CN103908623A - Rhizoma atractylodis macrocephalae stomach-nourishing granules and preparation method thereof - Google Patents
Rhizoma atractylodis macrocephalae stomach-nourishing granules and preparation method thereof Download PDFInfo
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- CN103908623A CN103908623A CN201410158593.4A CN201410158593A CN103908623A CN 103908623 A CN103908623 A CN 103908623A CN 201410158593 A CN201410158593 A CN 201410158593A CN 103908623 A CN103908623 A CN 103908623A
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Abstract
The invention provides rhizoma atractylodis macrocephalae stomach-nourishing granules and a preparation method thereof, belongs to a health food for humans, and in particular relates to a health food prepared from rhizoma atractylodis macrocephalae as a main raw material and a preparation method of the health food. The granules are prepared from the following raw materials for preparing active components: rhizoma atractylodis macrocephalae, rhizoma cyperi, platycodon grandiflorum, yam, tangerine, astragalus membranaceus, fructus amomi, sealwort and liquorice. The preparation method comprises the following steps: (1) decocting and extracting the rhizoma atractylodis macrocephalae, the rhizoma cyperi, the platycodon grandiflorum, the yam, the tangerine, the astragalus membranaceus, the fructus amomi, the sealwort and the liquorice, drying the extract, and crushing for later use; and (2) uniformly mixing the backup materials, granulating, and drying. The rhizoma atractylodis macrocephalae stomach-nourishing granules have the advantages that the raw materials for preparing the active components are reasonable and scientific in compatibility, rich in nutrition and contain multiple beneficial substances required by a human body; the granules are a health food for strengthening spleen, harmonizing stomach, and improving gastrointestinal functions, and are particularly suitable for middle-aged and old people with epigastric discomfort, dyspepsia and inappetence.
Description
technical field:
A kind of Rhizoma Atractylodis Macrocephalae stomach nourishing granule and preparation method thereof, belongs to natural health care, the particularly health food take plant as raw material, and its preparation method.
background technology:
Along with the quickening of people's rhythm of life, living standard improves constantly, and because many people do not note healthy feed, most people gastrointestinal burden, exists subhealth state problem, address this problem, and needs strengthening the spleen and nourishing the stomach and improves gastrointestinal function.The medicine for the treatment of in the market gastropathy is a lot, but lacks very much but have the health food that improves gastrointestinal function and strengthening the spleen and nourishing the stomach function.
summary of the invention:
The problem to be solved in the present invention is exactly to provide a kind of health food that has invigorating the spleen and regulating the stomach, improves gastrointestinal function for above deficiency, and its preparation method.Its technical scheme is as follows:
The raw material of preparing its active component is the raw material of following weight portion:
Rhizoma Atractylodis Macrocephalae 15-25, Rhizoma Cyperi 10-15, Radix Platycodonis 15-25, Rhizoma Dioscoreae 15-25, Exocarpium Citri Rubrum 10-15, Radix Astragali 10-15, Fructus Amomi 10-15, Rhizoma Polygonati 10-25, Radix Glycyrrhizae 10-15.
Its preparation method comprises the following steps:
1) by Rhizoma Atractylodis Macrocephalae 15-25, Rhizoma Cyperi 10-15, Radix Platycodonis 15-25, Rhizoma Dioscoreae 15-25, Exocarpium Citri Rubrum 10-15, Radix Astragali 10-15, Fructus Amomi 10-15, Rhizoma Polygonati 10-25, Radix Glycyrrhizae 10-15.Extracting in water three times, filters, and filtrate is concentrated, dry, pulverize for subsequent use;
2), by above-mentioned fine powder mix homogeneously, granulate, be dried.
The characteristic and the function that have for raw material of the present invention are:
the Rhizoma Atractylodis Macrocephalae: meridian distribution of property and flavor: bitter, sweet, temperature.Return spleen, stomach warp.The Rhizoma Atractylodis Macrocephalae has invigorating the spleen and benefiting QI, dampness diuretic, and hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
1. the pharmacological action relevant to effect: the Rhizoma Atractylodis Macrocephalae has invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement." medicine origin " is recorded: " dehumidifying benefit is dry, and middle QI invigorating, and warming middle-JIAO goes to wet in taste, and except gastric heat, strong taste, enter diet, quench the thirst, antiabortive.”
2.drug action
:for weakness of the spleen and stomach, lack of appetite distension, fatigue and weakness, has loose bowels.Tonifying the spleen and stomach can with the compatibility such as Radix Codonopsis, Radix Glycyrrhizae; The painful abdominal mass that disappears de-swelling can be equal to use with Fructus Aurantii; The spleen strengthening and damp drying antidiarrheal can be equal to use with Pericarpium Citri Reticulatae, Poria.
rhizoma Cyperi:pungent, the micro-hardship of Rhizoma Cyperi, micro-sweet, flat, enters liver taste tri-jiao channel, function dispersing the stagnated live-QI to relieve the stagnation of QI, menstruction regulating and pain relieving, regulates the flow of vital energy and adjusts.Modern pharmacological research has:
1. antiinflammatory action: Singh N report, cyperol extract 100mg/kg lumbar injection, on Carrageenan and formaldehyde-caused rat swelling of the feet have obvious inhibitory action.This effect is better than 5-10mg/kg hydrocortisone.Gupta MB studies have shown that its anti-inflammatory component is triterpenoid compound.Wherein the antiinflammatory action of swelling of the feet due to composition IV-B on Carrageenan, stronger 8 times than hydrocortisone, large 3 times of safety range.PARA FORMALDEHYDE PRILLS(91,95) swelling of the feet also has inhibitory action.The ratio of the effect of gavage and lumbar injection is 1:3, and explanation may only partially absorb in digestive tract.
2. antibacterial action
:in vitro tests, Rhizoma Cyperi volatile oil has inhibitory action to staphylococcus aureus, invalid to other antibacterials.The bacteriostasis of cyperene I and II is stronger than volatile oil, and also effective to sonne bacillus.Hydrogenation does not affect its antibacterial action.Cyperone is completely invalid.Rhizoma Cyperi extract also has inhibitory action to some fungus.
radix Platycodonis: Radix Platycodonis bitter in the mouth, pungent, property is flat.Return lung meridian.Effect lung qi dispersing, sore-throat relieving, eliminate the phlegm, evacuation of pus.1 modern pharmacological research shows that Radix Platycodonis is still regulated the flow of vital energy, invigorates blood circulation, helped digestion, sedative action
2 modern pharmacological researches: Radix Platycodonis eliminates the phlegm, antitussive, antiasthmatic effect; The water of Radix Platycodonis and alcohol extract all have hypoglycemic activity; Slightly carry kikyosaponin and have the effect that suppresses rat gastric secretion and anti-peptic ulcer; Radix Platycodonis has antiinflammatory and immunological enhancement; Radix Platycodonis has the effect of the cholesterol of reduction; Kikyosaponin can increase cholic acid secretion, reduces the cholesterol level in rat liver, increases the discharge of steroid; Radix Platycodonis has calmness, analgesia, refrigeration function; Kikyosaponin has local excitation and great haemolysis; The thick Saponin of Radix Platycodonis reduces blood pressure, decreased heart rate, inhibition Repiration; Radix Platycodonis has antibacterial action, and multiple coccus, bacillus and acrothesium floccosum are had to inhibitory action; Radix Platycodonis has the effect that intestinal tube shrinks that suppresses; Radix Platycodonis has inducing diuresis to remove edema, antiallergic, antitumor action.
rhizoma Dioscoreae: sweet in the mouth, property are put down, and enter lung, spleen, kidney channel; Not dry oiliness.There is strengthening the spleen and tonifying the lung, stomach reinforcing the kidney invigorating, the benefit of reinforcing the kidney essence, hearing-improing and eyesight improving, help the five internal organs, bone and muscle strengthening, grow that will is calmed the nerves, effect of life lengthening.
Invigorating spleen and reinforcing stomach, aid digestion:
Rhizoma Dioscoreae contains the material such as amylase, polyphenol oxidase, is conducive to taste digestive and absorptive functions, is the product of the medicine-food two-purpose of flat tonifying the spleen and stomach simply.No matter spleen sun loses or deficiency of stomach-YIN, all edible.With controlling, weakness of the spleen and stomach, lack of appetite body are tired, the disease such as have loose bowels together for normal and gastrointestinal drink clinically.
exocarpium Citri Rubrum:" medicine justice ": Exocarpium Citri Rubrum, pungently can walk crosswise eliminating stagnation, the bitter decline of keeping straight on, is promoting the circulation of QI spleen invigorating key medicine in managing.Lid is controlled expectorant and must be regulated the flow of vital energy, the spontaneous recovery of diarrhea due to disorder of QI expectorant, thus with entering lung spleen, main all expectorant diseases, merit occupies on all expectorant medicines.There is the good effect of flat stomach lung heat clearing spleen invigorating.
the Radix Astragali: the Radix Astragali: nature and flavor: sweet, tepor.Gui Jing: return lung, spleen, liver, kidney channel.Effect: the Radix Astragali has that benefiting QI for strengthening the superficies, arresting sweating are admittedly de-, effect of spleen invigorating, inducing diuresis to remove edema.Be used for the treatment of the deficiency of vital energy weak, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, carbuncle is difficult bursts, and burst and do not hold back for a long time, blood deficiency and yellow complexion, interior-heat is quenched one's thirst, chronic gastritis, albuminuria, diabetes etc.The invigorating middle warmer of Radix Astragali Preparata QI invigorating, raw by consolidating superficial resistance holder skin ulcer.
Invigorating the spleen and replenishing QI: the diseases such as tired unable, the gastroptosis of weakness of the spleen and stomach, inappetence, anorexia and loose stool, limb are had to good efficacy.
fructus Amomi:meridian distribution of property and flavor: pungent, temperature.Return spleen, stomach, kidney channel.Function cures mainly: removing dampness appetizing, and warming spleen and stopping diarrha, regulate the flow of vital energy antiabortive.The pharmacological action of Fructus Amomi: 1, the effect on digestive system: the impact on intestine in vitro smooth muscle: get one section of rat, Cavia porcellus or rabbit intestinal and put in tyrode's solution bath, record intestinal tube activity change by monitor, observe impact and antagonism acetylcholine and the BaCl2 effect of medicinal liquid on intestinal tube spontaneous activity.Result Fructus Amomi decoct (2.5-5 × 10(-3) g crude drug/ml) time, can make Cavia porcellus, rat small intestine intestinal tube shrink and strengthen, when escalated dose, intestinal tube is had to inhibitory action, performance tension force reduces, and amplitude reduces.The rat small intestine intestinal tube tonicity that Fructus Amomi decoct causes acetylcholine and barium chloride, tetanic property is shunk partial inhibition.Fructus Amomi (1.3 × l0(-3) g crude drug/ml) volatility position can make rabbit intestinal tube slightly excited, then proceed to obvious inhibitory action, tension force reduces, and contraction frequency slows down, amplitude reduces, and with concentration difference intestinal tube excitement or spasm that partially or completely antagonism acetylcholine, BaCl2 cause.Modern Chinese medicine treatment gastropathy common medicine, is mainly used in: for taste retention of damp leading to blockage of QI, gastral cavity abdominal distention is vexed, and vomiting is eaten less, greasy fur; Deficiency and coldness of spleen and stomach, the symptoms such as vomiting and diarrhoea.
rhizoma Polygonati:have and promote the production of body fluid, the effect of tonifying the spleen and stomach.Nourishing kidney lung moistening, invigorating the spleen and replenishing QI, bone and muscle strengthening.Control deficient cold and heat, pulmonary tuberculosis hemoptysis, the empty lack of appetite of body after being ill, muscles and bones weakness, rheumatalgia, wind favus disease; Control insufficiency of the spleen yellowish complexion, cough due to deficiency of the lung, muscles and bones acid numbness is unable.
In addition, Rhizoma Polygonati is restrained astringent or styptic treatment for spontaneous sweating in addition, supplementing QI for promoting the production of body fluid, the effect of kidney calming.For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, the deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia.Rhizoma Polygonati contains abundant organic acid, vitamin, flavonoid, phytosterol and has the lignan of potent reactivation, the strong liver of energy QI invigorating, the efficiency of promoting cells exclude refuse, supply more oxygen, construction and uses energy, raising memory and sexual function.
radix Glycyrrhizae:there is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the effect of coordinating the actions of various ingredients in a prescription.
Compared with prior art advantage of the present invention is: above each material combination, produce good synergism, and the product of making has invigorating the spleen and regulating the stomach, improves the health care of gastrointestinal function.
For show product of the present invention to invigorating the spleen and regulating the stomach, improve the effect of gastrointestinal function, to 100 ages between 35-70 year, done the observation of system without the experimenter of the serious primary disease such as cardiovascular, liver, kidney, tested crowd takes the symptom of the front tool taste of product of the present invention and gastrointestinal function discomfort, as gastral cavilty flatulence, dyspepsia, lethargy, appetite depression, constipation or rare half congealed.
Instructions of taking: each serving with one bag of granule (8 grams), every day secondary.Viewing duration, experimenter need keep reasonable diet structure and work rest program.
Time of Administration: 30 days.
Effectively standard:
Gastrointestinal function improves arm's length standard: appetite is normal, and spirit is happy, and Weichangshu is suitable, and digestive function of spleen and stomach is good, and stool forms rule.
Return feedback result: after 30 days, in 100 experimenters, have 99 appetite normal, spirit is happy, and Weichangshu is suitable, and digestive function of spleen and stomach is good, and stool forms rule.Invigorating the spleen and regulating the stomach, improve gastrointestinal function effective percentage and reach 99%.
accompanying drawing explanation:
Fig. 1 is production technological process of the present invention.
the specific embodiment:
Embodiment mono-:
Take each raw material by following weight parts:
15 parts of the Rhizoma Atractylodis Macrocephalaes, Rhizoma Cyperi part, 15 parts of Radix Platycodoniss, 15 parts of Rhizoma Dioscoreaes, 10 parts of Exocarpium Citri Rubrums, 10 parts of the Radixs Astragali, 10 parts of Fructus Amomis, 10 parts of Rhizoma Polygonatis, 10 parts, Radix Glycyrrhizae.
Its preparation method comprises the following steps:
1) 10 parts of 15 parts of the Rhizoma Atractylodis Macrocephalaes, Rhizoma Cyperi part, 15 parts of Radix Platycodoniss, 15 parts of Rhizoma Dioscoreaes, 10 parts of Exocarpium Citri Rubrums, 10 parts of the Radixs Astragali, 10 parts of Fructus Amomis, 10 parts of Rhizoma Polygonatis, Radix Glycyrrhizae are added to 6 times of water gagings, decoct and extract 3 times, each 3 hours, 100 order filter-cloth filterings, merging filtrate, is condensed into filtrate the extractum of relative density 1.20, is 70 ℃～80 ℃ in temperature, vacuum be under the condition of 0.08～0.1Mpa by extract dry, be ground into 150 order fine powders for subsequent use;
2) by above-mentioned fine powder mix homogeneously, granulate, dry pack and get final product.
Embodiment bis-:
Take each raw material by following weight parts:
25 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of Rhizoma Cyperis, 25 parts of Radix Platycodoniss, 25 parts of Rhizoma Dioscoreaes, 15 parts of Exocarpium Citri Rubrums, 10 parts of the Radixs Astragali, 10 parts of Fructus Amomis, 25 parts of Rhizoma Polygonatis, 15 parts, Radix Glycyrrhizae.
Its preparation method comprises the following steps:
1) 15 parts of 25 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of Rhizoma Cyperis, 25 parts of Radix Platycodoniss, 25 parts of Rhizoma Dioscoreaes, 15 parts of Exocarpium Citri Rubrums, 10 parts of the Radixs Astragali, 10 parts of Fructus Amomis, 25 parts of Rhizoma Polygonatis, Radix Glycyrrhizae are added to 8 times of water gagings, decoct and extract 3 times, each 2 hours, 150 order filter-cloth filterings, merging filtrate, is condensed into filtrate the extractum of relative density 1.25, is 70 ℃～80 ℃ in temperature, vacuum be under the condition of 0.08～0.1Mpa by extract dry, be ground into 200 order fine powders for subsequent use;
2), by above-mentioned fine powder mix homogeneously, granulate, be dried pack and get final product.
Embodiment tri-:
Take each raw material by following weight parts:
20 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of Rhizoma Cyperis, 20 parts of Radix Platycodoniss, 20 parts of Rhizoma Dioscoreaes, 10 parts of Exocarpium Citri Rubrums, 15 parts of the Radixs Astragali, Fructus Amomi part 15,20 parts of Rhizoma Polygonatis, 10 parts, Radix Glycyrrhizae.
Its preparation method comprises the following steps:
1) 10 parts of 20 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of Rhizoma Cyperis, 20 parts of Radix Platycodoniss, 20 parts of Rhizoma Dioscoreaes, 10 parts of Exocarpium Citri Rubrums, 15 parts of the Radixs Astragali, Fructus Amomi part 15,20 parts of Rhizoma Polygonatis, Radix Glycyrrhizae are added to 7 times of water gagings, decoct and extract 2 times, each 2.5 hours, 120 order filter-cloth filterings, merging filtrate, is condensed into filtrate the extractum of relative density 1.20, is 70 ℃～80 ℃ in temperature, vacuum be under the condition of 0.08～0.1Mpa by extract dry, be ground into 180 order fine powders for subsequent use;
3), by above-mentioned fine powder mix homogeneously, granulate, be dried pack.
Claims (2)
1. a Rhizoma Atractylodis Macrocephalae stomach nourishing granule, the raw material that it is characterized in that preparing its active component is the raw material of following weight portion:
Rhizoma Atractylodis Macrocephalae 15-25, Rhizoma Cyperi 10-15, Radix Platycodonis 15-25, Rhizoma Dioscoreae 15-25, Exocarpium Citri Rubrum 10-15, Radix Astragali 10-15, Fructus Amomi 10-15, Rhizoma Polygonati 10-25, Radix Glycyrrhizae 10-15.
2. the preparation method of Rhizoma Atractylodis Macrocephalae stomach nourishing granule described in claim 1, is characterized in that comprising the following steps:
1), by Rhizoma Atractylodis Macrocephalae 15-25, Rhizoma Cyperi 10-15, Radix Platycodonis 15-25, Rhizoma Dioscoreae 15-25, Exocarpium Citri Rubrum 10-15, Radix Astragali 10-15, Fructus Amomi 10-15, Rhizoma Polygonati 10-25, Radix Glycyrrhizae 10-15, extracting in water three times, filters, and filtrate is concentrated, dry, pulverize for subsequent use; 2), by above-mentioned fine powder mix homogeneously, granulate, be dried.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104082487A (en) * | 2014-08-01 | 2014-10-08 | 方瑞祥 | Health tea capable of relaxing bowels |
| CN104738262A (en) * | 2015-03-12 | 2015-07-01 | 林凡清 | Stomach nourishing tea |
| CN109224052A (en) * | 2018-11-14 | 2019-01-18 | 湖北鼎世立华生物科技有限公司 | A kind of composition and preparation improving children's spleen and gastrointestinal tract and growth and development |
-
2014
- 2014-04-21 CN CN201410158593.4A patent/CN103908623A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104082487A (en) * | 2014-08-01 | 2014-10-08 | 方瑞祥 | Health tea capable of relaxing bowels |
| CN104738262A (en) * | 2015-03-12 | 2015-07-01 | 林凡清 | Stomach nourishing tea |
| CN109224052A (en) * | 2018-11-14 | 2019-01-18 | 湖北鼎世立华生物科技有限公司 | A kind of composition and preparation improving children's spleen and gastrointestinal tract and growth and development |
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