CN104208640A - Traditional Chinese medicine composition for treating delayed menstrual cycle - Google Patents
Traditional Chinese medicine composition for treating delayed menstrual cycle Download PDFInfo
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- CN104208640A CN104208640A CN201410485434.5A CN201410485434A CN104208640A CN 104208640 A CN104208640 A CN 104208640A CN 201410485434 A CN201410485434 A CN 201410485434A CN 104208640 A CN104208640 A CN 104208640A
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Abstract
The invention belongs to the technical field of traditional Chinese medicines and aims at providing a traditional Chinese medicine composition for treating delayed menstrual cycle. The traditional Chinese medicine composition is prepared from the following raw pharmaceutical materials in parts by weight: 15-25 parts of epimedium, 25-35 parts of cortex moutan, 9-15 parts of morinda root, 9-15 parts of nutagrass flatsedge rhizome, 15-25 parts of cassia twig, 25-35 parts of achyranthes root, 15-25 parts of eucommia bark, 9-15 parts of dried ginger, 10-20 parts of peach kernel, 25-35 parts of dipsacus root, 10-20 parts of fleece-flower root, 25-35 parts of mistletoe, 10-20 parts of prepared rehmannia root, 9-15 parts of donkey-hide gelatin, 15-25 parts of dodder seed, 20-30 parts of poria cocos, 3-9 parts of licorice root and 6-12 parts of salvia miltiorrhiza. The traditional Chinese medicine composition provided by the invention has the advantages of durable drug effect, definite treatment effect, high safety, no toxic and side effects and simplicity in medication.
Description
Technical field
The invention belongs to technical field of Chinese medicines, specifically refer to a kind of Chinese medicine composition for the treatment of menstruation and delaying.
Background technology
The menstrual cycle of normal rule is generally no less than 21 days or more than 45 days, within average 28--30 days, is a menstrual cycle, within 21--35 days, is the normal range of menstrual cycle.Delay for menstruation more than more than 35 days persons, being shorter than 21 days persons for menstruation shifts to an earlier date.Menstrual cycle is the important indicator judging female body health, menstruation shifts to an earlier date or delays the category all belonging to menoxenia, abnormal menstrual cycle can cause a series of somatic reaction of women, delay as menstruation can cause that women is depressed, abdominal pain, the easily tired easily symptom such as dry.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition for the treatment of menstruation and delaying.
For realizing above-mentioned technical purpose, the technical solution adopted in the present invention is: a kind of Chinese medicine composition for the treatment of menstruation and delaying, it is characterized in that, this Chinese medicine composition adopts the material medicine of following weight proportion to combine: Herba Epimedii 15-25 part, Cortex Moutan 25-35 part, Radix Morindae Officinalis 9-15 part, Rhizoma Cyperi 9-15 part, Ramulus Cinnamomi 15-25 part, Radix Achyranthis Bidentatae 25-35 part, Cortex Eucommiae 15-25 part, Rhizoma Zingiberis 9-15 part, Semen Persicae 10-20 part, Radix Dipsaci 25-35 part, Radix Polygoni Multiflori 10-20 part, Herba Visci 25-35 part, Radix Rehmanniae Preparata 10-20 part, Colla Corii Asini 9-15 part, Semen Cuscutae 15-25 part, Poria 20-30 part, Radix Glycyrrhizae 3-9 part, Radix Salviae Miltiorrhizae 6-12 part.
Optimum weight part of above-mentioned raw materials medicine is: Herba Epimedii 20 parts, Cortex Moutan 30 parts, Radix Morindae Officinalis 12 parts, Rhizoma Cyperi 12 parts, Ramulus Cinnamomi 20 parts, Radix Achyranthis Bidentatae 30 parts, the Cortex Eucommiae 20 parts, Rhizoma Zingiberis 12 parts, 15 parts, Semen Persicae, Radix Dipsaci 30 parts, the Radix Polygoni Multiflori 15 parts, Herba Visci 30 parts, 15 parts, Radix Rehmanniae Preparata, 12 parts, Colla Corii Asini, Semen Cuscutae 20 parts, 25 parts, Poria, 6 parts, Radix Glycyrrhizae, Radix Salviae Miltiorrhizae 9 parts.
The instructions of taking of Chinese medicine composition provided by the present invention is: adopt the method for conventional fried Chinese medicine to get its medicine juice 300-500ml by after the mixing of the material medicine of above-mentioned weight proportion, every day takes for twice sooner or later, and every day one is secondary.
Prescription analysis: the traditional Chinese medical science is thought, menstruation is delayed because of holding back of wood gas strongly fragrant, and genus closes the machine of knot, and it is former, and always because spleen is wet, liver falls into, and wood gas is strongly fragrant to fall into, and must not develop, and unfavorable through blood clotting silt, wood gas is held back the weak or middle scorched earth of strongly fragrant not outer Liver and kidney and wet and cause.Based on above-mentioned cognition, in this Chinese medicine composition, Herba Epimedii, Radix Morindae Officinalis, Semen Cuscutae kidney invigorating and YANG supporting, Radix Achyranthis Bidentatae, the Cortex Eucommiae, Radix Dipsaci, Herba Visci invigorating the liver and kidney, Rhizoma Zingiberis warming spleen and stomach for dispelling cold, Poria promoting diuresis to eliminate damp pathogen, Ramulus Cinnamomi, Rhizoma Cyperi dispersing the stagnated live-QI to relieve the stagnation of QI, above-mentioned all medicines share, Liver and kidney must be mended, and spleen is positive must answer, and stagnation of liver-QI must be separated.Cortex Moutan, Semen Persicae, Radix Salviae Miltiorrhizae promoting blood circulation to remove blood stasis break the solidifying of menses and become silted up, and the Radix Polygoni Multiflori, Colla Corii Asini, Radix Rehmanniae Preparata are enriched blood YIN nourishing.Share by said medicine, play altogether and separate stagnation of liver-QI, change the solidifying effect of becoming silted up, enriching blood, menstruation is delayed a disease and is explained by oneself.
Beneficial effect of the present invention: Chinese medicine of the present invention has lasting medicine, determined curative effect, safety is high, have no side effect and the simple advantage of medication.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be further described.
Embodiment 1
A kind of Chinese medicine composition for the treatment of menstruation and delaying, it is characterized in that, this Chinese medicine composition adopts the material medicine of following weight proportion to combine: Herba Epimedii 25g, Cortex Moutan 35g, Radix Morindae Officinalis 15g, Rhizoma Cyperi 15g, Ramulus Cinnamomi 25g, Radix Achyranthis Bidentatae 35g, Cortex Eucommiae 25g, Rhizoma Zingiberis 15g, Semen Persicae 20g, Radix Dipsaci 35g, Radix Polygoni Multiflori 20g, Herba Visci 35g, Radix Rehmanniae Preparata 20g, Colla Corii Asini 15g, Semen Cuscutae 25g, Poria 30g, Radix Glycyrrhizae 9g, Radix Salviae Miltiorrhizae 12g.
In the present embodiment, for carrying out toxicity test to medicine, the weight portion of each material medicine is got its maximum weight part and is tested, and toxicity test is divided into acute toxicity testing and long term toxicity test, and result is as follows:
Acute toxicity test: for convenience of carrying out dispensing feeding to white mice, the Chinese medicine decoction embodiment of the present invention 1 prepared carries out concentrated atomization pelletize and obtains Chinese medicinal granule.Chinese medicinal granule is dissolved in distilled water, with 195 of clinical consumption per day times to white mice dispensing feeding, observes 7.The activity of all white mice of result, diet, hair no abnormality seen, have no toxic reaction.Irritation test is carried out to white mouse oral cavity and damaged skin, there are no irritative response and other untoward reaction.
Long term toxicity test: the Chinese medicinal granule prepared in this embodiment of the invention is dissolved in water to mice by 20.15g crude drug/kg, to mice continuous use 16 weeks, every day 2 times, and drug withdrawal is after 2 weeks, result shows: the index such as hair, behavior, defecation, body weight, organ weights, hemogram, hepatic and renal function, blood glucose, blood fat of Chinese medicine of the present invention to test white mice all has no significant effect, and internal organs naked eyes do not find difference change.Employing histological indications shows, medication 16 weeks and drug withdrawal are after 2 weeks, and Organs of Mice is all without obviously changing.
Embodiment 2
A kind of Chinese medicine composition for the treatment of menstruation and delaying, it is characterized in that, this Chinese medicine composition adopts the material medicine of following weight proportion to combine: Herba Epimedii 20g, Cortex Moutan 30g, Radix Morindae Officinalis 12g, Rhizoma Cyperi 12g, Ramulus Cinnamomi 20g, Radix Achyranthis Bidentatae 30g, Cortex Eucommiae 20g, Rhizoma Zingiberis 12g, Semen Persicae 15g, Radix Dipsaci 30g, Radix Polygoni Multiflori 15g, Herba Visci 30g, Radix Rehmanniae Preparata 15g, Colla Corii Asini 12g, Semen Cuscutae 20g, Poria 25g, Radix Glycyrrhizae 6g, Radix Salviae Miltiorrhizae 9g.
In the present embodiment, adopt the material medicine of above-mentioned weight proportion to carry out clinical trial, test as follows:
Through prolonging patient 168 example, the longest menstrual cycle is extended down to 3 months, and the shortest is extended down to 40 days, and average menstrual cycle is 55.35 days.
Treatment standard: shorten to effectively before menstrual cycle compared treatment in continuous 3 months, for curing within continuous 3 month change in menstrual cycle to 35 day.
Treatment means: after each menstruation terminates, take Chinese medicine composition of the present invention continuously 2 weeks, terminate to take after two menstrual cycle, the natural law change of Continuous Observation 3 menstrual cycle.
Result is as follows:
In 168 routine patients, the natural law having the second time menstrual cycle of 139 routine patients to compare previous menstrual cycle after taking end for the first time shortens, and shorten in average natural law is 6.8 days.When terminating after two menstrual cycle to take, the menstrual cycle before having the third time menstrual cycle of 152 examples to compare treatment shortens, and shorten in average natural law is 7.2 days.After drug withdrawal, Continuous Observation 3 menstrual cycle, within wherein having 134 routine menstrual cycle to foreshorten to 35 days, menstruation is delayed and is cured.Through statistics, the effective percentage that this Chinese medicine composition delays a disease to treatment menstruation is 90.47%, and cure rate is 79.76%, proves that this Chinese medicine composition is delayed on a disease in treatment menstruation and achieves good curative effect.
Model case:
Female is 32 years old, married, 4 years after marriage unpregnancies always, time medical, react its menstrual period and obviously delay, maximum duration is dragged to 3 months and just comes, and less through amount during menstrual period, inquiry is learnt, it is i.e. menoxenia at an early age, mostly be menstrual period and delay, when menstruation comes, have obvious dysmenorrhea phenomenon, simultaneously the conscious cold of lower limb, appetite is poor, and build is become thin.Its two chi of pulse-taking moistens carefully, and right pass is sliding, left pass string, tentative diagnosis suffer from a deficiency of the kidney wood strongly fragrant caused by.
Take Chinese medicine composition provided by the present invention after 2 weeks, menstruation occurs, withdrawal, menstrual period, through measuring showed increased than before, 5 days persistent period, continue to take Chinese medicine composition provided by the present invention 2 weeks, according to menstruation last time menstruation in 31 days reproduction, thorough withdrawal.Observe half a year, menstruation monthly arrives on schedule, and menstruation was delayed and was able to thorough healing generally between 27-32 days the cycle.
Embodiment 3
A kind of Chinese medicine composition for the treatment of menstruation and delaying, it is characterized in that, this Chinese medicine composition adopts the material medicine of following weight proportion to combine: Herba Epimedii 15 parts, Cortex Moutan 35 parts, Radix Morindae Officinalis 9 parts, Rhizoma Cyperi 15 parts, Ramulus Cinnamomi 15 parts, Radix Achyranthis Bidentatae 35 parts, the Cortex Eucommiae 15 parts, Rhizoma Zingiberis 15 parts, 10 parts, Semen Persicae, Radix Dipsaci 35 parts, the Radix Polygoni Multiflori 10 parts, Herba Visci 35 parts, 10 parts, Radix Rehmanniae Preparata, 15 parts, Colla Corii Asini, Semen Cuscutae 15 parts, 30 parts, Poria, 3 parts, Radix Glycyrrhizae, Radix Salviae Miltiorrhizae 12 parts.
Embodiment 4
A kind of Chinese medicine composition for the treatment of menstruation and delaying, it is characterized in that, this Chinese medicine composition adopts the material medicine of following weight proportion to combine: Herba Epimedii 25 parts, Cortex Moutan 25 parts, Radix Morindae Officinalis 15 parts, Rhizoma Cyperi 9 parts, Ramulus Cinnamomi 25 parts, Radix Achyranthis Bidentatae 25 parts, the Cortex Eucommiae 25 parts, Rhizoma Zingiberis 9 parts, 20 parts, Semen Persicae, Radix Dipsaci 25 parts, the Radix Polygoni Multiflori 20 parts, Herba Visci 25 parts, 20 parts, Radix Rehmanniae Preparata, 9 parts, Colla Corii Asini, Semen Cuscutae 25 parts, 20 parts, Poria, 9 parts, Radix Glycyrrhizae, Radix Salviae Miltiorrhizae 6 parts.
Claims (2)
1. the Chinese medicine composition for the treatment of menstruation and delaying, it is characterized in that, this Chinese medicine composition adopts the material medicine of following weight proportion to combine: Herba Epimedii 15-25 part, Cortex Moutan 25-35 part, Radix Morindae Officinalis 9-15 part, Rhizoma Cyperi 9-15 part, Ramulus Cinnamomi 15-25 part, Radix Achyranthis Bidentatae 25-35 part, Cortex Eucommiae 15-25 part, Rhizoma Zingiberis 9-15 part, Semen Persicae 10-20 part, Radix Dipsaci 25-35 part, Radix Polygoni Multiflori 10-20 part, Herba Visci 25-35 part, Radix Rehmanniae Preparata 10-20 part, Colla Corii Asini 9-15 part, Semen Cuscutae 15-25 part, Poria 20-30 part, Radix Glycyrrhizae 3-9 part, Radix Salviae Miltiorrhizae 6-12 part.
2. a kind of Chinese medicine composition for the treatment of menstruation and delaying according to claim 1, it is characterized in that, optimum weight part of described material medicine is: Herba Epimedii 20 parts, Cortex Moutan 30 parts, Radix Morindae Officinalis 12 parts, Rhizoma Cyperi 12 parts, Ramulus Cinnamomi 20 parts, Radix Achyranthis Bidentatae 30 parts, the Cortex Eucommiae 20 parts, Rhizoma Zingiberis 12 parts, 15 parts, Semen Persicae, Radix Dipsaci 30 parts, the Radix Polygoni Multiflori 15 parts, Herba Visci 30 parts, 15 parts, Radix Rehmanniae Preparata, 12 parts, Colla Corii Asini, Semen Cuscutae 20 parts, 25 parts, Poria, 6 parts, Radix Glycyrrhizae, Radix Salviae Miltiorrhizae 9 parts.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104522241A (en) * | 2014-12-24 | 2015-04-22 | 邹立柱 | Heart-pleasuring and face-caring flores aurantii tea formula and production method thereof |
| CN105477619A (en) * | 2016-01-22 | 2016-04-13 | 王浩 | Traditional Chinese medicine composition for treating delayed menorrhea |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103341004A (en) * | 2013-06-27 | 2013-10-09 | 柳晖 | Chinese medicine composition for treating delayed menstrual cycle |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103341004A (en) * | 2013-06-27 | 2013-10-09 | 柳晖 | Chinese medicine composition for treating delayed menstrual cycle |
Non-Patent Citations (1)
| Title |
|---|
| 梁博: "月经延后的临床研究与治疗进展", 《黑龙江中医药》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104522241A (en) * | 2014-12-24 | 2015-04-22 | 邹立柱 | Heart-pleasuring and face-caring flores aurantii tea formula and production method thereof |
| CN104522241B (en) * | 2014-12-24 | 2017-05-31 | 邹立柱 | A kind of happy heart beauty treatment flores aurantii tea prescription and preparation method thereof |
| CN105477619A (en) * | 2016-01-22 | 2016-04-13 | 王浩 | Traditional Chinese medicine composition for treating delayed menorrhea |
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