CN104116076A - Angelica keiskei capsule and preparing method thereof - Google Patents
Angelica keiskei capsule and preparing method thereof Download PDFInfo
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- CN104116076A CN104116076A CN201410330284.0A CN201410330284A CN104116076A CN 104116076 A CN104116076 A CN 104116076A CN 201410330284 A CN201410330284 A CN 201410330284A CN 104116076 A CN104116076 A CN 104116076A
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- traditional chinese
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- angelica keiskei
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- 238000000034 method Methods 0.000 title abstract description 3
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/30—Encapsulation of particles, e.g. foodstuff additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Neurosurgery (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
An angelica keiskei capsule and a preparing method thereof are provided. The traditional Chinese medicine capsule is prepared by subjecting traditional Chinese medicine components including 38-40% of angelica keiskei, 20-22% of baikal skullcap root, 18-20% of root of kudzu vine and 20-22% of ginkgo leaf to smashing, extraction and mixing. The traditional Chinese medicine capsule is prepared by smashing, extracting, mixing, preparing the capsule, sterilizing and packaging. The capsule is capable of effectively preventing generation of cholesterol, increasing the flow of blood vessel of brain, reducing resistance of blood vessel of brain, improving circulatory functions of the blood vessel of brain, protecting brain cells from being damaged by ischemia, expanding coronary artery, preventing stenocardia and myocardial infarction, inhibiting platelet aggregation, preventing formation of thrombosis, clearing harmful oxyradicals, boosting immunity, and improving and promoting health-care functions of blood circulation, and is beneficial to patients with senile dementia, hypertension, and the like.
Description
Technical field
The technical field of the present invention and health food, especially refers to a kind of Angelica Keiskei capsule and preparation method thereof.
Background technology
Angelica Keiskei has another name called tomorrow leaf, eight zhang of grass, it contains the very abundant medicinal ingredients such as his spit of fland and prevents aging necessary various vitamin, mineral matter and trace element, there is anticancer, to prevent cell senescence, conditioning chronic disease effect, the various diseases such as hepatitis, hypertension, diabetes, constipation are all had to significant curative effect, also there is the blood circulation of improvement simultaneously, strengthen cardiovascular function, antitumor, strengthen immunity, delay senility and the effect such as anti-oxidant, hypoglycemic, hypotensive.
Nowadays use modern genetic engineering technology, can from Angelica Keiskei, extract natural flavone element medicinal ingredient, and the root of large-flowered skullcap, the root of kudzu vine, ginkgo leaf all contain abundant flavonol, steady blood pressure, blood sugar are had to facilitation.And on market, utilize the products such as Angelica Keiskei production health products to be in stock, but the research that utilizes Angelica Keiskei to make oral capsule has no report, and because the Angelica Keiskei root of large-flowered skullcap, the root of kudzu vine, ginkgo leaf have the careless fishy smell that makes us unhappy, common people are difficult to accept.For this reason, eliminating above-mentioned deficiency, make oral capsule, make it both keep the medicinal and nutritional labeling of Angelica Keiskei, eliminate again unhappy smell, is a good method of killing two birds with one stone.
Summary of the invention
A kind of Angelica Keiskei capsule of the present invention and preparation method thereof, adopting Angelica Keiskei to be aided with the root of large-flowered skullcap, the root of kudzu vine, ginkgo leaf 3 taste Chinese medicines is raw material, through pulverizing, extraction, mixing, capsule processed, sterilization packaging, prepare Chinese medicinal capsule, can realize the object of improving blood circulation and promoting health care.
To achieve these goals, technical solution of the present invention is: the traditional Chinese medicinal components of a kind of Angelica Keiskei capsule and preparation method thereof: Angelica Keiskei 38%~40%, the root of large-flowered skullcap 20%~22%, the root of kudzu vine 18%~20%, ginkgo leaf 20%~22%.
Preparation process is as follows:
(1) get the raw materials ready: traditional Chinese medicinal components is carried out respectively to removal of impurities, dry, pulverize, cross 60 mesh sieves, extracting screen underflow, in obtaining
Medicinal powder;
(2) extraction: adopt supercritical extracting equipment device, traditional Chinese medicine powder is put into respectively to supercritical CO
2in the extraction kettle of extraction equipment, add supercritical CO
2for extractant, 30 ℃~50 ℃ of extraction temperature, extracting pressure 15Mpa~30Mpa, extraction time is 4h~6h, then adopts intensification, step-down to carry out separation, collects product in separating still and must extract powder;
(3) mix: the extraction powder of each traditional Chinese medicinal components is packed in the efficient asymmetric mixer of V-type in proportion, turn/min of speed of agitator 12, incorporation time 40min~60 min, obtains mixed powder;
(4) capsule processed: mixed powder is added to make every quality in capsule loading machine be 0.5g capsule;
(5) sterilization packaging: capsule is inserted after the lower 20min of irradiation of ultraviolet ray to packing in time.
The effect of traditional Chinese medicinal components of the present invention and effect:
Angelica Keiskei herb all can hyoscine, and the composition that contains rutin sophorin, choline, pantothenic acid, and it can strengthen, and body immunity, antibacterial, anti-blood are fastened, for cancer, antiulcer, prevent the effect of cell senescence, conditioning chronic disease.
The root of the root of large-flowered skullcap is used as medicine, and bitter, cold in nature has heat-clearing and damp-drying drug, purging intense heat and detonicating, hemostasis, the effect such as antiabortive.Cure mainly the diseases such as warm heat disease, the infection of the upper respiratory tract, cough with lung heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, hot eyes, fetal irritability, hypertension, the swollen furuncle sore of carbuncle.The clinical antibiotic property of the root of large-flowered skullcap is better than the coptis, and does not develop immunity to drugs.
The main isoflavone-containing compounds of the root of kudzu vine, main component has Dai, daidzin, Puerarin.Dai belongs to aglycon, and daidzin and Puerarin all belong to glycosides.Daidzin and Puerarin all belong to glycosides, and the aglycon of daidzin and Puerarin is identical, are all Dais.Although daidzin and Puerarin are all the glycosides of Dai, formed glycosides is different.Daidzin is an oxygen glycosides, and Puerarin is a carbon glycosides.
Flavones structure type contained in ginkgo leaf is many, comprises flavones, flavonols and glycoside thereof, also comprises catechin and bisflavones.Wherein most typical is to contain bis-flavonoid, and the flavone compound in ginkgo leaf has expansion coronary vasodilator and increases the effect of cerebral blood flow (CBF).
The present invention is through clinical, early, middle and lately respectively takes 2, can effectively stop generation cholesterol; increase cerebrovascular flow, reduce cerebral vascular resistance, improve cerebrovascular circulatory function; protection brain cell, avoids ischemic damage, coronary artery dilator; prevent angina pectoris and miocardial infarction; suppress platelet aggregation, prevent thrombosis, remove harmful oxyradical; the health-care effect that can improve immunity and improvement and stimulate circulation is all very useful to patients such as senile dementia, hypertension.
The specific embodiment
Embodiment 1
(1) traditional Chinese medicinal components: Angelica Keiskei 38%%, the root of large-flowered skullcap 22%, the root of kudzu vine 18%, ginkgo leaf 22%.
(2) preparation process is as follows:
1. get the raw materials ready: traditional Chinese medicinal components is carried out respectively to removal of impurities, dry, pulverize, cross 60 mesh sieves, extracting screen underflow, in obtaining
Medicinal powder;
2. extraction: adopt supercritical extracting equipment device, traditional Chinese medicine powder is put into respectively to supercritical CO
2in the extraction kettle of extraction equipment, add supercritical CO
2for extractant, 30 ℃ of extraction temperature, extracting pressure 30Mpa, extraction time is 6h, then adopts intensification, step-down to carry out separation, collects product in separating still and must extract powder;
3. mix: the extraction powder of each traditional Chinese medicinal components is packed in the efficient asymmetric mixer of V-type in proportion, turn/min of speed of agitator 12, incorporation time 40min, obtains mixed powder;
4. capsule processed: mixed powder is added to make every quality in capsule loading machine be 0.5g capsule;
5. sterilization packaging: capsule is inserted after the lower 20min of irradiation of ultraviolet ray to packing in time.
Embodiment 2
(1) traditional Chinese medicinal components: Angelica Keiskei 39%, the root of large-flowered skullcap 21%, the root of kudzu vine 19%, ginkgo leaf 21%.
(2) preparation process is as follows:
1. get the raw materials ready: traditional Chinese medicinal components is carried out respectively to removal of impurities, dry, pulverize, cross 60 mesh sieves, extracting screen underflow, in obtaining
Medicinal powder;
2. extraction: adopt supercritical extracting equipment device, traditional Chinese medicine powder is put into respectively to supercritical CO
2in the extraction kettle of extraction equipment, add supercritical CO
2for extractant, 40 ℃ of extraction temperature, extracting pressure 25Mpa, extraction time is 5h, then adopts intensification, step-down to carry out separation, collects product in separating still and must extract powder;
3. mix: the extraction powder of each traditional Chinese medicinal components is packed in the efficient asymmetric mixer of V-type in proportion, turn/min of speed of agitator 12, incorporation time 50min, obtains mixed powder;
4. capsule processed: mixed powder is added to make every quality in capsule loading machine be 0.5g capsule;
5. sterilization packaging: capsule is inserted after the lower 20min of irradiation of ultraviolet ray to packing in time.
Embodiment 3
(1) traditional Chinese medicinal components: Angelica Keiskei 40%, the root of large-flowered skullcap 20%, the root of kudzu vine 20%, ginkgo leaf 20%.
(2) preparation process is as follows:
1. get the raw materials ready: traditional Chinese medicinal components is carried out respectively to removal of impurities, dry, pulverize, cross 60 mesh sieves, extracting screen underflow, in obtaining
Medicinal powder;
2. extraction: adopt supercritical extracting equipment device, traditional Chinese medicine powder is put into respectively to supercritical CO
2in the extraction kettle of extraction equipment, add supercritical CO
2for extractant, 50 ℃ of extraction temperature, extracting pressure 15Mpa, extraction time is 4h, then adopts intensification, step-down to carry out separation, collects product in separating still and must extract powder;
3. mix: the extraction powder of each traditional Chinese medicinal components is packed in the efficient asymmetric mixer of V-type in proportion, turn/min of speed of agitator 12, incorporation time 60min, obtains mixed powder;
4. capsule processed: mixed powder is added to make every quality in capsule loading machine be 0.5g capsule;
5. sterilization packaging: capsule is inserted after the lower 20min of irradiation of ultraviolet ray to packing in time.
The above; embodiment is only that the preferred embodiment of the present invention is described; not scope of the present invention is limited; under the prerequisite of spirit that does not depart from the technology of the present invention; various distortion and improvement that this area engineers and technicians make technical scheme of the present invention, all should fall in the definite protection domain of claims of the present invention.
Claims (2)
1. Angelica Keiskei capsule and preparation method thereof, is characterized in that: traditional Chinese medicinal components is Angelica Keiskei 38%~40%, the root of large-flowered skullcap 20%~22%, the root of kudzu vine 18%~20%, ginkgo leaf 20%~22%.
2. a kind of Angelica Keiskei capsule according to claim 1 and preparation method thereof, is characterized in that: preparation process is as follows:
(1) get the raw materials ready: traditional Chinese medicinal components is carried out respectively to removal of impurities, dry, pulverize, cross 60 mesh sieves, extracting screen underflow obtains traditional Chinese medicine powder;
(2) extraction: adopt supercritical extracting equipment device, traditional Chinese medicine powder is put into respectively to supercritical CO
2in the extraction kettle of extraction equipment, add supercritical CO
2for extractant, 30 ℃~50 ℃ of extraction temperature, extracting pressure 15Mpa~30Mpa, extraction time is 4h~6h, then adopts intensification, step-down to carry out separation, collects product in separating still and must extract powder;
(3) mix: the extraction powder of each traditional Chinese medicinal components is packed in the efficient asymmetric mixer of V-type in proportion, turn/min of speed of agitator 12, incorporation time 40min~60 min, obtains mixed powder;
(4) capsule processed: mixed powder is added to make every quality in capsule loading machine be 0.5g capsule;
(5) sterilization packaging: capsule is inserted after the lower 20min of irradiation of ultraviolet ray to packing in time.
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104664369A (en) * | 2015-01-14 | 2015-06-03 | 厦门医学高等专科学校 | Angelica keiskei health food capable of reducing blood pressure and uric acid and preparation method of angelica keiskei health food |
CN104721620A (en) * | 2015-03-18 | 2015-06-24 | 苏州普罗达生物科技有限公司 | Leafy composition for enhancing immunity |
-
2014
- 2014-07-14 CN CN201410330284.0A patent/CN104116076A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104664369A (en) * | 2015-01-14 | 2015-06-03 | 厦门医学高等专科学校 | Angelica keiskei health food capable of reducing blood pressure and uric acid and preparation method of angelica keiskei health food |
CN104721620A (en) * | 2015-03-18 | 2015-06-24 | 苏州普罗达生物科技有限公司 | Leafy composition for enhancing immunity |
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