CN104031032B - 一种埃索美拉唑钠化合物及其药物组合物 - Google Patents
一种埃索美拉唑钠化合物及其药物组合物 Download PDFInfo
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- CN104031032B CN104031032B CN201410316155.6A CN201410316155A CN104031032B CN 104031032 B CN104031032 B CN 104031032B CN 201410316155 A CN201410316155 A CN 201410316155A CN 104031032 B CN104031032 B CN 104031032B
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- esomeprazole sodium
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Description
放样时间 | 外观 | 总杂% | 含量% |
0M | 白色粉末 | 0.08 | 99.9 |
1M | 白色粉末 | 0.11 | 99.9 |
2M | 白色粉末 | 0.14 | 99.9 |
3M | 白色粉末 | 0.16 | 99.8 |
6M | 类白色粉末 | 0.20 | 99.8 |
放样时间 | 外观 | 总杂% | 含量% |
0M | 白色粉末 | 0.08 | 99.9 |
3M | 白色粉末 | 0.11 | 99.9 |
6M | 白色粉末 | 0.16 | 99.8 |
9M | 白色粉末 | 0.21 | 99.8 |
12M | 白色粉末 | 0.24 | 99.8 |
Claims (11)
Priority Applications (1)
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CN201410316155.6A CN104031032B (zh) | 2014-07-04 | 2014-07-04 | 一种埃索美拉唑钠化合物及其药物组合物 |
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CN201410316155.6A CN104031032B (zh) | 2014-07-04 | 2014-07-04 | 一种埃索美拉唑钠化合物及其药物组合物 |
Publications (2)
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CN104031032A CN104031032A (zh) | 2014-09-10 |
CN104031032B true CN104031032B (zh) | 2016-04-27 |
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CN201410316155.6A Active CN104031032B (zh) | 2014-07-04 | 2014-07-04 | 一种埃索美拉唑钠化合物及其药物组合物 |
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Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN105669648A (zh) * | 2014-11-21 | 2016-06-15 | 北大方正集团有限公司 | 一种高纯度埃索美拉唑钠的制备方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
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KR20130038949A (ko) * | 2004-06-24 | 2013-04-18 | 아스트라제네카 아베 | 에소메프라졸 나트륨염의 제조에서 사용하기 위한 결정 변형의 제조를 위한 신규한 방법 |
US8063074B2 (en) * | 2006-05-04 | 2011-11-22 | Dr. Reddy's Laboratories Limited | Polymorphic forms of esomeprazole sodium |
CN102321071B (zh) * | 2011-07-20 | 2013-01-23 | 江苏奥赛康药业股份有限公司 | 一种高纯度埃索美拉唑钠的工业化生产方法 |
CN102746272B (zh) * | 2012-04-11 | 2014-06-25 | 江苏奥赛康药业股份有限公司 | 一种埃索美拉唑钠多晶型物及其制备方法和应用 |
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C06 | Publication | ||
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C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
EE01 | Entry into force of recordation of patent licensing contract |
Application publication date: 20140910 Assignee: Nanjing Hairun Pharmaceutical Co. Ltd. Assignor: Jiangsu Aosaikang Pharmaceutical Co., Ltd. Contract record no.: 2017320000132 Denomination of invention: Esomeprazole sodium compound and medicine composition thereof Granted publication date: 20160427 License type: Exclusive License Record date: 20170522 |
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EE01 | Entry into force of recordation of patent licensing contract | ||
CP01 | Change in the name or title of a patent holder |
Address after: 211112 Jiangsu Province, Nanjing City, Jiangning Science Park Road No. 699 Patentee after: Jiangsu Aosaikang Pharmaceutical Co., Ltd. Address before: 211112 Jiangsu Province, Nanjing City, Jiangning Science Park Road No. 699 Patentee before: Jiangsu Aosaikang Pharmaceutical Co., Ltd. |
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CP01 | Change in the name or title of a patent holder |