CN103884697A - Biological agent detection alarm apparatus - Google Patents
Biological agent detection alarm apparatus Download PDFInfo
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- CN103884697A CN103884697A CN201410020333.0A CN201410020333A CN103884697A CN 103884697 A CN103884697 A CN 103884697A CN 201410020333 A CN201410020333 A CN 201410020333A CN 103884697 A CN103884697 A CN 103884697A
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Abstract
The invention discloses a biological agent detection alarm apparatus, which is a sensor capable of detecting several substances by development. The biological agent detection alarm apparatus comprises the following processes: sampling, inspecting and identifying through a trigger and a prompting device; carrying out noise inhibition and amplification on a signal of the sensor by using a weak signal detection technology; and identifying whether the substances exist, if so, transmitting corresponding alarm information, and reminding related personnel to take corresponding preventive measures, so that the chances of infection are reduced, the life and properties of people are protected, and diffusion is prevented.
Description
technical field:
What the present invention relates to is a kind of biological agent detection alarm device, belongs to report biological technical field.
background technology:
The technical merit such as bacterial detection, virus, toxin is low in the market, often can produce various viral diseases of being taken by surprise, and in order fast detecting to go out various infection bacteriums, carries out the preparation of timely prevention.The present invention adopts biological agent detection alarm device system to carry out bacterial detection virus, in the time biological agent virus being detected, can pass to related personnel by alarm fast, can prevent in time the generation of various biological agent viruses.Gordian technique of the present invention and development difficult point are sensitive element manufacturing technologies.At present domestic in the manufacturing technology of biosensor, compared with external advanced technology, gap is larger.Particularly aspect laser-sensitive element.Because this class technology and product are mainly used in military industry field, import and export restrictedly, be difficult for buying, and expensive.Therefore, instrument can only adopt domestic sensitive element.And at present domesticly there is no ready-made available sensitive element of new generation, so the development of instrument is from sensitive element.
In addition, the key problem in technology of photoionization detector sensor is at ultraviolet (UV) lamp.Meet instrument and be suitable for the UV lamp requiring, the one, there is the energy of regulation, the 2nd, overall volume microminiaturization; So the development process of sensor is emphasis.
summary of the invention:
In order to meet the need of market; prevent various bacteriums, viral communication, biological agent detection alarm device of the present invention, is the sensor that can detect these several materials by development; adopt again Technique of Weak Signal Detection to carry out noise suppression, amplify and process the signal of sensor; and identify whether there is the existence of above material, if had, send corresponding warning message; prompting related personnel takes the corresponding precautionary measures; reduce and infect probability, protection people's lives and properties, and prevent diffusion.Its biological agent is to refer in particular to bacterium, virus, toxin etc., is mainly these five kinds of anthrax, the plague, smallpox virus, botulinum toxin and ricin (WA)s.The principle of work of biological agent detection alarm device system is that airborne background gasoloid is analyzed and sensing, then utilize sampling thief to be carried out the sampling of simmer down to late detection, the detection sample gathering enters detecting device and carries out specific recognition, by judging whether biological agent material after identification system analysis and identification.
System comprises: trigger/suggestion device unit, biological collector unit, detector cell, gas circuit unit, embedded system unit, Bioexperiment chamber unit and the several parts of power module design cell, wherein, technical research emphasis is fluorescence detector.
accompanying drawing explanation:
Fig. 1 is the theory diagram of biological detection;
Fig. 2 is the detection scheme design drawing of bioaerosol sensor;
Fig. 3 is air-channel system fundamental diagram;
Fig. 4 is the composition diagram of aspiration pump;
Fig. 5 is power module figure.
embodiment:
Shown in Figure 1, trigger/suggestion device is designed and developed, trigger: its work time need to set up background gas colloidal sol level in a specific place, the variation of the aerosol particle subnumber that then sensing occurs under this background, background gas sol particles number is changed and indicated, thereby provide early warning for sampling.Suggestion device: measure when occur increasing of aerosol particle subnumber, and can distinguish bioaerosol and abiotic aerocolloidal concentration (non-specific detection of biological field agents).Particle measurement: measurement has particular dimensions and (is generally the m) relative populations of particle of 0.5 μ m～30 μ.Method is as follows:
1, aerodynamics particle sizing (APS) technology;
2, high flux aerodynamic particle size clasfficiator (HVAPS);
3、Met-One。
Shown in Figure 1, biological collector, because biological warfare agent extremely low in air is difficult to be detected, but really can cause serious effect, therefore need a device-sampling thief/gatherer that particle/gasoloid in air-flow is concentrated, it is sampled to atmosphere and airborne particle is concentrated in a liquid medium for analyzing.When gatherer is received the signal that to change appearred in expression background level that trigger sends, just start air sampling, more airborne particle is concentrated in a liquid medium.For the discriminating parts of biological detection system provide " raw material ", be also determinacy identification and forensic identification analysis sampling simultaneously.Sampling thief: be mainly used in collecting the particle that some need be measured, method has following:
1, granularity selection sampling thief or shock sampling thief,
2, virtual impact sampling thief,
3, cyclone sampling thief,
4, hand held type sampling case,
5, hand-held sampler.
Shown in Fig. 1, Fig. 2, detecting device, detecting device (specific recognition technology) is parts or instrument, they can identify suspicious biological warfare agent (bacterium or virus war agent) to the level of " kind " and the type of toxin.Specific recognition technology is that a specific biological label of holding according to this biological warfare agent of detection completes; Detection system based on the Discr. of antibody for speed and robotization are had relatively high expectations.Method is as follows:
1) immunological technique: immuno analytical method is the detection with corresponding antibody height selectivity combination to antigen (exotic of health), realizes by forming antigen-antibody complex, is the specificity that depends on Ag-Ab combination.Immunoassay can be divided into 3 classes:
1. can abandon matrix type device (test-strips and testing cassete)
2. usage flag reagent is measured the biology sensor of the anti-body combination of antigen indirectly
3. do not need the biology sensor of label (directly affinity analyzing method)
2) nucleic acid amplification: with the DNA and the RNA that help bacterial detection and the virus existence of direct-detection toxin (nucleic acid amplification itself the can not) agent of fighting.Sample for foranalysis of nucleic acids can directly obtain from field, be cultivated or obtained from infection animal or people's tissue by testing laboratory.Mini PCR utilizes the graceful chemical reaction reagent of process and Tyke of polymerase chain reaction, and a suspicious sample is put into one can Fast Heating and cooling low profile thermal circulating instrument, has embedded a small-sized optical system in this thermal cycler.
Shown in Fig. 3, Fig. 4, air-channel system principle of work: air (sample gas) enters detecting device by admission piece aperture around by filter paper, then passes through aspiration pump, is discharged by exhausr port.Its Main Function is that air (sample gas) is drawn into detecting device, is irradiated by ultraviolet ray, forms fluorescence, by light sensor output electrical signals, amplifies through micro current amplifier.Sample gas is finally discharged by exhausr port.The sample gas embedded system exploitation of discharging finally enters biology laboratory and detects, if had, sends corresponding warning message, and prompting related personnel takes the corresponding precautionary measures, and reduce and infect probability, protection people's lives and properties, and prevent diffusion.
Shown in Figure 5, power module, the outer power supply source of instrument is Vehicular accumulator cell (12V or 24V).For meeting the power supply requirement of the each unit of instrument, and meet the index of complete machine electromagnetic compatible and reliability, adopt DC-DC power module and EMI module.Outer power supply source: 12V ± 20% (9.6～14.4V), supply voltage during lower than 9.6V, has under-voltage indication.For guaranteeing the safety of DC-DC power module, module is provided under-voltage protection function for oneself.
Claims (7)
1. biological agent detection alarm device, comprise trigger/suggestion device unit, biological collector unit, detector cell, gas circuit unit, embedded system unit, Bioexperiment chamber unit and the several parts of power module design cell, it is characterized in that middle technical research emphasis is fluorescence detector.
2. according to claim 1, trigger/suggestion device, it is characterized in that, trigger: its work time need to set up background gas colloidal sol level in a specific place, the variation of the aerosol particle subnumber that then sensing occurs under this background, background gas sol particles number is changed and indicated, thereby provide early warning for sampling; Suggestion device: measure when occur increasing of aerosol particle subnumber, and can distinguish bioaerosol and abiotic aerocolloidal concentration (non-specific detection of biological field agents).
3. according to claim 1, biological collector, it is characterized in that, because biological warfare agent extremely low in air is difficult to be detected, but really can cause serious effect, therefore need a device-sampling thief/gatherer that particle/gasoloid in air-flow is concentrated, it is sampled to atmosphere and airborne particle is concentrated in a liquid medium for analyzing.
4. according to claim 1, detecting device, it is characterized in that, detecting device (specific recognition technology) is parts or instrument, and they can identify suspicious biological warfare agent (bacterium or virus war agent) to the level of " kind " and the type of toxin; Specific recognition technology is that a specific biological label of holding according to this biological warfare agent of detection completes; Detection system based on the Discr. of antibody for speed and robotization are had relatively high expectations.
5. according to claim 1, air-channel system, is characterized in that, air-channel system principle of work: air (sample gas) enters detecting device by admission piece aperture around by filter paper, then passes through aspiration pump, is discharged by exhausr port; Its Main Function is that air (sample gas) is drawn into detecting device, is irradiated by ultraviolet ray, forms fluorescence, by light sensor output electrical signals, amplifies through micro current amplifier, and sample gas is finally discharged by exhausr port.
6. according to claim 1; embedded system, biology laboratory; it is characterized in that; the sample gas embedded system exploitation of discharging finally enters biology laboratory and detects, if had, sends corresponding warning message; prompting related personnel takes the corresponding precautionary measures; reduce and infect probability, protection people's lives and properties, and prevent diffusion.
7. according to claim 1, power module, is characterized in that, the outer power supply source of instrument is provided.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410020333.0A CN103884697A (en) | 2014-01-17 | 2014-01-17 | Biological agent detection alarm apparatus |
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| CN201410020333.0A CN103884697A (en) | 2014-01-17 | 2014-01-17 | Biological agent detection alarm apparatus |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111529225A (en) * | 2020-06-12 | 2020-08-14 | 吉林大学 | Ambulance with function of immediately detecting new coronavirus in air |
| CN113005027A (en) * | 2020-11-25 | 2021-06-22 | 中国矿业大学 | Device and method for measuring distribution of microbial particles in air |
-
2014
- 2014-01-17 CN CN201410020333.0A patent/CN103884697A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111529225A (en) * | 2020-06-12 | 2020-08-14 | 吉林大学 | Ambulance with function of immediately detecting new coronavirus in air |
| CN113005027A (en) * | 2020-11-25 | 2021-06-22 | 中国矿业大学 | Device and method for measuring distribution of microbial particles in air |
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Application publication date: 20140625 |
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