CN103977282A - Cordyceps sinensis traditional Chinese medicine preparation for promoting fracture healing - Google Patents
Cordyceps sinensis traditional Chinese medicine preparation for promoting fracture healing Download PDFInfo
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- CN103977282A CN103977282A CN201410218838.8A CN201410218838A CN103977282A CN 103977282 A CN103977282 A CN 103977282A CN 201410218838 A CN201410218838 A CN 201410218838A CN 103977282 A CN103977282 A CN 103977282A
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Abstract
The invention discloses a cordyceps sinensis traditional Chinese medicine preparation for promoting fracture healing. The cordyceps sinensis traditional Chinese medicine preparation is obtained as follows: mixing and crushing cordyceps sinensis, potentilla chinensis, abelmoschus manilhot, pterospermum heterophyllum, desmodium multiflorum root, coriander seed, moleplant seed, corn stigma, radix bupleuri, saffron crocus, bark of ash, mallotus root, jasmine root, sweetscented oleander leaf, locust tree root, farfugium japonicum, semen cassia, flos farfarae, honeysuckle, fructus forsythia, isatis root, platycodon grandiflorum, liquidambar formosana hance and seed of cowherb into fine powder; placing in a medicine-boiling appliance; adding pure water and soaking for 1 hour; boiling for 20 minutes with slow fire after boiling with strong fire, cooling, filtering to remove dregs of a decoction, adding epomediol acetic acid and acetic acid into medicine liquor, and uniformly mixing to obtain the cordyceps sinensis traditional Chinese medicine preparation. While being used for treating fracture, the externally-used traditional Chinese medicine preparation disclosed by the invention can be used for relieving swelling and pains of a fracture part, and shortening the fracture clinical healing time, and is a more ideal medicine for treating the fracture. Compared with the prior art, the cordyceps sinensis traditional Chinese medicine preparation disclosed by the invention has the beneficial effects of being convenient to use, quick in fracture healing, short in treatment period and free of side effect.
Description
Technical field
The present invention relates to technical field of Chinese medicines, specifically refer to a kind of Cordyceps Chinese medicine preparation that promotes union of fracture.
Background technology
Fracture means a kind of disease that causes sclerotin partially or even wholly to rupture due to the reason such as wound or pathology.Its main clinical manifestation is: fracture site has limitation pain pain and tenderness, local swelling and occur ecchymosis, and limb function position or completely lose, still can there is cacomelia and abnormal movement in complete fracture.
Union of fracture is one and complicated osteanagenesis repair process, be subject to whole body and local permitted multifactorial impact and adjusting, approximately 5%～10% fracture is due to a variety of causes generation delayed union or disunion, have a strong impact on people's life quality, how accelerating union of bone fracture, improve healing quality is the common problem of paying close attention to of medical circle always.
The types of drugs of at present treatment fracture is a lot, but because effect is not fairly obvious, treatment cycle is long, easily intersects repeated infection, uses inconvenience, and untoward reaction is many; If there is no timely and effective processing, meeting delay treatment, easily causes sequela, and conventional treatment is cleaned again, causes patient painful again.
Cordyceps is China's tradition rare Chinese medicine, has cough-relieving, reduces phlegm, reduces the multiple pharmacological effect such as serum cholesterol, adjusting and enhancing immunity, antitumor.Cordyceps is the larva cadaveric complex of Stroma and host's Hepialidae insecticide Hepialus etc. thereof of Clavicipitaceae plant Cordyceps fungus.Mainly be distributed in alpine scrub and the mesophorbium, coryphile of the ground height above sea level 3500 ~ 5000m such as Qinghai, Tibet, Sichuan, Yunnan.Because Cordyceps has its strict parasitics and special growth geographical environment, output is quite limited, and resource is more in short supply.
The present invention adopts Cordyceps and other multiple Chinese herbal medicine compatibilities, the medicine for external use of the promotion union of fracture that process is processed into.It has feature easy to use, that union of fracture is fast, treatment cycle is short.
Summary of the invention
Technical problem to be solved by this invention is, provides a kind of for promoting the Chinese medicine preparation of fracture surgery healing, adopts this Chinese medicine preparation can promote blood circulation promoting and blood stasis dispelling, make QI and blood unobstructed, the stagnant dissipation of the stasis of blood, new bone proliferation, accelerate the healing of fracture, overcome the various defects that prior art exists.The present invention adopts following technical scheme to achieve these goals:
The present invention is achieved by the following technical solutions:
A kind of Cordyceps Chinese medicine preparation that promotes union of fracture, its preparation method is: first take Cordyceps 2 weight portions, Herba Potentillae Chinensis 5 weight portions, Abelmoschus manihot （L.） Medic 3 weight portions, Pterospermi Heterophylli 3 weight portions, Herba desmodii multifloi root 5 weight portions, ceriander seed 5 weight portions, Semen Euphorbiae 2 weight portions, Stigma Maydis 3 weight portions, Radix Bupleuri 8 weight portions, Stigma Croci 5 weight portions, Cortex Fraxini 5 weight portions, Radix Malloti Apelitae 3 weight portions, Radix Fructus Gardeniae 5 weight portions, sweetscented oleander leaf 3 weight portions, pagoda tree root 8 weight portions, Farfugium japonicum 3 weight portions, Semen Cassiae 1 weight portion, Flos Farfarae 5 weight portions, Flos Lonicerae 3 weight portions, Fructus Forsythiae 3 weight portions, Radix Isatidis 3 weight portions, Radix Platycodonis 5 weight portions, Fructus Liquidambaris 2 weight portions, Semen Vaccariae 2 weight portions, after mixing, be ground into smalls, put into drug-decocting appliance, add 1000 weight portion pure water to soak 1 hour, after boiling with high heat, use slow fire boiling 20min instead, cooling, remove by filter medicinal residues, in medicinal liquid, add epomediol 2 weight portions, acetic acid 5 weight portions, mix homogeneously and get final product.
The using method of the Chinese medicine preparation of above-mentioned promotion union of fracture: external application fracture affected part.Within 3rd, change dressings 1 time.
Chinese medicine preparation of the present invention promotes the medicine principle of union of fracture: fracture is after early treatment, eliminate gradually with stagnation of QI and blood, but congestive edema not yet disappears to the greatest extent, knochenbruch not yet connects, though or tentatively connect and not yet solid, controlling should promoting regeneration of tissue by regulating nutrient QI, nourishing the liver and kidney, strong muscles and bones is main, and assistant is with blood circulation promoting and blood stasis dispelling, and relaxing muscles and tendons and activating QI and blood in the collateral is in order to joint.Chinese medicine preparation of the present invention have invigorate blood circulation, blood stasis dispelling, circulation of qi promoting, dispel the wind, effect of detumescence, pain relieving, heat clearing away, removing toxic substances, granulation promoting, dredging collateral, synthetism; Reducing swelling and alleviating pain fast, promoting blood circulation by removing blood stasis, improves blood circulation, removes slough; Promote growth hormone secretion, reunion of bone, improve osteoblast activity and index, increase osteoblast and amount of osteoclast, accelerate fracture healing as early as possible.
Epomediol for the auxiliary treatment of acute and chronic hepatopathy, recovers hepatocyte function by film ATP enzyme and the effect of gland cyclase of acid in the prior art, and the Golgi body while making alcoholism recovers normal function.In clinical practice of the present invention, inventor is surprised to find that epomediol (molecular formula: C10H18O3) and acetic acid add in the herb liquid in the technical program simultaneously, can effectively accelerate the absorption of active ingredient of Chinese herbs, improves the speed of union of fracture, determined curative effect, without other side effect.
When Chinese medicine for outer use treatment fracture of the present invention, can alleviate fracture site swelling, pain, shorten the clinical union of bone time, be the comparatively ideal medicine for the treatment of fracture.The present invention with respect to the beneficial effect of prior art is: easy to use, union of fracture is fast, treatment cycle is short, have no side effect.
detailed description of the invention:
Below in conjunction with embodiment, the present invention is further illustrated.
Embodiment 1
First take Cordyceps 2g, Herba Potentillae Chinensis 5g, Abelmoschus manihot （L.） Medic 3g, Pterospermi Heterophylli 3g, Herba desmodii multifloi root 5g, ceriander seed 5g, Semen Euphorbiae 2g, Stigma Maydis 3g, Radix Bupleuri 8g, Stigma Croci 5g, Cortex Fraxini 5g, Radix Malloti Apelitae 3g, Radix Fructus Gardeniae 5g, sweetscented oleander leaf 3g, pagoda tree root 8g, Farfugium japonicum 3g, Semen Cassiae 1g, Flos Farfarae 5g, Flos Lonicerae 3g, Fructus Forsythiae 3g, Radix Isatidis 3g, Radix Platycodonis 5g, Fructus Liquidambaris 2g, Semen Vaccariae 2g, after mixing, be ground into smalls, put into drug-decocting appliance, add 1000g pure water to soak 1 hour, after boiling with high heat, use slow fire boiling 20min instead, cooling, remove by filter medicinal residues, in medicinal liquid, add epomediol 2g, acetic acid 5g, mix homogeneously obtains the Cordyceps Chinese medicine preparation that promotes union of fracture.
Clinical trial: choose the routine fracture patient in Hefei City, Anhui Province 100 (wherein: male 51 people, women 49 people; The range of age is 16 ~ 67 years old, 44 years old mean age), be equally divided at random two treatment groups, every group of 50 routine patients.Wherein, after treatment group 1 adopts and resets, plintlet fixedly adds " a kind of Cordyceps Chinese medicine preparation that promotes union of fracture " that apply the embodiment of the present invention 1, within 3rd, changes dressings once; After treatment group 2 adopts and resets, plintlet fixedly adds conventional therapy, and the fracture patient X sheet situation to treatment group 1 and treatment group 2 in therapeutic process is added up.
The fractures result for the treatment of group 1 shows: it is 10 days that primary callus generates the shortest time, and maximum duration is 21 days, and it is 33 days that callus is transformed moulding shortest time phase, and maximum duration is 51 days.
The fractures result for the treatment of group 2 shows: it is 16 days that primary callus generates the shortest time, and maximum duration is 45 days, and it is 62 days that callus is transformed moulding shortest time phase, and maximum duration is 98 days.
Below by concrete case, the curative effect of " promoting the Cordyceps Chinese medicine preparation of union of fracture " provided by the invention is done to further checking.
Case 1: Liao, man, 25 years old, in vehicle accident in August, 2013, is two Fracture of femur through hospital diagnosis.The in the situation that of anesthesia, carry out gravity traction reset; The in the situation that of traction, the Chinese medicine preparation of the external application embodiment of the present invention 13 days, makes to eliminate and swells and ache, determine in the situation of correct position with x-ray again, use plintlet to fix, continue this Chinese medicine preparation of external application after one month, can lean on below and turn walking, after March, fracture line disappears, functional rehabilitation.
Case 2: Peng, female, 32 years old, accidentally fall down by bike and cause left chi, scratch bone closed fracture in April, 2013, carry out manual reduction, plintlet is fixed, the Chinese medicine preparation of the external application embodiment of the present invention 1.The medication elimination of swelling and ache in the 3rd day, within the 16th day, the visible primary callus of x-ray generates, and within 34 days, visible bone trabecula passes through fracture line.
Case 3: money, man, 39 years old, injured by a crashing object by stone in June, 2013, cause right lower limb Tibia-fibula fracture, after hospital resets, adopt Gypsum Fibrosum to fix and conventional therapy, treat swelling after 3 months and disappear, but X sheet shows that having no callus generates.Rear employing plintlet is fixed, the Chinese medicine preparation of the external application embodiment of the present invention 1, and medication 15 days, the visible primary callus of X sheet generates substantially, continues the 41st day bone trabecula of medication and passes through fracture line.
Case 4: Wang, man, 43 years old, in careless traumatic injury of in April, 2011, be right hand upper end breaking property fracture through hospital diagnosis, at local hospital treatment one to no effect monthly, after being introduced, use the Chinese medicine preparation of the embodiment of the present invention 1 after 5 days, pain obviously alleviates, and continues to be used in conjunction 30 days and all cures.
Case 5: hear certain, man, 58 years old, traumatic injury accidentally in about in May, 2013, patient feels that bipod aches, waist also has slight pain, is that lumbar vertebra is slightly fractured through hospital diagnosis, and the Chinese medicine preparation of the rear use embodiment of the present invention 1 is after 45 days, all cure, disappearance that bipod is ached and waist is slightly keenly felt, through hospital's check, without abnormal.
Claims (1)
1. promote a Cordyceps Chinese medicine preparation for union of fracture, it is characterized in that preparation method is: first take Cordyceps 2 weight portions, Herba Potentillae Chinensis 5 weight portions, Abelmoschus manihot （L.） Medic 3 weight portions, Pterospermi Heterophylli 3 weight portions, Herba desmodii multifloi root 5 weight portions, ceriander seed 5 weight portions, Semen Euphorbiae 2 weight portions, Stigma Maydis 3 weight portions, Radix Bupleuri 8 weight portions, Stigma Croci 5 weight portions, Cortex Fraxini 5 weight portions, Radix Malloti Apelitae 3 weight portions, Radix Fructus Gardeniae 5 weight portions, sweetscented oleander leaf 3 weight portions, pagoda tree root 8 weight portions, Farfugium japonicum 3 weight portions, Semen Cassiae 1 weight portion, Flos Farfarae 5 weight portions, Flos Lonicerae 3 weight portions, Fructus Forsythiae 3 weight portions, Radix Isatidis 3 weight portions, Radix Platycodonis 5 weight portions, Fructus Liquidambaris 2 weight portions, Semen Vaccariae 2 weight portions, are ground into smalls after mixing, put into drug-decocting appliance, add 1000 weight portion pure water to soak 1 hour, after boiling with high heat, use slow fire boiling 20min instead, cooling, remove by filter medicinal residues, add epomediol 2 weight portions in medicinal liquid, acetic acid 5 weight portions, mix homogeneously obtains the Cordyceps Chinese medicine preparation of described promotion union of fracture.
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| CN201410218838.8A CN103977282A (en) | 2014-05-23 | 2014-05-23 | Cordyceps sinensis traditional Chinese medicine preparation for promoting fracture healing |
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| CN201410218838.8A CN103977282A (en) | 2014-05-23 | 2014-05-23 | Cordyceps sinensis traditional Chinese medicine preparation for promoting fracture healing |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20180327272A1 (en) * | 2015-11-10 | 2018-11-15 | Japan Science And Technology Agency | Supported metal material, supported metal catalyst, and ammonia synthesis method using the same |
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2014
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20180327272A1 (en) * | 2015-11-10 | 2018-11-15 | Japan Science And Technology Agency | Supported metal material, supported metal catalyst, and ammonia synthesis method using the same |
| US10759668B2 (en) * | 2015-11-10 | 2020-09-01 | Japan Science And Technology Agency | Supported metal material, supported metal catalyst, and ammonia synthesis method using the same |
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Application publication date: 20140813 |
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