CN104083710A - Traditional Chinese medicine preparation for treating scleroderma - Google Patents
Traditional Chinese medicine preparation for treating scleroderma Download PDFInfo
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- CN104083710A CN104083710A CN201410270950.6A CN201410270950A CN104083710A CN 104083710 A CN104083710 A CN 104083710A CN 201410270950 A CN201410270950 A CN 201410270950A CN 104083710 A CN104083710 A CN 104083710A
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Abstract
A traditional Chinese medicine preparation for treating scleroderma comprises the raw materials: 30 parts of radix salviae miltiorrhizae, 15 parts of caulis spatholobi, 15 parts of radix angelicae sinensis, 15 parts of radix curcumae, 30 parts of radix rehmanniae, 30 parts of radix rehmanniae preparata, 30 parts of radix astragali, 10 parts of ramulus cinnamomi, 12 parts of radix paeoniae rubra, 10 parts of flos carthami, 10 parts of rhizoma chuanxiong and 15 parts of rhizoma curcumae. A preparation method for the traditional Chinese medicine preparation comprises: weighing 30 parts of radix salviae miltiorrhizae, 15 parts of caulis spatholobi, 15 parts of radix angelicae sinensis, 15 parts of radix curcumae, 30 parts of radix rehmanniae, 30 parts of radix rehmanniae preparata, 30 parts of radix astragali, 10 parts of ramulus cinnamomi, 12 parts of radix paeoniae rubra, 10 parts of flos carthami, 10 parts of rhizoma chuanxiong and 15 parts of rhizoma curcumae, respectively preparing decoction pieces, performing stewing sterilization for 30-60 min by using a pressure cooker, and airing to dry to obtain aseptic raw materials; and preparing the traditional Chinese medicine preparation from the obtained aseptic raw materials. The traditional Chinese medicine preparation has the efficacy of resisting bacteria and diminishing inflammation, activating blood and detoxifying, nourishing blood and moistening skin, and improving tissue nutrition, and is used to treat scleroderma.
Description
Technical field
The present invention relates to field of traditional Chinese; Be specifically related to a kind of sclerodermatous Chinese medicine preparation for the treatment of.
Background technology
Scleroderma is a kind of general connective tissue disease.The cause of disease is relevant with dysimmunity with heredity, is mainly in the women of child-bearing age.With limitation or diffusivity pachyderma and fiber, turn to feature clinically, and involve the connective tissue disease of the internal organs such as the heart, lung, kidney, digestive tract.The position of involving according to degree and the pathological changes of its dermatosis, can be divided into limitation and systemic amphitypy.Local scleroderma main manifestations is skin sclerosis; Systemic sclerosis, is called again systemic sclerosis, can involve skin, synovial membrane and internal organs, particularly gastrointestinal tract, lung, kidney, the heart, blood vessel, Musculoskeletal etc., causes the functional defect of corresponding organs.Each age all can fall ill, but take 20～50 years old as onset peak.Women's sickness rate is 3～4 times of male.Therapeutic Principle is for warming, antiinflammatory, anticoagulant and blood vessel dilating in early days and give extract oral treatment.The other medicines for the treatment of this disease in prior art exist therapeutic effect not obvious, the technological deficiency that side effect is large.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine preparation that anti-inflammation, promoting blood circulation and detoxication, blood-nourishing skin-moisturizing improve histotrophic nutrition effect that has, be used for the treatment of scleroderma.
Technical scheme of the present invention: the raw material of Chinese medicine preparation of the present invention and each component consumption thereof are groped in a large number to sum up through inventor and drawn, each component amount all has good effect within the scope of this: 30 parts of Radix Salviae Miltiorrhizaes, 15 parts of Caulis Spatholobis, 15 parts of Radix Angelicae Sinensis, 15 parts of Radix Curcumaes, 30 parts, the Radix Rehmanniae, 30 parts of Radix Rehmanniae Preparata, 30 parts of the Radixs Astragali, 10 parts of Ramulus Cinnamomi, 12 parts of Radix Paeoniae Rubra, 10 parts, Flos Carthami, 10 parts of Rhizoma Chuanxiongs, 15 parts of Rhizoma Curcumae.
For reaching anti-inflammation, promoting blood circulation and detoxication, blood-nourishing skin-moisturizing, improve histotrophic nutrition effect, the present invention selects 15 parts of 30 parts of Radix Salviae Miltiorrhizaes, 15 parts of Caulis Spatholobis, 15 parts of Radix Angelicae Sinensis, 15 parts of Radix Curcumaes, 30 parts, the Radix Rehmanniae, 30 parts of Radix Rehmanniae Preparata, 30 parts of the Radixs Astragali, 10 parts of Ramulus Cinnamomi, 12 parts of Radix Paeoniae Rubra, 10 parts, Flos Carthami, 10 parts of Rhizoma Chuanxiongs, Rhizoma Curcumae to combine, by these drug regimens, make each efficacy of drugs produce synergism, thereby can effectively treat scleroderma.In the raw materials of traditional Chinese medicinal materials of choosing, its effect and pharmacological action respectively:
Radix Salviae Miltiorrhizae: be dicotyledon Labiatae, dry root and rhizome.Effect: promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind.For costa sternales hypochondriac pain, rheumatic arthralgia, lump in the abdomen caking, skin infection swells and ache, tumbling down is grieved, menoxenia, amenorrhea dysmenorrhea, puerperal stasis of blood pain etc.Treatment costa sternales pain, lump in the abdomen caking, and menoxenia, amenorrhea dysmenorrhoea have good effect.Radix Salviae Miltiorrhizae can make aorta atheromatous plaque formation area obviously reduce, serum total cholesterol, triglyceride, all decreases to some degree.
Caulis Spatholobi: rattan is containing epifriedelanol, daucosterol, cupreol, 7-ketone group-cupreol (7-oxo-β-sitosterol); formoononetin, ononin, prunusetin., afromosin; Dai, 3,7-dihydroxy-6-melonia flavonol, epicatechin; Isoliquiritigenin 3,4,2 '; 4 '-tetrahydroxy chalcone derivative, Licochalcone A, lucerne pig phenol; protocatechuic acid, 9-methoxyl group coumestrol, Semen Cajani isoflavone.The modern Practical Chinese medicinal > of < < >: be the hematonic of robustness, be applicable to the neural paralysis disease of anemia, as limbs and soreness of waist and knee joint, apathetic etc.Again for menoxenia, menstruation apolipsis etc., have the effect of invigorating blood circulation analgesia.
Radix Angelicae Sinensis: [chemical composition] contains basic lactone, n-butene acyl lactone, ferulic acid, nicotinic acid, sucrose and several amino acids, and sesquiterpenoids etc.[meridian distribution of property and flavor] is warm in nature, hides sweet, pungent.Return liver, the heart, spleen channel.[function cures mainly] enriched blood and invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.
Radix Curcumae: [medical value]: Chinese medicine: Radix Curcumae Radix Curcumae Aromaticae source is the tuber of zingiberaceous plant Radix Curcumae.Gather and process and take tuber in winter or early spring, clean, boil and dry.[nature and flavor with return through]: pungent, bitter, cold.Return liver, the heart, lung meridian.[function cures mainly]: promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire, promoting the function of the gallbladder to alleviate jaundice.For amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, calentura coma, epilepsy is gone mad, jaundice dark coloured urine.
The Radix Rehmanniae: be also Radix Rehmanniae, the fresh or dry tuber of Scrophulariaceae herbaceos perennial Radix Rehmanniae Rehmannia glutinosa Libosch..Main product is in China Henan, Hebei, the Inner Mongol and northeast.There is cultivation most areas.Excavate autumn, using fresh herb or dry sliced raw using.Radix Rehmanniae Preparata is that Radix Rehmanniae is mixed steaming to inside and outside darkish complexion, glossy through adding yellow wine, or directly steaming to black profit forms.Cutting sheet uses.The effect that Radix Rehmanniae has clearing away heat and cooling blood, tonifying YIN to promote the production of body fluid.
Radix Rehmanniae Preparata: sweet in the mouth slightly warm in nature, return liver, kidney channel, there is nourishing the blood and yin, the effect of vital essence replenishing and marrow benifiting, is applicable to syndrome of deficiency of blood, menoxenia, syndrome of yin deficiency of liver and kidney, diabete, blood and essence asthenia card etc.Radix Rehmanniae Preparata is the important drugs of nourishing the liver and kidney, not only can nourishing the blood and yin, and can fill out marrow by spermatogenesis.The traditional Chinese medical science thinks that essence and blood is material base the most basic in human body, and essence and blood abundance hepatic and renal function is normal, and body shows strong functional status.Otherwise having a dizzy spell appears in human body asthenia of essence and blood, soreness of the waist and knees, deafness and tinnitus, early whitening of beard and hair, geromorphism, sexual hypofunction etc.Modern medicine study confirms, contains sitosterol, mannitol, catalpol, rehmanin, saccharide, glycoside and multivitamin and mineral etc. in Radix Rehmanniae Preparata.Radix Rehmanniae Preparata has inhibition lipid peroxidation, improves the effects such as activities of antioxidant enzymes, and can blood pressure lowering, blood fat reducing, inhibition thrombosis, improve myocardial ischemia etc.
The Radix Astragali: the Chinese crude drug Radix Astragali is the root of leguminous herbaceous plant's Radix Astagali, Radix Astragali, has the effects such as invigorating QI to consolidate the body surface resistance, diuretic detumescent, expelling pus and toxin by strengthening QI, granulation promoting.The medicinal history of existing more than 2000 year so far of the Radix Astragali, modern study, the Radix Astragali is containing various trace elements such as Saponin, sucrose, polysaccharide, several amino acids, folic acid and selenium, zinc, copper.Have enhancing human body immunity function, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely.
Ramulus Cinnamomi: be the dry twig of Lauraceae aiphyllium plant Cortex Cinnamomi.[curing mainly] expelling cold and relieving exterior syndrome; Promoting the flow of QI-blood by warming the meridian; Activating YANG and prormoting functioning of QI.Main exterior syndrome due to wind-cold; Arthralgia due to cold-dampnes; Extreme cold of the limbs; Amenorrhea dysmenorrhea; Lump in the abdomen caking; The thoracic obstruction; Cardiopalmus; Phlegm retention; Dysuria.For anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.[effect] diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, dispersing cold for relieving pain.
Radix Paeoniae Rubra: function, clots absorbing, pain relieving, removing heat from blood, detumescence.Cure mainly: control that the stagnant amenorrhea of the stasis of blood, hernia abdominal mass gather, stomachache, hypochondriac pain, epistaxis, dysentery, discharging fresh blood stool, conjunctival congestion, carbuncle, injury from falling down.
Flos Carthami: [chemical composition] is containing carthamin, neocarthamin, Flos Carthami quinone glycoside, Flos Carthami polysaccharide, Palmic acid, cinnamic acid, lauric acid.[nature and flavor] are warm in nature, acrid in the mouth.[function cures mainly] promoting blood circulation to restore menstrual flow, scattered silt pain relieving, for amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache.
Rhizoma Chuanxiong: acrid in the mouth, warm in nature.Return liver, gallbladder, pericardium channel.[function with cure mainly] blood-activating and qi-promoting, wind-expelling pain-stopping.Be used for pacifying nerve, positive wind syndrome of head headache, lump in the abdomen stomachache, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Rhizoma Curcumae: [Chinese crude drug formal name used at school]: Rhizoma Curcumae (Rhizoma Curcumae).[English name]: Aemginous Turmeric Rhizome.Rhizome claims " Rhizoma Curcumae ", hyoscine, cure mainly " lump in the abdomen, gathers for coagulation of QI-blood, trusted subordinate's distending pain, and dyspepsia does not disappear, women's blood stasis amenorrhea, and traumatic injury is had a pain." tuber claims " green filament Radix Curcumae ".Rhizome is containing volatile oil 1-1.5%.In oil, main component is sesquiterpene alcohols, α-camphorene and press olein.In addition still starch-containing, mucus and resin etc.[function cures mainly] circulation of qi promoting removing blood stasis, removing food stagnancy pain relieving.For Dan abdominal mass mass in the abdomen, blood stasis amenorrhea, food stagnation distending pain; Early cervical carcinoma.[extracts] < < Chinese Pharmacopoeia > >.Antibacterial action: Rhizoma Curcumae volatile oil in vitro can suppress staphylococcus aureus.The growth of beta hemolytic streptococcus, escherichia coli, Bacillus typhi, vibrio cholera etc.Antiinflammatory action: the peritonitis that mouse gavaging the essential oil from Curcuma wenyujin 200mg/kg Dichlorodiphenyl Acetate produces has the inhibitory action showing very much, mouse peritoneal injection the essential oil from Curcuma wenyujin 200mg/kg has obvious inhibitory action to scald property local edema, ear's inflammation that lumbar injection 100m/kg causes Oleum Tiglii has obvious inhibitory action, rats by intraperitoneal injection volatile oil 75mg/kg/ days, had obvious inhibitory action to subcutaneous granuloma induced by implantation of cotton pellets hypertrophy after 9 days.
For Da Gengjia result of use, the present invention also provides the preparation method of this Chinese medicine preparation; Its preparation method: take 15 parts of 30 parts of raw material Radix Salviae Miltiorrhizaes, 15 parts of Caulis Spatholobis, 15 parts of Radix Angelicae Sinensis, 15 parts of Radix Curcumaes, 30 parts, the Radix Rehmanniae, 30 parts of Radix Rehmanniae Preparata, 30 parts of the Radixs Astragali, 10 parts of Ramulus Cinnamomi, 12 parts of Radix Paeoniae Rubra, 10 parts, Flos Carthami, 10 parts of Rhizoma Chuanxiongs, Rhizoma Curcumae and make respectively decoction pieces, through pressure cooker cooking disinfection 30-60 minute, dry, obtain aseptic raw material; The aseptic raw material obtaining is made Chinese medicine preparation and get final product.
Chinese medicine for outer use of the present invention has anti-inflammation, promoting blood circulation and detoxication, blood-nourishing skin-moisturizing and improves histotrophic nutrition effect, is used for the treatment of scleroderma.So far, still do not find report and the application of relevant Chinese medicine preparation of the present invention.The inventor, through research repeatedly, and by the checking repeatedly of clinical trial, has finally found the Chinese medicine preparation that has better curative effect, thereby has completed the present invention.
Specific implementation method
Treatment scleroderma of the present invention, its raw material is: 30 parts of Radix Salviae Miltiorrhizaes, 15 parts of Caulis Spatholobis, 15 parts of Radix Angelicae Sinensis, 15 parts of Radix Curcumaes, 30 parts, the Radix Rehmanniae, 30 parts of Radix Rehmanniae Preparata, 30 parts of the Radixs Astragali, 10 parts of Ramulus Cinnamomi, 12 parts of Radix Paeoniae Rubra, 10 parts, Flos Carthami, 10 parts of Rhizoma Chuanxiongs, 15 parts of Rhizoma Curcumae.
Its preparation method: take 15 parts of 30 parts of raw material Radix Salviae Miltiorrhizaes, 15 parts of Caulis Spatholobis, 15 parts of Radix Angelicae Sinensis, 15 parts of Radix Curcumaes, 30 parts, the Radix Rehmanniae, 30 parts of Radix Rehmanniae Preparata, 30 parts of the Radixs Astragali, 10 parts of Ramulus Cinnamomi, 12 parts of Radix Paeoniae Rubra, 10 parts, Flos Carthami, 10 parts of Rhizoma Chuanxiongs, Rhizoma Curcumae and make respectively decoction pieces, through pressure cooker cooking disinfection 30-60 minute, dry, obtain aseptic raw material; The aseptic raw material obtaining is made Chinese medicine preparation and get final product.
Claims (2)
1. the sclerodermatous Chinese medicine preparation for the treatment of, is characterized in that: its raw material is; 30 parts of Radix Salviae Miltiorrhizaes, 15 parts of Caulis Spatholobis, 15 parts of Radix Angelicae Sinensis, 15 parts of Radix Curcumaes, 30 parts, the Radix Rehmanniae, 30 parts of Radix Rehmanniae Preparata, 30 parts of the Radixs Astragali, 10 parts of Ramulus Cinnamomi, 12 parts of Radix Paeoniae Rubra, 10 parts, Flos Carthami, 10 parts of Rhizoma Chuanxiongs, 15 parts of Rhizoma Curcumae.
2. according to the sclerodermatous Chinese medicine preparation for the treatment of claimed in claim 1, it is characterized in that: its preparation method: take 15 parts of 30 parts of raw material Radix Salviae Miltiorrhizaes, 15 parts of Caulis Spatholobis, 15 parts of Radix Angelicae Sinensis, 15 parts of Radix Curcumaes, 30 parts, the Radix Rehmanniae, 30 parts of Radix Rehmanniae Preparata, 30 parts of the Radixs Astragali, 10 parts of Ramulus Cinnamomi, 12 parts of Radix Paeoniae Rubra, 10 parts, Flos Carthami, 10 parts of Rhizoma Chuanxiongs, Rhizoma Curcumae and do not make decoction pieces, through pressure cooker cooking disinfection 30-60 minute, dry, obtain aseptic raw material; The aseptic raw material obtaining is made Chinese medicine preparation and get final product.
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| CN201410270950.6A CN104083710A (en) | 2014-06-03 | 2014-06-03 | Traditional Chinese medicine preparation for treating scleroderma |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104524030A (en) * | 2015-01-09 | 2015-04-22 | 杨茹芹 | Traditional Chinese medicine composition for treating deficient vital qi lingering pathogen type scleroderma |
| CN104784634A (en) * | 2015-03-31 | 2015-07-22 | 刘凤伟 | Traditional Chinese medicine preparation for treating diffuse systemic scleroderma |
-
2014
- 2014-06-03 CN CN201410270950.6A patent/CN104083710A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104524030A (en) * | 2015-01-09 | 2015-04-22 | 杨茹芹 | Traditional Chinese medicine composition for treating deficient vital qi lingering pathogen type scleroderma |
| CN104784634A (en) * | 2015-03-31 | 2015-07-22 | 刘凤伟 | Traditional Chinese medicine preparation for treating diffuse systemic scleroderma |
| CN104784634B (en) * | 2015-03-31 | 2018-12-14 | 刘凤伟 | A kind of Chinese materia medica preparation for treating diffusivity systemic scleroderma |
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Application publication date: 20141008 |