CN1042078A

CN1042078A - The production technology of curing agent for appendicitis

Info

Publication number: CN1042078A
Application number: CN 89107812
Authority: CN
Inventors: 叶光华
Original assignee: Affiliated Hospital No1 Lanzhou Medical College
Current assignee: Affiliated Hospital No1 Lanzhou Medical College
Priority date: 1989-09-28
Filing date: 1989-09-28
Publication date: 1990-05-16

Abstract

Curing agent for appendicitis is to utilize Radix Zanthoxyli Planispini (stem) to typhlitic special efficacy, forms through the manufacturing of special producing technology, and its production technology mainly comprises: Fructus Zanthoxyli Plansipini is pulverized, and wet soaking filtered, and extracts, and pus contracts and step such as granulation.This is simple for process, the extraction efficiency height, and the Pianomide that makes is to simple property, early stage suppurative appendicitis, and particularly acute appendicitis has special efficacy, and short treating period, and is safe and reliable, has no side effect after the use.

Description

The production technology of curing agent for appendicitis

The present invention is a kind of medicinal principle of utilizing plant that relates to, the production technology of production for treating appendicitis-" curing agent for appendicitis ".

Acute appendicitis is the acute abdomen common disease, and sickness rate is high, and domestic report accounts for more than 50% of various abdomen diseases.In case the outbreak of vermiform appendix acute inflammation develops into suppurative perforation very soon, even gangrene, thereby concurrent limitation, even chronic peritonitis more, vermiform appendix inflammatory peripheral abscess, pus infections etc. under interbowel abscess, pelvic abscess, the diaphragm, cause severe infections, even toxic shock, patient's life jeopardized.The treatment of acute appendicitis branch operation treatment and Drug therapy are two kinds at present.Still based on operative treatment, operative treatment has many drawbacks in many areas, has promptly increased new misery and financial burden to patient, and easy again concurrent infection of incisional wound and intestinal adhesion in various degree influence patient's gastrointestinal function, develop adhesive ileus sometimes.And the western medicine curative effect is undesirable; In the method for China's peculiar traditional Chinese medical science combined treatment acute appendicitis, though obtained very great achievement, most of Chinese medicine compound that adopts also need add when having and use antibiotic.Not only flavour of a drug are many in the Chinese medicine, and dose is big, often are difficult to join complete, thereby certain side effect often arranged, and damage healthy energy makes appendicitis cure back patient's body constitution and weakens, disease such as easily catch a cold.

The objective of the invention is to invent a kind of for appendicitis curative effect height, short treating period, safety, without any side effects, production technology is simple, cost is low, takes " curing agent for appendicitis " of carrying convenience.

The production technology of curing agent for appendicitis is achieved in that Radix Zanthoxyli Planispini (stem) 1000 grams, cleans and pulverizes, and 100 mesh sieves are standby excessively to get 1/5th; All the other coarse powder are crossed liquid with the moistening of 50-80% ethanol; Extract three times in 40-70 ℃ of left and right sides warm macerating with 50-80% ethanol, add 5 times of amount 50-80% ethanol warm macerating for the first time and soaked 2-4 hour, each extracted second, third time respectively 2-3 hour with 3 times of amount 50-80% ethanol.Each extracting solution filters respectively, merges, and concentrating under reduced pressure becomes thick paste, and control proportion is 1.33-1.36 in the time of 15-30 ℃; Above-mentioned crude drug fine powder is added thick paste, and mixing adds appropriate amount of auxiliary materials, and as starch, Pulvis Talci etc., granulation, oven dry, granulate add the logical magnesium stearate of % again, and mixing, tabletting are promptly.

Compared with prior art, this curing agent for appendicitis has special efficacy to acute simple appendicitis and early stage suppurative appendicitis, and short treating period is safe and reliable, has no side effect after the use, and its production technology is easy, the yield height.

Claims

A kind of production technology for the treatment of the appendicitis medicament is characterized in that: Radix Zanthoxyli Planispini (stem) 1000 grams are pulverized, and 100 mesh sieves are standby excessively to get 1/5th; All the other coarse powder spend the night with the moistening of 50-80% ethanol, extract three times in 40-70 ℃ of warm macerating with 50-80% ethanol, adding for the first time 5 times of amount 50-80% ethanol warm macerating soaked 2-4 hour, each extracted second, third time respectively 2-3 hour with 3 times of amount 50-80% ethanol, each time extracting solution filters respectively, merges, and concentrating under reduced pressure becomes thick paste, mixing adds appropriate amount of auxiliary materials; Starch, Pulvis Talci, sugar and 1% magnesium stearate, mixing, the tabletting oven dry, granulate is promptly.