CN104027652A - Traditional Chinese medicine preparation for decreasing blood sugar and preparation method of traditional Chinese medicine preparation - Google Patents

Traditional Chinese medicine preparation for decreasing blood sugar and preparation method of traditional Chinese medicine preparation Download PDF

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CN104027652A
CN104027652A CN201410296400.1A CN201410296400A CN104027652A CN 104027652 A CN104027652 A CN 104027652A CN 201410296400 A CN201410296400 A CN 201410296400A CN 104027652 A CN104027652 A CN 104027652A
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radix
rhizoma
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田艺儿
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Shenzhen original pure grass Biotechnology Co., Ltd.
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Abstract

The invention discloses a traditional Chinese medicine preparation for decreasing blood sugar and a preparation method of the traditional Chinese medicine preparation. The preparation disclosed by the invention is a composition liquid preparation prepared from following raw materials: purified water, radix rehmanniae recen, root bark of white mulberry, cortex lycii radicis, corn stigma, radices trichosanthis, coptis chinensis, longspur epimedium, acanthopanax root, rhizoma polygonati, rhodiola rosea, gastrodia elata, fruit of Chinese wolfberry, ligusticum wallichii, rhizoma anemarrhenae, inula flower, ginseng, white sugar and 65% ethanol solution by the procedures of crushing, decocting, mixing, agitating and the like. The traditional Chinese medicine preparation is significant in blood sugar decreasing effect, free of toxic and side effects, stable in effect, and simple and feasible in preparation process.

Description

A kind of hypoglycemic Chinese medicine prepn and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine preparation of hypoglycemic activity, relate to specifically Chinese medicine preparation of this hypoglycemic activity and preparation method thereof.
Background technology
Sugar in blood of human body is called blood glucose, all glucose in most cases, sugar is one of requisite nutrition of human body, in human body, the energy major part of each histiocyte activity is from glucose, corn, vegetable etc. that people take in, be converted into glucose through digestive system and enter in blood, is transported to the cell of whole body, as the source of energy, so blood glucose must keep certain level just can maintain the needs of each Organ and tissue.Normal person is 4.1-6.0mmol/L in fasting glucose concentration, and fasting glucose concentration exceedes 6.0 mmol/L and is called hyperglycemia, at this time can some glucose along with urine is discharged, Here it is glycosuria.
Along with the progressively raising of people's living standard, the people who suffers from diabetes is more and more, diabetes are diseases of a kind of very difficult healing, needs of patients Long-term taking medicine and keeping on a diet, the performance such as the common manifestation of diabetes has polyuria, polydipsia, polyphagia, become thin, i.e. " three-many-one-little " symptom, and diabetes very easily cause the complication such as cardiovascular pathological changes, nephropathy, neuropathy.
At present, clinical hypoglycemic medicine used, only have the several drugses few in number such as insulin, and only have injection just effective, also there is no a kind of medicine that can cure diabetes completely, mainly with hypoglycemic medicine, also be regulating and controlling blood sugar, moreover these medicines all have some limitations and untoward reaction, may cause the side effect such as hypoglycemia, lactic acidosis.So, find a kind of safe, effective, hypoglycemic drug of having no side effect, become the task of top priority.
Summary of the invention
Object of the present invention is for above-mentioned deficiency, on the basis of secret prescription handed down in the family from generation to generation, in conjunction with modern Chinese and western medicine technology, the Chinese medicine preparation that a kind of prevention and reduction hyperglycemia are provided, is to provide this Chinese medicine preparation and preparation method thereof specifically, and blood sugar decreasing effect of the present invention is obvious, and nontoxic, have no side effect, effect stability, reparation technology is simple and easy to do.
Technical scheme of the present invention is as described below:
Preparation of the present invention is the compositions liquid formulation being prepared into by pure water, Radix Rehmanniae, Cortex Mori, Cortex Lycii, Stigma Maydis, Radix Trichosanthis, Rhizoma Coptidis, Herba Epimedii, Radix Et Caulis Acanthopanacis Senticosi, Rhizoma Polygonati, Radix Rhodiolae, Rhizoma Gastrodiae, Fructus Lycii, Rhizoma Chuanxiong, the Rhizoma Anemarrhenae, Flos Inulae, Radix Ginseng, white sugar and 65% alcoholic solution, and wherein the quality proportioning of each component is:
Pure water 4000-8000g Radix Rehmanniae 10-30g Cortex Mori 20-40g
Cortex Lycii 20-40g Stigma Maydis 25-35g Radix Trichosanthis 20-30g
Rhizoma Coptidis 15-25g Fructus Corni 20-30g Radix Et Caulis Acanthopanacis Senticosi 20-30g
Rhizoma Polygonati 20-30g Radix Rhodiolae 20-30g Rhizoma Gastrodiae 30-40g
Fructus Lycii 30-40g Rhizoma Chuanxiong 20-30g Rhizoma Anemarrhenae 20-30g
Flos Inulae 20-35g Radix Ginseng 10-20g white sugar 20-30g
65% alcoholic solution 15-30g.
In order to obtain better effect, the present invention preferably raw material mass mixture ratio is:
Pure water 5000-8000g Radix Rehmanniae 10-20g Cortex Mori 20-30g
Cortex Lycii 20-30g Stigma Maydis 25-30g Radix Trichosanthis 20-25g
Rhizoma Coptidis 15-20g Fructus Corni 20-25g Radix Et Caulis Acanthopanacis Senticosi 20-25g
Rhizoma Polygonati 20-25g Radix Rhodiolae 20-25g Rhizoma Gastrodiae 30-35g
Fructus Lycii 30-35g Rhizoma Chuanxiong 20-25g Rhizoma Anemarrhenae 20-25g
Flos Inulae 20-30g Radix Ginseng 10-20g white sugar 20-30g
65% alcoholic solution 15-25g.
Certainly, in order to obtain further good effect, the present invention also preferably raw material mass mixture ratio be:
Pure water 6000g Radix Rehmanniae 15g Cortex Mori 25g
Cortex Lycii 25g Stigma Maydis 25g Radix Trichosanthis 20g
Rhizoma Coptidis 15g Fructus Corni 20g Radix Et Caulis Acanthopanacis Senticosi 20g
Rhizoma Polygonati 25g Radix Rhodiolae 20g Rhizoma Gastrodiae 30g
Fructus Lycii 30g Rhizoma Chuanxiong 20g Rhizoma Anemarrhenae 20g
Flos Inulae 25g Radix Ginseng 15g white sugar 30g
65% alcoholic solution 20g.
The preparation method of above-mentioned hypoglycemic Chinese medicine prepn, comprises the steps:
1), Radix Rehmanniae, Cortex Mori, Cortex Lycii, Stigma Maydis, Radix Trichosanthis, Rhizoma Coptidis, Herba Epimedii, Radix Et Caulis Acanthopanacis Senticosi are prepared in proportion, pulverize and cross 80 mesh sieves through pulverizer, then under the high temperature of 50-70 DEG C, dry, the room temperature of then naturally drying in the air is for subsequent use;
2), the mixture of powders of Radix Rehmanniae, Cortex Mori, Cortex Lycii, Stigma Maydis, Radix Trichosanthis, Rhizoma Coptidis, Herba Epimedii, Radix Et Caulis Acanthopanacis Senticosi in above-mentioned steps is added pure water decoct three times, add for the first time 10 times of water gagings to decoct half an hour, add for the second time 5 times of water gagings to decoct 20 minutes, add for the third time 5 times of water gagings to decoct 10 minutes, then collecting decoction filtration, for subsequent use;
3), Rhizoma Polygonati, Radix Rhodiolae, Rhizoma Gastrodiae, Fructus Lycii, Rhizoma Chuanxiong, the Rhizoma Anemarrhenae, Flos Inulae, Radix Ginseng are prepared in proportion, pulverize and cross 80 mesh sieves through pulverizer, then under the high temperature of 50-70 DEG C, dry, the room temperature of then naturally drying in the air is for subsequent use;
4), by the mixture of powders of above-mentioned Rhizoma Polygonati, Radix Rhodiolae, Rhizoma Gastrodiae, Fructus Lycii, Rhizoma Chuanxiong, the Rhizoma Anemarrhenae, Flos Inulae, Radix Ginseng add 10 times of amounts pure water decoct half an hour, then get decocting liquid and filter, for subsequent use;
5), under room temperature state, by above-mentioned steps 2) and step 4) in the decocting liquid that obtains mix, and add 65% alcoholic solution and stir, form Chinese medicine composition pharmaceutical solutions;
6), by above-mentioned steps 5) in Chinese medicine composition pharmaceutical solutions add white sugar, and stir 5 minutes, can make.
The above-mentioned Chinese medicine composition pharmaceutical solutions of producing can be for oral, if can respectively drink once and long-term drink better effects if the morning, noon and afternoon.
Theoretical foundation of the present invention is:
Radix Rehmanniae is the tuber of scrophulariaceae rehmannia glutinosa plant.Sweet in the mouth, hardship, cold in nature, enter the heart, liver, kidney channel, can be used for controlling fever due to yin deficiency, quench one's thirst, spit blood, epistaxis, metrorrhagia, menoxenia, frequent fetal movement, the moon is hindered constipation etc., effective in cure to reducing blood glucose, and can suppress experimental hyperglycemia, and its sugar-lowering components is rehmanin.With other drug matchings of the present invention, evident in efficacy.
Cortex Mori is the root bark of moraceae plants Mulberry.Main product in Anhui, the ground such as Henan, Zhejiang, Jiangsu, Hunan.Effect has eliminating pathogen from the lung for relieving asthma, inducing diuresis to remove edema.For lung-heat cough with asthma, the edema of the face, the diseases such as dysuria.Research worker continues and isolates moranoline from Cortex Mori the seventies in last century, and after confirming that it has hypoglycemic activity, has again people to isolate blood sugar lowering material moran A from Cortex Mori, and it is a kind of glycoprotein, the about 7.5x10' of molecular weight, and protein part accounts for 57.4%.Experiment confirms that moran A has dose-dependent blood sugar decreasing effect to the hyperglycemia mice of model induced by alloxan, if taking the relative blood sugar level of hyperglycemia group as 100%, give respectively lnor; LnA3,10,30m/kg, after 7h, blood sugar level reduces to respectively 61%, 38%, 34%, is respectively 77%, 66%, 49% after 24h.Research finds, compound recipe Cortex Mori concentrated solution large (30 red kg), in (15g/kg) dosage group alloxan induced mice diabetes are had to obvious blood sugar reducing function, glucose hyperglycemia is had to certain blood sugar reducing function.
Cortex Lycii is the root bark of matrimony vine of solanaceae plant.Can be used as medicine, cold in nature, sweet in the mouth.Have removing heat from blood except effects such as treasure, lung heat clearing pathogenic fire reducing, pharmacological research shows, Cortex Lycii has obvious blood pressure lowering and the effect of reduction blood glucose.Gavage Cortex Lycii decoct to rabbit, first make the blood glucose short time raise, then reduce lastingly.
Stigma Maydis, Stigma Maydis is the zeistic style of grass and stigma, has another name called maize palpus, nature and flavor are sweet, flat, return stomach, gallbladder, all warps of kidney, have effect of diuresis, detumescence, heat clearing away, reducing pressure and sugar.Cure mainly that diabetes are thirsty, polyuria person.
Radix Trichosanthis, the acid of nature and flavor sweetness and bitterness is cool, returns lung kidney channel, has promoting the production of body fluid to quench thirst, stomach reinforcing pathogenic fire reducing the effect such as to moisturize.China's medical book ancient books " herbal classic " is said: main quenches one's thirst, fever of the body, stuffy sensation with restlessness, hot greatly, and tonify deficiency regulating the spleen and stomach.Normal and the Rhizoma Anemarrhenae of Radix Trichosanthis, Rhizoma Dioscoreae, Radix Ophiopogonis, Fructus Lycii, Radix Astragali compatibility, cure mainly YIN-deficiency type diabetes.
Rhizoma Coptidis, herbaceos perennial, belongs to Ranunculaceae Coptis.Rhizoma Coptidis bitter in the mouth, cold, nontoxic.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.According to clinical report, the Berberine in treating diabetes that include can make blood glucose obviously reduce, and Rhizoma Coptidis water decoction can reduce the blood glucose of normal mouse and alloxan diabetes Mus.Experiment shows, the blood sugar lowering mechanism of berberine does not affect secretion and the release of insulin, does not affect number and the affinity of Hepatocyte Insulin yet, but by suppressing gluconeogenesis and promoting that glycolysis produces blood sugar reducing function.
Fructus Corni, sour in the mouth, puckery, tepor.Return liver, kidney channel, can liver and kidney tonifying, restrain astringent or styptic treatment for spontaneous sweating, controlling nocturnal emission with astringent drugs reducing urination, leukorrhagia stopping only collapses, hidroschesis also has promoting the production of body fluid to quench thirst in addition, for soreness of waist and knee joint, dizziness and tinnitus, forgetful emission and spermatorrhea, enuresis frequent micturition, bleeding not during menses menoxenia, profuse sweating collapse, the interior-heat disease such as quench one's thirst.
Radix Et Caulis Acanthopanacis Senticosi, acrid in the mouth, hardship, micro-sweet, warm in nature, return Liver Channel, kidney channel.Function is wind-damp dispelling, invigorating the liver and kidney, and bone and muscle strengthening, the arteries and veins of invigorating blood circulation, cures mainly anemofrigid-damp arthralgia, lumbocrural pain, muscles and bones flaccidity is soft, is slow in action, a little less than body weakness with emaciation, traumatic injury, fracture, edema, beriberi, uncontrolled urination is itched etc., and with other drug matchings of the present invention, blood sugar decreasing effect is obvious.
Rhizoma Polygonati, has another name called Rhizoma Polygonati Cirrhifolii, Caput Gallus domesticus ginseng.For the dry rhizome of liliaceous plant Yunnan Rhizoma Polygonati, Rhizoma Polygonati or Polygonatum cyrtonema Hua, Rhizoma Polygonati sweet in the mouth is flat.Return lung, spleen, kidney channel.Can nourishing kidney lung moistening, invigorating the spleen and replenishing QI.
Radix Rhodiolae, perennial herb, high 10-20 centimetre.Root is sturdy, conical, meat, isabelline, the most fibrous roots of collar portion tool, Radix Rhodiolae is dry root and the rhizome of crassulaceae plants Radix Rhodiolae, effect of Radix Rhodiolae and effect are energy the kidney invigorating, regulate the flow of vital energy and nourish blood, and have promoting blood circulation and hemostasis, clearing away lung-heat to relieve cough, antipyretic, and effect under leukorrhagia stopping, the side effect of Radix Rhodiolae is not temporarily found.
Rhizoma Gastrodiae, is herbaceos perennial, is distributed in national most areas.Its dry tuber also claims Rhizoma Gastrodiae, is to commonly use and famousr and precious Chinese medicine simply, and the diseases such as clinical dizzy, the numb limbs and tense tendons of being used for having a headache, infantile convulsion, epilepsy, tic, tetanus are can suppressing the hyperactive liver flame-out, is applicable to headache due to excessive rising of liver-YANG, the disease such as dizzy.
Fructus Lycii, returns Liver Channel, kidney channel, lung meridian.Fructus Lycii is mended and oiliness, has the merit of enriching yin and nourishing kidney, replenishing vital essence to improve eyesight, promoting the production of body fluid to quench thirst, tonifying both YIN and YANG.Compatibility Fructus Schisandrae Chinensis, Rhizoma Polygonati, Radix Scrophulariae, be applicable to relatively deficiency of the liver and kindey person, can improve the symptom of quenching one's thirst.
Rhizoma Chuanxiong, a kind of Chinese medicinal plant, is usually used in blood-activating and qi-promoting, wind-expelling pain-stopping, Main Cultivation in Sichuan, the ground such as Yunnan, Guizhou, Guangxi, Hubei.The pungent temperature of Rhizoma Chuanxiong is fragrant dry, walks and does not keep, can go loose, the up top, mountain peak that reaches; Enter again blood system, the descending sea of blood that reaches.Blood circulation promoting and blood stasis dispelling effect is extensive, the various diseases of suitable stagnation of blood stasis; Wind-expelling pain-stopping, effectiveness is excellent, can control the diseases such as wind syndrome of head headache, rheumatic arthralgia.It is the gas medicine in blood that former times people calls Rhizoma Chuanxiong, nearly says the functions such as pungent loose, the resolving depression of its residence, sensible, pain relieving.
The Rhizoma Anemarrhenae, these product are the dry rhizome of the monocotyledon Liliaceae Rhizoma Anemarrhenae, effect clearing away heat-fire, promotes the production of body fluid and moisturizes.Clearing away heat-fire, promotes the production of body fluid and moisturizes.For fever caused by exogenous pathogenic factors, high hot excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, dryness of the intestine constipation.
Flos Inulae, has another name called donkey grass, Flos Inulae.Perennial herb, stem tool is indulged rib, green or micro-band aubergine.Leaf alternate, ellipse, ellipticity lanceolar or long narrow ellipse.Head inflorescence minority or majority, top is raw, is umbrella room shape and arranges, and Flos Inulae is salty, warm, slightly poisonous, for expectorant, the therapeutic method to keep the adverse QI flowing downwards, softening the hard mass, row water.
Radix Ginseng, herbaceos perennial, the weather that happiness is shady and cool, moistening, grows in the theropencedrymion or shaw of height above sea level gentle slope, 500~1100 meters of mountain regions that day and night temperature is little or slope land more.Radix Ginseng can promote laboratory animal blood glucose to reduce, and can reduce the rising of glycosuria blood fat and unable symptom.Clinical report Radix Ginseng extractum has therapeutic effect to early stage light disease diabetes, and glucose in urine is reduced, and blood glucose reduces by 40 milligrams, and after drug withdrawal, curative effect is still sustainable more than 2 weeks.
65% alcoholic solution spirituosity, Chinese liquor have the title of " length of hundred medicines ", Chinese liquor stable in properties, safe and effective, and because ethanol is a kind of good semi-polarity organic solvent, the various effective ingredient of Chinese medicine are all soluble in wherein, wine assisting drug, wine help medicine gesture and give full play to its effect, improve therapeutic effect.
Diabetes are that doctor trained in Western medicine does not have particularly preferred treatment way to diabetes at present, is referred to as incurable disease because hypoinsulinism causes the too high dysbolismus of blood glucose.And China's Chinese medicine has very original Therapeutic Method to diabetes, for example these medicines of the present invention are used in conjunction with and have triple role, it is blood glucose inhibitor, it is again euglycemic agent, strengthen again Insulin receptor INSR function simultaneously, and effect stability, preparation safety of the present invention has no side effect, be applicable to long-term taking, without going on a diet, do not aviod certain food, without taking other hypoglycemic medicine, take separately, can effectively safeguard islets of langerhans, reduce blood glucose, improve immunity, Western medicine is also treated hyperglycemia at present, only regulating and controlling blood sugar in fact, can not start with from the conditioning of function of human body, and Chinese medicine effect relaxes, stabilizing blood sugar effect is better, the present invention is particularly useful in early days, person in middle and old age's hyperglycemic patients.
In the situation that technical solution of the present invention does not disclose, carry out a series of clinical trial.Preparation of the present invention needs to take for 1 hour after the meal, and every day 3 times, each 300ml, 1 month was 1 course for the treatment of, and two courses for the treatment of are as observation of curative effect.Obtain through clinical test results, hypoglycemic important preparation provided by the present invention, has obvious blood sugar lowering, improves the curative effect of disease.Enumerate several typical cases below and take process and the corresponding curative effect of preparation of the present invention.
case of illness introduce 1:
Zhang, man, 57 years old, private storekeeper, diabetes medical history has 8 years.In early days, symptom is lighter, and whole blood blood glucose is 6.8 mM/ls on an empty stomach, comparatively steady, but nearest 3 years, disease is comparatively serious, and whole blood blood glucose reaches 9.7 mM/ls on an empty stomach, and with dehydration phenomenon.Many-side is sought medical advice for many years, can only control comparatively slowly disease development, but not have preferably the effect of blood glucose.Take two courses for the treatment of of preparation of the present invention, blood pressure is obviously reduced, and whole blood blood glucose will be 6.6 mM/ls, the phenomenon of not dewatering on an empty stomach.Continue to take this preparation, after 2 months, blood glucose will be normal level.This preparation obtains obvious blood sugar decreasing effect.
case of illness introduce 2:
Gong, man, 51 years old, civil servant, the hyperglycemia time has 4 years, and symptom is lighter, and whole blood blood glucose is 6.6 mM/ls on an empty stomach.Comparatively significantly symptom is many for getting up in the night to urinate, and gets up in the night to urinate 2-3 time every night.Take the phenomenon of getting up in the night to urinate after two courses for the treatment of of preparation of the present invention and improve, whole blood blood glucose drops to 6.0 mM/ls on an empty stomach.The blood sugar decreasing effect of this preparation is obvious, and has no side effect.
case of illness introduce 3:
Lin, female, 60 years old, retirement was in, and diabetic history had 15 years.On an empty stomach whole blood blood sugar concentration is 12.0 mM/ls of left and right for they, and with frequent micturition, the manifest symptoms such as dehydration, thirsty, nauseating, vomiting, are comparatively serious cases.Taking after this preparation two courses for the treatment of whole blood blood glucose on an empty stomach drops to below 10 mM/ls, nauseating, symptoms of emesis alleviates, continue to take after 4 courses for the treatment of on an empty stomach whole blood glycemic control 7.8 mM/ls of left and right, and frequent micturition, thirsty phenomenon also obviously alleviate, do not have the sensation of other discomforts.Curative effect is obvious, before investigation finishes, is taking this preparation always.
case of illness introduce 4:
Yuan, man, 51 years old, suffers from diabetes 7 years, on an empty stomach 9.0 mM/ls, whole blood blood glucose.Another its blood pressure that checks, diastolic pressure 92, systolic pressure 155, with hypertension symptom.After taking other hypoglycemic medicines, blood glucose is reduced, but it is very large, unstable to rise and fall, when whole blood blood sugar concentration and higher in normal value, time and reach peaked 8.9 mM/ls, after drug withdrawal, be high state always.After taking 3 courses for the treatment of of this preparation, glycemic control, at 5.7 mM/ls, has obvious hypoglycemic effect, and its hypertensive phenomenon also improves, diastolic pressure 85, and systolic pressure 138, and without other side effect.
case of illness introduce 5:
Money, man, 50 years old, unemployed, because of also obesity of excessive drinking throughout the year, cause hyperglycemia, before 5 years, checked out that its blood glucose is higher, whole blood blood glucose is generally 8.5 mM/ls of left and right on an empty stomach for they, and significant complications is frequent micturition, xerosis cutis, control drink and moderate exercise after, its blood glucose drops to 8.0 mM/ls, but does not drop to normal value, and there is phenomenon repeatedly, taken this Chinese medicine preparation for dropping to normal value.After two courses for the treatment of, whole blood blood glucose drops to 6.8 mM/ls on an empty stomach, then drops to 6.0 mM/ls after continuing to take two courses for the treatment of, and controlled hypourocrinia, and xerosis cutis symptom alleviates, and after disconnected medicine, not bounce-back, does not have other senses of discomfort yet.Said preparation curative effect is obvious.
In conjunction with above clinical data and theoretical foundation of the present invention, visible beneficial effect of the present invention is, the preparation that the present invention makes, and blood sugar decreasing effect is obvious, and nontoxic, have no side effect, effect stability, reparation technology is simple and easy to do.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is explained detailedly:
embodiment 1:
Preparation of the present invention is the compositions liquid formulation being prepared into by pure water, Radix Rehmanniae, Cortex Mori, Cortex Lycii, Stigma Maydis, Radix Trichosanthis, Rhizoma Coptidis, Herba Epimedii, Radix Et Caulis Acanthopanacis Senticosi, Rhizoma Polygonati, Radix Rhodiolae, Rhizoma Gastrodiae, Fructus Lycii, Rhizoma Chuanxiong, the Rhizoma Anemarrhenae, Flos Inulae, Radix Ginseng, white sugar and 65% alcoholic solution, and wherein the quality proportioning of each component is:
Pure water 4000g Radix Rehmanniae 10g Cortex Mori 20g
Cortex Lycii 20g Stigma Maydis 25g Radix Trichosanthis 20g
Rhizoma Coptidis 15g Fructus Corni 20g Radix Et Caulis Acanthopanacis Senticosi 20g
Rhizoma Polygonati 20g Radix Rhodiolae 20g Rhizoma Gastrodiae 30g
Fructus Lycii 30g Rhizoma Chuanxiong 20g Rhizoma Anemarrhenae 20g
Flos Inulae 20g Radix Ginseng 10g white sugar 20g
65% alcoholic solution 15g.
The preparation method of above-mentioned hypoglycemic Chinese medicine prepn, comprises the steps:
1), Radix Rehmanniae, Cortex Mori, Cortex Lycii, Stigma Maydis, Radix Trichosanthis, Rhizoma Coptidis, Herba Epimedii, Radix Et Caulis Acanthopanacis Senticosi are prepared in proportion, pulverize and cross 80 mesh sieves through pulverizer, then under the high temperature of 50-70 DEG C, dry, the room temperature of then naturally drying in the air is for subsequent use;
2), the mixture of powders of Radix Rehmanniae, Cortex Mori, Cortex Lycii, Stigma Maydis, Radix Trichosanthis, Rhizoma Coptidis, Herba Epimedii, Radix Et Caulis Acanthopanacis Senticosi in above-mentioned steps is added pure water decoct three times, add for the first time 10 times of water gagings to decoct half an hour, add for the second time 5 times of water gagings to decoct 20 minutes, add for the third time 5 times of water gagings to decoct 10 minutes, then collecting decoction filtration, for subsequent use;
3), Rhizoma Polygonati, Radix Rhodiolae, Rhizoma Gastrodiae, Fructus Lycii, Rhizoma Chuanxiong, the Rhizoma Anemarrhenae, Flos Inulae, Radix Ginseng are prepared in proportion, pulverize and cross 80 mesh sieves through pulverizer, then under the high temperature of 50-70 DEG C, dry, the room temperature of then naturally drying in the air is for subsequent use;
4), by the mixture of powders of above-mentioned Rhizoma Polygonati, Radix Rhodiolae, Rhizoma Gastrodiae, Fructus Lycii, Rhizoma Chuanxiong, the Rhizoma Anemarrhenae, Flos Inulae, Radix Ginseng add 10 times of amounts pure water decoct half an hour, then get decocting liquid and filter, for subsequent use;
5), under room temperature state, by above-mentioned steps 2) and step 4) in the decocting liquid that obtains mix, and add 65% alcoholic solution and stir, form Chinese medicine composition pharmaceutical solutions;
6), by above-mentioned steps 5) in Chinese medicine composition pharmaceutical solutions add white sugar, and stir 5 minutes, can make.
The above-mentioned Chinese medicine composition pharmaceutical solutions of producing can be for oral, if can respectively drink once and long-term drink better effects if the morning, noon and afternoon.
embodiment 2:
The present invention also preferably raw materials quality be (gram):
Pure water 8000g Radix Rehmanniae 30g Cortex Mori 40g
Cortex Lycii 40g Stigma Maydis 35g Radix Trichosanthis 30g
Rhizoma Coptidis 25g Fructus Corni 30g Radix Et Caulis Acanthopanacis Senticosi 30g
Rhizoma Polygonati 30g Radix Rhodiolae 30g Rhizoma Gastrodiae 40g
Fructus Lycii 40g Rhizoma Chuanxiong 30g Rhizoma Anemarrhenae 30g
Flos Inulae 35g Radix Ginseng 20g white sugar 30g
65% alcoholic solution 15g.
Preparation method is as embodiment 1.
embodiment 3:
The present invention also preferably raw materials quality be (gram):
Pure water 5000g Radix Rehmanniae 15g Cortex Mori 25g
Cortex Lycii 25g Stigma Maydis 30g Radix Trichosanthis 25g
Rhizoma Coptidis 20g Fructus Corni 25g Radix Et Caulis Acanthopanacis Senticosi 25g
Rhizoma Polygonati 25g Radix Rhodiolae 25g Rhizoma Gastrodiae 35g
Fructus Lycii 35g Rhizoma Chuanxiong 25g Rhizoma Anemarrhenae 25g
Flos Inulae 25g Radix Ginseng 15g white sugar 25g
65% alcoholic solution 20g.
Preparation method is as embodiment 1.
embodiment 4:
The present invention also preferably raw materials quality be (gram):
Pure water 6000g Radix Rehmanniae 20g Cortex Mori 30g
Cortex Lycii 30g Stigma Maydis 35g Radix Trichosanthis 30g
Rhizoma Coptidis 25g Fructus Corni 30g Radix Et Caulis Acanthopanacis Senticosi 30g
Rhizoma Polygonati 30g Radix Rhodiolae 30g Rhizoma Gastrodiae 35g
Fructus Lycii 35g Rhizoma Chuanxiong 30g Rhizoma Anemarrhenae 30g
Flos Inulae 30g Radix Ginseng 20g white sugar 30g
65% alcoholic solution 25g.
Preparation method is as embodiment 1.
embodiment 5:
The present invention also preferably raw materials quality be (gram):
Pure water 7000g Radix Rehmanniae 10g Cortex Mori 20g
Cortex Lycii 20g Stigma Maydis 25g Radix Trichosanthis 20g
Rhizoma Coptidis 25g Fructus Corni 30g Radix Et Caulis Acanthopanacis Senticosi 30g
Rhizoma Polygonati 30g Radix Rhodiolae 30g Rhizoma Gastrodiae 30g
Fructus Lycii 30g Rhizoma Chuanxiong 20g Rhizoma Anemarrhenae 20g
Flos Inulae 35g Radix Ginseng 20g white sugar 20g
65% alcoholic solution 30g.
Preparation method is as embodiment 1.
embodiment 6:
The present invention also preferably raw materials quality be (gram):
Pure water 4500g Radix Rehmanniae 12g Cortex Mori 28g
Cortex Lycii 28 Stigma Maydis 28g Radix Trichosanthis 26g
Rhizoma Coptidis 18g Fructus Corni 22g Radix Et Caulis Acanthopanacis Senticosi 22g
Rhizoma Polygonati 22g Radix Rhodiolae 22g Rhizoma Gastrodiae 38g
Fructus Lycii 38g Rhizoma Chuanxiong 21g Rhizoma Anemarrhenae 21g
Flos Inulae 23g Radix Ginseng 12g white sugar 28g
65% alcoholic solution 18g.
Preparation method is as embodiment 1.
Above-described embodiment is only the several of the numerous embodiments of the present invention, and as each formula strengthened in the ratio in technical scheme or reducing dose, this blood sugar reducing preparation curative effect making is also unaffected, within also will dropping on the scope of the present invention.

Claims (4)

1. a hypoglycemic Chinese medicine prepn, it is characterized in that, preparation of the present invention is the compositions liquid formulation being prepared into by pure water, Radix Rehmanniae, Cortex Mori, Cortex Lycii, Stigma Maydis, Radix Trichosanthis, Rhizoma Coptidis, Herba Epimedii, Radix Et Caulis Acanthopanacis Senticosi, Rhizoma Polygonati, Radix Rhodiolae, Rhizoma Gastrodiae, Fructus Lycii, Rhizoma Chuanxiong, the Rhizoma Anemarrhenae, Flos Inulae, Radix Ginseng, white sugar and 65% alcoholic solution, and wherein the quality proportioning of each component is:
Pure water 4000-8000g Radix Rehmanniae 10-30g Cortex Mori 20-40g
Cortex Lycii 20-40g Stigma Maydis 25-35g Radix Trichosanthis 20-30g
Rhizoma Coptidis 15-25g Fructus Corni 20-30g Radix Et Caulis Acanthopanacis Senticosi 20-30g
Rhizoma Polygonati 20-30g Radix Rhodiolae 20-30g Rhizoma Gastrodiae 30-40g
Fructus Lycii 30-40g Rhizoma Chuanxiong 20-30g Rhizoma Anemarrhenae 20-30g
Flos Inulae 20-35g Radix Ginseng 10-20g white sugar 20-30g
65% alcoholic solution 15-30g.
2. hypoglycemic Chinese medicine prepn according to claim 1, is further characterized in that, wherein the quality proportioning of each component is:
Pure water 5000-8000g Radix Rehmanniae 10-20g Cortex Mori 20-30g
Cortex Lycii 20-30g Stigma Maydis 25-30g Radix Trichosanthis 20-25g
Rhizoma Coptidis 15-20g Fructus Corni 20-25g Radix Et Caulis Acanthopanacis Senticosi 20-25g
Rhizoma Polygonati 20-25g Radix Rhodiolae 20-25g Rhizoma Gastrodiae 30-35g
Fructus Lycii 30-35g Rhizoma Chuanxiong 20-25g Rhizoma Anemarrhenae 20-25g
Flos Inulae 20-30g Radix Ginseng 10-20g white sugar 20-30g
65% alcoholic solution 15-25g.
3. hypoglycemic Chinese medicine prepn according to claim 1 and 2, is further characterized in that, wherein the quality proportioning of each component is:
Pure water 6000g Radix Rehmanniae 15g Cortex Mori 25g
Cortex Lycii 25g Stigma Maydis 25g Radix Trichosanthis 20g
Rhizoma Coptidis 15g Fructus Corni 20g Radix Et Caulis Acanthopanacis Senticosi 20g
Rhizoma Polygonati 25g Radix Rhodiolae 20g Rhizoma Gastrodiae 30g
Fructus Lycii 30g Rhizoma Chuanxiong 20g Rhizoma Anemarrhenae 20g
Flos Inulae 25g Radix Ginseng 15g white sugar 30g
65% alcoholic solution 20g.
4. a preparation method for hypoglycemic Chinese medicine prepn, is characterized in that, it comprises the steps:
1), Radix Rehmanniae, Cortex Mori, Cortex Lycii, Stigma Maydis, Radix Trichosanthis, Rhizoma Coptidis, Herba Epimedii, Radix Et Caulis Acanthopanacis Senticosi are prepared in proportion, pulverize and cross 80 mesh sieves through pulverizer, then under the high temperature of 50-70 DEG C, dry, the room temperature of then naturally drying in the air is for subsequent use;
2), the mixture of powders of Radix Rehmanniae, Cortex Mori, Cortex Lycii, Stigma Maydis, Radix Trichosanthis, Rhizoma Coptidis, Herba Epimedii, Radix Et Caulis Acanthopanacis Senticosi in above-mentioned steps is added pure water decoct three times, add for the first time 10 times of water gagings to decoct half an hour, add for the second time 5 times of water gagings to decoct 20 minutes, add for the third time 5 times of water gagings to decoct 10 minutes, then collecting decoction filtration, for subsequent use;
3), Rhizoma Polygonati, Radix Rhodiolae, Rhizoma Gastrodiae, Fructus Lycii, Rhizoma Chuanxiong, the Rhizoma Anemarrhenae, Flos Inulae, Radix Ginseng are prepared in proportion, pulverize and cross 80 mesh sieves through pulverizer, then under the high temperature of 50-70 DEG C, dry, the room temperature of then naturally drying in the air is for subsequent use;
4), by the mixture of powders of above-mentioned Rhizoma Polygonati, Radix Rhodiolae, Rhizoma Gastrodiae, Fructus Lycii, Rhizoma Chuanxiong, the Rhizoma Anemarrhenae, Flos Inulae, Radix Ginseng add 10 times of amounts pure water decoct half an hour, then get decocting liquid and filter, for subsequent use;
5), under room temperature state, by above-mentioned steps 2) and step 4) in the decocting liquid that obtains mix, and add 65% alcoholic solution and stir, form Chinese medicine composition pharmaceutical solutions;
6), by above-mentioned steps 5) in Chinese medicine composition pharmaceutical solutions add white sugar, and stir 5 minutes, can make, the above-mentioned Chinese medicine composition pharmaceutical solutions of producing can be for oral, if can respectively drink once and long-term drink better effects if the morning, noon and afternoon.
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