Summary of the invention
Technical problem to be solved by this invention is to provide a kind of for improving the feed of laying hen egg yield, and this feed can guarantee pure natural property when improving laying hen egg yield, has no drug resistance, and toxic and side effect is little, and to the later stage, human injury is little.
In order to realize foregoing invention object, the invention provides a kind ofly for improving the feed of laying hen egg yield, described feed comprises following raw material: wheat, wheat bran, dregs of beans, wheat complex enzyme, montmorillonite, cabbage powder, soybean oil, vitamin D and Chinese medicine additive.
Described feed is comprised of the raw material of following parts by weight: wheat 50-70 weight portion, wheat bran 20-30 weight portion, dregs of beans 20-30 weight portion, wheat complex enzyme 5-10 weight portion, montmorillonite 3-8 weight portion, cabbage powder 10-20 weight portion, soybean oil 3-8 weight portion, vitamin D 0.1-1 weight portion and Chinese medicine additive 1-3 weight portion.
Described feed is preferably comprised of the raw material of following parts by weight: wheat 62 weight portions, wheat bran 25 weight portions, dregs of beans 25 weight portions, wheat complex enzyme 7 weight portions, montmorillonite 5 weight portions, cabbage powder 15 weight portions, soybean oil 5 weight portions, vitamin D 0.4 weight portion and Chinese medicine additive 2 weight portions.
Described Chinese medicine additive comprises following raw medicinal material: the Radix Astragali, notopterygium root, wilsonii, safflower, Poria cocos, Divine Comedy, the fruit of Chinese magnoliavine, white fungus, lettuce, glossy ganoderma, purpleflower stonecrop herb, betel nut, Semen Lablab Album, bodhi perfume, the seed of feather cockscomb, rust-coloured crotalaria herb with root, radix bupleuri and date.
In described Chinese medicine additive, the parts by weight of each raw medicinal material are: Radix Astragali 20-30 weight portion, notopterygium root 10-20 weight portion, wilsonii 10-25 weight portion, safflower 10-20 weight portion, Poria cocos 10-20 weight portion, Divine Comedy 10-20 weight portion, fruit of Chinese magnoliavine 10-25 weight portion, white fungus 10-15 weight portion, lettuce 10-20 weight portion, glossy ganoderma 20-30 weight portion, purpleflower stonecrop herb 10-20 weight portion, betel nut 10-15 weight portion, Semen Lablab Album 10-25 weight portion, the fragrant 10-15 weight portion of bodhi, seed of feather cockscomb 10-20 weight portion, rust-coloured crotalaria herb with root 10-25 weight portion, radix bupleuri 10-20 weight portion and date 10-20 weight portion.
In described Chinese medicine additive, the parts by weight of each raw medicinal material are preferably: the Radix Astragali 25 weight portions, notopterygium root 15 weight portions, wilsonii 17 weight portions, safflower 15 weight portions, Poria cocos 15 weight portions, Divine Comedy 15 weight portions, the fruit of Chinese magnoliavine 17 weight portions, white fungus 13 weight portions, lettuce 15 weight portions, glossy ganoderma 25 weight portions, purpleflower stonecrop herb 15 weight portions, betel nut 13 weight portions, Semen Lablab Album 17 weight portions, fragrant 12 weight portions of bodhi, the seed of feather cockscomb 15 weight portions, rust-coloured crotalaria herb with root 17 weight portions, radix bupleuri 15 weight portions and date 15 weight portions.
Described Chinese medicine additive also comprises: spinach fruit, dried human placenta, Chinese yam and bush.
In described Chinese medicine additive, the parts by weight of each raw medicinal material are preferably: Radix Astragali 20-30 weight portion, notopterygium root 10-20 weight portion, wilsonii 10-25 weight portion, safflower 10-20 weight portion, Poria cocos 10-20 weight portion, Divine Comedy 10-20 weight portion, fruit of Chinese magnoliavine 10-25 weight portion, white fungus 10-15 weight portion, lettuce 10-20 weight portion, glossy ganoderma 20-30 weight portion, purpleflower stonecrop herb 10-20 weight portion, betel nut 10-15 weight portion, Semen Lablab Album 10-25 weight portion, the fragrant 10-15 weight portion of bodhi, seed of feather cockscomb 10-20 weight portion, rust-coloured crotalaria herb with root 10-25 weight portion, radix bupleuri 10-20 weight portion, date 10-20 weight portion, spinach fruit 10-20 weight portion, dried human placenta 10-20 weight portion, Chinese yam 10-20 weight portion and bush 10-20 weight portion.
The preparation method of described Chinese medicine additive comprises the following steps:
Step 1, all raw medicinal materials are dropped in mixer in proportion and stir, mix, after send in pulverizer and to pulverize, the Chinese medicine composition after pulverizing is packed in multi-function extractor, add water with respect to 5 ~ 7 times of amounts of its quality, boil 2 ~ 4 hours, steam pressure is that 0.6 ~ 1Mpa processes, filter, obtain the first filtered fluid and filter residue;
Step 2, the filter residue of acquisition is again added to water with respect to 5 ~ 7 times of amounts of its quality, boils 2 ~ 4 hours, steam pressure is that 0.6Mpa ~ 1Mpa processes, and filters and obtains the second filtered fluid and filter residue;
Step 3, the first filtered fluid and the second filtered fluid are merged, concentratedly remove moisture, obtain and get dry extract, adopt super-fine powder mill to pulverize, be crushed to below 30 μ m, obtain Chinese medicine additive powder.
In order better to realize foregoing invention object, it is a kind of for improving the preparation method of the feed of laying hen egg yield that the present invention also provides, and described preparation method comprises the following steps:
(1) broken step: take by weight wheat, wheat bran, dregs of beans, montmorillonite and cabbage powder, drop into pulverizer and carry out Crushing of Ultrafine, cross 2.0mm sieve after pulverizing;
(2) batching step: take vitamin D and Chinese medicine additive according to parts by weight, pulverize the fine powder obtaining mix with step (1), drop into mixer, mix, incorporation time is 30-60s;
(3) granulation step: drop into granulator and granulate, pelleting temperature is 80 ℃, and its gelatinization degree is reached more than 90%, obtains pellet;
(4) spraying step: the surface that by weight wheat complex enzyme is sprayed to pellet.
The beneficial effect that technical scheme provided by the invention is brought is: feed of the present invention contains Chinese medicine additive, the effect that there is tonifying middle-Jiao and Qi, stomach strengthening and digestion promoting and whet the appetite, interact, jointly coordinate with other raw materials, can effectively improve laying hen egg yield, there is again pure natural property, have no drug resistance, toxic and side effect is little, the advantage that the later stage is little to human injury.
The specific embodiment
The invention provides a kind of feed that contains Chinese medicine additive, wherein Chinese medicine additive comprises: the Radix Astragali, notopterygium root, wilsonii, safflower, Poria cocos, Divine Comedy, the fruit of Chinese magnoliavine, white fungus, lettuce, glossy ganoderma, purpleflower stonecrop herb, betel nut, Semen Lablab Album, bodhi perfume, the seed of feather cockscomb, rust-coloured crotalaria herb with root, radix bupleuri and date; Preferably, Chinese medicine additive also comprises: spinach fruit, dried human placenta, Chinese yam and bush.
Wherein, the pharmacological property of each raw medicinal material is:
The Radix Astragali: bitter, cold in nature, the thoughts of returning home, lung, stomach, courage, large intestine channel, have heat-clearing and damp-drying drug, and purging intense heat and detonicating is antiabortive, the effect of hemostasis, the diarrhoea, dysentery, jaundice, the heat that cure mainly due to damp and hot are drenched; Cough with lung heat, thirsty pharyngalgia, also can be used for fetal movement with fever, and hot malicious fire-evil is invaded the swollen card of sore carbuncle poison of excessive skin.
Notopterygium root: return bladder; Kidney channel.Nature and flavor: taste is pungent; Bitter; Warm in nature.Loose exterior cold; Wines used as antirheumatic; Profit joint; Pain relieving.Loose exterior cold, wines used as antirheumatic, sharp joint.The chill that cures cold, has a headache lossless, wind-cold-dampness arthralgia, a strong muscular contracture, joint ache, geomantic omen edema, skin sore.For impotence and seminal emission, enuresis frequent micturition, waist knee crymodynia, suffers from a deficiency of the kidney and breathes heavily, Diarrhoea; External application curing vitiligo, alopecia areata.Induce sweat loose cold, expelling wind and eliminating dampness, pain relieving.Be used for catching cold, fever with aversion to cold, the cards such as headache bodily pain.This product has stronger expelling cold, eliminating and analgesic effect.Often be equal to use with windproof, the root of Dahurain angelica, the root of Chinese wild ginger, as Notoptreygium Decoction of Nine Ingredients.Podomere pain, aching pain in should and back due to attacking for wind-cold damp pathogen, especially more applicable with upper part of the body pain.This product can be dispeled the wind and be won temperature, eliminating cold to stop pain.Often with windproof, same use, as juanbi decoction.< < property of medicine opinion > >: " control harmful wind, aphonia in silence, the blood leprosy of itching, hands and feet caused by paralysis, the askew heresy of actinal surface, stupid numbness all over more." < < Japan hanako materia medica > >: " and control a wind cutting gas, muscles and bones fist contraction, four limbs are thin bad, head revolves the red pain of eyes and mass located in the upper or lower abdomen aqueous vapor, general debility, deficient cold air, joint ache, tonneau the five internal organs." < < pearl sac > >: " Taiyang channel headache, removes all arthralgias, also can warm courage." the smart > > that wants of < < product remittance: " main all joints being painful all over, flesh table Bafeng thief is evil, removes new and old rheumatism, arranges slough subcutaneous ulcer sore." < < Essentials of Materia Medica > >: " purging the liver of pathogenic fire gas, searches liver wind, controls evils of wind and weness blended to attack the body, herbal classic (sun) headache, governor vessel is disease, back rigidity and fainting, the soft convulsion of tonic convulsion, aphasia from apoplexy, head revolves hot eyes." < < can approximately cure mirror > >: " control heresy and close the loathing of cold, high fever is lossless.”
Wilsonii: pungent, the micro-hardship of taste, slightly warm in nature.Return spleen, kidney, the heart channel of Hang-Shaoyin.Modern medicine studies have shown that effect feature and the ginseng of wilsonii is basic identical, has the body of adjusting disorderly, makes it to be tending towards normal function.There is good antifatigue effect, remarkable compared with ginseng, and can significantly improve hypoxia-bearing capability.Bowl spares, benefit essence, strong will, wines used as antirheumatic, strengthen the bone, the function such as blood circulation and promoting silt, stomach invigorating diuresis.Take for a long time " make light of one's life by commiting suicide and endure hardships ".Wilsonii contains noticeable composition---eleutheroside, and it can stimulate mind & body vigor.Numerous scientific publications about wilsonii have proved its antifatigue effect, strengthen endurance and ability, increase alertness and learning ability.Numerous usages have all obtained confirmation in human experimentation.Wilsonii is rehabilitation after being ill, bears too much pressure or anxiety, works excessive, and chronic disease causes weakly crowd and those need to reach very welcome self-medication medicine in the people on physiology and psychological performance peak.At present there is equally the report of considerable quantity to point out that it has support immune system, recover improper low blood pressure, improve the circulatory system, make disorderly glycolipid metabolism normalization, liver, testis, the anabolic effect of bone density and other vitals.Siberian Ginseng P.E shows can irritation cell immunity.Research finds that it can stimulate T-cell to produce, particularly assistant's cell.Therefore wilsonii is used to panimmunity relevant disease.Radix Et Caulis Acanthopanacis Senticosi polysaccharide also has strong inhibitory action to the in-vitro multiplication of mouse S180, human leukaemia K562 cell, and siberian Ginseng P.E is containing multiple glucoside and Radix Et Caulis Acanthopanacis Senticosi polysaccharide, have improve immunity of organisms, increasing leukocyte, raising body to anoxic, radiation, stress, the adaptive capacity of the non-specific injury such as tired, poisoning.Tumour is had to obvious inhibitory action, also can promote marrow hemopoietic stem cells to the differentiation of grain-monocyte, leucocyte to be increased simultaneously.
Safflower: the effect to cardiovascular system: safflower decoction low dose can make toad isolated heart and rabbit in slightly excitement of systemic heart, makes heartbeat strong, and amplitude strengthens; Heavy dose has inhibitory action to heart, makes decreased heart rate, and myocardial contractive power weakens, and cardiac output reduces.Crude extract from carthamus tinctorius L. with water and safflower water soluble mixt-carthamin yellow have the effect that increases CF and Nutritional myocardium blood flow amount; The coronary artery dilating of safflower ethanol extract and the effect that increases CF are not obvious or without impact.Rabbit, rat, dog etc., cause on the animal model of expeirmental myocardial ischemia or miocardial infarction, safflower and preparation thereof all have antagonism in various degree.Safflower can make the rat or the Rabbits With Acute Myocardial Ischemia that because of pituitrin, cause have obvious protective effect; Can make Repeated Brief blocking-up coronary flow cause the degree of anesthetized dog acute myocardial ischemia obviously to alleviate; scope is dwindled; decreased heart rate; and protect the edge in acute myocardial infarction district; district and dwindle infarction size and reduce the amplitude that marginal zone ECG ST section is raised, thus the supply-demand relationship of ischemic myocardium oxygen improved.As first, with the Rockwell liquid perfusion blood vessel containing micro-adrenaline or norepinephrine, make animal myocardium vessel smooth muscle contraction keep certain vascular tone, cause may similar people obstructed, the state of blood stasis of blood vessels.Safflower can make cavy hind leg and the rabbit ear that tonicity increases present vasorelaxation action, and increases and act on obviously with dosage, and safflower also can increase anesthetized dog FABF, but can make it to shrink to the normal myocardium vessel of toad and rabbit.Show that the effect of safflower hemangiectasis is relevant with the dosage of medicine with the functional status of blood vessel.Its mechanism of action may be mainly directly or partly resist the effect of a-adrenergic receptor and distend the blood vessels, and has weak direct vasoconstriction effect.Safflower decoction, carthamin yellow and other preparations all have rapid depressurization effect in various degree to anesthetized cat or dog, and mean blood pressure declines about 20 mm Hg, continue to recover after approximately 30 minutes.Carthamin yellow has the Platelet Aggregation in Rabbits effect that suppresses very significantly ADP induction, and the blood platelet that ADP has been assembled also has very significantly depolymerisation.When dosage is 0.22g/ml, assembles inhibiting rate and depolymerization percentage and reach respectively 85.9% and 78.9%.These effects of carthamin yellow, strengthen along with the increase of dosage.Carthamin yellow, to rat experiment thrombosis, has the depression effect of highly significant, and its inhibiting rate is 73.4%.Because experiment adopts the thrombus material base forming on silk thread, be platelet aggregation thing, so the alleviating of wet weight of thrombus, be obviously the result that medicine suppresses platelet aggregation.It is consistent that the carthamin yellow confirming with experiment in vitro can suppress the platelet aggregation that ADP causes.Carthamin yellow still can obviously extend plasma in rabbit recalcification time, prothrombin time and clotting time.Show that it can affect in body and external blood coagulation system simultaneously.In addition, safflower oil has reduction blood fat.Impact on the resistance to anoxic of animal: antifatigue effect, relatively, swimming time obviously extends for carthamin yellow 1100mg/kg mouse and control group (using equivalent physiological saline), and rate elongation reaches 117.O%, P<0.01.; Ip in mice ll00mg/kg carthamin yellow, compare with control group (waiting capacity physiological saline), in administration, after 30 minutes, every mouse is put into respectively the airtight vial of 125ml that fills 15g soda lime, experimental group extends the time-to-live 48.8%, P<0.01.Impact on mouse hypobaric hypoxia endurance: the administration of the same method mouse, after 30 minutes, puts into respectively by mouse the storehouse that volume is equal, the airtight negative pressure 450mmHg that is decompressed to, observes 60 minutes.Result and control group comparison, survival rate (%) 15:10, administration group extends the time-to-live 168.72%, P<0.001.Effect to uterus: safflower decoction all has excitation to the isolated uterine of mouse, cavy, rabbit and dog.Anesthetized animal is tested and is shown, decoction iv also has excitation to the uterus in place of mouse, cat and dog.No matter in vitro or after being positioned at palace administration tonicity or (with) rhythmicity obviously increases, excitation is sometimes strong, can cause spasm.More more obvious than unpregnancy person to the effect in pregnant uterus.After fistula of uterus rabbit iv decoction, also occur uteri excitation reaction, contraction frequency increases, and amplitude strengthens, and it is more lasting to act on.Also have report, the vagina surrounding injection safflower decoction extracing ovary mouse, can make uterus weight obviously increase, and prompting has estrogen-like action.Analgesia and sedation: get 40 of mouse, divide 4 groups.Respectively ip carthamin yellow 550mg/kg, 1100mg/kg, morphine hydrochloride 20mg/kg and etc. capacity physiological saline.Ip0.7% glacial acetic acid 0.1ml/10g after 30 minutes.Observe every mouse writhing number of times in 20 minutes, with control group comparison, calculate mouse writhing reaction inhibiting rate.The carthamin yellow of two kinds of dosage of result all can obviously suppress mouse writhing reaction, the equal <0.001 of P.With the mouse of the group of above-mentioned two kinds of dosage, each treated animal ip barbital sodium subthreshold hypnotic dosage 300mg/kg or chloraldurate subthreshold hypnotic dosage 250mg/kg after 30 minutes.Observe righting reflex loss in 30 minutes and reach l minute above number of mice, calculate each treated animal rate of falling asleep.Result shows, is all waking state to the control-animal of barbital sodium sub-threshold dose, and share with carthamin yellow, and heavy dose of rate of falling asleep improves 40%, heavy dose of 70%(P<0.01 that improves); Two kinds of dosage can make chloraldurate sub-threshold dose fall asleep rate by 20%, improve respectively 50% and 80%(P<0.01), prompting carthamin yellow has the central inhibitory action of obvious enhancing barbital and chloraldurate, its effect becomes parallel relation with consumption.Antiinflammatory action: the foot swelling of carthamin yellow PARA FORMALDEHYDE PRILLS(91,95) has obvious inhibitory action.Impact on rat capillary permeability: the penetrating amount increase of the rat skin capillary that histamine is caused has obvious inhibitory action.Immunocompetence: safflower polysaccharide is different from the polysaccharide that in higher plant, a-key connects, is similar to the polysaccharide of bacterial origin.From external pouring, turn experiment and show, safflower polysaccharide and the former ConA of T cell mitogenesis have synergy, to former the having no significant effect of B cell mitogenesis.But PFC test in body, safflower polysaccharide with it is generally acknowledged that to act on the astragalus polyose effect trend of B cell consistent.Give the asynchronism(-nization) of injected in mice safflower polysaccharide, the variation of mouse PFC value is also different: after sensitization, the PFC of administration group is promoted, and before sensitization, the PFC of administration group is anti-suppressed.Show that safflower polysaccharide has shown the amphicheirality of immune drug equally.Safflower polysaccharide can obviously resist the immunosuppressive action of prednisolone, and the immunological enhancement that it suppresses mouse to prednisolone is more obvious to the effect of normal mouse.Therefore, safflower polysaccharide can promote to drench cell transformation, increases the cell number of splenocyte to sheep red blood cell plaque test, and the immunosuppressive action of antagonism prednisolone etc., show that it is a kind of new, worth further immunomodulator of research.Another Safflor yellow (SY) reduces serum lysozyme content, peritoneal macrophage and whole blood phagocytic activity of leukocytes; PFC, SRFC and antibody are produced to be reduced; Suppress the Ts cell activation of DH reaction and SOI induction, external, SY0.03-3.0, generation and the activity thereof of the T that 0.1-2.O and 0.1-2.5mg/ml inhibition TdR mix, bone-marrow-derived lymphocyte conversion, MLC reaction, IL2.
Poria cocos: sweet, light, flat.The thoughts of returning home, lung, spleen, kidney channel.Function clearing damp and promoting diuresis, the peaceful heart of invigorating the spleen.For oedema oliguria, phlegm and retained fluid is dizzy throbs with fear, and insufficiency of the spleen food is few, and have loose bowels in loose stool, confused and worried, palpitation with fear insomnia.Eliminating dampness and diuresis, beneficial spleen and stomach, antitoxic heart-soothing and sedative.Control difficult urination, oedema turgor, phlegm and retained fluid is coughed contrary, and the sound of vomiting of vomitting, has loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful.< < herbal classic > > carries it: " the contrary gas of the main chest side of body, sorrow is angerd frightened heresy and is probably throbbed with fear, knot pain under the heart, fever and chills dysphoria, coughs contraryly, and mouthful burnt tongue is dry, diuresis." < < do not record > >: " and only quench one's thirst, like to sleep, large abdomen, drenches drop, phlegm water in diaphragm, and oedema is drenched knot.Open chest internal organs, adjust visceral-qi, cut down kidney heresy, long cloudy, beneficial strength, during guarantor god keeps." < < property of medicine opinion > >: " appetizing, preventing or arresting vomiting is contrary, kind tranquilizing mind.Main consumptive lung disease phlegm is stopped up.Control pediatric epilepsy scared, trusted subordinate's turgor, married woman's heat is drenched.”
Divine Comedy: cure mainly dyspepsia, rush down dysentery etc.The Northern Wei Dynasty, Jia Si peaceful < < Qimin yaoshu was made refreshing Qu wine > >: " make refreshing Qu milled glutinous broomcorn millet wine side: smooth file Qu, dryly exposes to the sun it.Qu is a pipeful of, water nine buckets, meter San Shi.Must many authors, rate with this in addition, its urn size ear of leting people." Ming Dynasty Li Shizhen (1518-1593 A.D.) < < Compendium of Materia Medica paddy four refreshing Qu > >: " former times people Qu, mostly be the Qu brewing alcoholic beverages, rear doctor makes refreshing Qu, specially for medicine, power more wins it, lid is got the day of all god party and is made it, therefore obtain tetragrammaton ".
The fruit of Chinese magnoliavine: temperature; Sour, sweet; Return lung, the heart, kidney channel.Restrain astringent or styptic treatment for spontaneous sweating, nourishing generate fluid, kidney calming.For the void of coughing for a long time, breathe heavily, emission, enuresis frequent micturition, endless diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, the feeble pulse of losing heart, interior heat is quenched one's thirst, palpitation and insomnia.Fruit is made Chinese medicine function nourishing generate fluid, the nourshing kidney of astringing the lung, antidiarrheal, puckery essence, is calmed the nerves, and can control the diseases such as chronic cough void is breathed heavily, dry is lacked in Tianjin, seminal emission is rushed down for a long time, forgetful insomnia.Pharmacological testing proof can regulate excitement and the process of inhibition of central nervous system, promotes body metabolism, regulates gastric juice and bile secretion, and to hepatitis convalescence transaminase, rising person has reducing effect.
White fungus: sweet; Light; Flat; Nontoxic.Return lung; Stomach; Kidney channel.Function cures mainly: nourishing is promoted the production of body fluid; Moistening lung nourishing the stomach.Main cough due to consumptive disease; Blood-stained sputum; Tianjin is few thirsty; Body is empty after being ill; Shortness of breath and fatigue.
Lettuce: bitter; Sweet; Cool in nature.Return stomach; Small intestinl channel.Function cures mainly: diuresis; Logical breast; Clearing heat and detoxicating.Main difficult urination; Hematuria; Alactation; Worm snake bite; Pyogenic infections.
Glossy ganoderma: property is sweet, flat.The thoughts of returning home, lung, liver, kidney channel.Cure mainly consumptive disease, cough, asthma, insomnia, indigestion, malignant tumour etc.Animal pharmacology shows experiment: glossy ganoderma has inhibitory action to nervous system, and the circulatory system has step-down and strengthens the effect of cardiac contractile force, and respiratory system is had to phlegm-dispelling functions, in addition, protects in addition liver, improves immunologic function, antibacterially waits effect.
Purpleflower stonecrop herb: bitter; Cool in nature.Function cures mainly: promoting blood circulation and hemostasis; Clearing heat and detoxicating.Main haematemesis; Dampen; Lumbar muscle strain; Scald; Venomous snake bite; Herpes zoster; Indigestion.
Betel nut: bitter; Pungent; Warm in nature.Return stomach; Large intestine channel.Effect, expelling parasite; Disappear long-pending; Lower gas; Row water; Preventing malaria.Malnutrition due to parasitic infestation; Eat stagnant; Abdominal distention; After rushing down dysentery, weigh; Beriberi; Oedema; Malaria.Resisting pathogenic microbes effect betel nut infusion (1:1) in vitro to trichophyton, permitted the dermatophytes such as blue achorion and had inhibitory action in various degree.Decoction and some strain of water logging agent infected by influenza A type have certain inhibitory action, and antiviral effect may be relevant with wherein contained tannin.
Semen Lablab Album: taste is sweet, slightly warm in nature, enters spleen, stomach warp, have invigorating the spleen for eliminating dampness and in the effect of relieving summer heat, for weakness of the spleen and the stomach indigestion and loss of appetite abdominal distension, loose stool, diarrhea with undigested food, the card such as contrary of vomitting of feeling sick.
Bodhi is fragrant: pungent, sweet, flat.Function cures mainly: enriching yin and nourishing kidney, flat liver improving eyesight, swelling and pain relieving.Cure cold, dizziness headache, hypertension, anaemia, chronic enterogastritis, irregular menstruation, mastitis, the diseases such as sore.
The seed of feather cockscomb: hardship, is slightly cold.Return Liver Channel.Function cures mainly: clearing liver, improving eyesight, moves back screen.For the hot hot eyes of liver, the screen of looking unfamiliar film, blurring of vision, hepatopyretic vertigo.
Rust-coloured crotalaria herb with root: bitter micro-acid, cold.Enter lung.Function cures mainly: the gas of astringing the lung, tonifying spleen kidney, diuresis, detumescence poison.Control chronic cough phlegm blood, tinnitus, deafness, nocturnal emission, chronic nephritis, cystitis, kidney stone, tonsillitis, adenolymphitis, serious case of furuncle, dislikes sore.
Radix bupleuri: clearind deficient heat Chinese medicine, for cold, fever, fevers and chills alternate, malaria, stagnation of QI due to depression of the liver, sternal rib pain, prolapse of the anus, uterus come off, irregular menstruation.Radix bupleuri begins to be loaded in < < Sheng Nong's herbal classic > >, classifies as top grade.Promote immunity function, active ingredient: Bupleurum chinense polysaccharide.Effect: phagocytic function strengthens, Natural killer activity strengthens, and improves special viral antibody titre, improves lymphocyte and turns core rate, improves skin delayed hypersensitivity reaction.Anti-liver injury, Bupleurum injection (concentration 1: a 1) 1 ml/ hypodermic injection can significantly reduce the rat blood serum GPT rising that carbon tetrachloride causes for continuous 5 days, degeneration of liver cells and necrosis also obviously alleviate, and in liver cell, glycogen and rna content also approach normal.
Date: taste is sweet, warm in nature, enter spleen, stomach warp, there is the effect of air making-up and spleen enlivening, nourishing blood and tranquilization, harmonizing yingfen and weifen, the mitigation property of medicine, for weakness of the spleen and the stomach, fatigue and asthenia, anorexia and loose stool, the card such as insufficiency of vital energy and blood, has a headache and fever, sweating hot blast.
Spinach fruit: slightly warm in nature, taste is micro-pungent sweet.Return spleen, lung two warps.Function cures mainly: dispelling pathogenic wind for improving eyesight, open orifice opening, sharp stomach.
Dried human placenta: sweet, salty, temperature.The thoughts of returning home, lung, kidney channel.Function cures mainly: warm kidney is mended essence, nourishing qi and blood.Thin thin for consumptive disease, hectic fever due to yin night sweat, cough and asthma, food weak breath is short, impotence and seminal emission, infertile few breast.
Chinese yam: taste is sweet, property is flat, enters lung, spleen, kidney channel; Not dry oiliness, have and strengthening the spleen and tonifying the lung, beneficial stomach kidney tonifying, the benefit of reinforcing the kidney essence, hearing-improing and eyesight improving, help the five internal organs, strengthening the bones and muscles, grow the effect that will is calmed the nerves, promoted longevity; Cure mainly that weakness of the spleen and the stomach, lassitude, poor appetite, chronic diarrhea and dysentery, Lung Qi deficiency are dry, asthma due to excessive phlegm cough, kidney qi loss, soreness and weakness of waist and knees, lower limb impotence are weak, the red illness such as swollen, fat of the frequent micturition of quenching one's thirst, seminal emission premature ejaculation, the lower gonorrhoea of band, skin.< < Compendium of Materia Medica > > summarizes five large functions " kidney-nourishing gas, strengthening the spleen and stomach, stopping leak dysentery, the saliva that reduces phlegm, profit skin ".Chinese yam is cooked congee or simmers after ripe and take with rock sugar, and, colitis poor to health, deficiency of the kidney chronic diseases are all effective in cure.Strengthen the spleen and stomach: treat weakness of the spleen and the stomach, have loose bowels, body is tired, food less, abnormal sweating.Benefit lung nourshing kidney: this product is cold not dry, taste Gan Zhirun, can treat lung suffer from a deficiency of the kidney damage quench one's thirst, pass out semen, be with inferior disease.Be described as angle's medicine.
Bush: sweet, salty, flat.The thoughts of returning home, liver, the spleen channel.Function cures mainly: row blood and dissolving stasis, swelling and pain relieving.For through closing dysmenorrhoea, postpartum stasis blocking, chest ventral spine pain, wound swells and ache.
Wherein, feed is preferably comprised of the raw material of following parts by weight: wheat 50-70 weight portion, wheat bran 20-30 weight portion, dregs of beans 20-30 weight portion, wheat complex enzyme 5-10 weight portion, montmorillonite 3-8 weight portion, cabbage powder 10-20 weight portion, soybean oil 3-8 weight portion, vitamin D 0.1-1 weight portion and Chinese medicine additive 1-3 weight portion.
Described feed is preferably comprised of the raw material of following parts by weight: wheat 62 weight portions, wheat bran 25 weight portions, dregs of beans 25 weight portions, wheat complex enzyme 7 weight portions, montmorillonite 5 weight portions, cabbage powder 15 weight portions, soybean oil 5 weight portions, vitamin D 0.4 weight portion and Chinese medicine additive 2 weight portions.
Described Chinese medicine additive comprises following raw medicinal material: the Radix Astragali, notopterygium root, wilsonii, safflower, Poria cocos, Divine Comedy, the fruit of Chinese magnoliavine, white fungus, lettuce, glossy ganoderma, purpleflower stonecrop herb, betel nut, Semen Lablab Album, bodhi perfume, the seed of feather cockscomb, rust-coloured crotalaria herb with root, radix bupleuri and date.
In described Chinese medicine additive, the parts by weight of each raw medicinal material are: Radix Astragali 20-30 weight portion, notopterygium root 10-20 weight portion, wilsonii 10-25 weight portion, safflower 10-20 weight portion, Poria cocos 10-20 weight portion, Divine Comedy 10-20 weight portion, fruit of Chinese magnoliavine 10-25 weight portion, white fungus 10-15 weight portion, lettuce 10-20 weight portion, glossy ganoderma 20-30 weight portion, purpleflower stonecrop herb 10-20 weight portion, betel nut 10-15 weight portion, Semen Lablab Album 10-25 weight portion, the fragrant 10-15 weight portion of bodhi, seed of feather cockscomb 10-20 weight portion, rust-coloured crotalaria herb with root 10-25 weight portion, radix bupleuri 10-20 weight portion and date 10-20 weight portion.
In described Chinese medicine additive, the parts by weight of each raw medicinal material are preferably: the Radix Astragali 25 weight portions, notopterygium root 15 weight portions, wilsonii 17 weight portions, safflower 15 weight portions, Poria cocos 15 weight portions, Divine Comedy 15 weight portions, the fruit of Chinese magnoliavine 17 weight portions, white fungus 13 weight portions, lettuce 15 weight portions, glossy ganoderma 25 weight portions, purpleflower stonecrop herb 15 weight portions, betel nut 13 weight portions, Semen Lablab Album 17 weight portions, fragrant 12 weight portions of bodhi, the seed of feather cockscomb 15 weight portions, rust-coloured crotalaria herb with root 17 weight portions, radix bupleuri 15 weight portions and date 15 weight portions.
Described Chinese medicine additive also comprises: spinach fruit, dried human placenta, Chinese yam and bush.
In described Chinese medicine additive, the parts by weight of each raw medicinal material are preferably: Radix Astragali 20-30 weight portion, notopterygium root 10-20 weight portion, wilsonii 10-25 weight portion, safflower 10-20 weight portion, Poria cocos 10-20 weight portion, Divine Comedy 10-20 weight portion, fruit of Chinese magnoliavine 10-25 weight portion, white fungus 10-15 weight portion, lettuce 10-20 weight portion, glossy ganoderma 20-30 weight portion, purpleflower stonecrop herb 10-20 weight portion, betel nut 10-15 weight portion, Semen Lablab Album 10-25 weight portion, the fragrant 10-15 weight portion of bodhi, seed of feather cockscomb 10-20 weight portion, rust-coloured crotalaria herb with root 10-25 weight portion, radix bupleuri 10-20 weight portion, date 10-20 weight portion, spinach fruit 10-20 weight portion, dried human placenta 10-20 weight portion, Chinese yam 10-20 weight portion and bush 10-20 weight portion.
The preparation method of Chinese medicine additive comprises the following steps:
Step 1, all raw medicinal materials are dropped in mixer in proportion and stir, mix, after send in pulverizer and to pulverize, the Chinese medicine composition after pulverizing is packed in multi-function extractor, add water with respect to 5 ~ 7 times of amounts of its quality, boil 2 ~ 4 hours, steam pressure is that 0.6 ~ 1Mpa processes, filter, obtain the first filtered fluid and filter residue;
Step 2, the filter residue of acquisition is again added to water with respect to 5 ~ 7 times of amounts of its quality, boils 2 ~ 4 hours, steam pressure is that 0.6Mpa ~ 1Mpa processes, and filters and obtains the second filtered fluid and filter residue;
Step 3, the first filtered fluid and the second filtered fluid are merged, concentratedly remove moisture, obtain and get dry extract, adopt super-fine powder mill to pulverize, be crushed to below 30 μ m, obtain Chinese medicine additive powder.
Described preparation method comprises the following steps:
(1) broken step: take by weight wheat, wheat bran, dregs of beans, montmorillonite and cabbage powder, drop into pulverizer and carry out Crushing of Ultrafine, cross 2.0mm sieve after pulverizing;
(2) batching step: take vitamin D and Chinese medicine additive according to parts by weight, pulverize the fine powder obtaining mix with step (1), drop into mixer, mix, incorporation time is 30-60s;
(3) granulation step: drop into granulator and granulate, pelleting temperature is 80 ℃, and its gelatinization degree is reached more than 90%, obtains pellet;
(4) spraying step: the surface that by weight wheat complex enzyme is sprayed to pellet.
Embodiment 1 feed 1
It is a kind of for improving the feed of laying hen egg yield that the embodiment of the present invention provides, and in feed, the parts by weight of each raw material are: wheat 70 weight portions, wheat bran 20 weight portions, dregs of beans 20 weight portions, wheat complex enzyme 9 weight portions, montmorillonite 7 weight portions, cabbage powder 20 weight portions, soybean oil 5 weight portions, vitamin D 0.3 weight portion and Chinese medicine additive 2 weight portions.
Wherein, in Chinese medicine additive, the parts by weight of each raw medicinal material are: the Radix Astragali 25 weight portions, notopterygium root 15 weight portions, wilsonii 17 weight portions, safflower 15 weight portions, Poria cocos 15 weight portions, Divine Comedy 15 weight portions, the fruit of Chinese magnoliavine 17 weight portions, white fungus 13 weight portions, lettuce 15 weight portions, glossy ganoderma 25 weight portions, purpleflower stonecrop herb 15 weight portions, betel nut 13 weight portions, Semen Lablab Album 17 weight portions, fragrant 12 weight portions of bodhi, the seed of feather cockscomb 15 weight portions, rust-coloured crotalaria herb with root 17 weight portions, radix bupleuri 15 weight portions and date 15 weight portions.
The preparation method of Chinese medicine additive comprises the following steps:
Step 1, all raw medicinal materials are dropped in mixer in proportion and stir, mix, after send in pulverizer and to pulverize, the Chinese medicine composition after pulverizing is packed in multi-function extractor, add water with respect to 6 times of amounts of its quality, boil 2 hours, steam pressure is that 0.8Mpa processes, filter, obtain the first filtered fluid and filter residue;
Step 2, the filter residue of acquisition is again added to water with respect to 6 times of amounts of its quality, boils 3 hours, steam pressure is that 0.8Mpa processes, and filters and obtains the second filtered fluid and filter residue;
Step 3, the first filtered fluid and the second filtered fluid are merged, concentratedly remove moisture, obtain and get dry extract, adopt super-fine powder mill to pulverize, be crushed to below 30 μ m, obtain Chinese medicine additive powder.
It is a kind of for improving the preparation method of the feed of laying hen egg yield that the embodiment of the present invention also provides, and comprises the following steps:
(1) broken step: take by weight wheat, wheat bran, dregs of beans, montmorillonite and cabbage powder, drop into pulverizer and carry out Crushing of Ultrafine, cross 2.0mm sieve after pulverizing;
(2) batching step: take vitamin D and Chinese medicine additive according to parts by weight, pulverize the fine powder obtaining mix with step (1), drop into mixer, mix, incorporation time is 50s;
(3) granulation step: drop into granulator and granulate, pelleting temperature is 80 ℃, and its gelatinization degree is reached more than 90%, obtains pellet;
(4) spraying step: the surface that by weight wheat complex enzyme is sprayed to pellet.
Embodiment 2 feeds 2
It is a kind of for improving the feed of laying hen egg yield that the embodiment of the present invention provides, and in feed, the parts by weight of each raw material are: wheat 62 weight portions, wheat bran 25 weight portions, dregs of beans 25 weight portions, wheat complex enzyme 7 weight portions, montmorillonite 5 weight portions, cabbage powder 15 weight portions, soybean oil 4 weight portions, vitamin D 0.4 weight portion and Chinese medicine additive 2 weight portions.
Wherein, in Chinese medicine additive, the parts by weight of each raw medicinal material are: the Radix Astragali 25 weight portions, notopterygium root 15 weight portions, wilsonii 17 weight portions, safflower 15 weight portions, Poria cocos 15 weight portions, Divine Comedy 15 weight portions, the fruit of Chinese magnoliavine 17 weight portions, white fungus 13 weight portions, lettuce 15 weight portions, glossy ganoderma 25 weight portions, purpleflower stonecrop herb 15 weight portions, betel nut 13 weight portions, Semen Lablab Album 17 weight portions, fragrant 12 weight portions of bodhi, the seed of feather cockscomb 15 weight portions, rust-coloured crotalaria herb with root 17 weight portions, radix bupleuri 15 weight portions, date 15 weight portions, spinach fruit 15 weight portions, dried human placenta 15 weight portions, Chinese yam 18 weight portions and bush 13 weight portions.
The preparation method of Chinese medicine additive comprises the following steps:
Step 1, all raw medicinal materials are dropped in mixer in proportion and stir, mix, after send in pulverizer and to pulverize, the Chinese medicine composition after pulverizing is packed in multi-function extractor, add water with respect to 6 times of amounts of its quality, boil 3 hours, steam pressure is that 0.8Mpa processes, filter, obtain the first filtered fluid and filter residue;
Step 2, the filter residue of acquisition is again added to water with respect to 6 times of amounts of its quality, boils 3 hours, steam pressure is that 0.7Mpa processes, and filters and obtains the second filtered fluid and filter residue;
Step 3, the first filtered fluid and the second filtered fluid are merged, concentratedly remove moisture, obtain and get dry extract, adopt super-fine powder mill to pulverize, be crushed to below 30 μ m, obtain Chinese medicine additive powder.
It is a kind of for improving the preparation method of the feed of laying hen egg yield that the embodiment of the present invention also provides, and described preparation method comprises the following steps:
(1) broken step: take by weight wheat, wheat bran, dregs of beans, montmorillonite and cabbage powder, drop into pulverizer and carry out Crushing of Ultrafine, cross 2.0mm sieve after pulverizing;
(2) batching step: take vitamin D and Chinese medicine additive according to parts by weight, pulverize the fine powder obtaining mix with step (1), drop into mixer, mix, incorporation time is 50s;
(3) granulation step: drop into granulator and granulate, pelleting temperature is 80 ℃, and its gelatinization degree is reached more than 90%, obtains pellet;
(4) spraying step: the surface that by weight wheat complex enzyme is sprayed to pellet.
Toxicity test
1, cumulative toxicity test report
Select 20 healthy mices, female, male each 10, the Chinese medicine additive of the embodiment of the present invention 1 of take is object, it is first phase that dosage designs every 5 days, each issue dosage is respectively 0.10LD50,0.15LD50,0.22LD50,0.34LD 50,0.50LD50, and the LD 50 female, male mice of this sample is 5000m part/k part BW (five dosage be 500,750,1100,1700,2500m part/k part BW).Within every 5 days, weigh once, adjust dosage, by 0.1ml/10 part BW per os gavage.After 20 days, animal occurs without death condition, off-test, and by ascending-dose, to tested material after 20 days, female, buck all occurs without death condition.The Chinese medicine additive of embodiment 2 of take is object, carries out according to the method described above toxicity test, and result is as identical in embodiment 1.
2, acute toxicity test
40 of application NIH mouse, SPF level, male and female half and half, body weight 16~20g, carries out acute toxicity test.Mouse is divided into two groups at random, and 20 every group, control group and administration group, test front fasting 12 hours; The Chinese medicine additive of embodiments of the invention 1 preparation is dissolved in water, (concentration is 6.58g crude drug/ml, maximum concentration) gavage, gavage volume is that 5ml/kg(is that single-dose dosage is 32.9 crude drugs/kg), control group gives equivalent physiological saline, administration in a day 2 times, delivery time 6 hours, after administration, Continuous Observation is 14 days, and records toxic reaction and the death toll of mouse.Experimental result shows: with control group comparison, after administration, mouse has no notable difference, experiment Continuous Observation 14 days, and mouse overall health of patients, diet, drinking-water, body weight gain are all normal.Therefore the acute toxicity of the Chinese medicine additive of the embodiment of the present invention 1 is low, clinical drug safety.The Chinese medicine additive of embodiment 2 of take is object, carries out according to the method described above toxicity test, and result is as identical in embodiment 1.
Contrast test
(1) animal used as test
1200 of the Luo Man laying hens in 4 week age, purchased from Shandong Province's chicken house.
(2) experiment grouping
1200 laying hens are divided into three groups at random, 400 every group, be respectively embodiment group 1, embodiment group 2 and control group, all continuously feeding feed, respectively organize free choice feeding and drinking-water.Marek's disease, newcastle disease, infectious bronchitis of chicken, Bursal Disease, infectious laryngotracheitis of chicken, chicken pox, chicken EHEC disease are pressed to immune programme for children routine immunization, in strict accordance with < < pollution-free food layer breeding management guideline > > (NY/ T5043-2001), carry out feeding and management.
(3) test method
Three experimental group take different feeds to feed, and wherein, embodiment group 1 is: the feed 1 of embodiment 1; Embodiment group 2 is: the feed 2 of embodiment 2; Control group is: conventional feed.
Wherein, conventional feed forms by the raw material of following parts by weight: 3.1 parts of 501 parts of corns, 100 parts of wheats, 250 parts of dregs of beans, 13.6 parts, soya-bean oil, 13.3 parts of stone flours, 16 parts of calcium monohydrogen phosphates and salt.
(4) test of egg laying performance
From on-test, feed to 43 week age, every day, egg number, average egg weight, feed intake respectively organized in record, calculates laying rate, feedstuff-egg ratio.
Test data is used SPSS 13. 0 softwares to carry out statistical analysis with mean one-dimensional variance analysis (one-way ANOVA) and chi-square criterion (Chitest).
(5) egg laying performance result is as shown in table 1.
Table 1 is respectively organized the index tables of comparisons such as laying rate of laying hen
From the data of table 1, can find out, adopt feed of the present invention existing for conventional feed, there is the advantage that can increase egg size, improve laying rate and reduction feedstuff-egg ratio.
The foregoing is only preferred embodiment of the present invention, in order to limit the present invention, within the spirit and principles in the present invention not all, any modification of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.