CN103931953B - A kind of feed, Chinese medicine composition and preparation method for preventing and treating bowel oedema disease - Google Patents
A kind of feed, Chinese medicine composition and preparation method for preventing and treating bowel oedema disease Download PDFInfo
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- CN103931953B CN103931953B CN201410193519.6A CN201410193519A CN103931953B CN 103931953 B CN103931953 B CN 103931953B CN 201410193519 A CN201410193519 A CN 201410193519A CN 103931953 B CN103931953 B CN 103931953B
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Abstract
The invention discloses a kind of feed, Chinese medicine composition and preparation method for preventing and treating bowel oedema disease, its feed comprise Chinese medicine additive, montmorillonite, brewer's yeast, trace element chelated dose, corn, hay, bacillus, Chinese medicine additive comprises Divine Comedy, rice bud, fructus amomi, the bighead atractylodes rhizome, fevervine, the root of large-flowered skullcap, honeysuckle, mountain on the other way round disappear, asafoetide, raddle, caulis bambusae in taenian, yncaria stem with hooks, rhizoma Gastrodiae, rhizoma arisaematis, borneol, bluish dogbane, selfheal, akebi, umbellate pore furgus, rhizoma alismatis, Radix Glycyrrhizae, Herba Andrographitis, rhizome of cyrtomium, Paris polyphylla, Oroxylum indicum, Root of Loping Thistle, play both sides of the street and shoulder plate and return.The invention has the beneficial effects as follows: feed provided by the invention contains Chinese medicine additive, there is strengthening the spleen and stomach, clearing heat and detoxicating function, prevent and treat bowel oedema disease have clinical effectiveness obviously, have no side effect, cheap, simple for production and can improve the immunity of organisms of ill pig and the advantage of resistance against diseases, while also can play certain health-care effect to the consumer eating this type of pork.
Description
Technical field
The present invention relates to technical field of animal, particularly a kind of feed, Chinese medicine composition and preparation method for preventing and treating bowel oedema disease.
Background technology
Bowel oedema disease is also known as colitoxemia, edema disease, gastric edema.Be the disease of a kind of acute, lethal of piggy, it is characterized by coat of the stomach and oedema occurs at some other position.
This disease mainly betides delactational piglets, and little of age a few days, there is generation at greatly to 4 monthly age.The piglet that growth is fast, body condition is healthy and strong is the most common, and modest piglet occurs less.The sow that carries disease germs is propagated to piglet, in endemic conditions, is often limited to the piglet of some pig farm and some nest.Diet method changes, and feed is single, climate change, the water after contaminated, environment, and apparatus etc. all can cause the Probability of this disease to increase and exacerbation of symptoms.This disease all can occur throughout the year, but is more common in spring and autumn.As the piglet of yellow dysentery of coming into being, generally there is not this disease.
Clinical symptoms
Sick pig sudden onset, spirit is depressed, poor appetite, mouth stream foam, and body temperature, without significant change, has laxativeness in 1-2 days, rear constipation before sick.Heartbeat quickly, is breathed just fast and shallow, dark slowly afterwards.The sleeping ground of happiness, muscular tremor, twitch frequently, and major beat swimming shape, groan, haunch when standing, shakes.Forelimb is as benumbed, then astasia, hindlimb paralysis, then can not stand.Weakness of limbs during walking, incoordination, gait waves shakiness, blindly advances or makes circular motion.Oedema is the characteristic symptom of this disease, be common in face, eyelid, conjunctiva, gums, neck, belly subcutaneous.The sick pig had does not have the change of oedema.The only a few hours that the course of disease is short, be generally 1-2 days, also have and reach more than 7 days.Case fatality rate about 90%.
Mainly sudden onset, body temperature is not high, quadruped locomotion obstacle, and rear quarters is unable, waves and incoordination; The sick pig had does circular motion or blindly disorderly punching, suddenly violent body wash-ahead; When various stimulation or seizure, the scream of touching, calls hoarse, falls down to the ground, and four limbs are disorderly dynamic, shape of seemingly swimming; The sick common face of pig, palpebral edema, severe one is extended down to face, neck, and head becomes fat.
Doctor trained in Western medicine is prevented and treated bowel oedema disease and be there is no special effective therapy to this disease at present, prevents this sick key to be to improve feeding and management, and feed nutrition is wanted comprehensively, and protein can not be too high.Drug therapy early stage results is good, and the later stage is generally invalid.
Chinese traditional treatment bowel oedema disease has advantageous clinical efficacy.The traditional Chinese medical science carries out dialectical treatmert on the basis of Overall View, and for the disease instant effect of same class card, short treating period, clinical effectiveness is obvious.Further, pure natural, to have no side effect, drug residue free, medicinal material cost price is cheap, simple for production, can improve immunity of organisms and the resistance against diseases of ill pig, also can play certain health-care effect to the consumer of this type of pork edible simultaneously.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of feed comprising Chinese medicine composition for preventing and treating bowel oedema disease, adopt the feed containing this Chinese medicine composition can overcome the defect of prior art Chinese and Western medicine and Chinese medicine, to the treatment of the pig suffering from bowel oedema disease, there is strengthening the spleen and stomach, clearing heat and detoxicating function, and instant effect, short treating period, curative effect develop immunity to drugs really, not easily, not easily recurrence, few side effects, livestock products drug residue are low, inexpensive, the advantage that is conducive to person poultry safety.
In order to realize foregoing invention object, the invention provides a kind of feed for preventing and treating bowel oedema disease, comprise Chinese medicine additive, montmorillonite, brewer's yeast, trace element chelated dose, corn, hay, bacillus, described Chinese medicine additive comprises Divine Comedy, rice bud, fructus amomi, the bighead atractylodes rhizome, fevervine, the root of large-flowered skullcap, honeysuckle, mountain on the other way round disappear, asafoetide, raddle, caulis bambusae in taenian, yncaria stem with hooks, rhizoma Gastrodiae, rhizoma arisaematis, borneol, bluish dogbane, selfheal, akebi, umbellate pore furgus, rhizoma alismatis, Radix Glycyrrhizae, Herba Andrographitis, rhizome of cyrtomium, Paris polyphylla, Oroxylum indicum, Root of Loping Thistle, play both sides of the street and shoulder plate and return.
In described Chinese medicine additive, the ratio of weight and number of each bulk drug is: Divine Comedy 16-35 weight portion, rice bud 11-25 weight portion, fructus amomi 19-32 weight portion, bighead atractylodes rhizome 23-34 weight portion, fevervine 10-25 weight portion, root of large-flowered skullcap 20-36 weight portion, honeysuckle 28-40 weight portion, mountain on the other way round disappears 14-26 weight portion, asafoetide 10-24 weight portion, raddle 14-28 weight portion, caulis bambusae in taenian 15-30 weight portion, yncaria stem with hooks 7-21 weight portion, rhizoma Gastrodiae 21-35 weight portion, rhizoma arisaematis 3-8 weight portion, borneol 16-28 weight portion, bluish dogbane 20-35 weight portion, selfheal 9-23 weight portion, akebi 28-40 weight portion, umbellate pore furgus 18-30 weight portion, rhizoma alismatis 15-28 weight portion, Radix Glycyrrhizae 12-24 weight portion, Herba Andrographitis 21-34 weight portion, rhizome of cyrtomium 5-13 weight portion, Paris polyphylla 8-21 weight portion, Oroxylum indicum 12-28 weight portion, Root of Loping Thistle 25-39 weight portion, play both sides of the street 18-34 weight portion and shoulder plate and return 9-27 weight portion.
In described feed, the weight portion of each component is: described Chinese medicine additive 12-16 weight portion, trace element chelated dose of 2-6 weight portion, sugared brewer's yeast 0.2-0.7 weight portion, corn 46-67 weight portion, hay 41-65 weight portion, bacillus 0.4-0.9 weight portion, montmorillonite 3-5 weight portion.
Described bacillus comprises one or both mixing in bacillus subtilis and bacillus licheniformis.
Described trace element chelated dose comprises hemoglobin, cytochrome oxidase and Cobastab
12.
In described Chinese medicine additive, the weight portion of each bulk drug also can be: Divine Comedy 19-31 weight portion, rice bud 13-22 weight portion, fructus amomi 21-30 weight portion, bighead atractylodes rhizome 25-32 weight portion, fevervine 13-21 weight portion, root of large-flowered skullcap 22-33 weight portion, honeysuckle 30-38 weight portion, mountain on the other way round disappears 16-24 weight portion, asafoetide 12-22 weight portion, raddle 16-25 weight portion, caulis bambusae in taenian 18-27 weight portion, yncaria stem with hooks 9-18 weight portion, rhizoma Gastrodiae 23-33 weight portion, rhizoma arisaematis 3-7 weight portion, borneol 19-26 weight portion, bluish dogbane 22-33 weight portion, selfheal 11-20 weight portion, akebi 30-37 weight portion, umbellate pore furgus 20-28 weight portion, rhizoma alismatis 17-26 weight portion, Radix Glycyrrhizae 14-21 weight portion, Herba Andrographitis 23-32 weight portion, rhizome of cyrtomium 5-11 weight portion, Paris polyphylla 10-18 weight portion, Oroxylum indicum 14-25 weight portion, Root of Loping Thistle 27-37 weight portion, play both sides of the street 20-31 weight portion and shoulder plate 11-24 weight portion.
In described Chinese medicine additive, the weight portion of each bulk drug can be again: Divine Comedy 21-28 weight portion, rice bud 14-21 weight portion, fructus amomi 23-28 weight portion, bighead atractylodes rhizome 26-31 weight portion, fevervine 15-20 weight portion, root of large-flowered skullcap 24-30 weight portion, honeysuckle 31-37 weight portion, mountain on the other way round disappears 17-22 weight portion, asafoetide 14-20 weight portion, raddle 18-23 weight portion, caulis bambusae in taenian 19-25 weight portion, yncaria stem with hooks 10-17 weight portion, rhizoma Gastrodiae 25-31 weight portion, rhizoma arisaematis 3-6 weight portion, borneol 19-24 weight portion, bluish dogbane 22-29 weight portion, selfheal 11-18 weight portion, akebi 32-37 weight portion, umbellate pore furgus 21-27 weight portion, rhizoma alismatis 17-23 weight portion, Radix Glycyrrhizae 14-18 weight portion, Herba Andrographitis 25-31 weight portion, rhizome of cyrtomium 5-9 weight portion, Paris polyphylla 10-16 weight portion, Oroxylum indicum 16-24 weight portion, Root of Loping Thistle 28-36 weight portion, play both sides of the street 21-28 weight portion and shoulder plate and return 13-21 weight portion.
The present invention also provides a kind of preparation method of the feed for preventing and treating bowel oedema disease, comprises the following steps:
The first step, corn, hay are dropped in mixer in proportion and mixes, adding water, controlling the content of moisture in mixture is 59%-82%, stir, after add brewer's yeast, bacillus in proportion, mixed material is added in horizental silo, by the material compacting mixed, cover tightly, cause internal batch anaerobic environment, at the temperature bottom fermentation 35-40 days of 19 DEG C-30 DEG C, rear acquisition fermented product, carries out drying by fermentation material, obtain the solid fermentation product of moisture below 7%, be ground into powder;
Second step, described montmorillonite adopts micronizer to be ground into the ultra-micro powder of 16-31 μm;
3rd step, each bulk drug in described Chinese medicine additive is mixed in proportion, adding relative to the determining alcohol of its quality 3 times is subsequently the ethanol of 73-86%, add hot reflux 2 hours, filter, by filtered fluid at-1.0 DEG C refrigerated overnight, again filter, decompression recycling ethanol, is ground into powder, obtains Chinese medicine additive powder;
4th step, mixes the Chinese medicine additive powder of the montmorillonite ultra-micro powder of the fermented product powder of first step acquisition, second step acquisition, the 3rd step acquisition and trace element chelated dose in proportion, namely obtains described feed.
Present invention also offers a kind of Chinese medicine composition for preventing and treating bowel oedema disease, Chinese medicine composition comprises the bulk drug of following ratio of weight and number: Divine Comedy 16-35 weight portion, rice bud 11-25 weight portion, fructus amomi 19-32 weight portion, bighead atractylodes rhizome 23-34 weight portion, fevervine 10-25 weight portion, root of large-flowered skullcap 20-36 weight portion, honeysuckle 28-40 weight portion, mountain on the other way round disappears 14-26 weight portion, asafoetide 10-24 weight portion, raddle 14-28 weight portion, caulis bambusae in taenian 15-30 weight portion, yncaria stem with hooks 7-21 weight portion, rhizoma Gastrodiae 21-35 weight portion, rhizoma arisaematis 3-8 weight portion, borneol 16-28 weight portion, bluish dogbane 20-35 weight portion, selfheal 9-23 weight portion, akebi 28-40 weight portion, umbellate pore furgus 18-30 weight portion, rhizoma alismatis 15-28 weight portion, Radix Glycyrrhizae 12-24 weight portion, Herba Andrographitis 21-34 weight portion, rhizome of cyrtomium 5-13 weight portion, Paris polyphylla 8-21 weight portion, Oroxylum indicum 12-28 weight portion, Root of Loping Thistle 25-39 weight portion, play both sides of the street 18-34 weight portion and shoulder plate and return 9-27 weight portion.
The preparation method of described Chinese traditional medicine composition composition powders comprises:
Step one, all bulk drugs are dropped in proportion in mixer stir, mixing, pulverize in rear feeding pulverizer, the Chinese medicine composition after pulverizing is loaded in multi-function extractor, add relative to its quality 5-7 times amount water, boil 2-4 hour, steam pressure is 0.6-1Mpa process, filter, obtain the first filtered fluid and filter residue;
Step 2, the filter residue of acquisition added again relative to its quality 5-7 times amount water, boil 2-4 hour, steam pressure is 0.6Mpa-1Mpa process, filter and obtain the second filtered fluid and filter residue;
Step 3, the first filtered fluid and the second filtered fluid merged, concentrated removing moisture, obtains and gets dry extract, and adopts super-fine powder mill to pulverize, is crushed to less than 30 μm, obtain Chinese medicine additive powder.
The beneficial effect that technical scheme provided by the invention is brought is: feed provided by the invention contains Chinese medicine additive, there is strengthening the spleen and stomach, clearing heat and detoxicating function, in anti-treatment bowel oedema disease, there is instant effect, short treating period, clinical effectiveness obviously, have no side effect, cheap, simple for production and can improve the immunity of organisms of ill pig and the advantage of resistance against diseases, while also can play certain health-care effect to the consumer eating this type of pork.
Detailed description of the invention
Chinese veterinarian thinks the operation of water liquid, and depend on the promotion of gas, the liter namely depending on temper is transferred, and the Xuan Jiangtong of lung qi adjusts, the promotion of the motive, kidney qi evaporate folding.These functions are normal, then three burnt performances certainly show disrespect on effect, and functioning of bladder passes unimpeded, normal urination, can maintain the metabolism of normal water liquid.Otherwise if because of damp and hot heresy of catching cold, the wet dipping of water, sore is contaminated, and improper diet and overtiredness, weakness due to chronic disease etc. cause above-mentioned visceral dysfunction, and three Jiao certainly show disrespect on mistake department, and functioning of bladder is unfavorable, and water retention in body, spreads unchecked skin, can send out as oedema.
Therefore, the present invention treats bowel oedema disease, with strengthening the spleen and stomach, clearing heat and detoxicating is primary treatment principle, selects prescription: Divine Comedy, rice bud, fructus amomi, the bighead atractylodes rhizome, fevervine, the root of large-flowered skullcap, honeysuckle, mountain on the other way round disappear, asafoetide, raddle, caulis bambusae in taenian, yncaria stem with hooks, rhizoma Gastrodiae, rhizoma arisaematis, borneol, bluish dogbane, selfheal, akebi, umbellate pore furgus, rhizoma alismatis, Radix Glycyrrhizae, Herba Andrographitis, rhizome of cyrtomium, Paris polyphylla, Oroxylum indicum, Root of Loping Thistle, play both sides of the street and shoulder plate and return.
The invention provides a kind of feed for preventing and treating bowel oedema disease, comprise Chinese medicine additive, montmorillonite, brewer's yeast, trace element chelated dose, corn, hay, bacillus, described Chinese medicine additive comprises Divine Comedy, rice bud, fructus amomi, the bighead atractylodes rhizome, fevervine, the root of large-flowered skullcap, honeysuckle, mountain on the other way round disappear, asafoetide, raddle, caulis bambusae in taenian, yncaria stem with hooks, rhizoma Gastrodiae, rhizoma arisaematis, borneol, bluish dogbane, selfheal, akebi, umbellate pore furgus, rhizoma alismatis, Radix Glycyrrhizae, Herba Andrographitis, rhizome of cyrtomium, Paris polyphylla, Oroxylum indicum, Root of Loping Thistle, play both sides of the street and shoulder plate and return.
In Chinese medicine additive, the ratio of weight and number of each bulk drug is: Divine Comedy 16-35 weight portion, rice bud 11-25 weight portion, fructus amomi 19-32 weight portion, bighead atractylodes rhizome 23-34 weight portion, fevervine 10-25 weight portion, root of large-flowered skullcap 20-36 weight portion, honeysuckle 28-40 weight portion, mountain on the other way round disappears 14-26 weight portion, asafoetide 10-24 weight portion, raddle 14-28 weight portion, caulis bambusae in taenian 15-30 weight portion, yncaria stem with hooks 7-21 weight portion, rhizoma Gastrodiae 21-35 weight portion, rhizoma arisaematis 3-8 weight portion, borneol 16-28 weight portion, bluish dogbane 20-35 weight portion, selfheal 9-23 weight portion, akebi 28-40 weight portion, umbellate pore furgus 18-30 weight portion, rhizoma alismatis 15-28 weight portion, Radix Glycyrrhizae 12-24 weight portion, Herba Andrographitis 21-34 weight portion, rhizome of cyrtomium 5-13 weight portion, Paris polyphylla 8-21 weight portion, Oroxylum indicum 12-28 weight portion, Root of Loping Thistle 25-39 weight portion, play both sides of the street 18-34 weight portion and shoulder plate and return 9-27 weight portion.
Wherein, Divine Comedy is pungent loose to help digestion with row, sweet temperature spleen benefiting and stimulating the appetite and middle antidiarrheal, can bring down a fever again; Rice bud is aid digestion and the gas that do not injure one's stomach, with fructus amomi, the bighead atractylodes rhizome, Radix Glycyrrhizae compatibility with using; Fevervine food digesting stomach fortifying, preventing phlegm from forming and stopping coughing, clearing heat and detoxicating, pain relieving, with the root of large-flowered skullcap, honeysuckle compatibility with using; Mountain on the other way round disappears stomach invigorating, regulating qi-flowing for relieving pain, with fructus amomi compatibility with using; Asafoetide returns liver taste warp, is equal to uses with the bighead atractylodes rhizome; Raddle is calming the liver, inverse, cooling blood and hemostasis falls in important city, with caulis bambusae in taenian, Root of Loping Thistle compatibility with using; Bluish dogbane can suppressing liver-YANG, heat-clearing, diuresis, with yncaria stem with hooks, selfheal, akebi, umbellate pore furgus, rhizoma alismatis compatibility with using; Rhizoma Gastrodiae can relieving convulsion and spasm, suppressing liver-YANG, with yncaria stem with hooks, the bighead atractylodes rhizome, rhizoma arisaematis compatibility with using; Borneol is had one's ideas straightened out inducing resuscitation, clearing away heat to and alleviating pain; Herba Andrographitis, rhizome of cyrtomium, Paris polyphylla, Oroxylum indicum compatibility can clearing heat and detoxicating, cooling blood and hemostasis, detumescence; Play both sides of the street dispelling, collateral-activating, and Li Shui stimulates the menstrual flow; Shouldering plate returns clearing heat and detoxicating; Inducing diuresis and reducing edema; Radix Glycyrrhizae coordinating the drug actions of a prescription.
The pharmacology of described each bulk drug is as follows:
Divine Comedy: nature and flavor are bitter, temperature.Return spleen, stomach, large intestine channel.Can reinforcing spleen to promote digestion, regulating QI to expel dampness, induces sweat.Cure the wound the food feeling of stuffiness in chest, and stomachache is vomited and diarrhoea, dysentery, cold headache, and children's hinders hungry mistake and satisfies.
Rice bud: nature and flavor are sweet is flat.Return spleen, stomach warp, Liver Channel.There is promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite, move back effect of newborn dissipate-swelling.Cure mainly dyspepsia not disappear, abdominal distention, insufficiency of the spleen food is few, and newborn sweat smoulders, swollen breasts, and women weans.
Fructus amomi: taste is pungent, warm in nature.Return the spleen channel, stomach warp, kidney channel.Function dampness elimination is whetted the appetite, warming spleen and stopping diarrha, regulates the flow of vital energy antiabortive.For turbi damp obstructing in middle-JIAO, gastral cavity ruffian is not hungry, deficiency-cold in spleen and stomach, and vomiting is had loose bowels, pernicious vomiting, fetal irritability.
The bighead atractylodes rhizome: taste is sweet, bitter, warm in nature.Return spleen, stomach warp.There is tonifying spleen profit gas, eliminating dampness Li Shui, strengthening exterior and reducing sweat, the fortune spleen effect of moisturizing, cure mainly the caused ruffian of the dysfunction of the spleen in transport, QI failing to transform into body fluid and have one's mind filled with and rush down, phlegm and retained fluid oedema; The vexed lazyness speech of the deficiency of qi in middle-jiao, metrorrhagia and metrostaxis, proctoptosis with chronic dysentery; The cards such as solid in the playing of deficiency of the spleen causing weakness of QI, abnormal sweating spontaneous perspiration.
Fevervine: property is put down, sweet, the micro-hardship of taste.Expelling wind and activating blood flow, analgesic antidotal, promoting digestion, dehumidifying detumescence.Treatment of rheumatalgia pain, diarrhoea dysentery, dirty abdomen pain, deficiency of vital energy edema, dizzy food is few, hepatosplenomegaly, scrofula, acute appendicitis, nameless sores or boils, traumatic injury.
The root of large-flowered skullcap: property is bitter, cold.Return lung, courage, spleen, large intestine, small intestinl channel.Can heat-clearing and damp-drying drug, purging intense heat and detonicating, hemostasis, antiabortive, hypotensive.For damp-warm syndrome, heat temperature evil of vomitting uncomfortable in chest, damp and hot ruffian is full, and rush down dysentery, jaundice, cough with lung heat, high hot polydipsia, blood-head tells nosebleed, carbuncle sore tumefacting virus, fetal irritability.
Honeysuckle: cold in nature, taste is sweet.Return lung, the heart, stomach warp.There is effect that clearing heat and detoxicating, anti-inflammatory, qi-restoratives treat wind, cure mainly disease under turgor, warm disease heating, the diseases such as hot malicious large carbuncle and tumour.The illnesss such as it is dizzy for giddy, dry is done yearningly, hidrosis is unhappy, enteritis, bacillary dysentery, measles, pneumonia, encephalitis, epidemic meningitis, acute mastitis, septicemia, appendicitis, skin infection, ulcer furunculosis, erysipelas, mumps, suppurative tonsillitis all have certain curative effect.
Mountain on the other way round disappears: bitter but sweet flavor is puckery, and slightly warm in nature is nontoxic.Return liver, kidney two warp.Nourishing liver and kidney, strengthening body, nourishes blood and enriches blood, black of crow palpus, and convergence vital essence, regenerating tissue to heal wond, relaxes bowel.Control prolonged illness weakness, chronic wandering arthritis, soreness and weakness of waist and knees, anaemia, enterorrhagia, poliosis, neurasthenia, deficiency of Yin chronic malaria, ulcer does not close up for a long time, old people constipation.
Asafoetide: bitter, pungent, warm in nature.Return kidney, stomach warp.Have and disappear long-pending, loose ruffian, effect of desinsection, stagnates for meat, hemostasis abdominal mass, mass in abdomen, the cards such as abdominal pain due to enterositosis.
Raddle: bitter sweet is flat.Return liver, stomach, heart born of the same parents warp.Ping Gan town is inverse, cooling blood and hemostasis.Controlling gas vomits inverse, dysphagia and regurgitation, asthma, and frightened epilepsy, spit blood, nosebleed epistaxis, intestines wind, hemorrhoid complicated by anal fistula, under uterine bleeding band.
Caulis bambusae in taenian: cold nature, taste is sweet.Attach to the lung and stomach meridians.Function clearing heat and eliminating phlegm, relieves restlessness and prevents vomiting.Phlegm, dysphoria with smothery sensation vomiting, palpitation with fear insomnia, apoplexy phlegm fan, aphasia with stiff tongue, gastropyretic vomiting, pernicious vomiting, fetal irritability is held under the arm for phlegm-heat cough, courage fire.
Yncaria stem with hooks: sweet, bitter, be slightly cold.Return Liver Channel, the heart channel of Hang-Shaoyin.The flat liver of function heat-clearing, relieving convulsion and spasm.Cure mainly child convulsion, the morbid night crying of babies, heat contains dynamic wind, eclampsia, dizziness due to hyperactivity of liver-YANG, irascibility distending pain in the head.
Rhizoma Gastrodiae: Gan Ping.Return Liver Channel.Embellish but not dry, master enters Liver Channel, is longer than suppressing hyperactive liver for calming endogenous wind, the disease of all liver wind agitations, vertigo, no matter actual situation, is key medicine.
Rhizoma arisaematis: bitter, pungent, temperature.Return lung, liver, the spleen channel.Eliminating dampness and eliminating phlegm, expelling wind and relieving convulsion, mass dissipating and swelling eliminating.Cough for stupid productive cough, wind disease is dizzy, and apoplexy phlegm is stopped up, facial paralysis, hemiplegia, epilepsy, infantile convulsion, lockjaw; Swell for carbuncle outward, snake bite and insect sting.
Borneol: arduous, cool.The thoughts of returning home, lung channel.Logical all keys, loose stagnated fire, goes screen improving eyesight, swelling and pain relieving.Control middle air port to keep silent, pyreticosis coma, frightened epilepsy phlegm fan, deafness with qi stagnation, larynx numbness, aphtha, tympanitis, carbuncle swells, and hemorrhoid, order is screen film also, enterobiasis.
Bluish dogbane: sweetness and bitterness is cool.Control heart disease, hypertension, neurasthenia, hepatitis abdominal distension, ephritis edema.
Selfheal: bitter, pungent, cold in nature.Return liver, gallbladder channel." have and relieve inflammation or internal heat, improving eyesight, dissipating bind, effect of detumescence, cures mainly red eye, swell pain, and order pearl nyctalgia, has a headache dizzy, scrofula, and goiter and tumor, swells and ache; Thyroid Gland Swell, scrofula, the proliferation of mammary gland, the cards such as hypertension, hyperglycaemia, high fat of blood and high blood are sticky.
Akebi: bitter, cold in nature.Thoughts of returning home warp, small intestinl channel, urinary bladder channel.Function inducing diuresis for treating strangurtia, clear away heart-fire relieving restlessness, lactogenesis of stimulating the menstrual flow.For stranguria, oedema, vexed urine is red, few through closing breast, damp-heat arthralgia pain.This product energy inducing diuresis for removing edema, lower dampness removing heat, makes that damp and hot heresy is descending discharges from urine.
Umbellate pore furgus: taste is sweet, light, flat.The thoughts of returning home, spleen, stomach, lung, kidney, warp.Control difficult urination, oedema, to have loose bowels, stranguria with turbid discharge, under band.
Rhizoma alismatis: taste is sweet, light, cold in nature.Return kidney, urinary bladder channel.There is clearing damp and promoting diuresis, the lung that clears away heart-fire, rush down effect of kidney fire.Be mainly used in insufficiency of the spleen retention of water-damp, the wet anasarca of spreading unchecked of water; Heresy that water drink phlegm is wet is tired to be hindered, and what cause that lucid yang failing to raise voiced sound do not fall is dizzy; The difficult urination of damp invasion of lower energizer, red short puckery pain, and the card such as jaundice with damp-heat pathogen.
Radix Glycyrrhizae: nature and flavor are sweet, flat.Return spleen, stomach, lung channel.Can beneficial gas bowl spares, relieving spasm to stop pain, moistens the lung and relieve the cough, purging intense heat and detonicating, coordinating the drug actions of a prescription.Main burnout food is few, flesh thin Huang, palpitation, stomachache loose stool, and the anxious pain of four limbs contraction, hysteria, cough and asthma, abscess of throat, carbuncle sore swells and ache, infant fetal toxin, and medicine, food poisoning.
Herba Andrographitis: have clearing heat and detoxicating, anti-inflammatory, swelling and pain relieving effect.Cure mainly bacillary dysentery, urinary tract infections, acute tonsillitis, enteritis, sphagitis, pneumonia and influenza etc., external application can treat sore furuncle poison, trauma infection contamination etc.
Rhizome of cyrtomium: nature and flavor are bitter, are slightly cold.Return liver, the spleen channel.Have clearing heat and detoxicating, cooling blood and hemostasis, effect of desinsection.Anemopyretic cold can be cured mainly, febrile virulent maculae; Blood-head is hemorrhage; Worm disease; This product also can be used for treatment burn and scald and married woman is with inferior disease.
Paris polyphylla: bitter, cold.Return Liver Channel.There is the merit of clearing heat and detoxicating, cool liver arresting convulsion, be applicable to multiple pathopyretic ulcer, abscess of throat, mumps, venomous snake bite, frightened epilepsy, unconsciousness due to high fever etc.
Oroxylum indicum: mildly bitter flavor, sweet, cold nature.Return lung, liver, stomach warp.Relieve sore throat moistening lung, soothing liver and harmonizing stomach, expelling pus and promoting granulation.Cure mainly pharyngalgia larynx numbness, hoarseness, cough, stomachache due to emotional depression and the hyperactive liver-qi attacking the stomach, sore is burst for a long time and is not held back, acute eczema.
Root of Loping Thistle: bitter is flat.Cool blood, Li Shui, dispels the wind, qi-restoratives.Control haematemesis, lower blood, oedema, weak, traumatic injury, large carbuncle is red and swollen, pruigo, mange.
Play both sides of the street: bitter, flat.Return liver, kidney channel.Dispelling, collateral-activating, Li Shui stimulates the menstrual flow.For joint pain, numbness contracture, oedema turgor, breast is few through closing.
Shoulder plate to return: acid; Bitter; Property is put down.Return lung; Small intestinl channel.Clearing heat and detoxicating; Inducing diuresis and reducing edema; Loose stasis of blood hemostasis.Main furunculosis carbuncle swells; Erysipelas; The paralysis cheek; Mastitis; Ting ear; Tonsillitis; Cold, fever; Cough with lung heat; Pertussis; Scrofula; Haemorrhoids; Lymphogranuloma inguinale bubo; Rush down dysentery; Jaundice; Tympanites; Oedema; Stranguria with turbid discharge; Under band; Malaria; Wind fire cute conjunctivitis; Treating swelling and pain by traumatic injury; Spit blood; Have blood in stool; Snake bite and insect sting.
In feed, the weight portion of each component is institute Chinese medicine additive 12-16 weight portion, trace element chelated dose of 2-6 weight portion, sugared brewer's yeast 0.2-0.7 weight portion, corn 46-67 weight portion, hay 41-65 weight portion, bacillus 0.4-0.9 weight portion, montmorillonite 3-5 weight portion.
Bacillus comprises one or both mixing in bacillus subtilis and bacillus licheniformis.
Trace element chelated dose comprises hemoglobin, cytochrome oxidase and vitamin B12.
In Chinese medicine additive, the weight portion of each bulk drug also can be: Divine Comedy 19-31 weight portion, rice bud 13-22 weight portion, fructus amomi 21-30 weight portion, bighead atractylodes rhizome 25-32 weight portion, fevervine 13-21 weight portion, root of large-flowered skullcap 22-33 weight portion, honeysuckle 30-38 weight portion, mountain on the other way round disappears 16-24 weight portion, asafoetide 12-22 weight portion, raddle 16-25 weight portion, caulis bambusae in taenian 18-27 weight portion, yncaria stem with hooks 9-18 weight portion, rhizoma Gastrodiae 23-33 weight portion, rhizoma arisaematis 3-7 weight portion, borneol 19-26 weight portion, bluish dogbane 22-33 weight portion, selfheal 11-20 weight portion, akebi 30-37 weight portion, umbellate pore furgus 20-28 weight portion, rhizoma alismatis 17-26 weight portion, Radix Glycyrrhizae 14-21 weight portion, Herba Andrographitis 23-32 weight portion, rhizome of cyrtomium 5-11 weight portion, Paris polyphylla 10-18 weight portion, Oroxylum indicum 14-25 weight portion, Root of Loping Thistle 27-37 weight portion, play both sides of the street 20-31 weight portion and shoulder plate 11-24 weight portion.
In Chinese medicine additive, the weight portion of each bulk drug can be again: Divine Comedy 21-28 weight portion, rice bud 14-21 weight portion, fructus amomi 23-28 weight portion, bighead atractylodes rhizome 26-31 weight portion, fevervine 15-20 weight portion, root of large-flowered skullcap 24-30 weight portion, honeysuckle 31-37 weight portion, mountain on the other way round disappears 17-22 weight portion, asafoetide 14-20 weight portion, raddle 18-23 weight portion, caulis bambusae in taenian 19-25 weight portion, yncaria stem with hooks 10-17 weight portion, rhizoma Gastrodiae 25-31 weight portion, rhizoma arisaematis 3-6 weight portion, borneol 19-24 weight portion, bluish dogbane 22-29 weight portion, selfheal 11-18 weight portion, akebi 32-37 weight portion, umbellate pore furgus 21-27 weight portion, rhizoma alismatis 17-23 weight portion, Radix Glycyrrhizae 14-18 weight portion, Herba Andrographitis 25-31 weight portion, rhizome of cyrtomium 5-9 weight portion, Paris polyphylla 10-16 weight portion, Oroxylum indicum 16-24 weight portion, Root of Loping Thistle 28-36 weight portion, play both sides of the street 21-28 weight portion and shoulder plate and return 13-21 weight portion.
Present invention also offers a kind of preparation method of the feed for preventing and treating bowel oedema disease, comprising the following steps:
The first step, corn, hay are dropped in mixer in proportion and mixes, adding water, controlling the content of moisture in mixture is 59%-82%, stir, after add brewer's yeast, bacillus in proportion, mixed material is added in horizental silo, by the material compacting mixed, cover tightly, cause internal batch anaerobic environment, at the temperature bottom fermentation 35-40 days of 19 DEG C-30 DEG C, rear acquisition fermented product, carries out drying by fermentation material, obtain the solid fermentation product of moisture below 7%, be ground into powder;
Second step, montmorillonite adopts micronizer to be ground into the ultra-micro powder of 16-31 μm;
3rd step, each bulk drug in Chinese medicine additive is mixed in proportion, adding relative to the determining alcohol of its quality 3 times is subsequently the ethanol of 73-86%, add hot reflux 2 hours, filter, by filtered fluid at-1.0 DEG C refrigerated overnight, again filter, decompression recycling ethanol, is ground into powder, obtains Chinese medicine additive powder;
4th step, mixes the Chinese medicine additive powder of the montmorillonite ultra-micro powder of the fermented product powder of first step acquisition, second step acquisition, the 3rd step acquisition and trace element chelated dose in proportion, namely obtains described feed.
A kind of Chinese medicine composition for preventing and treating bowel oedema disease, in Chinese medicine composition each bulk drug ratio of weight and number be: Divine Comedy 16-35 weight portion, rice bud 11-25 weight portion, fructus amomi 19-32 weight portion, bighead atractylodes rhizome 23-34 weight portion, fevervine 10-25 weight portion, root of large-flowered skullcap 20-36 weight portion, honeysuckle 28-40 weight portion, mountain on the other way round disappears 14-26 weight portion, asafoetide 10-24 weight portion, raddle 14-28 weight portion, caulis bambusae in taenian 15-30 weight portion, yncaria stem with hooks 7-21 weight portion, rhizoma Gastrodiae 21-35 weight portion, rhizoma arisaematis 3-8 weight portion, borneol 16-28 weight portion, bluish dogbane 20-35 weight portion, selfheal 9-23 weight portion, akebi 28-40 weight portion, umbellate pore furgus 18-30 weight portion, rhizoma alismatis 15-28 weight portion, Radix Glycyrrhizae 12-24 weight portion, Herba Andrographitis 21-34 weight portion, rhizome of cyrtomium 5-13 weight portion, Paris polyphylla 8-21 weight portion, Oroxylum indicum 12-28 weight portion, Root of Loping Thistle 25-39 weight portion, play both sides of the street 18-34 weight portion and shoulder plate and return 9-27 weight portion.
For preventing and treating a Chinese medicine composition for bowel oedema disease, the preparation method of Chinese traditional medicine composition composition powders comprises:
Step one, all bulk drugs are dropped in proportion in mixer stir, mixing, pulverize in rear feeding pulverizer, the Chinese medicine composition after pulverizing is loaded in multi-function extractor, add relative to its quality 5-7 times amount water, boil 2-4 hour, steam pressure is 0.6-1Mpa process, filter, obtain the first filtered fluid and filter residue;
Step 2, the filter residue of acquisition added again relative to its quality 5-7 times amount water, boil 2-4 hour, steam pressure is 0.6Mpa-1Mpa process, filter and obtain the second filtered fluid and filter residue;
Step 3, the first filtered fluid and the second filtered fluid merged, concentrated removing moisture, obtains and gets dry extract, and adopts super-fine powder mill to pulverize, is crushed to less than 30 μm, obtain Chinese medicine additive powder.
The toxicity test of embodiment 1 Chinese medicine composition of the present invention
Get Divine Comedy 23g, rice bud 17g, fructus amomi 25g, bighead atractylodes rhizome 27g, fevervine 16g, root of large-flowered skullcap 28g, honeysuckle 33g, mountain on the other way round disappear 19g, asafoetide 15g, raddle 23g, caulis bambusae in taenian 24g, yncaria stem with hooks 10g, rhizoma Gastrodiae 27g, rhizoma arisaematis 6g, borneol 20g, bluish dogbane 23g, selfheal 16g, akebi 34g, umbellate pore furgus 27g, rhizoma alismatis 20g, Radix Glycyrrhizae 16g, Herba Andrographitis 29g, rhizome of cyrtomium 8g, Paris polyphylla 11g, Oroxylum indicum 23g, Root of Loping Thistle 35g, play both sides of the street 27g and shoulder plate and return 20g; After mixing, pulverize, in the mixture after pulverizing, add the water of 1500g, decoct 2.5 hours, filter, the water adding 650g in filter residue decocts 1.5 hours again, filters, and by twice filtrate mixing, is evaporated to the decoction that crude drug concentration is 3g/ml.
Get ICR mouse, body weight, at 25-30 gram, by body weight random packet, often organizes 10, male and female half and half, oral administration solution administration, and dosage is only 6.0ml/.Continuous Observation 20 days after administration, all mouse of result are strong deposits, and its activity, diet, hair, excreta are no abnormal, have no toxic reaction.Irritation test is carried out to white mouse oral cavity and damaged skin, there are no irritative response and other bad reaction.
Toxicity test proves, the not toxic effect of this medicine and bad reaction, clinical practice is safe and reliable.
Embodiment 2 Chinese medicine composition 1 of the present invention and preparation method
Get Divine Comedy 25g, rice bud 15g, fructus amomi 28g, bighead atractylodes rhizome 30g, fevervine 19g, root of large-flowered skullcap 25g, honeysuckle 36g, mountain on the other way round disappear 21g, asafoetide 19g, raddle 18g, caulis bambusae in taenian 19g, yncaria stem with hooks 16g, rhizoma Gastrodiae 31g, rhizoma arisaematis 4, borneol 23g, bluish dogbane 28g, selfheal 12g, akebi 32g, umbellate pore furgus 22g, rhizoma alismatis 18g, Radix Glycyrrhizae 17g, Herba Andrographitis 26g, rhizome of cyrtomium 6g, Paris polyphylla 15g, Oroxylum indicum 17g, Root of Loping Thistle 30g, play both sides of the street 22g and shoulder plate and return 14g; Drop into stirring in mixer, mixing, pulverize in rear feeding pulverizer, the Chinese medicine composition after pulverizing loaded in multi-function extractor, add relative to its quality 5 times amount water, boil 2 hours, steam pressure is 0.7Mpa process, filter, obtain the first filtered fluid and filter residue; The filter residue of acquisition is added again relative to its quality 6 times amount water, boil 3 hours, steam pressure is 0.8Mpa process, filter and obtain the second filtered fluid and filter residue; First filtered fluid and the second filtered fluid are merged, concentrated removing moisture, obtains and gets dry extract, and adopts super-fine powder mill to pulverize, is crushed to less than 30 μm, obtain Chinese medicine additive powder.
Embodiment 3 Chinese medicine composition 2 of the present invention and preparation method
Get Divine Comedy 26g, rice bud 20g, fructus amomi 23g, bighead atractylodes rhizome 31g, fevervine 18g, root of large-flowered skullcap 29g, honeysuckle 31g, mountain on the other way round disappear 20g, asafoetide 16g, raddle 22g, caulis bambusae in taenian 25g, yncaria stem with hooks 15g, rhizoma Gastrodiae 30g, rhizoma arisaematis 5, borneol 19g, bluish dogbane 27g, selfheal 17g, akebi 36g, umbellate pore furgus 24g, rhizoma alismatis 22g, Radix Glycyrrhizae 18g, Herba Andrographitis 30g, rhizome of cyrtomium 5g, Paris polyphylla 13g, Oroxylum indicum 20g, Root of Loping Thistle 29g, play both sides of the street 24g and shoulder plate and return 16g; Drop into stirring in mixer, mixing, pulverize in rear feeding pulverizer, the Chinese medicine composition after pulverizing loaded in multi-function extractor, add relative to its quality 7 times amount water, boil 4 hours, steam pressure is 0.8Mpa process, filter, obtain the first filtered fluid and filter residue; The filter residue of acquisition is added again relative to its quality 5 times amount water, boil 2 hours, steam pressure is 0.9Mpa process, filter and obtain the second filtered fluid and filter residue; First filtered fluid and the second filtered fluid are merged, concentrated removing moisture, obtains and gets dry extract, and adopts super-fine powder mill to pulverize, is crushed to less than 30 μm, obtain Chinese medicine additive powder.
Embodiment 4 Chinese medicine composition 3 of the present invention and preparation method
Get Divine Comedy 21g, rice bud 14g, fructus amomi 27g, bighead atractylodes rhizome 26g, fevervine 15g, root of large-flowered skullcap 30g, honeysuckle 35g, mountain on the other way round disappear 22g, asafoetide 18g, raddle 21g, caulis bambusae in taenian 20g, yncaria stem with hooks 13g, rhizoma Gastrodiae 25g, rhizoma arisaematis 3, borneol 22g, bluish dogbane 24g, selfheal 18g, akebi 33g, umbellate pore furgus 26g, rhizoma alismatis 23g, Radix Glycyrrhizae 15g, Herba Andrographitis 31g, rhizome of cyrtomium 7g, Paris polyphylla 14g, Oroxylum indicum 24g, Root of Loping Thistle 28g, play both sides of the street 26g and shoulder plate and return 18g; Drop into stirring in mixer, mixing, pulverize in rear feeding pulverizer, the Chinese medicine composition after pulverizing loaded in multi-function extractor, add relative to its quality 5 times amount water, boil 2 hours, steam pressure is 0.9Mpa process, filter, obtain the first filtered fluid and filter residue; The filter residue of acquisition is added again relative to its quality 7 times amount water, boil 4 hours, steam pressure is 0.6Mpa process, filter and obtain the second filtered fluid and filter residue; First filtered fluid and the second filtered fluid are merged, concentrated removing moisture, obtains and gets dry extract, and adopts super-fine powder mill to pulverize, is crushed to less than 30 μm, obtain Chinese medicine additive powder.
Embodiment 5 feed 1 of the present invention and preparation method
A kind of feed, comprise Chinese medicine additive, montmorillonite, brewer's yeast, trace element chelated dose, corn, hay, bacillus; In feed, the weight portion of each component is: Chinese medicine additive 13 weight portion, trace element chelated dose of 3 weight portion, sugared brewer's yeast 0.7 weight portion, corn 60 weight portion, hay 45 weight portion, bacillus 0.8 weight portion, montmorillonite 3 weight portion.
Bacillus is bacillus subtilis.
Trace element chelated dose is hemoglobin, cytochrome oxidase and vitamin B12.
The preparation method of feed, comprises the following steps:
The first step, drops into corn, hay in mixer in proportion and mixes, and adding water, controlling the content of moisture in mixture is 80%, stir, after add brewer's yeast, bacillus in proportion, mixed material is added in horizental silo, by the material compacting mixed, covers tightly, cause internal batch anaerobic environment, at the temperature bottom fermentation 35 days of 30 DEG C, rear acquisition fermented product, carries out drying by fermentation material, obtain moisture at the solid fermentation product of 6%, be ground into powder;
Second step, described montmorillonite adopts micronizer to be ground into the ultra-micro powder of 16-31 μm;
3rd step, each bulk drug in described Chinese medicine additive is mixed in proportion, adding relative to the determining alcohol of its quality 3 times is subsequently the ethanol of 75%, add hot reflux 2 hours, filter, by filtered fluid at-1.0 DEG C refrigerated overnight, again filter, decompression recycling ethanol, is ground into powder, obtains Chinese medicine additive powder;
4th step, mixes the Chinese medicine additive powder of the montmorillonite ultra-micro powder of the fermented product powder of first step acquisition, second step acquisition, the 3rd step acquisition and trace element chelated dose in proportion, namely obtains described feed.
Embodiment 6 feed 2 of the present invention and preparation method
A kind of feed, comprise Chinese medicine additive, montmorillonite, brewer's yeast, trace element chelated dose, corn, hay, bacillus; In feed, the weight portion of each component is: Chinese medicine additive 16 weight portion, trace element chelated dose of 3 weight portion, sugared brewer's yeast 0.5 weight portion, corn 50 weight portion, hay 55 weight portion, bacillus 0.6 weight portion, montmorillonite 4 weight portion.
Bacillus is two kinds of mixing in bacillus subtilis and bacillus licheniformis.
Trace element chelated dose is the mixture of hemoglobin, cytochrome oxidase and vitamin B12.
The preparation method of feed, comprises the following steps:
The first step, drops into corn, hay in mixer in proportion and mixes, and adding water, controlling the content of moisture in mixture is 62%, stir, after add brewer's yeast, bacillus in proportion, mixed material is added in horizental silo, by the material compacting mixed, covers tightly, cause internal batch anaerobic environment, at the temperature bottom fermentation 35 days of 25 DEG C, rear acquisition fermented product, carries out drying by fermentation material, obtain moisture at the solid fermentation product of 5%, be ground into powder;
Second step, montmorillonite adopts micronizer to be ground into the ultra-micro powder of 16-31 μm;
3rd step, each bulk drug in described Chinese medicine additive is mixed in proportion, adding relative to the determining alcohol of its quality 3 times is subsequently the ethanol of 80%, add hot reflux 2 hours, filter, by filtered fluid at-1.0 DEG C refrigerated overnight, again filter, decompression recycling ethanol, is ground into powder, obtains Chinese medicine additive powder;
4th step, mixes the Chinese medicine additive powder of the montmorillonite ultra-micro powder of the fermented product powder of first step acquisition, second step acquisition, the 3rd step acquisition and trace element chelated dose in proportion, namely obtains described feed.
Embodiment 7 clinical testing
(1) for examination animal
Choose the hybridization piggy of 120 natural occurrences in Changsha diversified farm pig farm as treatment contrast test object; Separately from Changsha diversified farm pig farm, random selecting 80 health hybridizes piggy as prevention contrast test object.
(2) bacterial strain extracts and cultivates:
Asepticly get pork liver of dying of illness, lymph node, lung, small intestine leading portion content carry out contact, gram stain microscopy, visible Gram-negative dialister bacterium respectively.Lymph node, small intestine leading portion content are inoculated in cultured solution of broth, for subsequent use.Cultured solution of broth is evenly muddy, has canescence emplastic to precipitate.Visible grey, slightly transparent, the irregular bacterium colony in circular protrusions, edge on nutrient agar.Culture respectively smear, gram stain microscopy, single or arrange in pairs, the Gram-negative dialister bacterium of the blunt circle in two ends as seen.
(3) contrast experiment is prevented:
80 of random choose health pig are divided at random 2 groups (control group 1 and embodiment groups), wherein, control group 1 uses traditional pig feed to feed pig, embodiment group uses the feed 1 in embodiment 5 to feed pig, feed after 20 days, the 5 times dilutions of artificial challenge with culture for subsequent use are carried out to control group 1 and embodiment group, lumbar injection 0.2mL/kg, observed and recorded respectively organizes the incidence of disease and the death rate of pig, and result is as shown in table 1.
The table 1 preventive effect table of comparisons
Data from table 1: the feed that the present invention contains Chinese medicine composition has obvious preventive effect to bowel oedema disease.
(4) contrast test is treated:
Curative effect determinate standard
Recovery from illness: after medication, nervous symptoms and the position such as face, eyelid oedema disappear, and spirit, appetite recover normal, do not recur in first quarter moon.
Take a turn for the better: after medication, symptom alleviates, spirit, appetite take a turn for the better.
Invalid: after medication, maintain former symptom or increase the weight of.
Efficient is cure rate and improvement rate sum.
Be divided at random by 120 of random selecting sick pigs 3 groups (treatment by Chinese herbs group, western medicine group, blank groups), treat with different medicine, wherein, treatment by Chinese herbs group selects the Chinese medicine composition 3 of embodiment 4, dose be every every day 0.8g/kg, treat 5 days; Western medicine group selects enrofloxacin injection 0.2ml/kg to carry out neck injection, treats 5 days; Blank group does not feed any medicine.Observed and recorded respectively organizes cure rate and the death rate of pig, and result is as shown in table 2.
The table 2 result for the treatment of table of comparisons
Data from table 2: Chinese medicine composition of the present invention is obviously better than western medicine group to the result for the treatment of of bowel oedema disease, reduce the death rate, improve cure rate.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (8)
1. for preventing and treating a feed for bowel oedema disease, it is characterized in that, comprising Chinese medicine additive, montmorillonite, brewer's yeast, trace element chelated dose, corn, hay, bacillus, in described Chinese medicine additive, the ratio of weight and number of each bulk drug is: Divine Comedy 16-35 weight portion, rice bud 11-25 weight portion, fructus amomi 19-32 weight portion, bighead atractylodes rhizome 23-34 weight portion, fevervine 10-25 weight portion, root of large-flowered skullcap 20-36 weight portion, honeysuckle 28-40 weight portion, mountain on the other way round disappears 14-26 weight portion, asafoetide 10-24 weight portion, raddle 14-28 weight portion, caulis bambusae in taenian 15-30 weight portion, yncaria stem with hooks 7-21 weight portion, rhizoma Gastrodiae 21-35 weight portion, rhizoma arisaematis 3-8 weight portion, borneol 16-28 weight portion, bluish dogbane 20-35 weight portion, selfheal 9-23 weight portion, akebi 28-40 weight portion, umbellate pore furgus 18-30 weight portion, rhizoma alismatis 15-28 weight portion, Radix Glycyrrhizae 12-24 weight portion, Herba Andrographitis 21-34 weight portion, rhizome of cyrtomium 5-13 weight portion, Paris polyphylla 8-21 weight portion, Oroxylum indicum 12-28 weight portion, Root of Loping Thistle 25-39 weight portion, play both sides of the street 18-34 weight portion and shoulder plate and return 9-27 weight portion.
2. the feed for preventing and treating bowel oedema disease according to claim 1, it is characterized in that, in described feed, the weight portion of each component is: described Chinese medicine additive 12-16 weight portion, trace element chelated dose of 2-6 weight portion, brewer's yeast 0.2-0.7 weight portion, corn 46-67 weight portion, hay 41-65 weight portion, bacillus 0.4-0.9 weight portion, montmorillonite 3-5 weight portion.
3. the feed for preventing and treating bowel oedema disease according to claim 1, is characterized in that, described bacillus comprises one or both mixing in bacillus subtilis and bacillus licheniformis.
4. the feed for preventing and treating bowel oedema disease according to claim 1, is characterized in that, described trace element chelated dose comprises hemoglobin, cytochrome oxidase and Cobastab
12.
5. according to the arbitrary described feed for preventing and treating bowel oedema disease of claim 1-4, it is characterized in that, in described Chinese medicine additive, the weight portion of each bulk drug is: Divine Comedy 19-31 weight portion, rice bud 13-22 weight portion, fructus amomi 21-30 weight portion, bighead atractylodes rhizome 25-32 weight portion, fevervine 13-21 weight portion, root of large-flowered skullcap 22-33 weight portion, honeysuckle 30-38 weight portion, mountain on the other way round disappears 16-24 weight portion, asafoetide 12-22 weight portion, raddle 16-25 weight portion, caulis bambusae in taenian 18-27 weight portion, yncaria stem with hooks 9-18 weight portion, rhizoma Gastrodiae 23-33 weight portion, rhizoma arisaematis 3-7 weight portion, borneol 19-26 weight portion, bluish dogbane 22-33 weight portion, selfheal 11-20 weight portion, akebi 30-37 weight portion, umbellate pore furgus 20-28 weight portion, rhizoma alismatis 17-26 weight portion, Radix Glycyrrhizae 14-21 weight portion, Herba Andrographitis 23-32 weight portion, rhizome of cyrtomium 5-11 weight portion, Paris polyphylla 10-18 weight portion, Oroxylum indicum 14-25 weight portion, Root of Loping Thistle 27-37 weight portion, play both sides of the street 20-31 weight portion and shoulder plate and return 11-24 weight portion.
6. according to the arbitrary described feed for preventing and treating bowel oedema disease of claim 1-4, it is characterized in that, in described Chinese medicine additive, the weight portion of each bulk drug is: Divine Comedy 21-28 weight portion, rice bud 14-21 weight portion, fructus amomi 23-28 weight portion, bighead atractylodes rhizome 26-31 weight portion, fevervine 15-20 weight portion, root of large-flowered skullcap 24-30 weight portion, honeysuckle 31-37 weight portion, mountain on the other way round disappears 17-22 weight portion, asafoetide 14-20 weight portion, raddle 18-23 weight portion, caulis bambusae in taenian 19-25 weight portion, yncaria stem with hooks 10-17 weight portion, rhizoma Gastrodiae 25-31 weight portion, rhizoma arisaematis 3-6 weight portion, borneol 19-24 weight portion, bluish dogbane 22-29 weight portion, selfheal 11-18 weight portion, akebi 32-37 weight portion, umbellate pore furgus 21-27 weight portion, rhizoma alismatis 17-23 weight portion, Radix Glycyrrhizae 14-18 weight portion, Herba Andrographitis 25-31 weight portion, rhizome of cyrtomium 5-9 weight portion, Paris polyphylla 10-16 weight portion, Oroxylum indicum 16-24 weight portion, Root of Loping Thistle 28-36 weight portion, play both sides of the street 21-28 weight portion and shoulder plate and return 13-21 weight portion.
7., according to the preparation method of the arbitrary described feed for preventing and treating bowel oedema disease of claim 1-6, comprise the following steps:
The first step, corn, hay are dropped in mixer in proportion and mixes, adding water, controlling the content of moisture in mixture is 59%-82%, stir, after add brewer's yeast, bacillus in proportion, mixed material is added in horizental silo, by the material compacting mixed, cover tightly, cause internal batch anaerobic environment, fermented product is obtained after 35-40 days at the temperature bottom fermentation of 19 DEG C-30 DEG C, fermentation material is carried out drying, obtains the solid fermentation product of moisture below 7%, be ground into powder;
Second step, described montmorillonite adopts micronizer to be ground into the ultra-micro powder of 16-31 μm;
3rd step, each bulk drug in described Chinese medicine additive is mixed in proportion, adding relative to the determining alcohol of its quality 3 times is subsequently the ethanol of 73-86%, add hot reflux 2 hours, filter, by filtered fluid at-1.0 DEG C refrigerated overnight, again filter, decompression recycling ethanol, is ground into powder, obtains Chinese medicine additive powder;
4th step, mixes the Chinese medicine additive powder of the montmorillonite ultra-micro powder of the fermented product powder of first step acquisition, second step acquisition, the 3rd step acquisition and trace element chelated dose in proportion, namely obtains described feed.
8. one kind for preventing and treating the Chinese medicine composition of bowel oedema disease, it is characterized in that, in described Chinese medicine composition, the ratio of weight and number of each bulk drug is: Divine Comedy 16-35 weight portion, rice bud 11-25 weight portion, fructus amomi 19-32 weight portion, bighead atractylodes rhizome 23-34 weight portion, fevervine 10-25 weight portion, root of large-flowered skullcap 20-36 weight portion, honeysuckle 28-40 weight portion, mountain on the other way round disappears 14-26 weight portion, asafoetide 10-24 weight portion, raddle 14-28 weight portion, caulis bambusae in taenian 15-30 weight portion, yncaria stem with hooks 7-21 weight portion, rhizoma Gastrodiae 21-35 weight portion, rhizoma arisaematis 3-8 weight portion, borneol 16-28 weight portion, bluish dogbane 20-35 weight portion, selfheal 9-23 weight portion, akebi 28-40 weight portion, umbellate pore furgus 18-30 weight portion, rhizoma alismatis 15-28 weight portion, Radix Glycyrrhizae 12-24 weight portion, Herba Andrographitis 21-34 weight portion, rhizome of cyrtomium 5-13 weight portion, Paris polyphylla 8-21 weight portion, Oroxylum indicum 12-28 weight portion, Root of Loping Thistle 25-39 weight portion, play both sides of the street 18-34 weight portion and shoulder plate and return 9-27 weight portion.
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| CN105341410A (en) * | 2015-11-07 | 2016-02-24 | 黑龙江省农业科学院畜牧研究所 | Feed additive for preventing and curing pig rheumatism as well as preparation method and application thereof |
| CN105285417A (en) * | 2015-12-04 | 2016-02-03 | 山东新希望六和集团有限公司 | Formula feed for piglets and preparation method thereof |
| CN105456592A (en) * | 2015-12-31 | 2016-04-06 | 张明 | Traditional Chinese medicine composition for treating swine malignant edema |
| CN105816612A (en) * | 2016-04-27 | 2016-08-03 | 吴定文 | Decoction for relieving prenatal excessive swelling of ewes and processing method of decoction |
| CN106071229A (en) * | 2016-06-21 | 2016-11-09 | 山东新希望六和集团有限公司 | A kind of winter raises pigs and uses feed additive |
| CN106721325A (en) * | 2017-02-09 | 2017-05-31 | 安徽菲扬农业科技有限公司 | A kind of feed for preventing and treating bowel oedema disease |
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| CN101342276A (en) * | 2008-07-23 | 2009-01-14 | 孙庆敏 | Chinese medicinal herb for preventing and treating acute hydropsy of ablactated pigling and preparation method thereof |
| CN101554460A (en) * | 2009-05-19 | 2009-10-14 | 钱峰 | Edible/medicina traditional Chinese medicine combination for curing porcine diarrhea |
| CN102293871A (en) * | 2011-08-22 | 2011-12-28 | 格特生物制药（天津）有限公司 | Traditional Chinese medicinal composition for treating edema disease of piglets |
| CN102524584A (en) * | 2012-01-20 | 2012-07-04 | 漳州双胞胎饲料有限公司 | Composite pig feed additive for effectively preventing edema of pigs |
| CN102784306A (en) * | 2012-08-31 | 2012-11-21 | 山东新希望六和集团有限公司 | Traditional Chinese medicine composition and feed for treating piglet edema disease and preparation methods of traditional Chinese medicine composition and feed |
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2014
- 2014-05-09 CN CN201410193519.6A patent/CN103931953B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101342276A (en) * | 2008-07-23 | 2009-01-14 | 孙庆敏 | Chinese medicinal herb for preventing and treating acute hydropsy of ablactated pigling and preparation method thereof |
| CN101554460A (en) * | 2009-05-19 | 2009-10-14 | 钱峰 | Edible/medicina traditional Chinese medicine combination for curing porcine diarrhea |
| CN102293871A (en) * | 2011-08-22 | 2011-12-28 | 格特生物制药（天津）有限公司 | Traditional Chinese medicinal composition for treating edema disease of piglets |
| CN102524584A (en) * | 2012-01-20 | 2012-07-04 | 漳州双胞胎饲料有限公司 | Composite pig feed additive for effectively preventing edema of pigs |
| CN102784306A (en) * | 2012-08-31 | 2012-11-21 | 山东新希望六和集团有限公司 | Traditional Chinese medicine composition and feed for treating piglet edema disease and preparation methods of traditional Chinese medicine composition and feed |
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