CN104027407B - A kind of can improve microcirculation, the easypro network that stimulates the menstrual flow, blood circulation promoting and blood stasis dispelling, the external used medicine for the treatment of rheumatic osteopathia and preparation method - Google Patents

A kind of can improve microcirculation, the easypro network that stimulates the menstrual flow, blood circulation promoting and blood stasis dispelling, the external used medicine for the treatment of rheumatic osteopathia and preparation method Download PDF

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CN104027407B
CN104027407B CN201410313520.8A CN201410313520A CN104027407B CN 104027407 B CN104027407 B CN 104027407B CN 201410313520 A CN201410313520 A CN 201410313520A CN 104027407 B CN104027407 B CN 104027407B
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stimulates
blood
radix angelicae
microcirculation
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CN104027407A (en
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杜明珠
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Tonghua siweitang Pharmaceutical Technology Co.,Ltd.
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SWISHER TONGHUA PHARMACEUTICAL CO Ltd
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Abstract

The present invention relates to a kind of topical drug or health product, a kind of can improve microcirculation, the easypro network that stimulates the menstrual flow, blood circulation promoting and blood stasis dispelling, the external used medicine for the treatment of rheumatic osteopathia and preparation method.Take Radix Saposhnikoviae, Radix Angelicae Pubescentis, Herba Epimedii, Lignum Sappan 4 taste Chinese crude drug cuts into 10-15mm section, by Fructus Liquidambaris, Rhizoma Atractylodis, Radix Angelicae Sinensis, Folium Artemisiae Argyi, Caulis Spatholobi, Rhizoma Polygoni Cuspidati, the Cortex Eucommiae, Ramulus Cinnamomi, Flos Carthami mixes with above-mentioned above 4 taste Chinese crude drugs, put in circumfluence distillation tank, soak 1 hour, heating and refluxing extraction 5 hours, it is concentrated into proportion 1.15-1.20, 80 DEG C of drying, it is ground into fine powder, fine powder is placed in granulator granulation, wet granular is dried, temperature controls at 45 ± 5 DEG C, 2-3 minute time, dried granule is placed in oscillating granulator with 16 eye mesh screen granulate, pack and get final product.Health care: improve microcirculation.Being applicable to because of rheumatism strain caused waist, lower limb, shoulder, neck joint pain, hyperosteogeny etc. causes the crowd of microcirculation disturbance to use.

Description

A kind of can improve outside microcirculation, the easypro network that stimulates the menstrual flow, blood circulation promoting and blood stasis dispelling, treatment rheumatic osteopathia By medicine and preparation method
Technical field
The present invention relates to a kind of topical drug, health product and preparation method, specifically one to improve microcirculation, stimulate the menstrual flow Easypro network, blood circulation promoting and blood stasis dispelling, the external used medicine for the treatment of rheumatic osteopathia and preparation method (trade name: this prestige board active bubble lower limb granule).
Background technology
In prior art, treating because of rheumatism strain caused waist, lower limb, shoulder, neck joint pain, hyperosteogeny etc. causes micro-following The medicine of ring obstacle is mostly oral formulations, too much takes and not only has an impact Liver and kidney function, also has the biggest stimulation to stomach Property.Chinese crude drug external and plus suitable using method, reaches equally to improve and microcirculatory has no report.
Summary of the invention
It is an object of the invention to provide one can improve microcirculation, the easypro network that stimulates the menstrual flow, blood circulation promoting and blood stasis dispelling, control for above-mentioned deficiency Treat external used medicine and the preparation method of rheumatic osteopathia.
The technical solution of the present invention is: one can improve microcirculation, the easypro network that stimulates the menstrual flow, blood circulation promoting and blood stasis dispelling, treatment rheumatic bone Sick external used medicine, it is made up of the crude drug of following parts by weight: Fructus Liquidambaris 7~11 parts, Radix Saposhnikoviae 7~10 parts, Rhizoma Atractylodis 7~10 Part, Radix Angelicae Sinensis 7~10 parts, Folium Artemisiae Argyi 7~10 parts, Radix Angelicae Pubescentis 7~10 parts, Caulis Spatholobi 7~10 parts, Rhizoma Polygoni Cuspidati 7~10 parts, Herba Epimedii 7~10 Part, the Cortex Eucommiae 7~10 parts, Ramulus Cinnamomi 3~5 parts, Flos Carthami 3~5 parts, Lignum Sappan 3~5 parts.
Preferably: a kind of can improve microcirculation, the easypro network that stimulates the menstrual flow, blood circulation promoting and blood stasis dispelling, the external used medicine for the treatment of rheumatic osteopathia, its by with The crude drug of lower parts by weight makes granule: Fructus Liquidambaris 10 parts, Radix Saposhnikoviae 8 parts, Rhizoma Atractylodis 8 parts, Radix Angelicae Sinensis 8 parts, Folium Artemisiae Argyi 8 parts, Radix Angelicae Pubescentis 8 Part, Caulis Spatholobi 8 parts, Rhizoma Polygoni Cuspidati 10 parts, Herba Epimedii 10 parts, the Cortex Eucommiae 10 parts, Ramulus Cinnamomi 4 parts, 4 parts of Flos Carthami, Lignum Sappan 4 parts.
Preferably: a kind of can improve microcirculation, the easypro network that stimulates the menstrual flow, blood circulation promoting and blood stasis dispelling, the external used medicine for the treatment of rheumatic osteopathia, its by with The crude drug of lower parts by weight makes granule: Fructus Liquidambaris 7 parts, Radix Saposhnikoviae 9 parts, Rhizoma Atractylodis 9 parts, Radix Angelicae Sinensis 9 parts, Folium Artemisiae Argyi 9 parts, Radix Angelicae Pubescentis 9 parts, Caulis Spatholobi 9 parts, Rhizoma Polygoni Cuspidati 8 parts, Herba Epimedii 8 parts, the Cortex Eucommiae 8 parts, Ramulus Cinnamomi 5 parts, 5 parts of Flos Carthami, Lignum Sappan 5 parts.
Pharmaceutical dosage form is not limited to this, by the pharmaceutical carrier that above-mentioned each medicinal raw material is conventional with in pharmacy, such as excipient or auxiliary Material can be mixed and made into granule, powder, liquid preparation or other conventional external preparation.
A kind of preparation method of the external used medicine that can improve microcirculation, the easypro network that stimulates the menstrual flow, blood circulation promoting and blood stasis dispelling, treatment rheumatic osteopathia, Its step is as follows:
Take Radix Saposhnikoviae, Radix Angelicae Pubescentis, Herba Epimedii, Lignum Sappan 4 taste Chinese crude drug cut into 10-15mm section, by Fructus Liquidambaris, Rhizoma Atractylodis, Radix Angelicae Sinensis, Folium Artemisiae Argyi, Caulis Spatholobi, Rhizoma Polygoni Cuspidati, the Cortex Eucommiae, Ramulus Cinnamomi, Flos Carthami mix with above-mentioned above 4 taste Chinese crude drugs, put in circumfluence distillation tank, add water Soak 1 hour, add the water soaking 1 hour of 5 times amount, be concentrated into proportion 1.15-1.20,80 DEG C of drying, be ground into fine powder, will be thin Powder is placed in efficient wet mixer-granulator, after being dry mixed 3 ~ 5 seconds, adds 75 80% ethanol and does wetting agent, wet mixing 30 seconds, use Oscillating granulator is pelletized with 20 eye mesh screens, is sent into by wet granular in boiling drier and dries, and temperature controls at 45 ± 5 DEG C, the time 23 minutes, dried granule is placed in oscillating granulator with 16 eye mesh screen granulate, after the assay was approved, uses medicine bag Dress composite membrane packs, every packed 20g, and the most box-packed 3 bags (or 5 bags, 6 bags, 7 bags) load big case and get final product.
Fructus Liquidambaris: dispelling, collateral-activating, diuretic, stimulates the menstrual flow.For arthralgia, numbness contracture, edema distension, breast is few, amenorrhea.
Radix Saposhnikoviae: expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion.For headache due to common cold, rheumatic arthralgia, rubella pruritus, tetanus.
Rhizoma Atractylodis: drying damp and strengthening spleen, expelling wind and cold, improving eyesight.For retention of dampness in middle-JIAO, distension and fullness in the abdomen, have loose bowels, edema, tinea pedis flaccidity, Rheumatic arthralgia, anemofrigid cold, nyctalopia, eyes dusk is puckery.
Radix Angelicae Sinensis: replenishing and activating blood, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizziness cardiopalmus, menoxenia, amenorrhea pain Warp, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores, dryness of the intestine constipation.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, Rheumatic arthralgia, injury from falling down.
Folium Artemisiae Argyi: warming the meridian for stopping bleeding, dispersing cold for relieving pain;External removing dampness to relieve itching.For spitting blood, epistaxis, metrorrhagia menorrhagia, under vaginal bleeding during pregnancy Blood, few abdomen cold type of pain, coldness and unbalance in meridians, cold womb is infertile;External treatment skin pruritus.Vinegar Chinese mugwort charcoal warming the meridian for stopping bleeding is hemorrhage for deficient cold type.
Radix Angelicae Pubescentis: expelling wind and removing dampness, numbness relieving and pain relieving.For anemofrigid-damp arthralgia, lumbocrural pain, few the moon volt wind headache, wind and cold holds wet head under the arm Bitterly.
Caulis Spatholobi: blood circulation promoting and enriching, menstruction regulating and pain relieving, relaxing muscles and tendons and activating QI and blood in the collateral.For menoxenia, dysmenorrhea, amenorrhea, rheumatic arthralgia, fiber crops Wood paralysis, blood deficiency and yellow complexion.
Rhizoma Polygoni Cuspidati: dampness removing jaundice eliminating, heat-clearing and toxic substances removing, eliminating stasis to stop pain, relieving cough and resolving phlegm.For jaundice due to damp-heat, stranguria with turbid discharge, leukorrhagia, rheumatism Arthralgia pain, carbuncle sore tumefacting virus, burn due to hot liquid or fire, amenorrhea, abdominal mass, traumatic injury, cough due to lung-heat.
Herba Epimedii: kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.For kidney yang deficiency, impotence and seminal emission, muscles and bones flaccidity is soft, rheumatic arthralgia, Numbness contracture.
The Cortex Eucommiae: invigorating the liver and kidney, bone and muscle strengthening, antiabortive.For deficiency of the liver and kindey, soreness of waist and knee joint, muscles and bones is unable, has a dizzy spell, gestation Leakage blood, frequent fetal movement.
Ramulus Cinnamomi: diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian.Supporing yang activating QI, the flat gas that spins.For anemofrigid cold, coldness and pain in the epigastrium, cold in blood warp Close, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.
Flos Carthami: latus rectum of invigorating blood circulation, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, abdominal mass mass in the abdomen, breast side of body twinge, traumatic injury Damage, skin infection swells and ache.
Lignum Sappan: blood circulation promoting and blood stasis dispelling, subduing swelling and relieving pain.For traumatic injury, the injury of tendon and muscle of fracturing, the stasis of blood is stagnant to swell and ache, amenorrhea dysmenorrhea, puerperal the stasis of blood Resistance, chest and abdomen twinge, ulcer sore pain.
Composition principle: this prescription is Chinese medicine preparation, uses Fructus Liquidambaris, Radix Saposhnikoviae, Rhizoma Atractylodis, Radix Angelicae Sinensis, Folium Artemisiae Argyi, Radix Angelicae Pubescentis, Caulis Spatholobi Deng the mutual compatibility of medicine, reach to improve microcirculatory health care or therapeutical effect.Fructus Liquidambaris dispelling, collateral-activating, diuretic in side, stimulate the menstrual flow, anti- Wind expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion, Rhizoma Atractylodis are drying damp and strengthening spleen, expelling wind and cold, improving eyesight, Chinese angelica blood supplementing is invigorated blood circulation, menstruction regulating and pain relieving, profit Intestinal relieving constipation, Folium Artemisiae Argyi warming the meridian for stopping bleeding, dispersing cold for relieving pain, external removing dampness to relieve itching, Radix Angelicae Pubescentis expelling wind and removing dampness, numbness relieving and pain relieving, continue to use thousand in addition Caulis Spatholobi live relaxing muscles and tendons and activating QI and blood in the collateral, Rhizoma Polygoni Cuspidati dampness removing jaundice eliminating, heat-clearing and toxic substances removing, eliminating stasis to stop pain, Herba Epimedii kidney-replenishing, bone and muscle strengthening, wind-damp dispelling, Cortex Eucommiae invigorating the liver and kidney, bone and muscle strengthening, Ramulus Cinnamomi diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, the Flos Carthami that can be used for health food only invigorates blood circulation latus rectum, dissipating blood stasis Bitterly, Lignum Sappan blood circulation promoting and blood stasis dispelling, subduing swelling and relieving pain, use for reference Traditional Chinese medical theory, use circumfluence distillation technology, that extracts in medicine is effective Composition, makes granule.By the way of with hot-water soak both legs and both feet, utilize also exist on the both legs of people and both feet dirty with each The echo area (acupuncture point) that internal organs organ is corresponding, stimulates these echo areas, reaches to improve microcirculatory health care.
Health care: improve microcirculation.
Suitable population: being applicable to because of rheumatism strain caused waist, lower limb, shoulder, neck joint pain, hyperosteogeny etc. causes microcirculation The crowd of obstacle uses.
Using method: put into by plastic bag in bucket, takes this product one bag and pours in plastic bag, adds the warm water of about 40 DEG C 2-2.5Kg makes bubble lower limb grain dissolution, adds the warm water of about 40 DEG C in bucket, and both legs are put in plastic bag, plastic bag mouth envelope folding In above knee, form gas in making steam plastic bag below knee and steam, may advantageously facilitate kneed blood circulation and skin Skin absorbs, and the 30-35 minute lower limb time of bubble is advisable, and continuous using effect is more preferable.
Advantages of the present invention: the medical material effective ingredient 1, making product of the present invention uses circumfluence distillation technology, extracts medicine Active ingredient in thing, has receipts cream rate high, and energy consumption reduces, and extract quality such as significantly improves at the advantage.2, the health care of the present invention Articles for use are through Jilin Province's sanitary monitoring and testing work Spot detection, to rat skin acute toxicity test LD50More than 5000mg/kg, its poison Property classification belongs to actual nontoxic level;It is nonirritant to rabbit skin repeatedly irritation test;Guinea pig skin allergy is tried Test as weak sensitization;Improved mice microcirculation test, conclusion is to have to improve mice microcirculation.3, inventive article is straight Connect for external preparation for skin, improve the safety of clinical application.This prestige board active bubble lower limb granule always having in 50 example user Efficiency is 92%, obvious effective rate 12%, and result shows, the health care of this prestige board active bubble lower limb granule, therapeutic efficiency definitely, and have no adverse reaction Event.
Detailed description of the invention
Embodiment 1
A kind of can improve microcirculation, the easypro network that stimulates the menstrual flow, blood circulation promoting and blood stasis dispelling, the external used medicine for the treatment of rheumatic osteopathia, it is by following heavy The crude drug of amount number makes granule: Fructus Liquidambaris 10 parts, Radix Saposhnikoviae 8 parts, Rhizoma Atractylodis 8 parts, Radix Angelicae Sinensis 8 parts, Folium Artemisiae Argyi 8 parts, Radix Angelicae Pubescentis 8 parts, chicken Caulis seu Radix Schisandrae Henryi 8 parts, Rhizoma Polygoni Cuspidati 10 parts, Herba Epimedii 10 parts, the Cortex Eucommiae 10 parts, Ramulus Cinnamomi 4 parts, 4 parts of Flos Carthami, Lignum Sappan 4 parts.
Preparation method: take Radix Saposhnikoviae, Radix Angelicae Pubescentis, Herba Epimedii, Lignum Sappan 4 taste Chinese crude drug cut into 10-15mm section, by Fructus Liquidambaris, grey Art, Radix Angelicae Sinensis, Folium Artemisiae Argyi, Caulis Spatholobi, Rhizoma Polygoni Cuspidati, the Cortex Eucommiae, Ramulus Cinnamomi, Flos Carthami mix with above-mentioned above 4 taste Chinese crude drugs, put circumfluence distillation tank In, soak 1 hour, heating and refluxing extraction 5 hours, be concentrated into proportion 1.15-1.20,80 DEG C of drying, be ground into fine powder, Fine powder is placed in efficient wet mixer-granulator, after the 3-5 second is dry mixed, adds 75-80% ethanol and do wetting agent, wet mixing 30 seconds, Using oscillating granulator to pelletize with 20 eye mesh screens, sent into by wet granular in boiling drier and dry, temperature controls at 45 ± 5 DEG C, 2-3 minute time, dried granule is placed in oscillating granulator with 16 eye mesh screen granulate, after the assay was approved, medication Product composite packing film packs, every packed 20g, and the most box-packed 3 bags (or 5 bags, 6 bags, 7 bags) load big case and get final product.
Embodiment 2
A kind of can improve microcirculation, the easypro network that stimulates the menstrual flow, blood circulation promoting and blood stasis dispelling, the external used medicine for the treatment of rheumatic osteopathia, it is by following heavy The crude drug of amount number makes granule: Fructus Liquidambaris 7 parts, Radix Saposhnikoviae 9 parts, Rhizoma Atractylodis 9 parts, Radix Angelicae Sinensis 9 parts, Folium Artemisiae Argyi 9 parts, Radix Angelicae Pubescentis 9 parts, Sanguis Gallus domesticus 9 parts of rattan, Rhizoma Polygoni Cuspidati 8 parts, Herba Epimedii 8 parts, the Cortex Eucommiae 8 parts, Ramulus Cinnamomi 5 parts, 5 parts of Flos Carthami, Lignum Sappan 5 parts.
Preparation method: take Radix Saposhnikoviae, Radix Angelicae Pubescentis, Herba Epimedii, Lignum Sappan 4 taste Chinese crude drug cut into 10-15mm section, by Fructus Liquidambaris, grey Art, Radix Angelicae Sinensis, Folium Artemisiae Argyi, Caulis Spatholobi, Rhizoma Polygoni Cuspidati, the Cortex Eucommiae, Ramulus Cinnamomi, Flos Carthami mix with above-mentioned above 4 taste Chinese crude drugs, put circumfluence distillation tank In, add the water soaking 1 hour of 5 times amount, heating and refluxing extraction 5 hours, be concentrated into proportion 1.15-1.20,80 DEG C of drying, pulverizing Become fine powder, fine powder is placed in efficient wet mixer-granulator, after the 3-5 second is dry mixed, adds 75-80% ethanol and do wetting agent, wet Mixed 30 seconds, using oscillating granulator to pelletize with 20 eye mesh screens, sent into by wet granular in boiling drier and dry, temperature controls 45 ± 5 DEG C, 2-3 minute time, being placed in oscillating granulator by dried granule with 16 eye mesh screen granulate, it is qualified to check After, pack with composite membrane for packaging medicine, every packed 20g, the most box-packed 3 bags (or 5 bags, 6 bags, 7 bags), load big case and get final product.
Experimental example 1
Process choice Orthogonal experiment results is:
Factor level table
Orthogonal test designs table and result
By above-mentioned result of the test selection optimum experimental condition it is: 5 hours extraction times of medical material, the consumption of solvent is medical material 5 times.
Experimental example 2
Test crowd: age experimenter in the know 50 example between 34 years old to 65 years old.
Health care: improve microcirculation.
Suitable population: being applicable to because of rheumatism strain caused waist, lower limb, shoulder, neck joint pain, hyperosteogeny etc. causes microcirculation The crowd of obstacle uses.
Operational version: put into by plastic bag in bucket, this product of Example 1 bag is poured in plastic bag, adds 40 DEG C of left sides Right warm water 2-2.5Kg makes bubble lower limb grain dissolution, adds the warm water of about 40 DEG C in bucket, and both legs are put in plastic bag, plastics Bag mouth envelope is rolled in above knee, forms gas and steams, may advantageously facilitate kneed blood in making steam plastic bag below knee Circulation and skin absorption, steep 30-35 minute lower limb time and be advisable, and continuous using effect is more preferable.
Observing time: 14 days
Observation index: improving because of rheumatism strain caused waist, lower limb, shoulder, neck joint pain, hyperosteogeny etc. causes microcirculation to hinder The degree hindered.
Rear situation is used to be divided into: to take a turn for the better completely;
It is clearly better;
Take a turn for the better;
Slightly get better and turn;
Without improving.
Analysis and summary:
This prestige board active bubble lower limb granule is one of Traditional Chinese medicine health-care article of Tonghua Siwei Pharmaceutical Co., Ltd.'s development, tool There is the microcirculatory health care of improvement, for evaluating its safety and effectiveness, We conducted 50 examples and use crowd's test.
Result of the test shows:
50 examples use population ages between 34 years old to 65 years old, all have because of the caused waist of rheumatism strain, lower limb, shoulder, neck joint pain Bitterly, hyperosteogeny etc. cause microcirculation in various degree the most smooth.Soak both legs through this product the most daily, both feet 30-35 divides Clock, uses two weeks continuously, and its microcirculation all has improvement in various degree.
0 example taken a turn for the better completely after treatment;
Than 6 examples being clearly better before treating after treatment;
Than 21 examples taken a turn for the better before treating after treatment;
Than 19 examples turned of slightly getting better before treating after treatment;
4 examples improved than nothing before treating after treatment.
Knowable to data above, the health-care effect of this prestige board active bubble lower limb granule total effective rate in 50 example sampling survey It is 92%, obvious effective rate 12%, because the reason causing microcirculation the most smooth is different, it is suitable for the body constitution difference of crowd, this prestige board active bubble lower limb Granule improves microcirculatory effect and embodies difference.
Result of the test shows, this prestige board active bubble lower limb granule therapy, health-care effect are definite, and the event that has no adverse reaction.
Experimental example 3
Through Jilin Province's sanitary monitoring and testing work Spot detection, this prestige board active bubble lower limb granules in rats skin sensibiligen is tested LD50More than 5000mg/kg, its toxicity grading belongs to actual nontoxic level;To rabbit no skin irritation;It is weak cause to guinea pig skin Quick property.
Experimental example 4
Through Jilin Province's sanitary monitoring and testing work Spot detection, this prestige board active bubble lower limb granule improved mice microcirculation test, Conclusion is to have to improve mice microcirculation.

Claims (3)

1. one kind can be improved microcirculation, the easypro network that stimulates the menstrual flow, blood circulation promoting and blood stasis dispelling, the external used medicine for the treatment of rheumatic osteopathia, it is characterised in that by The crude drug of following parts by weight is made: Fructus Liquidambaris 7~11 parts, Radix Saposhnikoviae 7~10 parts, Rhizoma Atractylodis 7~10 parts, Radix Angelicae Sinensis 7~10 parts, Chinese mugwort Leaf 7~10 parts, Radix Angelicae Pubescentis 7~10 parts, Caulis Spatholobi 7~10 parts, Rhizoma Polygoni Cuspidati 7~10 parts, Herba Epimedii 7~10 parts, the Cortex Eucommiae 7~10 parts, osmanthus 3~5 parts of branch, Flos Carthami 3~5 parts, Lignum Sappan 3~5 parts.
2. can improve outside microcirculation, the easypro network that stimulates the menstrual flow, blood circulation promoting and blood stasis dispelling, treatment rheumatic osteopathia according to a kind of described in claim 1 With medicine, it is characterised in that made granule by the crude drug of following parts by weight: Fructus Liquidambaris 10 parts, Radix Saposhnikoviae 8 parts, Rhizoma Atractylodis 8 parts, when Return 8 parts, Folium Artemisiae Argyi 8 parts, Radix Angelicae Pubescentis 8 parts, Caulis Spatholobi 8 parts, Rhizoma Polygoni Cuspidati 10 parts, Herba Epimedii 10 parts, the Cortex Eucommiae 10 parts, Ramulus Cinnamomi 4 parts, 4 parts of Flos Carthami, Lignum Sappan 4 parts.
3. can improve outside microcirculation, the easypro network that stimulates the menstrual flow, blood circulation promoting and blood stasis dispelling, treatment rheumatic osteopathia according to a kind of described in claim 1 With medicine, it is characterised in that made granule by the crude drug of following parts by weight: Fructus Liquidambaris 7 parts, Radix Saposhnikoviae 9 parts, Rhizoma Atractylodis 9 parts, when Return 9 parts, Folium Artemisiae Argyi 9 parts, Radix Angelicae Pubescentis 9 parts, Caulis Spatholobi 9 parts, Rhizoma Polygoni Cuspidati 8 parts, Herba Epimedii 8 parts, the Cortex Eucommiae 8 parts, Ramulus Cinnamomi 5 parts, 5 parts of Flos Carthami, Soviet Union 5 parts of wood.
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