CN104042892A - Traditional Chinese medicine (TCM) granule for treating postnatal constipation and preparation method thereof - Google Patents
Traditional Chinese medicine (TCM) granule for treating postnatal constipation and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine (TCM) granule for treating postnatal constipation, belonging to the field of TCMs. The granule is prepared from the following main raw materials in parts by weight: 10-15 parts of radix bupleuri, 4-9 parts of Chinese angelica, 10-30 parts of barbary wolfberry fruit, 6-15 parts of fleeceflower root, 10-20 parts of prepared rhizome of rehmannia, 5-15 parts of desertliving cistanche, 5-15 parts of motherwort herb, 1-9 parts of almonds, 1-9 parts of hemp seed, 10-30 parts of Chinese dates, 5-15 parts of Chinese arborvitae kernel, 10-35 parts of banana chips and 10-25 parts of dwarf lilyturf tuber. The granule has the characteristics of easiness in operation, obvious curative effects and no side effects, can also improve the internal immune functions of human bodies, enhance the disease resistance of bodies and improve blood circulation of tissues of visceral organs near colons, and has the function of relaxing bowels without impairing body fluid and the function of regulating qi and the middle warmer.
Description
Technical field
The invention discloses a kind of Chinese medicine granules, especially treat Chinese medicine granules of puerperal constipation and preparation method thereof.The invention belongs to Chinese medicine field.
Background technology
Puerpera's diet in puerperal is as usual, but stool a few days dry pain during not all right or defecation is difficult to the person of solving, and is called puerperal constipation, or claims difficulty in defecation after delivery, is one of modal puerperal disease.
The cause of disease that primary disease produces is mainly thin fluid injury in puerperal, and intestinal loses profit; Or the element official report deficiency of vital energy, because producing yang-energy, more hindering, the unable propelling movement stool of the deficiency of vital energy, in constipation intestinal, stops up under stagnant difficulty.According to its clinical manifestation, can be divided into blood deficiency dryness of the intestine, hyperactivity of fire caused by deficiency of YIN, deficient qi and blood three types.Therefore, food therapy focuses on the yin nourishing of enriching blood, loosening bowel to relieve constipation.Blood deficiency dryness of the intestine, puerperal, constipation with dry stool, number were not understood, or while separating under hard puckery difficulty, but diet is normal, and abdomen is without distending pain, shallow complexion, tongue is talked thin fur, and deficient pulse is puckery.Hyperactivity of fire caused by deficiency of YIN, puerperal constipation with dry stool, a few days is not understood, or while separating under hard puckery difficulty, abdominal distention distending pain, feverish sensation in the palms and soles, restlessness and thirst, red tongue, yellow and thin fur, thready and rapid pulse.QI and blood deficiency, difficulty in defecation, companion's asthma spontaneous perspiration, has a dizzy spell, mental weariness, pale tongue, large and weak pulse.
The reason of puerperal constipation has following 4 kinds of situations: 1, due to puerperal gastrointestinal function weaken, enterokinesia is slow, intestinal contents is long in the enteral time of staying, makes moisture absorption cause constipation with dry stool.2, through pregnant abdominal part excessive expansion, make abdominal muscles and pelvic floor tissue lax, defecation strength weakens.3, the weak defecation strength of human body in puerperal weakens.So often there is constipation phenomenon puerperal.4, dietary structure is unreasonable, and vegetable, fruit eat like a bird.
Causing the reason of puerperal constipation, is mainly that gastrointestinal function lowers, and wriggles slowly, and intestinal contents overstays, and moisture is by taken in excess.Next is phenolics, the muscular contraction force quantity not sufficient of stomach wall and pelvic floor.The 3rd, to give a birth late period, the damage more or less of perineum and pelvis, by neural reflex, restrains defecation action.The 4th, puerperal, diet was too particular about so-called high nutrition, lacked cellulose, and food debris reduces.The 5th, out-of-bed activity inconvenience, many puerperas are the uncomfortable bedpan defecation of using in bed again.
The side effect of puerperal constipation: 1 for the women that likes to be beautiful, it is very fearful suffering from constipation disease, because it can affect beauty treatment, brings toxin to patient's health, also have acne etc. the appearance of disease.When 2 constipation occur, some toxin can make large intestine swelling, so patient's lower part of the body blood circulation slows down, and affects the attractive in appearance of patient's configuration.3, may there is the situation of body odor in addition in patient, is sometimes local body odor, and halitosis be exactly wherein a kind of.The dysmenorrhea that 4, may cause in addition, work and life that patient cannot be felt at ease.
Granted publication CN102178769A(application number 201110111122.4) Chinese patent literature provides the pharmaceutical composition of a kind of prevention or treatment puerpera puerperal constipation, consists of: Radix Et Rhizoma Rhei 8-10 part, Fructus Cannabis 15-18 part, Radix Glycyrrhizae 10-15 part, Pericarpium Citri Reticulatae 20-25 part the active component of following weight portion.Application publication number CN102698045A(application number 201210205992.2) Chinese patent literature provides a kind of Chinese medicine preparation for the treatment of puerperal constipation: it is to be made by the raw material of Chinese medicine of following weight proportion: Radix Angelicae Sinensis 75-250g, Fructus Cannabis 100-250g, Radix Rehmanniae 100-250g, Aloe 30-100g, Herba Leonuri 50-250g and Mel 50-250g.
When the symptom for puerperal constipation, also there are some problems in prior art scheme: clinically to treatment constipation with dry stool in puerperal, and oliguria with reddish urine, flushing vexed, or have fever of the body, and xerostomia halitosis, abdominal distention or pain, red tongue with yellow fur or yellow dry curative effect are also undesirable.
Summary of the invention
Present situation for existing treatment puerperal constipation deficiency, one of object of the present invention is to provide a kind of Chinese medicine granules for the treatment of puerperal constipation, there is feature easy to operate, evident in efficacy and that have no side effect, can also improve inside of human body immunologic function, the resistance against diseases of enhancing body, improves the circulation of colon adjacent organ tissue blood, obtains the effect of loosening bowel to relieve constipation, relieving constipation is impairment of body fluid not, regulating the flow of Qi and the middle Jiao.To internals such as the heart, liver, spleen, lung, kidney, stomach, intestinal, to the effect of nontoxic, the secondary property of body, treatment puerperal constipation is had to certain curative effect.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
Treat a Chinese medicine granules for puerperal constipation, take off the primary raw material of stating weight proportion and be prepared from: Radix Bupleuri 10-15 part, Radix Angelicae Sinensis 4-9 part, Fructus Lycii 10-30 part, Radix Polygoni Multiflori 6-15 part, Radix Rehmanniae Preparata 10-20 part, Herba Cistanches 5-15 part, Herba Leonuri 5-15 part, Semen Armeniacae Amarum 1-9 part, Fructus Cannabis 1-9 part, Fructus Jujubae 10-30 part, Semen Platycladi 5-15 part, banana chip 10-35 part, Radix Ophiopogonis 10-25 part.
Treat a Chinese medicine granules for puerperal constipation, preferred scheme is, takes off the primary raw material of stating weight proportion and is prepared from: Radix Bupleuri 12-14 part, Radix Angelicae Sinensis 5-8 part, Fructus Lycii 15-25 part, Radix Polygoni Multiflori 8-13 part, Radix Rehmanniae Preparata 13-17 part, Herba Cistanches 8-13 part, Herba Leonuri 8-13 part, Semen Armeniacae Amarum 3-7 part, Fructus Cannabis 3-7 part, Fructus Jujubae 15-25 part, Semen Platycladi 8-13 part, banana chip 18-28 part, Radix Ophiopogonis 18-23 part.
Treat a Chinese medicine granules for puerperal constipation, better preferred scheme is, takes off the primary raw material of stating weight proportion and is prepared from: 13 parts of Radix Bupleuri, 6 parts of Radix Angelicae Sinensis, 20 parts of Fructus Lycii, 10 parts of Radix Polygoni Multiflori, 15 parts of Radix Rehmanniae Preparata, 10 parts of Herba Cistanches, 10 parts of Herba Leonuris, 5 parts, Semen Armeniacae Amarum, 5 parts of Fructus Cannabiss, 20 parts, Fructus Jujubae, 10 parts of Semen Platycladi, 25 parts of banana chips, 20 parts of Radix Ophiopogonis.
The preparation method of the Chinese medicine granules of above-mentioned treatment puerperal constipation, preferred scheme is that step is as follows:
(1) Radix Bupleuri is put into white vinegar and soak 1-5 days, taking-up is dried stand-by;
(2) by gained Radix Bupleuri (processed with vinegar) in step (1) with are ground into Radix Angelicae Sinensis, Radix Polygoni Multiflori, Radix Rehmanniae Preparata, Herba Cistanches, Herba Leonuri, Fructus Cannabis, banana chip and Radix Ophiopogonis smalls, mistake 120-140 mesh sieve;
(3) Fructus Lycii, Semen Armeniacae Amarum, Fructus Jujubae and Semen Platycladi are soaked 2 hours by the warm water that temperature is 20-40 ℃, water consumption is Fructus Lycii, Semen Armeniacae Amarum, Fructus Jujubae and Semen Platycladi gross weight 2-5 times;
(4) step (3) gained mixed liquor is heated to boiling, continues to filter after 1 hour, gained concentrating filter liquor to 1/2 of original volume is obtained to concentrated solution;
(5) gained smalls in step (2) is poured in the concentrated solution of step (4) gained, fully stirred into thick paste; Thick paste being dried to 1-2 hour, obtain oven dry thing, is that 70-90 ℃ (preferred 75-85 ℃, better preferably 80 ℃) are lower dry in temperature;
(6) step (5) gains are pressed into granule according to the preparation for processing of Chinese medicine granules.
Above-mentioned preparation method, preferred scheme is that step (1) is put into white vinegar and soaked 2-4 days (preferably 3 days).
Above-mentioned preparation method, preferred scheme is that step (2) is crossed 125-135 mesh sieve (preferably 130 mesh sieves).
Above-mentioned preparation method, preferred scheme is that step (3) is soaked (preferably 30 ℃) by the warm water that temperature is 25-35 ℃.
Above-mentioned preparation method, preferred scheme is that step (3) water consumption is 3-4 times (preferably 3.5 times) of Fructus Lycii, Semen Armeniacae Amarum, Fructus Jujubae and Semen Platycladi gross weight.
Above-mentioned preparation method, preferred scheme is that step (5) is dried 1.3-1.8 hour (preferably 1.5 hours) by thick paste.
Application when the present invention also provides medicine in preparation treatment stagnation of QI constipation in puerperal, puerperal blood deficiency and constipation, puerperal insufficiency of kidney-YANG constipation of described Chinese medicine composition.
Using method: for making the present invention reach optimum therapeuticing effect, while taking, get Chinese medicine granules of the present invention and put into cup, by warm water, wash open, get 8 grams at every turn, 3 times on the one, half an hour ante cibum morning, noon and afternoon, take, within 10 days, be a course for the treatment of.
Treat a Chinese medicine granules for puerperal constipation, the pharmacological effect of each crude drug is respectively:
Radix Bupleuri: bitter in the mouth, cold nature.Return liver, gallbladder meridian.Processed with vinegar can relax and rise loose property, strengthens dispersing the depressed liver-QI for alleviating pain effect, is applicable to hypochondriac pain, stomachache and the menoxenia of stagnation of QI due to depression of the liver.Normal and Fructus Aurantii, Rhizoma Cyperi, Rhizoma Chuanxiong are equal to use.
Radix Angelicae Sinensis: sweet in the mouth; Pungent; Bitter; Warm in naturely return liver; The heart; Spleen channel.The all cards of blood deficiency; Menoxenia; Amenorrhea; Dysmenorrhea; Lump in the abdomen knot is poly-; Metrorrhagia; Asthenia cold abdominalgia; Flaccidity syndrome and arthralgia syndrome; Numbness of the skin; Dryness of the intestine dyschezia; Heavy after bloody dysentery; Ulcer sores; Injury from falling down.
Fructus Lycii: nature and flavor: sweet, flat.Gui Jing: return liver, kidney channel.Effect: nourishing the liver and kidney, replenishing vital essence to improve eyesight.Cure mainly: for asthenia damage of essence.Doctor's knee joint soreness, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, blurred vision is not clear.
Radix Polygoni Multiflori: nature and flavor: bitter, sweet, puckery. temperature.Gui Jing: return liver, the heart, kidney channel.Effect: removing toxic substances, disappear de-, loosening bowel to relieve constipation.Cure mainly: for scrofula carbuncle sore, rubella pruritus, dryness of the intestine constipation; Hyperlipidemia.
Herba Leonuri: nature and flavor: bitter, pungent, be slightly cold.Gui Jing: return liver, pericardium channel.Effect: promoting blood flow to regulate menstruation, inducing diuresis to remove edema.Cure mainly: for menoxenia, dysmenorrhea, amenorrhea, lochiorrhea, edema oliguria; Acute nephritis edema.
Radix Rehmanniae Preparata: nature and flavor: sweet, tepor.Gui Jing: return liver, kidney channel.Effect: nourishing YIN and supplementing blood, beneficial essence is filled out marrow.Cure mainly: for the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, night sweat seminal emission, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, severe palpitation, menoxenia, metrostaxis, dizzy, tinnitus, early whitening of beard and hair.
Herba Cistanches: bitter, pungent, tepor.GUIXIN, kidney, lung meridian.The Fructus Alpiniae Oxyphyllae of calming the nerves, eliminates the phlegm, detumescence insomnia and dreamful sleep, forgetful palpitation with fear, staring spells.Insomnia and dreamful sleep, severe palpitation, forgetful.Epilepsy mania and irritation, spasm is twitched, skin sore.
Semen Armeniacae Amarum: another name: Semen Armeniacae Amarum, nature and flavor: hardship, tepor; Slightly poisonous.Gui Jing: return lung, large intestine channel.Effect: sending down the abnormal ascending QI relieving cough and asthma, loosening bowel to relieve constipation.Curing mainly: for cough and asthma. fullness in the chest abundant expectoration, blood deficiency Tianjin is withered, dryness of the intestine constipation.
Fructus Cannabis: matter profit is logical falls; There is the laxation of moisturizing, relieving stranguria by diuresis, the effect of promoting blood circulation by removing wind; Cure mainly dryness of the intestine constipation, edema, beriberi, pyretic stranguria, skin migratory arthralgia, menoxenia, skin ulcer tinea, erysipelas.
Fructus Jujubae: nature and flavor: sweet, temperature.Gui Jing: return spleen, stomach warp.Effect: invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind.Cure mainly: for the empty lack of appetite of board. weak loose stool, woman hysteria.
Semen Platycladi: nature and flavor: sweet, flat.Gui Jing: GUIXIN, kidney, large intestine channel.Effect: tranquilizing by nourishing the heart, hidroschesis, intestine moistening.Cure mainly: for fidgets due to deficiency insomnia, severe palpitation, night sweat due to yin deficiency, dryness of the intestine constipation.
Banana chip: promoting the production of body fluid to quench thirst, nourishing the lung to loosen bowels, the low absorption easy to digest of heat, has antiobesity action, promotes enterokinesia, and relieving constipation, has the effect reducing blood pressure.
Radix Ophiopogonis: nature and flavor: sweet, micro-hardship, is slightly cold.Gui Jing: GUIXIN, lung, stomach warp.Effect: YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.Cure mainly: for dryness of the lung dry cough.Chronic consumptive disease cough, Tianjin wound is thirsty, vexed insomnia, interior-heat is quenched one's thirst, dryness of the intestine constipation; Pharyngeal diphtheria.
The principle of Chinese medicine granules of the present invention based on traditional Chinese medical herbal treatment puerperal constipation.The Chinese medicinal material of selecting all has blood enriching and dryness moistening, benefiting QI and nourishing blood and relieving constipation effect, and cheap, and life-time service also can not cause patient's financial burden, is the comparatively desirable medicine for the treatment of puerperal constipation.
Compared with prior art, technical advantage of the present invention is embodied in:
1, the present invention's medical material used can not cause damage for the health mechanism of sufferer, and audient crowd is wide, is applicable to child and old people and takes.
2, medical material cost used in the present invention is relatively cheap, and compared with prior art the bright prepared Chinese medicine granules cost of this law is more reasonable.
3, therapeutic effect of the present invention is than prior art, and therapeutic effect is more obvious, and treatment cycle is short, there is no obvious sequela, can long-term taking.
The specific embodiment
Below in conjunction with embodiment and experimental example, describe technical scheme of the present invention in detail, but protection domain is not by this restriction.
embodiment 1treat a Chinese medicine granules for puerperal constipation, take off the primary raw material of stating weight proportion (every part of 10g) and be prepared from: 10 parts of Radix Bupleuri, 4 parts of Radix Angelicae Sinensis, 10 parts of Fructus Lycii, 6 parts of Radix Polygoni Multiflori, 10 parts, Radix Rehmanniae Preparata, 5 parts of Herba Cistanches, 5 parts of Herba Leonuris, 1 part, Semen Armeniacae Amarum, 1 part of Fructus Cannabis, 10 parts, Fructus Jujubae, 5 parts of Semen Platycladi, 10 parts of banana chips, 10 parts of Radix Ophiopogonis.
The preparation process of above-mentioned Chinese medicine granules is as follows:
(1) Radix Bupleuri is put into white vinegar and soaked 1 day, taking-up is dried stand-by;
(2) by gained Radix Bupleuri (processed with vinegar) in step (1) with are ground into Radix Angelicae Sinensis, Radix Polygoni Multiflori, Radix Rehmanniae Preparata, Herba Cistanches, Herba Leonuri, Fructus Cannabis, banana chip and Radix Ophiopogonis smalls, mistake 120 mesh sieves;
(3) Fructus Lycii, Semen Armeniacae Amarum, Fructus Jujubae and Semen Platycladi are soaked 2 hours by the warm water that temperature is 20 ℃, water consumption is Fructus Lycii, Semen Armeniacae Amarum, Fructus Jujubae and Semen Platycladi gross weight 2 times;
(4) step (3) gained mixed liquor is heated to boiling, continues to filter after 1 hour, gained concentrating filter liquor to 1/2 of original volume is obtained to concentrated solution;
(5) gained smalls in step (2) is poured in the concentrated solution of step (4) gained, fully stirred into thick paste; Thick paste being dried to 1-2 hour, obtain oven dry thing, is dry at 70 ℃ in temperature;
(6) step (5) gains are pressed into granule according to the preparation for processing of Chinese medicine granules.
typical case oneking XX, women, patient 28 years old, the sewing worker of factory.In JIUYUE, 2008 childbirth, has given a birth and had examined afterwards: tool husband patient has told about and produced under rear constipation with dry stool difficulty since wife, 4-6 day a line, also slightly with slight anemia, neurolysis, takes enema defaecation, but originally effect feels not too effective well recently.The symptoms such as xerostomia, shallow complexion are simple and unadorned, two cheek black speck within recent several days, have also been there is.From friend's mouth, learn Chinese medicine granules of the present invention, just bought 4 courses for the treatment of and taken.
Take embodiment 1 gained Chinese medicine granules 7 days, weak, the symptom of xerostomia alleviates, and relieving constipation is substantially smooth and easy, uses 1 month, and malaise symptoms disappears completely; After recovering, consolidate and use 10 days again, drug withdrawal is so far without recurrence.
embodiment 2treat a Chinese medicine granules for puerperal constipation, take off the primary raw material of stating weight proportion (getting 20g for every part) and be prepared from: 15 parts of Radix Bupleuri, 9 parts of Radix Angelicae Sinensis, 30 parts of Fructus Lycii, 15 parts of Radix Polygoni Multiflori, 20 parts, Radix Rehmanniae Preparata, 15 parts of Herba Cistanches, 15 parts of Herba Leonuris, 9 parts, Semen Armeniacae Amarum, 9 parts of Fructus Cannabiss, 30 parts, Fructus Jujubae, 15 parts of Semen Platycladi, 35 parts of banana chips, 25 parts of Radix Ophiopogonis.
The preparation process of above-mentioned Chinese medicine granules is as follows:
(1) Radix Bupleuri is put into white vinegar and soaked 5 days, taking-up is dried stand-by;
(2) by gained Radix Bupleuri (processed with vinegar) in step (1) with are ground into Radix Angelicae Sinensis, Radix Polygoni Multiflori, Radix Rehmanniae Preparata, Herba Cistanches, Herba Leonuri, Fructus Cannabis, banana chip and Radix Ophiopogonis smalls, mistake 140 mesh sieves;
(3) Fructus Lycii, Semen Armeniacae Amarum, Fructus Jujubae and Semen Platycladi are soaked 2 hours by the warm water that temperature is 40 ℃, water consumption is Fructus Lycii, Semen Armeniacae Amarum, Fructus Jujubae and Semen Platycladi gross weight 5 times;
(4) step (3) gained mixed liquor is heated to boiling, continues to filter after 1 hour, gained concentrating filter liquor to 1/2 of original volume is obtained to concentrated solution;
(5) gained smalls in step (2) is poured in the concentrated solution of step (4) gained, fully stirred into thick paste; Thick paste being dried to 1-2 hour, obtain oven dry thing, is dry at 90 ℃ in temperature;
(6) step (5) gains are pressed into granule according to the preparation for processing of Chinese medicine granules.
typical case twowoods XX, female, 25 years old, Mouping District, Yantai City, certain co-director.Patient's readme: since in December, 2011 divides just constipation always of puerperium, within latter 3 months, just go out to have come to work adding to have given a birth, operating pressure is larger, long-term in nervous working environment, has had the time defecation of half a year to have some setbacks, endocrine is seriously lacked of proper care, cause small pox on the face a lot, and melanin deposition, skin is intense darkness without light, going to see the doctor, to be diagnosed as be puerperal constipation, and doctor advised adopts Chinese medicinal granule conditioning of the present invention.
Take 1 course for the treatment of of the embodiment of the present invention 2 gained Chinese medicinal granule, stool is adjusted, and foul smell is fallen, and black speck color shoals naturally on the face.Continue to take 1 course for the treatment of of embodiment 2 gained Chinese medicinal granule, all diseases disappear substantially.The a line on the one of defecating, just matter is dry not rare, and skin gloss is flexible.
embodiment 3treat a Chinese medicine granules for puerperal constipation, take off the primary raw material of stating weight proportion (getting 30g for every part) and be prepared from: 12 parts of Radix Bupleuri, 5 parts of Radix Angelicae Sinensis, 15 parts of Fructus Lycii, 8 parts of Radix Polygoni Multiflori, 13 parts, Radix Rehmanniae Preparata, 8 parts of Herba Cistanches, 8 parts of Herba Leonuris, 3 parts, Semen Armeniacae Amarum, 3 parts of Fructus Cannabiss, 15 parts, Fructus Jujubae, 8 parts of Semen Platycladi, 18 parts of banana chips, 18 parts of Radix Ophiopogonis.
The preparation process of above-mentioned Chinese medicine granules is as follows:
(1) Radix Bupleuri is put into white vinegar and soaked 2 days, taking-up is dried stand-by;
(2) by gained Radix Bupleuri (processed with vinegar) in step (1) with are ground into Radix Angelicae Sinensis, Radix Polygoni Multiflori, Radix Rehmanniae Preparata, Herba Cistanches, Herba Leonuri, Fructus Cannabis, banana chip and Radix Ophiopogonis smalls, mistake 125 mesh sieves;
(3) Fructus Lycii, Semen Armeniacae Amarum, Fructus Jujubae and Semen Platycladi are soaked 2 hours by the warm water that temperature is 25 ℃, water consumption is Fructus Lycii, Semen Armeniacae Amarum, Fructus Jujubae and Semen Platycladi gross weight 3 times;
(4) step (3) gained mixed liquor is heated to boiling, continues to filter after 1 hour, gained concentrating filter liquor to 1/2 of original volume is obtained to concentrated solution;
(5) gained smalls in step (2) is poured in the concentrated solution of step (4) gained, fully stirred into thick paste; Thick paste being dried 1.3 hours, obtain oven dry thing, is dry at 75 ℃ in temperature;
(6) step (5) gains are pressed into granule according to the preparation for processing of Chinese medicine granules.
embodiment 4treat a Chinese medicine granules for puerperal constipation, take off the primary raw material of stating weight proportion (getting 40g for every part) and be prepared from: 14 parts of Radix Bupleuri, 8 parts of Radix Angelicae Sinensis, 25 parts of Fructus Lycii, 13 parts of Radix Polygoni Multiflori, 17 parts, Radix Rehmanniae Preparata, 13 parts of Herba Cistanches, 13 parts of Herba Leonuris, 7 parts, Semen Armeniacae Amarum, 7 parts of Fructus Cannabiss, 25 parts, Fructus Jujubae, 13 parts of Semen Platycladi, 28 parts of banana chips, 23 parts of Radix Ophiopogonis.
The preparation process of above-mentioned Chinese medicine granules is as follows:
(1) Radix Bupleuri is put into white vinegar and soaked 4 days, taking-up is dried stand-by;
(2) by gained Radix Bupleuri (processed with vinegar) in step (1) with are ground into Radix Angelicae Sinensis, Radix Polygoni Multiflori, Radix Rehmanniae Preparata, Herba Cistanches, Herba Leonuri, Fructus Cannabis, banana chip and Radix Ophiopogonis smalls, mistake 135 mesh sieves;
(3) Fructus Lycii, Semen Armeniacae Amarum, Fructus Jujubae and Semen Platycladi are soaked 2 hours by the warm water that temperature is 35 ℃, water consumption is Fructus Lycii, Semen Armeniacae Amarum, Fructus Jujubae and Semen Platycladi gross weight 4 times;
(4) step (3) gained mixed liquor is heated to boiling, continues to filter after 1 hour, gained concentrating filter liquor to 1/2 of original volume is obtained to concentrated solution;
(5) gained smalls in step (2) is poured in the concentrated solution of step (4) gained, fully stirred into thick paste; Thick paste being dried 1.8 hours, obtain oven dry thing, is dry at 85 ℃ in temperature;
(6) step (5) gains are pressed into granule according to the preparation for processing of Chinese medicine granules.
typical case four:in XX, Heze City, Shandong Province people, female, 28 years old, peasant, patient's readme is from having given a birth in time of 1 month, and stool has some setbacks always, sometimes within one week, just the last time defecates, at every turn all very painful, nearest sensation is more and more come more serious, and husband is just with patient to do comprehensive inspection to hospital, due to the constipation that the breakage of childbirth vigour causes, Chinese medicine granules of the present invention is taken in old docter of TCM's suggestion.So just bought 3 courses for the treatment of.
Use the present embodiment 4 gained Chinese medicine granules after 5 days, patient has just felt QI and blood smoothness, defecate smooth and easy, see that the patient that take a favorable turn has bought again 2 courses for the treatment of, continue to use after 2 courses for the treatment of patient's symptom that does not feel like oneself to disappear completely, mood has also and then improved, and it is more healthy that health also becomes, and it is normal that endocrine has also been recovered.Continue to have used 1 course for the treatment of as consolidation, nothing recurrence after drug withdrawal.
embodiment 5treat a Chinese medicine granules for puerperal constipation, take off the primary raw material of stating weight proportion (getting 50g for every part) and be prepared from: 13 parts of Radix Bupleuri, 6 parts of Radix Angelicae Sinensis, 20 parts of Fructus Lycii, 10 parts of Radix Polygoni Multiflori, 15 parts, Radix Rehmanniae Preparata, 10 parts of Herba Cistanches, 10 parts of Herba Leonuris, 5 parts, Semen Armeniacae Amarum, 5 parts of Fructus Cannabiss, 20 parts, Fructus Jujubae, 10 parts of Semen Platycladi, 25 parts of banana chips, 20 parts of Radix Ophiopogonis.
The preparation process of above-mentioned Chinese medicine granules is as follows:
(1) Radix Bupleuri is put into white vinegar and soaked 3 days, taking-up is dried stand-by;
(2) by gained Radix Bupleuri (processed with vinegar) in step (1) with are ground into Radix Angelicae Sinensis, Radix Polygoni Multiflori, Radix Rehmanniae Preparata, Herba Cistanches, Herba Leonuri, Fructus Cannabis, banana chip and Radix Ophiopogonis smalls, mistake 130 mesh sieves;
(3) Fructus Lycii, Semen Armeniacae Amarum, Fructus Jujubae and Semen Platycladi are soaked 2 hours by the warm water that temperature is 30 ℃, water consumption is Fructus Lycii, Semen Armeniacae Amarum, Fructus Jujubae and Semen Platycladi gross weight 3.5 times;
(4) step (3) gained mixed liquor is heated to boiling, continues to filter after 1 hour, gained concentrating filter liquor to 1/2 of original volume is obtained to concentrated solution;
(5) gained smalls in step (2) is poured in the concentrated solution of step (4) gained, fully stirred into thick paste; Thick paste being dried 1.5 hours, obtain oven dry thing, is dry at 80 ℃ in temperature;
(6) step (5) gains are pressed into granule according to the preparation for processing of Chinese medicine granules.
test example 1the clinical practice of the Chinese medicine granules water preparation of embodiment 5 gained treatments puerperal constipations: in June, 2008-2013 year June, screen 100 routine patients, oldest 35 years old, minimal ages 20 years old, 27 years old mean age in 4 hospitals.Test 1 week before, carries out Continuous Observation to this crowd, records symptom and variation, be divided at random two groups, experimental group and matched group, experimental group is taken embodiment 5 products obtained therefroms, and matched group is taken other medicine (the conventional medicine such as osmotic laxative, irritant laxative, emollient laxative).Using method is: while taking, gets Chinese medicine granules of the present invention and puts into cup, by warm water, wash open, get 8 grams at every turn, and 3 times on the one, half an hour ante cibum morning, noon and afternoon, take, within 10 days, be a course for the treatment of.Curative effect situation criterion: cure: malaise symptoms disappears, and relieving constipation is smooth and easy; Effective: malaise symptoms alleviates or part disappears, and relieving constipation is substantially smooth and easy; Invalid: malaise symptoms is unchanged.Result is as shown in table 1.
Table 1: take embodiment 5 product 20-35 year puerperal constipation patient treatment results
Therapeutic effect: cure 70 examples (87.5%), effective 8 examples (10%), invalid 2 examples (2.5%), total effective rate 97.5%.Successful is better than matched group.
During taking, self-induction symptom and relieving constipation change as shown in table 2.
Table 2:
Treat a Chinese medicine granules for puerperal constipation, Herba Leonuri wherein, Radix Polygoni Multiflori, banana chip is combined and is done monarch, has attending effectiveness; Ministerial drug is Radix Bupleuri, Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Semen Platycladi, auxiliary treatment; Adjuvant drug is Herba Cistanches, Semen Armeniacae Amarum, Fructus Cannabis, Radix Ophiopogonis; Making medicine is Fructus Lycii and Fructus Jujubae.Monarch drug is being born attending effectiveness in the present invention; Ministerial drug is the medicine that auxiliary monarch drug is strengthened the main disease for the treatment of and main symptom; The double disease of adjuvant drug treatment, slows down the strong of monarch drug and ministerial drug; Fructus Lycii and Fructus Jujubae, as making medicine, play a part guiding drug.
Take Chinese medicine granules of the present invention 10 days, more than 53% feeling takes a turn for the better to some extent, and malaise symptoms improves; Take 20 days, more than 72% feeling takes a turn for the better to some extent, and malaise symptoms improves or disappears, and QI and blood is unobstructed; Take 30 days, more than 97% feeling takes a turn for the better to some extent, and malaise symptoms improves or disappears, and relieving constipation is smooth and easy, the recovery from illness of some patients were self-induction.In experimental group, take more than 30 days, effective percentage can reach 93%, and matched group is only 76%.
It should be pointed out that the specific embodiment is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clearly disclosed or according to undoubted the obtaining of the written description of file, all should think the claimed scope of this patent.
Claims (10)
1. a Chinese medicine granules for the treatment of puerperal constipation, is characterized in that: take off the primary raw material of stating weight proportion and be prepared from: Radix Bupleuri 10-15 part, Radix Angelicae Sinensis 4-9 part, Fructus Lycii 10-30 part, Radix Polygoni Multiflori 6-15 part, Radix Rehmanniae Preparata 10-20 part, Herba Cistanches 5-15 part, Herba Leonuri 5-15 part, Semen Armeniacae Amarum 1-9 part, Fructus Cannabis 1-9 part, Fructus Jujubae 10-30 part, Semen Platycladi 5-15 part, banana chip 10-35 part, Radix Ophiopogonis 10-25 part.
2. Chinese medicine granules according to claim 1, is characterized in that: take off the primary raw material of stating weight proportion and be prepared from: Radix Bupleuri 12-14 part, Radix Angelicae Sinensis 5-8 part, Fructus Lycii 15-25 part, Radix Polygoni Multiflori 8-13 part, Radix Rehmanniae Preparata 13-17 part, Herba Cistanches 8-13 part, Herba Leonuri 8-13 part, Semen Armeniacae Amarum 3-7 part, Fructus Cannabis 3-7 part, Fructus Jujubae 15-25 part, Semen Platycladi 8-13 part, banana chip 18-28 part, Radix Ophiopogonis 18-23 part.
3. Chinese medicine granules according to claim 1, is characterized in that: take off the primary raw material of stating weight proportion and be prepared from: 13 parts of Radix Bupleuri, 6 parts of Radix Angelicae Sinensis, 20 parts of Fructus Lycii, 10 parts of Radix Polygoni Multiflori, 15 parts, Radix Rehmanniae Preparata, 10 parts of Herba Cistanches, 10 parts of Herba Leonuris, 5 parts, Semen Armeniacae Amarum, 5 parts of Fructus Cannabiss, 20 parts, Fructus Jujubae, 10 parts of Semen Platycladi, 25 parts of banana chips, 20 parts of Radix Ophiopogonis.
4. according to the preparation method of the arbitrary described Chinese medicine granules of claim 1-3, it is characterized in that, step is as follows:
(1) Radix Bupleuri is put into white vinegar and soak 1-5 days, taking-up is dried stand-by;
(2) by gained Radix Bupleuri (processed with vinegar) in step (1) with are ground into Radix Angelicae Sinensis, Radix Polygoni Multiflori, Radix Rehmanniae Preparata, Herba Cistanches, Herba Leonuri, Fructus Cannabis, banana chip and Radix Ophiopogonis smalls, mistake 120-140 mesh sieve;
(3) Fructus Lycii, Semen Armeniacae Amarum, Fructus Jujubae and Semen Platycladi are soaked 2 hours by the warm water that temperature is 20-40 ℃, water consumption is Fructus Lycii, Semen Armeniacae Amarum, Fructus Jujubae and Semen Platycladi gross weight 2-5 times;
(4) step (3) gained mixed liquor is heated to boiling, continues to filter after 1 hour, gained concentrating filter liquor to 1/2 of original volume is obtained to concentrated solution;
(5) gained smalls in step (2) is poured in the concentrated solution of step (4) gained, fully stirred into thick paste; Thick paste being dried to 1-2 hour, obtain oven dry thing, is that 70-90 ℃ (preferred 75-85 ℃, better preferably 80 ℃) are lower dry in temperature;
(6) step (5) gains are pressed into granule according to the preparation for processing of Chinese medicine granules.
5. preparation method according to claim 4, is characterized in that, step (1) is put into white vinegar and soaked 2-4 days (preferably 3 days).
6. preparation method according to claim 4, is characterized in that, step (2) is crossed 125-135 mesh sieve (preferably 130 mesh sieves).
7. preparation method according to claim 4, is characterized in that, step (3) is soaked (preferably 30 ℃) by the warm water that temperature is 25-35 ℃.
8. preparation method according to claim 4, is characterized in that, step (3) water consumption is 3-4 times (preferably 3.5 times) of Fructus Lycii, Semen Armeniacae Amarum, Fructus Jujubae and Semen Platycladi gross weight.
9. preparation method according to claim 4, is characterized in that, step (5) is dried 1.3-1.8 hour (preferably 1.5 hours) by thick paste.
10. the application of the Chinese medicine composition unguentum as described in as arbitrary in claim 1-3 when the medicine of preparation treatment stagnation of QI constipation in puerperal, puerperal blood deficiency and constipation, insufficiency of kidney-YANG constipation in puerperal.
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