CN103977489A - Atomizer for pipeline - Google Patents

Atomizer for pipeline Download PDF

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Publication number
CN103977489A
CN103977489A CN201310699604.5A CN201310699604A CN103977489A CN 103977489 A CN103977489 A CN 103977489A CN 201310699604 A CN201310699604 A CN 201310699604A CN 103977489 A CN103977489 A CN 103977489A
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China
Prior art keywords
pipeline
chip
nebulizer
port
joint
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CN201310699604.5A
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CN103977489B (en
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陈永政
章波
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JIERUI ENTERPRISE (SHANGHAI) CO Ltd
Gentec Shanghai Corp
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JIERUI ENTERPRISE (SHANGHAI) CO Ltd
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Priority to CN201310699604.5A priority Critical patent/CN103977489B/en
Publication of CN103977489A publication Critical patent/CN103977489A/en
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Abstract

The invention discloses an atomizer for an integrated pipeline. The atomizer comprises a joint, a liquid medicine storage device and a miniature actuating chip, wherein the joint is of a three-way structure with hollow inside, a joint main body is provided with three end openings, the first end opening and the second end opening are standard connectors, the third end opening is a connecting end opening, the liquid medicine storage device is detachably connected with the third end opening of the joint in a sealed way, and the miniature actuating chip is arranged at a liquid medicine outlet part of the liquid medicine storage device and atomizes the liquid medicine entering the joint. The atomizer can effectively solve the problems of the existing atomization medicine supply device, can be used on a breathing pipeline or an anesthesia pipeline, and can also be used on ordinary medicine treatment.

Description

A kind of pipeline nebulizer
Technical field
The present invention relates to medical instruments field, be specifically related to special-purpose automatic ration microparticulate drugs drug delivery device.
Background technology
Spraying treatment is mainly used in the disease of respiratory tract such as imitating respiratory tract diseases such as breathing heavily COPD (block hard respiratory disorder and stop card), bronchitis.General treatment can be divided into two kinds a kind of for injection; Another kind of is the treatment of spray medicine.
The first injection system, it utilizes drug injection to be effective to blood vessel, but this mode can cause if medicine is along with blood is transmitted to whole body, and dose is unexpectedly controlled, cause the non-position of medicine that needs also to have medicine, there is side effect and need the upper relative spray pattern of position time of Drug therapy long; Moreover excessive use stylus printer enters, cause pain, child unexpectedly accepts, and for the sufferer of diabetes, its wound is not easy healing, is also not suitable for having an injection etc.
The second spray prescription formula, this mode mainly contains manual, pneumatic, ultrasonic three kinds, and the problem that these three kinds of modes can avoid injection to produce, can reduce dosage, and treatment speed is fast, greatly reduces treatment time.But this medicine applying device of three kinds has problem in actual use procedure:
Manual type, when spraying medicine by which, need to coordinate air-breathingly just can reach effectiveness, but child and old man be difficult for coordinating, the more important thing is that drug particles cannot reach best treatment granule 2-5um, the granule principle of this mode, at 5-10um, generally can only be done upper respiratory tract treatment.
Pneumatic mode, is smashed medicinal liquid by high pressure mode, and this mode is the most general current mode.But due to high pressure cause flow and pressure large, have and easily bring out effect and breathe heavily and wait side effect, in hospital's use procedure, may cause cross infection simultaneously, because need the gas of use compressor, the atmospheric gas of its use very likely carries other viruses, thereby greatly increases the chance of cross infection; In same which, drug particles cannot reach best treatment granule 2-5um, and the granule of this mode between 5-10um, can only be done upper respiratory tract treatment in principle
Ultrasonic power, which is mainly smashed medicinal liquid by higher-order of oscillation mode, and this mode can be destroyed the originality of medicine because producing heat and high frequency, so be not suitable for being used in conjunction with medicine, can only use at humidification.
Also have, the medicine applying device of above-mentioned three kinds of modes, due to its existing problem, cannot be used on breathing pipeline or anesthetic machine, and the scope of application is limited; Moreover, the medicine applying device of above-mentioned three kinds of modes in use by reason of heavy pressure and granule greatly cannot, thereby use on the child in 2-5 year.
Atomizing particle drift is uncontrollable owing to existing for the existing atomization medicine applying device of non-injection system described above, pressure is excessive may bring out the problems such as effect is breathed heavily, possibility cross infection, inconvenient operation, thereby has greatly limited its scope of application.
Summary of the invention
For the existing problem of medicine supply mode of above-mentioned non-injection, the object of the present invention is to provide a kind of integrated form pipeline nebulizer.This nebulizer can effectively solve the existing problem of existing atomization medicine applying device, can use at breathing pipeline or anaesthesia pipeline, also can use in general Drug therapy.
To achieve the above object, the present invention adopts following technical scheme:
A pipeline nebulizer, described nebulizer comprises:
Joint, the three-port structure that described joint is inner hollow, adapter body has three ports, and the first port and the second port are standard interface, and the 3rd port is as connectivity port;
Medicinal liquid storage device, described medicinal liquid storage device is dismountable to join with the 3rd port sealing joint, is provided with electric installation on it;
Miniature actuating chip, described miniature actuating chip is arranged at the medicine liquid outlet place of medicinal liquid storage device, and is electrically connected to the electric installation on medicinal liquid storage device, and atomization enters the medicinal liquid in joint by medicinal liquid storage device.
In preferred embodiment of the present invention, described medicinal liquid storage device is comprised of oblique medicine glass and upper cover, described oblique medicine glass comprises a cup and linkage section, described linkage section hollow, its one end is oblique to be arranged on the bottom of cup and to be communicated with it, the other end of linkage section joins as the outlet of oblique medicine glass and the 3rd port rotation of joint, and in this outlet, is provided with for settling the resettlement groove of miniature actuating chip; Described upper cover is equipped with the open top of oblique medicine glass cup; Described electric installation is arranged on the outside of linkage section and is electrically connected to the miniature actuating chip in resettlement groove.
Further, described electric installation comprises a conductive pole, two wire bonds on described conductive pole and miniature actuating chip, weld conductive pole and the liner assembling of miniature actuating chip, when mounted, first miniature actuating chip is arranged in the outlet of oblique medicine glass, installs liner and fix; Then pass through fixedly conductive pole of peace side shield, and conductive pole is exposed, to connect external power source, make miniature actuating chip energising work.
Further, cover on described and be provided with a dew terminal lug, reveal in terminal lug and be provided with silica gel plug.
Further, described miniature actuating chip comprises silica gel sheath, conducting strip, actuating chip, has circular atomization spray orifice on described actuating chip, activates chip and coordinates and join with conducting strip, and be placed in silica gel sheath.
Further, described actuating chip is that metal activates chip or plastics activate chip.
Further, the 3rd port of described joint becomes 75 ° of overturning angles with adapter body.
Further, described nebulizer also comprises integrated form driving host, and described integrated form driving host is electrically connected to electric installation.
Further, described integrated form driving host is directly to control integrated form driving host or timing controlled spraying integrated form driving host for spraying.
Further, described pipeline is connected to breathing circuit or breathing mask with nebulizer by pipe joint.
The integrated form pipeline obtaining according to such scheme has the following advantages when specifically using with nebulizer:
1. spraying granule concentrates on 2-5um (80%), can do upper respiratory tract, lower respiratory tract, bronchus and bronchioles treatment;
2. atomization rates can maintain 0.25-0.35/ml, can grasp accurately the amount of medication, helps doctor accurately judge the therapeutic effect reaching and reduce unwanted dose, can realize quantitative, regularly administration;
3. the pipe joint that the two ends of medicinal liquid storage device are standard can be connected on breathing pipeline or anaesthesia pipeline is used, and also can use in general Drug therapy.
Accompanying drawing explanation
Below in conjunction with the drawings and specific embodiments, further illustrate the present invention.
Fig. 1 is the assembling explosive view of nebulizer for integrated form pipeline;
Fig. 2 is the fit structure schematic diagram between cup and upper cover in nebulizer;
Fig. 3 is that integrated form pipeline connects and directly controls integrated form driving host schematic diagram for spraying with nebulizer;
Fig. 4 is that integrated form pipeline connects integrated form driving host schematic diagram for timing controlled spraying with nebulizer;
Fig. 5 is that integrated form pipeline is connected to adult or child's breathing circuit schematic diagram with nebulizer;
Fig. 6 is that integrated form pipeline is connected to infant breathes loop schematic diagram with nebulizer;
Fig. 7 is that integrated form pipeline coordinates breathing mask to use schematic diagram with nebulizer.
The specific embodiment
For technological means, creation characteristic that the present invention is realized, reach object and effect is easy to understand, below in conjunction with concrete diagram, further set forth the present invention.
Nebulizer provided by the invention is as a kind of automatic ration microparticulate drugs medicine applying device, and it can be applicable in various medical pipelines.This nebulizer is mainly comprised of pipe joint, medicinal liquid storage device and miniature actuating chip three parts.
Wherein pipe joint is for realizing being communicated with of nebulizer and various pipelines.The three-port structure that the main body of pipe joint is inner hollow for this reason, it has three ports, and the first port is ISO22OD standard interface, and the second port is 18ID/22ODD standard interface, and the 3rd port is as connectivity port, for being communicated with medicinal liquid storage device.
Medicinal liquid storage device, for storing medicine for treatment liquid, its Whole-dismountable joins with the 3rd port sealing joint, and the medicine liquid outlet of medicinal liquid storage device is towards the 3rd port of joint, and with its conducting.
Miniature actuating chip, it is arranged on the medicine liquid outlet place of medicinal liquid storage device, by producing vibration at high speed, will after the medical liquid atomizing in medicinal liquid storage device, be sprayed onto in pipe joint.
The nebulizer forming thus can effectively be controlled the granular size after atomization rates and medical liquid atomizing, thereby can be applicable to, in various medical pipelines, relevant respiratory tract disease be played to extraordinary therapeutic effect.
Referring to Fig. 1, it is depicted as the assembling explosive view that the integrated form pipeline forming based on such scheme is used nebulizer.
As seen from the figure, this integrated form pipeline is mainly comprised of silica gel plug 101, upper cover 102, sealing gasket 103, oblique medicine glass 104, side shield 105, miniature actuating chip 106, conductive pole 107, liner 108, sealing ring 109, pipe joint 110 with nebulizer 100.
The main body of pipe joint 110 is the T shape three-port structure that is the 75 ° of angles that tilt, and its one end is ISO22OD standard interface, and the other end relative with its level is 18ID/22ODD standard interface; The 3rd port one 10a is to tilt 75 ° of settings, and coordinates with oblique medicine glass 104 rotations.The 3rd port one 10a by these 75 ° of angles of inclination can reduce contacting of medicine and pipeline when spraying medicine, improves the ratio that dose is sprayed onto sufferer end.
Tiltedly medicine glass 104 and upper cover 102 coordinate the medicinal liquid storage device that forms nebulizer 100.Wherein oblique medicine glass 104 is for installing miniature actuating chip 106 and storing medicinal liquid.Tiltedly medicine glass 104 mainly comprises a cup 104a and a linkage section 104b, cup 104a integral body is that a cross section is the structure of U-shaped, linkage section 104b is hollow structure, its top arranges the bottom of cup 104b and is communicated with it, and the axis of the axis of cup 104b and linkage section 104b is at an angle, form thus oblique medicine glass 104; The bottom of linkage section 104b is as the outlet of oblique medicine glass, and the 3rd port one 10a rotation of itself and pipe joint 110 is joined, and is provided with for settling the resettlement groove of miniature actuating chip on the linkage section 104b bottom as tiltedly medicine glass outlet simultaneously.The oblique medicine glass 104 forming thus can be taken advantage of a situation to flow by angle and be avoided directly clashing into joint when spraying.
Upper cover 102 coordinates and joins with the opening of the cup 104a upper end of oblique medicine glass 104, and its profile is bamboo hat-shaped, for protecting the medicinal liquid of oblique medicine glass 104, when working, does not leak.In order to guarantee that the medicinal liquid in oblique medicine glass 104 does not leak, between upper cover 102 and cup 104a upper end open, be provided with sealing gasket 103, realize between upper cover 102 and cup 104a and seal and join.
Meanwhile, in the middle of the upper end of upper cover, be provided with one and reveal terminal lug 102a, can be used for drop and use, while not using drop, reveal terminal lug 102a and silica gel plug 101 and be used in conjunction with and prevent liquid leakage.
Referring to Fig. 2, in order to realize between upper cover and cup, to be connected fast and to separate, the present invention is provided with interior button 102b on upper cover 102, in the corresponding position of cup 104a upper end open, be provided with outer button 104b simultaneously, like this by by upper cover 102 toward lower cover on cup 104a, then rotating upper cover 102 makes in its upper cover button 102b and cup detain 104b outward to withhold, can realize fast connection; By reverse rotation, can realize fast separately.
Miniature actuating chip 106, as atomising device, is placed in the resettlement groove in oblique medicine glass 104 exits, forms corresponding spraying port, to flowed to the medicinal liquid of pipe joint 110 by oblique medicine glass 104, carries out atomization.
Due to the particularity of miniature actuating chip 106 work, it needs highly stable being fixed, and for this reason, between the 3rd port one 10a of miniature actuating chip 106 and pipe joint, liner 108 is set.The top of this liner 108 coordinates with miniature actuating chip 106, bottom is sealed and matched with the 3rd port one 10a of pipe joint by sealing ring 109, like this when oblique medicine glass 104 joins with the 3rd port one 10a rotation of pipe joint, tiltedly the resettlement groove on medicine glass 104 coordinates with the 3rd port one 10a of pipe joint the miniature actuating chip 106 compressing between the two, liner 108 and sealing ring 109, by thrust, miniature actuating chip 106 is stablized fixing, while liner 108 press seal circles 109, the 3rd port one 10a of realization and pipe joint is sealed and matched, effectively prevent that atomization gas from leaking.
The vibration that can produce high frequency in when work due to miniature actuating chip, in order to can be good at fixing braking chip, this liner 108 adopts the frustum cone structure of secondary, its large end and the tiltedly outlet of medicine glass 104, braking chip is fixed on to the outlet of oblique medicine glass 104, the 3rd port one 10a of the small end of liner 108 and pipe joint is sealed and matched; Its side is provided with for assembling the build-up member of conductive pole 107.
For miniature actuating chip 106, as figure shows, it mainly comprises actuating chip 106a, conducting strip 106b and silica gel sheath 106c, wherein, activating chip 106a is placed in conducting strip 106b, be electrically connected to it, and the conducting strip 106b integral body of installation actuating chip 106a is placed in silica gel sheath 106c.Activate on chip 106a and have circular atomization spray orifice, it can produce rise and fall in the situation that of energising, thereby the liquid of contact is produced to extruding, makes the atomization spray orifice of liquid on it discharge and forms fog.Conducting strip 106b powers to it from activating the surrounding of chip 106a, has both guaranteed to activate chip 106a and can obtain stable operating current, does not affect again the atomization action that activates chip 106a.Silica gel sheath 106c covers conducting strip 106b and conducting strip 106b and the cooperation place that is connected activating between chip 106a from surrounding sealing; to activating chip 106a and conducting strip 106b, form seal protection; avoid liquid to enter between the two; shift to conducting strip 106b to the stability that activates chip 106a power supply, thereby improve the stability of miniature actuating chip 106.
When concrete use, this actuating chip can adopt metal to activate chip or plastics activate chip.Wherein plastics activate chip and adopt macromolecular material support, and it can form different granular sizes according to the actual requirements, can do spraying treatment or have a plurality of patients to use simultaneously for different diseases and demand like this.
Due to miniature actuating chip 106 job demand electric energy, in order to obtain convenient from the external world, timely stable electric energy, this nebulizer is realized miniature actuating chip 106 by conductive pole 107 and is electrically connected to extraneous.As shown in the figure, conductive pole 107 is connected with the conducting strip on miniature actuating chip by wire.
In this programme, in order to can be good at conductive pole 107 being installed and being guaranteed the stability that conductive pole 107 matches with miniature actuating chip 106, this programme is formed for settling the connectivity port 104c of conductive pole 107 on oblique medicine glass.Thus when equipped miniature actuating chip 106, first, two wire bonds on miniature actuating chip 106, on conductive pole, then are assembled the conductive pole having welded and liner.
Then, miniature actuating chip is arranged in the outlet of oblique medicine glass, then installs liner and be fixed; Conductive pole 107 is installed in the connectivity port 104c on oblique medicine glass simultaneously.
Finally, the installation cooperation place installation side baffle plate 105 between conductive pole 107 and connectivity port 104c, prevents that by side shield 105 conductive pole 107 from up moving; Make conductive pole expose simultaneously, can connect external power source and make miniature actuating chip energising work.
The integrated form pipeline obtaining thus can access in different pipelines according to actual needs with nebulizer.By several examples, the service condition of nebulizer for pipeline of the present invention is once described below, but occupation mode of the present invention is not limited to this.
Referring to Fig. 3, it is depicted as integrated form pipeline and connects and directly control integrated form driving host 200 schematic diagrams for spraying with nebulizer 100.
During concrete connection, integrated form pipeline is connected use with the connectivity port on nebulizer 100 with 200 connecting pins 202 of integrated form driving host, and attaching plug 203 is connected with power supply; By control knob 201, realize driving host pipeline is controlled by the duty of nebulizer 100.
Referring to Fig. 4, it is depicted as integrated form pipeline and connects integrated form driving host 300 schematic diagrams for timing controlled spraying with nebulizer 100.
During concrete connection, integrated form pipeline is connected use with the connectivity port on nebulizer 100 with 300 connecting pins 305 of integrated form driving host, and attaching plug 306 is connected with power supply; By regulating time control knob 301/302 to carry out the adjustable spraying time, concrete realization can be shown by display screen 303.By control knob 304, realize driving host pipeline is controlled by the duty of nebulizer 100 again.
When concrete application, be connected with the nebulizer 100 for integrated form pipeline of driving host, it can be connected in adult or child's breathing circuit.Referring to Fig. 5, be connected with the nebulizer 100 for integrated form pipeline of driving host, pipe joint one end on it is connected to breathing circuit patient breeches joint end 400, and the other end and 18cm short tube 401 join, and realizes and uses nebulizer 100 for adult type or child's breathing circuit integrated form pipeline.
When concrete application, be connected with the nebulizer 100 for integrated form pipeline of driving host, it also can be connected in infant breathes loop.Referring to Fig. 6, be connected with the nebulizer 100 for integrated form pipeline of driving host, by the pipe joint on it, be connected to breathing circuit patient breeches joint end 500, can realize and use nebulizer 100 for adult type or child's breathing circuit integrated form pipeline.
Moreover this integrated form pipeline also can coordinate breathing mask to use with nebulizer 100, realizes hand-held nebulae inhalation.Specifically, referring to Fig. 7, will be connected with the nebulizer 100 for integrated form pipeline of driving host, by the pipe joint on it, be directly connected with breathing mask 600, can realize hand-held nebulae inhalation.
More than show and described ultimate principle of the present invention, principal character and advantage of the present invention.The technical staff of the industry should understand; the present invention is not restricted to the described embodiments; that in above-described embodiment and description, describes just illustrates principle of the present invention; without departing from the spirit and scope of the present invention; the present invention also has various changes and modifications, and these changes and improvements all fall in the claimed scope of the invention.The claimed scope of the present invention is defined by appending claims and equivalent thereof.

Claims (10)

1. a pipeline nebulizer, is characterized in that, described nebulizer comprises:
Pipe joint, the three-port structure that described pipe joint is inner hollow, pipe joint main body has three ports, and the first port and the second port are standard interface, and the 3rd port is as connectivity port;
Medicinal liquid storage device, described medicinal liquid storage device is dismountable to join with the 3rd port sealing joint, is provided with electric installation on it;
Miniature actuating chip, described miniature actuating chip is arranged at the medicine liquid outlet place of medicinal liquid storage device, and is electrically connected to the electric installation on medicinal liquid storage device, and atomization enters the medicinal liquid in joint by medicinal liquid storage device.
2. a kind of pipeline nebulizer according to claim 1, it is characterized in that, described medicinal liquid storage device is comprised of oblique medicine glass and upper cover, described oblique medicine glass comprises a cup and linkage section, described linkage section hollow, its one end is oblique to be arranged on the bottom of cup and to be communicated with it, and the other end of linkage section joins as the outlet of oblique medicine glass and the 3rd port rotation of joint, and in this outlet, is provided with for settling the resettlement groove of miniature actuating chip; Described upper cover is equipped with the open top of oblique medicine glass cup; Described electric installation is arranged on the outside of linkage section and is electrically connected to the miniature actuating chip in resettlement groove.
3. a kind of pipeline nebulizer according to claim 2, it is characterized in that, described electric installation comprises a conductive pole, two wire bonds on described conductive pole and miniature actuating chip, weld conductive pole and the liner assembling of miniature actuating chip, when mounted, first miniature actuating chip is arranged in the outlet of oblique medicine glass, installs liner and fix; Then pass through fixedly conductive pole of peace side shield, and conductive pole is exposed, to connect external power source, make miniature actuating chip energising work.
4. a kind of pipeline nebulizer according to claim 2, is characterized in that, covers on described and is provided with a dew terminal lug, reveals in terminal lug and is provided with silica gel plug.
5. a kind of pipeline nebulizer according to claim 1 and 2, it is characterized in that, described miniature actuating chip comprises silica gel sheath, conducting strip, actuating chip, has circular atomization spray orifice on described actuating chip, activate chip and coordinate and join with conducting strip, and be placed in silica gel sheath.
6. a kind of pipeline nebulizer according to claim 5, is characterized in that, described actuating chip is that metal activates chip or plastics activate chip.
7. a kind of pipeline nebulizer according to claim 1 and 2, is characterized in that, the 3rd port of described joint becomes 75 ° of overturning angles with adapter body.
8. a kind of pipeline nebulizer according to claim 1, is characterized in that, described nebulizer also comprises integrated form driving host, and described integrated form driving host is electrically connected to electric installation.
9. a kind of pipeline nebulizer according to claim 8, is characterized in that, described integrated form driving host is directly to control integrated form driving host or timing controlled spraying integrated form driving host for spraying.
10. according to a kind of pipeline nebulizer described in claim 1 or 8 or 9, it is characterized in that, described pipeline is connected to breathing circuit or breathing mask with nebulizer by pipe joint.
CN201310699604.5A 2013-12-18 2013-12-18 A kind of pipeline atomizer Active CN103977489B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019214281A1 (en) 2018-05-11 2019-11-14 泰安大陆医疗器械有限公司 Medical nebulizer
WO2021185055A1 (en) * 2020-03-20 2021-09-23 青岛未来移动医疗科技有限公司 Intelligent micro mesh nebulizer and nebulization system

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Publication number Priority date Publication date Assignee Title
CN1215346A (en) * 1996-02-13 1999-04-28 特鲁德尔医学有限公司 Nebulizer apparatus and method
CN1780655A (en) * 2003-03-04 2006-05-31 诺顿·希尔思凯尔有限公司 Medicament dispensing device with a display indicative of the state of an internal medicament reservoir.
CN101648041A (en) * 2009-09-02 2010-02-17 王成 Medical micropore atomization medicine absorber
WO2010045671A1 (en) * 2008-10-23 2010-04-29 Helmut Buchberger Inhaler
CN102711882A (en) * 2010-01-20 2012-10-03 皇家飞利浦电子股份有限公司 Method of using a temperature-based aerosol detector
CN202937920U (en) * 2012-10-31 2013-05-15 捷锐企业(上海)有限公司 Multifunctional T-shaped rotary joint mechanism

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1215346A (en) * 1996-02-13 1999-04-28 特鲁德尔医学有限公司 Nebulizer apparatus and method
CN1780655A (en) * 2003-03-04 2006-05-31 诺顿·希尔思凯尔有限公司 Medicament dispensing device with a display indicative of the state of an internal medicament reservoir.
WO2010045671A1 (en) * 2008-10-23 2010-04-29 Helmut Buchberger Inhaler
CN101648041A (en) * 2009-09-02 2010-02-17 王成 Medical micropore atomization medicine absorber
CN102711882A (en) * 2010-01-20 2012-10-03 皇家飞利浦电子股份有限公司 Method of using a temperature-based aerosol detector
CN202937920U (en) * 2012-10-31 2013-05-15 捷锐企业(上海)有限公司 Multifunctional T-shaped rotary joint mechanism

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019214281A1 (en) 2018-05-11 2019-11-14 泰安大陆医疗器械有限公司 Medical nebulizer
WO2021185055A1 (en) * 2020-03-20 2021-09-23 青岛未来移动医疗科技有限公司 Intelligent micro mesh nebulizer and nebulization system

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