CN103931984A - Effervescent tablet used for in-time physical power replenishment in exercise, and applications thereof - Google Patents

Effervescent tablet used for in-time physical power replenishment in exercise, and applications thereof Download PDF

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Publication number
CN103931984A
CN103931984A CN201410027136.1A CN201410027136A CN103931984A CN 103931984 A CN103931984 A CN 103931984A CN 201410027136 A CN201410027136 A CN 201410027136A CN 103931984 A CN103931984 A CN 103931984A
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effervescent tablet
vitamin
acid
parts
physical efficiency
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邹丹
刘鹏
陈卡
张婷
张乾勇
朱俊东
糜漫天
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Third Military Medical University TMMU
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Third Military Medical University TMMU
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/385—Concentrates of non-alcoholic beverages
    • A23L2/39—Dry compositions
    • A23L2/395—Dry compositions in a particular shape or form
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/40—Effervescence-generating compositions
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
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    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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Abstract

The invention discloses an effervescent tablet used for in-time physical power replenishment in exercise, and applications thereof. The effervescent tablet comprises following raw materials, by weight, maltooligosaccharide, citric acid, sodium chloride, magnesium carbonate, potassium citrate, calcium lactate, vitamin B1, vitamin B2, ascorbic acid, tartaric acid, sodium bicarbonate, L-Arginine, taurine, caffeine, and green tea extract. The effervescent tablet is used for preparation of medicines, food, and health products which are used for rapid body micronutrient replenishment; is capable of replenishing vitamins and mineral matters which are consumed greatly because of active body metabolism caused by exercise, maintaining body acid-base equilibrium, delaying body sport fatigue, increasing body tolerance, and improving body states quickly; is suitable for rapid supplement of electrolyte and other nutrients of army officers and soldiers, rescue personnel, sports enthusiasts, wilderness explorers, or tourists; and is beneficial for rapid improvement of body exercise and reaction capacity.

Description

For effervescent tablet and the application thereof of supply physical efficiency in time of moving
Technical field
The present invention relates to a kind of effervescent tablet, particularly a kind of for effervescent tablet and the application thereof of supply physical efficiency in time of moving.
Background technology
During motion, metabolism is vigorous, be unable to do without the supply of energy, and the energy source of motion is nutrient, and the recovery of various nutrients and motion physical efficiency has close relationship.Therefore,, during training, except the great energy reserve of needs, also need micronutrient (being vitamin and mineral matter) to help metabolism.
Vitamin is in motion exercise process, and the supplementary of vitamin is the problem of significant, and in competitive sport training, some vitamin can directly have influence on athletic locomitivity, therefore finds that motion may cause the consumption of some vitamin.The famous flavones of looking of vitamin A, its main Physiological Function is the raw material that forms visual purple in retina, maintains suitable vision and epithelial tissue, also participates in maintaining of skeleton development and immunologic function.For being engaged in the motor activity that vision requirement is high, as motions such as shooting, table tennis, shuttlecock, vollyball, boxings, vitamin A consumption may be larger, so will give prominence to the supplementary importance of vitamin A.The prerequisite material of vitamin A is beta carotene.Vitamin A is liposoluble vitamin, and long-term too much supplementing can cause intoxicating phenomenon, supplements too much beta carotene and can not cause intoxicating phenomenon.Vitamin E is liposoluble vitamin, and it is a kind of polyphenoils, is the antioxidant of polybasic unsaturated fatty acid on cell and Subcellular membrane, and it can be used as the infringement that Green Tea Extract substance protection cell membrane is avoided lipid peroxidation.The people of the balanced diet E that is generally seldom deficient in vitamin, therefore does not need specially to supplement.The major function of vitamin B1 is to using the form of diphosphothiamine as the coenzyme of pyruvate dehydrogenase system in glycometabolism, and relevant with the composition and decomposition of neurotransmitter acetylcholine.During Vitamin B1 deficiency, there will be more pyruvic acid accumulation and generate lactic acid, thereby accelerate tired generation, reduce aerobic capacity.The absorption of vitamin B1 and energy are taken in height correlation, and the requirement of vitamin B1 depends on whole energy consumption, especially relevant with the consumption of glucide.When glucide is taken in when more, the intake of vitamin B1 also should corresponding increase.Vitamin B2 (riboflavin) is the coenzyme composition of flavo-enzyme in the interior mitochondrial respiratory chain of constituting body, in mitochondria electronics transmission system, plays an important role, and therefore exercise tolerance is had to obvious impact.During Vitamin B2 deficiency, can make people's muscle weak, locomitivity significantly declines, and easily tired.Vitamin is the composition of several respiratory chains, thereby its intake also should be relevant with energetic supersession.Vitamin C is the biosynthesis that participates in collagen, catecholamine and carnitine, and it is effective antioxidant, has reversible redox, and it also contributes to absorption, transhipment and the storage of nonheme iron.In motion exercise, replenishing vitamins C can improve body immunity, reduces fatigue and DOMS, and Cell protection is avoided the damage of free radical.Vitamin C is one of nutrient using the widest, most study.
Mineral matter is the adjusting nutrient that body weight for humans is wanted, and every kind of mineral matter has important function, has plenty of the important component that forms some tissue of body, and what have is the important Auto-regulator that maintains isohydria, by participate in forming of body endoenzyme and hormone.The reserves of mineral matter generally can meet body requirement in human body, are difficult for causing shortage, but (as large amount of exercise motion, meals imbalance or Special Geographic living environment) also there will be the shortage of some mineral matter under special circumstances.In motion, can cause consumption or the loss of mineral matter, lose is mainly to perspire to lose, the main component of sweat is sodium ion, potassium ion, calcium ion etc., these loss can cause body skeletal muscle, cardiac muscle and nerve impulse not to carry out, can not execution, also easily cause injured (please supplement) therefore, motion exercise also will be considered supplementing of mineral matter.
Summary of the invention
In view of this, the object of the present invention is to provide a kind of effervescent tablet and application thereof for the timely supply physical efficiency of moving, can improve the blood-sugar content of the rear body of motion; The blood-sugar content of body while maintaining persistent movement; Delay the generation of body movement fatigue; Reduce the Serum lactic acid content of the rear body of motion; Improve the ability of body endurance exercise, can quickly supplement energy, promote rapidly fuselage state, be applicable to the officers and men of army, various rescue personnel, like the needs of the rapid makeup energy of players, field exploration or travel staff, electrolyte and other nutrient, contribute to improve rapidly body movement and respond.
Of the present invention a kind of for the effervescent tablet of supply physical efficiency in time that moves, effervescent tablet raw material comprises following component by weight: oligomeric maltose 50-90 part, citric acid 1-30 part, sodium chloride 0.1-5 part, magnesium carbonate 0.1-5 part, potassium citrate 0.1-5 part, calcium lactate 0.5-5 part, 0.01-1 part vitamin B1,0.01-1 part vitamin B2, ascorbic acid 0.5-5 part, tartaric acid 0.1-5 part, sodium acid carbonate 0.1-5 part, L-arginine 0.1-5 part, taurine 1-20 part, caffeine 0.01-1 part, green-tea extract 1-20 part;
Further, effervescent tablet raw material comprises following component by weight: oligomeric maltose 55-85 part, citric acid 5-25 part, sodium chloride 0.5-4 part, magnesium carbonate 0.5-4 part, potassium citrate 0.5-4 part, calcium lactate 0.5-5 part, 0.01-1 part vitamin B1,0.01-1 part vitamin B2, ascorbic acid 0.5-4 part, tartaric acid 0.5-5 part, sodium acid carbonate 0.5-5 part, L-arginine 0.5-5 part, taurine 1-15 part, caffeine 0.01-1 part, green-tea extract 1-18 part;
Further, effervescent tablet raw material comprises following component by weight: oligomeric maltose 60-80 part, citric acid 5-20 part, sodium chloride 0.5-2 part, magnesium carbonate 0.5-2 part, potassium citrate 0.5-2 part, calcium lactate 0.5-3 part, 0.01-1 part vitamin B1,0.01-1 part vitamin B2, ascorbic acid 0.5-3 part, tartaric acid 0.5-3 part, sodium acid carbonate 0.5-3 part, L-arginine 0.5-3 part, taurine 1-10 part, caffeine 0.01-1 part, green-tea extract 1-15 part;
Further, effervescent tablet raw material comprises following component by weight: 70 parts of oligomeric maltoses, 10 parts of citric acids, 1 part, sodium chloride, 1 part, magnesium carbonate, 1 part of potassium citrate, 1.5 parts, 0.1 part vitamin B1 of calcium lactate, 0.1 part of vitamin B2,1.5 parts, ascorbic acid, 1 part, tartaric acid, 1 part of sodium acid carbonate, 1 part of L-arginine, 5 parts of taurines, 0.5 part of caffeine, 5 parts of green-tea extracts;
Further, should can add the carrier that can accept in medical science or bromatology or health care conduct and learning to make preparation for the effervescent tablet of supply physical efficiency in time that moves;
The present invention also disclose a kind of effervescent tablet for the timely supply physical efficiency of moving the medicine for the preparation of to body makeup energy, for to body makeup energy health products, for the application of the food to body makeup energy.
Beneficial effect of the present invention:
Of the present invention can be the supplementary enough required nutriments of body such as electrolyte, sodium chloride and vitamin of body for the effervescent tablet of supply physical efficiency in time that moves, can help energetic supersession, maintain the acid-base balance of human body, the reparation can be used as after the supplementary and training before training is used.
Oligomeric maltose, have easy to digest, low sugariness, hyposmosis characteristic, can extend the energy supply time, strengthen human body endurance, the functions such as antifatigue, human body is through overweight (or large) physical demands and after strenuous exercise, be prone to dehydration for a long time, energy reserves, consumption blood sugar reduces, fever, muscle nerve conduction is influenced, a series of physiological change such as functional disorders of brain and symptom, and after edible oligomeric maltose, can not only keep blood sugar level, reduce the generation of blood lactic acid, and insulin secretion balance, human trial proves, after use compound sugar, endurance and function power can increase more than 30%, effect is very obvious.Oligoisomaltose can also keep moisture to be difficult for evaporation, and crystallization effective to maintaining of the moistening and quality of varieties of food items and that can suppress sucrose and glucose forms, and can prevent age of starch, and extend the holding time to slightly depositing the food of i.e. sclerosis.
Tartaric acid is used as acidulant, flavouring, complexing agent, antioxidant synergist and effervescent agent in medicament.Tartaric acidity is strong compared with citric acid, soluble in water, is a kind of good effervescence acid agent.Take tartaric acid as effervescence acid agent, effervesce great efforts, hygroscopicity is less, is convenient to production operation.
Citric acid is main in medicament is current most widely used effervescent agent acid source as flavouring, buffer, antioxidant synergist, acid effervescent agent, is suitable for various effervescent tablets.Citric acid is soluble in water, mouthfeel good, but there is very strong hygroscopicity, under 65%～75% relative humidity, can absorb large quantity of moisture, in production and storage, often cause sticking, particle difficultly to dry, the problems such as sheet easily rise, therefore, by the tartaric acid as acid source, citric acid and as playing synergy by effective proportioning collaborative other components between the sodium acid carbonate of alkali source, and as gas-producing disintegrant, not only can improve the problem of moisture absorption, sticking and acid-base reaction that mouthfeel can also solve citric acid.
The metabolism of vitamin B1, vitamin B2 and sugar, protein, fat is closely related, be critical material in glycometabolism process, the metabolism in wide participation body, promotes albumen synthetic, accelerate fat oxidation energy supply, contributes to delayed motion fatigue to occur and promotes fatigue recovery.
Ascorbic acid can be protected other antioxidant, as VitAVitE, unrighted acid, prevents the injury of radical pair human body, and improves the emergency capability of body.Be applicable to people because being engaged in strenuous exercise and highly intensive labour to supplement because of the too much vitamin Cs of a large amount of losses of sweating.
L-arginine, claims again L-arginine, is the important source material of synthetic protein and creatine, plays the endurance, explosive force and the quick-reaction capability that improve sportsman, trainer in effervescent tablet of the present invention.
Green-tea extract is to adopt excellent green tea tealeaves after suitable technique is extracted, and spraying is dry to be formed.Its main composition is Tea Polyphenols and caffeine.Tea Polyphenols is the general name of multiple aldehydes matter in tealeaves, also be the main component of health care in tealeaves, its effect of removing free radical is obviously better than vitamin C and E, and has synergy with vitamin C, E, contributes to remove the free radical producing in intensity movements process; And the excited cerebral cortex of caffeine energy has quick stimulating effect.
Taurine is the end-product of Metabolism of Sulfur-Containing Amino Acids, is a kind of conditionally essential amino acid.It can accelerate glucose and enter cell, promotes glycometabolism; Can increase the activity of various lipase, accelerate fat splitting.Research shows, in body, taurine is essential to maintaining locomitivity, and the external world gives supplementation of taurine can increase locomitivity; In addition, give motion rat supplementation of taurine, can obviously improve branched-amino acid concentration in blood plasma, and aromatic amino acid concentration is without significant change, thereby keep the excitatory state of maincenter, the appearance of lag motion fatigue and alleviate the degree of exercise induced fatigue.And taurine can be combined with insulin receptor; promote musculature to the picked-up of glucose, essential amino acid and utilization; accelerate glycolysis; increase gluconeogenesis; taurine is easy to absorb in stomach, has no side effect, and can not bring health hazard factor to Exercise Mechanics; can improve the active MDA content that also effectively reduces of SOD in Exercise Mechanics, in antifatigue, moving, improve the aspects such as locomitivity has significant effect.
Of the present invention for effervescent tablet and the application thereof of supply physical efficiency in time of moving, this effervescent tablet is under the effect of disintegrant, for the preparation to medicine, food and the health products of body fast trace nutrient, can supplement due to motion organism metabolism vigorous and vitamin, the mineral matter of a large amount of consumption; Maintain acid-base balance in body; Promote rapidly fuselage state.This disintegration of tablet is quick, solubility is high, active ingredient is fully utilized, after effervescent tablet is put into drinking water, under the effect of gas-producing disintegrant, at once produce a large amount of bubbles (carbon dioxide), make the rapid disintegration of tablet and thawing, the bubble that disintegration produces also can make tablet rolling up and down in water, accelerate its disintegration and melt utilization rate greatly to improve, can improve the blood-sugar content of the rear body of motion; The blood-sugar content of body while maintaining persistent movement; Delay the generation of body movement fatigue; Reduce the Serum lactic acid content of the rear body of motion; Improve the ability of body endurance exercise, can quickly supplement energy, promote rapidly fuselage state, be applicable to the officers and men of army, various rescue personnel, like players, field exploration or travel staff to supplement rapidly the needs of electrolyte and other nutrient, contribute to improve rapidly body movement and respond.
The specific embodiment
A kind of effervescent tablet for the timely supply physical efficiency of moving of the present embodiment, effervescent tablet raw material comprises following component by weight: oligomeric maltose 50-90 part, citric acid 1-30 part, sodium chloride 0.1-5 part, magnesium carbonate 0.1-5 part, potassium citrate 0.1-5 part, calcium lactate 0.5-5 part, 0.01-1 part vitamin B1,0.01-1 part vitamin B2, ascorbic acid 0.5-5 part, tartaric acid 0.1-5 part, sodium acid carbonate 0.1-5 part, L-arginine 0.1-5 part, taurine 1-20 part, caffeine 0.01-1 part, green-tea extract 1-20 part.
In the present embodiment, effervescent tablet raw material comprises following component by weight: oligomeric maltose 55-85 part, citric acid 5-25 part, sodium chloride 0.5-4 part, magnesium carbonate 0.5-4 part, potassium citrate 0.5-4 part, calcium lactate 0.5-5 part, 0.01-1 part vitamin B1,0.01-1 part vitamin B2, ascorbic acid 0.5-4 part, tartaric acid 0.5-5 part, sodium acid carbonate 0.5-5 part, L-arginine 0.5-5 part, taurine 1-15 part, caffeine 0.01-1 part, green-tea extract 1-18 part.
In the present embodiment, effervescent tablet raw material comprises following component by weight: oligomeric maltose 60-80 part, citric acid 5-20 part, sodium chloride 0.5-2 part, magnesium carbonate 0.5-2 part, potassium citrate 0.5-2 part, calcium lactate 0.5-3 part, 0.01-1 part vitamin B1,0.01-1 part vitamin B2, ascorbic acid 0.5-3 part, tartaric acid 0.5-3 part, sodium acid carbonate 0.5-3 part, L-arginine 0.5-3 part, taurine 1-10 part, caffeine 0.01-1 part, green-tea extract 1-15 part.
In the present embodiment, effervescent tablet raw material comprises following component by weight: 70 parts of oligomeric maltoses, 10 parts of citric acids, 1 part, sodium chloride, 1 part, magnesium carbonate, 1 part of potassium citrate, 1.5 parts, 0.1 part vitamin B1 of calcium lactate, 0.1 part of vitamin B2,1.5 parts, ascorbic acid, 1 part, tartaric acid, 1 part of sodium acid carbonate, 1 part of L-arginine, 5 parts of taurines, 0.5 part of caffeine, 5 parts of green-tea extracts.
In the present embodiment, should can add the carrier that can accept in medical science or bromatology or health care conduct and learning to make preparation for the effervescent tablet of supply physical efficiency in time that moves;
A kind of effervescent tablet for the timely supply physical efficiency of moving of the present embodiment the medicine for the preparation of to body makeup energy, for to body makeup energy health products, for the application of the food to body makeup energy.
By following examples, the present invention is further elaborated.
Embodiment mono-
The present embodiment a kind of for the in time effervescent tablet of supply physical efficiency that moves, effervescent tablet raw material comprises following component by weight: 50 parts of oligomeric maltoses, 1 part of citric acid, 0.1 part, sodium chloride, 0.1 part, magnesium carbonate, 0.1 part of potassium citrate, 0.5 part, 0.01 part vitamin B1 of calcium lactate, 0.01 part of vitamin B2,0.5 part, ascorbic acid, 0.1 part, tartaric acid, 0.1 part of sodium acid carbonate, 0.1 part of L-arginine, 1 part of taurine, 0.01 part of caffeine, 1 part of green-tea extract.
Embodiment bis-
The present embodiment a kind of for the in time effervescent tablet of supply physical efficiency that moves, effervescent tablet raw material comprises following component by weight: 90 parts of oligomeric maltoses, 30 parts of citric acids, 5 parts, sodium chloride, 5 parts, magnesium carbonate, 5 parts of potassium citrates, 5 parts, 1 part vitamin B1 of calcium lactate, 1 part of vitamin B2,5 parts, ascorbic acid, 5 parts, tartaric acid, 5 parts of sodium acid carbonates, 5 parts of L-arginines, 20 parts of taurines, 1 part of caffeine, 20 parts of green-tea extracts.
Embodiment tri-
The effervescent tablet raw material of the present embodiment comprises following component by weight: 55 parts of oligomeric maltoses, 5 parts of citric acids, 0.5 part, sodium chloride, 0.5 part, magnesium carbonate, 0.5 part of potassium citrate, 0.5 part, 0.01 part vitamin B1 of calcium lactate, 0.01 part of vitamin B2,0.5 part, ascorbic acid, 0.5 part, tartaric acid, 0.5 part of sodium acid carbonate, 0.5 part of L-arginine, 1 part of taurine, 0.01 part of caffeine, 1 part of green-tea extract.
Embodiment tetra-
The effervescent tablet raw material of the present embodiment comprises following component by weight: 85 parts of oligomeric maltoses, 25 parts of citric acids, 4 parts, sodium chloride, 4 parts, magnesium carbonate, 4 parts of potassium citrates, 5 parts, 1 part vitamin B1 of calcium lactate, 1 part of vitamin B2,4 parts, ascorbic acid, 5 parts, tartaric acid, 5 parts of sodium acid carbonates, 5 parts of L-arginines, 15 parts of taurines, 1 part of caffeine, 18 parts of green-tea extracts.
Embodiment five
The effervescent tablet raw material of the present embodiment comprises following component by weight: 60 parts of oligomeric maltoses, 5 parts of citric acids, 0.5 part, sodium chloride, 0.5 part, magnesium carbonate, 0.5 part of potassium citrate, 0.5 part, 0.01 part vitamin B1 of calcium lactate, 0.01 part of vitamin B2,0.5 part, ascorbic acid, 0.5 part, tartaric acid, 0.5 part of sodium acid carbonate, 0.5 part of L-arginine, 1 part of taurine, 0.01 part of caffeine, 1 part of green-tea extract.
Embodiment six
Effervescent tablet raw material in the present embodiment comprises following component by weight: 80 parts of oligomeric maltoses, 20 parts of citric acids, 2 parts, sodium chloride, 2 parts, magnesium carbonate, 2 parts of potassium citrates, 3 parts, 1 part vitamin B1 of calcium lactate, 1 part of vitamin B2,3 parts, ascorbic acid, 3 parts, tartaric acid, 3 parts of sodium acid carbonates, 3 parts of L-arginines, 10 parts of taurines, 1 part of caffeine, 15 parts of green-tea extracts.
Embodiment seven
The effervescent tablet raw material of the present embodiment comprises following component by weight: 70 parts of oligomeric maltoses, 10 parts of citric acids, 1 part, sodium chloride, 1 part, magnesium carbonate, 1 part of potassium citrate, 1.5 parts, 0.1 part vitamin B1 of calcium lactate, 0.1 part of vitamin B2,1.5 parts, ascorbic acid, 1 part, tartaric acid, 1 part of sodium acid carbonate, 1 part of L-arginine, 5 parts of taurines, 0.5 part of caffeine, 5 parts of green-tea extracts.
Embodiment eight
The effervescent tablet raw material of the present embodiment comprises following component by weight: 50 parts of oligomeric maltoses, 10 parts of citric acids, 0.1 part, sodium chloride, 1 part, magnesium carbonate, 0.1 part of potassium citrate, 1.5 parts, 0.01 part vitamin B1 of calcium lactate, 0.1 part of vitamin B2,0.5 part, ascorbic acid, 1 part, tartaric acid, 0.1 part of sodium acid carbonate, 1 part of L-arginine, 1 part of taurine, 0.5 part of caffeine, 1 part of green-tea extract.
Embodiment nine
The effervescent tablet raw material of the present embodiment comprises following component by weight: 70 parts of oligomeric maltoses, 1 part of citric acid, 1 part, sodium chloride, 0.1 part, magnesium carbonate, 1 part of potassium citrate, 0.5 part, 0.1 part vitamin B1 of calcium lactate, 0.01 part of vitamin B2,1.5 parts, ascorbic acid, 0.1 part, tartaric acid, 1 part of sodium acid carbonate, 0.1 part of L-arginine, 5 parts of taurines, 0.01 part of caffeine, 5 parts of green-tea extracts.
After each component of above-described embodiment is mixed according to routine techniques means granulate, oven dry, compressing tablet obtain effervescent tablet of the present invention.
In above-described embodiment, for the effervescent tablet of supply physical efficiency in time that moves, can add the carrier that can accept in medical science or bromatology or health care conduct and learning to make preparation.
In above-described embodiment for the timely effervescent tablet of supply physical efficiency of moving can be applied to for the preparation of the medicine to body makeup energy, for to body makeup energy health products, for the food to body makeup energy.
For checking the effervescent tablet for the timely supply physical efficiency of moving of the present invention to maintain effect to large intensity persistent movement officers and men physical efficiency, carried out following experiment.
1, tested material: take embodiment seven as laboratory sample, with the isocaloric syrup of equal-volume sample in contrast.
2, study subject: run achievements and in conjunction with treadmill physical stamina test result by recording pulse, recent 5 kilometers, filter out 16 people that physical state approaches and participate in test as study subject, be divided at random test group and control group, every group of 8 people.First 7 days of on-test,, 16 study subjects are unified centralized management, the unified daily schedule, arrange training and the motion of equality strength every day.During this time, in strict accordance with same heat standard supply meals, except freely drinking water, do not allow to take food any other food or nutriment, no smoking and drink.Test group is early drunk laboratory sample 600ml after the meal every day, and control group is drunk equivalent control sample, continuous 7 days.
3, test method
Formal test day, getting study subject early drinks after laboratory sample or control sample 35 minutes after the meal in accordance with regulations, carry out 5 kilometers of curfews, according to recent 5 kilometers of study subject, run achievement, requirement completed in 24 minutes, thereby to avoid each study subject exercise intensity result of the test of impact that has big difference, the achievement of every study subject of accurate recording.Before motion, immediate postexercise, motion adopt respectively and refer to that blood surveys blood sugar and blood lactic acid for latter 3 minutes, 5 minutes, 15 minutes and 30 minutes.Wherein blood sugar adopts
One touch Ultra blood glucose meter is measured, and blood lactic acid adopts YSI1500 lactic acid instrument to measure.
4, result of the test
4.1 change of blood sugar situations
Before and after the test of table 1 study subject, blood sugar level changes (mmol/L)
With the control group comparison of same time point, P<0.05; B: compare P<0.05 before testing with self.
As shown in table 1, the blood sugar level of control group and test group there was no significant difference before motion.After motion 3,5,15 and 30 minutes time, the blood sugar level of test group is all higher than the value of corresponding time point control group, and difference has statistical significance (P<0.05); On the other hand, test group is until move latter 30 minutes time, though blood sugar level decline to some extent, not remarkable; And control group is after motion, blood sugar level declines obviously, and the blood sugar level of moving latter 5 minutes is starkly lower than (P<0.05) before motion.
Above result shows, when effervescent tablet maintains persistent movement, blood sugar level is respond well, points out this product to have the tired effect occurring of delayed motion.
4.2 blood lactic acid change
In table 2 study subject process of the test, blood lactate level changes (mmol/L)
With the control group comparison of same time point, P<0.05.
As shown in table 2, blood lactate level there was no significant difference before motion of control group and test group.After motion 5,15 and 30 minutes time, the blood lactate level of test group is all lower than the value of corresponding time point control group, and difference has statistical significance (P<0.05); Above result shows, compares with simple syrup, and after effervescent tablet removing high-intensity exercise, blood lactic acid is respond well, contributes to slow down sense of fatigue, promotes the physical efficiency recovery after high-intensity exercise.
4.35 kilometers are run achievement
Before and after the test of table 3 study subject, 5 kilometers are run achievement (min)
Relatively front with test, P<0.05.
As shown in table 3,5 kilometers of control group and test group are run achievement there was no significant difference before test; 5 kilometers of race achievement test front and back of control group are without significant change.And through within continuous 7 days, taking effervescent tablet, 5 kilometers of race required times of test group are tested front minimizing, and difference has statistical significance (P<0.05).Above result shows, effervescent tablet contributes to improve the ability of body endurance exercise.
All the other embodiment acquired results and upper without substantive difference repeat no more herein.
Antifatigue effect to energy composition of the present invention is analyzed:
This test is through the agreement of ethics meeting, and 28 volunteers have participated in this double blinding, random, the experiment of parallel control.1. before experiment, volunteer is arranged to test height, body weight, body-mass index, body fat content percentage, and maximal oxygen uptake.MONARK839E cycle ergometer test for maximal oxygen uptake, all the other use Biospace Inbody720 to detect.If there is following situation, will be excluded from this experiment.1, smoker 2, have chronic disease history 3, take nutritious supplementary pharmaceutical.What every volunteer was told that this experiment likely occurs is not symptom, and has signed Informed Consent Form.To laboratory, be familiar with two stages and the experiment of test and ask for the instrument of use, informed them before test is not carried out any strenuous exercise for first 72 hours and the collected meals situation of 3 days.All experiments all complete at MONARK839E cycle ergometer.
Stage one:
The Astrand pattern of the MONARK839E cycle ergometer that the assessment of maximal oxygen uptake is used.What the detection of heart rate was used is heart rate telemetering system, and pectoral girdle is tied up in front, is close to the position that V5 leads.Volunteer is required first to carry out to carry out under the intensity of 80W two minutes warm-up, has a rest 5 minutes, and the Abstrand that then carries out the duration sub-peak load of 6 minutes tests, to reach a stable heart rate level.According to the value of the maximal oxygen uptake recording, crowd is divided into 3 large group: GOOD group (VO2max>52ml.min-1.kg-1) AVERAGE group (43ml.min-1.kg-1<VO2max<52ml.mi n-1.kg-1); POOR group (VO2max<43ml.min-1.kg-1).Each group, volunteer is made into two subgroups by random average mark again, EB1 and EB2, the energy composition of eating respectively embodiment 1 and embodiment 2, one day 2 times, eats one week.
Stage two:
The assessment that power exhausts the time also completes at MONARK839E cycle ergometer.Volunteer warms up 3 minutes under 80W intensity, has a rest 5 minutes, and test formally starts.The load starting is most at 80W, then increase 20W per minute until power exhaust.The rhythm and pace of moving things of stepping bicycle remains on 70rpm.When volunteer is when under speech is encouraged, the rhythm and pace of moving things can not keep 70rpm, the EOT end of test.The power time of exhausting is recorded to last second.The same method of heart rate monitoring and a use.All experiments are in certain height above sea level, and temperature is at 18 to 20 degree, and humidity, in 40% to 60% room, is tested the same day, and volunteer is apprised of 7: 30 and arrives on an empty stomach experiment place, and calmness takes a load off one's feet 15 minutes.Blood sample is taked after finishing with test before warming up immediately, adopts respectively and refers to blood and venous blood.
Result of the test:
Crowd characteristic:
Each large group and subgroup, crowd is at the age for each group, height, and body-mass index, body fat percentage does not have obvious difference.
Table 4 volunteer's essential characteristic
Power exhausts the time
In order to assess embodiment 1 and embodiment 2 in 3 groups of varying level volunteers' performance, firmly the time of exhausting is assessed for we.In POOR group and GOOD group, two subgroups do not have obvious difference (P>0.05).But, in AVERAGE group, between two subgroups, there is obvious difference (p=0.012), EB2 group successful is better than EB1 group.
Table 5 power exhausts the time (min)
Group EB1 EB2
Poor 7.87±1.53 7.23±1.18
Average 9.40±0.77 7.99±0.81
Good 9.77±1.27 9.61±0.67
Reached for 75% maximum heart rate time
Table 6 reached for 75% maximum heart rate time
Group EB2 EB1
Poor 254.2±89.70 285.8±68.53
Average 275±63.17 296.17±96.03
Good 346.67±29.7 364.00±16.10
Blood sample is analyzed
The value of blood lactic acid can be used for assessing endurance, and the value of blood lactic acid and maximal oxygen uptake height correlation, and the value of blood lactic acid is subject to again the impact of meals at ordinary times, and high carbohydrate meals can cause increasing of blood lactic acid.The embodiment 1 of this experiment and 2 impacts for blood lactic acid see the following form.
Blood Lactate before and after table 7 experiment
Other formulas of composition of the present invention can reach good antifatigue effect equally.Above-mentioned test shows, composition of the present invention is not only applicable to physical efficiency recovery, is not only particularly suitable for the needs that quickly supplement energy after army's high pressure training, and mental recovery is had to very significantly effect, can impel muscle cell impaired in motion to recover rapidly, reduce myoglobins value in blood, accelerate the elimination of muscular fatigue, can stabilizing blood sugar, blue-collar persistence and endurance have been guaranteed, can promote fat metabolism, reduce the accumulation of subcutaneous fat, there is the effect of antifatigue.
Finally explanation is, above embodiment is only unrestricted in order to technical scheme of the present invention to be described, although the present invention is had been described in detail with reference to preferred embodiment, those of ordinary skill in the art is to be understood that, can modify or be equal to replacement technical scheme of the present invention, and not departing from aim and the scope of technical solution of the present invention, it all should be encompassed in the middle of claim scope of the present invention.

Claims (6)

1. for the effervescent tablet for supply physical efficiency in time that moves, it is characterized in that: effervescent tablet raw material comprises following component by weight: oligomeric maltose 50-90 part, citric acid 1-30 part, sodium chloride 0.1-5 part, magnesium carbonate 0.1-5 part, potassium citrate 0.1-5 part, calcium lactate 0.5-5 part, 0.01-1 part vitamin B1,0.01-1 part vitamin B2, ascorbic acid 0.5-5 part, tartaric acid 0.1-5 part, sodium acid carbonate 0.1-5 part, L-arginine 0.1-5 part, taurine 1-20 part, caffeine 0.01-1 part, green-tea extract 1-20 part.
2. according to claim 1 for the effervescent tablet of supply physical efficiency in time that moves, it is characterized in that: effervescent tablet raw material comprises following component by weight: oligomeric maltose 55-85 part, citric acid 5-25 part, sodium chloride 0.5-4 part, magnesium carbonate 0.5-4 part, potassium citrate 0.5-4 part, calcium lactate 0.5-5 part, 0.01-1 part vitamin B1,0.01-1 part vitamin B2, ascorbic acid 0.5-4 part, tartaric acid 0.5-5 part, sodium acid carbonate 0.5-5 part, L-arginine 0.5-5 part, taurine 1-15 part, caffeine 0.01-1 part, green-tea extract 1-18 part.
3. according to claim 2 for the effervescent tablet of supply physical efficiency in time that moves, it is characterized in that: effervescent tablet raw material comprises following component by weight: oligomeric maltose 60-80 part, citric acid 5-20 part, sodium chloride 0.5-2 part, magnesium carbonate 0.5-2 part, potassium citrate 0.5-2 part, calcium lactate 0.5-3 part, 0.01-1 part vitamin B1,0.01-1 part vitamin B2, ascorbic acid 0.5-3 part, tartaric acid 0.5-3 part, sodium acid carbonate 0.5-3 part, L-arginine 0.5-3 part, taurine 1-10 part, caffeine 0.01-1 part, green-tea extract 1-15 part.
4. according to claim 3 for the in time effervescent tablet of supply physical efficiency that moves, it is characterized in that: effervescent tablet raw material comprises following component by weight: 70 parts of oligomeric maltoses, 10 parts of citric acids, 1 part, sodium chloride, 1 part, magnesium carbonate, 1 part of potassium citrate, 1.5 parts, 0.1 part vitamin B1 of calcium lactate, 0.1 part of vitamin B2,1.5 parts, ascorbic acid, 1 part, tartaric acid, 1 part of sodium acid carbonate, 1 part of L-arginine, 5 parts of taurines, 0.5 part of caffeine, 5 parts of green-tea extracts.
5. according to the arbitrary described effervescent tablet for the timely supply physical efficiency of moving of claim 1-4, it is characterized in that: should can add the carrier that can accept in medical science or bromatology or health care conduct and learning to make preparation for the effervescent tablet of supply physical efficiency in time that moves.
The arbitrary described effervescent tablet for the supply physical efficiency in time of moving of a claim 1-4 the medicine for the preparation of to body makeup energy, for to body makeup energy health products, for the application of the food to body makeup energy.
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CN104366647A (en) * 2014-10-20 2015-02-25 北京康比特体育科技股份有限公司 Composition capable of enhancing durability and relieving fatigue and preparation method of composition
CN104366647B (en) * 2014-10-20 2016-09-28 北京康比特体育科技股份有限公司 A kind of stamina intensifying, composition for relieving fatigue and preparation method thereof
CN107028976A (en) * 2016-02-03 2017-08-11 孙华燕 Potassium citrate effervescent tablet mends potassium medicine and preparation method thereof
CN109527325A (en) * 2018-11-20 2019-03-29 江苏汉典生物科技股份有限公司 A kind of sports type effervescent tablet and preparation method thereof
CN109430669A (en) * 2018-12-25 2019-03-08 江苏艾兰得营养品有限公司 Improve the effervesce tablet preparation and preparation method thereof of nutrition needed for endurance supplement moves
CN110521908A (en) * 2019-09-02 2019-12-03 成都六然医疗科技有限公司 A kind of potassium citrate effervescent tablet anti-trioxypurine composition
CN110521908B (en) * 2019-09-02 2020-10-02 成都六然医疗科技有限公司 Oral administration method of potassium citrate effervescent tablets for reducing uric acid
EP4076004A4 (en) * 2019-12-20 2023-12-27 Bubble Sip, LLC Carbonated drink and method of making same
CN111592086A (en) * 2020-06-01 2020-08-28 长沙拜特生物科技研究所有限公司 Vitamin C effervescent tablet for improving water quality and preparation method thereof
CN112471507A (en) * 2020-10-23 2021-03-12 中国人民解放军陆军军医大学 Electrolyte supplement composition for plateau environment exercise training

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Application publication date: 20140723