CN104127479A - Medicament for treating neonatal tetanus - Google Patents
Medicament for treating neonatal tetanus Download PDFInfo
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- CN104127479A CN104127479A CN201410415439.0A CN201410415439A CN104127479A CN 104127479 A CN104127479 A CN 104127479A CN 201410415439 A CN201410415439 A CN 201410415439A CN 104127479 A CN104127479 A CN 104127479A
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Abstract
The invention relates to a medicament for treating neonatal tetanus. The medicament is prepared from the following Chinese herbal medicines as active ingredients in parts by weight: 5-12 parts of bombyx batryticatus, 2-5 parts of cinnabaris, 2-6 parts of realgar, 6-15 parts of semen crotonis pulveratum, 5-12 parts of scorpion, 8-15 parts of radix glycyrrhizae. The medicament achieves the effects of dispelling wind and coursing the exterior, detoxifying and relieving spasm, clearing away the heart fire and relieving convulsion, and is good in curative effect, free from toxic and side effects, and the total effective rate of the treatment can achieve up to 97.9%.
Description
Technical field
The present invention relates to biomedicine field, be specifically related to a kind of medicine for the treatment of tetanus neonatorum.
Background technology
Tetanus neonatorum is one of commonly encountered diseases after neonate unclean delivering a child of when birth, be by clostridium tetani by umbilical part, occasionally can be invaded and the acute infectious diseases that cause by the outer injury of neonate, tetanus neonatorum is the serious hygienic issues of developing country.It is conscious that the symptom of infant performance mostly is infant, early stage how heating, later fervescence can because of whole-body muscle repeatedly tetanic spasm cause, also can be because of due to the secondary infection such as pneumonia, through the person that can spend spasm period of processing in time, its outbreak reduces gradually, alleviate, after several weeks, fully recover, otherwise because of all the more more frequently, anoxia asphyxia or secondary infection and death.
Treatment tetanus neonatorum at present, except umbilical cord processing will tightly be sterilized, adopt diazepam and phenobarbital to replace the quiet method pushing away more, but stimulate blood vessel while stabilizing quiet pushing away, spasmolytic again after causing neonate again to occur extracting out, and the stable half-life is short, pushing away number of times therefore quiet should be many, and amount is difficult to be controlled, in addition because neonate is weaker, carry out intramuscular injection and penetrate, neonatal skin is caused damage, increased neonatal misery.
Summary of the invention
For above-mentioned situation, the object of this invention is to provide a kind of medicine for the treatment of tetanus neonatorum, taking convenience, therapeutic effect is good, has no side effect.
Technical scheme of the present invention is as follows, and a kind of medicine for the treatment of tetanus neonatorum is to be the medicament that crude drug prepares by the Chinese medicine of following parts by weight:
Bombyx Batryticatus 5-12 Cinnabaris 2-5 Realgar 2-6
Semen Crotonis Pulveratum 6-15 Scorpio 5-12 Radix Glycyrrhizae 8-15.
Preferably, described medicine is to be the medicament that crude drug prepares by the Chinese medicine of following parts by weight:
Bombyx Batryticatus 10 Cinnabaris 2 Realgars 3
Semen Crotonis Pulveratum 10 Scorpio 10 Radix Glycyrrhizaes 10.
The medicine of above-mentioned treatment tetanus neonatorum, its preparation method is as follows:
It is 100-150 object fine powder mix homogeneously that described crude drug is cleaned to dried and crushed, is distributed into bag sealing, and every bag of 1g, obtains medicine of the present invention.
Chinese medicine thinks that tetanus neonatorum is by after wound, or has infection focus, loses in medical treatment, and healthy energy is impaired, and the ailment said due to cold or exposure intrusion of taking advantage of a loophole, in table people, due to priming liver-wind.Bombyx Batryticatus endogenous wind stopping relieving convulsion in prescription of the present invention, wind-expelling pain-stopping, dissipating phlegm and resolving masses; Cinnabaris clears away heart-fire relieving convulsion, calms the nerves, and improving eyesight, removing toxic substances; Realgar removing toxic substances parasite killing, removing dampness and eliminating phlegm, preventing the attack (or recurrence) of malaria; Semen Crotonis Pulveratum drastic purgation is cold long-pending, the detumescent of relieving oedema or abdominal distension through diuresis or purgation, eliminating phlegm sore-throat relieving; Scorpio endogenous wind stopping spasmolytic, removing obstruction in the collateral to relieve pain, dispersing pathogen accumulation; Radix Glycyrrhizae invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription, Bombyx Batryticatus and Cinnabaris share the relieving the exterior syndrome that dispels the wind, and convulsion is determined in removing toxic substances; Realgar, Semen Crotonis Pulveratum, Scorpio are share relieving convulsion, the detumescent pain relieving that clears away heart-fire.All medicines share the relieving the exterior syndrome that can dispel the wind, and convulsion is determined in removing toxic substances, clears away heart-fire relieving convulsion.
Use clinically medicine of the present invention to carry out safety and observation of curative effect to treatment tetanus neonatorum:
Patient's data:
Tetanus neonatorum 48 examples, male 31 examples, female's 17 examples; Birth sequela 4d 3 examples, 6d 8 examples, 7d 11 examples, 8d 9 examples, 9d 5 examples, 11d 4 examples, 12d 6 examples, 14d 2 examples, all have the unclean history of delivering a child, and there is refusing breast in morbidity the same day, after within the 2nd day, occurring stimulating, occurs risus sardonicus, gnathospasma.
Diagnostic criteria
1, the process of delivering a child while having childbirth and umbilical part have the local non-sterile of wound to process history after processing the not tight history of sterilization or neonate birth;
2, clinical manifestation
4～6d after birth, minority is early fallen ill to 14d late above to 2d.
Early stage gnathospasma, suction breast difficulty, then facial spasm is risus sardonicus.Limb muscle paroxysmal tonic spasm, rectus abdominis m. spasm is tetanic as tabular, and stiffness of the neck is opisthotonus.Respiratory muscle, laryngospasm can cause suffocate, respiratory failure, heart failure.
3, umbilical part or wound secretions do anaerobic culture, and some cases (30% left and right) can obtain the clostridium tetani positive.
Therapeutic Method, the medicament of the oral embodiment of the present invention 1 of infant, each 1g, every day 1 time, takes with milk or gingerade.
Curative effect determinate standard:
Recovery from illness: whole body and local symptom, sign disappear, without complication;
Effective: whole body and local symptom, sign disappear substantially;
Invalid: whole body and local symptom, sign are without improving or increasing the weight of.
Therapeutic outcome
48 routine infants, 32 examples of fully recovering, cure rate 66.7%; Effective 15, obvious effective rate 31.2%; Total effective rate 97.9%; Invalid 1 example, inefficiency 2.1%.
Detailed description of the invention
Embodiment 1
Get Bombyx Batryticatus 10kg, Cinnabaris 2 kg, Realgar 3 kg, Semen Crotonis Pulveratum 10 kg, Scorpio 10 kg, Radix Glycyrrhizae 10 kg;
It is 120 object fine powder mix homogeneously that above-mentioned raw materials medicine is cleaned to dried and crushed, is distributed into bag sealing, and every bag of 1g, obtains medicine of the present invention.
Embodiment 2
Get Bombyx Batryticatus 8kg, Cinnabaris 3kg, Realgar 6kg, Semen Crotonis Pulveratum 12kg, Scorpio 6kg, Radix Glycyrrhizae 13 kg;
It is 150 object fine powder mix homogeneously that above-mentioned raw materials medicine is cleaned to dried and crushed, is distributed into bag sealing, and every bag of 1g, obtains medicine of the present invention.
Claims (2)
1. treat a medicine for tetanus neonatorum, it is characterized in that by the Chinese medicine of following parts by weight being that crude drug prepares:
Bombyx Batryticatus 5-12 Cinnabaris 2-5 Realgar 2-6
Semen Crotonis Pulveratum 6-15 Scorpio 5-12 Radix Glycyrrhizae 8-15.
2. the medicine for the treatment of tetanus neonatorum according to claim 1, it is characterized in that by the Chinese medicine of following parts by weight being that crude drug prepares:
Bombyx Batryticatus 10 Cinnabaris 2 Realgars 3
Semen Crotonis Pulveratum 10 Scorpio 10 Radix Glycyrrhizaes 10.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410415439.0A CN104127479A (en) | 2014-08-22 | 2014-08-22 | Medicament for treating neonatal tetanus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410415439.0A CN104127479A (en) | 2014-08-22 | 2014-08-22 | Medicament for treating neonatal tetanus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104127479A true CN104127479A (en) | 2014-11-05 |
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ID=51800501
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410415439.0A Pending CN104127479A (en) | 2014-08-22 | 2014-08-22 | Medicament for treating neonatal tetanus |
Country Status (1)
| Country | Link |
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| CN (1) | CN104127479A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101991781A (en) * | 2009-08-26 | 2011-03-30 | 栗素琴 | Traditional Chinese medicine preparation for treating tetanus |
| CN102240368A (en) * | 2011-08-05 | 2011-11-16 | 胡海舰 | Chinese medicinal preparation for treating tetanus |
-
2014
- 2014-08-22 CN CN201410415439.0A patent/CN104127479A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101991781A (en) * | 2009-08-26 | 2011-03-30 | 栗素琴 | Traditional Chinese medicine preparation for treating tetanus |
| CN102240368A (en) * | 2011-08-05 | 2011-11-16 | 胡海舰 | Chinese medicinal preparation for treating tetanus |
Non-Patent Citations (1)
| Title |
|---|
| 中国药材公司编著: "《中国民间单验方》", 31 October 1994 * |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20141105 |
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| RJ01 | Rejection of invention patent application after publication |