CN103908634A - Traditional Chinese medicine for treating senile dementia and preparation method thereof - Google Patents
Traditional Chinese medicine for treating senile dementia and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine for treating senile dementia, which is prepared from the following medicinal materials in parts by weight: 10g of tuber pinellia, 8g of radix astragali, 12g of hemlock parsley, 10g of arisaema cum bile, 9g of radix curcumae, 9g of costus root, 10g of Japanese sweetflag, 10g of rhizoma cyperi, 12g of tuckahoe, 6g of immature bitter orange, 5g of crystobalite and 4g of Mucuna macrocarpa Wallich. The preparation method comprises the following steps: weighing the medicinal materials, putting into a container, adding 8 times of water, decocting for 1.5 hours, and filtering; adding 6 times of water into the filter residue, decocting for 1 hour, and filtering; and merging the filtrates, concentrating, drying and encapsulating. The clinical experiment proves that the traditional Chinese medicine can achieve the obvious effect of treating senile dementia by selecting the appropriate medicinal materials and proportioning thereof, and has the advantages of high safety and no toxic or side effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine that is used for the treatment of alzheimer disease and preparation method thereof.
Background technology
Alzheimer disease, claims again senile psychosis, is that a kind of brain carries out sexual involution disease.Primary disease is taking cerebral atrophy and degeneration as main, and intelligence is suffered destruction in various degree, clinical taking dementia as main manifestations.Primary disease age of onset is many, and after 60 years old, 70～80 years old more common above, and women is high compared with male's sickness rate, approximately 1.5: 2.1.It is reported, the sickness rate of developed country's over-65s alzheimer disease is 10%, 80 years old above can be up to 20%.Along with China's growth in the living standard, the prolongation of people's average life, primary disease sickness rate constantly increases, and becomes one of important topic in presbyatrics.Primary disease onset is slow, is difficult for causing that other people note.Early symptom is personality changes, and it is subjective, wilful that patient becomes, obstinate circuitous holding, selfish narrow, do not like the contacts with people, household is lacked to emotion, emotional lability, irritability, sometimes noisy, curse and beat without reason household, lack shame and moral sense, do not note health, even can't take care of oneself, usually collect the refuse such as paper scrap, cloth and collected.To the judgment generation obstacle of things, patient is often suspicious, occur being murdered, by steal, delusion of poverty, when aggravation, show rudimentary purpose enhancing, nude in the presence of all,, even there is infringement in hypersexuality.Treatment for alzheimer disease still lacks the effective medicine of generally recognized as safe at present.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine that is used for the treatment of alzheimer disease and preparation method thereof, by selecting suitable medical material and proportioning thereof, reach to contribute to the remarkable efficacy of patients with Alzheimer disease rehabilitation, and safe without toxic side effect.
In order to achieve the above object, the present invention is by the following technical solutions: a kind of Chinese medicine that is used for the treatment of alzheimer disease, is prepared from by the medical material of following weight proportion: 8～10 grams of the Rhizoma Pinelliaes, 8～10 grams of the Radixs Astragali, 10～12 grams of Rhizoma Chuanxiongs, 8～10 grams of Arisaema Cum Bile, 7～9 grams of Radix Curcumaes, 7～9 grams of Radix Aucklandiae (Radix Vladimiriae), 8～10 grams of Rhizoma Acori Graminei, 8～10 grams of Rhizoma Cyperis, 10～12 grams, Poria, 5～6 grams of Fructus Aurantii Immaturuss, 0～5 gram of Quartz Album, 0～4 gram of Caulis seu Radix Schisandrae Henryi.
As preferably, be prepared from by the medical material of following weight proportion: 10 grams of the Rhizoma Pinelliaes, 8 grams of the Radixs Astragali, 12 grams of Rhizoma Chuanxiongs, 10 grams of Arisaema Cum Bile, 9 grams of Radix Curcumaes, 9 grams of Radix Aucklandiae (Radix Vladimiriae), 10 grams of Rhizoma Acori Graminei, 10 grams of Rhizoma Cyperis, 12 grams, Poria, 6 grams of Fructus Aurantii Immaturuss.
As preferably, be prepared from by the medical material of following weight proportion: 10 grams of the Rhizoma Pinelliaes, 8 grams of the Radixs Astragali, 12 grams of Rhizoma Chuanxiongs, 10 grams of Arisaema Cum Bile, 9 grams of Radix Curcumaes, 9 grams of Radix Aucklandiae (Radix Vladimiriae), 10 grams of Rhizoma Acori Graminei, 10 grams of Rhizoma Cyperis, 12 grams, Poria, 6 grams of Fructus Aurantii Immaturuss, 4 grams of Caulis seu Radix Schisandrae Henryi.
As preferably, be prepared from by the medical material of following weight proportion: 10 grams of the Rhizoma Pinelliaes, 8 grams of the Radixs Astragali, 12 grams of Rhizoma Chuanxiongs, 10 grams of Arisaema Cum Bile, 9 grams of Radix Curcumaes, 9 grams of Radix Aucklandiae (Radix Vladimiriae), 10 grams of Rhizoma Acori Graminei, 10 grams of Rhizoma Cyperis, 12 grams, Poria, 6 grams of Fructus Aurantii Immaturuss, 5 grams of Quartz Albums.
As preferably, be prepared from by the medical material of following weight proportion: 10 grams of the Rhizoma Pinelliaes, 8 grams of the Radixs Astragali, 12 grams of Rhizoma Chuanxiongs, 10 grams of Arisaema Cum Bile, 9 grams of Radix Curcumaes, 9 grams of Radix Aucklandiae (Radix Vladimiriae), 10 grams of Rhizoma Acori Graminei, 10 grams of Rhizoma Cyperis, 12 grams, Poria, 6 grams of Fructus Aurantii Immaturuss, 5 grams of Quartz Albums, 4 grams of Caulis seu Radix Schisandrae Henryi.
A kind of preparation method of the Chinese medicine that is used for the treatment of alzheimer disease, comprise the steps: to take the Rhizoma Pinelliae, the Radix Astragali, Rhizoma Chuanxiong, Arisaema Cum Bile, Radix Curcumae, Radix Aucklandiae (Radix Vladimiriae), Rhizoma Acori Graminei, Rhizoma Cyperi, Poria, Fructus Aurantii Immaturus, Quartz Album, Caulis seu Radix Schisandrae Henryi, insert in container, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell.
As preferably, comprise the steps: to take the Rhizoma Pinelliae, the Radix Astragali, Rhizoma Chuanxiong, Arisaema Cum Bile, Radix Curcumae, Radix Aucklandiae (Radix Vladimiriae), Rhizoma Acori Graminei, Rhizoma Cyperi, Poria, Fructus Aurantii Immaturus, Quartz Album, Caulis seu Radix Schisandrae Henryi, insert in container, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, dry, then add appropriate dextrin and correctives, granulate according to this area common process.
As preferably, comprise the steps: to take the Rhizoma Pinelliae, the Radix Astragali, Rhizoma Chuanxiong, Arisaema Cum Bile, Radix Curcumae, Radix Aucklandiae (Radix Vladimiriae), Rhizoma Acori Graminei, Rhizoma Cyperi, Poria, Fructus Aurantii Immaturus, Quartz Album, Caulis seu Radix Schisandrae Henryi, insert in container, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, concentrated, dry, pulverize.
The pharmacology analysis of the each Chinese medicinal ingredients of the present invention is as follows:
The Rhizoma Pinelliae [source] this product is the dry tuber of the aroid Rhizoma Pinelliae.[nature and flavor] are pungent, temperature; Poisonous.[return through] returns spleen, stomach, lung meridian.[function cures mainly] drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.For abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm headache, vomiting regurgitation, breast gastral cavity painful abdominal mass is vexed, globus hystericus.
The dry root of the Radix Astragali [source] leguminous plant Radix Astagali.[nature and flavor] are sweet, temperature.[return through] returns lung, spleen channel.[function cures mainly] invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.
The dry rhizome of Rhizoma Chuanxiong [source] samphire Rhizoma Chuanxiong.[nature and flavor] are pungent, temperature.[return through] returns liver, gallbladder, pericardium channel.[function cures mainly] blood-activating and qi-promoting, wind-expelling pain-stopping.
The processed goods that Arisaema Cum Bile [source] is made through fermentation for Rhizoma Arisaematis (processed) fine powder and cattle, sheep or Fel Sus domestica mixing or Arisaema Cum Bile fine powder and cattle, sheep or Fel Sus domestica.[nature and flavor] bitter in the mouth, cool in nature.[function cures mainly] clearing away fire and eliminating phlegm, relieving convulsion fixed chronic.Control middle wind-phlegm fan, infantile convulsion epilepsy, phlegm-fire is breathed heavily and is coughed, phlegm-accumulating vertigo.
Radix Curcumae [nature and flavor] is pungent, bitter, cold.[return through] returns liver, the heart, lung meridian.[function cures mainly] regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice.For amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, calentura coma, epilepsy is gone mad, jaundice dark coloured urine.
Radix Aucklandiae (Radix Vladimiriae) [nature and flavor] is pungent, bitter, temperature.[return through] returns spleen, stomach, large intestine, three warmers, gallbladder meridian.[function cures mainly] promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion.For breast gastral cavity distending pain, heavy after dysentery, food stagnation does not disappear, anorexia.Stomachache is used for having loose bowels.
The rhizome of Rhizoma Acori Graminei [source] acorus gramineus araceae plant.[function cures mainly] removing dampness appetizing, the eliminating phlegm of having one's ideas straightened out, refreshment Fructus Alpiniae Oxyphyllae.Not hungry for gastral cavity painful abdominal mass, mouthful dysentery of keeping silent, coma epilepsy, forgetful deafness.Regulate the flow of vital energy, invigorate blood circulation, loose wind, dries.Control epilepsy, syncope due to accumulation of phlegm, calentura coma, forgetful, deafness with qi stagnation, ambition unhappiness, stomachache, stomachache, anemofrigid-damp arthralgia, swollen ulcer drug, traumatic injury.
Rhizoma Cyperi [source] this product is the dry rhizome of sedge dried tuber.[nature and flavor] pungent, micro-hardship, micro-sweet, flat.[return through] returns liver, spleen, tri-jiao channel.[function cures mainly] promoting QI circulation for relieving depression, menstruction regulating and pain relieving.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, colic of cold type stomachache, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.
Poria [nature and flavor] is sweet, light, flat.[return through] GUIXIN, lung, spleen, kidney channel.[function cures mainly] promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
The dry young fruit of Fructus Aurantii Immaturus [source] Fructus Citri sinensis.[function cures mainly] dispelling the stagnated QI removing food stagnancy, the loose painful abdominal mass of reducing phlegm.In stagnant, stop, feeling of fullness distending pain, heavy after dysentery, constipation, the stagnant vapour lock thoracic obstruction of expectorant, blocked-up chest etc.
The silicon dioxide Ore that Quartz Album [source] is a kind of bulk.[nature and flavor] are sweet, tepor.[function cures mainly] tranquillizing and allaying excitement, cough-relieving, sending down the abnormal ascending QI.Be used for the uneasiness of palpitating with fear, cough with dyspnea.
Caulis seu Radix Schisandrae Henryi [source] is rattan or the root of Magnoliacea plant schisandra henryi Clarke or schisandra chinensis.[nature and flavor] are sad, temperature.[function cures mainly] repercussive that nourishes blood, regulating QI to expel dampness.Control consumptive disease wound and spit blood, podomere ache, heart peratodynia, beriberi flaccidity syndrome and arthralgia syndrome, menoxenia, traumatic injury.
Below in conjunction with clinical experiment data declaration beneficial effect of the present invention:
Through clinical patient's 355 examples of accepting alzheimer disease for medical treatment, take the oral agents of making according to embodiment 1, two doses of every days, use continuously 30 days.Therapeutic evaluation: cure: transference cure; Effective: symptom alleviates, but do not disappear completely; Invalid: symptom does not disappear, without obviously changing.
Therapeutic outcome: cure and effective totally 326 examples, effective percentage, up to 91.8%, is followed up a case by regular visits to after March again, all without recurrence.
Detailed description of the invention
In order to understand better and to implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: 10 grams of the Rhizoma Pinelliaes, 8 grams of the Radixs Astragali, 12 grams of Rhizoma Chuanxiongs, 10 grams of Arisaema Cum Bile, 9 grams of Radix Curcumaes, 9 grams of Radix Aucklandiae (Radix Vladimiriae), 10 grams of Rhizoma Acori Graminei, 10 grams of Rhizoma Cyperis, 12 grams, Poria, 6 grams of Fructus Aurantii Immaturuss, 5 grams of Quartz Albums, 4 grams of Caulis seu Radix Schisandrae Henryi, insert in container, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merge filtrate twice, concentrated.
Be used for the treatment of alzheimer disease.Oral, two doses of every days.
Embodiment 2
Take: 10 grams of the Rhizoma Pinelliaes, 8 grams of the Radixs Astragali, 12 grams of Rhizoma Chuanxiongs, 10 grams of Arisaema Cum Bile, 9 grams of Radix Curcumaes, 9 grams of Radix Aucklandiae (Radix Vladimiriae), 10 grams of Rhizoma Acori Graminei, 10 grams of Rhizoma Cyperis, 12 grams, Poria, 6 grams of Fructus Aurantii Immaturuss, 5 grams of Quartz Albums, 4 grams of Caulis seu Radix Schisandrae Henryi, insert in container, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Filtering residue adds 2 times of water gagings, decocts 1 hour, filters; Merge three times filtrate, concentrated.
Be used for the treatment of alzheimer disease.Oral, two doses of every days.
Embodiment 3
Take: 10 grams of the Rhizoma Pinelliaes, 8 grams of the Radixs Astragali, 12 grams of Rhizoma Chuanxiongs, 10 grams of Arisaema Cum Bile, 9 grams of Radix Curcumaes, 9 grams of Radix Aucklandiae (Radix Vladimiriae), 10 grams of Rhizoma Acori Graminei, 10 grams of Rhizoma Cyperis, 12 grams, Poria, 6 grams of Fructus Aurantii Immaturuss, 5 grams of Quartz Albums, 4 grams of Caulis seu Radix Schisandrae Henryi, insert in container, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merge filtrate twice, concentrated.
Be used for the treatment of alzheimer disease.Oral, two doses of every days.
Obviously, the above embodiment of the present invention is only for example of the present invention is clearly described, and is not the restriction to embodiments of the present invention.For one skilled in the art, can also make other changes in different forms on the basis of the above description.Here cannot give exhaustive to all embodiments.Everyly belong to apparent variation or the still row in protection scope of the present invention of variation that technical scheme of the present invention extends out.
Claims (8)
1. one kind is used for the treatment of the Chinese medicine of alzheimer disease, it is characterized in that, be prepared from by the medical material of following weight proportion: 8～10 grams of the Rhizoma Pinelliaes, 8～10 grams of the Radixs Astragali, 10～12 grams of Rhizoma Chuanxiongs, 8～10 grams of Arisaema Cum Bile, 7～9 grams of Radix Curcumaes, 7～9 grams of Radix Aucklandiae (Radix Vladimiriae), 8～10 grams of Rhizoma Acori Graminei, 8～10 grams of Rhizoma Cyperis, 10～12 grams, Poria, 5～6 grams of Fructus Aurantii Immaturuss, 0～5 gram of Quartz Album, 0～4 gram of Caulis seu Radix Schisandrae Henryi.
2. a kind of Chinese medicine that is used for the treatment of alzheimer disease according to claim 1, it is characterized in that, be prepared from by the medical material of following weight proportion: 10 grams of the Rhizoma Pinelliaes, 8 grams of the Radixs Astragali, 12 grams of Rhizoma Chuanxiongs, 10 grams of Arisaema Cum Bile, 9 grams of Radix Curcumaes, 9 grams of Radix Aucklandiae (Radix Vladimiriae), 10 grams of Rhizoma Acori Graminei, 10 grams of Rhizoma Cyperis, 12 grams, Poria, 6 grams of Fructus Aurantii Immaturuss.
3. a kind of Chinese medicine that is used for the treatment of alzheimer disease according to claim 1, it is characterized in that, be prepared from by the medical material of following weight proportion: 10 grams of the Rhizoma Pinelliaes, 8 grams of the Radixs Astragali, 12 grams of Rhizoma Chuanxiongs, 10 grams of Arisaema Cum Bile, 9 grams of Radix Curcumaes, 9 grams of Radix Aucklandiae (Radix Vladimiriae), 10 grams of Rhizoma Acori Graminei, 10 grams of Rhizoma Cyperis, 12 grams, Poria, 6 grams of Fructus Aurantii Immaturuss, 4 grams of Caulis seu Radix Schisandrae Henryi.
4. a kind of Chinese medicine that is used for the treatment of alzheimer disease according to claim 1, it is characterized in that, be prepared from by the medical material of following weight proportion: 10 grams of the Rhizoma Pinelliaes, 8 grams of the Radixs Astragali, 12 grams of Rhizoma Chuanxiongs, 10 grams of Arisaema Cum Bile, 9 grams of Radix Curcumaes, 9 grams of Radix Aucklandiae (Radix Vladimiriae), 10 grams of Rhizoma Acori Graminei, 10 grams of Rhizoma Cyperis, 12 grams, Poria, 6 grams of Fructus Aurantii Immaturuss, 5 grams of Quartz Albums.
5. a kind of Chinese medicine that is used for the treatment of alzheimer disease according to claim 1, it is characterized in that, be prepared from by the medical material of following weight proportion: 10 grams of the Rhizoma Pinelliaes, 8 grams of the Radixs Astragali, 12 grams of Rhizoma Chuanxiongs, 10 grams of Arisaema Cum Bile, 9 grams of Radix Curcumaes, 9 grams of Radix Aucklandiae (Radix Vladimiriae), 10 grams of Rhizoma Acori Graminei, 10 grams of Rhizoma Cyperis, 12 grams, Poria, 6 grams of Fructus Aurantii Immaturuss, 5 grams of Quartz Albums, 4 grams of Caulis seu Radix Schisandrae Henryi.
6. one kind is used for the treatment of the preparation method of the Chinese medicine of alzheimer disease, it is characterized in that, comprise the steps: to take the Rhizoma Pinelliae, the Radix Astragali, Rhizoma Chuanxiong, Arisaema Cum Bile, Radix Curcumae, Radix Aucklandiae (Radix Vladimiriae), Rhizoma Acori Graminei, Rhizoma Cyperi, Poria, Fructus Aurantii Immaturus, Quartz Album, Caulis seu Radix Schisandrae Henryi, insert in container, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell.
7. the preparation method of a kind of Chinese medicine that is used for the treatment of alzheimer disease according to claim 6, it is characterized in that, comprise the steps: to take the Rhizoma Pinelliae, the Radix Astragali, Rhizoma Chuanxiong, Arisaema Cum Bile, Radix Curcumae, Radix Aucklandiae (Radix Vladimiriae), Rhizoma Acori Graminei, Rhizoma Cyperi, Poria, Fructus Aurantii Immaturus, Quartz Album, Caulis seu Radix Schisandrae Henryi, insert in container, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, dry, then add appropriate dextrin and correctives, granulate according to this area common process.
8. the preparation method of a kind of Chinese medicine that is used for the treatment of alzheimer disease according to claim 6, it is characterized in that, comprise the steps: to take the Rhizoma Pinelliae, the Radix Astragali, Rhizoma Chuanxiong, Arisaema Cum Bile, Radix Curcumae, Radix Aucklandiae (Radix Vladimiriae), Rhizoma Acori Graminei, Rhizoma Cyperi, Poria, Fructus Aurantii Immaturus, Quartz Album, Caulis seu Radix Schisandrae Henryi, insert in container, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, concentrated, dry, pulverize.
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| CN104524447A (en) * | 2014-12-21 | 2015-04-22 | 秦文官 | Traditional Chinese medicine capsule for treating senile dementia and preparation method of traditional Chinese medicine capsule |
| CN105748851A (en) * | 2016-03-15 | 2016-07-13 | 庄亮 | Medicine for treating Alzheimer disease |
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| CN1857666A (en) * | 2006-03-14 | 2006-11-08 | 王信锁 | Chinese medicine preparation for treating senile dementia |
| KR20120060678A (en) * | 2010-12-02 | 2012-06-12 | 문경시 | Composition for treating and preventing Alzheimer's disease containing extract of Schizandra seed |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104524447A (en) * | 2014-12-21 | 2015-04-22 | 秦文官 | Traditional Chinese medicine capsule for treating senile dementia and preparation method of traditional Chinese medicine capsule |
| CN105748851A (en) * | 2016-03-15 | 2016-07-13 | 庄亮 | Medicine for treating Alzheimer disease |
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