CN104000576A - Electrocardiosignal amplifier - Google Patents

Electrocardiosignal amplifier Download PDF

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Publication number
CN104000576A
CN104000576A CN201410183288.0A CN201410183288A CN104000576A CN 104000576 A CN104000576 A CN 104000576A CN 201410183288 A CN201410183288 A CN 201410183288A CN 104000576 A CN104000576 A CN 104000576A
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resistance
circuit
operational amplifier
amplifier
outfan
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CN201410183288.0A
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Chinese (zh)
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杨佩璐
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Shandong University of Traditional Chinese Medicine
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Shandong University of Traditional Chinese Medicine
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Priority to CN201410183288.0A priority Critical patent/CN104000576A/en
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Abstract

An electrocardiosignal amplifier is formed by sequentially connecting a preamplifier circuit, a band-pass filter circuit, a level uplift circuit and a 50HZ trap circuit (7) in series between an electrocardiosignal sensor and an electrocardiosignal processing system. The preamplifier circuit comprises a double-end-input double-end-output differential amplifier circuit, a common-mode sampling driver circuit, a resistance-capacitance coupling circuit and a double-end-input single-end-output differential amplifier circuit. An electrocardiosignal is amplified through the preamplifier circuit. The band-pass filter circuit composed of a high-pass filter circuit and a low-pass filter circuit is used for restraining baseline drift and eliminating serious interference caused by high-frequency harmonic waves. The level uplift circuit is designed for avoiding the distortion of the electrocardiosignal. The 50 HZ trap circuit is used for eliminating 50 HZ power-frequency interference. As amplification, filtering, level uplift and trapping are performed on the electrocardiosignal through the electrocardiosignal amplifier, the amplifier with extremely high gain is obtained. Besides, the electrocardiosignal amplifier is good in performance, high in accuracy, small in size and lower in energy consumption.

Description

A kind of ecg signal amplifier
Technical field
The present invention relates to signal amplification technique field, specifically a kind of ecg signal amplifier.
Background technology
Electrocardiosignal is a kind of typical physiology signal, has the universals of bioelectrical signals, as little in amplitude, frequency is low and be subject to external environmental interference, for gathering and measurement has brought difficulty.
Due to the various specific (special) requirements of ecg signal acquiring, conventional ecg signal amplifier is comprised of preamplifier, isolated DC high pass filter and the low-pass filter amplifier of cascade.The high speed development of current medical industry, medical treatment detection device is proposed to more and more higher requirement, to the requirement of ecg signal amplifier, be at present dynamic range that high input impedance, high-gain, high cmrr, low noise, low drift, suitable passband width and output are larger etc., but existing ecg signal amplifier cannot meet above-mentioned requirements.
Summary of the invention
For above-mentioned deficiency, the invention provides the ecg signal amplifier that a kind of performance is good, precision is high, volume is little and energy consumption is lower.
The technical solution adopted for the present invention to solve the technical problems is: a kind of ecg signal amplifier, it is characterized in that, comprise pre-amplification circuit, bandwidth-limited circuit, level lifting circuit and 50HZ trap circuit, described pre-amplification circuit, bandwidth-limited circuit, level lifting circuit and 50HZ trap circuit are connected between core signal sensor and electrocardiosignal processing system after connecting successively, to electrocardiosignal amplify, filtering, level lifting and trap process; Described pre-amplification circuit comprises the differential amplifier circuit of both-end input, both-end output, common mode sampling drive circuit, and resaistance-capacity coupling circuit, and both-end is inputted, the differential amplifier circuit of Single-end output; The double input end of the differential amplifier circuit of described both-end input, both-end output is connected with organism contact electrode, and double input end is connected with the double input end of the differential amplifier circuit of both-end input, Single-end output with resaistance-capacity coupling circuit through common mode sampling drive circuit successively; Described bandwidth-limited circuit comprises high-pass filtering circuit and low-pass filter circuit, and described high-pass filtering circuit and low-pass filter circuit are connected in series.
Preferably, the differential amplifier circuit of described both-end input, both-end output comprises the first operational amplifier U1, the second operational amplifier U2, resistance R 1, resistance R 2 and resistance R 3, described common mode sampling drive circuit comprises the 3rd operational amplifier U3, resistance R 4 and resistance R 5, described resaistance-capacity coupling circuit comprises capacitor C 1, capacitor C 2, resistance R 6 and resistance R 7, and the differential amplifier circuit of described both-end input, Single-end output comprises instrument amplifier A1 and varistor R8; The positive input of described the first operational amplifier U1 and the second operational amplifier U2 is connected with organism contact electrode respectively, series resistance R3 between reverse input end, difference series resistance R1 and resistance R 2 between the reverse input end of the first operational amplifier U1 and the second operational amplifier U2 and outfan; After the outfan series capacitance C1 of described the first operational amplifier U1, be connected with the reverse input end of instrument amplifier A1, after the outfan series capacitance C2 of described the second operational amplifier U2, be connected with the positive input of instrument amplifier A1; The positive input of described the 3rd operational amplifier U3 is connected with the outfan of the second operational amplifier U2 with the first operational amplifier U1 with resistance R 5 through resistance R 4 respectively, inverting input is connected with outfan, and outfan is connected with positive input with the reverse input end of instrument amplifier A1 with resistance R 7 through resistance R 6 respectively; Described varistor R8 is the external gain-adjusted resistance of instrument amplifier A1.
Preferably, the first described operational amplifier U1, the second operational amplifier U2 and the 3rd operational amplifier U3 all adopt LM324 integrated circuit, and described instrument amplifier A1 adopts AD620 amplifier.
Preferably, described high-pass filtering circuit comprises four-operational amplifier U4, resistance R 9 and capacitor C 3, the positive input of described four-operational amplifier U4, through resistance R 9 ground connection, is connected with the outfan of pre-amplification circuit through capacitor C 3 simultaneously, and inverting input is connected with outfan; Described low-pass filter circuit comprises the 5th operational amplifier U5, resistance R 10, resistance R 11, capacitor C 4 and capacitor C 5, the positive input of described the 5th operational amplifier U5 is through capacitor C 4 ground connection, simultaneously successively series resistance R11 with after resistance R 10 with four-operational amplifier U4 outfan be connected, inverting input is connected with outfan, after the outfan series capacitance C5 of the 5th operational amplifier U5, is connected between resistance R 10 and resistance R 11.
Preferably, described four-operational amplifier U4 and the 5th operational amplifier U5 all adopt LM324 integrated circuit.
Preferably, described level lifting circuit comprises the 6th operational amplifier U6, resistance R 12, resistance R 13, resistance R 14, resistance R 15 and adjustable resistance RW1, the positive input of described the 6th operational amplifier U6 is through resistance R 15 ground connection, after inverting input series resistance R12, be connected with the outfan of bandwidth-limited circuit, through resistance R 14, be connected with the adjustable end of adjustable resistance RW1 simultaneously, the two ends of described adjustable resistance RW1 are connected with positive and negative voltage end respectively, series resistance R13 between inverting input and outfan.
Preferably, the 6th described operational amplifier U6 adopts LM324 integrated circuit.
Preferably, described 50HZ trap circuit comprises the 7th operational amplifier U7, the 8th operational amplifier U8, resistance R 16, resistance R 17, resistance R 18, resistance R 19, resistance R 20, resistance R 21, capacitor C 6, capacitor C 7, capacitor C 8 and capacitor C 9; The positive input of described the 7th operational amplifier U7 is connected with the outfan of level lifting circuit through parallel circuit, described parallel circuit is formed in parallel by the series circuit of the series circuit of resistance R 16, resistance R 17 and capacitor C 6, capacitor C 7, and the inverting input of the 7th operational amplifier U7 is connected with outfan; The positive input of described the 8th operational amplifier U8 is connected with the outfan of the 7th operational amplifier U7 through resistance R 20, pass through resistance R 21 ground connection simultaneously, inverting input is connected with outfan, outfan is connected between capacitor C 6 and capacitor C 7 through the parallel circuit of resistance R 18 and resistance R 19, and the parallel circuit through capacitor C 8 and capacitor C 9 is connected between resistance R 16 and resistance R 17 simultaneously.
Preferably, the 7th described operational amplifier U7 and the 8th operational amplifier U8 all adopt LM324 integrated circuit.
The present invention has following outstanding beneficial effect: because electrocardiosignal is small-signal, so the present invention arranges pre-amplification circuit, amplify electrocardiosignal; In order to suppress the severe jamming of baseline drift and elimination high-frequency harmonic, be provided with the bandwidth-limited circuit by high-pass filtering circuit and low-pass filter circuit Zhucheng; Undistorted for electrocardiosignal, designed level lifting circuit; In order to eliminate 50 Hz power frequencies, disturb, be provided with 50HZ trap circuit.The present invention by electrocardiosignal is amplified, filtering, level lifting and trap process, and obtained the very high amplifier of gain, performance is good, precision is high, volume is little and energy consumption is lower.
Accompanying drawing explanation
Below in conjunction with accompanying drawing, the invention will be further described:
Fig. 1 is theory diagram of the present invention;
Fig. 2 is the circuit diagram of pre-amplification circuit of the present invention;
Fig. 3 is the circuit diagram of high-pass filtering circuit of the present invention;
Fig. 4 is the circuit diagram of low-pass filter circuit of the present invention;
Fig. 5 is the circuit diagram of level lifting circuit of the present invention;
Fig. 6 is the circuit diagram of 50HZ trap circuit of the present invention.
The specific embodiment
As shown in Figure 1, a kind of ecg signal amplifier of the present invention, it comprises pre-amplification circuit, bandwidth-limited circuit, level lifting circuit and 50HZ trap circuit, described pre-amplification circuit, bandwidth-limited circuit, level lifting circuit and 50HZ trap circuit are connected between core signal sensor and electrocardiosignal processing system after connecting successively, to electrocardiosignal amplify, filtering, level lifting and trap process.
As shown in Figure 2, pre-amplification circuit of the present invention comprises the differential amplifier circuit of both-end input, both-end output, common mode sampling drive circuit, and resaistance-capacity coupling circuit, and both-end is inputted, the differential amplifier circuit of Single-end output; The double input end of the differential amplifier circuit of described both-end input, both-end output is connected with organism contact electrode, and double input end is connected with the double input end of the differential amplifier circuit of both-end input, Single-end output with resaistance-capacity coupling circuit through common mode sampling drive circuit successively.The differential amplifier circuit of described both-end input, both-end output comprises the first operational amplifier U1, the second operational amplifier U2, resistance R 1, resistance R 2 and resistance R 3, described common mode sampling drive circuit comprises the 3rd operational amplifier U3, resistance R 4 and resistance R 5, described resaistance-capacity coupling circuit comprises capacitor C 1, capacitor C 2, resistance R 6 and resistance R 7, and the differential amplifier circuit of described both-end input, Single-end output comprises instrument amplifier A1 and varistor R8; The positive input of described the first operational amplifier U1 and the second operational amplifier U2 is connected with organism contact electrode respectively, series resistance R3 between reverse input end, difference series resistance R1 and resistance R 2 between the reverse input end of the first operational amplifier U1 and the second operational amplifier U2 and outfan; After the outfan series capacitance C1 of described the first operational amplifier U1, be connected with the reverse input end of instrument amplifier A1, after the outfan series capacitance C2 of described the second operational amplifier U2, be connected with the positive input of instrument amplifier A1; The positive input of described the 3rd operational amplifier U3 is connected with the outfan of the second operational amplifier U2 with the first operational amplifier U1 with resistance R 5 through resistance R 4 respectively, inverting input is connected with outfan, and outfan is connected with positive input with the reverse input end of instrument amplifier A1 with resistance R 7 through resistance R 6 respectively; Described varistor R8 is the external gain-adjusted resistance of instrument amplifier A1.Wherein, the first described operational amplifier U1, the second operational amplifier U2 and the 3rd operational amplifier U3 all adopt LM324 integrated circuit, and described instrument amplifier A1 adopts AD620 amplifier.
As shown in Figure 3 and Figure 4, bandwidth-limited circuit of the present invention comprises high-pass filtering circuit and the low-pass filter circuit being connected in series; Described high-pass filtering circuit comprises four-operational amplifier U4, resistance R 9 and capacitor C 3, the positive input of described four-operational amplifier U4 is through resistance R 9 ground connection, through capacitor C 3, be connected with the outfan of pre-amplification circuit, inverting input is connected with outfan simultaneously; Described low-pass filter circuit comprises the 5th operational amplifier U5, resistance R 10, resistance R 11, capacitor C 4 and capacitor C 5, the positive input of described the 5th operational amplifier U5 is through capacitor C 4 ground connection, simultaneously successively series resistance R11 with after resistance R 10 with four-operational amplifier U4 outfan be connected, inverting input is connected with outfan, after the outfan series capacitance C5 of the 5th operational amplifier U5, is connected between resistance R 10 and resistance R 11.Wherein, described four-operational amplifier U4 and the 5th operational amplifier U5 all adopt LM324 integrated circuit.
As shown in Figure 5, level lifting circuit of the present invention comprises the 6th operational amplifier U6, resistance R 12, resistance R 13, resistance R 14, resistance R 15 and adjustable resistance RW1, the positive input of described the 6th operational amplifier U6 is through resistance R 15 ground connection, after inverting input series resistance R12, be connected with the outfan of bandwidth-limited circuit, through resistance R 14, be connected with the adjustable end of adjustable resistance RW1 simultaneously, the two ends of described adjustable resistance RW1 are connected with positive and negative voltage end respectively, series resistance R13 between inverting input and outfan.Wherein, the 6th described operational amplifier U6 adopts LM324 integrated circuit.
As shown in Figure 6,50HZ trap circuit of the present invention comprises the 7th operational amplifier U7, the 8th operational amplifier U8, resistance R 16, resistance R 17, resistance R 18, resistance R 19, resistance R 20, resistance R 21, capacitor C 6, capacitor C 7, capacitor C 8 and capacitor C 9; The positive input of described the 7th operational amplifier U7 is connected with the outfan of level lifting circuit through parallel circuit, described parallel circuit is formed in parallel by the series circuit of the series circuit of resistance R 16, resistance R 17 and capacitor C 6, capacitor C 7, and the inverting input of the 7th operational amplifier U7 is connected with outfan; The positive input of described the 8th operational amplifier U8 is connected with the outfan of the 7th operational amplifier U7 through resistance R 20, pass through resistance R 21 ground connection simultaneously, inverting input is connected with outfan, outfan is connected between capacitor C 6 and capacitor C 7 through the parallel circuit of resistance R 18 and resistance R 19, and the parallel circuit through capacitor C 8 and capacitor C 9 is connected between resistance R 16 and resistance R 17 simultaneously.Wherein, described the 7th operational amplifier U7 and the 8th operational amplifier U8 all adopt LM324 integrated circuit, and described resistance R 16, resistance R 17, resistance R 18, resistance R 19, capacitor C 6, capacitor C 7, capacitor C 8 and capacitor C 9 form a capacitance-resistance twin-T network.
It should be noted that illustrated parts are not necessarily drawn in proportion in the accompanying drawings.The present invention has omitted the description of known assemblies and treatment technology and technique to avoid unnecessarily limiting the present invention.
The above is the preferred embodiment of the present invention, for those skilled in the art, under the premise without departing from the principles of the invention, can also make some improvements and modifications, and these improvements and modifications are also regarded as protection scope of the present invention.

Claims (9)

1. an ecg signal amplifier, it is characterized in that, comprise pre-amplification circuit, bandwidth-limited circuit, level lifting circuit and 50HZ trap circuit, described pre-amplification circuit, bandwidth-limited circuit, level lifting circuit and 50HZ trap circuit are connected between core signal sensor and electrocardiosignal processing system after connecting successively, to electrocardiosignal amplify, filtering, level lifting and trap process; Described pre-amplification circuit comprises the differential amplifier circuit of both-end input, both-end output, common mode sampling drive circuit, and resaistance-capacity coupling circuit, and both-end is inputted, the differential amplifier circuit of Single-end output; The double input end of the differential amplifier circuit of described both-end input, both-end output is connected with organism contact electrode, and double input end is connected with the double input end of the differential amplifier circuit of both-end input, Single-end output with resaistance-capacity coupling circuit through common mode sampling drive circuit successively; Described bandwidth-limited circuit comprises high-pass filtering circuit and low-pass filter circuit, and described high-pass filtering circuit and low-pass filter circuit are connected in series.
2. a kind of ecg signal amplifier according to claim 1, it is characterized in that, the differential amplifier circuit of described both-end input, both-end output comprises the first operational amplifier U1, the second operational amplifier U2, resistance R 1, resistance R 2 and resistance R 3, described common mode sampling drive circuit comprises the 3rd operational amplifier U3, resistance R 4 and resistance R 5, described resaistance-capacity coupling circuit comprises capacitor C 1, capacitor C 2, resistance R 6 and resistance R 7, and the differential amplifier circuit of described both-end input, Single-end output comprises instrument amplifier A1 and varistor R8; The positive input of described the first operational amplifier U1 and the second operational amplifier U2 is connected with organism contact electrode respectively, series resistance R3 between reverse input end, difference series resistance R1 and resistance R 2 between the reverse input end of the first operational amplifier U1 and the second operational amplifier U2 and outfan; After the outfan series capacitance C1 of described the first operational amplifier U1, be connected with the reverse input end of instrument amplifier A1, after the outfan series capacitance C2 of described the second operational amplifier U2, be connected with the positive input of instrument amplifier A1; The positive input of described the 3rd operational amplifier U3 is connected with the outfan of the second operational amplifier U2 with the first operational amplifier U1 with resistance R 5 through resistance R 4 respectively, inverting input is connected with outfan, and outfan is connected with positive input with the reverse input end of instrument amplifier A1 with resistance R 7 through resistance R 6 respectively; Described varistor R8 is the external gain-adjusted resistance of instrument amplifier A1.
3. a kind of ecg signal amplifier according to claim 2, it is characterized in that, the first described operational amplifier U1, the second operational amplifier U2 and the 3rd operational amplifier U3 all adopt LM324 integrated circuit, and described instrument amplifier A1 adopts AD620 amplifier.
4. a kind of ecg signal amplifier according to claim 1, it is characterized in that, described high-pass filtering circuit comprises four-operational amplifier U4, resistance R 9 and capacitor C 3, the positive input of described four-operational amplifier U4 is through resistance R 9 ground connection, through capacitor C 3, be connected with the outfan of pre-amplification circuit, inverting input is connected with outfan simultaneously; Described low-pass filter circuit comprises the 5th operational amplifier U5, resistance R 10, resistance R 11, capacitor C 4 and capacitor C 5, the positive input of described the 5th operational amplifier U5 is through capacitor C 4 ground connection, simultaneously successively series resistance R11 with after resistance R 10 with four-operational amplifier U4 outfan be connected, inverting input is connected with outfan, after the outfan series capacitance C5 of the 5th operational amplifier U5, is connected between resistance R 10 and resistance R 11.
5. a kind of ecg signal amplifier according to claim 4, is characterized in that, described four-operational amplifier U4 and the 5th operational amplifier U5 all adopt LM324 integrated circuit.
6. a kind of ecg signal amplifier according to claim 1, it is characterized in that, described level lifting circuit comprises the 6th operational amplifier U6, resistance R 12, resistance R 13, resistance R 14, resistance R 15 and adjustable resistance RW1, the positive input of described the 6th operational amplifier U6 is through resistance R 15 ground connection, after inverting input series resistance R12, be connected with the outfan of bandwidth-limited circuit, through resistance R 14, be connected with the adjustable end of adjustable resistance RW1 simultaneously, the two ends of described adjustable resistance RW1 respectively with just, negative voltage side connects, series resistance R13 between inverting input and outfan.
7. a kind of ecg signal amplifier according to claim 6, is characterized in that, the 6th described operational amplifier U6 adopts LM324 integrated circuit.
8. a kind of ecg signal amplifier according to claim 1, it is characterized in that, described 50HZ trap circuit comprises the 7th operational amplifier U7, the 8th operational amplifier U8, resistance R 16, resistance R 17, resistance R 18, resistance R 19, resistance R 20, resistance R 21, capacitor C 6, capacitor C 7, capacitor C 8 and capacitor C 9; The positive input of described the 7th operational amplifier U7 is connected with the outfan of level lifting circuit through parallel circuit, described parallel circuit is formed in parallel by the series circuit of the series circuit of resistance R 16, resistance R 17 and capacitor C 6, capacitor C 7, and the inverting input of the 7th operational amplifier U7 is connected with outfan; The positive input of described the 8th operational amplifier U8 is connected with the outfan of the 7th operational amplifier U7 through resistance R 20, pass through resistance R 21 ground connection simultaneously, inverting input is connected with outfan, outfan is connected between capacitor C 6 and capacitor C 7 through the parallel circuit of resistance R 18 and resistance R 19, and the parallel circuit through capacitor C 8 and capacitor C 9 is connected between resistance R 16 and resistance R 17 simultaneously.
9. a kind of ecg signal amplifier according to claim 8, is characterized in that, described the 7th operational amplifier U7 and the 8th operational amplifier U8 all adopt LM324 integrated circuit.
CN201410183288.0A 2014-05-04 2014-05-04 Electrocardiosignal amplifier Pending CN104000576A (en)

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CN104617913A (en) * 2015-02-10 2015-05-13 东南大学 Radio frequency high-Q value band-pass filter
CN106568834A (en) * 2016-11-15 2017-04-19 重庆工商大学 Detection method for changes of internal magnetic field of magneto-rheological damper based on magnetic tunnel junction
CN109026646A (en) * 2018-08-09 2018-12-18 武汉长江科创科技发展有限公司 A kind of chemical grouting pump monitoring system based on Internet of Things
CN109893133A (en) * 2019-04-08 2019-06-18 上海大学 A kind of noninvasive acquisition system of nerve signal
CN113225036A (en) * 2021-05-12 2021-08-06 上海电气集团股份有限公司 Preamplifier and medical piezoelectric film sensor
CN113765490A (en) * 2021-08-17 2021-12-07 上海卫星装备研究所 Pre-amplification circuit for output end of induction synchronizer and induction synchronizer

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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104617913A (en) * 2015-02-10 2015-05-13 东南大学 Radio frequency high-Q value band-pass filter
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CN109026646A (en) * 2018-08-09 2018-12-18 武汉长江科创科技发展有限公司 A kind of chemical grouting pump monitoring system based on Internet of Things
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CN113225036A (en) * 2021-05-12 2021-08-06 上海电气集团股份有限公司 Preamplifier and medical piezoelectric film sensor
CN113765490A (en) * 2021-08-17 2021-12-07 上海卫星装备研究所 Pre-amplification circuit for output end of induction synchronizer and induction synchronizer
CN113765490B (en) * 2021-08-17 2023-11-10 上海卫星装备研究所 Pre-amplifying circuit for output end of induction synchronizer and induction synchronizer

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