CN103893415A - Medicine for treating irregular menstruation and preparation method thereof - Google Patents
Medicine for treating irregular menstruation and preparation method thereof Download PDFInfo
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Abstract
The invention disclosed a medicine for treating irregular menstruation and a preparation method thereof, and belongs to the field of traditional Chinese medicines. The effective part of the medicine comprises the materials of: herb of Japanese conehead, leaves of himalayan prinsepia, hawthorn, rodgersia pinnata, herb of sweet basil, iresine herbstii, vervain, root of angelica nitida, begonia, cassia bark, pine needle, lettuce, pomegranate bark, tetrapanax papyriferus, root of David currant and osbeckia chinensis; the medicine is proper in compatibility of materials, accords with principles of traditional Chinese medicine and modern medicine and pharmacology, has the effects on supporting body resistance, activating Qi to resolve stagnation and relieve swelling and pain, also has obvious curative effect for irregular menstruation, and is convenient to take, safe and reliable, and free from toxic and side effects; people can work and live a normal life when taking the medicine; the medicine is short in course of treatment, rapid in effect and free from relapse after curing, thus being suitable for widely applied.
Description
Affiliated technical field
The present invention relates to the field of Chinese medicines, relate in particular to a kind of medicine and preparation method for the treatment of menoxenia.
Background technology
Menstruation is a kind of normal physiological phenomenon of women, affects because it is subject to inside and outside various factors, and therefore, each woman's the menstruation form of expression is also not quite similar, and due to pathology reason, usually shows as menoxenia.Menoxenia refers to that menstruation loses normal regularity, and most women had the experience of opsomenorrhea, month infrequent menstruation or menstruation irregularis.A variety of situations can cause menoxenia, as the imbalance of the improvement of pregnancy, stress, fat-reducing, life style, hormone, infection, tumor etc.Women's menstrual cycle has very large individual variation, and menstrual cycle is few to 20 days, nearly 36 days, all calculates normal during this.But the gap periods of each menstruation is irregular in advance or to delay be all abnormal, is exactly so-called menoxenia.
Differential diagnosis in tcm thinks that menoxenia has following several situation, and delayed menstrual cycle and hypomenorrhea often lost blood by prolonged illness or consume puerperal and hinder essence and blood, or insufficiency of the spleen nutrient blood are empty few; Or congenital defect, the voluminous exhaustion due to sexual indulgence consumption essence of being impairment of the kidney, the punching of suffering from a deficiency of the kidney is appointed and is not filled; Or menstruation eating cold and uncooked food excessively or impression cold, blood is cold coagulation; Spirit depressing, feelings will is not smooth, and stagnation of QI blood stagnation etc. causes.
Blood-deficiency type menoxenia: disease is seen delayed menstrual cycle, the few color of amount is light, and matter is rare clearly, with dizzy, insomnia, cardiopalmus, pale complexion, spiritlessness and weakness, light red tongue, weak pulse is unable.
Renal deficiency type menoxenia: disease sees that menarche is slower, and delay menstrual period, amount is few, and color is normal or dim, and matter is thin, and with sore waist and aching in the waist and the back, tongue is normal or partially light, deep pulse.
Blood-cold type menoxenia: disease is seen delayed menstrual cycle, the few color of amount is dark, have piece, or the light matter of color is rare, with cold and pain in the lower abdomen, likes warm pain relieved by pressing, obtain hotly to subtract, or aversion to cold and cold limbs, clear urine in large amounts, defecates thin, light red tongue, white and thin fur, deep and tense pulse or heavy unable late.
Type of depression of QI menoxenia: disease is seen delayed menstrual cycle, the few color of amount secretly has piece, discharge not smooth, with distention and pain in the lower abdomen, mammary swelling hypochondriac pain, spirit depressing, tongue normally or slightly dark, stringy and hesitant pulse.
The menstrual onset time is irregular, has had a strong impact on the women of child-bearing age's quality of life.Chinese medicine thinks that treatment menoxenia need to be by slowly taking good care of, and present most prescription is all to suit the remedy to the case for different people, and treatment cycle is long, easily recurs, and curative effect is not obvious; Can not fundamentally start with from endocrine regulation, therapeutic scheme cost is high, and wound body, easily recurrence, and curative effect is not obvious.
Summary of the invention
The invention provides a kind of medicine and preparation method for the treatment of menoxenia; The selected medical material compatibility of medicine of the present invention is suitable, meet Chinese medicine and pharmacy and modern medicine theory, and there is effect of the body resistance strengthening and constitution consolidating, benefiting QI and nourishing blood, circulation of qi promoting dissipating blood stasis, reducing swelling and alleviating pain, treatment menoxenia is had to significant curative effect, taking convenience, safe and reliable, have no side effect, period in a medicine can normally be worked and live, short treating period, instant effect, non-relapse after healing, application should be widely promoted.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a medicine for menoxenia, raw material composition and the parts by weight of making described effective ingredient are:
23～47 parts of 26～50 parts of Serpentis pimples of 27～51 portions of Fructus Crataegis of 30～53 portions of Folium Prinsepiae Utilis of Herba Strobilanthis Japonici
16～40 parts of 18～42 parts of Angelica niyida Wolff[A. ching-haiensis Shan xe K. T. Fus of 21～43 portions of Herba Verbenae of 23～47 parts of Herba Iresines Herbstiis of Herba Ocimi (Herba Ocimi Pilosi)
13～37 parts, 14～38 portions of Caulis et Folium Lactucae sativaes of 15～39 parts of Folium Pinis of 15～39 portions of Cortex Cinnamomis of Flos Begoniae Evansianae
11～29 parts of 11～33 parts of Herba Osbeckiaes of 12～36 parts of Radix Ribis davidiis of 12～36 portions of Medulla Tetrapanaciss of Pericarpium Granati.
Raw material composition and the parts by weight of making described effective ingredient are:
27～43 parts of 30～46 parts of Serpentis pimples of 31～47 portions of Fructus Crataegis of 34～49 portions of Folium Prinsepiae Utilis of Herba Strobilanthis Japonici
20～36 parts of 22～38 parts of Angelica niyida Wolff[A. ching-haiensis Shan xe K. T. Fus of 25～39 portions of Herba Verbenae of 27～43 parts of Herba Iresines Herbstiis of Herba Ocimi (Herba Ocimi Pilosi)
17～33 parts, 18～34 portions of Caulis et Folium Lactucae sativaes of 19～35 parts of Folium Pinis of 19～35 portions of Cortex Cinnamomis of Flos Begoniae Evansianae
14～26 parts of 14～30 parts of Herba Osbeckiaes of 16～32 parts of Radix Ribis davidiis of 16～32 portions of Medulla Tetrapanaciss of Pericarpium Granati.
Raw material composition and the parts by weight of making described effective ingredient are:
31～39 parts of 34～42 parts of Serpentis pimples of 35～43 portions of Fructus Crataegis of 38～45 portions of Folium Prinsepiae Utilis of Herba Strobilanthis Japonici
24～32 parts of 26～34 parts of Angelica niyida Wolff[A. ching-haiensis Shan xe K. T. Fus of 28～36 portions of Herba Verbenae of 31～39 parts of Herba Iresines Herbstiis of Herba Ocimi (Herba Ocimi Pilosi)
21～29 parts, 22～30 portions of Caulis et Folium Lactucae sativaes of 23～31 parts of Folium Pinis of 23～31 portions of Cortex Cinnamomis of Flos Begoniae Evansianae
17～23 parts of 18～26 parts of Herba Osbeckiaes of 20～28 parts of Radix Ribis davidiis of 20～28 portions of Medulla Tetrapanaciss of Pericarpium Granati.
Raw material composition and the parts by weight of making described effective ingredient are:
35 parts of 38 parts of Serpentis pimples of 39 portions of Fructus Crataegis of 41 portions of Folium Prinsepiae Utilis of Herba Strobilanthis Japonici
28 parts of 30 parts of Angelica niyida Wolff[A. ching-haiensis Shan xe K. T. Fus of 32 portions of Herba Verbenae of 35 parts of Herba Iresines Herbstiis of Herba Ocimi (Herba Ocimi Pilosi)
25 parts, 26 portions of Caulis et Folium Lactucae sativaes of 27 parts of Folium Pinis of 27 portions of Cortex Cinnamomis of Flos Begoniae Evansianae
20 parts of 22 parts of Herba Osbeckiaes of 24 parts of Radix Ribis davidiis of 24 portions of Medulla Tetrapanaciss of Pericarpium Granati.
Treat a preparation method for the medicine of menoxenia, comprise following processing step:
(1) Herba Strobilanthis Japonici, Folium Prinsepiae Utilis, Angelica niyida Wolff[A. ching-haiensis Shan xe K. T. Fu, Flos Begoniae Evansianae, Cortex Cinnamomi, Caulis et Folium Lactucae sativae, Pericarpium Granati, Medulla Tetrapanacis and Radix Ribis davidii are cleaned, put into container, add the distilled water of 8～10 times of amounts, soak after 5～6 hours, boil 3～4 hours, extract; Again add 6～8 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, the thick paste that at 60 DEG C of simmer down tos, relative density is 1.10～1.13, for subsequent use;
(2) Fructus Crataegi, Herba Ocimi (Herba Ocimi Pilosi), Herba Iresines Herbstii and Herba Verbenae are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(3) Serpentis pimple and Folium Pini are put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(4) Herba Osbeckiae is cleaned, immersed 80% the alcohol solution dipping 1～2 hour of 5 times of amounts, heating extraction 3 hours, reclaims ethanol, filters, and obtains filtrate, and the thick paste that at 65 DEG C of simmer down tos, relative density is 1.12～1.16 is for subsequent use;
(5) above-mentioned steps (1)～(4) prepared thick paste, juice and fine powder are mixed, make medicated powder granule, obtain the medicine for the treatment of menoxenia of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Herba Strobilanthis Japonici: acrid in the mouth, micro-hardship, property is micro-wet; Return liver, spleen channel.Promoting blood circulation to restore menstrual flow, blood stasis dispelling row water.Main menoxenia, dysmenorrhea, amenorrhea, puerperal abdonimal pain, lump in the abdomen, body and face edema, carbuncle, swollen plays damage." Chinese herbal medicine is commonly used in Sichuan " carries: " the capable water of repercussive, soothing liver-QI is loose strongly fragrant.Control menoxenia, puerperal dripping stomachache, bruise, lump in the abdomen carbuncle, traumatic injury and body and face edema.”
Folium Prinsepiae Utilis: bitter in the mouth, pungent, cool in nature; GUIXIN, liver, kidney channel.Heat-clearing and toxic substances removing, promoting blood circulation and detumescence.For lymphadenitis, parotitis, mastitis, rheumatic arthritis, hemorrhoid, traumatic injury, menoxenia, anemia, gingival hemorrhage." Yunnan Chinese herbal medicine " carries: " blood circulation promoting and blood stasis dispelling, synthetism detumescence, tonify deficiency.”
Fructus Crataegi: sour in the mouth, sweet, slightly warm in nature; Return spleen, stomach, Liver Channel.Promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis.For meat stagnation, gastral cavilty distension, dysentery stomachache, blood stasis amenorrhea, postpartum stagnation, trusted subordinate's twinge, hernia pain; Hyperlipemia.The effect of Fructus Crataegi (parched to brown) dyspepsia and intestinal stasis relieving strengthens.For meat stagnation, dysentery is not well." detailed outline " carries: " dissipating fluid-retention food, the meat Ji ， mass in the abdomen that disappears, phlegm retention feeling of fullness acid regurgitation, stagnant blood pain with distension.”
Serpentis pimple: bitter in the mouth, micro-sweet, puckery, property is flat.Anti-inflammtory anti-dysentery, menstruction regulating and pain relieving, hemostasis.For enteritis, bacillary dysentery, menoxenia, dysmenorrhea, rheumatalgia, fracture, traumatic injury swelling and pain due to blood stasis.
Herba Ocimi (Herba Ocimi Pilosi): acrid in the mouth, sweet, warm in nature; Return lung, spleen, stomach, large intestine channel.Dispelling wind circulation of qi promoting, removing dampness helps digestion, invigorates blood circulation, removing toxic substances.Control headache due to invasion of exogenous pathogens, the flatulence due to improper diet stagnation of QI, gastralgia, has loose bowels, menoxenia, traumatic injury, snake bite and insect sting, skin eczema, urticaria pruritus.Guangzhou army " conventional Chinese herbal medicine handbook " carries: " detumescence of dispeling the wind, eliminating stasis to stop pain.Control flatulence, dyspepsia, stomachache, enteritis, diarrhea, affection of exogenous wind-cold, headache, chest pain, traumatic injury congestive edema, rheumatic arthralgia, eczematous dermatitis.”
Herba Iresines Herbstii: sweet in the mouth, micro-hardship; Cool in nature; Return liver, large intestine channel.Cooling blood for hemostasis, clearing away heat-damp and promoting diuresis, removing toxic substances.Main haematemesis, epistaxis, hemoptysis, has blood in stool, metrorrhagia, dysentery, has loose bowels, damp-heat vaginal discharge, carbuncle." mountain of papers Chinese herbal medicine " carries: " relaxing muscles and tendons to promote blood circulation, menstruction regulating and pain relieving.Control menoxenia, epistaxis, dysmenorrhea, fracture.”
Herba Verbenae: bitter in the mouth, pungent, cold nature; Return liver, spleen channel.Heat-clearing and toxic substances removing, preventing the attack (or recurrence) of malaria parasite killing, inducing diuresis to remove edema, dissipating blood stasis stimulates the menstrual flow.Cure mainly malaria, schistosomicide, filaricide, cat fever, acute gastroenteritis, bacillary dysentery, hepatitis, cirrhotic ascites, oedema due to nephritis, urinary tract infection, scrotum swells and ache, menoxenia, blood stasis amenorrhea, periodontitis, diphtheria, laryngopharynx swelling and pain; Traumatic injury is controlled in external, furuncle swelling toxin.Modern medicine study confirmation, Herba Verbenae herb decoct all has inhibitory action to staphylococcus aureus, shigella flexneri, and 31 milligrams of/liter of concentration of its water decoction can be killed leptospira.
Angelica niyida Wolff[A. ching-haiensis Shan xe K. T. Fu: sweet in the mouth, pungent, warm in nature.Enrich blood, invigorate blood circulation, intestine moistening.Main blood deficiency disease, menoxenia, pain due to blood stasis, dryness of the intestine constipation.
Flos Begoniae Evansianae: sour in the mouth, puckery, cool in nature.Cooling blood for hemostasis, dissipating blood stasis, regulating menstruation.For spitting blood, epistaxis, hemoptysis, metrorrhagia, leucorrhea, menoxenia, dysentery; Traumatic injury is controlled in external.
Cortex Cinnamomi: acrid in the mouth, sweet, extremely hot in nature; Return kidney, spleen, the heart, Liver Channel.Mend fire supporing yang, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.For sexual impotence, cold womb, chills and pain of the waist and kness, suffers from a deficiency of the kidney and breathes heavily, dizziness due to yang deficiency, and conjunctival congestion pharyngalgia, trusted subordinate's cold type of pain, deficiency and coldness is vomited and diarrhoea, colic of cold type, renal mass, amenorrhea, dysmenorrhea.
Folium Pini: bitter in the mouth; Warm in nature, GUIXIN, spleen channel.Dispeiling pathogenic wind and removing dampness, killing parasites for relieving itching, blood-promoting and mind-easing.Cure mainly rheumatism flaccidity syndrome and arthralgia syndrome, beriberi, eczema, tinea, rubella pruritus, traumatic injury, neurasthenia, chronic nephritis, hypertension.Can be used for preventing encephalitis, influenza.
Caulis et Folium Lactucae sativae: bitter in the mouth, sweet, cool in nature; Return stomach, small intestine meridian.Diuresis lactogenesis, heat-clearing and toxic substances removing.Cure mainly dysuria, hematuria, galactostasis, worm venom, toxic swelling." daily book on Chinese herbal medicine " carries: " sharp the five internal organs, mend muscles and bones, open heat of the diaphragm, qualcomm meridian, removing foul breath, white teeth, bright eyes.”
Pericarpium Granati: sour in the mouth, puckery, warm in nature; Return large intestine channel.Relieving diarrhea with astringents, hemostasis anthelmintic.For chronic diarrhea, chronic dysentery, has blood in stool, proctoptosis, metrorrhagia, leucorrhea, abdominal pain due to worm stagnation.Pharmacological evaluation shows, 2-acetonylpiperidine has very strong killing power to cestode, decoct is to diphtheria corynebacterium, staphylococcus aureus, Shi Shi and shigella flexneri, Bacillus proteus, vibrio cholera, Bacillus typhi, bacillus pyocyaneus and tubercule bacillus etc. have obvious inhibitory action, also inhibited to 10 kinds of tinea funguses such as tinea fungus such as trichophyton, epidermophyton rubrum, microsporon audouini and star-shaped nocardias.
Medulla Tetrapanacis: sweet in the mouth, light, cold nature; Enter lung, stomach warp.Diuretic, lactogenesis.The puckery pain of main stranguria, dysuria, edema, jaundice, damp-warm diseases, oliguria with reddish urine, puerperal, breast was few, amenorrhea, leukorrhagia, hygropyrexia dark coloured urine, edema oliguria." Changsha medicine solution " carries: " stimulate the menstrual flow and close, treat jaundice, eliminating carbuncle cellulitis, sharp nose carbuncle, except vexed.”
Radix Ribis davidii: puckery, hardship, slightly warm in nature; Return liver,spleen,kidney warp.Blood circulation promoting and blood stasis dispelling, relaxing muscles and tendons is regulated the flow of vital energy.Cure mainly rheumatic arthritis, menoxenia, amenorrhea lumbago, puerperal abdonimal pain, dysentery." Xinhua's book on Chinese herbal medicine outline " carries: " have the function of relaxing muscles and tendons to promote blood circulation, stasis-dispelling and pain-killing, bone and muscle strengthening.For rheumatic arthritis, menoxenia, lumbago.”
Herba Osbeckiae: acrid in the mouth, light, property is flat; Return lung, spleen, liver, large intestine channel.The dampness removing that reduces phlegm, hemostasis by removing blood stasis, removing toxic substances and promoting subsidence of swelling.Main cough, asthma, dysentery, has loose bowels, and spits blood, and spitting of blood, has blood in stool, amenorrhea, infantile malnutrition, rheumatic ostalgia, traumatic injury." Nanning City's medicine will " carries: " eliminating blood stasis to promote regeneration of blood, pain relieving convergence.Control interior external haemorrhage, infantile malnutrition, ulcerative gingivitis, toothache, cough.”
The present invention compared with prior art, has following beneficial effect:
The selected medical material compatibility of medicine of the present invention is suitable, meet Chinese medicine and pharmacy and modern medicine theory, and there is effect of the body resistance strengthening and constitution consolidating, benefiting QI and nourishing blood, circulation of qi promoting dissipating blood stasis, reducing swelling and alleviating pain, treatment menoxenia is had to significant curative effect, taking convenience, safe and reliable, have no side effect, period in a medicine can normally be worked and live, short treating period, instant effect, non-relapse after healing, application should be widely promoted.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
Raw material composition and the weight of effective ingredient of the present invention are:
Herba Strobilanthis Japonici 49g Folium Prinsepiae Utilis 47g Fructus Crataegi 46g Serpentis pimple 43g
Herba Ocimi (Herba Ocimi Pilosi) 43g Herba Iresines Herbstii 39g Herba Verbenae 38g Angelica niyida Wolff[A. ching-haiensis Shan xe K. T. Fu 36g
Flos Begoniae Evansianae 35g Cortex Cinnamomi 35g Folium Pini 34g Caulis et Folium Lactucae sativae 33g
Pericarpium Granati 32g Medulla Tetrapanacis 32g Radix Ribis davidii 30g Herba Osbeckiae 26g.
The preparation method of medicine of the present invention, comprises following processing step:
(1) Herba Strobilanthis Japonici, Folium Prinsepiae Utilis, Angelica niyida Wolff[A. ching-haiensis Shan xe K. T. Fu, Flos Begoniae Evansianae, Cortex Cinnamomi, Caulis et Folium Lactucae sativae, Pericarpium Granati, Medulla Tetrapanacis and Radix Ribis davidii are cleaned, put into container, add the distilled water of 8～10 times of amounts, soak after 5～6 hours, boil 3～4 hours, extract; Again add 6～8 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, the thick paste that at 60 DEG C of simmer down tos, relative density is 1.10～1.13, for subsequent use;
(2) Fructus Crataegi, Herba Ocimi (Herba Ocimi Pilosi), Herba Iresines Herbstii and Herba Verbenae are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(3) Serpentis pimple and Folium Pini are put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(4) Herba Osbeckiae is cleaned, immersed 80% the alcohol solution dipping 1～2 hour of 5 times of amounts, heating extraction 3 hours, reclaims ethanol, filters, and obtains filtrate, and the thick paste that at 65 DEG C of simmer down tos, relative density is 1.12～1.16 is for subsequent use;
(5) above-mentioned steps (1)～(4) prepared thick paste, juice and fine powder are mixed, make medicated powder granule, obtain the medicine for the treatment of menoxenia of the present invention.
Usage and dosage: oral, warm boiled water after meal, every day 3 times (each 1 time of morning, noon and afternoon), each 1 bag (every bag of 15g); Within 5 days, be 1 course for the treatment of, can fully recover 2～3 courses for the treatment of, and the person of being in a bad way follows the doctor's advice and drinks the amount of adding.
Embodiment 2
Raw material composition and the weight of effective ingredient of the present invention are:
Herba Strobilanthis Japonici 45g Folium Prinsepiae Utilis 43g Fructus Crataegi 42g Serpentis pimple 39g
Herba Ocimi (Herba Ocimi Pilosi) 39g Herba Iresines Herbstii 36g Herba Verbenae 34g Angelica niyida Wolff[A. ching-haiensis Shan xe K. T. Fu 32g
Flos Begoniae Evansianae 31g Cortex Cinnamomi 31g Folium Pini 30g Caulis et Folium Lactucae sativae 29g
Pericarpium Granati 28g Medulla Tetrapanacis 28g Radix Ribis davidii 26g Herba Osbeckiae 23g.
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 3
Raw material composition and the weight of effective ingredient of the present invention are:
Herba Strobilanthis Japonici 41g Folium Prinsepiae Utilis 39g Fructus Crataegi 38g Serpentis pimple 35g
Herba Ocimi (Herba Ocimi Pilosi) 35g Herba Iresines Herbstii 32g Herba Verbenae 30g Angelica niyida Wolff[A. ching-haiensis Shan xe K. T. Fu 28g
Flos Begoniae Evansianae 27g Cortex Cinnamomi 27g Folium Pini 26g Caulis et Folium Lactucae sativae 25g
Pericarpium Granati 24g Medulla Tetrapanacis 24g Radix Ribis davidii 22g Herba Osbeckiae 20g.
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 4
Raw material composition and the weight of effective ingredient of the present invention are:
Herba Strobilanthis Japonici 38g Folium Prinsepiae Utilis 35g Fructus Crataegi 34g Serpentis pimple 31g
Herba Ocimi (Herba Ocimi Pilosi) 31g Herba Iresines Herbstii 28g Herba Verbenae 26g Angelica niyida Wolff[A. ching-haiensis Shan xe K. T. Fu 24g
Flos Begoniae Evansianae 23g Cortex Cinnamomi 23g Folium Pini 22g Caulis et Folium Lactucae sativae 21g
Pericarpium Granati 20g Medulla Tetrapanacis 20g Radix Ribis davidii 18g Herba Osbeckiae 17g.
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 5
Raw material composition and the weight of effective ingredient of the present invention are:
Herba Strobilanthis Japonici 34g Folium Prinsepiae Utilis 31g Fructus Crataegi 30g Serpentis pimple 27g
Herba Ocimi (Herba Ocimi Pilosi) 27g Herba Iresines Herbstii 25g Herba Verbenae 22g Angelica niyida Wolff[A. ching-haiensis Shan xe K. T. Fu 20g
Flos Begoniae Evansianae 19g Cortex Cinnamomi 19g Folium Pini 18g Caulis et Folium Lactucae sativae 17g
Pericarpium Granati 16g Medulla Tetrapanacis 16g Radix Ribis davidii 14g Herba Osbeckiae 14g.
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Clinical data:
1, case selection:
As the medicine for the treatment of menoxenia, select the routine clinical observation of menoxenia patient 240 of making a definite diagnosis, patient is divided into two groups for the treatment of group and matched groups, treatment group women's 120 examples, 17～46 years old age, 31.5 years old mean age, the course of disease 1～7 year at random; Matched group women 120 examples, 18～47 years old age, 32.5 years old mean age, the course of disease 1～7 year; The course of disease, the degrees of symptoms for the treatment of group and two groups of cases of matched group are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group is taken medicine of the present invention, oral, warm boiled water after meal, every day 3 times (each 1 time of morning, noon and afternoon), each 1 bag (every bag of 15g); Within 5 days, be 1 course for the treatment of, take continuously 2～3 courses for the treatment of, the person of being in a bad way follows the doctor's advice and drinks the amount of adding.
Matched group is taken Aifu Nuangong Wan, oral, one time 9 grams, 2～3 times on the one, the person of being in a bad way follow the doctor's advice drink the amount of adding.
3, efficacy determination:
(1) cure: menstrual cycle, amount of bleeding are abnormal or month premenstrual, the symptom such as stomachache and General Symptoms when menstrual period all disappears, and it is normal that menstrual cycle recovers.
(2) effective: above-mentioned symptom alleviates to some extent, menstrual cycle is gradually extensive normal.
(4) invalid: to be not improved by treatment menstrual cycle.
4, result:
Select in the treatment group of medicine of the present invention, cure 86 examples, effective 31 examples, invalid 3 examples, cure rate 71.7%, total effective rate 97.5%.
In matched group, cure 42 examples, effective 36 examples, invalid 42 examples, cure rate 35%, total effective rate 65%.
Above result demonstration, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is given an example:
1, clock, female, 19 years old, people from Changchun, Jilin.Patient monthly shifts to an earlier date 3-4 days menstrual period, blockage of menstruation, the breast side of body, breast and lower abdominal distention pain, used several method treatment, have no any improvement, take after 1 course for the treatment of of medicine of the present invention, above-mentioned symptom is clearly better, and menstruation obviously recovers, continue to take after 1 course for the treatment of of medicine of the present invention, return to premorbid normal condition menstrual period, stable disease, follows up a case by regular visits to not recurrence after 1 year.
2, beam, female, 22 years old, people from Nanjing.Patient's dysmenorrhea 3 years, irregular menstrual period, abdominal distention, lumbago, menstrual period pale complexion, breast side of body feeling of distension and oppression, soft unable, the empty string of pulse condition of knee joint, be mainly after diagnosing due to menoxenia institute extremely, take Drug therapy of the present invention, take after 1 course for the treatment of, symptom disappears to some extent, continue to take after 2 courses for the treatment of, pass through and return to premorbid normal condition, symptom disappears completely, has rosy cheeks, energetic, after 2 years, do not follow up a case by regular visits to and do not recur again.
3, in certain, female, 25 years old, people from Suzhou, Anhui.The regular menstruation of patient in advance, many through blood volume, takes the curative effect such as Tiaojing tablets, four material leenurus ball very micro-.Rear patient recommends to take medicine of the present invention through doctor and treats, take after 1 course for the treatment of, menstrual period, distending pain of the breast obviously alleviated, than two days in advance last month, also reduce to some extent through blood volume, then take after 2 courses for the treatment of menstrual period, inferior menstrual phase, distending pain of the breast symptom disappears substantially, and menstrual period, normovolemia are followed up a case by regular visits to after 1 year without recurrence.
4, Wang, female, 33 years old, Zhangzhou, Fujian people.Patient gives birth to and occurs the confusion of the menstrual cycle rear nearly half a year, delay 4-6 days, many through measuring, menses are dark red, the time lengthening of passing through 6-8 days, and with soreness of waist pain, tired unable, dull and sallow complexion, deep and hesitant pulse, tcm diagnosis is hepatic and renal YIN deficiency disorder of menstrual cycle, after taking 2 courses for the treatment of of medicine of the present invention, reduce through row amount, continue to take after 2 doses of medicines of the present invention, menstrual cycle is frequent, follows up a case by regular visits to without recurrence after half a year.
5, Lee, female, 28 years old, people from Nanchang.The symptoms such as patient's trouble is many through blood volume, clot is many are had a surplus for 1 year, pale complexion, spiritlessness and weakness, lumbosacral aching pain, dizziness and tinnitus.Once used western medical treatment poor effect.Take upon somebody's introduction medicine of the present invention, take after 1 course for the treatment of, above-mentioned disease disappears to some extent, continues to take after 3 courses for the treatment of, and inferior month menstrual period, menstrual blood loss, clot obviously reduce, and above-mentioned disease disappears completely, does not recur.
6, Zhao, female, 40 years old, Taiyuan, Shanxi people.Nearly menstruation half a year of patient is measured more than many, dripping month unclean sometimes, sometimes amount less, color is light red, and with blood stasis piece, the symptoms such as shortness of breath and fatigue, nervous, anorexia and loose stool, light red tongue, white and thin fur, thready pulse without strength, through B ultrasonic and gynecologial examination without extremely, doctor is diagnosed as menoxenia, and doctor advised is taken Drug therapy of the present invention, takes after 1 course for the treatment of, menstruation recovers to some extent, continue to take after 2 courses for the treatment of, menstruation recovery is normal, the recurrence of following up a case by regular visits to that so far there are no.
Claims (5)
1. a medicine for the treatment of menoxenia, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
23～47 parts of 26～50 parts of Serpentis pimples of 27～51 portions of Fructus Crataegis of 30～53 portions of Folium Prinsepiae Utilis of Herba Strobilanthis Japonici
16～40 parts of 18～42 parts of Angelica niyida Wolff[A. ching-haiensis Shan xe K. T. Fus of 21～43 portions of Herba Verbenae of 23～47 parts of Herba Iresines Herbstiis of Herba Ocimi (Herba Ocimi Pilosi)
13～37 parts, 14～38 portions of Caulis et Folium Lactucae sativaes of 15～39 parts of Folium Pinis of 15～39 portions of Cortex Cinnamomis of Flos Begoniae Evansianae
11～29 parts of 11～33 parts of Herba Osbeckiaes of 12～36 parts of Radix Ribis davidiis of 12～36 portions of Medulla Tetrapanaciss of Pericarpium Granati.
2. a kind of medicine for the treatment of menoxenia according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
27～43 parts of 30～46 parts of Serpentis pimples of 31～47 portions of Fructus Crataegis of 34～49 portions of Folium Prinsepiae Utilis of Herba Strobilanthis Japonici
20～36 parts of 22～38 parts of Angelica niyida Wolff[A. ching-haiensis Shan xe K. T. Fus of 25～39 portions of Herba Verbenae of 27～43 parts of Herba Iresines Herbstiis of Herba Ocimi (Herba Ocimi Pilosi)
17～33 parts, 18～34 portions of Caulis et Folium Lactucae sativaes of 19～35 parts of Folium Pinis of 19～35 portions of Cortex Cinnamomis of Flos Begoniae Evansianae
14～26 parts of 14～30 parts of Herba Osbeckiaes of 16～32 parts of Radix Ribis davidiis of 16～32 portions of Medulla Tetrapanaciss of Pericarpium Granati.
3. a kind of medicine for the treatment of menoxenia according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
31～39 parts of 34～42 parts of Serpentis pimples of 35～43 portions of Fructus Crataegis of 38～45 portions of Folium Prinsepiae Utilis of Herba Strobilanthis Japonici
24～32 parts of 26～34 parts of Angelica niyida Wolff[A. ching-haiensis Shan xe K. T. Fus of 28～36 portions of Herba Verbenae of 31～39 parts of Herba Iresines Herbstiis of Herba Ocimi (Herba Ocimi Pilosi)
21～29 parts, 22～30 portions of Caulis et Folium Lactucae sativaes of 23～31 parts of Folium Pinis of 23～31 portions of Cortex Cinnamomis of Flos Begoniae Evansianae
17～23 parts of 18～26 parts of Herba Osbeckiaes of 20～28 parts of Radix Ribis davidiis of 20～28 portions of Medulla Tetrapanaciss of Pericarpium Granati.
4. a kind of medicine for the treatment of menoxenia according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
35 parts of 38 parts of Serpentis pimples of 39 portions of Fructus Crataegis of 41 portions of Folium Prinsepiae Utilis of Herba Strobilanthis Japonici
28 parts of 30 parts of Angelica niyida Wolff[A. ching-haiensis Shan xe K. T. Fus of 32 portions of Herba Verbenae of 35 parts of Herba Iresines Herbstiis of Herba Ocimi (Herba Ocimi Pilosi)
25 parts, 26 portions of Caulis et Folium Lactucae sativaes of 27 parts of Folium Pinis of 27 portions of Cortex Cinnamomis of Flos Begoniae Evansianae
20 parts of 22 parts of Herba Osbeckiaes of 24 parts of Radix Ribis davidiis of 24 portions of Medulla Tetrapanaciss of Pericarpium Granati.
5. a preparation method for the treatment of the medicine of menoxenia as described in claim 1～4 any one, is characterized in that: comprise following processing step:
(1) Herba Strobilanthis Japonici, Folium Prinsepiae Utilis, Angelica niyida Wolff[A. ching-haiensis Shan xe K. T. Fu, Flos Begoniae Evansianae, Cortex Cinnamomi, Caulis et Folium Lactucae sativae, Pericarpium Granati, Medulla Tetrapanacis and Radix Ribis davidii are cleaned, put into container, add the distilled water of 8～10 times of amounts, soak after 5～6 hours, boil 3～4 hours, extract; Again add 6～8 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, the thick paste that at 60 DEG C of simmer down tos, relative density is 1.10～1.13, for subsequent use;
(2) Fructus Crataegi, Herba Ocimi (Herba Ocimi Pilosi), Herba Iresines Herbstii and Herba Verbenae are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(3) Serpentis pimple and Folium Pini are put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(4) Herba Osbeckiae is cleaned, immersed 80% the alcohol solution dipping 1～2 hour of 5 times of amounts, heating extraction 3 hours, reclaims ethanol, filters, and obtains filtrate, and the thick paste that at 65 DEG C of simmer down tos, relative density is 1.12～1.16 is for subsequent use;
(5) above-mentioned steps (1)～(4) prepared thick paste, juice and fine powder are mixed, make medicated powder granule, obtain the medicine for the treatment of menoxenia of the present invention.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410168358.5A CN103893415A (en) | 2014-04-24 | 2014-04-24 | Medicine for treating irregular menstruation and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410168358.5A CN103893415A (en) | 2014-04-24 | 2014-04-24 | Medicine for treating irregular menstruation and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107875313A (en) * | 2017-12-17 | 2018-04-06 | 佛山市赛普斯科技服务有限公司 | A kind of Chinese medicine preparation to restore menstrual flow and invigorate blood circulation and preparation method thereof |
| WO2019122783A1 (en) * | 2017-12-21 | 2019-06-27 | Claripharm | Dietary supplements and use thereof on menses |
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| 孙伟等: "中医药治疗***的研究进展", 《世界临床药物》 * |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107875313A (en) * | 2017-12-17 | 2018-04-06 | 佛山市赛普斯科技服务有限公司 | A kind of Chinese medicine preparation to restore menstrual flow and invigorate blood circulation and preparation method thereof |
| WO2019122783A1 (en) * | 2017-12-21 | 2019-06-27 | Claripharm | Dietary supplements and use thereof on menses |
| FR3076208A1 (en) * | 2017-12-21 | 2019-07-05 | Claripharm | FOOD SUPPLEMENTS AND THEIR USE ON MENSTRUATIONS |
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Application publication date: 20140702 |