, damp and hot heresy is outer invades, irregularly intermittent pusle of fighting network, therefore sees congestion and swelling pain, and intenseness of heat meat is rotten, thus skin diabrosis, retention of damp-heat in the interior, therefore can low grade fever.White and greasy fur or yellow greasy, slippery and rapid pulse is damp and hot resembling.Raw many tools of the present invention eliminating damp-heat, promoting blood circulation and detoxication effect, total effective rate is 90.47%, can improve clinical symptoms, shortens and treats the course for the treatment of.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated.
Embodiment 1:
Treat a Chinese medicine composition for damp and hot accumulation type diabetic foot, be made up of the raw material of Chinese medicine of following weight proportion:
Rhizoma Atractylodis 10 grams, Cortex Phellodendri 10 grams, Radix Achyranthis Bidentatae 10 grams, Rhizoma Smilacis Glabrae 22 grams, Fructus Forsythiae 10 grams, Rhizoma Paridis 10 grams, Herba Artemisiae Scopariae 10 grams, Semen Phaseoli 22 grams, raw Semen Coicis 22 grams, Radix Paeoniae Rubra 10 grams, Radix Angelicae Sinensis 10 grams, Herba Lycopi 22 grams.
Embodiment 2:
Treat a Chinese medicine composition for damp and hot accumulation type diabetic foot, be made up of the raw material of Chinese medicine of following weight proportion:
Rhizoma Atractylodis 18 grams, Cortex Phellodendri 18 grams, Radix Achyranthis Bidentatae 18 grams, Rhizoma Smilacis Glabrae 31 grams, Fructus Forsythiae 18 grams, Rhizoma Paridis 18 grams, Herba Artemisiae Scopariae 18 grams, Semen Phaseoli 31 grams, raw Semen Coicis 31 grams, Radix Paeoniae Rubra 18 grams, Radix Angelicae Sinensis 18 grams, Herba Lycopi 31 grams.
Embodiment 3:
Treat a Chinese medicine composition for damp and hot accumulation type diabetic foot, be made up of the raw material of Chinese medicine of following weight proportion:
Rhizoma Atractylodis 12 grams, Cortex Phellodendri 12 grams, Radix Achyranthis Bidentatae 12 grams, Rhizoma Smilacis Glabrae 26 grams, Fructus Forsythiae 12 grams, Rhizoma Paridis 12 grams, Herba Artemisiae Scopariae 12 grams, Semen Phaseoli 26 grams, raw Semen Coicis 26 grams, Radix Paeoniae Rubra 12 grams, Radix Angelicae Sinensis 12 grams, Herba Lycopi 26 grams.
Embodiment 4:
Treat a Chinese medicine composition for damp and hot accumulation type diabetic foot, be made up of the raw material of Chinese medicine of following weight proportion:
Rhizoma Atractylodis 15 grams, Cortex Phellodendri 15 grams, Radix Achyranthis Bidentatae 15 grams, Rhizoma Smilacis Glabrae 30 grams, Fructus Forsythiae 15 grams, Rhizoma Paridis 15 grams, Herba Artemisiae Scopariae 15 grams, Semen Phaseoli 30 grams, raw Semen Coicis 30 grams, Radix Paeoniae Rubra 15 grams, Radix Angelicae Sinensis 15 grams, Herba Lycopi 30 grams.
Clinical data
1.1 physical data:
All cases all meets diabetic foot clinical criteria.Clinically divide two groups by random digits table by 81 routine patients, wherein treatment group 42 example, 41 ~ 62 years old age, the course of disease 2 ~ 15 years; Matched group is 39 examples, 40 ~ 69 years old age, course of disease 1-14; Treatment group and matched group patient compare in sex, age, the course of disease, the state of an illness, and no significant difference (P > 0.05), has comparability.
1.2 clinical criterias:
All patients all meets WHO(1999) diabetes diagnostic criterion, damp and hot accumulation type diabetic foot diagnostic criteria: foot infects or ulcer occurs, local congestion and swelling pain, the rotten stiff of pus, can accompany low grade fever.White and greasy fur or yellow greasy, slippery and rapid pulse.
1.3 cases are included in and exclusion standard:
(1) inclusive criteria:
meet WHO(1999) diabetes diagnostic criterion;
meet diabetic foot (Wagner classification 0 grade) diagnostic criteria.(2) exclusion standard:
type 1 diabetes patient;
diabetic foot (Wagner classification) 1 grade and above patient;
the diabetic complication person having other serious.
1.4 Therapeutic Method:
Two groups of patients all carry out diabetes education and appropriate exercise, all should insulinize, control blood sugar level.Wherein, matched group patient gives intravenous drip thioctic acid 450mg/ day (Yabao Group Taiyuan Pharmaceutical Co., Ltd. produces, the accurate word H20055869 of traditional Chinese medicines); Treatment group patient gives the Chinese medicine composition foot bath of the embodiment of the present invention 4 on treatment of control group basis; get every agent medicine in the embodiment of the present invention 4 and decoct twice; extracting juice 200 ~ 300ml altogether; point early, evening twice warmly takes; period in a medicine is avoided eating anything raw or cold, pungent, stimulate and rotten thing; fry, fire are burned and stodgy food should not be eaten more, within two weeks, are a course for the treatment of.
1.5 curative effect determinate standards:
" diabetes (diabetes) traditional Chinese medical science TCM Differentiation of Clinical Stages and efficacy assessment standard " that " the new Chinese medicine guideline of clinical investigations " issued according to Ministry of Health of the People's Republic of China and diabetes Professional Committee of Chinese Chinese medicine association formulate is formulated.
Effective: clinical symptoms is clearly better, foot occurs without infection or ulcer, and without pain numbness sense;
Effective: clinical symptoms takes a turn for the better, ulcer of foot, and other symptoms are slightly improved;
Invalid: symptom has no improvement.
1.6 statistical procedures:
Application SPSS10.0 software carries out statistical procedures, continuous data adopt mean ± standard deviation with
represent, enumeration data adopts
inspection, compare between group and adopt t inspection, P < 0.05 has statistical significance.
2 results
2.1 Clinical efficacy comparisons:
After the course for the treatment of, effective 25 examples for the treatment of group, account for 59.52%, and effective 13 examples, account for 30.95%, invalid 4 examples, and total effective rate is 90.47%; Effective 9 examples of matched group, account for 23.08%, and effective 13 examples, account for 33.33%, invalid 17 examples, and total effective rate is 56.41%; Two groups of total effective rates compare, and difference has statistical significance (P < 0.05).
2.3 untoward reaction:
Untoward reaction is there is in treatment group without patient.
Claims (4)
1. treat a Chinese medicine composition for damp and hot accumulation type diabetic foot, it is characterized in that, be made up of the raw material of Chinese medicine of following weight:
Rhizoma Atractylodis 10 ~ 18 parts, Cortex Phellodendri 10 ~ 18 parts, Radix Achyranthis Bidentatae 10 ~ 18 parts, Rhizoma Smilacis Glabrae 22 ~ 31 parts, Fructus Forsythiae 10 ~ 18 parts, Rhizoma Paridis 10 ~ 18 parts, Herba Artemisiae Scopariae 10 ~ 18 parts, Semen Phaseoli 22 ~ 31 parts, raw Semen Coicis 22 ~ 31 parts, Radix Paeoniae Rubra 10 ~ 18 parts, Radix Angelicae Sinensis 10 ~ 18 parts, Herba Lycopi 22 ~ 31 parts.
2. a kind of Chinese medicine composition for the treatment of damp and hot accumulation type diabetic foot as claimed in claim 1, is characterized in that, be made up of the raw material of Chinese medicine of following weight:
Rhizoma Atractylodis 12 parts, Cortex Phellodendri 12 parts, Radix Achyranthis Bidentatae 12 parts, Rhizoma Smilacis Glabrae 26 parts, Fructus Forsythiae 12 parts, Rhizoma Paridis 12 parts, Herba Artemisiae Scopariae 12 parts, Semen Phaseoli 26 parts, raw Semen Coicis 26 parts, Radix Paeoniae Rubra 12 parts, Radix Angelicae Sinensis 12 parts, Herba Lycopi 26 parts.
3. a kind of Chinese medicine composition for the treatment of damp and hot accumulation type diabetic foot as claimed in claim 1, is characterized in that, be made up of the raw material of Chinese medicine of following weight:
Rhizoma Atractylodis 15 parts, Cortex Phellodendri 15 parts, Radix Achyranthis Bidentatae 15 parts, Rhizoma Smilacis Glabrae 30 parts, Fructus Forsythiae 15 parts, Rhizoma Paridis 15 parts, Herba Artemisiae Scopariae 15 parts, Semen Phaseoli 30 parts, raw Semen Coicis 30 parts, Radix Paeoniae Rubra 15 parts, Radix Angelicae Sinensis 15 parts, Herba Lycopi 30 parts.
4. the Chinese medicine composition described in any one of claim 1-3, it is characterized in that, preparation method is: above-mentioned medical material is put into marmite, adds the water soaking 2 hours of 4 times of dose weight multiples, decocts 1 hour, filter to obtain medicinal liquid and medicinal residues, in medicinal residues, add the water of 2 times of doses again, decoct 0.5 hour, filter to obtain medicinal liquid, merge the medicinal liquid of twice, to obtain final product.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410460045.7A CN104225387A (en) | 2014-09-11 | 2014-09-11 | Traditional Chinese medicine composition for treating damp-heat blocked type diabetes feet |
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| CN201410460045.7A CN104225387A (en) | 2014-09-11 | 2014-09-11 | Traditional Chinese medicine composition for treating damp-heat blocked type diabetes feet |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107582929A (en) * | 2017-10-12 | 2018-01-16 | 李素花 | A kind of bath foot powder and its preparation method and application |
| CN112294928A (en) * | 2020-04-30 | 2021-02-02 | 朱彤 | A Chinese medicinal composition for treating diabetes, and its preparation method |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20010000070A (en) * | 2000-01-11 | 2001-01-05 | 김찬호 | Agents for diabetes and the manufacturing method thereof |
| CN101843738A (en) * | 2009-11-18 | 2010-09-29 | 北京绿源求证科技发展有限责任公司 | Chinese medicament for treating diabetic feet |
-
2014
- 2014-09-11 CN CN201410460045.7A patent/CN104225387A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20010000070A (en) * | 2000-01-11 | 2001-01-05 | 김찬호 | Agents for diabetes and the manufacturing method thereof |
| CN101843738A (en) * | 2009-11-18 | 2010-09-29 | 北京绿源求证科技发展有限责任公司 | Chinese medicament for treating diabetic feet |
Non-Patent Citations (1)
| Title |
|---|
| 刘大芳: "糖尿病足的辩证治疗", 《世界中医药》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107582929A (en) * | 2017-10-12 | 2018-01-16 | 李素花 | A kind of bath foot powder and its preparation method and application |
| CN112294928A (en) * | 2020-04-30 | 2021-02-02 | 朱彤 | A Chinese medicinal composition for treating diabetes, and its preparation method |
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Application publication date: 20141224 |
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