CN104069394A - Medicine composition for treating osteoproliferation - Google Patents

Medicine composition for treating osteoproliferation Download PDF

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Publication number
CN104069394A
CN104069394A CN201410363657.4A CN201410363657A CN104069394A CN 104069394 A CN104069394 A CN 104069394A CN 201410363657 A CN201410363657 A CN 201410363657A CN 104069394 A CN104069394 A CN 104069394A
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radix
medicine composition
herba
hyperosteogeny
pharmaceutical composition
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CN201410363657.4A
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汪永华
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Abstract

The invention discloses a medicine composition for treating osteoproliferation, which is prepared from the following medicinal materials by mass: 30-45g olibanum, 15-25g myrrh, 5-15g panax notoginseng, 15g loranthus parasiticus, 15g achyranthes bidentata, 15g ligusticum wallichii, 15g radix dipsaci, 15g radix rehmanniae, 30g akebiaquinata, 15g cortex moutan radicis, 25g sarcandra glabra, 20g coix seed, 3g herba asari cum radice and 2g Chinese alangium root. A preparation method comprises the following steps of cleaning the medicinal materials respectively, drying with hot air, breaking into blocks, disinfecting with ultraviolet rays, after mixing according to a proportion in a formula, putting into a container, adding liquor soaking and roasting, then drying with moderate heat, grinding, pulverizing, mixing uniformly to form powder, or preparing a pill or a capsule according to the conventional pharmaceutical technology. The medicine composition has the following advantages that the medicine composition has a wide medicine source, is low in cost and particularly obvious in curative effect, takes effect quickly, has effects of expelling wind, removing dampness, promoting blood circulation to stop pain, strengthening tendons and dredging collaterals on various populations and is applicable to treating patients with the osteoproliferation.

Description

A kind of pharmaceutical composition for the treatment of hyperosteogeny
Technical field
The present invention is relevant with medicinal preparation, in particular to the medicine for the treatment of hyperosteogeny.
Background technology
Bone matrix hyperplasia is called again hyperplastic osteoarthritis, osteoarthritis, degenerated arthrosis, senile arthritis, hypertrophiarthritis, due to soft tissue degeneration, degenerations such as the cartilage that forms joint, intervertebral disc, ligaments, edge, joint forms bony spur, the variations such as synovial membrane is plump, and there is osteoclasia, cause insecondary hyperosteogeny, cause joint deformity, when being subject to abnormal load, cause arthralgia, a kind of disease of the symptoms such as limitation of activity.Two kinds of hyperostosis constitutional estranged and Secondary cases.The traditional Chinese medical science thinks that primary disease is relevant with wound, strain, obstruction of collaterals by blood stasis, the damp that is affected by the cold, phlegm resistance, caused by liver and kidney deficiency etc.Hyperosteogeny can cause patient's misery and life inconvenience.
In recent years, with the Chinese patent application part of the prescription therapeutic hyperosteogeny of Chinese medicinal herbs, hundreds of have been reached.For example: No. 201210284189.2 < < pure Chinese medicine > > who treats various hyperosteogeny, No. 201310068903.9 < < herb liquid > > who treats hyperosteogeny, No. 201310058722.8 < < Chinese drugs agentia > > who treats hyperosteogeny, the external application Chinese medicine of the Chinese medicine for external application of No. 201310031123.7 < < treatment hyperosteogenys and preparation method thereof > > and No. 201310079497.6 < < treatment hyperosteogenys and preparation method thereof > > etc.These patent applications all disclose the Chinese herbal medicine for the treatment of hyperosteogeny, but its curative effect there is no report.Therefore people are still at exploitation renewal, more effective medicine.
Summary of the invention
The present invention aims to provide a kind of medicine for the treatment of hyperosteogeny, to increase the types of drugs for the treatment of hyperosteogeny, and take the health service that the specially good effect of its treatment is people.
The pharmaceutical composition for the treatment of hyperosteogeny of the present invention is made by the medical material of following quality proportioning:
Olibanum 30~45, Myrrha 15~25, Radix Notoginseng 5~15, Herba Taxilli 15, Radix Achyranthis Bidentatae 15, Rhizoma Chuanxiong 15, Radix Dipsaci 15, the Radix Rehmanniae 15, Caulis Akebiae 30, Cortex Moutan 15, Herba Pileae Scriptae 25, Semen Coicis 20, Herba Asari 3, Radix Alangii 2.
In above-mentioned medical material:
olibanum,for olive subject plant Boswellia carterii Birdw ( boswellia carterii) gum resin, bitter in the mouth is pungent, warm in nature, has regulating qi and activating blood, analgesic therapy chases after malicious effect (seeing 1379 pages of < < Chinese crude drug voluminous dictionary > >);
myrrhafor olive subject plant myrrh ( commiphora myrrha) gum resin, bitter in the mouth, property is flat, the blood that can fall apart, blood stasis removing, subsides a swelling, analgesic therapy (seeing 1167 pages of < < Chinese medicine voluminous dictionary > >);
radix Notoginseng, be Araliaceae Panax pseudoginseng ( panax pseudo-ginseng) root, it is warm in nature, sweet and slightly bitter taste can hemostasis, scattered silt, detumescence, analgesic therapy (seeing 54 pages of < < Chinese medicine voluminous dictionary > >);
herba Taxilli,for Loranthaceae plant Herba Taxilli ( loranthus parasiticus) branch and leaf, bitter but sweet flavor, property is flat, can invigorating the liver and kidney, bone and muscle strengthening, except rheumatism, the meridian dredging (seeing 1917 pages of < < Chinese medicine voluminous dictionary > >);
radix Achyranthis Bidentataefor amaranthaceous plant Radix Achyranthis Bidentatae ( achyranthes bidentata) root, sweet in the mouth picric acid, property is flat, has the effect (seeing 417 pages of < < Chinese medicine voluminous dictionary > >) of dissipating blood stasis blood, subduing inflammation;
rhizoma Chuanxiongwei San section plant Rhizoma Chuanxiong ( ligusticum chuanxiong) rhizome, acrid in the mouth, warm in nature, can activating QI to alleviate the depression, dispeiling pathogenic wind and removing dampness.Promoting blood circulation and stopping pain (seeing 220 pages of < < Chinese medicine voluminous dictionary > >);
Radix Dipsaci be Dipsacaceae plant Radix Dipsaci ( dipsacus asperwall.ex Henry) dry root, bitter in the mouth is pungent, slightly warm in nature; Energy invigorating the liver and kidney, bone and muscle strengthening, continuous injured, only metrorrhagia (seeing 2010 editions one 309 pages of < < Pharmacopoeia of People's Republic of China > >);
the Radix Rehmanniae, i.e. Radix Rehmanniae, for scrophulariaceae rehmannia glutinosa plant ( rehmannia glutinosa) fresh rhizome, sweet-bitter flavor, cold in nature, has heat clearing away, removing heat from blood, an effect of promoting the production of body fluid (seeing 2568 pages of < < Chinese medicine voluminous dictionary > >);
caulis Akebiaefor plants of Lardizabalaceae Caulis Akebiae ( akebia trifoliata) woody stems, bitter in the mouth, cool in nature, has pathogenic fire purging row water, promoting blood circulation effect (seeing 357 pages of < < Chinese crude drug voluminous dictionary > >);
cortex Moutan, for ranunculaceae peony ( paeonia suffruticosa) root bark, acrid in the mouth is bitter, cool in nature, can heat clearing away, removing heat from blood, and blood, repercussive (seeing 1127 pages of < < Chinese medicine voluminous dictionary > >);
herba Pileae Scriptae, i.e. Herba Pileae Scriptae, for Chloranthaceae plant chu lan tree ( sarcaandra glabra) branch and leaf, acrid in the mouth, property is flat, can anti-inflammation, expelling wind and removing dampness, promoting blood circulation and stopping pain (seeing 42 pages of < < Chinese crude drug voluminous dictionary > >);
semen Coiciswei He Ordering-the section plant Semen Coicis ( coix lachrymal-jobi) kernel, slightly sweet flavor, cool in nature, have spleen invigorating, tonifying the lung, heat clearing away, dampness removing effect (seeing 2645 pages of < < Chinese crude drug voluminous dictionary > >);
herba Asarifor aristolochiaceae plant Herba Asari ( asarum sieboldii) whole herb with root, acrid in the mouth, warm in nature, can dispel the wind, cold expelling, Hang Shui, have one's ideas straightened out (seeing 1477 pages of < < Chinese medicine voluminous dictionary > >);
Radix Alangii, for Alangiaceae plant Radix Alangii ( alangium chinese) root or root bark, acrid in the mouth, warm in nature, poisonous, can dispelling wind and removing obstruction in the collateral, dissipating blood stasis analgesia, and have anesthesia and relaxed muscle effect (seeing 24 pages of < < Chinese medicine voluminous dictionary > >).
Above-mentioned medical material should meet the regulation under each medical material item in one of < < Chinese Pharmacopoeia > > version in 2010.
The preparation method of the pharmaceutical composition of the treatment hyperosteogeny that inventor provides is: 14 taste medical materials cleaned respectively, and with hot-air seasoning, broken in bulk; Use again disinfection by ultraviolet light, after mixing by formula proportion, put into container, add Chinese liquor to soak and process; Fire drying in using afterwards, pulverizes, grinds to form 60 order powder, and mix homogeneously obtains powder; Or pharmaceutical technology is pressed into pill routinely, every ball 1g; Or pharmaceutical technology incapsulates routinely, every 1g.
The pharmaceutical composition using method for the treatment of hyperosteogeny of the present invention is oral, warm water delivery service, every day 2 times, sooner or later each 1 5g.
Pharmaceutical composition of the present invention is used for the treatment of hyperosteogeny, has accepted patient's hundreds of people for medical treatment, cure rate 95%.Model case has:
Case one: Lee, female, 46 years old, lives Bijie City, Guizhou Province seven-star and close pear tree town, district.In July, 2010, patient feels the double-legged gonalgia unbearably.Seek medical advice, go hospital's X-ray film making, be diagnosed as hyperosteogeny, take this medicine 10 days, pain relief, continues to take disappearance in 10 days.The X-ray film making of 45Tian Houqu hospital, makes a definite diagnosis bony spur calcification; After half a year, follow up a case by regular visits to, not recurrence.
Case two: hole, man, 38 years old, lives Bijie City, Guizhou Province seven-star and close little Ji town, district.Patient's readme, from January, 2011, neck-shoulder pain, both hands are numb.Seek medical advice, hospital diagnosis is hyperosteogeny of cervical vertebra.Once took Chinese medicine and western medicine, poor effect, takes medicine of the present invention 10 days through changing, and pain relief continues to take 10 days pains and disappears; Serve on two months, recovery from illness.
Case three: Shen, man, 46 years old, lives in Bijie City, Guizhou Province seven-star Guan Qu Shen Jiawan.Patient feels ancon pain in April, 2010, dare not bend and stretch, and Qu Mou city hospital diagnosis is elbow joint matter hypertrophy.After medical, take medicine of the present invention 10 days, successful, pain relief; Serve on one month, all diseases disappear.Follow up a case by regular visits to half a year, not recurrence.
Case four: Zhang, man, 55 years old, lives in Wuhan City and build X office.In July, 2010, patient feels flank pain, when walking for very.Go certain urgent disorder in orthopaedics hospital X-ray film making, be diagnosed as lumbar vertebra hyperosteogeny.Once medication outer putting on the skin for oral administration, poor effect, takes medicine of the present invention 10 days through changing, and pain relief, continues to take 45 days, and pain disappears, and hospital's X-ray film making is gone in recovery from illness, makes a definite diagnosis bony spur calcification.
The pharmaceutical composition for the treatment of hyperosteogeny of the present invention has the following advantages: medicine source is wide, cost is low, instant effect, and curative effect is obvious especially, and various crowds are all had to expelling wind and removing dampness, promoting blood circulation and stopping pain, strong muscle dredging collateral effect, is applicable to treat the patient of bone matrix hyperplasia.
The specific embodiment
embodiment1 prepares the pharmaceutical composition for the treatment of hyperosteogeny according to the following step:
Get Olibanum 35g, Myrrha 20g, Radix Notoginseng 10g, Herba Taxilli 15g, Radix Achyranthis Bidentatae 15g, Rhizoma Chuanxiong 15g, Radix Dipsaci 15g, Radix Rehmanniae 15g, Caulis Akebiae 30g, Cortex Moutan 15g, Herba Pileae Scriptae 25g, Semen Coicis 20g, Herba Asari 3g, Radix Alangii 2g.14 taste medical materials are cleaned respectively, with hot-air seasoning, broken in bulk; Use again disinfection by ultraviolet light, after mixing by formula proportion, put into container, add Chinese liquor to soak and process; Fire drying in using afterwards, pulverizes, grinds to form 60 order powder, and mix homogeneously obtains powder.
embodiment2 prepare the pharmaceutical composition for the treatment of hyperosteogeny according to the following step:
Pharmaceutical formulation, with embodiment 1, is cleaned 14 taste medical materials respectively, with hot-air seasoning, and broken in bulk; Use again disinfection by ultraviolet light, after mixing by formula proportion, put into container, add Chinese liquor to soak and process; Fire drying in using afterwards, pulverizes, grinds to form 60 order powder, mix homogeneously, and pharmaceutical technology is made pill routinely, every ball 1g.
embodiment3 prepare the pharmaceutical composition for the treatment of hyperosteogeny according to the following step:
Pharmaceutical formulation, with embodiment 1, is cleaned 14 taste medical materials respectively, with hot-air seasoning, and broken in bulk; Use again disinfection by ultraviolet light, after mixing by formula proportion, put into container, add Chinese liquor to soak and process; Fire drying in using afterwards, pulverizes, grinds to form 60 order powder, mix homogeneously, and pharmaceutical technology incapsulates routinely, every 1g.

Claims (2)

1. treat a pharmaceutical composition for bone matrix hyperplasia, it is characterized in that this pharmaceutical composition made by the medical material of following quality proportioning: Olibanum 35g, Myrrha 20g, Radix Notoginseng 10g, Herba Taxilli 15g, Radix Achyranthis Bidentatae 15g, Rhizoma Chuanxiong 15g, Radix Dipsaci 15g, Radix Rehmanniae 15g, Caulis Akebiae 30g, Cortex Moutan 15g, Herba Pileae Scriptae 25g, Semen Coicis 20g, Herba Asari 3g, Radix Alangii 2g.
2. the method for preparing medicine described in claim 1, is characterized in that 14 taste medical materials to clean respectively, with hot-air seasoning, and broken in bulk; Use again disinfection by ultraviolet light, after mixing by formula proportion, put into container, add Chinese liquor to soak and process; Fire drying in using afterwards, pulverizes, grinds to form 60 order powder, and mix homogeneously obtains powder; Or pharmaceutical technology is pressed into pill routinely, every ball 1g; Or pharmaceutical technology incapsulates routinely, every 1g.
CN201410363657.4A 2014-07-29 2014-07-29 Medicine composition for treating osteoproliferation Pending CN104069394A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101664523A (en) * 2008-09-01 2010-03-10 陈群 Chinese medicinal composition for treating lumbar vertebrae bone hyperplasia
CN102125672A (en) * 2010-01-12 2011-07-20 姚玉健 Traditional Chinese medicine for treating cervical and lumbar spinal diseases and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101664523A (en) * 2008-09-01 2010-03-10 陈群 Chinese medicinal composition for treating lumbar vertebrae bone hyperplasia
CN102125672A (en) * 2010-01-12 2011-07-20 姚玉健 Traditional Chinese medicine for treating cervical and lumbar spinal diseases and preparation method thereof

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