CN104107335A - Traditional Chinese medicine composition for oral administration and external application for treating canker sore - Google Patents
Traditional Chinese medicine composition for oral administration and external application for treating canker sore Download PDFInfo
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- CN104107335A CN104107335A CN201410375534.2A CN201410375534A CN104107335A CN 104107335 A CN104107335 A CN 104107335A CN 201410375534 A CN201410375534 A CN 201410375534A CN 104107335 A CN104107335 A CN 104107335A
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Abstract
The invention discloses a traditional Chinese medicine composition for oral administration and external application for treating canker sore. A traditional Chinese medicine for oral administration comprises the following components in parts by weight: 15-25 parts of Japanese honeysuckle stem, 15-25 parts of dahurian angelica root, 15-25 parts of sinkiang arnebia root, 15-25 parts of common bletilla tuber and 15-25 parts of indigo naturalis; and a traditional Chinese medicine for external application comprises the following components in parts by weight: 20-30 parts of Chinese gall, 20-30 parts of croton seed, 10-20 parts of radix scutellariae, 15-20 parts of borneol and 15-20 parts of liquoric root. The invention also discloses clinical curative effects of the traditional Chinese medicine composition. A curative effect result shows that the composition disclosed by the invention has the characteristics of fast action, significant effect, small side effect and low possibility of recurrence, and is especially suitable for medicaments for treating canker sore.
Description
Technical field
The present invention relates to a kind of oral ulcer Chinese medicine for the treatment of, be specifically related to a kind of Chinese medicine composition for the treatment of oral ulcer oral administration and externally.
Background technology
Cavity ulcer is commonly called as " cavity is got angry " or " aphtha ", is called again recurrent aphtha stomatitis, recurrent oral ulceration, is a kind of oral mucosa limitation ulcerative lesions that periodically outbreak is feature repeatedly of take, and can occur in any position of oral mucosa.The mucosa of locating with lip, cheek, soft palate or the gums etc. in oral cavity is common, there is single or a plurality of circular or oval ulcer differing in size, greyish white or the yellow pseudomembrane of surface coverage, concavity, clear border, around mucosa is red and micro-swollen, and the local causalgia of ulcer is obvious, has the feature of periodicity, recurrent, self limiting.At present, the cause of disease of oral ulcer and mechanism of causing a disease are still indefinite, and the inducement of oral ulcer may be local wound, psychentonia, food, medicine, hormonal readiness change and vitamin or trace element deficiency.Once formation oral ulcer, not only can affect patient orthobiosis, working and learning, sometimes even also can cause general disease.Although oral ulcer is not any serious disease, can bring the misery of feeling embarrassed to mention to patient, directly affect patient's feed, and then lower the resistance of the body, therefore can not be ignored.
Both at home and abroad to the oral ulcer western medicines that contain hormone that adopt, therapeutic effect is undesirable, and has very large side effect, cures the symptoms, not the disease more at present, and Drug therapy can cause many as problems such as hormone dependence, immunologic derangements for a long time.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition for the treatment of oral ulcer oral administration and externally, have rapid-action, effect is remarkable, side effect is little, be difficult for the features such as recurrence.
The technical solution used in the present invention is: for oral administration and external application Chinese medicine is combined treatment simultaneously, and Chinese medicine for oral administration be take its component of weight portion as Caulis Lonicerae 15-25 part, Radix Angelicae Dahuricae 15-25 part, Radix Arnebiae (Radix Lithospermi) 15-25 part, white taro 15-25 part, Indigo Naturalis 15-25 part; External application Chinese medicine be take its component of weight portion as Galla Chinensis 20-30 part, Fructus Crotonis 20-30 part, Radix Scutellariae 10-20 part, Borneolum Syntheticum 15-20 part, Radix Glycyrrhizae 15-20 part.
The present invention treats the crude drug preferred ingredient of the oral administration and externally Chinese medicine composition of oral ulcer, and Chinese medicine for oral administration be take its component of weight portion as Caulis Lonicerae 17-23 part, Radix Angelicae Dahuricae 17-23 part, Radix Arnebiae (Radix Lithospermi) 17-23 part, white taro 17-23 part, Indigo Naturalis 17-23 part; External application Chinese medicine be take its component of weight portion as Galla Chinensis 23-27 part, Fructus Crotonis 23-27 part, Radix Scutellariae 13-17 part, Borneolum Syntheticum 16-19 part, Radix Glycyrrhizae 16-19 part.
The present invention treats the crude drug preferred ingredient of the oral administration and externally Chinese medicine composition of oral ulcer, and Chinese medicine for oral administration be take its component of weight portion as Caulis Lonicerae 19-21 part, Radix Angelicae Dahuricae 19-21 part, Radix Arnebiae (Radix Lithospermi) 19-21 part, white taro 19-21 part, Indigo Naturalis 19-21 part; External application Chinese medicine be take its component of weight portion as Galla Chinensis 24-26 part, Fructus Crotonis 24-26 part, Radix Scutellariae 14-16 part, Borneolum Syntheticum 17-19 part, Radix Glycyrrhizae 16-18 part.
The present invention treats the crude drug preferred component of the oral administration and externally Chinese medicine composition of oral ulcer, and Chinese medicine for oral administration be take its component of weight portion as 20 parts of Caulis Loniceraes, 20 parts of the Radixs Angelicae Dahuricae, 20 parts of Radix Arnebiae (Radix Lithospermi)s, 20 parts of white taros, 20 parts of Indigo Naturaliss; External application Chinese medicine be take its component of weight portion as 25 parts of Galla Chinensiss, 25 parts of Fructus Crotonis, 15 parts of Radix Scutellariae, 18 parts of Borneolum Syntheticums, 17 parts, Radix Glycyrrhizae.
The present invention treats the preparation method of oral ulcer oral administration and externally Chinese medicine composition, and the preparation method of Chinese medicine for oral administration is: get it filled in proportion after material, clean up to put into and decoct utensil marmite, add decocting and endure; The preparation method of external application Chinese medicine is: take in proportion medical material, clean up and put into pulverizer and pulverize 100 object medicated powder, further make pad pasting after sterilization.
The present invention treats the oral administration and externally compositions of oral ulcer, there is following pharmacology: Caulis Lonicerae heat-clearing and toxic substances removing, dispelling wind dredging collateral, Radix Angelicae Dahuricae pain relieving, swollen, the dampness of detumescence row, Radix Arnebiae (Radix Lithospermi) removing heat from blood, the rash of invigorating blood circulation, detoxify, white taro hemostasia and detumescence, promoting tissue regeneration and ulcer healing, Indigo Naturalis heat-clearing and toxic substances removing, removing heat from blood arresting convulsion, Galla Chinensis astringe the lung pathogenic fire reducing, puckery hemostasis, arresting sweating hemostasis, removing dampness sore, Fructus Crotonis erosion slough, treatment sore, Radix Scutellariae heat clearing and damp drying, eliminating fire and detoxication, Borneolum Syntheticum heat-clearing and toxic substances removing, erosion prevention and muscle growing, Radix Glycyrrhizae invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
Compare with existing medicine, this composition of medicine has the following feature that has: rapid-action, effect is remarkable, side effect is little, be difficult for recurrence.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is further described.
Embodiment 1
First, by following component, take oral administration and externally raw material of Chinese medicine, Chinese medicine for oral administration be take its component of weight portion as 25 parts of Caulis Loniceraes, 25 parts of the Radixs Angelicae Dahuricae, 25 parts of Radix Arnebiae (Radix Lithospermi)s, 15 parts of white taros, 20 parts of Indigo Naturaliss; External application Chinese medicine be take its component of weight portion as 30 parts of Galla Chinensiss, 30 parts of Fructus Crotonis, 10 parts of Radix Scutellariae, 15 parts of Borneolum Syntheticums, 15 parts, Radix Glycyrrhizae.
Then, prepare Chinese medicine, the preparation method of Chinese medicine for oral administration is: get it filled in proportion after material, clean up to put into and decoct utensil marmite, add decocting and be boiled into dope; The preparation method of external application Chinese medicine is: take in proportion medical material, clean up and put into pulverizer and pulverize 100 object medicated powder, further make pad pasting after sterilization.
Finally, instructions of taking, oral administration and externally is combined treatment simultaneously.Chinese medicine for oral administration, oral liquid medicine, once-a-day; External application Chinese medicine, external application medicine film, three times on the one; 3 days courses for the treatment of, use continuously 2 courses for the treatment of.
Embodiment 2
First, by following component, take oral administration and externally raw material of Chinese medicine, Chinese medicine for oral administration be take its component of weight portion as 15 parts of Caulis Loniceraes, 15 parts of the Radixs Angelicae Dahuricae, 20 parts of Radix Arnebiae (Radix Lithospermi)s, 25 parts of white taros, 25 parts of Indigo Naturaliss; External application Chinese medicine be take its component of weight portion as 20 parts of Galla Chinensiss, 20 parts of Fructus Crotonis, 20 parts of Radix Scutellariae, 20 parts of Borneolum Syntheticums, 20 parts, Radix Glycyrrhizae.
Then, prepare Chinese medicine, the preparation method of Chinese medicine for oral administration is: get it filled in proportion after material, clean up to put into and decoct utensil marmite, add decocting and be boiled into dope; The preparation method of external application Chinese medicine is: take in proportion medical material, clean up and put into pulverizer and pulverize 100 object medicated powder, further make pad pasting after sterilization.
Finally, instructions of taking, oral administration and externally is combined treatment simultaneously.Chinese medicine for oral administration, oral liquid medicine, once-a-day; External application Chinese medicine, external application medicine film, three times on the one; 3 days courses for the treatment of, use continuously 2 courses for the treatment of.
Embodiment 3
First, by following component, take oral administration and externally raw material of Chinese medicine, Chinese medicine for oral administration be take its component of weight portion and be take its component of weight portion as 20 parts of Caulis Loniceraes, 20 parts of the Radixs Angelicae Dahuricae, 20 parts of Radix Arnebiae (Radix Lithospermi)s, 20 parts of white taros, 20 parts of Indigo Naturaliss as: Chinese medicine for oral administration; External application Chinese medicine be take its component of weight portion as 25 parts of Galla Chinensiss, 25 parts of Fructus Crotonis, 15 parts of Radix Scutellariae, 18 parts of Borneolum Syntheticums, 17 parts, Radix Glycyrrhizae.
Then, prepare Chinese medicine, the preparation method of Chinese medicine for oral administration is: get it filled in proportion after material, clean up to put into and decoct utensil marmite, add decocting and be boiled into dope; The preparation method of external application Chinese medicine is: take in proportion medical material, clean up and put into pulverizer and pulverize 100 object medicated powder, further make pad pasting after sterilization.
Finally, instructions of taking, oral administration and externally is combined treatment simultaneously.Chinese medicine for oral administration, oral liquid medicine, once-a-day; External application Chinese medicine, external application medicine film, three times on the one; 3 days courses for the treatment of, use continuously 2 courses for the treatment of.
It should be pointed out that above case is only the representational example of the present invention.Obviously, technical scheme of the present invention is not limited to above-described embodiment, can also have many degeneration.
The clinical observation on the therapeutic effect test of oral administration and externally composition of medicine treatment oral ulcer of the present invention, selects 120 routine oral ulcer patients to carry out clinical observation to the curative effect of medicine of the present invention.All cases all, according to the diagnostic criteria of < < new Chinese medicine guideline of clinical investigations (the 3rd volume) > >, is diagnosed as oral ulcer.
Above-mentioned 120 routine patients are divided into 6 groups at random, that is: 1 group for the treatment of, 2 groups of treatments, 3 groups of treatments, 1 group of contrast, 2 groups of contrasts, 3 groups of contrasts, every group of each 20 examples; Treat 1 group, treatment 2 groups, treatment 3 groups adopt respectively the oral administration and externally composition of medicine of embodiment 1, embodiment 2, embodiment 3 to use treatment simultaneously; Contrast 1 group and only adopt separately the medicinal liquid in embodiment 1, oral, every day 1 time, within 3 days, be a course for the treatment of, use continuously 3 courses for the treatment of; Contrasting 2 groups of disposable pad pasting treatments that only adopt separately in embodiment 1,3 days is a course for the treatment of, uses continuously 3 courses for the treatment of; Contrast 3 groups and adopt anti-inflammation drugs treatment, oral, every day 3 times, each 23 days is a course for the treatment of, uses continuously 3 courses for the treatment of; All case period in a medicine are withdrawn other related drugs and other treatment.
The clinical observation on the therapeutic effect result of the test of oral administration and externally composition of medicine treatment oral ulcer of the present invention is as shown in the table:
Clinical observation on the therapeutic effect result shows, the obvious excellent and matched group of composition of medicine treatment curative effect for the treatment of group employing oral administration and externally of the present invention, and two group differences are remarkable.
Claims (4)
1. a Chinese medicine composition for the treatment of oral ulcer oral administration and externally, is characterized in that, Chinese medicine for oral administration be take its component of weight portion as Caulis Lonicerae 15-25 part, Radix Angelicae Dahuricae 15-25 part, Radix Arnebiae (Radix Lithospermi) 15-25 part, white taro 15-25 part, Indigo Naturalis 15-25 part; External application Chinese medicine be take its component of weight portion as Galla Chinensis 20-30 part, Fructus Crotonis 20-30 part, Radix Scutellariae 10-20 part, Borneolum Syntheticum 15-20 part, Radix Glycyrrhizae 15-20 part.
2. the Chinese medicine composition for the treatment of oral ulcer oral administration and externally according to claim 1, is characterized in that, Chinese medicine for oral administration be take its component of weight portion as Caulis Lonicerae 17-23 part, Radix Angelicae Dahuricae 17-23 part, Radix Arnebiae (Radix Lithospermi) 17-23 part, white taro 17-23 part, Indigo Naturalis 17-23 part; External application Chinese medicine be take its component of weight portion as Galla Chinensis 23-27 part, Fructus Crotonis 23-27 part, Radix Scutellariae 13-17 part, Borneolum Syntheticum 16-19 part, Radix Glycyrrhizae 16-19 part.
3. the Chinese medicine composition for the treatment of oral ulcer oral administration and externally according to claim 2, is characterized in that, Chinese medicine for oral administration be take its component of weight portion as Caulis Lonicerae 19-21 part, Radix Angelicae Dahuricae 19-21 part, Radix Arnebiae (Radix Lithospermi) 19-21 part, white taro 19-21 part, Indigo Naturalis 19-21 part; External application Chinese medicine be take its component of weight portion as Galla Chinensis 24-26 part, Fructus Crotonis 24-26 part, Radix Scutellariae 14-16 part, Borneolum Syntheticum 17-19 part, Radix Glycyrrhizae 16-18 part.
4. the Chinese medicine composition for the treatment of oral ulcer oral administration and externally according to claim 3, is characterized in that, Chinese medicine for oral administration be take its component of weight portion as 20 parts of Caulis Loniceraes, 20 parts of the Radixs Angelicae Dahuricae, 20 parts of Radix Arnebiae (Radix Lithospermi)s, 20 parts of white taros, 20 parts of Indigo Naturaliss; External application Chinese medicine be take its component of weight portion as 25 parts of Galla Chinensiss, 25 parts of Fructus Crotonis, 15 parts of Radix Scutellariae, 18 parts of Borneolum Syntheticums, 17 parts, Radix Glycyrrhizae.
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| CN201410375534.2A CN104107335A (en) | 2014-07-31 | 2014-07-31 | Traditional Chinese medicine composition for oral administration and external application for treating canker sore |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104645101A (en) * | 2015-01-29 | 2015-05-27 | 吴丹 | Medicine used for treating spleen-stomach fervor-type dental ulcer and preparation method of medicine |
| CN106138721A (en) * | 2015-07-17 | 2016-11-23 | 杨蒙健 | A kind of external application Chinese medicine compound preparation treating recurrent oral ulceration and preparation method |
| CN110876779A (en) * | 2019-12-23 | 2020-03-13 | 山东中医药大学 | Traditional Chinese medicine composition for treating oral ulcer and preparation method and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102091116A (en) * | 2011-03-18 | 2011-06-15 | 魏绍良 | Medicine membrane for treating dental ulcer and preparation method thereof |
| CN102441114A (en) * | 2011-12-20 | 2012-05-09 | 江苏省中医药研究院 | Traditional Chinese medicine composition for treating oral ulcer |
-
2014
- 2014-07-31 CN CN201410375534.2A patent/CN104107335A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102091116A (en) * | 2011-03-18 | 2011-06-15 | 魏绍良 | Medicine membrane for treating dental ulcer and preparation method thereof |
| CN102441114A (en) * | 2011-12-20 | 2012-05-09 | 江苏省中医药研究院 | Traditional Chinese medicine composition for treating oral ulcer |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104645101A (en) * | 2015-01-29 | 2015-05-27 | 吴丹 | Medicine used for treating spleen-stomach fervor-type dental ulcer and preparation method of medicine |
| CN106138721A (en) * | 2015-07-17 | 2016-11-23 | 杨蒙健 | A kind of external application Chinese medicine compound preparation treating recurrent oral ulceration and preparation method |
| CN110876779A (en) * | 2019-12-23 | 2020-03-13 | 山东中医药大学 | Traditional Chinese medicine composition for treating oral ulcer and preparation method and application thereof |
| CN110876779B (en) * | 2019-12-23 | 2021-11-09 | 山东中医药大学 | Traditional Chinese medicine composition for treating oral ulcer and preparation method and application thereof |
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