CN104187168A - Compound premix for preventing quail cold stress enteritis - Google Patents
Compound premix for preventing quail cold stress enteritis Download PDFInfo
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- CN104187168A CN104187168A CN201410459881.3A CN201410459881A CN104187168A CN 104187168 A CN104187168 A CN 104187168A CN 201410459881 A CN201410459881 A CN 201410459881A CN 104187168 A CN104187168 A CN 104187168A
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- premix
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Abstract
The invention relates to a compound premix for preventing quail cold stress enteritis, belongs to the field of feed additives and is used for solving the common problems that the quail cold stress enteritis occurs frequently and is seriously in the northeast area. The premix integrates the traditional Chinese medicines, the vitamins, the mineral substances and the effective components. The traditional Chinese medicines in the traditional Chinese medicine preparation of the premix are combined according to the principle of monarch, minister, assistance and guidance; through repeated tests and validations, the types and the optimal dosages of the traditional herbal medicines are creatively determined; and meanwhile, the premix plays roles of resisting cold stress and improving meat quality via oligomeric proanthocyanidins and saves the addition of vitamins C and E.
Description
Technical field
The invention provides a kind of compound premix that prevents quail cold stress enteritis, belong to field of feed additive technology.
Background technology
Quail is the special fowl that economic worth is very high, and China has become the first in the world and supported quail big country, have the good reputation of " animal ginseng ".By people, be considered as high-grade nourishing treasure, be also the important source material of herbal cuisine simultaneously.Quail not only edible nourishing is worth very high, its medical value is also very high, domestic quail aquaculture mainly concentrates on east and central China area, the Northeast because of region cold and low temperature time remaining long, environment temperature is starkly lower than the required minimum temperature of Feeding Quails, quail is because health is little, alimentary canal is not long, digestion power is not as good as other birds, responsive, strong to cold stress (Cold stress) reaction, the disease of digestive tracts such as quail poor growth, meat decline, diarrhoea malaria is had blood in stool are high, the death rate is high, and quail is higher to nutriment demand.At present, for quail premix compound special, almost do not have, in quail perfect compound feed, be all to make the conventional premix of birds, effect is not obvious, specific aim is poor, for the premix of anti-cold stress, have no in prior art and record, more the quail premix compound special about concentrating medicine, vitamin, mineral matter, functional component to be integrated not.
About glucosidase procyanidins, according to the difference of the degree of polymerization, OPC is divided into again glucosidase procyanidins (oligomericproathocyanidin, OPC) and high poly-OPC (polymeric proathocyanidin, PPC).The degree of polymerization is called high poly-OPC at more than 7 OPCs, and the OPC that the degree of polymerization is 2-7 is called glucosidase procyanidins.OPC can be removed free radical superfluous in body, improve the immunity of human body, can be used as the main active ingredient of anti-cancer, anti-sudden change, prevention and cure of cardiovascular disease medicine and as the natural of safety non-toxic etc., at field tools such as medicine, health care, food, daily-use chemical industries, have been widely used.Glucosidase procyanidins has stronger physiologically active.Glucosidase procyanidins has very strong oxidation resistance.The antioxidation activity of OPC is higher than VE and VC in vivo, and glucosidase procyanidins also has antibacterial, anti-inflammatory; Glucosidase procyanidins also can maintain skin elasticity, improves cutis laxa, coarse, wrinkle and regulation of skin function.In prior art, glucosidase procyanidins is also had to report for feed addictive, CN103271235 A discloses glucosidase procyanidins as the application that extends the feed addictive of quality guaranteed period of eggs, is wherein also applied to quail.CN1654463A discloses a kind of oligomeric proanthocyanidins and preparation method and application, and the oligomeric proanthocyanidins that wherein adds 400mg/kg in poultry feed does not affect egg quality, can also reduce the content of cholesterol in egg.Also report is not used it for the anti-cold stress of quail at present.
Summary of the invention
Object of the present invention: provide a kind of and have that cost is low, technique is simple, easy operating, without complex device, be applicable to the premix that concentrated medicine, vitamin, mineral matter, the functional component of the advantages such as large-scale breeding are integrated.
The technical problem that the present invention solves: solve that current the Northeast quail cold stress enteritis takes place frequently and serious common problem.The premix that provides concentrated medicine, vitamin, mineral matter, functional component to be integrated.
Technical scheme of the present invention:
On the basis of inventor's previous work, inventor provides a kind of compound premix that prevents quail cold stress enteritis, in weight portion: glucosidase procyanidins 10-20 part, dandelion 5-8 part, bark of eucommia 5-8 part, purslane 5-8 part, cordate houttuynia 5-8 part, Radix Astragali 5-8 part, plantain seed 5-8 part, mother chrysanthemum 5-8 part, vitamin A 0.5-0.8 part, vitamin D
30.01-0.3 part, Cobastab
10.05-0.07 part, Cobastab
20.5-1 part, Cobastab
60.1-0.6 part, Cobastab
120.08-0.1 part, folic acid 0.06-0.18 part, biotin 0.02-0.25 part, nicotinic acid 0.8-1.2 part; Kelp Powder 5-8 part, sodium selenite 2-3 part.
Described premix is pulverized rear mixing and be get final product by each raw material drying.
The application of described premix: meat quail, under the condition of 0 ~ 12 ± 1 ℃, is added this premix by weight 0.003%-0.01% in meat quail adequate diet.
The present invention also provides a kind of preparation method who prevents the compound premix of quail cold stress enteritis, this preparation method is mixed and made into the trickle powder of 600 object by dandelion 5-8 part, bark of eucommia 5-8 part, purslane 5-8 part, cordate houttuynia 5-8 part, Radix Astragali 5-8 part, plantain seed 5-8 part, mother chrysanthemum 5-8 part, both.Also can be by fine powder the warm water with 60 ℃, by weight, with the material-water ratio of 1:2, soak 2 hours, then with slow fire heating 30-50 minute, concentration is original volume 1/2nd, after filtration filtrate, after dusting, mix and get final product with other raw material of described weight portion.
Premix of the present invention can also be used other conventional method preparation.
Dandelion, has another name called dandelion, is the kind that health ministry is listed medicine-food two-purpose recently in.According to < < Compendium of Materia Medica > >, record, dandelion can heat-clearing poison, helping digestion is malicious, disappear that it is swollen to dislike.
The bark of eucommia: filling liver kidney, strengthening the bones and muscles.
Cordate houttuynia: taste is pungent; Cold nature; Return lung channel.Effect is clearing heat and detoxicating, inducing diuresis to reduce edema.Control pneumonia, lung abscess, hot dysentery, malaria, oedema, gonorrhoea, leukorrhea.
Chrysanthemum has dividing of mother chrysanthemum and family chrysanthemum, and wherein a family chrysanthemum clears liver and improve vision, the loose fire of mother chrysanthemum toxic removing, and sweetness and bitterness is slightly cold, clearing heat and detoxicating, and eyes strain, headache, hypertension etc. are all had to certain effectiveness.In < < Compendium of Materia Medica > >, the drug effect of chrysanthemum tea is also documented in detail: property is sweet, be slightly cold, there is the effect of loose wind-heat, flat liver improving eyesight.
Radix Astragali invigorating qi for consolidating superficies, holder sore myogenic.
Plantain seed reducing fever and causing diuresis.
Purslane has clearing heat and detoxicating, the effect such as stop blooding treating stranguria.Cure mainly acute, subacute dermatitis and enteritis, bacillary dysentery, treatment pyogenic infections from tumour or sore, damage by worms bite, eczema, appendicitis, hookworm disease, banded spore rash and functional uterine bleeding.1. antibacterial action: ethanol extract has the inhibitory action of height to Escherichia coli, proteus, shigella dysenteriae, typhoid fever, paratyphosum Bacterium. staphylococcus aureus, fungi are also had to inhibitory action in various degree as Austria Du big belly microspore tinea bacterium, tubercle bacillus.Pseudomonas aeruginosa is had to slight inhibitory action. experiment shows, when mouse peritoneal Escherichia Coli Injection infects, invalid with residue water decoction after alcohol extract or alcohol extracting.
Beneficial effect of the present invention:
(1) premix that medicine, vitamin, mineral matter, functional component are integrated is concentrated in this premix.
(2) Chinese medicine in premix Chinese prescription of the present invention is by the principle compatibility of " monarch ", through repetition test and final kind and the optimum amount of having determined Chinese herbal medicine of innovating of checking, under the existence of vitamin and mineral matter, greatly reduced the use of Chinese medicine material kind, although reduce, but still have synergistic function between various traditional Chinese medicine ingredients, its technique effect is also very good, treatment quail cold stress enteritis is had to splendid and unexpected technique effect.It is monarch that the clearing heat and detoxicating dandelion of the cool blood of detoxicating, clearing heat and detoxicating antibacterial purslane are take in the present invention, minister is clearing heat and detoxicating to have, the hot dysentery of inducing diuresis to reduce edema, the cordate houttuynia of malaria effect, assistant is with invigorating qi for consolidating superficies, the Radix Astragali of holder sore myogenic and the plantain seed of reducing fever and causing diuresis, to have the loose fire of toxic removing, the chrysanthemum that sweetness and bitterness is slightly cold is for making coordinating the drug actions of a prescription.
(3) bringing into play the anti-cold stress of glucosidase procyanidins simultaneously, improve these two kinds of functions of meat, is trial and the breakthrough of field of fodder; Inventor finds unexpectedly, uses glucosidase procyanidins can omit the interpolation of using vitamin C and vitamin E, still can obtain same technique effect, has reduced cost.
(4) mineral matter is only used the effect that Kelp Powder, sodium selenite just can reach.Each constituent content cooperatively interacts, Synergistic, and the obvious grow of anti-cold stress ability of meat quail, intestines problem significantly reduces, and meat tenderizes and is flexible.This feed addictive can meet the nutritional need of poultry in best immune state, improves the ability of supporting cold stress of poultry, especially quail.The present invention can avoid the use of the additives such as hormone, antibiotic, is of value to the health of animals and humans, increases edible safety.
the specific embodiment
Embodiment 1: a kind of compound premix special that prevents quail cold stress enteritis, it is characterized in that this compound premix made by following raw material, in weight portion: 10 parts of glucosidase procyanidins, 5 parts of dandelions, 5 parts of the barks of eucommia, 5 parts of purslanes, 5 parts of cordate houttuynias, 5 parts of the Radixs Astragali, 5 parts of plantain seeds, 5 parts of mother chrysanthemums, 0.5 part of vitamin A, vitamin D
30.01 part, Cobastab
10.05 part, Cobastab
20.5, Cobastab
60.1 part, Cobastab
120.08 part, 0.06 part, folic acid, 0.02 part of biotin, 0.8 part, nicotinic acid; 5 parts of Kelp Powders, 2 parts of sodium selenites.
Embodiment 2: a kind of compound premix special that prevents quail cold stress enteritis, it is characterized in that this compound premix made by following raw material, in weight portion: 20 parts of glucosidase procyanidins, 8 parts of dandelions, 8 parts of the barks of eucommia, 8 parts of purslanes, 8 parts of cordate houttuynias, 8 parts of the Radixs Astragali, 8 parts of plantain seeds, 8 parts of mother chrysanthemums, 0.8 part of vitamin A, vitamin D
30.3 part, Cobastab
10.07 part, Cobastab
21 part, Cobastab
60.6 part, Cobastab
120.1 part, 0.18 part, folic acid, 0.25 part of biotin, 1.2 parts, nicotinic acid; 8 parts of Kelp Powders, 3 parts of sodium selenites.
3 one kinds of compound premix specials that prevent quail cold stress enteritis of embodiment, it is characterized in that this compound premix made by following raw material, in weight portion: 15 parts of glucosidase procyanidins, 7 parts of dandelions, 6 parts of the barks of eucommia, 6 parts of purslanes, 6 parts of cordate houttuynias, 6 parts of the Radixs Astragali, 6 parts of plantain seeds, 6 parts of mother chrysanthemums, 0.6 part of vitamin A, vitamin D
30.08 part, Cobastab
10.06 part, Cobastab
20.6 part, Cobastab
60.5 part, Cobastab
120.09 part, 0.08 part, folic acid, 0.08 part of biotin, 1.0 parts, nicotinic acid; 6 parts of Kelp Powders, 2.5 parts of sodium selenites.
Contrast test
Materials and methods
Laboratory sample: Chinese medicine composition of the present invention and feed, by formula of the present invention and method preparation.
Animal used as test
Experimental animal is the meat quail of the Sha Weimate of 1 age in days, totally 220, during raising to 7 age in days, be divided at random 2 groups, every group 120, 1 group is that Normal group (feed routinely by quail perfect compound feed, in feed, contain conventional quail or fowl vitamin, mineral substance premix, by 0.01%, add), all the other 1 group (the 2nd group) feeds, and the feed that contains Chinese medicine composition (feed routinely by quail perfect compound feed, in feed, premix replaces with premix of the present invention), feed 20 days, other condition such as feeding and management method is all consistent, in whole process of the test, each organizes the equal free choice feeding of young quail and drinking-water.
To carrying out the stimulation of quail cold stress: get above-mentioned two groups of equal healthy quails, get respectively 100 for every group, carry out cold stress processing respectively at 12 ± 1 ℃, stress the time 10d respectively.In whole process of the test, each organizes the equal free choice feeding of young quail and drinking-water, searches for food as the conventional daily ration of quail.The clinical manifestation of keeper's observed and recorded.In experimentation, choose and occur that the quail (symptom of digestive tract such as all appearance are suffered from diarrhoea, had blood in stool, dysentery, lassitude be all considered as disease quail) of intestinal inflammatory symptom counts.
Results and analysis
Table 2 clinical test results
| Group | Morbidity number | Healthy number | The incidence of disease | Self-healing |
| The 1st group | 40 | 60 | 40% | 6 |
| The 2nd group | 5 | 95 | 5% | 4 |
Table 2 analysis result shows, illustrates that feed of the present invention all has obvious prevention effect to the quail all kinds intestinal inflammatory being caused by cold stress.
Claims (5)
1. a compound premix special that prevents quail cold stress enteritis, it is characterized in that this compound premix made by following raw material, in weight portion: glucosidase procyanidins 10-20 part, dandelion 5-8 part, bark of eucommia 5-8 part, purslane 5-8 part, cordate houttuynia 5-8 part, Radix Astragali 5-8 part, plantain seed 5-8 part, mother chrysanthemum 5-8 part, vitamin A 0.5-0.8 part, vitamin D
30.01-0.3 part, Cobastab
10.05-0.07 part, Cobastab
20.5-1 part, Cobastab
60.1-0.6 part, Cobastab
120.08-0.1 part, folic acid 0.06-0.18 part, biotin 0.02-0.25 part, nicotinic acid 0.8-1.2 part; Kelp Powder 5-8 part, sodium selenite 2-3 part.
2. premix as claimed in claim 1, is characterized in that, each raw material drying is pulverized rear mixing and be get final product.
3. the application of premix as claimed in claim 1 or 2: meat quail under the condition of 12 ± 1 ℃, in meat quail adequate diet by weight the preferred 0.01%-0.03% of 0.003%-0.05%() add this premix.
4. a kind of preparation method who prevents the compound premix of quail cold stress enteritis described in claim 1, this preparation method is mixed and made into the trickle powder of 600 object by dandelion 5-8 part, bark of eucommia 5-8 part, purslane 5-8 part, cordate houttuynia 5-8 part, Radix Astragali 5-8 part, plantain seed 5-8 part, mother chrysanthemum 5-8 part, warm water with 60 ℃, by weight, material-water ratio with 1:2 soaks 2 hours, again with slow fire heating 30-50 minute, concentration is 1/2nd of original volume, filter to get filtrate, after dusting, mix and get final product with other raw material of described weight powder.
5. the application of the premix that method obtains as claimed in claim 4: meat quail, under the condition of 0 ~ 12 ± 1 ℃ or 12 ± 1 ℃, is added this premix by weight 0.003%-0.05% in meat quail adequate diet.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410459881.3A CN104187168B (en) | 2014-09-11 | 2014-09-11 | A kind of compound premix preventing quail cold stress enteritis |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410459881.3A CN104187168B (en) | 2014-09-11 | 2014-09-11 | A kind of compound premix preventing quail cold stress enteritis |
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| CN104187168A true CN104187168A (en) | 2014-12-10 |
| CN104187168B CN104187168B (en) | 2016-04-06 |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1126551A (en) * | 1995-07-11 | 1996-07-17 | 张映春 | Converting agent for multivitamin chicken feed |
| WO2004091307A2 (en) * | 2003-04-08 | 2004-10-28 | Advanced Bionutriton Corporation | Feed additives against diseasse infection in terrestrial and aquatic animals |
| CN1654463A (en) * | 2004-02-13 | 2005-08-17 | 杭州利欣生物科技有限公司 | Procyanidins oligomer and its preparing method and use |
| CN101485399A (en) * | 2009-02-25 | 2009-07-22 | 山东中基牧业发展有限公司 | Composite premix feed for egg-laying quail and processing technique thereof |
| CN103271235A (en) * | 2013-04-02 | 2013-09-04 | 中国农业科学院北京畜牧兽医研究所 | Application of oligomeric procyanidine as feed additive for prolonging shelf lives of eggs |
-
2014
- 2014-09-11 CN CN201410459881.3A patent/CN104187168B/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1126551A (en) * | 1995-07-11 | 1996-07-17 | 张映春 | Converting agent for multivitamin chicken feed |
| WO2004091307A2 (en) * | 2003-04-08 | 2004-10-28 | Advanced Bionutriton Corporation | Feed additives against diseasse infection in terrestrial and aquatic animals |
| CN1654463A (en) * | 2004-02-13 | 2005-08-17 | 杭州利欣生物科技有限公司 | Procyanidins oligomer and its preparing method and use |
| CN101485399A (en) * | 2009-02-25 | 2009-07-22 | 山东中基牧业发展有限公司 | Composite premix feed for egg-laying quail and processing technique thereof |
| CN103271235A (en) * | 2013-04-02 | 2013-09-04 | 中国农业科学院北京畜牧兽医研究所 | Application of oligomeric procyanidine as feed additive for prolonging shelf lives of eggs |
Non-Patent Citations (1)
| Title |
|---|
| 王瑞琴，等: ""维生素抗冷应激的作用机制"", 《东北农业大学学报》, vol. 40, no. 7, 31 July 2009 (2009-07-31), pages 140 - 144 * |
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