CN104189403A - Powder for preventing and treating viral necrosis - Google Patents
Powder for preventing and treating viral necrosis Download PDFInfo
- Publication number
- CN104189403A CN104189403A CN201410368920.9A CN201410368920A CN104189403A CN 104189403 A CN104189403 A CN 104189403A CN 201410368920 A CN201410368920 A CN 201410368920A CN 104189403 A CN104189403 A CN 104189403A
- Authority
- CN
- China
- Prior art keywords
- herba
- radix
- powder
- pvp
- sodium hypochlorite
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention provides powder for preventing and treating viral necrosis. The powder is prepared from the following components by weight: 100-150g of cortex dictamni, 100-150g of ramie root, 100-150g of buffalo horn, 60-80g of purslane herb, 60-80g of common andrographis herb, 60-80g of purple flower holly leaf, 60-80g of cape jasmine fruit, 60-80g of Japanese ampelopsis root, 60-80g of evodia lepta (Spreng.) merr., 60-80g of herba siegesbeckiae, 60-80g of Japanese thistle root, 60-80g of chrysanthemum, 40-60g of garlic, 40-60g of fossil fragments, 40-60g of manyleaf paris rhizome, 40-60g of bunge corydalis herb, 20-30g of liquorice, 1-3g of PVP-1 and 5-20g of sodium hypochlorite. The powder is simple in proportioning, is convenient to use, is specially used for nervous necrosis of groupers and has good prevention and treatment effects.
Description
technical field:
The present invention relates to technical field of pharmaceuticals, relate in particular to a kind of viral downright bad sick control powder.
background technology:
Sick fish performance anorexia, above bubbles through the water column, and performance helical form or rotation are moved about, or abdominal part floats on the water surface upward, is difficult to sink, the enlargement of sick fish belly portion, and some fish glue enlargement hyperemia, outward appearance is without other obvious pathological changes.The visible central nervous tissue brain cell of histological examination and retina cell vacuolation.This sick cause of disease belongs to Nodavirus section (Nodaviridae).This virus in 1989 find, nineteen ninety reported first.After this, in succession there are 3 15 kinds of marine fishs of order 8 section that this disease occurred all over the world.Can propagate by horizontal and vertical, prelarva and the juvenile fish of this sick major effect seed campaign, severe patient can reach 100 % death in one week, and alevin stage, sick fish anorexia, floated in the water surface, fish glue enlargement, without other outward appearance symptoms, mortality rate is high in addition.Spirally vertically moving about can appear in the sick fish of young stage, and mortality rate is low compared with alevin stage.The visible brain cell of histological examination and retina are because of necrocytosis and damage the ghost forming.Spherical virion in electron microscopic observation visible cell matter, diameter 25～30 nm, viral gene is made up of two sections of single stranded RNAs.The a large amount of cells of the visible central nervous system of pathologic finding, spinal cord and retinal tissue form cavity, occur nerve degraded.This disease Major Epidemic is on the prelarva and juvenile fish of the fishes such as stone Channa argus, the outside two of a team of horses, cabrilla, red fin east Bao, and mortality rate generally can reach 40%～100%, also has the adult fish of Partial Species can be infected.In recent years, on the green hata of Guangdong cultivation, the seed of purple with fishes such as hundred speckle fishes, also caused huge loss.Because this virus can be survived more than 60 days in sea water, so virus can be attached to ovum surface or dissociate and infection prelarva in water.This sick main disinfectant disinfection that uses of control at present.To this virus poison effectively disinfectant mainly contain the strong base solution of halogen, ethanol class, carbonic acid and pH value 12, as processed 10 minutes by sodium hypochlorite 50 mg/litre etc.Chinese medicine or its extract, for antiviral, have certain superiority, as low in drug residue, so it is necessary that Study of Traditional Chinese Medicine antiviral drugs is used for the treatment of viral nervous necrosis.
summary of the invention:
The object of the invention is to overcome the shortcoming existing in prior art, provide a kind of proportioning simple, easy to use, the aquaculture water virus killing of the special viral nervous necrosis for marine fish, the viral downright bad sick control powder that prevention effect is good.
To achieve these goals, the invention provides a kind of viral downright bad sick control powder, wherein, configure following each component according to unit of weight:
Cortex Dictamni, Radix Boehmeriae, the each 100-150g of Cornu Bubali, Herba Portulacae, Herba Andrographis, Ilex purpurea Hassk.[I.chinensis Sims, Fructus Gardeniae, Radix Ampelopsis, three bifurcation hardships, Herba Siegesbeckiae, Radix Cirsii Japonici, the each 60-80g of Flos Chrysanthemi, Bulbus Allii, Os Draconis, Rhizoma Paridis, the each 40-60g of Herba Violae, the each 20-30g of Radix Glycyrrhizae, PVP-1 is 1-3g, sodium hypochlorite 5-20g.
Or, configure following each component according to unit of weight:
Cortex Dictamni, Radix Boehmeriae, the each 100-120g of Cornu Bubali, Herba Portulacae, Herba Andrographis, Ilex purpurea Hassk.[I.chinensis Sims, Fructus Gardeniae, Radix Ampelopsis, three bifurcation hardships, Herba Siegesbeckiae, Radix Cirsii Japonici, the each 60-70g of Flos Chrysanthemi, Bulbus Allii, Os Draconis, Rhizoma Paridis, the each 40-50g of Herba Violae, the each 20-25g of Radix Glycyrrhizae, PVP-1 is 1-2g, sodium hypochlorite 10-20g.
Or, configure following each component according to unit of weight:
Cortex Dictamni, Radix Boehmeriae, the each 120-150g of Cornu Bubali, Herba Portulacae, Herba Andrographis, Ilex purpurea Hassk.[I.chinensis Sims, Fructus Gardeniae, Radix Ampelopsis, three bifurcation hardships, Herba Siegesbeckiae, Radix Cirsii Japonici, the each 70-80g of Flos Chrysanthemi, Bulbus Allii, Os Draconis, Rhizoma Paridis, the each 50-60g of Herba Violae, the each 25-30g of Radix Glycyrrhizae, PVP-1 is 2-3g, sodium hypochlorite 8-12g
The preparation method of viral downright bad sick control powder is as follows:
By the each crude drug component (Cortex Dictamni in above-mentioned Chinese medicine composition, Radix Boehmeriae, Cornu Bubali, Herba Portulacae, Herba Andrographis, Ilex purpurea Hassk.[I.chinensis Sims, Fructus Gardeniae, Radix Ampelopsis, three bifurcation hardships, Herba Siegesbeckiae, Radix Cirsii Japonici, Flos Chrysanthemi, Bulbus Allii, Os Draconis, Rhizoma Paridis, Herba Violae, Radix Glycyrrhizae) grind to form respectively fine powder, mix, obtain mixture, mixture is joined in the water of 6 ~ 8 times of amounts and decoct, each decoction 2 ~ 4 hours, decoct 3 times, decocted rear filtration at every turn, filtrate is mixed, carry out concentrating under reduced pressure and obtain extractum, by in the extractum alcoholic solution that to join with respect to the determining alcohol of 2 ~ 3 times of amounts of mixture quality be 90% ~ 95%, stir completely and dissolve, subsequently 4 DEG C of following hold over night of temperature, subsequent filtration, filtrate is carried out to concentrating under reduced pressure and remove ethanol, the mastic obtaining is pulverized, add PVP-1 and the sodium hypochlorite of powdery.Obtain medicated powder 200g left and right.
Use: the middle use that aborts of this medicine, medicated powder 200g is the sterilization consumption of 1 cubic metre of water.
Advantage of the present invention is, proportioning is simple, easy to use, specially for microsporidians, and the aquaculture water after sterilization, viral nervous necrosis sickness rate is low.Good to the prevention effect of viral nervous necrosis.
detailed description of the invention:
Experiment:
Material: Cortex Dictamni, Radix Boehmeriae, the each 100-150g of Cornu Bubali, Herba Portulacae, Herba Andrographis, Ilex purpurea Hassk.[I.chinensis Sims, Fructus Gardeniae, Radix Ampelopsis, three bifurcation hardships, Herba Siegesbeckiae, Radix Cirsii Japonici, the each 60-80g of Flos Chrysanthemi, Bulbus Allii, Os Draconis, Rhizoma Paridis, the each 40-60g of Herba Violae, the each 20-30g of Radix Glycyrrhizae, PVP-1 is the powder that 1-3g, sodium hypochlorite 5-20g make.
Treatment contrast, select at random the cabrilla of hemorrhage, be divided into 3 groups, every group 30, use merely sodium hypochlorite to sterilize as organizing one, use sea water after ozone filters for organizing two, the present invention is for organizing three, every group 30 are put in respectively in the sea water of 3 cubic metres, under equal conditions, infect with Nodavirus, within three days, observe afterwards.Find,
| Group | Death toll | Effective percentage % |
| Group one | 10 | 66.7 |
| Group two | 14 | 53.3 |
| Group three | 5 | 83.3 |
Antiviral experimental data:
To the interior resisting virus experiment of cabrilla
Get fish, divide 2 groups at random by body weight: viral infection matched group and intact animal's matched group, except Normal group, cabrilla is slightly anaesthetized, with the cabrilla intestinal arc virus infection of 15 LDSD, every 0.1ml, starts to put in a suitable place to breed respectively in above-mentioned group one, the water of group two, group three, for three days on end from infecting the previous day, after taking body weight, fix, dissect, get liver and calculate liver exponential quantity, calculate liver index suppression ratio
Heavy (the g)/body weight of liver index=liver (g) × 100
Liver index suppression ratio=(virus control group liver Mean value of index-experimental group liver Mean value of index)/virus control group liver Mean value of index × 100%
Liver index is larger, represents that liver pathological changes degree is serious, (because hemorrhagic disease causes each internal organs hemorrhage, select internal organs as index, also can select lung to carry out lung assessment of indices)
Hepatic tissue is fixed with 10% formaldehyde, ethanol series dehydration, dimethylbenzene is transparent, paraffin embedding, slice thickness 4-5 micron, HE dyeing, observes blood lipid with ordinary optical microscope and changes, select the antiviral group of broad spectrum antibiotic (PVP-1) as a comparison, can find out that successful of the present invention is better than broad spectrum antibiotic.
The impact (n=10) of liver's checking (virus is observed)
Can find, of the present invention to viral suppression ratio apparently higher than directly use PVP-1.
The experiment of toxicity to rat:
Acute oral (LD50) > 500mg/kg,
Acute percutaneous (LD 50) > 2000mg/kg,
Belong to low toxicity.
Object lesson 1
Zhang Jiayi plant, area 1500 square meters, approximately 5 meters of the depth of waters, put cabrilla 10,000 tails in a suitable place to breed, start morbidity dead fish successively in 8 months, and every day, the quantity of dead fish was multiplied, and a day dead cabrilla reaches tail more than 500 at most.Detect disease fish, the visible brain cell of histological examination and retina are because of necrocytosis and damage the ghost forming.Spherical virion in electron microscopic observation visible cell matter, diameter 25～30 nm, viral gene is made up of two sections of single stranded RNAs.The a large amount of cells of the visible central nervous system of pathologic finding, spinal cord and retinal tissue form cavity, occur nerve degraded.Be diagnosed as cabrilla nervous necrosis, use Cortex Dictamni of the present invention, Radix Boehmeriae, the each 150g of Cornu Bubali, Herba Portulacae, Herba Andrographis, Ilex purpurea Hassk.[I.chinensis Sims, Fructus Gardeniae, Radix Ampelopsis, three bifurcation hardships, Herba Siegesbeckiae, Radix Cirsii Japonici, the each 80g of Flos Chrysanthemi, Bulbus Allii, Os Draconis, Rhizoma Paridis, the each 60g of Herba Violae, the each 30g of Radix Glycyrrhizae, PVP-1 is 3g, sodium hypochlorite 20g.
By the each crude drug component (Cortex Dictamni in above-mentioned Chinese medicine composition, Radix Boehmeriae, Cornu Bubali, Herba Portulacae, Herba Andrographis, Ilex purpurea Hassk.[I.chinensis Sims, Fructus Gardeniae, Radix Ampelopsis, three bifurcation hardships, Herba Siegesbeckiae, Radix Cirsii Japonici, Flos Chrysanthemi, Bulbus Allii, Os Draconis, Rhizoma Paridis, Herba Violae, Radix Glycyrrhizae) grind to form respectively fine powder, mix, obtain mixture, mixture is joined in the water of 6 ~ 8 times of amounts and decoct, each decoction 2 ~ 4 hours, decoct 3 times, decocted rear filtration at every turn, filtrate is mixed, carry out concentrating under reduced pressure and obtain extractum, by in the extractum alcoholic solution that to join with respect to the determining alcohol of 2 ~ 3 times of amounts of mixture quality be 90% ~ 95%, stir completely and dissolve, subsequently 4 DEG C of following hold over night of temperature, subsequent filtration, filtrate is carried out to concentrating under reduced pressure and remove ethanol, the mastic obtaining is pulverized, add PVP-1 and the sodium hypochlorite of powdery.Obtain medicated powder 150-200g left and right.
Use: the middle use that aborts of this medicine, medicated powder 200g is the sterilization consumption of 1 cubic metre of water.
First, by sick fish isolation, dead fish is put into this medicine in sea water after pulling out, within every 2 days, throw in once, the dead quantity of the 1st day cabrilla after medication is 203 tails, the 2nd day dead quantity 164 tails of cabrilla, the 3rd day dead 68 tails, do not have fish Mortality on the 4th day.
Example 2
Li Jia plant 1200 square meters, put 8000 tails in a suitable place to breed, and summer and autumn find that Fish are dead successively, dead 456 of the highest day, and dissection discovery, visible brain cell and retina are because of the ghost of necrocytosis and breaking-up formation.Spherical virion in electron microscopic observation visible cell matter, diameter 25～30 nm, viral gene is made up of two sections of single stranded RNAs.The a large amount of cells of the visible central nervous system of pathologic finding, spinal cord and retinal tissue form cavity, occur nerve degraded.Be diagnosed as cabrilla nervous necrosis, use the present invention.
Cortex Dictamni, Radix Boehmeriae, the each 100g of Cornu Bubali, Herba Portulacae, Herba Andrographis, Ilex purpurea Hassk.[I.chinensis Sims, Fructus Gardeniae, Radix Ampelopsis, three bifurcation hardships, Herba Siegesbeckiae, Radix Cirsii Japonici, the each 60g of Flos Chrysanthemi, Bulbus Allii, Os Draconis, Rhizoma Paridis, the each 40g of Herba Violae, the each 20g of Radix Glycyrrhizae, PVP-1 is 2g, sodium hypochlorite 10g.
By the each crude drug component (Cortex Dictamni in above-mentioned Chinese medicine composition, Radix Boehmeriae, Cornu Bubali, Herba Portulacae, Herba Andrographis, Ilex purpurea Hassk.[I.chinensis Sims, Fructus Gardeniae, Radix Ampelopsis, three bifurcation hardships, Herba Siegesbeckiae, Radix Cirsii Japonici, Flos Chrysanthemi, Bulbus Allii, Os Draconis, Rhizoma Paridis, Herba Violae, Radix Glycyrrhizae) grind to form respectively fine powder, mix, obtain mixture, mixture is joined in the water of 6 ~ 8 times of amounts and decoct, each decoction 2 ~ 4 hours, decoct 3 times, decocted rear filtration at every turn, filtrate is mixed, carry out concentrating under reduced pressure and obtain extractum, by in the extractum alcoholic solution that to join with respect to the determining alcohol of 2 ~ 3 times of amounts of mixture quality be 90% ~ 95%, stir completely and dissolve, subsequently 4 DEG C of following hold over night of temperature, subsequent filtration, filtrate is carried out to concentrating under reduced pressure and remove ethanol, the mastic obtaining is pulverized, add PVP-1 and the sodium hypochlorite of powdery.Obtain medicated powder 150-200g left and right.
Use: the middle use that aborts of this medicine, medicated powder 200g is the sterilization consumption of 1 cubic metre of water.
First, by sick fish isolation, dead fish is put into this medicine in sea water after pulling out, within every 2 days, throw in once, the dead quantity of the 1st day cabrilla after medication is 322 tails, the 2nd day dead quantity 178 tails of cabrilla, the 3rd day dead 76 tails, do not have fish Mortality on the 4th day.
Example 3,
Wu Jia plant 900 square meters, put 6000 tails in a suitable place to breed, and summer and autumn find that Fish are dead successively, dead 392 of the highest day, and spherical virion in electron microscopic observation visible cell matter, diameter 25～30 nm, viral gene is made up of two sections of single stranded RNAs.The a large amount of cells of the visible central nervous system of pathologic finding, spinal cord and retinal tissue form cavity, occur nerve degraded.
Be diagnosed as cabrilla nervous necrosis, use the present invention.Cortex Dictamni, Radix Boehmeriae, the each 120g of Cornu Bubali, Herba Portulacae, Herba Andrographis, Ilex purpurea Hassk.[I.chinensis Sims, Fructus Gardeniae, Radix Ampelopsis, three bifurcation hardships, Herba Siegesbeckiae, Radix Cirsii Japonici, the each 70g of Flos Chrysanthemi, Bulbus Allii, Os Draconis, Rhizoma Paridis, the each 30g of Herba Violae, the each 25g of Radix Glycyrrhizae, PVP-1 is 1.5g, sodium hypochlorite 12g
By the each crude drug component (Cortex Dictamni in above-mentioned Chinese medicine composition, Radix Boehmeriae, Cornu Bubali, Herba Portulacae, Herba Andrographis, Ilex purpurea Hassk.[I.chinensis Sims, Fructus Gardeniae, Radix Ampelopsis, three bifurcation hardships, Herba Siegesbeckiae, Radix Cirsii Japonici, Flos Chrysanthemi, Bulbus Allii, Os Draconis, Rhizoma Paridis, Herba Violae, Radix Glycyrrhizae) grind to form respectively fine powder, mix, obtain mixture, mixture is joined in the water of 6 ~ 8 times of amounts and decoct, each decoction 2 ~ 4 hours, decoct 3 times, decocted rear filtration at every turn, filtrate is mixed, carry out concentrating under reduced pressure and obtain extractum, by in the extractum alcoholic solution that to join with respect to the determining alcohol of 2 ~ 3 times of amounts of mixture quality be 90% ~ 95%, stir completely and dissolve, subsequently 4 DEG C of following hold over night of temperature, subsequent filtration, filtrate is carried out to concentrating under reduced pressure and remove ethanol, the mastic obtaining is pulverized, add PVP-1 and the sodium hypochlorite of powdery.Obtain medicated powder 150-200g left and right.
Use: the middle use that aborts of this medicine, medicated powder 200g is the sterilization consumption of 1 cubic metre of water.
First, by sick fish isolation, dead fish is put into this medicine in sea water after pulling out, within every 2 days, throw in once, the dead quantity of the 1st day cabrilla after medication is 276 tails, the 2nd day dead quantity 124 tails of cabrilla, the 3rd day dead 62 tails, do not have fish Mortality on the 4th day.
To sum up, proportioning of the present invention is simple, easy to use, and specially for cabrilla nervous necrosis, prevention effect is good.
Claims (3)
1. a viral downright bad sick control powder, is characterized in that, configures following each component according to unit of weight:
Cortex Dictamni, Radix Boehmeriae, the each 100-150g of Cornu Bubali, Herba Portulacae, Herba Andrographis, Ilex purpurea Hassk.[I.chinensis Sims, Fructus Gardeniae, Radix Ampelopsis, three bifurcation hardships, Herba Siegesbeckiae, Radix Cirsii Japonici, the each 60-80g of Flos Chrysanthemi, Bulbus Allii, Os Draconis, Rhizoma Paridis, the each 40-60g of Herba Violae, the each 20-30g of Radix Glycyrrhizae, PVP-1 is 1-3g, sodium hypochlorite 5-20g.
2. viral downright bad sick control powder according to claim 1, is characterized in that, according to the following each component of unit of weight configuration:
Cortex Dictamni, Radix Boehmeriae, the each 100-120g of Cornu Bubali, Herba Portulacae, Herba Andrographis, Ilex purpurea Hassk.[I.chinensis Sims, Fructus Gardeniae, Radix Ampelopsis, three bifurcation hardships, Herba Siegesbeckiae, Radix Cirsii Japonici, the each 60-70g of Flos Chrysanthemi, Bulbus Allii, Os Draconis, Rhizoma Paridis, the each 40-50g of Herba Violae, the each 20-25g of Radix Glycyrrhizae, PVP-1 is 1-2g, sodium hypochlorite 10-20g.
3. viral downright bad sick control powder according to claim 1, is characterized in that, according to the following each component of unit of weight configuration:
Cortex Dictamni, Radix Boehmeriae, the each 120-150g of Cornu Bubali, Herba Portulacae, Herba Andrographis, Ilex purpurea Hassk.[I.chinensis Sims, Fructus Gardeniae, Radix Ampelopsis, three bifurcation hardships, Herba Siegesbeckiae, Radix Cirsii Japonici, the each 70-80g of Flos Chrysanthemi, Bulbus Allii, Os Draconis, Rhizoma Paridis, the each 50-60g of Herba Violae, the each 25-30g of Radix Glycyrrhizae, PVP-1 is 2-3g, sodium hypochlorite 8-12g.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410368920.9A CN104189403A (en) | 2014-07-30 | 2014-07-30 | Powder for preventing and treating viral necrosis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410368920.9A CN104189403A (en) | 2014-07-30 | 2014-07-30 | Powder for preventing and treating viral necrosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104189403A true CN104189403A (en) | 2014-12-10 |
Family
ID=52074875
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410368920.9A Withdrawn CN104189403A (en) | 2014-07-30 | 2014-07-30 | Powder for preventing and treating viral necrosis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104189403A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111329931A (en) * | 2020-04-30 | 2020-06-26 | 中国热带农业科学院热带生物技术研究所 | Traditional Chinese medicine additive for resisting SGIV and NNV and application |
| CN117205213A (en) * | 2023-11-07 | 2023-12-12 | 西北农林科技大学深圳研究院 | Application of dictamnine in preparation of fish viral nervous necrosis disease drugs |
-
2014
- 2014-07-30 CN CN201410368920.9A patent/CN104189403A/en not_active Withdrawn
Non-Patent Citations (1)
| Title |
|---|
| 战文斌: "《水产动物病害学》", 31 May 2004, 中国农业出版社 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111329931A (en) * | 2020-04-30 | 2020-06-26 | 中国热带农业科学院热带生物技术研究所 | Traditional Chinese medicine additive for resisting SGIV and NNV and application |
| CN117205213A (en) * | 2023-11-07 | 2023-12-12 | 西北农林科技大学深圳研究院 | Application of dictamnine in preparation of fish viral nervous necrosis disease drugs |
| CN117205213B (en) * | 2023-11-07 | 2024-03-29 | 西北农林科技大学深圳研究院 | Application of dictamnine in preparation of fish viral nervous necrosis disease drugs |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104256168B (en) | One boar functional feed and preparation method thereof | |
| CN106135318A (en) | A kind of Chinese medicine composition and its preparation method and application | |
| CN104187071A (en) | Fish feed for preventing and treating hemorrhagic diseases of grass carps | |
| CN103656505A (en) | Fish saprolegnia resisting traditional Chinese medicine extractive water aqua and preparation method thereof | |
| CN105031128A (en) | Traditional Chinese medicine composition for preventing or treating ectoparasite of aquatic culture animals and preparation method and application thereof | |
| CN104189403A (en) | Powder for preventing and treating viral necrosis | |
| CN104186970A (en) | Fish feed for preventing and treating hemorrhagic diseases of grass carps | |
| CN104189480A (en) | Traditional Chinese medicine powder for inhibiting viral nervous necrosis of sea fish | |
| CN102058722B (en) | Chinese herbal medicine fungicide special for holothurian culture | |
| CN104189802A (en) | Disinfection powder for preventing and treating nervous necrosis of fish | |
| CN103599260A (en) | Preparation method of heat-clearing, toxicity-removing, antibacterial and antiviral traditional Chinese medicine oral liquid for birds | |
| CN104189481A (en) | Medicine for preventing and treating viral nervous necrosis of fish | |
| CN115624578A (en) | Traditional Chinese medicine composition for inhibiting aeromonas hydrophila and application thereof | |
| CN104187072A (en) | Anti-virus fish feed for preventing and treating pancreatic necrosis of salmons and trout | |
| CN103349758A (en) | Liver protecting Chinese medicine preparation for aquiculture animals and preparation method thereof | |
| CN103006782A (en) | Ficus auriculata extract and application thereof in preparation of medicine used for treating osteoporosis | |
| CN108524746B (en) | Traditional Chinese medicine composition for preventing and treating poultry cold | |
| CN102895546B (en) | Chinese herbal medicine compound formula for preventing and treating apostichopus japonicus balantidiasis | |
| CN107080770B (en) | Compound traditional Chinese medicine for preventing and treating fish dactylogyrus disease and preparation and use methods thereof | |
| CN100399908C (en) | Prepn process of theasaponin sterilant for preventing and control rat plague | |
| CN104522794B (en) | Antrodia camphorata detoxifying beverage and preparation method thereof | |
| CN103816199B (en) | A kind of anti-duck virus hepatitis Chinese medical extract compound | |
| CN106578656A (en) | Traditional Chinese medicine feed additive and preparation method thereof | |
| CN116942710A (en) | Traditional Chinese medicine extract and application thereof in preparation of products for preventing, relieving or treating common fish virus diseases | |
| Ahamad et al. | Pathomorphology and Ethnoveterinary Herbal Intervention in an Outbreak of Newcastle Disease in Desi Chicken |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20141210 |
|
| WW01 | Invention patent application withdrawn after publication |