CN104027542A - Liniment for nasal disease - Google Patents
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- CN104027542A CN104027542A CN201410294668.1A CN201410294668A CN104027542A CN 104027542 A CN104027542 A CN 104027542A CN 201410294668 A CN201410294668 A CN 201410294668A CN 104027542 A CN104027542 A CN 104027542A
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Abstract
The invention discloses a traditional Chinese medicine liniment. The liniment is characterized by being prepared by extracting pearl powder, borax, borneol, allium fistulosum, radix angelicae, radix ampelopsis and other effective components of traditional Chinese medicines by utilizing an extraction technology. The liniment is used for treating symptoms of cold, rhinobyon rhinorrhea, dizziness, limb weakness, bradypsychia and lapse of memory which are caused by rhinitis, nasal mucosa anabrosis, vibrissa shedding and the nasal disease. The liniment can be used for preventing nasal allergy, and cleaning and protecting the nasal cavity. The liniment can serve as a protective agent for a long time for a user under a poor working and living environment.
Description
Technical field
The invention belongs to tcm field, relate to a kind of rhinitis, nasal mucosa, vibrissa liniment of nose diseases such as come off for the treatment of.
Background technology
Nose is often subject to the impact of extraneous undesirable element, and the infection that various diseases microorganism easily occurs can cause the inflammation of boil of the nose, nasal vestibulitis, nose and paranasal sinuses; Nasal cavity is the door that allergen enters body, is again the position that allergic disease occurs, so the inflammation of the bronchia mucosal that virus, antibacterial, allergen, various physical and chemical factor and some systemic disease cause is commonly encountered diseases.Its main pathological change is bronchia mucosal hyperemia, swelling, ooze out, hypertrophy, atrophy or downright bad etc.Nose adjoins with cranial cavity, eye socket and oral cavity on dissecting, and the disease of nasal vestibule, nose and paranasal sinuses can cause severe complication, as meningitis, orbital cellulitis etc.; By blood, can cause cavernous sinus infection, severe patient can be blind, even threat to life.
Nasal system disease, except operative treatment, is exactly mainly drug treatment, and applying at present maximum is exactly intranasal glucocorticoid, belongs to and has good antiinflammatory action, and finally produce congestion effect.Can apply the long period as required.Subject matter is exactly that chemicals develops immunity to drugs with being easy to for a long time, and hormone medicine can interfere people's hormone in vivo environment, affects human body metabolic system, is easy to cause various diseases.
Motherland's medical science is of long standing and well established, has had deep understanding very early for nose diseases.Chinese medicinal liniment of the present invention, through studying for many years traditional Chinese medical science ancient books, by parts of generic medicinal plants simple formulation, formed, again through clinical excess syndrome for many years, accumulation clinical case is countless, and the situations such as flu that this Chinese medicinal liniment comes off for rhinitis, allergic rhinitis, nasal mucosa, vibrissa and cause thus, nasal obstruction rhinorrhea, dizziness, limbs fatigue, spirit is not good enough, hypomnesis that confirm have good therapeutical effect, and crude drug source is convenient, low price, common people can afford to use.
Technology contents
The flu that object of the present invention provides a kind of and treats rhinitis, nasal mucosa, vibrissa comes off and caused by nose diseases, nasal obstruction rhinorrhea, dizziness, limbs fatigue, spirit is not good enough, the Chinese medicinal liniment of hypomnesis symptom.This liniment also can be used for preventing nasal cavity irritated, clean protection.To poor can be for a long time the using when protective agent of work living environment.
Chinese medicinal liniment of the present invention is made with modern high technology effective component extracting by following raw material of Chinese medicine: Margarita powder, Borax, Borneolum Syntheticum, Bulbus Allii Fistulosi, the Radix Angelicae Dahuricae, Radix Ampelopsis.
Chinese medicinal liniment of the present invention, the weight portion proportioning of each active component is: 7 parts of Margarita powder, 5 parts of Boraxs, 3 parts of Borneolum Syntheticums, 9 parts of Bulbus Allii Fistulosi, 16 parts of the Radixs Angelicae Dahuricae, 10 parts of Radix Ampelopsis.
Chinese medicinal liniment of the present invention, effect is as follows: antiphlogistic antibacterial, antiviral, anti-flu, repairs nasal mucosa, inspires vibrissa regeneration, and the refreshment of allaying excitement, regains the strength of memory, and strengthens premunition.
Chinese medicinal liniment of the present invention, operation instruction: apply ointment with cotton swab, every day three times, body constitution immunity poor person can put on the skin more.
Chinese medicinal liniment of the present invention, follows the tracks of a large amount of clinical uses for many years, and various crowd use, has good treatment curative effect, not yet finds at present any side effect.
Points for attention in Chinese medicinal liniment use procedure of the present invention: because nasal cavity is at the nearly brain of head, mankind's health care is not despised, be the main cause of sub-health population, according to data show, continent men and women, old and young, evenly send out rate and reach the 87, the 6%th, health etc. a killer.Because patient has frequently constantly secretions outflow in a small amount at nasal mucosa place, this secretions accumulates long generation variation of time in nasal sinuses.
Medicament composing prescription of the present invention, with reference to plurality of medical pharmacopeia, is aided with the optimization of clinical application for many years simultaneously, has overcome the problem of taboo combination, specifically selects the pharmacological basis of medical herbs to be:
Margarita powder: Margarita is medicinal in existing more than 2000 history of China.Medical book < < Mingyi Bielu > > during three states, the < < book on Chinese herbal medicine in beam generation is through collection > >, the < < Haiyao Bencao, Oversea Materia Medica > > of the Tang Dynasty, the < < Kaibao Bencao > > of Song dynasty, the < < Compendium of Materia Medica > > of the Ming Dynasty, 19 kinds of medical ancient books such as the < < Thunder God Yaoxing Fu > > of the Qing Dynasty, all the curative effect of Margarita is had to clear and definite record.< < Compendium of Materia Medica > >: Margarita salty in the mouth is sweet cold nontoxic, relieving palpitation point order; Margarita is coated with face, makes us moist good color.Be coated with brothers, peeling skin hangnail; Pendant expectorant, except speckle, antidiarrheal; Except children's's fever (of children) accompanied by fear, peace soul; The nebulousurine of only passing out semen, separates pox and treats poison.... make gloss pure white.< < Pharmacopoeia of People's Republic of China > > and < < Chinese medicine voluminous dictionary > > all indicate: Margarita has the effects such as the arresting convulsion of calming the nerves, improving eyesight removing nebula, removing toxic substances and promoting granulation, and modern study also shows that Margarita powder all has unique effect at aspects such as improving body immunity, slow down aging, freckle removing and whitening, supplement calcium.Chinese medicinal liniment of the present invention is selected Margarita powder, purposes is that Margarita powder not only can be directly supplied with wound required nutrient substance when recovering by the position of being wound, the various trace elements that also Margarita powder can be included is transported among blood, assist human body to remove the lipid peroxide that trauma causes, accumulates, can allow and be wound position in recovery process, continue the effect that pigementation and residual cicatrix are eliminated in performance.And Margarita powder is cool in nature, for nasal cavity heat, breathe atmosphere and there is the effect of cooling preferably, be convenient to retain moisture, keep moistening, be beneficial to the metabolism transhipment of pathogenic bacteria.
Borax: sweet in the mouth, salty, cool in nature.Attach to the lung and stomach meridians.For heat-clearing and toxic substances removing, detumescence, anticorrosion, removing heat from the lung and dissipating phlegm.Be usually used in acute tonsillitis, pharyngolaryngitis, laryngopharynx swelling and pain, aphtha of the mouth and tongue, stomatitis, gingivitis, otitis media, conjunctival congestion and swelling pain, tinea versicolor, is the common medicine of department of eye illness.
Modern pharmacy studies confirm that, the main component of Borax is sodium tetraborate (Na2B4O710H2O).There is good bacteriostasis.Borax is a weak base, and it is the same with boric acid weak bacteriostasis.By flat band method, make in culture medium the Borax containing 10%, escherichia coli, bacillus pyocyaneus, anthrax bacillus, shigella flexneri, shigella, Bacillus typhi, Salmonella paratyphi, Bacillus proteus and staphylococcus, Candida albicans are all had to inhibitory action; With paper disk method, prove, Borax can also suppress diphtheria corynebacterium, cattle type Brucella, Diplococcus pneumoniae, meningococcus and Hemolytic streptococcus etc.Secondly, Borax still has effect anticorrosion and protection skin mucosa. and clinically can rinse ulcer, abscess by this product, particularly mucosa inflammation, as conjunctivitis, gastritis etc., because it be alkaline, can make mucosa de-sludging; Oral for urethra sterilization, when particularly urine is acidity, can make it to become alkalescence.
Borneolum Syntheticum: Borneolum Syntheticum acrid in the mouth, hardship, be slightly cold; GUIXIN, liver, lung meridian; Delicate fragrance a surname is loose, has the refreshment of having one's ideas straightened out, the loose poison of heat clearing away, the effect of improving acuity of vision and removing nebula.Borneolum Syntheticum main component is the crystallization obtaining in the resin of Borneolum Syntheticum and volatile oil, is to approach pure dextro Borneolum Syntheticum.< < Newly Revised Canon of Materia Medica > >: main trusted subordinate's pathogen, rheumatism is gathered, deafness, improving eyesight, goes conjunctival congestion skin nebula.< < Compendium of Materia Medica > >: treatment sore throat, headache, nose Xi, toothache, typhoid fever protrusion of the tongue, children's's pox fall into.Logical all keys, loose stagnated fire.> > is wanted in < < medical center bun: the Borneolum Syntheticum master stagnated fire of faling apart, the deep heat of energy, control infantile convulsion, expectorant fan, sore throat, swelling of the tongue, toothache, deafness, breath, conjunctival congestion cataract, pox poison cave in, parasite killing, hemorrhoid, expedite the emergence of, property is walked and is not kept, also can granulation promoting pain relieving.So loose and easily exhaust, be that YIN-cold is also after all.
Modern medicine study confirmation, Borneolum Syntheticum can be treated ulcerative stomatitis, and some ulcer or stomatocace are had to good therapeutic effect.Analgesic effect is obvious, accelerates inflammation and eliminates, and promotes that oral mucosa strips off, the healing of erosion and ulcer.Respond well to the caused mucosal injury of physical factor especially, and to the mucosal injury due to antibacterial or other complicated factors, also can bring into play auxiliary therapeutic action.Equally also can be used for treating chronic nasal cavity scorching, better to chronic simple rhinitis curative effect, also effective to chronic hypertrophic rhinitis, to atrophic rhinitis, can improve symptom.Drip the transference cure of having a stuffy nose after medicine, secretions becomes white from yellow green, and secretory volume gradually reduces.
Bulbus Allii Fistulosi: acrid in the mouth, warm in nature.Energy dredging QI between the upper and lower yang-energy, relieving the exterior syndrome by diaphoresis.Modern pharmacology Epidemiological Analysis Bulbus Allii Fistulosi has resisting pathogenic microbes effect, Bulbus Allii Fistulosi volatile ingredient etc. has bacteriostasis to diphtheria corynebacterium, tubercule bacillus, dysentery bacterium, staphylococcus and streptococcus, and this is to act on due to the enzyme system of antibacterial. water logging agent (1: 1) in vitro to trichophyton, permitted the various skin funguses such as blue achorion, Du's big belly microspore tinea bacterium difficult to understand, ulotrichy microspore's tinea bacterium, Gypsum Fibrosum sample microspore tinea bacterium, epidermophyton inguinale, epidermophyton rubrum, Kaufman-Wolf epidermophyton, star-shaped nocardia and had inhibitory action in various degree.The filtrate of Herba Alii fistulosi has the effect of the trichomonas vaginitis killed in vitro.The lymphatic temperament of Herba Alii fistulosi has protective effect to skin and mucosa in addition; its sulfur compound has slight local irritant effect, laxation effect and anthelmintic action; when its volatile ingredient is discharged by respiratory tract, sweat gland and urinary tract, can stimulate secretion, eliminate the phlegm, diaphoresis and diuresis.
The Radix Angelicae Dahuricae: the Radix Angelicae Dahuricae, for controlling nasal sinusitis key medicine, has the function of removing dampness clearing the nasal passage.Can dispel the wind again, wet dissipation, evacuation of pus, granulation promoting pain relieving; Cure mainly anemofrigid cold, forehead headache, sinusitis, toothache, anal fistula, have blood in stool, the disease such as leucorrhea, carbuncle furuncle and phyma poison, burn.Modern medicine study confirms that the Radix Angelicae Dahuricae has antipyretic, analgesia, antiinflammatory, antimicrobial, spasmolysis.
Radix Ampelopsis: function: heat-clearing and toxic substances removing; Removing obstruction for relieving pain; Promoting tissue regeneration and ulcer healing.Cure mainly: sore swollen toxin, scrofula, scalds eczema, pyrexial malaria, traumatic injury, traumatic hemorrhage.1, inhibitory action.Water logging agent (1: 3) has inhibitory action in various degree to dermatophytess such as Trichophyton concentricunm, Microsporon audouini, groin and epidermophyton rubrums in vitro.2, auxiliary analgesic activity.Radix Ampelopsis decoct itself is without analgesic activity, but can significantly strengthen RADIX ACONITI LATERALIS PREPARATA and process the analgesic activity of Radix Aconiti, antagonism RADIX ACONITI LATERALIS PREPARATA, the contraction to isolated frog heart while processing Radix Aconiti and Radix Aconiti Kusnezoffii Preparata.3, antitumaous effect.It is that JTC-26 has inhibitory action that in vitro tests is cultivated human cervical carcinoma cell, and suppression ratio is more than 90%.
Chinese medicinal liniment of the present invention, selects parts of generic medicinal plants as active component, and raw material sources are convenient, low price, and drug dose is large, and can life cycle long, medical treatment cost be low.
Clinical efficacy
1, sample information
Sample information is the patient medical record of suffering from various nose diseasess of diagnosis and treatment over several years, and the age all had from 14～73 years old, and wherein male patient is more.
2, Therapeutic Method
With cotton swab, apply ointment, every day three times, body constitution immunity poor person can put on the skin more.
3, therapeutic effect
Chinese medicinal liniment of the present invention, follows the tracks of a large amount of clinical uses for many years, and various crowd use, has good treatment curative effect, and clinical cure rate, all more than 80%, is not yet found any side effect at present.
4, model case
(1) Cai Dengshan: man, 49 years old.On May 18th, 2012 examines.Inquiring: patient main suit, suffer from nasal inflammation for many years, once multi-treatment difficulty was dug up the roots, and often dizzy giddy, myasthenia of limbs, hypomnesis, catch a cold at every turn and cough minimum 7～8 days, even wants a wheat harvesting period, and having an injection and taking medicine extension bottle falling is exactly to be difficult to.Seek medical advice rhinitis training and did laser, operative treatment in specialist hospital of many places, fails radical cure all the time.Because often taking medicine and Repeated Operation, resistance is very poor, all easy to catch cold throughout the year now, frequent Fan Zao Bu Mo, and the intestines and stomach is also very bad, and inappetence is half congealed when dry during stool.
Inspection: health is thin, green around the gills, voice are humble; Chronic consumptions body constitution.The red infiltration of two nasal cavity nasal mucosa colors, vibrissa is de-light entirely, and light red tongue is white, thick fur canescence.
Palpation: thready and weak pulse.
Treatment: with precious white rhinitis liniment; Every day 3 times.Curative effect: dizzy after applying ointment 15 days, dizzy, spiritual not good enough situation is clearly better.Nasal cavity further consultation is observed and has been turned white without transudate, then continues medication after one month, and further consultation observation nasal mucosa has been repaired and started long tiny vibrissa again.Continuation medication is checked above symptom and is all disappeared after 1 year, vibrissa is also long thick long many, all right.
(2) Jiang Xuejiao: female, 48 years old.On May 1st, 2012 examines.Inquiring: patient main suit; Find rhinitis two more than ten years, Chinese medicine, Western medicine are constantly taken, whenever Changes in weather flu just; during flu, distending pain in the head, as drum, often can be felt sick, nasal obstruction rhinorrhea; systemic pain is uncomfortable, and the temperature of having a medical check-up during flu is normal or body temperature 35 degree left and right all, and all touching difficulty heals at every turn; take medicine for many years constantly, stomach is pain also, through many hospital diagnosis, has chronic gastritis; inappetence, defecates 3-5 day once, lassitude; often insomnia and dreamful sleep, feels depressed, poor memory.
Inspection: weak, face is simple and unadorned, the face dolorosa of chronic disease, malaise, spirit is not good enough.Two nasal cavity nasal mucosa colors are light white, and rotten to the corn place infiltrates, and vibrissa is de-light entirely.
Palpation: deficient and weak pulse.
Treatment: with precious white rhinitis liniment; Every day 3 times.
Curative effect: medication is after 15 days, and nasal mucosa place is totally without transudate, and General Symptoms is clearly better.Continue medication after one month, further consultation observation nasal mucosa has been repaired and has been started long tiny vibrissa again.Continue medication and after 1 year, check above symptom and all disappear, vibrissa is also long, and thick long many all are all right.
(3) Zheng Zhicong: man, 31 years old, on May 8th, 2012 examined.Inquiring, patient main suit: from little must rhinitis sick, but as a child only can rhinorrhea, stream very fearful, also easy to catch cold, malaise, nasal obstruction, dizziness, headache, dazzled, absent minded.Therefore, reading achievement does not catch up with, and is often criticized and is scold, and sound of sighing is very pitiful Hey, just knows originally afterwards that all rhinitis had done harm to me, cannot obtain learning good result, often haves a low fever, and closely has the low grade fever everyday of seriality more than two months, often seminal emission.
Inspection: painful facial features are brown and crisp, obtained ankylosing spondylitis because of 25 years old, after 3 years, just made a definite diagnosis, and April 27 just left hospital from authoritative orthopaedics section hospital, and cervical vertebra is entirely stiff to lumbar vertebra, limitation of activity, and dysbasia, rises and sits the utmost point bitterly, prestige nose; The nasal mucus that continues to flow, the red vibrissa of nasal mucosa color takes off light, and red tongue with yellow fur Bai Xianghou is greasy, body temperature 38 degree, spontaneous perspiration, night sweat.
Palpation: arteries and veins flood is sliding.Treatment: with precious white rhinitis liniment; Every day 3 times.
Curative effect: after 15 days, nasal mucosa place is totally without transudate in medication, and General Symptoms is clearly better.Continue medication after one month, further consultation observation nasal mucosa has been repaired and has been started long tiny vibrissa again again.Give to add to the ill oral Chinese medicine 16 months, continue medication and after 1 year, check above symptom and all disappear, vibrissa is also long, and thick long many all are all right, and physical rehabilitation is strong.
(4) Liu Lixin: female, 32 years old, on May 11st, 2012 examined.Inquiring: patient main suit; Inappetence, sleep can, from sensible, just know there is rhinitis, frequent nasal obstruction phenomenon snotty, weather once change have a headache terrible, hyposmia, good and foul smellsly do not know, also can dizzy sensation not regain consciousness, myasthenia of limbs, the frequent ulcer in oral cavity, chronic pharyngolaryngitis, chronic gastritis, anti-fluidity esophagitis, defecates 2-3 days once.Once electroencephalogram was made by Duo Jia hospital, and the multiple inspections such as CT, nuclear magnetic resonance, NMR do not find that health has abnormal conditions, hypotension 50/78mHg.
Inspection: body is thin, face is yellow, and tongue is few through tongue, chronic pharyngolaryngitis (ulceration of the throat).Nasal mucosa color is white, and the moistening transudate that has is located in erosion, and vibrissa takes off light.
Feeling the pulse: thready and rapid pulse.
Treatment: with precious white rhinitis liniment; Every day 3 times, after 15 days, nasal mucosa place is totally without transudate in medication, and General Symptoms is clearly better.Continue medication after one month, further consultation observation nasal mucosa has been repaired and has been started long tiny vibrissa again again.Give to add to the ill oral Chinese medicine 16 months, continue medication and after 1 year, check above symptom and all disappear, vibrissa is also long, and thick long many all are all right, and physical rehabilitation is strong.
(5) Qiu Maobi: female, 42 years old, on May 2nd, 2012 examined.Inquiring: patient main suit; Rhinitis 5-6, show around bad, Chinese medicine Western medicine all used that rhinitis is also tight, often dizziness headache whole body is uncomfortable, weak lazyness is moving, and To Be Protected from Heat is also afraid of cold, and throat often feels to have productive cough out also to swallow not go down, cervical spondylosis, scapulohumeral periarthritis has, and the intestines and stomach one is all bad, inappetence, all day, sleepy was felt, stool day 2-3 time.Hypotension 46/75mHg.
Inspection: green around the gills, whole face speckle, light red tongue tongue body is thin thin, white and thin fur, chronic pharyngolaryngitis (ulceration of the throat), chronic expendable facial features, nasal mucosa color is light, and vibrissa comes off
Palpation: thready and weak pulse.Treatment: with precious white rhinitis liniment; Every day 3 times.
Curative effect: after 15 days, nasal mucosa place is totally without transudate in medication, and General Symptoms is clearly better.Continue medication after one month, further consultation observation nasal mucosa has been repaired and has been started long tiny vibrissa again again.Give to add to the ill oral Chinese medicine 16 months, continue medication and after 1 year, check above symptom and all disappear, vibrissa is also long, and thick long many all are all right, and physical rehabilitation is strong.
Specific embodiment
(1) accurately take in proportion 7 grams of Margarita powder, 5 grams of Boraxs, 3 grams of Borneolum Syntheticums, 9 grams of Bulbus Allii Fistulosi, 16 grams of the Radixs Angelicae Dahuricae, 10 grams of Radix Ampelopsis, add half jin of (250 grams) clear water, soak 50 minutes.
(2) fire, first boiled with high heat, continue to use slow fire boiling 1h.Cooling, filtering juice.
(3) filtering residue adds 3 liang of (150 grams) clear water, and intense fire is boiled, and slow fire is continuous to be boiled 30 minutes.
(4) cooling, filter.Merge filtered juice, under 50 degree conditions, concentrating filtrate to density is 1.2 (with respect to the density of water), weighs approximately 185 grams.
(5) 185 grams of medicine juice are added to ethanol, make to reach 65% (mass fraction) containing alcohol amount, be about 340 grams, stir, static 24h, filters again.Weigh for the second time 310 grams.Concentrating under reduced pressure, weighs 122 grams.
(6) use flowing steam sterilization 30 minutes.
(7) cooling, subpackage, obtains liniment.
Claims (3)
1. treat a Chinese medicinal liniment for nose diseases, its technical characterictic is that this Chinese medicinal liniment is comprised of following active Chinese medicine ingredients: Margarita powder, Borax, Borneolum Syntheticum, Bulbus Allii Fistulosi, the Radix Angelicae Dahuricae, Radix Ampelopsis.
2. treat as claimed in claim 1 the Chinese medicinal liniment of nose diseases, the weight portion proportioning of each active component is: 7 parts of Margarita powder, 5 parts of Boraxs, 3 parts of Borneolum Syntheticums, 9 parts of Bulbus Allii Fistulosi, 16 parts of the Radixs Angelicae Dahuricae, 10 parts of Radix Ampelopsis.
3. as described in claim 1,2, treat the Chinese medicinal liniment of nose diseases, its preparation method is: accurately take in proportion Margarita powder, Borax, Borneolum Syntheticum, Bulbus Allii Fistulosi, the Radix Angelicae Dahuricae, Radix Ampelopsis, the clear water that adds 5 times of amounts of medical material total weight parts, soak after 50 minutes, decoct 2 times, the 1st 1h, leaches medicine juice, filtering residue adds 3 times of amount clear water, continues to decoct 30 minutes.Cooling, merge filtered juice, under 50 degree conditions, concentrating filtrate to density is 1.2 (with respect to the density of water), and weighs for the first time.After weighing, add ethanol, make to reach 65% (mass fraction) containing alcohol amount, stir, standing 24h, filters again, weighs for the second time.Concentrating under reduced pressure after weighing, be concentrated into weigh for the second time 35%～40%, and with flowing steam sterilization 30 minutes, subpackage obtained liniment.
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Application publication date: 20140910 |