CN103990095A - Traditional Chinese medicinal prescription for treating upper respiratory infection - Google Patents

Traditional Chinese medicinal prescription for treating upper respiratory infection Download PDF

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Publication number
CN103990095A
CN103990095A CN201410233312.7A CN201410233312A CN103990095A CN 103990095 A CN103990095 A CN 103990095A CN 201410233312 A CN201410233312 A CN 201410233312A CN 103990095 A CN103990095 A CN 103990095A
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chinese medicinal
upper respiratory
radix
traditional chinese
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陈晓明
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BENGBU MINGRIXIN PHARMACEUTICAL Co Ltd
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BENGBU MINGRIXIN PHARMACEUTICAL Co Ltd
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Abstract

The invention provides a traditional Chinese medicinal prescription for treating upper respiratory infection. The prescription is prepared from the following traditional Chinese medicinal raw materials in parts by weight: 5-15 parts of radix scutellariae, 5-15 parts of pinellia ternata, 5-15 parts of immature bitter orange, 2-8 parts of raw ginger, 10-30 parts of malt, 5-15 parts of radix curcumae, 10-20 parts of radix bupleuri, 5-20 parts of bamboo shaving, 5-20 parts of poria, 5-15 parts of dried tangerine peel, 5-15 parts of folium eriobotryae, 2-8 parts of fructus amomi and 10-20 parts of rhizoma phragmitis. The traditional Chinese medicinal prescription is pharmacologically synergetic in traditional Chinese medicinal raw materials, has the effects of clearing heat and drying dampness, removing phlegm and resolving lumps, relieving exterior syndrome and dispelling cold, warming middle-jiao and preventing vomiting, strengthening spleen and appetizing, clearing heart and resolving depression, sterilizing and diminishing inflammation and the like, has the advantages of good treatment effect, high effective rate, no toxic or side effect to human bodies and the like when being used for treating upper respiratory infection, and is convenient to take.

Description

A kind of Chinese medicinal formulae for the treatment of upper respiratory tract infection
Technical field:
The present invention relates to Chinese medicine technical field, particularly a kind of Chinese medicinal formulae for the treatment of upper respiratory tract infection.
Background technology:
Upper respiratory tract infection is called for short upper sense, claims again common cold.It is the general name that comprises nasal cavity, pharynx or acute throat inflammation.The upper sense of broad sense is not a medical diagnosis on disease, but one group of disease comprises common cold, viral pharyngitis, laryngitis, herpangina, pharyngoconjunctival fever, bacterial pharyngotonsillitis.The upper sense of narrow sense claims again common cold, is modal acute infections of respiratory tract disease, be self limiting, but incidence rate is higher more.Adult is annual to be occurred 2~4 times, and child's incidence rate is higher, annual 6~8 times.All can fall ill the whole year, and winter-spring season is more.
Upper respiratory tract infection has 70%~80% to be caused by virus.Comprise rhinovirus, coronavirus, adenovirus, influenza and parainfluenza virus, respiratory syncytial virus, echovirus, Coxsackie virus etc.Separately there is 20%~30% upper sense to be caused by antibacterial.Antibacterial infect can direct infection or be secondary to viral infection after, with Hemolytic streptococcus, for the most common, next is hemophilus influenza, streptococcus pneumoniae, staphylococcus etc., is occasionally gram-negative bacteria.The various reasons that cause whole body or respiratory tract local defense function to reduce, as suffer from cold, drench with rain, abrupt change of climate, overtired etc. can making be formerly present in virus or antibacterial upper respiratory tract or that invade from the external world and bred rapidly, thereby brought out primary disease.A little less than old germling, immunologic hypofunction or suffer from patient's susceptible of chronic respiratory tract disease.
Doctor trained in Western medicine mainly adopts symptomatic treatment at present, there is no so far specific drug, and expensive, and curative effect can not be entirely satisfactory in addition.
Summary of the invention:
The present invention is exactly in order to make up the deficiency to upper respiratory tract infection in prior art, provides a kind for the treatment of for upper respiratory tract infection to have the Chinese medicinal formulae that therapeutic effect is good, effective percentage is high, human body is had no side effect.
The invention provides following technical scheme:
Treat a Chinese medicinal formulae for upper respiratory tract infection, it is characterized in that being made by the raw material of Chinese medicine of following parts by weight: Radix Scutellariae 5-15 part, Rhizoma Pinelliae 5-15 part, Fructus Aurantii Immaturus 5-15 part, Rhizoma Zingiberis Recens 2-8 part, Fructus Hordei Germinatus 10-30 part, Radix Curcumae 5-15 part, Radix Bupleuri 10-20 part, Caulis Bambusae In Taenia 5-20 part, Poria 5-20 part, Pericarpium Citri Reticulatae 5-15 part, Folium Eriobotryae 5-15 part, Fructus Amomi 2-8 part, Rhizoma Phragmitis 10-20 part.
Formula optimization is:
9 parts of Radix Scutellariae, 10 parts of Rhizoma Pinelliae, 7 parts of Fructus Aurantii Immaturuss, 5 parts, Rhizoma Zingiberis Recens, 20 parts, Fructus Hordei Germinatus, 10 parts of Radix Curcumaes, 12 parts of Radix Bupleuri, 12 parts of Caulis Bambusae In Taenia, 15 parts, Poria, 6 parts of Pericarpium Citri Reticulataes, 10 parts of Folium Eriobotryaes, 3 parts of Fructus Amomis, 15 parts of Rhizoma Phragmitiss.
Preparation method:
By the parts by weight in above-mentioned formula, the ethanol of first Fructus Aurantii Immaturus, Rhizoma Zingiberis Recens, Poria being put into 75% content soaked after 48 hours, collection ethanol extract is for subsequent use, extraction Pericarpium Citri Reticulatae volatile oil is for subsequent use, other raw material of Chinese medicine are decocted 3 times, add again extracting solution and volatile oil fully to stir after merging decoction liquor, be condensed into original volume 60% after, add Mel seasoning, every bottle of independent fill of every 50ml after sterilizing.
Form being described in detail as follows of each raw material of Chinese medicine of the present invention:
Radix Scutellariae: bitter in the mouth, cold in nature.Return lung, gallbladder, spleen, large intestine, small intestine meridian.There is heat clearing and damp drying, eliminating fire and detoxication, hemostasis, the effect such as antiabortive.Be usually used in hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood is told nosebleed, carbuncle sore tumefacting virus, the diseases such as frequent fetal movement.
Rhizoma Pinelliae: acrid in the mouth, warm in nature; Poisonous.Return spleen, stomach, lung meridian.There is drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the effects such as dissolving lump and resolving mass.Be usually used in abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm headache, vomiting regurgitation, breast gastral cavity painful abdominal mass is vexed, globus hystericus; Raw with external treatment carbuncle sucutaneous nodule.Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) is used for the diseases such as stopping nausea and vomiting by lowering the adverse flow of QI.The decoct of the Rhizoma Pinelliae, 0.6-1g/kgig or iv, have obvious antitussive effect to the cough due to cat iodine liquid injection thoracic cavity or electricity irritation superior laryngeal nerve, and can maintain the antitussive effect of more than 5 hours 0.6g/kg close to the effect of codeine lmg/kg.
Fructus Aurantii Immaturus: bitter in the mouth, pungent, sour, warm in nature.Return spleen, stomach warp.There is dispelling the stagnated QI removing food stagnancy, the effects such as loose painful abdominal mass of reducing phlegm.In being usually used in stagnating, stop, feeling of fullness distending pain, heavy after dysentery, constipation, the stagnant vapour lock thoracic obstruction of expectorant, blocked-up chest; Gastroptosis, proctoptosis, the diseases such as uterine prolapse.Experiment shows: the ethanol immersion of Fructus Aurantii Immaturus has inhibitory action to tubercule bacillus in vitro.
Rhizoma Zingiberis Recens: acrid in the mouth, slightly warm in nature.Return lung, spleen, stomach warp.There is the cold expelling of inducing sweat, warming middle-JIAO to arrest vomiting, the effects such as preventing phlegm from forming and stopping coughing.Be usually used in treating anemofrigid cold, gastrofrigid vomiting, the diseases such as cold-phlegm cough.Zoopery shows that alcoholic extract has excitation to anesthetized cat vasomotor center and respiratory center, also has direct excitation to heart.
Fructus Hordei Germinatus: sweet in the mouth, property is flat.Return spleen, stomach warp.Have promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite, moves back the diseases such as newborn relieving distension.Be usually used in food stagnation and do not disappear, abdominal distention, insufficiency of the spleen lack of appetite, milk smoulders, distending pain of the breast, women's disease such as wean.Zoopery shows: the similar ephedrine of its pharmacological action of hordenine that this product is contained.1.0mg/kg dosage can strengthen the nervous and motion in Cavia porcellus uterus, and increases with the increase of dosage.The cat bronchospasm that neostigmine is caused, can make it expansion, effective dose 0.5-1.0mg/kg, but very little to the effect of normal cats.Also have radioactive protective action.
Radix Curcumae: acrid in the mouth, hardship, cold in nature.Return liver, the heart, lung meridian.There is regulating qi to disperse stagnation, heart fire-clearing upset-relieving, the effects such as promoting the function of the gallbladder to alleviate jaundice.Be usually used in amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, calentura coma, the disease such as epilepsy is gone mad, jaundice dark coloured urine.Research shows: measure Rhizoma Curcumae Longae rhizome volatile oil antifungal activity by filter paper dick diffusion flat band method and show, volatile oil has larger inhibitory action to Penicllium chrysogenum.
Radix Bupleuri: bitter in the mouth, cold nature.Return liver, gallbladder meridian.There is reconciling superficies and interior, soothing the liver, the effects such as yang invigorating.Be usually used in treating cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, sub-official's prolapsus, the diseases such as proctoptosis.Research shows: this product has the effects such as convulsion, antipyretic, analgesia, calmness, antiinflammatory, enhancing blood capillary, antipathogen, enhancing cellular immunity.
Caulis Bambusae In Taenia: sweet in the mouth, cold nature.Attach to the lung and stomach meridians.Have removing heat-phlegm, the effect such as relieve restlessness and prevent vomiting.Be usually used in treating phlegm-heat cough, gallbladder fire is held expectorant under the arm, dysphoria with smothery sensation vomiting, and eye, middle wind-phlegm fan, aphasia with stiff tongue, gastropyretic vomiting, pregnancy reactions, the diseases such as frequent fetal movement are lost in palpitation with fear.This product also has increases urine chloride amount: have the effect that increases urine chloride amount; Increase blood glucose: in addition, increase in addition hyperglycemia.In addition, Caulis Bambusae In Taenia powder has stronger antibacterial action to Staphylococcus albus, bacillus subtilis, escherichia coli and typhoid fever bar castor etc. on plate.
Poria: sweet in the mouth, light, property is flat.GUIXIN, lung, spleen, kidney channel.There is promoting diuresis to eliminate damp pathogen, the effects such as spleen invigorating mind calming.Be usually used in treating edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia waits disease.Research shows: the ethanol extraction of this product is external can kill leptospira; This product has direct relexation to family's rabbits infestines, and the ulcer that rat pylorus ligation is formed has preventive effect, and can reduce gastric acid.In addition Poria can reduce blood glucose, and tincture, preserved material can suppress Bufo siccus isolated heart, and ether or ethanol extraction can make the heart shrink reinforcement.The Columba livia vomiting that Folium Digitalis Purpureae is caused is told effect without town.
Pericarpium Citri Reticulatae: bitter in the mouth, pungent, warm in nature.Return lung, spleen channel.There is regulating qi-flowing for strengthening spleen, the effects such as drying dampness to eliminate phlegm.Be usually used in fullness in the epigastrium and chest, lack of appetite and vomiting, the diseases such as cough with copious phlegm.Generation research thinks, the volatile oil of Pericarpium Citri tangerinae is irritant to eliminate the phlegm and the effect of expansion bronchus, and gastrointestinal smooth muscle is had to gentle stimulation, secretion that can facilitating digestion liquid and eliminate intestinal pneumatosis.
Folium Eriobotryae: bitter in the mouth, cold nature.Attach to the lung and stomach meridians.There is clearing away lung-heat to relieve cough, stopping nausea and vomiting by lowering the adverse flow of QI.For cough due to lung-heat, QI rising in reverse order dyspnea with rapid respiration, gastric heat vomiting, dysphoria with smothery sensation is thirsty.Research shows: in this product, contained Semen Armeniacae Amarum glycoside is decomposited Microamounts of Hydrogen cyanic acid at lower digestive tract by microbial enzyme, and the latter has sedation to respiratory center, therefore there is the antitussive effect of relievining asthma.
Fructus Amomi: acrid in the mouth, warm in nature.Return spleen, stomach, kidney channel.There is removing dampness appetizing, warming spleen and stopping diarrha, the effect such as regulate the flow of vital energy antiabortive.Be usually used in turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass is not hungry, Deficiency and coldness of spleen and stomach, and vomiting is had loose bowels, pregnancy reactions, the diseases such as frequent fetal movement.Research shows: this product is anticoagulant obviously; Can promote intestinal movement; Can make Cavia porcellus, rat small intestine intestinal tube shrink and strengthen, when escalated dose, intestinal tube be had to inhibitory action, performance tension force reduces, and amplitude reduces.
Rhizoma Phragmitis: sweet in the mouth, cold in nature.Attach to the lung and stomach meridians.There is clearing away heat and promoting production of body fluid, relieving restlessness, preventing or arresting vomiting, the effects such as diuresis.Be usually used in calentura excessive thirst, the gastric heat diseases such as the sound of vomiting, cough due to lung-heat, lung abscess vomiting pus, the puckery pain of pyretic stranguria of vomitting.
Each herbal pharmacology of the present invention is collaborative has heat clearing and damp drying, the loose painful abdominal mass of reducing phlegm, and cold expelling induces sweat, warming middle-JIAO to arrest vomiting, spleen benefiting and stimulating the appetite, heart fire-clearing upset-relieving, the effects such as anti-inflammation, have that therapeutic effect is good, effective percentage is high, human body are had no side effect for the treatment of upper respiratory tract infection, and the advantage such as convenient of taking medicine.
 
Detailed description of the invention:
Embodiment 1:
Treat a Chinese medicinal formulae for upper respiratory tract infection, it is characterized in that being made by the raw material of Chinese medicine of following parts by weight: 9 parts of Radix Scutellariae, 10 parts of Rhizoma Pinelliae, 7 parts of Fructus Aurantii Immaturuss, 5 parts, Rhizoma Zingiberis Recens, 20 parts, Fructus Hordei Germinatus, 10 parts of Radix Curcumaes, 12 parts of Radix Bupleuri, 12 parts of Caulis Bambusae In Taenia, 15 parts, Poria, 6 parts of Pericarpium Citri Reticulataes, 10 parts of Folium Eriobotryaes, 3 parts of Fructus Amomis, 15 parts of Rhizoma Phragmitiss.
Preparation method:
By the parts by weight in above-mentioned formula, the ethanol of first Fructus Aurantii Immaturus, Rhizoma Zingiberis Recens, Poria being put into 75% content soaked after 48 hours, collection ethanol extract is for subsequent use, extraction Pericarpium Citri Reticulatae volatile oil is for subsequent use, other raw material of Chinese medicine are decocted 3 times, add again extracting solution and volatile oil fully to stir after merging decoction liquor, be condensed into original volume 60% after, add Mel seasoning, every bottle of independent fill of every 50ml after sterilizing.
Embodiment 2:
Treat a Chinese medicinal formulae for upper respiratory tract infection, it is characterized in that being made by the raw material of Chinese medicine of following parts by weight: 8 parts of Radix Scutellariae, 8 parts of Rhizoma Pinelliae, 10 parts of Fructus Aurantii Immaturuss, 3 parts, Rhizoma Zingiberis Recens, 18 parts, Fructus Hordei Germinatus, 8 parts of Radix Curcumaes, 10 parts of Radix Bupleuri, 8 parts of Caulis Bambusae In Taenia, 13 parts, Poria, 10 parts of Pericarpium Citri Reticulataes, 10 parts of Folium Eriobotryaes, 4 parts of Fructus Amomis, 10 parts of Rhizoma Phragmitiss.
Preparation method:
By the parts by weight in above-mentioned formula, the ethanol of first Fructus Aurantii Immaturus, Rhizoma Zingiberis Recens, Poria being put into 75% content soaked after 48 hours, collection ethanol extract is for subsequent use, extraction Pericarpium Citri Reticulatae volatile oil is for subsequent use, other raw material of Chinese medicine are decocted 3 times, add again extracting solution and volatile oil fully to stir after merging decoction liquor, be condensed into original volume 60% after, add Mel seasoning, every bottle of independent fill of every 50ml after sterilizing.
Embodiment 3:
Treat a Chinese medicinal formulae for upper respiratory tract infection, it is characterized in that being made by the raw material of Chinese medicine of following parts by weight: 15 parts of Radix Scutellariae, 10 parts of Rhizoma Pinelliae, 10 parts of Fructus Aurantii Immaturuss, 8 parts, Rhizoma Zingiberis Recens, 30 parts, Fructus Hordei Germinatus, 15 parts of Radix Curcumaes, 20 parts of Radix Bupleuri, 15 parts of Caulis Bambusae In Taenia, 20 parts, Poria, 13 parts of Pericarpium Citri Reticulataes, 15 parts of Folium Eriobotryaes, 6 parts of Fructus Amomis, 20 parts of Rhizoma Phragmitiss.
Preparation method:
By the parts by weight in above-mentioned formula, the ethanol of first Fructus Aurantii Immaturus, Rhizoma Zingiberis Recens, Poria being put into 75% content soaked after 48 hours, collection ethanol extract is for subsequent use, extraction Pericarpium Citri Reticulatae volatile oil is for subsequent use, other raw material of Chinese medicine are decocted 3 times, add again extracting solution and volatile oil fully to stir after merging decoction liquor, be condensed into original volume 60% after, add Mel seasoning, every bottle of independent fill of every 50ml after sterilizing.
Use Chinese medicinal formulae of the present invention between 2007 to 2011,100 routine upper respiratory tract infection 100 examples to be treated, clinical report is as follows:
Physical data:
In 120 routine patients, women's 52 examples, male's 48 examples, at minimum 12 years old of age, maximum 65 years old, the course of disease was many at 1 day to 4 days, 30.6 years old mean age.
Diagnostic criteria:
Primary symptom: fever of the body, aversion to wind; Inferior disease: pharyngalgia, thirsty, cough, perspires, nasal obstruction watery nasal discharge.The micro-Huang of thin white fur of tongue or BOHUANG, floating and rapid pulse or sliding number.Possess 2 of primary symptoms and time disease more than 2 or 2, possess above-mentioned tongue pulse condition person simultaneously.
Therapeutic Method:
Oral 3 times of every day, each oral 50ml, 5 days was 1 course for the treatment of.
Criterion of therapeutical effect:
Cure: cardinal symptom, sign are alleviated completely or substantially, it is normal that objective indicator is recovered;
Effective: cardinal symptom, sign are obviously alleviated, objective indicator approaches normal;
Effective: cardinal symptom, sign take a turn for the better, and objective indicator makes moderate progress;
Invalid: cardinal symptom, sign are unchanged, objective indicator changes not obvious or increases the weight of.
Therapeutic outcome: in 120 routine patients, cure 82 examples and account for 68.4% of total number of persons, effective 22 examples account for 18.3% of total number of persons, and effective 13 examples account for 10.8% of total number of persons, and invalid 3 examples account for 2.5% of total number of persons, and total effective rate is 97.5%.
Model case:
1, Song, man, 26 years old, watery nasal discharge, low grade fever 2 days, acutely cough, tears accompany each other, and large dry stool is secret, yellowish or reddish urine.38.2 DEG C of temperature, pharyngeal cavity is slightly red and swollen, both sides antiadoncus, slightly congested, dry cough is frequent, and two pulmonary respiration sounds are clear, red tongue, yellow and thin fur, floating and rapid pulse is held concurrently sliding real.Taken the Chinese medicine composition that the present invention treats upper respiratory tract infection, 1 course for the treatment of, symptom is improved greatly, continue to take 1 course for the treatment of, and all diseases all disappear, and disease obtains recovery from illness.
2, Wang, female, 12 years old, heating, 39 DEG C of temperature, cough, abundant expectoration, color white matter is rare, gurgling with sputum, receive food still can, two just still adjust, uneasy sleeping at night, light red tongue, tongue is greasy in vain.Take the Chinese medicine composition that the present invention treats upper respiratory tract infection and treat, take after 1 day, temperature is normal, treats after 1 course for the treatment of, and all diseases all disappear, the peace of sleeping night and, diet two is just all normal, recovery from illness.
3, Lee, man, 12 years old.Suffer from more than pharyngitis two weeks, take during this time antibiotic medicine, do not heal always.Take after 1 course for the treatment of of Chinese medicine of the present invention, patient cures.

Claims (3)

1. treat a Chinese medicinal formulae for upper respiratory tract infection, it is characterized in that being made by the raw material of Chinese medicine of following parts by weight: Radix Scutellariae 5-15 part, Rhizoma Pinelliae 5-15 part, Fructus Aurantii Immaturus 5-15 part, Rhizoma Zingiberis Recens 2-8 part, Fructus Hordei Germinatus 10-30 part, Radix Curcumae 5-15 part, Radix Bupleuri 10-20 part, Caulis Bambusae In Taenia 5-20 part, Poria 5-20 part, Pericarpium Citri Reticulatae 5-15 part, Folium Eriobotryae 5-15 part, Fructus Amomi 2-8 part, Rhizoma Phragmitis 10-20 part.
2. according to a kind of Chinese medicinal formulae for the treatment of upper respiratory tract infection described in claim 1, it is characterized in that being made by the raw material of Chinese medicine of following parts by weight: 9 parts of Radix Scutellariae, 10 parts of Rhizoma Pinelliae, 7 parts of Fructus Aurantii Immaturuss, 5 parts, Rhizoma Zingiberis Recens, 20 parts, Fructus Hordei Germinatus, 10 parts of Radix Curcumaes, 12 parts of Radix Bupleuri, 12 parts of Caulis Bambusae In Taenia, 15 parts, Poria, 6 parts of Pericarpium Citri Reticulataes, 10 parts of Folium Eriobotryaes, 3 parts of Fructus Amomis, 15 parts of Rhizoma Phragmitiss.
3. treat the preparation method of the Chinese medicinal formulae of upper respiratory tract infection for one kind, it is characterized in that comprising the following steps: by the parts by weight in above-mentioned formula, the ethanol of first Fructus Aurantii Immaturus, Rhizoma Zingiberis Recens, Poria being put into 75% content soaked after 48 hours, collection ethanol extract is for subsequent use, extraction Pericarpium Citri Reticulatae volatile oil is for subsequent use, other raw material of Chinese medicine are decocted 3 times, after merging decoction liquor, add again extracting solution and volatile oil fully to stir, be condensed into original volume 60% after, add Mel seasoning, every bottle of independent fill of every 50ml after sterilizing.
CN201410233312.7A 2014-05-29 2014-05-29 Traditional Chinese medicinal prescription for treating upper respiratory infection Pending CN103990095A (en)

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Publication number Priority date Publication date Assignee Title
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Application publication date: 20140820